melanie s. sanford

Melanie S. Sanford

Department of Chemistry University of Michigan Ann Arbor, MI 48109

Tel. (734) 615-0451 Fax (734) 647-4865 [email protected] Research Group: http://www.umich.edu/~mssgroup/

EDUCATION: Ph.D., Chemistry June 2001 California Institute of Technology, Pasadena, CA Thesis Title: Synthetic and Mechanistic Investigations of Ruthenium Olefin Metathesis Catalysts

B.S.; M.S. cum laude with Distinction in Chemistry June 1996 Yale University, New Haven, CT

CURRENT POSITION: University of Michigan, Ann Arbor, MI Moses Gomberg Distinguished University Professor of Chemistry September 2016 – present Arthur F. Thurnau Professor of Chemistry July 2011 – present

PREVIOUS POSITIONS: University of Michigan, Ann Arbor, MI Moses Gomberg Collegiate Professor of Chemistry January 2012 – Sept 2016 Professor of Chemistry September 2010 – June 2011 Associate Professor of Chemistry May 2007 – August 2010 William R. Roush Assistant Professor of Chemistry October 2006 – May 2007 Assistant Professor of Chemistry July 2003 – October 2006

Princeton University, Princeton, NJ

NIH NRSA Postdoctoral Fellow August 2001 – June 2003 Advisor: Professor John T. Groves

California Institute of Technology, Pasadena, CA Graduate Student August 1997 – July 2001 Advisor: Professor Robert H. Grubbs

Yale University, New Haven, CT Undergraduate Student September 1994 – June 1996 Advisor: Professor Robert H. Crabtree

Naval Research Laboratory, Washington, DC Summer Intern Summer 2003, 2004, 2005 Advisor: Dr. David W. Conrad

AWARDS: Honorary Doctorate, University of South Florida (2018); Blavatnik Award (2017); ACS Fellow (2016); Distinguished University Professor (2016); Elected Member, National Academy of Sciences (2016); Elected Fellow, American Academy of Arts and Sciences (2016); SABIC Young Catalysis Investigator Award (2015); OMCOS Award (2015); UM Faculty Recognition Award (2014); ACS Sierra Nevada Section: Distinguished Chemist Award (2013); Raymond and Beverly Sackler Prize in Chemistry (2013); Tetrahedron Young Investigator Award in Synthetic Chemistry (2013); ACS Ipatieff Prize (2013); Thieme-IUPAC Prize (2012); Moses Gomberg Collegiate Chair (2012); Paul N. Rylander Award (2012); Classical High School Distinguished Alumni Award (2012); MacArthur Foundation Fellowship (2011); Royal Society of Chemistry Fluorine Prize (2011); Fellow of American Association for Advancement of Science (2011); ACS Award in Pure Chemistry (2011); Arthur F. Thurnau Professorship (2011); National Fresenius Award (2010);

Melanie S. Sanford p. 2 AWARDS (CONT): John Dewey Award for Undergraduate Education (2010); LSA Excellence in Teaching Award (2010); BASF Catalysis Award (2009); ACS Arthur C. Cope Scholar Award (2008); Dupont Young Investigator Award (2007); Roche Excellence in Chemistry Award (2007); GlaxoSmithKline Chemistry Scholars Award (2006); Abbott Young Investigator Award (2006); Presidential Early Career Award for Scientists and Engineers (2006); AstraZeneca Excellence in Chemistry Award (2006); Research Corporation Cottrell Scholar Award (2006); Alfred P. Sloan Research Fellow (2006); National Science Foundation CAREER Award (2006); Bristol Myers Squibb “Freedom to Discover” Award (2006); Eli Lilly Grantee Award (2005); Amgen Young Investigator Award (2005); Boehringer Ingelheim New Investigator Award in Organic Synthesis (2005); Beckman Young Investigator Award (2004); Camille and Henry Dreyfus Foundation New Faculty Award (2003); NIH NRSA Postdoctoral Fellowship (2001); Herbert Newby McCoy Award for Graduate Research (2001); Arthur Fleischer Award for Undergraduate Research (1996); East Coast Athletic Conference Scholar-Athlete Award (1996); National Science Scholar (1993); NCAA Gymnastics Academic All-American (1993-1996)

EDITORIAL and EDITORIAL ADVISORY BOARDS:

Journal of the American Chemical Society (Associate Editor) 2014-present Accounts of Chemical Research (Advisory Board) 2014-present Asian Journal of Organic Chemistry (Advisory Board) 2012-present Advanced Synthesis and Catalysis (Advisory Board) 2011-present ACS Catalysis (Advisory Board) 2011-present Synthesis and Synlett (Advisory Board) 2009-present Tetrahedron/Tetrahedron Letters (Advisory Board) 2015-present

RESEARCH PUBLICATIONS

[*] represents independent publication; undergraduate co-authors are underlined *(179) Roy, P.; Bour, J. R.; Sanford, M. S. “Synthesis and Reactivity of Ni(II) and Ni(III) Aminoquinoline Complexes for C(sp3)–H Amination to form β-Lactams,” 2019, manuscript in preparation. *(178) Roberts, C. R.; Camasso, N. M.; Bowes, E. G.; Sanford, M. S. “Reactivity and Selectivity Towards C–C versus C–O Bond Formation at High Valent Nickel Alkyl Complexes,” 2019, manuscript submitted. *(177) Meucci, E. A.; Sanford, M. S. “Aryl–Fluoride Bond-Forming Reactions at Nickel(IV) Centers,” 2019, manuscript submitted. *(176) Lee, S. J.; Brooks, A. F.; Ichiishi, N.; Makaravage, K. J.; Mossine, A. V.; Sanford, M. S.; Scott, P. J. H. “C–H [18F]Fluorination of 8-Methylquinolines with Ag18F,” Chem. Commun. 2019, asap article. *(175) Ferguson, D. M.; Malapit, C. M.; Bour, J. R.; Sanford, M. S. “Palladium-Catalyzed Difluoromethylation of Aryl Chlorides and Bromides with TMSCF2H,” J. Org. Chem. 2019, in press. *(174) Lee, M.; Adams, A.; Cox, P. B.; Sanford, M. S. “Access to 3D Alicyclic Amine-Containing Fragments through Transannular C–H Arylation,” Synlett 2019, asap article. *(173) Melvin, P. R.; Ferguson, D. M.; Schimler, S. D.; Bland, D. C.; Sanford, M. S. “Room Temperature Deoxyfluorination of Benzaldehydes and α-Ketoesters with Sulfuryl Fluoride and Tetramethylammonium Fluoride,” Org. Lett. 2019, asap article. *(172) Lee, S. J.; Makaravage, K. J.; Brooks, A. F.; Sanford, M. S.; Scott, P. J. H. “Cu-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C–H Bonds with KF,” Angew. Chem. Int. Ed. 2019, asap article. *(171) Ferguson, D. M.; Bour, J. R.; Canty, A. J.; Kampf, J. W.; Sanford, M. S. “Aryl–CF3 Coupling from Phosphinoferrocene-Ligated Palladium(II) Complexes,” Organometallics 2019, asap article.

Melanie S. Sanford p. 3 *(170) Aguilera, E. Y.; Sanford, M. S. “Model Complexes for the Palladium-Catalyzed Transannular C–H Functionalization of Alicyclic Amines,” Organometallics 2019, 38, 138-142. *(169) Yang, L.; Brooks, A.; Makaravage, K.; Zhang, H.; Sanford, M. S.; Scott, P.; Shao, X. “Radiosynthesis of [11C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-mediated Cyanation,” ACS Med. Chem. Lett. 2018, 9, 1274-1279. *(168) Schimler, S. D.; Froese, R. D. J.; Bland, D. C.; Sanford, M. S. “Reactions of Arylsulfonate Electrophiles with NMe4F: Mechanistic Insight, Reactivity, and Scope,” J. Org. Chem. 2018, 83, 11178-11190. *(167) Mantell, M. A.; Kampf, J. W.; Sanford, M. S. “Improved Synthesis of [CpRRhCl2]2 Complexes,” Organometallics 2018, 37, 3240-3242. *(166) Malapit, C. A.; Bour, J. R.; Brigham, C. E.; Sanford, M. S. “Base-Free Nickel-Catalysed Suzuki-Miyaura Couplings of Carboxylic Acid Fluorides,” Nature 2018, 563, 100-104. *(165) Cabrera, P. J.; Lee, M.; Sanford, M. S. “Second Generation Palladium Catalyst System for Transannular C–H Functionalization of Azabicycloalkanes,” J. Am. Chem. Soc. 2018, 140, 5599-5606. *(164) Makaravage, K. J.; Shao, X.; Brooks, A. F.; Sanford, M. S.; Scott, P. J. H. “Copper(II) Mediated [11C]Cyanation of Arylboronic Acids and Aryl Stannanes,” Org. Lett. 2018, 20, 1530-1533. *(163) James, B. R.; Boissonnault, J. A.; Wong-Foy, A. G.; Matzger, A. J.; Sanford, M. S. “Structure Activity Relationships in Metal-Organic Framework Catalysts for the Synthesis of Propylene Carbonate from CO2 and Propylene Oxide,” RSC Adv. 2018, 8, 2132-2137. *(162) Shrestha, A.; Lee, M.; Dunn, A. L.; Sanford, M. S. “Palladium-Catalyzed C–H Bond Acetoxylation via Electrochemical Oxidation,” Org. Lett. 2018, 20, 204-207. *(161) Hendriks, K. H.; Robinson, S. G.; Braten, M. N.; Sevov, C. S.; Helms, B. A.; Sigman, M. S.; Minteer, S. D.; Sanford, M. S. “High Performance Oligomeric Catholytes for Effective Macromolecular Separation in Nonaqueous Redox Flow Batteries,” ACS Cent. Sci. 2018, 4, 189-196. *(160) Mossine, A.; Brooks, A.; Bernard-Gauthier, V.; Bailey, J.; Ichiishi, N.; Schirmacher, R.; Sanford, M. S.; Scott, P. J. H. “Synthesis of PET Radiotracers by Copper-Mediated 18F Radiofluoronation of Organoborons: Importance of Order of Addition and Copeting Protodeborylation,”J. Lab. Comp. Radiopharm. 2018, 61, 228-236. *(159) Ichiishi, N.; Malapit, C. A.; Wozniak, L.; Sanford, M. S. “Palladium and Nickel-Catalyzed Decarbonylative C–S Coupling to Convert Thioesters to Thioethers,” Org. Lett. 2018, 20, 44-47. *(158) Camasso, N. M.; Canty, A. J.; Ariafard, A.; Sanford, M. S. “Experimental and Computational Studies of High Valent Nickel and Palladium Complexes,” Organometallics, 2017, 36, 4382-4393. *(157) Sevov, C. S.; Hendriks, K. H.; Sanford, M. S. “A Low Potential Pyridinium Anolyte for Aqueous Redox Flow Batteries,” J. Phys. Chem. C 2017, 121, 24376-24380. *(156) Malapit, C. A.; Ichiishi, N.; Sanford, M. S. “Pd-Catalyzed Decarbonylative Cross-Couplings of Aroyl Chlorides,” Org. Lett. 2017, 19, 4142-4145. *(155) Hendriks, K. H.; Sevov, C. S.; Cook, M. E.; Sanford, M. S. “Multi-Electron Cycling of a Low Potential Anolyte in Inexpensive Alkalai Metal Electrolytes for Non-Aqueous Redox Flow Batteries,” ACS Energy Lett. 2017, 2, 2430-2435. *(154) McCammant, M. S.; Thompson, S.; Krska, S. W.; Scott, P. J. H.; Sanford, M. S. “Copper-Mediated C(sp2)–H Nucleophilic Radiofluorination of Electron Rich (Hetero)Arenes,” Org. Lett. 2017, 19, 3939-3942. *(153) Ferguson, D. M; Bour, J. R.; Canty, A. J.; Kampf, J. W.; Sanford, M. S. “Stoichiometric and Catalytic Aryl-Perfluoroalkyl Coupling at Tri-tert-butylphosphine Palladium(II) Complexes,” J. Am. Chem. Soc. 2017, 139, 11662-11665.

