mesoporous silica nanospheres as mri contrast agents
DESCRIPTION
Mesoporous Silica Nanospheres as MRI Contrast Agents. J. Am. Chem. Soc . 2008 , 130 , 2154-2155. a). b). c). d). e). f). Post-Synthetic Modifications of MIL-101 Nanoparticles for Targeted Delivery of Cisplatin and Optical Contrast Agents. - PowerPoint PPT PresentationTRANSCRIPT
Mesoporous Silica Nanospheres as MRI Contrast Agents
J. Am. Chem. Soc. 2008, 130, 2154-2155.
NN
N
O
O
OO
O
O
O
OGdSi
OH2OH2
O
OO
=Gd-S i-DTTA
NN
N
O
O
OO
O
O
O
O
GdSi
OH2OH2
O
OO=
NN
N
O
O
OO
O
O
O
Gd
Si
OH2O
OO
NHSS
OO
MSN-Gd
MSN-Gd-1
= NN
N
O
O
OO
O
O
O
Gd
OH2
NHHS
OO
cleaved from MSN-Gd-1 and cleared from kidney in vivo
a) b)
c) d)
e) f)
Post-Synthetic Modifications of MIL-101 Nanoparticles for Targeted Delivery of Cisplatin and Optical Contrast Agents
Taylor-Pashow, K.M.L.; Della Rocca, J.; Xie, Z.; Tran, S.; Lin, W. J. Am. Chem. Soc. 2009, 131, 14261-14263.
Highly Porous Metal- and Covalent-Organic Frameworks
Manuscript submitted.
J. Am. Chem. Soc. 2010, in press.Nat. Chem. 2010, 2, 838-846.