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European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected] Membership Application ENOLL 9 TH WAVE 1. Basic Facts Living Lab (host) organisation Pre-registration number 030 Living Lab short name LILL Living Lab full name (title) Lecco Innovation Living Lab Host organisation name Univerlecco Host organisation VAT number 02951560131 Host organisation type Association Postal address Via Tonale 28/30 Post code 23900 City Lecco Country Italy Telephone (+39) 0341 292 271 Fax (+39) 0341 292 220 Web-site (URL) http://www.leccolivinglab.com Living Lab established [year] Practice 2004; Formalizazion: 2015; Living Lab manager / main contact person First name Vico Last name Valassi Title (Mr/Mrs/Ms) Mr Postal address Via Tonale 28/30 Post code, City 23900, Lecco Country Italy Email [email protected] 2. Membership Motivation Lecco Innovation Living Lab is first of all a way to formalize a long-term strategy and an ongoing practice started in 2004 in the fields of rehabilitation and strategic approach to innovation. By becoming an ENoLL member, LILL broaden its international appeal for students, researchers and practitioners and gain the possibility to make contacts within a network with similar interests and aims. Ideally, facilitating new connections to work together on EU projects (Horizon2020, AAL JPI). The membership is a strong assertion of the commitment on the partnership’s user-centric approach to foster wellbeing, maximize innovation and reduce costs. This goal is agreed upon and was made explicit by Regione Lombardia and Fondazione Cariplo, two of the main sponsors of the network’s projects. LILL can contribute to the development of an international innovation network in many ways: high technical and scientific expertise; a strong local network that includes all actors; EU contacts of its partners; contributions in policymaking; interest, willingness and assets host experimentation; a valuable consultant; and a receptive dissemination network. LILL’s interests perfectly fit in the Well Being and Health Thematic sub Group; other relevant themes are Social Innovation. Social Inclusion, Smart Cities. Future Internet. Internet of things and Future Internet, Living Labs and Social Innovation Convergence Work Group. LILL plans to become an effective ENoLL member in 2017.

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Page 1: membership application 9thwave compilazione wip2. Membership Motivation Lecco Innovation Living Lab is first of all a way to formalize a long-term strategy and an ongoing practice

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

Membership Application ENOLL 9TH WAVE

1. Basic Facts Living Lab (host) organisation

Pre-registration number 030 Living Lab short name LILL Living Lab full name (title) Lecco Innovation Living Lab Host organisation name Univerlecco Host organisation VAT number 02951560131 Host organisation type Association Postal address Via Tonale 28/30 Post code 23900 City Lecco Country Italy Telephone (+39) 0341 292 271 Fax (+39) 0341 292 220 Web-site (URL) http://www.leccolivinglab.com Living Lab established [year] Practice 2004; Formalizazion: 2015;

Living Lab manager / main contact person

First name Vico Last name Valassi Title (Mr/Mrs/Ms) Mr Postal address Via Tonale 28/30 Post code, City 23900, Lecco Country Italy Email [email protected]

2. Membership Motivation Lecco Innovation Living Lab is first of all a way to formalize a long-term strategy and an ongoing practice started in 2004 in the fields of rehabilitation and strategic approach to innovation. By becoming an ENoLL member, LILL broaden its international appeal for students, researchers and practitioners and gain the possibility to make contacts within a network with similar interests and aims. Ideally, facilitating new connections to work together on EU projects (Horizon2020, AAL JPI). The membership is a strong assertion of the commitment on the partnership’s user-centric approach to foster wellbeing, maximize innovation and reduce costs. This goal is agreed upon and was made explicit by Regione Lombardia and Fondazione Cariplo, two of the main sponsors of the network’s projects. LILL can contribute to the development of an international innovation network in many ways: high technical and scientific expertise; a strong local network that includes all actors; EU contacts of its partners; contributions in policymaking; interest, willingness and assets host experimentation; a valuable consultant; and a receptive dissemination network. LILL’s interests perfectly fit in the Well Being and Health Thematic sub Group; other relevant themes are Social Innovation. Social Inclusion, Smart Cities. Future Internet. Internet of things and Future Internet, Living Labs and Social Innovation Convergence Work Group. LILL plans to become an effective ENoLL member in 2017.

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Membership Application: ENoLL 9th Wave