Melanie S. Sanford p. 4 *(152) Chong, E.; Kampf, J. W.; Ariaford, A.; Canty, A. J.; Sanford, M. S. “Oxidatively Induced C–H Activation at High Valent Nickel,” J. Am. Chem. Soc. 2017, 139, 6058-6061. *(151) Cismesia, M. A.; Ryan, S. J.; Bland, D. C.; Sanford, M. S. “Multiple Approaches to the in situ Generation of Anhydrous Tetraalkylammonium Salts for SNAr Fluorination Reactions,” J. Org. Chem. 2017, 82, 5020-5026. *(150) Bour, J. R.; Kariofillis, S.; Sanford, M. S. “Synthesis, Reactivity, and Catalytic Applications of Isolable (NHC)CuCHF2 Complexes,” Organometallics 2017, 36, 1220-1223. *(149) Canty, A. J.; Camasso, N. M.; Higgs, A. T.; Yates, B. F.; Sanford, M. S. “Computational Study of C(sp3)–O Bond Formation at a PdIV Center,” Dalton Trans. 2017, 46, 3742-3748. *(148) Sevov, C. S.; Hickey, D. P.; Cook, M. E.; Robinson, S. G.; Barnett, S.; Minteer, S. D.; Sigman, M. S.; Sanford, M. S. “A Physical Organic Approach to Persistent, Cyclable, Low-Potential Electrolytes for Flow Battery Applications,” J. Am. Chem. Soc. 2017, 139, 2924-2927. *(147) Mossine, A. V.; Brooks, A. F.; Ichiishi, N.; Makavarage, K. J.; Sanford, M. S.; Scott, P. J. H. “Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Transition Metal Mediated Late-Stage Radiofluorination,” Sci. Rep. 2017, 7, 233. *(146) Schimler, S. D.; Cismesia, M. A.; Hanley, P. S.; Froese, R. D.; Jansma, M. J.; Bland, D. C.; Sanford, M. S. “Nucleophilic Deoxyfluorination of Phenols via Arylfluorosulfonate Intermediates,” J. Am. Chem. Soc. 2017, 139, 1452-1455. *(145) Lee, M. L.; Sanford, M. S. “Remote C(sp3)–H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate,” Org. Lett. 2017, 19, 572-575. *(144) Lotz, M. D.; Camasso, N. M.; Canty, A. J.; Sanford, M. S. “Role of Silver Salts in Palladium-Catalyzed Arene and Heteroarene C–H Activation,” Organometallics 2017, 36, 165-171. *(143) Meucci, E. A.; Camasso, N. M.; Sanford, M. S. “An Organometallic NiIV Complex that Participates in Competing Transmetallation and C(sp2)–O Bond-Forming Reductive Elimination Reactions,” Organometallics 2017, 36, 247-250. *(142) Sevov, C. S.; Samaroo, S. K.; Sanford, M. S. “Cyclopropenium Salts as Cyclable High Potential Catholytes in Non-Aqueous Media,” Adv. Energy Mat. 2017, 7, 1602027. *(141) Makaravage, K. J.; Brooks, A. F.; Mossine, A. V.; Sanford, M. S.; Scott, P. J. H. “Copper-Mediated Radiofluorination of Aryl Stannanes,” Org. Lett. 2016, 18, 5440-5443. *(140) Sevov, C. S.; Fisher, S. L.; Thompson, L. T.; Sanford, M. S. “Mechanism-Based Development of a Low Potential, Soluble, and Cyclable Multi-Electron Anolyte for Non-Aqueous Redox Flow Batteries,” J. Am. Chem. Soc. 2016, 138, 15378-15384. *(139) Bour, J. R.; Camasso, N. M.; Meucci, E.; Kampf, J. W.; Canty, A. J.; Sanford, M. S. “Carbon-Carbon Bond Forming Reductive Elimination from Isolated Nickel(III) Complexes,” J. Am. Chem. Soc. 2016, 138, 16105-16111. *(138) Mbofana, C. T.; Chong. E.; Lawniczak, J.; Sanford, M. S. “Iron-Catalyzed Selective Oxyfunctionalization of Aliphatic Amines at Remote Benzylic Sites,” Org. Lett. 2016, 18, 4258-4261. *(137) Rezayee, N. M.; Samblanet, D. M.; Sanford, M. S. “Iron-Catalyzed Hydrogenation of Amides to Alcohols and Amines,” ACS Catal. 2016, 6, 6377-6383. *(136) Schimler, S. D.; Sanford, M. S. “Copper-Mediated Functionalization of Aryltrifluoroborates,” Synlett 2016, 27, 2279-2284.

Melanie S. Sanford p. 5 *(135) Pendleton, I. M.; Perez-Temprano, M. H.; Sanford, M. S.; Zimmerman, P. M. “Experimental and Computational Assessment of Reactivity and Mechanism in C(sp3)−N Bond-Forming Reductive Elimination from Palladium(IV),” J. Am. Chem. Soc. 2016, 138, 6049-6060. *(134) Genna, D. G.; Pfund, L. Y.; Samblanet, D. C.; Wong-Foy, A. G.; Matzger, A. J.; Sanford, M. S. “Rhodium Hydrogenation Catalysts Supported in Metal Organic Frameworks: Influence of the Framework on Catalytic Activity and Selectivity,” ACS Catal. 2016, 6, 3569-3574. *(133) Sanford, M.; Scott, P. “Moving Metal-Mediated 18F-Fluorination from Concept to Clinic,” ACS Central Sci. 2016, 2, 128-130. *(132) Brewster, T. P.; Rezayee, N. M.; Culakova, Z.; Sanford, M. S.; Goldberg, K. I. “Base-Free Iridium-Catalyzed Hydrogenation of Esters and Lactones,” ACS Catal. 2016, 6, 3113-3116. *(131) Cook, A. K.; Schimler, S. D.; Matzger, A. J.; Sanford, M. S. “Catalyst-Controlled Selectivity in the C–H Borylation of Methane and Ethane,” Science 2016, 351, 1421-1424. *(130) Topczewski, J. J.; Cabrera, P. J.; Saper, N. I.; Sanford, M. S. “Palladium-Catalysed Transannular C–H Functionalisation of Alicyclic Amines,” Nature 2016, 531, 220-224. *(129) Schimler, S. D.; Ryan, S. J.; Bland, D. C.; Anderson, J. E.; Sanford, M. S. “Anhydrous Tetramethylammonium Fluoride for Room Temperature SNAr Fluorination,” J. Org. Chem. 2015, 80, 12137-12145. *(128) Mossine, A. V.; Brooks, A. F.; Makavarage, K.; Miller, J.; Ichiishi, N.; Sanford, M. S.; Scott, P. J. H. “Synthesis of [18F]Arenes via the Cu-Mediated [18F]Fluorination of Boronic Acids,” Org. Lett. 2015, 17, 5780-5783. *(127) Cabrera, P. J.; Yang, X.; Suttil, J. A.; Brooner, R. E. M.; Thompson, L. T.; Sanford, M. S. “Evaluation of Tris-Bipyridine Chromium Complexes for Flow Battery Applications: Impact of Bipyridine Ligand Structure on Solubility and Electrochemistry,” Inorg. Chem. 2015, 54, 10214-10223. *(126) Sevov, C. S.; Brooner, R. E. M.; Chénard, E.; Assary, R. S.; Moore, J. S.; Rodriguez-Lopez, J.; Sanford, M. S. “Evolutionary Design of Low Molecular Weight Organic Anolyte Materials for Applications in Non-Aqueous Redox Flow Batteries,” J. Am. Chem. Soc. 2015, 137, 14465-14472. *(125) Lee, M.; Sanford, M. S. “Platinum Catalyzed Terminal-Selective C(sp3)–H Oxidation of Aliphatic Amines,” J. Am. Chem. Soc. 2015, 137, 12796-12799. *(124) Bour, J. R.; Camasso, N. M.; Sanford, M. S. “Oxidation of Ni(II) to Ni(IV) with Aryl Electrophiles Enables Ni(IV)-Mediated Aryl–CF3 Coupling,” J. Am. Chem. Soc. 2015, 137, 8034-8037. *(123) Cabrera, P. J.; Yang, X.; Suttil, J. A.; Hawthorne, K. L.; Brooner, R. E. M.; Sanford, M. S.; Thompson, L. T. “Chromium Complexes Containing Redox Non-Innocent Ligands for Symmetric, Multi-Electron Transfer Non-Aqueous Redox Flow Batteries,” J. Phys. Chem. C 2015, 119, 15882-15889. *(122) Ryan, S.; Schindler, S. D.; Bland, D. C.; Sanford, M. S. “Acyl Azolium Fluorides for Room Temperature Halex Fluorination of Chloro- and Nitroarenes,” Org. Lett. 2015, 17, 1866-1869. *(121) Canty, A. J.; Ariaford, A.; Yates, B. F.; Sanford, M. S. “Computational Study of Intramolecular Arene Palladation at a Palladium(IV) Center,” Organometallics 2015, 34, 1085-1090. *(120) Cook, A. K.; Sanford, M. S. “On the Mechanism of the Palladium-Catalyzed Acetoxylation of C–H Bonds: A Comparison of Catalyst and Ligand Effects,” J. Am. Chem. Soc. 2015, 137, 3109-3118 *(119) Camasso, N. M.; Sanford, M. S. “Design, Synthesis, and Carbon-Heteroatom Coupling Reactions of Organometallic Nickel(IV) Complexes,” Science 2015, 347, 1218-1220.

