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  • Dr Ganesh K Saini

    Product Manager - Poultry

    The Assurance Minerals

  • Classified into two groups: Macro or major elements (required > 100 ppm) 7 macro minerals are Ca, P, Mg, Na, K, Cl and S

    Micro or trace mineral elements (required

  • Soil Plant

    Bird

    Relationship

  • Emerging Nutrient Deficiencies in soils as a Result of Increased Food Production (Swarup & Ganeshamurthy, 1998)

    Year 1950 1960 70 80 1990 2000

    Food

    Production

    50mt 70mt 108 112 172 209mt

    Emerging

    Nutrient

    Deficiencies

    ?

    N N N N N N

    Fe Fe Fe Fe Fe

    P P P P

    Zn Zn Zn Zn

    K K K K

    S S S

    Mn Mn Mn

    B B

    ?

  • REGIONS Minerals deficient in feeds

    Northern Ca , P , Mg, Zn ,Cu, Mn, I,

    Western Ca, P, S, Cu, Zn,

    Southern Ca, P, Mg, Cu, Zn,

    Eastern Ca, P, Mg, Mn, Cu, Zn, Co,

    Mineral Deficiency in feeds All

    India

  • The arrows indicate

    the relationship

    between the minerals.

    If a mineral has an

    arrow pointing to

    another mineral, it

    indicates that mineral

    is a requirement for

    absorption.

    How to Interpret the

    Mineral Wheel

  • Sub-Clinical Clinical

    Immune Function

    Growth or Fertility

    Clinical Signs

    Time

    Min

    era

    l S

    ta

    tu

    s

    Mineral Deficiency

    Response

  • 10

  • TRACE MINERAL ABSORPTION

  • Zn+2

    Zn+2

    Ingested

    CB - 50

    Outcome 1. Excretion

    Blood

    Gut Wall

  • Zn+2

    Zn+2

    Zn+2

    Ingested

    CB - 50

    Outcome 2. Excretion

    Antagonist

    Blood

    Gut Wall

  • Zn+2

    Zn+2

    Zn+2 +

    Ingested

    CB - 50

    Complexing

    Agent

    Outcome 3. Natural Success

    Blood Zn+2

    Gut Wall

  • Ingested

    Gut Wall

    Engineered for Success

    Zn+2

    Zn+2

    Zn+2

    Zn+2

    Zn+2 BLOOD

  • 18

  • What about Chelation?

    Chelation . . . The process by which metal ions form a

    complex with an organic ligand via a coordinate bond.

    19

    From: Holwerda, R. A., R. C. Albin and F. C. Madsen (1995) Chelation effectiveness of zinc proteinates demonstrated, Feedstuffs, June 19, 1995, 12-13 and 23.

  • Assured Response

    Assured Results

    Assured Bioavailability

    Assured Returns

  • Complexed to Metal

    Amino Acid

  • 22

  • TRACE MINERALS ARE NOT

    THE SAME

    Sulfates

    Proteinates

    EDTA

    Oxides Carbonates

    Chlorides Chelates complex

  • Metal (Specific Amino Acid) Complex

    Metal Amino Acid Chelate

    Metal Amino Acid Chelate

    Metal Proteinate

    Metal Polysaccharide Complex

    Metal Propionate

    CPX - 22

    DIFFERENTIATION OF ORGANIC TRACE MINERALS

    Zn+2 Prop.-1 Prop.-1

    Zn AA

    AA AA AA

    Zn Zn

    AA AA

    Zn Zn

    Zn Zn

    Zn Zn

    Zn Zn Zn Zn

    Zn Zn Zn

    Zn

    Zn Zn

    Zn

    Met Zn

    AA Zn AA AA

    AA AA

    AA

    AA AA AA AA

    AA AA

    AA

    AA AA AA

    AA AA

    AA

  • Absorption

    SIZE MATTERS

    Need to be

  • SMALLER IS BETTER!