Lecco Innovation Living Lab Page 2 of 19

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

3. Description and Characteristics LILL has two main interconnected areas of interest: health innovation and systemic approach to innovation. Health innovation is focused on rehabilitation and technologies for living environments, with ten years of experience in systemic projects for ecosystemic growth. The partnership has managerial, business, scientific, clinical and technical expertise on a wide range of topics. The projects are developed by a network consisting of Univerlecco, Politecnico di Milano Lecco Campus, four CNR (National Research Council of Italy) institutes, two IRCCS (Research Hospitals), a Rehabilitation Center, a users’ association (UILDM). Users’ needs are carefully analysed and debated with the involvement of all stakeholders. Then, projects are developed by researchers and practitioners, supported by a number of well-equipped laboratories, in close collaboration with enterprises. At the same time, the partnership has clinical expertise and hosts clinical trials in its several specialized centers that work with all age groups (pediatric, adult, geriatric) for validation. Features of the process are the exchange and joint development of clinical protocols, tight collaboration between physicians and biomedical engineers, multicenter pre-clinical and clinical trials, neuroimaging and diagnostics, technical, clinical and scientific evaluation of new therapies. LILL’s systemic approach to innovation is practically implemented through Univerlecco and its partners. The primary aim is to activate and interconnect the network as much as possible. As an example, a project has been developed through an iterative process of meetings and revision of all stakeholders, from a user association to technicians and clinitians to ensure the most effective result in answering a well defined need. Currently, the consortium has started applying for funding (e.g. Telethon Calls 2015) and is looking for further opportunities to support the implementation. Another example of this approach can be seen in “Business to Research”, a project launched in March 2014 that has seen many of the Living Lab partners involved as promoters or participants to the local network. The goal is to find shared interests between research institutions and companies and give researchers clues about which areas the local industry is more interested in. The same approach will be applied at an inter-regional level, on becoming part of a European network. The vision for the Lecco Innovation Living Lab is to become a single support and information interface for the whole system, which acts a distributed and externalized R&D laboratory. This will simplify and multiply relationships while dramatically decreasing costs and time to market, especially but not limited to rehabilitation and technologies for living environment. Even thought experience shows that the Lecco economic fabric virtually allows to build, test and bring to market anything that is found through research, in these fields validation, commercialization and acquisition are well-known bottlenecks. This way of operating has already been validated several times on a local and National scale: a first time in 2013, when Univerlecco became coordinator for the Lombardy Regional Cluster “Technologies for the Living Environment” <http://www.clustertav.lombardia.it>. The Cluster is an aggregation of research institutions, universities, associations, caregivers, cooperatives, SME and Large Corporates. Its aim is the “development of knowledge, technological solutions, plants, highly innovative buildings and products. According to Ambient Intelligence and Ambient Assisted Living paradigms, these afford a redesign of the (living) environment in order to foster and encourage inclusion, safety, wellness, health and sustainability”. The Lombardy Cluster is among the six founders of the National Cluster working on the same themes. Again, in 2014: Regione Lombardia<http://www.en.regione.lombardia.it > signed a memorandum of understanding with INAIL (National Institute for Insurance Against Workplace Accidents) and identified Lecco as the district where the research on behalf of victims of traumatic accidents and technopathics should take place. The following table and descriptions give an overview on the collaborative research projects the Living Lab partners have been working on as a network since 2004, with a focus on rehabilitation:

Project/activity >

Actor v

Hint@Lecco Spider@Lecco Regional Cluster “Technologies for the Living Environment”

Design4All

Think&Go Riprendo@Home

Ability

Univerlecco Lead Lead Lead Consultant

Consultant Consultant

IRCCS Medea Partner Partner Partner Consultant

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Membership Application: ENoLL 9th Wave

Lecco Innovation Living Lab Page 3 of 19

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

IRCCS INRCA Partner Partner Consultant PA Politecnico di Milano sede di Lecco

Partner Partner Partner Lead Partner

Rehabilitation Center “Villa Beretta”

Partner Partner Partner Consultant Consultant Consultant

CNR Partner Partner Partner Lead Partner Partners (3 CNR groups working together)

Hint@Lecco: The research project aimed at creating a network of excellence in basic and applied biomedical research. Started in 2004; Budget: 5 million €; Sponsored by Fondazione Cariplo <http://www.fondazionecariplo.it/en/index.html>. Spider@Lecco: A follow up to Hint@Lecco. A research project aimed at building a local ecosystem for rehabilitation to assist patient throughout the whole process in the Province of Lecco. Started in 2010; Budget: 4.5 million €; Sponsored by Fondazione Cariplo and Regione Lombardia. Regional Cluster “Technologies for the Living Environment”: Univerlecco becomes coordinator. Design4All: In the frame of the National Cluster “Technologies for the Living Environment”. A research, development and eduction project on software integration and complex human-machine interfaces in the field of designing for Ambient Assisted Living. Started in 2013; Budget: 10 million €; Sponsored by MIUR (Ministry of Education, University and Research). Think&Go: aims at transferring knowledge in health through expertise and generate technologic strategic approaches to rehabilitation. Funded in 2013, started in 2014; Budget: 4 million €; Sponsored by Fondazione Cariplo and Regione Lombardia. Riprendo@Home; Development of innovative technologic personalized platforms for post-ictus neuromotor rehabilitation, with a focus on the upper limb and the use in a domestic environment. Started in 2013; Budget: 2.5 million €; Sponsored by Regione Lombardia. Ability: Development of an integrated platform enabling the remote delivery and control of physical and cognitive rehabilitation, and self management. Funded, not yet started; Budget: 4 million €; Sponsored by Regione Lombardia in the frame of the Smart Cities programme.

4. Organisation The Lecco Innovation Living Lab is wider than the network working on the research projects. It consists of Univerlecco, the Lecco Chamber of Commerce, the Municipality of Lecco, Politecnico di Milano sede di Lecco, four CNR groups (CNR IBFM, IENI, IPCB, ITIA), IRCCS Medea, IRCCS INRCA, the Rehabilitation Center “Villa Beretta” and UILDM (Italian Union for the Fight against Muscular Dystrophies).