Melanie S. Sanford p. 6 *(118) Rezayee, N. M.; Huff, C. A.; Sanford, M. S. “Tandem Amine and Ru Catalyzed Hydrogenation of CO2 to Methanol,” J. Am. Chem. Soc. 2015, 137, 1028-1031. *(117) Suttil, J. A.; Kucharyson, J. F.; Escalante-Garcia, I.; Cabrera, P. J.; James, B.; Savinell, R. F.; Sanford, M. S.; Thompson, L. T. “Metal Acetylacetonate Complexes for High Energy Density Non-Aqueous Redox Flow Batteries,” J. Mater. Chem. A 2015, 3, 7929-7938. *(116) Topczewski, J. J.; Sanford, M. S. “Carbon-Hydrogen (C–H) Activation at PdIV: A Frontier in C–H Functionalization,” Chem. Sci. 2015, 6, 70-76. *(115) Brooks, A. F.; Topczewski, J. J.; Ichiishi, N.; Sanford, M. S.; Scott, P. J. H. “Late Stage [18F]Fluorination: New Solutions to Old Problems,” Chem. Sci. 2014, 5, 4545-4553. *(114) Ichiishi, N.; Canty, A. J.; Yates, B. F.; Sanford, M. S. “Mechanistic Investigations of Cu-Catalyzed Fluorination of Diaryliodonium Salts: Elaborating the CuI/CuIII Manifold for Copper Catalysis,” Organometallics 2014, 33, 5525-5534. *(113) Camasso, N.; Perez-Temprano, M. H.; Sanford, M. S. “C(sp3)–O Bond-Forming Reductive Elimination from Pd(IV) with Diverse Oxygen Nucleophiles,” J. Am. Chem. Soc. 2014, 136, 12771-12775. *(112) Maleckis, A.; Sanford, M. S. “Synthesis of Fluoroalkyl Palladium and Nickel Complexes via Decarbonylation of Acylmetal Species,” Organometallics 2014, 33, 3831-3839. *(111) Allen, L. J.; Lee, S. H.; Cheng, Y.; Hanley, P.; Muhuhi, J.; Kane, E.; Powers, S.; Anderson, J.; Bell, B.; Roth, G.; Sanford, M. S.; Bland, D. C. “Developing Efficient Nucleophilic Fluorination Methods and Application to Substituted Picolinate Esters,” Org. Proc. Res. Dev. 2014, 18, 1045-1054. *(110) Ichiishi, N.; Brooks, A. F.; Topczewski, J. J.; Rodnick, M.; Sanford, M. S.; Scott, P. H “Cu-Catalyzed High Specific Activity [18F]Fluorination of (Mesityl)(Aryl)Iodonium Salts with K[18F]F,” Org. Lett. 2014, 16, 3224-3227. *(109) Maleckis, A.; Sanford, M. S. “A Catalytic Cycle for Pd-Catalyzed Trifluoromethylation using Trifluoroacetic Esters as a CF3 Source,” Organometallics 2014, 33, 2653-2660. *(108) Allen, L. J.; Muhuhi, J. M.; Bland, D. C.; Merzel, R.; Sanford, M. S. “Room Temperature Fluorination of meta-Chloropyridines with in situ Generated Anhydrous Tetrabutylammonium Fluoride,” J. Org. Chem. 2014, 79, 5827-5833. *(107) Lotz, M. D.; Remy, M. S.; Lao, D. B.; Canty, A. J.; Mayer, J. M.; Sanford, M. S. “Formation of Ethane from Mono-Methyl Palladium(II) Complexes,” J. Am. Chem. Soc. 2014, 136, 8237-8242. *(106) Wagner, A. M.; Sanford, M. S. “Transition Metal Free Acid Mediated Synthesis of Aryl Sulfides from Thiols or Thioethers,” J. Org. Chem. 2014, 79, 2263-2267 *(105) Allen, L. J.; Cabrera, P. J.; Lee, M.; Sanford, M. S. “Room Temperature C–H Amination of Arenes and Heteroarenes Using Visible Light Photoredox Catalysis,” J. Am. Chem. Soc. 2014, 136, 5607-5610. *(104) Perez-Temprano, M. H.; Racowski, J. M.; Kampf, J. W.; Sanford, M. S. “Competition Between sp3-C–N and sp3-C–F Reductive Elimination from Palladium(IV) Complexes,” J. Am. Chem. Soc. 2014, 136, 4097-4100. *(103) Cook, A. K.; Emmert, M. H.; Sanford, M. S. “Acridine as a Ligand for Controlling Site Selectivity in the Palladium-Catalyzed C–H Acetoxylation of Simple Arenes,” Org. Lett. 2013, 15, 5428-5431. *(102) Ye, Y.; Schimler, S. D.; Hanley, P. S.; Sanford, M. S. “Cu(OTf)2-Mediated Fluorination of Aryltrifluoroborates with Potassium Fluoride,” J. Am. Chem. Soc. 2013, 135, 16292-16295. *(101) Wagner, A. M.; Hickman, A. J.; Sanford, M. S. “Platinum Catalyzed C–H Arylation of Simple Arenes,” J. Am. Chem. Soc. 2013, 135, 15110-15113.

