miki lee / oeb 192 – 08.11.12 mobile genetic elements and adaptive mutation
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Miki Lee / OEB 192 – 08.11.12
Mobile genetic elements and adaptive mutation
IS familyhttp://www-is.biotoul.fr/
Effects on bacterial evolution
• An important source of genetic variation– Insertion
– Homologous recombination
Effects on bacterial evolution
— M-evolved— S-evolved— M+S-evolved— M/S-evolved
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MutationLuria–Delbrück experiment Cairns–Foster system
Modified Cairns–Foster system
Kugelberg E. et.al. PNAS 2006;103:17319-17324
Monday (11/17): Physiological basis of fitness
Upcoming talks
Tuesday, 12/16Rich LenskiMichigan State University12:30 pm, 341 Warren Alpert (HMS)