Univerlecco: < http://www.univerlecco.it/> A territorial association formed by Lecco Chamber of Commerce, Lecco Municipality, Province Council of Lecco, Business Associations and Trade Unions, a Scientific Institute of Medical Research and a hospital. UniverLecco aims at promoting research centers and high-level education in the territory, especially Politecnico di Milano and CNR (National Research Council). UniverLecco mission is also to facilitate the relationships between the business and the scientific sectors to foster their participation in research and support projects, and to promote the transfer of research results to companies and institutions. Vico Valassi: He is Chairman of Univerlecco and the Lecco Chamber of Commerce and sits in the boards of Politecnico di Milano and CNR. He has held positions of importance in the Chambers of Commerce System, Associations and Research Institutions. His is instrumental in promoting innovation, education, the development of human capital, research and the collaboration between research and business. Among the architects of the systemic approach that encourages interactions and collaboration between companies, research and technology for the competitiveness of the local economic fabric. Cristina De Capitani: mechanical engineer, adjunct professor at Politecnico di Milano since 2002, responsible of Healthcare Sector of MIP (Politecnico di Milano Business School) for 4 years. Currently responsible of Project Area in

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Membership Application: ENoLL 9th Wave

Lecco Innovation Living Lab Page 4 of 19

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

Univerlecco and Cluster Manager of Lombardy Regional Cluster “Technologies for the Living Environment”. Research and consulting activities are mainly focused on quality and innovation management, as on design and management of healthcare systems. Francesco Rezzonico: Accountant. He served as Director to the Financial, Economic, Accounting and Fiscal for the Como Chamber of Commerce until 2009. He is Management/Financial supervisor and auditor for Univerlecco and standing statutory auditor for several companies in the Provinces of Como and Lecco. Lecco Chamber of Commerce, with the particular contribution of Promotion and Local Development Office and Studies and Strategic Planning Office, with its Statistics and Observatories Unit <http://www.lc.camcom.gov.it> Vico Valassi: President of the Lecco Chamber of Commerce. Municipality of Lecco <http://www.comune.lecco.it/home.jhtml> Virginio Brivio: Mayor of Lecco since April, 1st, 2010. Graduated in Law. A public servant of the Welfare Service System in the Municipality of Valmadrera. From 1996 to 2004 he was Council member for the Welfare Services, Vocational education, Sport, Youth politics in the Province of Lecco. From 2004 to 2009 he was President of the Province of Lecco. IRCCS Medea <http://www.emedea.it/english_medea/, http://www.emedea.it>: The only Scientific Institute in Italy recognized for research and rehabilitation in childhood and adolescence. Our mission is to promote biomedical and health research in close association with clinical practice to test new rehabilitation techniques and improve existing ones. The wide network of centers belonging to Association La Nostra Famiglia is a good testing ground for quantitatively and qualitatively sound research, especially in rehabilitation. Gianluigi Reni: Electronic Engineer, Head of the Applied Technology Research Area at the Medea Institute. Author of many patents in the electrical medical devices field. As a consultant he directed the redesign of information systems at various regional hospitals. Monica Castelli: High school diploma in foreign languages – engaged for more than 10 years as responsible of Grant Office for the activities in the design and management of European funded projects, experience in the evaluation systen of the EU projects, experience in the organisation of meetings. Anna Carla Turconi: MD,PM&R, Functional Rehabilitation Unit Director; experience in clinical management; rehabilitation protocols; advanced high technology know-how; research trials coordinator. Villa Beretta <http://www.valduce.it/index.php/villa-beretta>: VALDUCE Hospital Division of Recovery and Rehabilitation “Villa Beretta” is an Italian reference centre for neuro-rehabilitation, gait analysis, telemedicine and robotics applied to neuro-motor impaired condition. The target of the Centre is the person with some kind of neuro-motor disease/disability. Franco Molteni: Medical Doctor (1981), Italy, Physiatrist (1984), Italy. General Director of VALDUCE Division of Recovery and Rehabilitation Villa Beretta (since 2004), Physical Rehabilitation chief coordinator (1991-2004), Physical Rehabilitation specialist (1985 – 1991). Research interest: telemedicine and rehabilitation, high tech devices for improving impaired conditions. Giovanna Palumbo: Sociologist (1974), Venezuela; MBA, Venezuela (1989); Master in International Healthcare Management, Economics and Policy, Italy (2002). Project Manager at Valduce Hospital since 2010. Consultant and Researcher of Valduce Hospital in healthcare service costs and quality (2001-2010). Research interests: healthcare services and cost/efficiency analysis, rehabilitation clinical paths, patients and caregivers perceived quality of life Mauro Rossini: Biomedical Engineer (1998), Consultant of the Gait & Movement Laboratory (from 1996). Researcher and consultant in Clinical Gait & Movement Analysis. Research interest: Telemedicine, clinical movement analysis, modelling and simulation, new technology application in rehabilitation. IRCCS INRCA <http://www.inrca.it>: A public Scientific Institute uniquely recognized in Italy in the area of Geriatrics and Gerontology with the mission of carrying out high-standard clinical and translational research in the areas of biomedical and health services in a context of highly specialised medical care. IRCCS INRCA operates on a multiregional basis in Italy having an interdisciplinary Scientific Technological Area and 4 hospitals located in 3 Italian Regions, including the institution based in Casatenovo (Lecco). Fabrizia Lattanzio: MD, PhD, MSc, Geriatrician, since 2008 is the Scientific Director of the Italian National Centre on Health and Science on Aging (INRCA). She has a long-standing experience in geriatric research projects in various setting, as Principal Investigator. She has over 130 publications indexed in Medline.