Melanie S. Sanford p. 7 *(100) Huff, C. A.; Sanford, M. S. “Hydrogenation of CO2 to Formate Catalyzed by a Ru Pincer Complex,” ACS Catal. 2013, 3, 2412-2416. *(99) Ichiishi, N.; Canty, A. J.; Yates, B. F.; Sanford, M. S. “Cu-Catalyzed Fluorination of Diaryliodonium Salts with KF,” Org. Lett. 2013, 15, 5134-5137. *(98) Lehman, M. C.; Gary, J. B.; Sanford, M. S.; Ison, E. A. “Effect of Solvent and Ligands on the Catalytic H/D Exchange Reactivity of CpIr(L) Complexes,” ACS Catal. 2013, 3, 2304-2310. *(97) Huff, C. A.; Kampf, J. W.; Sanford, M. S. “Reversible Carbon-Carbon Bond Formation Between Carbonyl Compounds and a Ruthenium Pincer Complex,” Chem. Commun. 2013, 49, 7147-7149. *(96) Seigerman, C. K.; Micyus, T. M.; Neufeldt, S. R.; Sanford, M. S. “Palladium-Catalyzed C–H Arylation Using Aryltrifluoroborates in Conjunction with a Mn(III) Oxidant Under Mild Conditions,” Tetrahedron 2013, 69, 5580-5587. *(95) Sanhueza, I.; Wagner, A. M.; Sanford, M. S.; Schoenebeck, F. “On the Role of Anionic Ligands in the Site Selectivity of Oxidative C–H Functionalization Reactions of Arenes,” Chem. Sci. 2013, 4, 2767-2775. *(94) Genna, D. T.; Wong-Foy, A. G.; Matzger, A. J.; Sanford, M. S. “Heterogenization of Homogeneous Catalysts in Metal Organic Frameworks via Cation Exchange,” J. Am. Chem. Soc. 2013, 135, 10586-10589. *(93) Maleckis, A.; Kampf, J. W.; Sanford, M. S. “Acetate-Assisted C–H Activation at Cationic Palladium(IV) Centers,” J. Am. Chem. Soc. 2013, 135, 6618-6625. *(92) Ye, Y.; Sanford, M. S. “Mild Copper-Mediated Fluorination of Aryl Stannanes and Aryl Trifluoroborates,” J. Am. Chem. Soc. 2013, 135, 4648-4651. *(91) Gary, J. B.; Cook, A. K.; Sanford, M. S. “Palladium Catalysts Containing Cationic Pyridine Ligands for the C–H Acetoxylation of Benzene with K2S2O8 as Oxidant,” ACS Catal. 2013, 3, 700-703. *(90) Neufeldt, S. R.; Seigerman, C. K.; Sanford, M. S. “Mild Palladium-Catalyzed C–H Alkylation Using Potassium Alkyltrifluoroborates in Combination with MnF3,” Org. Lett. 2013, 15, 2302-2305. *(89) Canty, A. J.; Ariaford, A.; Sanford, M. S.; Yates, B. F. “Mechanism of Pd-Catalyzed Ar–Ar Bond Formation involving Ligand-Directed C–H Arylation and Diaryliodonium Oxidants: Computational Studies of Orthopalladation at Binuclear Pd(II) Centers, Oxidation to form Binuclear Palladium(III) Species, and Ar···Ar Reductive Coupling,” Organometallics 2013, 32, 544-555. *(88) Neufeldt, S. R.; Sanford, M. S. “Asymmetric Chiral Ligand-Directed Alkene Dioxygenation,” Org. Lett. 2012, 15, 46-49. *(87) Ye, Y.; Künzi, S. A.; Sanford, M. S. “Practical Method For the Cu-Mediated Trifluoromethylation of Arylboronic Acids with CF3 Radicals Derived from NaSO2CF3/TBHP,” Org. Lett. 2012, 14, 4979-4981. *(86) Neufeldt, S. R.; Sanford, M. S. “Combining Transition Metal Catalysis with Radical Chemistry: Dramatic Acceleration of Pd-Catalyzed C–H Arylation with Diaryliodonium Salts,” Adv. Syn. Catal. 2012, 354, 3517-3522. *(85) McMurtrey, K. B.; Racowski, J. M.; Sanford, M. S. “Palladium-Catalyzed C–H Fluorination with Nucleophilic Fluoride,” Org. Lett. 2012, 14, 4094-4097. *(84) Ye, Y.; Sanford, M. S. “Investigations into Transition Metal Catalyzed Trifluoromethylation Reactions,” Synlett, 2012, 23, 2005-2013. *(83) Huff, C. A.; Kampf, J.; Sanford, M. S. “Role of a Non-Innocent Pincer Ligand in the Activation of CO2 at (NNP)Ru(H)(CO),” Organometallics 2012, 31, 4643-4645.

Melanie S. Sanford p. 8 *(82) Stowers, K. J.; Kubota, A.; Sanford, M. S. “Palladium/Nitrate-Catalyzed Oxidation of Unactivated sp3 C–H Bonds with Dioxygen as the Terminal Oxidant,” Chem. Sci. 2012, 3, 3192-3195. *(81) Powers, D. C.; Lee, E.; Ariafard, A.; Sanford, M. S.; Yates, B. F.; Canty, A. J.; Ritter, T. “Connecting Binuclear Pd(III) and Mononuclear Pd(IV) Chemistry by Pd–Pd Bond Cleavage,” J. Am. Chem. Soc. 2012, 134, 12002-12009. *(80) Ye, Y.; Sanford, M. S. “Merging Visible Light Photocatalysis and Transition Metal Catalysis in the Copper-Catalyzed Trifluoromethylation of Boronic Acids with CF3I,” J. Am. Chem. Soc. 2012, 134, 9034-9037. *(79) Gary, J. B.; Carter, T. J.; Sanford, M. S. “Rhodium(III) Pyridinium Substituted Complexes as Catalysts for H/D Exchange,” Top. Catal. 2012, 55, 565-570. *(78) Hickman, A. J.; Sanford, M. S. “High Valent Copper and Palladium in Catalysis,” Nature 2012, 484, 177-185. *(77) Neufeldt, S. R.; Sanford, M. S. “Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization,” Acc. Chem. Res. 2012, 45, 636-646. *(76) Kubota, A.; Emmert, M. H.; Sanford, M. S. “Pyridine Ligands as Promoters in PdII/0-Catalyzed C–H Olefination Reactions,” Org. Lett. 2012, 14, 1760-1763. *(75) Hickman, A. J.; Cismesia, M. A.; Sanford, M. S. “Structure-Activity Relationship Study of Diimine PtII Catalysts for H/D Exchange,” Organometallics 2012, 31, 1761-1766. *(74) Racowski, J. M.; Sanford, M. S. “sp3-Carbon-Fluorine Bond-Forming Reductive Elimination from Palladium(IV),” Angew. Chem. Int. Ed. 2012, 51, 3414-3417. *(73) Huff, C. A.; Sanford, M. S. “Cascade Catalysis for the Homogeneous Hydrogenation of Carbon Dioxide to Methanol,” J. Am. Chem. Soc. 2011, 133, 18122-18125. *(72) Park, T.-H.; Hickman, A. J.; Koh, K.; Martin, S.; Wong-Foy, A. G.; Sanford, M. S.; Matzger, A. J. “Highly Dispersed Palladium(II) in a Defective MOF: Application to C–H Activation and Functionalization,” J. Am. Chem. Soc. 2011, 133, 20138-20141. *(71) Kalyani, D.; McMurtrey, K. B.; Neufeldt, S. R.; Sanford, M. S. “Room Temperature C–H Arylation: Merger of Pd-Catalyzed C–H Functionalization and Visible Light Photocatalysis,” J. Am. Chem. Soc. 2011, 133, 18566-18569. *(70) Ye, Y.; Lee, S. H.; Sanford, M. S. “Silver-Mediated Trifluoromethylation of Arenes using TMSCF3,” Org. Lett. 2011, 13, 5464-5467. *(69) Gary, J. B.; Sanford, M. S. “Participation of Carbonyl Oxygen in Carbon–Carboxylate Bond-Forming Reductive Elimination from Palladium,” Organometallics 2011, 30, 6143-6149. *(68) Maleckis, A.; Sanford, M. S. “Facial Tridentate Ligands for Stabilizing Palladium(IV) Complexes,” Organometallics 2011, 30, 6617-6627. *(67) Racowski, J. M.; Ball, N. D.; Sanford, M. S. “C–H Bond Activation at Palladium(IV) Centers,” J. Am. Chem. Soc. 2011, 133, 18022-18025. *(66) Lanci, M. P.; Remy, M. S.; Lao, D. B.; Sanford, M. S.; Mayer, J. M. “Ligand Design in Trimethyl Platinum(IV) Diimine Complexes to Achieve C–C Bond-Forming Reductive Elimination,” Organometallics 2011, 30, 3704-3707.

Melanie S. Sanford p. 9 *(65) Emmert, M. H.; Cook, A. K.; Xie, Y. J.; Sanford, M. S. “Remarkably High Reactivity of Pd(OAc)2/Pyridine Catalysts for the Non-Directed C–H Oxygenation of Arenes,” Angew. Chem. Int. Ed. 2011, 50, 9409-9412. Featured on back cover. *(64) Kubota, A.; Sanford, M. S. “Palladium-Catalyzed Ligand-Directed Functionalization of Cyclopropanes,” Synthesis 2011, 2579-2589. *(63) Loy, R. N.; Sanford, M. S. “Palladium-Catalyzed C–H Perfluoroalkylation of Arenes,” Org. Lett. 2011, 13, 2548-2551. *(62) Ball, N. D.; Gary, J. B.; Ye, Y.; Kampf, J.; Sanford, M. S. “Mechanistic and Computational Studies of Aryl–CF3 Bond Formation from Pd(IV): Towards Room Temperature Aryl Trifluoromethylation,” J. Am. Chem. Soc. 2011, 133, 7577-7584. *(61) Stowers, K. J.; Fortner, K. C.; Sanford, M. S. “Aerobic Palladium-Catalyzed sp3 C–H Olefination: A Route to N-Heterocyclic Scaffolds and Alkenes,” J. Am. Chem. Soc. 2011, 133, 6541-6544. *(60) Satterfield, A. D.; Kubota, A.; Sanford, M. S. “Palladium-Catalyzed 1,1-Aryloxygenation of Terminal Olefins,” Org. Lett. 2011, 13, 1076-1079. *(59) Wagner, A. M.; Sanford, M. S. “Palladium-Catalyzed C–H Arylation of 2,5-Disubstituted Pyrroles,” Org. Lett. 2011, 13, 288-291. *(58) Lyons, T. W.; Hull, K. L.; Sanford M. S. “Controlling Site Selectivity in Palladium-Catalyzed C–H Oxidative Cross-Coupling,” J. Am. Chem. Soc. 2011, 133, 4455-4464. *(57) Hickman, A. J.; Sanford, M. S. “Catalyst Control of Site Selectivity in the PdII/IV-Catalyzed Direct Arylation of Naphthalene,” ACS Catal. 2011, 1, 170-174. *(56) Ye, Y.; Ball, N. D.; Kampf, J. W.; Sanford, M. S. “Oxidation of Catalytically Relevant Palladium Dimer with “CF3

