Meningitis vaccines

Dr Brenda CorcoranNational Immunisation Office

World Meningitis Day24 April 2018www.immunisation.ie

: Dates vaccines introduced into the Irish immunisation schedule

Vaccine Date introduced

Hib 1992MenC (catch up 2000-2002) 2000Hib booster (catch up 2005) 2006PCV7 (catch up 2008-10) 2008PCV13 2010MenC (adolescent booster) 2014MenB 2016

• Non live vaccines• Can be given on same day or at any interval from other vaccines

Hib vaccine

• Part of 6in1 vaccine (Infanrix hexa) – 2, 4 and 6 months – Must be reconstituted

• Booster (Menitorix)– Hib/MenC combined at 13 months

• Late entrant – 1 dose up to 10 years of age

www.immunisation.ie

www.immunisation.ie

MenC vaccine• MenC (Menjugate) at 6 months• Hib/MenC combined vaccine at 13 months

• Concerns about waning immunity in adolescents– MenC booster introduced for 1st years in 2014/15– No catch up programme

• Late entrant – 1 dose up to 23 years

• MenACWY vaccine recommended in UK since 2015/2016 (including catch up for college students)– Under review by NIAC – no change to date

www.immunisation.ie

PCV vaccine

• PCV13 (Prevenar13) at 2 and 6 months• Booster PCV13 (Prevenar13) at 13 months

• Late entrant – 1 dose up to 2 years

www.immunisation.ie

MenB vaccine• MenB (Bexsero) at 2 and 4 months• Booster MenB (Bexsero) at 13 months

• Late entrant (born on or after 1/10/16)

• Prophylactic paracetamol required up to 12 months when given with other PCI vaccines

Age No. of doses Timing

3 to <10 months 3 2 doses 2 months apart,

3rd dose at >12 months at least 2 months after dose 2

10 months and older 2 2 doses 2 months apart

Vaccine uptake rate at 24 months1999-2017

Target 95%

www.immunisation.ie

95% Hib3 92% PCVb90% Hibb 88% MenCb

Source: HPSC

MenCb uptake at 24 months Q4 2017

www.immunisation.ieSource: HPSC

Vaccine uptake at 12 months 2000- 2017

www.immunisation.ie

91% MenB2 89% Hib388% MenC1 88% PCV2

Source: HPSC

Target 95%

MenC1 uptake at 12 months Q4 2017

www.immunisation.ieSource: HPSC

MenC booster uptake 2014/15 – 2016/17

www.immunisation.ie

Medically at risk

For more details see new Chapters of the Immunisation Guidelines (to be published shortly)https://www.hse.ie/eng/health/immunisation/hcpinfo/guidelines/immunisationguidelines.html

www.immunisation.ie

MenACWY MenB PCV Hib

Asplenia and hyposplenism √ √ √ √HIV infection √ √ √ XImmunomodulatory treatment √ √ X XHaematopoietic stem cell transplant √ √ √ √Solid organ transplant √ √ √ X

Vaccine supplies

• All vaccines available from the National Cold Chain Service(except for private/travel use)

• Single Hib vaccine (Hiberix) no longer available => use Hib/MenC (Menitorix) instead

• Any issues contact vacccines@udd.ie

www.immunisation.ie

www.immunisation.ie

23-29 April 2018

@HSEimm#vaccineswork#immunizeEurope