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Membership Application: ENoLL 9th Wave

Lecco Innovation Living Lab Page 5 of 19

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

Enrico Eugenio Guffanti: MD, Pulmonologist, since 2005 is the Department Director of the INRCA hospital of Casatenovo (Lecco). He has an extensive experience in Respiratory Medicine with specific reference to Geriatrics and Rehabilitation and involvement in research projects in various setting. Lorena Rossi: Electronic Engineering graduate. With a long experience in development and management of HIS (Health information system), since 2010 is chief of Laboratory of Bioinformatics, Bioengineering and Domotics of INRCA. Her main interest is in use of technologies, informatics and telematics for the assistance of elderly people. Politecnico di Milano <http://www.polimi.it/en, http://www.polo-lecco.polimi.it/en/>: The Politecnico di Milano is one of the most outstanding universities in Europe, ranked 28th in the world and 9th in Europe among technical universities, according to The QS World University Ranking – Engineering & Technology 2013. Founded in 1863, it is the largest school of architecture, design and engineering in Italy, with three main campuses located in Milan, the heart of fashion and design industries and the future venue of Expo 2015, and five more premises around the Lombardy region. Marco Bocciolone: Mechanical Engineer (1987); Full Professor in Applied Mechanics (biomedical engineering program) and Mechanical and Thermal Measurements <http://www.mecc.polimi.it/en/>; Vice Rector for Lecco Campus of Politecnico di Milano; research interests: biomechanical measurements and signal processing, experimental characterisation of mechanical systems, measurements of wind actions on structures, railway vehicle and sub-structure interaction, quality systems and accreditation. Manuela Ghielmetti: Born the 7th of April 1980, in 2004 obtained a degree in Foreign Languages and Mass Communication cum laude from Univeristà Cattolica del Sacro Cuore – Milan. Lecco Campus Manager of Politecnico di Milano since February 2013, she has been working also as responsible for Communication and Public Relation office of Lecco Campus since 2007. Politecnico di Milano Bioengineering DEIB <http://www.deib.polimi.it>: The research activities of the Bioengineering Section at DEIB are divided into four main lines, which reflect the different aspects of Biological and Health Technologies: “Biomimetics and micro-nano technologies”; “Technologies for functional evaluation and rehabilitation”; “Technologies for therapy”; “Physiological modeling, diagnostics, health systems and e-health”. These application research lines integrate several fields of expertise concerning data, signal and image processing, modeling, ICT, instrumentation technologies, motion capturing, robotics, biomechanics, fluidics, micro-technologies. Alessandra Pedrocchi: M.Sc. in electrical engineering, Ph.D. in bioengineering (Politecnico di Milano). Assistant Professor in tenure track where she teaches neuroengineering in the Master of Science in Bioengineering (June 2008 – present). Her research activities are carried at the NearLab < www.nearlab.polimi.it> in the field of biomechanics in motor control, neuroengineering and neurorehabilitation. Politecnico di Milano SensibiLab and LyPhe <http://www.sensibilab.lecco.polimi.it>: SensibiLab and LyPhe at the Design Dept. develop solutions at three levels: technology, with the creation of sensor systems and their pre-processing architecture for the non-intrusive measurement of bio-physiological parameters; methodology, developing methods and algorithms for processing, in experimental and non-conventional paradigms, the data arriving from the sensors; application, experimentation and services in clinical, rehabilitative and sports areas. Giuseppe Andreoni: Assistant professor and PhD in Biomedical Engineering at the Industrial Design Faculty and Department where he is coordinator of the Sensibilab (Biomedical Sensors and Systems Lab.) and of the LyPhE (Laboratory of Physical Ergonomics). His main research topics are: wearable sensors, ergonomics, rehabilitation and assistive technology. Costa Fiammetta: Research fellow and PhD in Industrial Design; she is involved in the activities of the Ergonomics & Design research team, part of Politecnico di Milano INDACO Department. More specifically, she focuses on user research methods applied to product, system and interior design. Politecnico di Milano – Department of Management Economics and Industrial Engineering (DIG) <http://www.dig.polimi.it>: Research at DIG has the challenging goal of contributing to the development and dissemination of knowledge, managerial and engineering paradigms, technologies and policies to answer key societal challenges. In particular, researchers involved in the Health Care Management research line carry out investigations and applied research dealing with organization, innovation, technology and safety issues of healthcare organizations and networks. A multi-specialty research approach, integrating different perspectives, different research methodologies and different experiences, is made possible, thanks to a diversified portfolio of competencies and well established collaborations with leading healthcare institutions in Italy and Europe.