+”: Formation and Reactivity of a Monomeric Palladium(IV) Aquo Product,” J. Am. Chem. Soc. 2010, 132, 14682-14687. *(55) Higgs, A. T.; Zinn, P. J.; Sanford, M. S. “Synthesis and Reactivity of (Phpy)2Ni (Phpy = 2-Phenylpyridine),” Organometallics 2010, 29, 5446-5449. *(54) Emmert, M. H.; Villalobos, J. M.; Gary, J. B.; Sanford, M. S. “Pt and Pd Complexes Containing Cationic Ligands as Catalysts for Arene H/D Exchange and Oxidation,” Angew. Chem. Int. Ed. 2010, 49, 5884-5886. *(53) Kalyani, D.; Satterfield, A. D.; Sanford, M. S. “Palladium-Catalyzed Oxidative Arylhalogenation of Alkenes: Synthetic Scope and Mechanistic Insights,” J. Am. Chem. Soc. 2010, 132, 8419-8427. *(52) Lyons, T. W.; Sanford, M. S. “Palladium-Catalyzed Ligand-Directed C–H Functionalization Reactions,” Chem. Rev. 2010, 110, 1147-1169. *(51) Ball, N. D.; Kampf, J. W.; Sanford, M. S. “Aryl-CF3 Bond-Forming Reductive Elimination from Palladium(IV),” J. Am. Chem. Soc. 2010, 132, 2878-2879. *(50) Remy, M. S.; Cundari, T.; Sanford, M. S. “Computational and Experimental Studies of Methyl Group Exchange Between Group 10 Metal Centers,” Organometallics 2010, 29, 1522-1525. *(49) Neufeldt, S. R.; Sanford, M. S. “O-Acetyl Oximes as Transformable Directing Groups for Pd-Catalyzed C–H Functionalization,” Org. Lett. 2010, 12, 532-535. *(48) Villalobos, J. M.; Hickman, A. J.; Sanford, M. S. “Platinum(II) Complexes Containing Quaternized Nitrogen Ligands: Synthesis, Stability, and Evaluation as Catalysts for Methane and Benzene H/D Exchange,” Organometallics 2010, 29, 257-262.

Melanie S. Sanford p. 10 *(47) Ball, N. D.; Kampf, J. W.; Sanford, M. S. “Synthesis and Reactivity of Palladium(II) Fluoride Complexes Containing Nitrogen Donor Ligands,” Dalton Trans. 2010, 39, 632-640. *(46) Higgs, A. T.; Zinn, P. J.; Simmons, S. J.; Sanford, M. S. “Oxidatively Induced Carbon-Halogen Bond-Forming Reactions at Nickel,” Organometallics 2009, 28, 6142-6144. *(45) Lanci, M. P.; Remy, M. S.; Kaminsky, W.; Mayer, J. M.; Sanford, M. S. “Oxidatively Induced Reductive Elimination from (tBu2bpy)Pd(Me)2: Palladium(IV) Intermediates in a One Electron Oxidation Reaction,” J. Am. Chem. Soc. 2009, 131, 15618-15620. *(44) Stowers, K. J.; Sanford, M. S. “Mechanistic Comparison Between Palladium-Catalyzed C–H Acetoxylation and C–H Chlorination,” Org. Lett. 2009, 11, 4584-4587. *(43) Arnold, P. L.; Sanford, M. S.; Pearson, S. M. “Chelating N-Heterocyclic Carbene-Alkoxide as a Supporting Ligand for PdII/IV C–H Bond Functionalization Catalysis,” J. Am. Chem. Soc. 2009, 131, 13912-13913. *(42) Hickman, A. J.; Villalobos, J. M.; Sanford, M. S. “A Quantitative Method to Assay Platinum Catalysts for Benzene H/D Exchange,” Organometallics 2009, 28, 5316-5322. *(41) Deprez, N. R.; Sanford, M. S. “Synthetic and Mechanistic Studies of Pd-Catalyzed C–H Arylation with Diaryliodonium Salts: Evidence for a Bimetallic High Oxidation State Pd Intermediate,” J. Am. Chem. Soc. 2009, 131, 11234-11241. *(40) Racowski, J. M.; Dick, A. R.; Sanford, M. S. “Detailed Study of C–O and C–C Bond-Forming Reductive Elimination from Stable C2N2O2 Palladium(IV) Complexes,” J. Am. Chem. Soc. 2009, 131, 10974-10983. *(39) Hull, K. L.; Sanford, M. S. “Mechanism of Benzoquinone-Promoted Palladium-Catalyzed Oxidative Cross Coupling Reactions,” J. Am. Chem. Soc. 2009, 131, 9651-9653. *(38) Ball, N. D.; Sanford, M. S. “Synthesis and Reactivity of a Mono-σ-Aryl Palladium(IV) Fluoride Complex,” J. Am. Chem. Soc. 2009, 131, 3796-3797. *(37) Lyons, T. W.; Sanford, M. S. “Pd(II/IV)-Catalyzed Cyclopropanation Reactions: Scope and Mechanism,” Tetrahedron 2009, 65, 3211-3221. *(36) Desai, L. V.; Stowers, K. J.; Sanford, M. S. “Insights into Directing Group Ability in Palladium-Catalyzed C–H Bond Functionalization,” J. Am. Chem. Soc. 2008, 130, 13285-13293. *(35) Whitfield, S. R.; Sanford, M. S. “Reactions of Platinum(II) Complexes with Chloride-Based Oxidants: Routes to Pt(IV) and Pt(III) Products,” Organometallics 2008, 27, 1683-1689. *(34) Kalyani, D.; Sanford, M. S. “Oxidatively Intercepting Heck Intermediates: Pd-Catalyzed 1,2- and 1,1- Arylhalogenation of Alkenes,” J. Am. Chem. Soc. 2008, 130, 2150-2151. *(33) Deprez, N. R.; Sanford, M. S. “Reactions of Hypervalent Iodine Reagents with Palladium: Mechanisms and Applications in Organic Synthesis,” Inorg. Chem. 2007, 46, 1924-1935. *(32) Whitfield, S. L.; Sanford, M. S. “Reactivity of Pd(II) Complexes with Electrophilic Chlorinating Reagents: Isolation of Pd(IV) Intermediates and Observation of C–Cl Bond-Forming Reductive Elimination,” J. Am. Chem. Soc. 2007, 129, 15142-15143. *(31) Hull, K. L.; Sanford, M. S. “Catalytic and Highly Regioselective Cross-Coupling of Aromatic C–H Substrates,” J. Am. Chem. Soc. 2007, 129, 11904-11905. *(30) Desai, L. V.; Sanford, M. S. “Construction of Tetrahydrofurans via Pd(II/IV)-Catalyzed Aminooxygenation of Alkenes,” Angew. Chem. Int. Ed. 2007, 46, 5737-5740.

Melanie S. Sanford p. 11 *(29) Welbes, L. L.; Lyons, T. W.; Cychosz, K. A.; Sanford, M. S. “Synthesis of Cyclopropanes via Pd(II/IV)-Catalyzed Reactions of Enynes,” J. Am. Chem. Soc. 2007, 129, 5836-5837. *(28) Dick, A. R.; Remy, M. S.; Kampf, J. W.; Sanford, M. S. “Carbon–Nitrogen Bond-Forming Reactions Between Palladacycles and Hypervalent Iodine Reagents,” Organometallics 2007, 26, 1365-1370. *(27) Dick, A. R.; Sanford, M. S. “Transition Metal Catalyzed Oxidative Functionalization of C–H Bonds,” Tetrahedron 2006, 62, 2439-2463. *(26) Hull, K. L.; Lanni, E. L.; Sanford, M. S. “Highly Regioselective Catalytic Oxidative Coupling Reactions: Synthetic Scope and Mechanistic Insights,” J. Am. Chem. Soc. 2006, 128, 14047-14049. *(25) Kalyani, D.; Dick, A. R.; Anani, W. Q.; Sanford, M. S. “Scope and Selectivity in Palladium-Catalyzed Directed C–H Bond Halogenation Reactions,” Tetrahedron 2006, 62, 11483-11498. *(24) Kalyani, D.; Dick, A. R.; Anani, W. Q.; Sanford, M. S. “A Simple Catalytic Method for the Regioselective Halogenation of Arenes,” Org. Lett. 2006, 8, 2523-2526. *(23) Hull, K. L.; Anani, W. Q.; Sanford, M. S. “Palladium-Catalyzed Fluorination of Carbon–Hydrogen Bonds,” J. Am. Chem. Soc. 2006, 128, 7134-7135. *(22) Deprez, N. R.; Kalyani, D.; Krause, A.; Sanford, M. S. “Room Temperature Palladium-Catalyzed 2-Arylation of Indoles,” J. Am. Chem. Soc. 2006, 128, 4972-4973. *(21) Desai, L. V.; Malik, H. A.; Sanford, M. S. “Oxone as an Inexpensive, Safe, and Environmentally Benign Oxidant for C–H Bond Oxygenation,” Org. Lett. 2006, 8, 1141-1145. (20) Han, Y. Z.; Sanford, M. S.; England, M. D.; Groves, J. T. “Mechanistic Studies of an Unusual Epoxide- Forming Elimination of a β-Hydroxyalkyl Rhodium Porphyrin,” Chem. Commun. 2006, 549-551. *(19) Kalberer, E. W.; Whitfield, S. R.; Sanford, M. S. “Application of Recyclable, Polymer-Immobilized Iodine(III) Oxidants in Catalytic C–H Bond Functionalization,” J. Mol. Catal. A 2006, 251, 108-113. *(18) Dick, A. R.; Kampf, J. W.; Sanford, M. S. “Unusually Stable Pd(IV) Complexes: Detailed Mechanistic Investigation of C–O Bond-Forming Reductive Elimination,” J. Am. Chem. Soc. 2005, 127, 12790-12791. *(17) Kalyani, D.; Sanford, M. S. “Regioselectivity in Palladium-Catalyzed C–H Activation/Oxygenation Reactions,” Org. Lett. 2005, 7, 4149-4152. *(16) Kalyani, D.; Deprez, N. R.; Desai, L. V.; Sanford, M. S. “Oxidative C–H Activation/C–C Bond Forming Reactions: Synthetic Scope and Mechanistic Insights,” J. Am. Chem. Soc. 2005, 127, 7330-7331. *(15) Dick, A. R.; Kampf, J. W.; Sanford, M. S. “Platinum Model Studies for Palladium-Catalyzed Oxidative Functionalization of C–H Bonds,” Organometallics 2005, 24, 482-485. *(14) Desai, L. V.; Hull, K. L.; Sanford, M. S. “Palladium-Catalyzed Oxygenation of Unactivated sp3 C–H Bonds,” J. Am. Chem. Soc. 2004, 126, 9542-9543. *(13) Dick, A. R.; Hull, K. L.; Sanford, M. S. “A Highly Selective Catalytic Method for the Oxidative Functionalization of C–H Bonds,” J. Am. Chem. Soc. 2004, 126, 2300-2301. (12) Sanford, M. S.; Groves, J. T. “Anti-Markovnikov Hydrofunctionalization of Olefins Mediated by Rhodium Porphyrins,” Angew. Chem., Int. Ed. 2004, 43, 588-590. (11) Love, J. A.; Sanford, M. S.; Henling, L. M.; Day, M. W.; Grubbs, R. H. “Synthesis, Structure, and Activity of Enhanced Initiators for Olefin Metathesis” J. Am. Chem. Soc. 2003, 125, 10103-10109.

