Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer Review of Information Transfer in

Cell Recombination Transfer of DNA &Genetic

Recombination in Bacteria– Conjugation– Transformation– Transduction

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer Recombination – process by which DNa is

broken and repaired resulting in an exchange of DNA between two DNA molecules to form new combinations of genes

Eukaryotic - crossing over during meiosis Prokaryotic - occurs when DNA is

transfered from one cell to another (transfer from a doner to a recipient)

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer

GeneticRecombination

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer

Conjugation

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer

Normal or Low Frequency Conjugation

Microbial Genetics - DNA Microbial Genetics - DNA TransferTransfer

High Frequency Conjugation

Transformation

Transduction

Microbial Genetics - Microbial Genetics - RegulationRegulation Three types of regulation

– Constitutive - gene is always turned on

– Repression - gene is normally turned on but can be turned off in response to a metabolic signal

– Induction - gene is normally turned off but can be turned on in response to a metabolic signal

Microbial Genetics - Microbial Genetics - RegulationRegulation Types of

Regulation of mRNA synthesis– Induction - lac

operon– Repression - trp

operon

Microbial Genetics - Microbial Genetics - RegulationRegulation