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Lecco Innovation Living Lab Page 6 of 19

European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

Paolo Trucco: Associate Professor of Operations Risk Management. His major research area is Risk Management of complex socio-technical systems, with deep knowledge in Oil&Gas, Critical Infrastructure (energy and transport), Healthcare and the impact of smart technologies on these industries. He is advisor of the EC DG Home Affairs and of the Lombardy Critical Infrastructures Resilience PPP. Since 2004 he is also member of the Healthcare Risk Management Steering Committee of the Government of the Lombardy Region. CNR <http://www.cnr.it/sitocnr/Englishversion/Englishversion.html>: The National Research Council (CNR) is a public organization; its duty is to carry out, promote, spread, transfer and improve research activities in the main sectors of knowledge growth and of its applications for the scientific, technological, economic and social development of the Country. CNR IENI <http://old.ieni.cnr.it/index.php/it/sedi/lecco>: The Institute for Energetics and Interphases will provide at the LL disposal comprehensive equipment for materials synthesis and characterisation, possibilities of creating non-standard test benches for new devices, and rapid prototyping by ABS 3D printing. Francesca Passaretti: Graduated in Industrial Chemistry, her research interests cover metallurgy in general and in particular in the field of synthesis and characterization of Shape Memory Alloys. Since 2009 is responsible of Unit of Lecco of CNR-IENI. Simone Pittaccio: A biomedical engineer. His main current interests focus on the application of functional metallic materials (e.g. shape memory alloys) in Neuromuscular Rehabilitation and the design of biomedical devices. Elena Villa: Graduated in Physics, her field of activity is the investigation and microstructural characterization of SMA FeSMA and innovative alloys by thermal, mechanical and functional analysis. CNR ITIA <http://www.itia.cnr.it/en>: The Institute for Industrial Technologies focuses its competences on: microsystems, mechatronic, robotic, control, diagnosis, monitoring and new generation supervising systems, virtual design methods of products and processes and new organizational, management and business paradigms. Tullio Tolio: Director of ITIA since 2008. Full Professor of “Manufacturing and Production Systems”; Teaching activities include the courses of “Manufacturing”, “Integrated Production Systems” and "Reconfigurable Manufacturing Systems" at Politecnico di Milano (TU Milan), Faculty of System Engineering. Head of the course on “Management of Research” offered to all Ph.D. students of Politecnico di Milano (TU Milan). Lorenzo Molinari Tosatti: PhD in Engineering in Mechanics Application, senior researcher and manager of the research group IRAS - Intelligent and Autonomous Robot Systems and Factory of the Future. Experience: robotics, pHRSI, Control systems, parallel kinematics robot, robotics for healthcare. Marco Sacco: Senior researcher and manager of research group EVA - Virtual Manufacturing Environment. Experience: VR/AR applied to the life-cycle of the product/process/factory, 3D simulation, knowledge management. Claudia Redaelli: Degree in Foreign Languages (thesis about cross-cultural psychology) and a Master in IT for humanistic studies graduates, she has been responsible for dissemination and communication and a human factors specialist. CNR IBFM <http://www.ibfm.cnr.it>: The Institute of Molecular Bioimaging and Physiology will partecipate with its competencies in the following fields: Biomedical Engineering: biomedical signals/images processing methods, for the characterization of the physiopathological mechanisms related to a disease (neurological, cardiovascular, oncological), for monitoring disease progression/regression, for evaluation of treatment efficacy. Physical exercise: Characterization of cardiovascular, ventilatory and metabolic responses to the physical exercise in different environmental conditions; mechanical and energetical aspects of movement and locomotion in healthy and pathological subjects. Biology/biochemistry: quantitative immuno-enzymatic methods of the main biomarkers related to patho-physiological conditions; real time PCR analysis of the expression levels of the patho-physiological biomarkers. Giovanna Rizzo: Graduated in Electronic Engineering (Biomedical), senior researcher. Research interests: biomedical tomographic imaging, processing and analysis of biomedical signals and images, multimodal image registration. Mauro Marzorati: Graduated in Medicine, Board Certification in Sports Medicine. Research interests: cardiovascular, ventilatory and metabolic responses to exercise both in healthy subjects (athletes or sedentaries) and patients (heart transplant recipients, patients with metabolic myopathies). Alessandra Vezzoli: Graduated in biology, PhD in Human Physiology, researcher. Research interests: muscle bioenergetic and biochemichemistry, oxidative stress and free-radical determination.