Melanie S. Sanford p. 12 (10) Trnka, T. M.; Morgan, J. P.; Sanford, M. S.; Wilhelm, T. E.; Scholl, M.; Choi, T.-L.; Ding, S.; Day, M. W.; Grubbs, R. H. “Synthesis and Reactivity of Ruthenium Alkylidene Complexes Coordinated with Phosphine and N-Heterocyclic Carbene Ligands” J. Am. Chem. Soc. 2003, 125, 2546-2558. (9) Grubbs, R. H.; Trnka, T. M.; Sanford, M. S. “Transition Metal Carbene Complexes in Olefin Metathesis and Related Reactions,” Curr. Meth. Inorg. Chem. 2002, 3, 187-231. (8) Sanford, M. S.; Valdez, M. L.; Grubbs, R. H. “Reaction of TpRu(η2-O2CCHPh2)PPh3 with Carbene and Vinylidene Precursors,” Organometallics 2001, 20, 5455-5463. (7) Sanford, M. S.; Love, J. A.; Grubbs, R. H. “A Versatile Precursor for the Synthesis of Ruthenium Olefin Metathesis Catalysts,” Organometallics 2001, 20, 5314-5318. (6) Sanford, M. S.; Love, J. A.; Grubbs, R. H. “Mechanism and Activity of Ruthenium Olefin Metathesis Catalysts,” J. Am. Chem. Soc. 2001, 123, 6543-6554. (5) Sanford, M. S.; Ulman, M.; Grubbs, R. H. “New Insights into the Mechanism of Ruthenium Catalyzed Olefin Metathesis Reactions,” J. Am. Chem. Soc. 2001, 123, 749-750. (4) Sanford, M. S.; Henling L. M.; Day, M. W.; Grubbs, R. H. “Ruthenium-Based Four-Coordinate Olefin Metathesis Catalysts,” Angew. Chem., Int. Ed. 2000, 39, 3451-3454. (3) Sanford, M. S.; Henling, L. M.; Grubbs, R. H. “Synthesis and Reactivity of Neutral and Cationic Ruthenium(II) Tris(pyrazolyl)borate Alkylidenes,” Organometallics 1998, 17, 5384-5389. (2) Sanford, M. S.; Charles, P. T.; Commisso, S. M.; Roberts, J. C.; Conrad, D. W. “Photoactivatable Cross- Linked Polyacrylamide for the Site-Selective Immobilization of Antigens and Antibodies,” Chem. Mater. 1998, 10, 1510-1520. (1) Burdeniuc, J.; Sanford, M.; Crabtree, R. H. “Amine Charge Transfer Complexes of Perfluoroalkanes and an Application to Poly(tetrafluoroethylene) Surface Functionalization,” J. Fluor. Chem. 1998, 91, 49- 54.

Melanie S. Sanford p. 13

BOOK CHAPTERS:

*(7) Ichiishi, N.; Brooks, A. F.; Topczewski, J. J.; Rodnick, M. E.; Sanford, M. S.; Scott, P. J. H. “[18F]Fluorination of Mesityl)(Aryl)Iodonium Salts,” In Radiochemical Syntheses, Volume 2: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for their Production, 2015, 129-137. *(6) Cook, A. K.; Sanford, M. S. “C–H Halogenation,” In Science of Synthesis, 2015, 183-219. *(5) McMurtrey, K.; Sanford, M. S. “C–F Bond Formation,” In Science of Synthesis, 2012, 551-564. *(4) Racowski, J.; Sanford, M. S. “Carbon-Heteroatom Bond Forming Reductive Elimination from Palladium(IV) Complexes,” In Topics in Organometallic Chemistry, Vol. 53, Allan Canty, Ed., Springer, 2010, p. 61-84. *(3) Kalyani, D.; Sanford, M. S. “Chelate-Directed Oxidative Functionalization of Carbon–Hydrogen Bonds: Synthetic Applications and Mechanistic Insights,” In Topics in Organometallic Chemistry, Vol. 24, Naoto Chatani, Ed., Springer, 2007, 85-116. (2) Sanford, M. S.; Love, J. A. “Mechanism of Ruthenium-Catalyzed Olefin Metathesis Reactions,” In Handbook of Metathesis – Volume 1: Catalyst Development, Grubbs, R. H., Ed., Wiley-VCH, 2003, p. 112-131. (1) Grubbs, R. H.; Sanford, M. S. “Mechanism of Ruthenium Based Olefin Metathesis Catalysts,” In Ring Opening Metathesis Polymerization and Related Chemistry, E. Khosravi and T. Szymanska-Buzar, Eds., Kluwer Academic Publishers, 2002, p. 17-21. PATENTS (1) M. Sanford, S. Lee, L. Allen, Process for fluorinating compounds; Patent number: 9221757; 12/29/15 (Status: Granted) (2) L. Allen, M. Sanford, S. Lee, D. Bland, Y. Cheng, G. Roth, J. Muhuhi, Process for fluorinating compounds; Publication number: 20150141654; 5/21/15 (Status: Application) (3) M. Sanford, S. Lee, L. Allen, Process for fluorinating compounds; Publication number: 20150133673; 5/14/15 (Status: Application) (4) L. Allen, M. Sanford, D. Bland, Process for fluorinating compounds; Publication number: 20150133672; 5/14/15 (Status: Application) (5) P. J. H. Scott, A. F. Brooks, N. Ichiishi, M. S. Sanford, Preparation of Ag18F and its use in the synthesis of PET radiotracers; Publication number: 2016317682; 11/3/16 (Status: Application)

Melanie S. Sanford p. 14 INVITED PRESENTATIONS: 6/2004 NSF Workshop on Inorganic Chemistry, Sedona, AZ 8/2004 ACS National Meeting, Philadelphia, PA (Women in Organic Synthesis Symposium) 8/2004 Beckman Scholars Symposium, Irvine, CA 2/2005 Merck Research Laboratories, Process Chemistry, Rahway, NJ 3/2005 NSF Workshop on the Synthesis of Complex Chemical Systems, Boston, MA 3/2005 University of Connecticut, Storrs, CT (R. T. Major Lecture Series in honor of Robert H. Grubbs) 6/2005 Bristol Myers Squibb, Wallingford, CT 6/2005 Bristol Myers Squibb, Hopewell, NJ 6/2005 Eli Lilly, Indianapolis, IN 7/2005 Heterocyclic Compounds Gordon Research Conference, Newport, RI 7/2005 University of Konstanz, Konstanz, Germany 7/2005 ADHOC – International Conference on Homogeneous Catalytic Oxidation, Cologne, Germany 7/2005 RWTH Aachen University, Aachen, Germany 8/2005 Organic Reactions and Processes Gordon Research Conference, Smithfield, RI 8/2005 Beckman Scholars Symposium, Irvine, CA 9/2005 University of Kansas, Lawrence, KS 9/2005 Amgen, Thousand Oaks, CA (Amgen Young Investigator Award Symposium) 10/2005 Abbott Laboratories, Process Chemistry, Chicago, IL 11/2005 NSF Workshop on Sustainable Chemistry, Richland, WA 11/2005 Eastern Michigan University, Ypsilanti, MI 11/2005 Kenyon College, Gambier, OH 11/2005 Pomona College, Claremont, CA (Dreyfus Lecturer) 11/2005 Scripps Research Institute, La Jolla, CA 12/2005 Boehringer Ingelheim, Ridgefield, CT 12/2005 Pacifichem, Honolulu, HI (Synthesis and Mechanism in Late Transition Metal Organometallics) 12/2005 Pacifichem, Honolulu, HI (Activation of Unreactive Bonds in Organic Synthesis) 1/2006 University of Pittsburgh, Pittsburgh, PA (ACS PROGRESS Lecturer) 1/2006 University of North Carolina, Chapel Hill, NC 1/2006 Stanford University, Palo Alto, CA 1/2006 University of Pennsylvania, Philadelphia, PA 1/2006 GlaxoSmithKline, King of Prussia, PA 2/2006 Princeton University, Princeton, NJ 2/2006 Bryn Mawr College, Bryn Mawr, PA 2/2006 Dartmouth College, Hanover, NH 2/2006 University of Chicago, Chicago, IL 2/2006 University of Wisconsin, Madison, WI 2/2006 Brown University, Providence, RI 3/2006 Winter Conference on Medicinal and Bioorganic Chemistry, Clearwater Beach, FL 3/2006 University of Texas Southwestern Medical School, Dallas, TX 4/2006 DePauw University, Greencastle, IN (Burkett Lecturer) 4/2006 Harvard University, Cambridge, MA (Woodward Lecturer in the Chemical Sciences) 4/2006 Oberlin College, Oberlin, OH 4/2006 University of Missouri, Columbia, MO (Organic Chemistry Day Symposium) 5/2006 University of Washington, Seattle, WA 6/2006 Imperial College, London, UK (Eli Lilly Lecturer) 6/2006 Eli Lilly, Ascot, UK 6/2006 California Institute of Technology, Pasadena, CA 6/2006 Schering Plough Research Institute, Process Chemistry, Union, NJ 7/2006 Organometallics Gordon Conference, Newport, RI 7/2006 Professor Robert H. Grubbs Nobel Prize Symposium, Pasadena, CA 8/2006 Trans-Atlantic Frontiers in Chemistry Conference, Durham, NH 9/2006 Abbott Laboratories, Medicinal Chemistry, Chicago, IL

