meningitis, encephalitis and brain abscess_aaims_hbd_iv-1[1]

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Meningitis Encephalitis Brain abscess Diagnosis and Treatment Update Germaine Daley BSc, MSc (Clinical Microbiology) [email protected] [email protected]

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Meningitis and Encephalitis:

MeningitisEncephalitisBrain abscess

Diagnosis and Treatment Update

Germaine Daley BSc, MSc (Clinical Microbiology)

[email protected]

[email protected]

1

Objectives

Infections of the Nervous System

Meningitis

Encephalitis

Brain absess

C. Nolts

Infections of the Nervous System

Can include infections of the meninges (meningitis), the general brain parenchyma(encephalitis), or a focalized infection of the brain parenchyma (brain absess)

General Sx are fever and headache. Other Sx will exist depending on the etiology/nature.

Infections of the Nervous System

Untreated or improperly treated=high mortality

Neonates, young people, adults, old people, and immunocompromised(HIV) are distinctly different populations and this categorization is essential

Definitions

Meningitis inflammation of the meninges

Encephalitis infection of the brain parenchyma

Meningoencephalitis inflammation of brain + meninges

Aseptic meningitis inflammation of meninges with sterile CSF

6

Meningitis:

bacterial

viral

fungal

aseptic (Lyme, syphillis)

TB

Other causes of aseptic meningitis:

malignancy

NSAIDs

chemo

abx

Common causes of meningitis

#1 cause:

S. pneumoniae- in adults, very prevalent in others

N. meningitidis-in young people, characteristic rash

S. agalactiae (GBS)-in neonates

Other prominent causes:

Listeria-in children