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European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

CNR IPCB <www.dsctm.cnr.it>: The Institute for Polymers, Composites and Biomaterials will provide at the LL a comprehensive and multidisciplinary expertise in the design and preparation of advanced and innovative polymeric materials within the following international platforms: Sustainable Chemistry, Advanced Materials and Key Enabling Technologies and Nanomedicine. CNR-IPCB will also provide all the available facilities for the characterization of innovative materials. Luigi Ambrosio: Director of Chemical Science & Materials Technology Department, National Research Council of Italy. His research interests include design and characterisation of polymers and composites for medical applications and tissue engineering, rheology of biological fluids, structural properties of natural tissue, properties and processing of polymers and composites and nanostructures, hydrogels and biodegradable polymers. Cosimo Carfagna: Director of the IPCB-CNR. His main research activities include the development of functional polymeric materials and composite, the development of processes for improving the recycling of polymeric materials and the synthesis and chemical modification of polymers for textiles and other applications fields. Marino Lavorgna: Graduated in Industrial Chemistry, his main research activities include the development of both organic-inorganic hybrids and multifunctional materials by sol gel approach as well as the multiscale characterization of polymeric and composite materials. UILDM <http://www.uildm.org>: For the last fifty years, UILDM has been the reference point for people suffering from distrophies and other neuromuscular diseases. Founded August 1961 by Federico Milcovich, with the aim to promote scientific research and health information about progressive muscular distrophies and other neuromuscual pathologies through all means; promotre and foster social integration of people with disability. LILL has a light governance model in order to be more flexible and efficient. It has a Technical and Scientific Committee (TSC), formed by representatives coming from different partners. Through a constant interaction and understanding of its potential sponsors (Regione Lombardia, Fondazione Cariplo, EU), partners and actors, it provides the Chairman with insights, which will ultimately result in a strategy involving the whole partnership (scheme below, left). The Chairman, coordinating with the LL Manager, activates management and communication resources, as well as a Technical and Scientific Secretary (TSS). The Secretary works with the partners and other actors to create an effective connection and team and appoint an appropriate project leader. More generally, other resources (in blue) are activated only when needed (scheme below, right).

Univerlecco acts as a coordinator and catalyst throughout the whole process, offering strategic planning, managerial support, identifying research themes and goals, driving the dissemination. Moreover, it is a bridge between users, research and business. Politecnico di Milano sede di Lecco, CNR (IBFM, IENI, IPCB, ITIA), IRCCS INRCA, IRCCS Medea, Villa Beretta and UILDM offer expertise on identifying research themes and goals, writing projects, local, national and international networking and partnerships through their networks, carrying out research and developing prototypes. Additionally, IRCCS INRCA, IRCCS Medea and Villa Beretta are devoted to testing directly with patients and validating prototypes and experimental therapies through clinical trials. The Lecco Chamber of Commerce and the Municipality of Lecco have expertise in policymaking and problem-solving, knowledge in current legislation themes. Respectively, they support businesses and citizens.

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European Network of Living Labs AISBL, Pleinlaan 9, 1050 Brussels, Belgium www.openlivinglabs.eu [email protected]

LILL interaction: The Living Lab resources are activated selectively. On the one side users or institutions come (or are asked to come, whenever funding is available) with a question, a problem, a theme (input). Upon evaluation carried out by the Living Lab personnel and its partners, the most appropriate resources will be identified and the connection is

created on the industry and/or technical/scientific side. Alongside, to support the operations, additional management resources are called in to help with problem solving, budgeting, patenting and any help they may require to reach their goal (output). These output may be a systemic local or international research or R&D project, creating a product, service, etc.

5. Openness The idea of sharing resources and spaces, meeting and teaming up is one of the key elements to make the best use of what is available in Lecco. Already in 2007, Politecnico di Milano and CNR with the support of Univerlecco signed an agreement to share their research facilities in Politecnico di Milano Lecco Campus, where Politecnico di Milano has 14 research laboratories and CNR has a research hub hosting 7 CNR Institutes, inaugurated May 15th, 2015. In Think&Go, a research and education project started in April 2014, ten research grants were appointed to young researchers that are shared among the LL partners, to act as bridges and carriers. Another aim of the same project is mapping and indexing all of the available assets and expertise to facilitate the identification of the right resources and potentially attract foreign investors. Currently, IRP issues are addressed separately on each project. The experience on several ecosystemic projects focused on the development of products, services and platforms supplied valuable information for the debate on the development of shared policies in a complex environments that includes public and private partners and stakeholders, as well as research and enterprises. A first step can be seen in the inclusive approach of the network, validated by the partners. Anyone who has a proven interest in driving and supporting innovation is welcome to join, with a stress on helping and supporting SME, an important actor to generate socioeconomic value for the local area. The approach has been tested by the partnership working on neurorehabilitation and the Regional Cluster “Technologies for the Living Environment”. In particular, because of its nature and role, the Cluster acts an advocate and an interface with the Regional administration on the management and funds support needed for the development of themes that are relevant to the local actors on key areas. These experiments acted as a testbed and are a reference for future policies. To be more inclusive and maximise the potential of the network, new online resources have been and are being developed to complement old ones. A shared platform for the Living Lab partners provides basic information and support. Moreover, more complex services as a showcase of the available assets is currently being tested with the first prototypes, products and services already online on the Cluster website. – http://www.leccolivinglab.com, http://www.univerlecco.it, http://www.clustertav.lombardia.it.