Melanie S. Sanford p. 15 9/2006 University of Southern California, Los Angeles, CA 10/2006 Johnson & Johnson Pharmaceutical R&D, San Diego, CA 10/2006 AstraZeneca Excellence in Chemistry Award Symposium 11/2006 Pfizer Global R&D, Groton, CT 11/2006 Smith College, North Hampton, MA (Rosenfeld Lecture in Organic Chemistry) 12/2006 Merck Research Laboratories, West Point, PA 1/2007 Yale University, New Haven, CT 1/2007 UC Berkeley, Berkeley, CA 1/2007 Boston University, Boston, MA (Novartis Lecturer) 2/2007 Macalester College, St Paul, MN 2/2007 University of Minnesota, Minneapolis, MN 2/2007 Inorganic Reaction Mechanisms Gordon Conference, Ventura, CA 3/2007 Emory University, Atlanta, GA 4/2007 ACS National Meeting, Chicago, IL (Symposium Honoring Professor Steven Ley for ACS Award) 4/2007 University of Toronto, Toronto, Canada (Pfizer Symposium) 5/2007 SUNY-Buffalo, Buffalo, NY 5/2007 Bristol Myers Squibb Excellence in Chemistry Symposium 5/2007 UC Irvine, Irvine, CA 6/2007 Roche Excellence in Chemistry Symposium, Nutley, NJ 6/2007 Heterocyclic Chemistry Gordon Conference 8/2007 OMCOS-14, Nara, Japan 9/2007 Abbott Symposium, Chicago, IL 9/2007 Columbia University, New York, NY 10/2007 University of Illinois, Urbana Champaign (RC Fuson Visiting Professor) 11/2007 Dow Chemical, Midland, MI 4/2008 MIT, Cambridge, MA (Organic Syntheses Lecturer) 6/2008 Pfizer, St. Louis, MO 7/2008 Stereochemistry Gordon Conference, Newport, RI 8/2008 ACS National Meeting, Cope Scholar Symposium, Philadelphia, PA 9/2008 GlaxoSmithKline Symposium, Chapel Hill, NC 10/2008 Calvin College, Grand Rapids, MI 12/2008 Boston College, Chestnut Hill, MA 1/2009 Sheffield Stereochemistry Conference, Sheffield, UK 2/2009 Michigan State University, East Lansing, MI 4/2009 Novartis, Cambridge, MA 4/2009 ACS/RSC/IUPAC Symposium, Cambridge, MA 5/2009 McGill University, Montreal, Canada (MethylGene Lecture) 5/2009 CERMACS Meeting, Cleveland, OH (Cope Scholar Symposium) 5/2009 Memorial Sloan Kettering Cancer Center, New York, NY 6/2009 National Organic Symposium, Boulder, CO (Plenary Lecturer) 6/2009 Physical Organic Chemistry Gordon Conference, Holderness, NH 9/2009 Michigan Green Chemistry Conference, Detroit, MI 10/2009 Princeton University, Princeton, NJ 10/2009 Welch Foundation Annual Meeting, Houston, TX 11/2009 Heidelberg Forum on Molecular Catalysis, Ruprecht-Karls-Universitaet, Heidelberg, Germany

1/2010 Cambridge University, Cambridge, UK (Eli Lilly Lecture) 1/2010 University of Edinburgh, Scotland, UK 2/2010 UCLA, Los Angeles, CA 3/2010 Eli Lilly Symposium, Indianapolis, IN 4/2010 Wayne State University, Detroit, MI (Organic Syntheses Lecture) 4/2010 Hope College, Holland, MI 5/2010 Stanford University, Palo Alto, CA (Distinguished Women in Science Speaker) 5/2010 University of Ottawa, Ottawa, Canada (Keith Fagnou Organic Symposium)

Melanie S. Sanford p. 16 6/2010 French American Chemical Society Meeting (FACS), Alcase, France 6/2010 Heterocyclic Compounds Gordon Conference, Newport, MA 8/2010 ACS National Meeting, Boston, MA (Symposium in honor of Keith Fagnou) 9/2010 Trinity University, San Antonio, TX 10/2010 University of Zurich, Zurich, Switzerland (Keynote Speaker in Dorothy Crowfoot-Hodgkin Symposium) 10/2010 Washington University, St Louis, MO 11/2010 Chicago Catalysis Club, Chicago, IL 11/2010 University of Virginia, Charlottesville, VA 12/2010 Pacifichem, Honolulu, Hawaii (Symposium on C-H Activation) 12/2010 Pacifichem, Honolulu, Hawaii (Symposium on Dioxygen Activation and Catalytic Oxidation Reactions)

1/2011 OZOM Conference, Hobart, Australia (Plenary Lecture in Symposium in Honor of Professor Allan Canty) 2/2011 University of Nebraska, Lincoln, NE (Charles A. Stiefvater Memorial Lecture) 3/2011 Queens University, Ontario, Canada 3/2011 ACS National Meeting, Anaheim, CA (Pure Chemistry Award Symposium) 3/2011 ACS National Meeting, Anaheim, CA (Fresenius Award Symposium) 4/2011 Eli Lilly Symposium, Madrid, Spain (Organic Synthesis in the International Year of Chemistry) 5/2011 Burgenstock Conference, Brunnen, Switzerland 5/2011 Harvard University, Cambridge, MA (Novartis Lecture) 5/2011 Merck, Boston, MA 5/2011 Frontiers in Catalysis Symposium in honor of Richard Heck, University of Delaware, Newark, DE 6/2011 Kent State University/Akron ACS Section, Akron, OH 7/2011 Organic Reactions and Processes Gordon Conference, Smithfield, RI 9/2011 RSC Fluorine Subgroup Postgraduate Meeting (Award Lecture), University of Aberdeen, Scotland, UK 10/2011 University of Cincinnati, Cincinnati, OH (Symposium in Honor of Professor Chuck Casey) 10/2011 Penn State University, College Park, PA 11/2011 Eastman Chemical, Kingsport, TN 11/2011 Merck, Kennilworth, NJ 11/2011 University of Michigan, Dearborn, MI 12/2011 Astra Zeneca, Boston, MA 1/2012 Scripps Research Institute, La Jolla, CA 1/2012 Yale University, New Haven, CT 1/2012 Torkil Holm Symposium "Visions in Chemistry" Symposium, Copenhagen, Denmark (Plenary Lecture) 2/2012 University of Wisconsin, Madison, WI (McElvain Lecturer) 3/2012 Canisius College, Buffalo, NY (Paul Gassman Memorial Lecture) 3/2012 University of Akron, Akron, OH 3/2012 ACS Akron Section, Akron, OH (Crano Lecture) 4/2012 Université Paris Sud, Paris, France (Rencontres en Chimie Organique) 4/2012 Organic Reactions Catalysis Society, Annapolis, MD (Rylander Award Lecture) 5/2012 Colorado State University, Ft Collins, CO (Innovator Lectureship) 6/2012 Organikerdagarna, Gothenburg, Sweden (Plenary Lecture) 7/2012 International Conference on Organic Synthesis, Melbourne, Australia (Plenary Lecture) 7/2012 ICIQ Summer School, Tarragona, Spain 8/2012 ACS National Meeting, Philadelphia, PA (50 Years of NIGMS-Supported Chemistry Research) 8/2012 ACS National Meeting, Philadelphia, PA (Symposium in honor of Alan Goldman) 9/2012 Takeda Science Foundation Symposium on PharmaSciences, Osaka, Japan (Plenary Lecturer) 10/2012 University of Northern Iowa (Leland Wilson Lectureship) 3/2013 Georgia Institute of Technology (Richard W. Fink Distinguished Lecturer), Atlanta, GA 4/2013 Novartis, San Francisco, CA 4/2013 Loyola University, Chicago, IL (Denkewalter Lecture) 4/2013 ACS National Meeting, New Orleans, LA (Ipatieff Award Symposium) 4/2013 ACS National Meeting, New Orleans, LA (ACS Graduate Student Symposium)