  • ORGANIC TRACE MINERAL COMPARISON (Based on AAFCO)

    PROTEINATE

    M

    M

    360

    Daltons

    1065

    Daltons

    AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein

  • THIS IS ALSO A PROTEINATE

    6365 Daltons

    AFFCO Definition of Proteinate: The product resulting from the chelation of a soluble salt with amino acids and/or partially hydrolyzed protein

  • DIGESTION

    Most Large Peptides and Protein Ligands will be

    Broken Into Single Amino Acids, Di- or Tripeptides

    for absorption

    The Digestion Process Will Destroy the Weak

    Bond Between the Metal and the Peptide or

    Protein Ligand

    Z CPX - 38

  • Relative Stability Constant of OTM

    0

    20

    40

    60

    80

    100

    120

    Amino Acid Di- Peptide Tri- Peptide Peptide (4

    AA)

    Peptide (5

    AA)

    Stability Constant %

    LIGAND TYPE

    Rel

    ati

    ve

    Sta

    bil

    ity

    Co

    nst

    an

    t %

    Science also confirms that as the ligand

    size increase the ability of the ligand to

    form a strong bond decrease rapidly.

  • FORMULATION STRATEGIES FOR LOWERING TRACE MINERAL

    SUPPLEMENTATION LEVELS

    Parameter

    Increasing Trace Mineral Level

    Inorganic Complexes

    Nutrient Utilization Status vs. Time and Level Performance Single Source - All Complexes Immunity Environment

    CB - 42.2

    Inorganic + Antagonists

  • Parameters Methomin Bioplex

    Type Amino acid Chelate Proteinate

    Metal Bond 1:2 (metal: AA) Metal bonded with a protein

    molecule

    Molecule Size Below 360 dalton More than 1000 dalton

    Composition 40,40,5,15 of Zinc,

    Manganese, Copper and

    Iron respectively.; Iodine and

    chromium thru inorganic

    route and Se thru Selenium

    yeast route.

    Research Published data mostly in

    popular magazines

  • Prevent Deficiency

    Normal growth

    Normal Repro

    Normal immunity

    Increased growth

    Improved Efficiency

    Improved Reproduction

    Improved immunity

    STANDARD MINERALS

    Assurance

    MINERALS

  • Assured Response

    Assured Results

    Assured Bioavailability

    Assured Returns

  • 35 35

    Methomin SPL

    Zinc 40 grams

    Manganese 40 grams

    Copper 10 grams

    Iron 12 grams

    Chromium 250 mg

    Iodine 4 grams

    Selenimum 300 mg

    Cobalt 250 mg

    Mixing Rate : 0.5 - 1 Kg / MT

    35

    Per Kg METHOMIN TOTAL Contains

  • Advantage of Methomin

    Egg quality: shell quality,albumin quality,nutritional value of egg, free

    from defects.

    Zinc helps in activation of carbonic anhydrase and formation of cuticle

    Blood plasma - shell gland - egg shell

    36

  • Benefits

    Source of methionine.

    Reduction in egg shell breakage.

    Improvement in egg shell quality.

    Improvement in hatchability

    Growth and feed efficiency.

    Improves egg production.

    Better performance during heat stress

    37

  • MHA V/S DLM

    38

    MHA DLM

    Absorbed throughout the intestinal tract Absorbed mainly in the ileum

    Absorption is a passive process Is active process

    Converted to L-methionine much faster Comparatively slower conversion

    Absorption is unaffected by heat stress Decreases during heat stress

    Non-toxic at higher doses Toxic at higher doses

  • Objective

    1. Reduction of antagonism, interferences and competition among

    minerals.

    2. Improve the bioavailability of minerals

    3. Counteract antinutritional factors, which affecting minerals

    4. Performance improvement

    5. Health improvement (immune status, functional nutrition)

    6. Over all animal welfare

    7. Improvement in animal produces quality (meat, milk, egg, wool etc.,)

    8. Reduce degenerative effect of trace minerals on vitamins in premixes

    feed.

    9. Protect environment by reducing metal pollution.

    39

  • Mixing Rate and Presentation

    Mixing Rate : Poultry -0.5-1Kg/ton of feed

    As recommended by the Nutritionist

    Presentation : 25Kg.

    40