6. Resources What is most essential is a flexible infrastructure, policies for coordination, and the knowledge of what is available for an effective matchmaking, in order to minimize costs and maximize opportunities. Within that framework, actors can work with different roles and responsibilities to ideate, develop and deliver research results, prototypes, products, services, etc. The most labour intensive and risky activities are management and laying out project proposals. These can be carried out by any partner of the Living Lab, as anyone has skills, experience and proven track record. Usually, the Univerlecco staff provides the basic support needed, and the number of people involved in the process varies greatly from project to project, depending on the need, will and restrictions.

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As described in section 4, part of this model is already self-sustained, the goal being becoming more self-sufficient through commissions and support for enterprises needing the Living Lab and funds coming from projects and sponsors. These revenues can be used to fuel the innovation process. In terms of international contacts, the partnership was born and has grown and strengthened at a local level, since that was a primary requirement to develop a long-term ecosystemic approach. In the meantime, individual institutions –especially Politecnico di Milano Lecco Campus and the four CNR groups,– and enterprises kept working also in international contexts on a number of projects and maintaining a high percentage in terms of products/services export. Recently, the partnership as a whole started to expand and work with international contacts. Relevant experiences include several members of the Lombardy Cluster Technologies for Living Environments collaborating with the EIP AHA on four work tables: A2 - Specific Action for Falls, B3 - Specific Action for Integrated Care, C2 -Specific Action for Indipendent Living and D4 - Specific Action for Age-friendly buildings, cities & environments, occasionally supporting the partnership by leading a specific task and collecting deliverables, as it is the case with D4.4. Moreover, in Think&Go (2014), the third action in the project concerns two high profiles researchers from Grenoble and the MIT coming to Lecco for an exchange and a training period for young researchers. Finally, SensibiLab in the Politecnico di Milano sede di Lecco is coordinating “Pegaso”, a European FP7 that involves CNR IBFM, another partner of LILL, in an international consortium of 17. The project aims at engaging teen-agers in the adoption of healthy lifestyles for the prevention of obesity and related co-morbidities. Following this trend, many new opportunities opened with the Horizon2020, COSME programme. Currently the partnership is striving to write its own policies to be able to activate single partners or small partnerships to team up with foreign institutions and enterprises to work on European projects. Formalising the common values and effort by becoming a Living Lab member of the ENoLL network is an important step in the process. On the ecosystemic innovation side, Univerlecco developed “Business to Research”, a project launched in March 2014 that has seen many of the Living Lab partners involved as promoters or participants to the local network. The goal is to create knowledge to facilitate the access of enterprises to research institutions, as to build a shared path for growth to ensure competitivity in both worlds through co-design. Nine years before, in 2005, the Formare Ingegneri Stranieri (training foreign engineers) project started. As of today, it counts over 1600 foreign students, most of them with full bursaries, graduated in Master’s in Engineering at Politecnico di Milano. In a long-term vision, they become “ambassadors of our territory” once back in their homelands or move to a different country. The success of the project is underlined by Politecnico starting international degrees at its main premise in Milan in 2015. The project has now evolved into Int-ARS – International Attraction for Researchers and Students (http://www.int-ars.com), aiming at enhancing the local capacity by attracting not only students but also researchers and young entrepreneurs and providing them with unique opportunities. Finally, there is “EcoSmartLand”, promoted by the Lecco Chamber of Commerce with a wide partnership. It is a strategic territorial project to take advantage of the 2015 Expo to build values that will last beyond the event. In this frame, Univerlecco coordinates the Lecco Innovation Lab. It involves all of LILL partners and projects to work on innovation and health and inclusion themes.

7. Users and Reality LILL acknowledges the need for end users to play an active role in the process and bring their point of view to the table. Most recently, Univerlecco organized, in collaboration with the LL partners, the 6th Italian Forum of Ambient Assisted Living (http://www.foritaal2015.com), that brought together all stakeholders in the innovation process, from user associations to researchers, for a three-days long debate on how to tackle the challenges at hand. More specificly, a wide range of points of view were expressed, from the conceptual to the technical, socio-cultural, managerial, risk-management, psychological, neurological, design, etc. The practical value of enabling technologies as well as the symbolic value they help people express, dramatically improving the quality of life and fostering inclusion, engagement and participation. Projects and solutions are developed alongside end users and validated by them through iterative testing, mostly at the premises’ of our clinical partners, and are developed by researchers working together with companies. The LL subscribes to the paradigm of a distributed health industry, making citizens “co-creators of their own health”, thus leading the way for further investigation of all living environments, and especially the home, as important contexts where health is produced and maintained and care is provided. To give a few examples, the living lab has actively collaborated to the development

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• of Gloreha, most notably with the expertise developed with SPIDER@Lecco, and directly collaborating on the THINK&GO project. This rehabilitation glove, produced by Idrogenet, is currently being improved thanks to the input and observations gathered with feedback from patients, in the product design and interface. Moreover, to provide clinitians and patients with a better understanding of the therapy performance both in real-time and for comparative analysis, further integration with another device (EEG headset), by ABMedica, is being developed.

• of an innovative business model for a wearable exoskeleton called ReWalk, part of the technologies used for SPIDER@Lecco. The approach consisted of a rehabilitation path that starts at the hospital, a lease period for evaluation and training at home, coupled with a teleconference schedule for remote assistance, to enable patients evaluate and decide for themselves before effectively buying the exoskeleton, to ease the acquisition process and spread out the economic effort.

• of the ABILITY project are currently developing a telerehabilitation system designed to maintain contact between clinician, neuro-psychologist and patient/caregiver, supporting users in therapy adherence by giving continuous feedback about their performance to all actors involved, thus empowering end users and exploring the possibility for a novel. A first prototype will be tested in May-June 2015 with patients.

• of the RIPRENDO@Home project, where researchers work to prototype low cost customized solutions for home rehabilitation, trying to balance clinical needs with end-users engagement through real time tracking of the performance; the development of an innovative orthosis, where personalized solutions were designed and implemented through continuous testing with end users (in-house patients at the Villa Beretta rehabilitation center) and collaboration with an experienced company working with carbon fibers;

8. Value As part of the Think&Go project (2013) and long-term strategy, the Living Lab is currently mapping all the assets and resources available to index them and make them available to their partners and users of the Living Lab, and to attract potential investors. Moreover, there is the need to fully understand to what extent the value generation within the Lab can be enhanced and shared, and how. This topic is part of the ongoing discussion mentioned in sections 5 and 7. Some of the laboratories already mapped include: Robotics, Robotics for Rehabilitation, Advanced Materials, Advanced 3D prototyping, Novel composite structure for disabled patients, Bioengineering, Neuroimaging, Muscular physiology, Signal processing, Virtual and Augmented reality, Ergonomics and Design, Health organisation and market analysis, Digital application, Human factors evaluation, Biomedical Engineering for the integration and analysis of multimodal biomedical images, Pathophysiology of the physical exercise, Biomechanics, Free radical determination, Analysis and processing of biomedical signals, images and data, Gait&Motion Analysis Lab, ICT & Management Observatories. The Living Lab partners produced significant advancements in the field of rehabilitation in terms of knowledge and prototypes. However, the most difficult part is still transferring what is found with research into everyday tools. The Living Lab supports almost every phase of the value chain and beyond, from generation to use. Nonetheless, a critical aspect in health related products, services and platforms is the certification that comes after the clinical trial, and that cannot be internalized. One of the important goals of the Living Lab will be creating strategic partnerships to bridge the gap between research and the industry also at a legislative level. This will raise the rate of products that go onto the market and speed up the process. The result will be lower costs for manufacturers and providers and, eventually, end-users.

9. Direction and Plans for the Future As underlined in sections 2, 5 and 6, all the actors in the value chain are already involved with the Living Lab. The challenge is developing strategies and policies for a shared model, in order to overcome critical points in partnering up different actors and bridging research and the industry. The most delicate aspects to deal with are the laying out of shared IRP and NDA policies; balancing them with openness and the need to develop shared tools and a shared language; validating at an operative level the sustainability of the Living Lab as a single interface for all the actors involved in the process; understanding and developing policies for international project that require no more than 3 entities coming from the same Country; overcoming the difficulties of achieving a certification through strategic partnerships.

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Annex I Letter(s) of recommendation

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Annex II Letter(s) of support

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Consiglio Nazionale delle Ricerche IL PRESIDENTE

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DearVico,

UNNERLECCO Via Tonale 28/30 23900 Lecco (LC) Italy

I would like to confirm our participation in the partnership of the Lecco Innovation Living Lab, a candidate to become a part ofENoLL in the 9th W ave.

CNR has been contributing to Lecco Innovation Living Lab since 2004, with strategie contributions on many different levels.

First, it supports capacity building through innovation in the Lecco district. Among others, CNR participated to HINT@Lecco (2004-2008), SPIDER@Lecco (2010-2014, www.riabilitaonline.it) and THINK&GO (2013-2016). Ali these projects aim at establishing and enhancing an ecosystem in the field of rehabilitation that can provide innovative solutions and methodologies and cater the end user with a complete system of care that involves researchers, entrepreneurs, two research hospitals, a rehabilitation centre, P A, end users.

Examples of the expertise involved in this effort compri se (but are not limited to) the fields of mechatronics, sensors, advanced materials, bioimaging, robotics, virtual reality, with the ultimate goal to expand the scope ofthe research and collaboration to other fields.

Secondly, it fosters the empowerment of the first user group (patients) through research and collaboration. As an example, three CNR Institutes are working on "RIPRENDO@Home" (www.riprendoathome.it, 2013-2015), a project that aims at empowering users through the development of low cost customizable solutions for rehabilitation at home. Moreover, one CNR Institute is the lead partner in "DESIGN4All" (www.d4all.eu, 2013-2016), focused on R&D and education in the field of Ambient Assisted Living, Adaptive interfaces, Human-machine interaction.

Third, it supports the promotion of the research results in terms of new patents, ultimately supporting new entrepreneurship (spin-off, start-up, etc).

Finally, it boosts the second user group ofthe Living Lab (entrepreneurs), helping to bridge the gap between research and industry. CNR is among the promoters of B2R@Lecco, a set of actions designed to bring researchers and entrepreneurs together for face-to-face meetings, to give researchers a deeper understanding of the local economie fabric, to find common areas of interest an d develop joint solutions.

Best regards,

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