Melanie S. Sanford p. 17 4/2013 ACS National Meeting, New Orleans, LA (Symposium on Photoredox Catalysis) 4/2013 Vanderbilt University, Nashville, TN (Sigma Aldrich Lecturer) 4/2013 WPI, Worchester, MA 5/2013 Texas A&M University, College Station, TX 5/2013 UC Irvine, Irvine, CA (Irvine Organic Synthesis Lecturer) 6/2013 Sackler Prize Symposium, Tel Aviv, Israel (Sackler Prize Recipient Lecture) 6/2012 Tetrahedron Symposium, Vienna, Austria (Tetrahedron Young Investigator Award Lecture) 7/2013 Bayer, Berlin Germany 7/2013 UniCat Center of Excellence, Berlin, Germany 7/2013 TU Berlin, Berlin, Germany 8/2013 Novartis, Cambridge, MA 9/2013 Mt Holyoke College, South Hadley, MA (Lucy Pickett Lecturer) 9/2013 Amherst College, Amherst, MA 9/2013 UOP, Chicago, IL 9/2013 Northwestern University, Evanston, IL (Ipatieff Lecturer) 10/2013 Genentech, South San Francisco, CA 11/2013 University of Nevada, Reno 11/2013 Nevada ACS Section, Reno, NV (ACS Sierra Nevada Section Distinguished Chemist Award Lecture) 11/2013 University of Rochester, Rochester, NY (Magomedov-Shcherbinina Memorial Prize Lecture) 12/2013 Merck, Rahway, NJ 12/2013 University of Pennsylvania, Philadelphia, PA (Aldrich Lecturer) 2/2014 Caltech, Pasadena, CA (Novartis Lectureship) 3/2014 St Olaf College, Northfield, MN (Leraas Lecturer) 4/2014 Pfizer, Groton, CT 4/2014 MIT, Cambridge, MA (Pfizer Lecturer) 4/2014 Texas Tech University, Lubbock, TX (Shine Lecturer) 5/2014 University of Chicago, Chicago, IL (Closs Lecturer) 7/2014 Blavatnik Science Symposium, New York, NY 7/2014 Dow Chemical, Midland, MI 7/2014 DOE Catalysis Contractors Meeting, Annapolis, MD 10/2014 UNC, Chapel Hill, NC (Slayton Evans Lectureship) 10/2014 Pauling Medal Award Symposium in honor of Stephen Buchwald, Bellingham, WA 10/2014 University of Illinois, Urbana, IL (Frontiers in Organic Chemistry Symposium) 2/2015 UCLA, Los Angeles, CA (Amgen Lecturer) 3/2015 ACS National Meeting, Denver CO (Symposium in Honor or Maurice Brookhart) 3/2015 ACS National Meeting, Denver, CO (Symposium in Honor of Jay Groves) 5/2015 McGill University, Montreal, Canada (CGCC Lectureship) 5/2015 University of Montreal, Montreal, Canada (CGCC Lectureship) 5/2015 Princeton University, Princeton, NJ 6/2015 UM-ICIQ Symposium, Tarragona, Spain 6/2015 OMCOS-14, Sitges, Spain (OMCOS Award Lecturer) 7/2015 CENTC Summer School, Seattle, WA 8/2015 ACS National Meeting, Boston, MA (Symposium on Pharmaceutical Industry/Academic Collaborations) 8/2015 ACS National Meeting, Boston, MA (SABIC Award Symposium) 11/2015 University of Delaware, Newark, DE (Richard Heck Lecturer) 1/2016 UC Berkeley, Berkeley, CA (Heathcock Lecturer) 2/2016 University of Texas, Austin, TX (Vista Lecturer) 2/2016 Auburn University, Auburn, AL (Schneller Frontiers Lecturer) 3/2016 ACS National Meeting, San Diego, CA (Dreyfus/Presidential Symposium on: Making Molecules and

Materials) 3/2016 ACS National Meeting, San Diego, CA (Symposium in Honor of Karen Goldberg) 7/2016 Organic Reactions and Processes Gordon Research Conference, Smithfield, RI 8/2016 ACS National Meeting, Philadelphia (Symposium on New Trends in Organometallic Chemistry Leading to

Organic Synthesis)

Melanie S. Sanford p. 18 10/2016 Solvay Conference on Catalysis in Chemistry and Biology, Brussels, Belgium 2/2017 Scripps, La Jolla, CA (Frontiers Symposium) 3/2017 University of Utah, Salt Lake City, UT (Henry Eyring and Bryant Miner Endowed Lectureship) 4/2017 ACS National Meeting, San Francisco, CA (Presidential Symposium) 4/2017 ACS National Meeting, San Francisco, CA (Symposium in Honor of Matt Sigman) 4/2017 ACS National Meeting, San Francisco, CA (Symposium on Advances in Organic Synthesis: Successes

from Academia-Industry Partnerships) 5/2017 Oxford University, Oxford, UK (Andy Derome Lecture) 7/2017 Organometallic Chemistry Gordon Research Conference, Newport, RI 8/2017 ACS National Meeting, Washington, DC (CENTC Symposium) 8/2017 ACS National Meeting, Washington, DC (Symposium in Honor of Alex Miller) 12/2017 University of Bristol, Bristol, UK (Syngenta Lectureship) 12/2017 Syngenta, London, UK 3/2018 Montana State University, Bozeman, MT (Grieco Distinguished Lecturer) 3/2018 University of South Florida, Tampa, FL (Martin Lecturer) 7/2018 International Symposium on Fluorine Chemistry, Oxford, UK (Plenary Lecture) 7/2018 DOE, Catalysis Research PI Meeting, Gaithersburg, MD 10/2018 Caltech, Pasadena, CA (Beckman Lecturer) 12/2018 Columbia University, New York, NY (Gilbert Stork Lecturer) 3/2019 University of Minnesota, Minneapolis, MN (Gassman Lecturer) 3/2019 Grand Valley State University, Allendale, MI (Ott Lecturer) 4/2019 Yale University, New Haven, CT (Berson Lecturer) 5/2019 University of Washington, Seattle, WA (Cady Lecturer) 9/2019 University of Kentucky, Lexington, KY (Dawson Lecturer) 6/2020 Durham University, Durham, UK (Durham Lectures)

Melanie S. Sanford p. 19 CURRENT RESEARCH SUPPORT: Role: co-PI with Peter Scott (UM Radiology) Source: National Institutes of Health (R01EB021155) Title: Copper-mediated Late-Stage Radiofluorination of Electron-rich Arenes Dates of Project: 9/2016-3/2020 Amount: $1,386,266.00 (total costs) Role: PI Source: National Institutes of Health (1R01GM073836) Title: C–H Bond Functionalization in Organic Synthesis Dates of Project: 4/2016-3/2020 Amount: $1,101,064 (total costs) Role: PI Source: Department of Energy (DE-FG02-08ER15997) Title: MOF-Supported Metal Catalysts for Alkene Hydrogenation and C–H Functionalization Dates of Project: 8/15/2015-8/14/2018 Amount: $550,000 (total costs) Role: PI Source: Dow Chemical Title: Alternate Routes to Aniline and Phosgene Free Isocyanates Dates of Project: 5/2017-5/2022 Amount: $2,000,000 (total costs) Role: co-PI (PI = George Crabtree) Source: Department of Energy Title: JCSER (Joint Center for Energy Storage Research) Sub-contract: Flow Battery Active Species Derived from Metal Complexes Containing Non-Innocent Redox Active Ligands Dates of Project: 4/2012-3/2018 Amount to Sanford group: $661,748 (total costs) Role: PI Source: Dow Agrosciences Title: New Methods for Fluorination of Organic Molecules Dates of Project: 3/2018-3/2021 Amount: $300,000 (total costs) Role: co-PI (PI = Troels Skrydstrup) Source: Danish National Science Foundation Title: Carbon Dioxide Activation Center Dates of Project: 4/2015-3/2021 Amount to Sanford group: $484,162 (total costs) Role: PI Source: National Science Foundation (CHE-1664961) Title: Organometallic Chemistry of High Valent Nickel Dates of Project: 8/2017-7/2020 Amount: $449,988 (total costs)

Melanie S. Sanford p. 20 RESEARCH GROUP:

Current Members

Dr. Tom Vaid assistant research scientist 7/17-present

Dr. Courtney Roberts post-doctoral fellow 9/16-present Dr. Christian Malapit post-doctoral fellow 7/16-present

Dr. Patrick Melvin post-doctoral fellow 7/17-present

Dr. Tolani Kuam Salvador post-doctoral fellow 7/17-present

Dr. Yiyang See post-doctoral fellow 9/18-present

Dr. Scott Thullen post-doctoral fellow 9/18-present Dr. Liam Sharninghausen post-doctoral fellow 9/18-present

Devin Ferguson 5th year organic student 1/15-present

Katarina Makaravage 5th year organic student 1/15-present

Mark Mantell 4th year inorganic student 5/16-present

Monique Cook 4th year materials student 5/16-present Rackham Merit Fellowship

Liz Meucci 4th year organic student 5/16-present Rackham Merit Fellowship NSF Graduate Fellowship

Anuska Shrestha 4th year organic student 5/16-present Rackham International Student Fellowship

Ellen Aguilera 3rd year organic student 1/17-present Rackham Merit Fellowship NSF Graduate Fellowship

Pronay Roy 3rd year inorganic student 1/17-present

Naish Lalloo 2nd year organic student 9/17-present

Conor Brigham 2nd year organic student 4/18-present

Yichao Yan 2nd year organic student 4/18-present

Issac Blythe 1st year rotation student 1/19-present Rackham Merit Fellowship

Emily Norwine 1st year rotation student 1/19-present

Ryan Walser-Kuntz 1st year rotation student 1/19-present


Former Graduate Students and Postdoctoral Fellows Benjamin Markovitz MS (2003-2004) Nease Corporation, Cincinnati, OH Dr. Eric Kalberer post-doc (2004-2006) Lubrizol, Akron, OH Dr. Leilani (Welbes) Zart post-doc (2005-2006) Assoc. Professor at Wartburg College Dr. Allison Dick PhD (2003-2007) Asst. Professor at Wheaton College Dr. Paul Zinn post-doc (2006-2007) Nalco Company, Naperville, IL Dr. Lopa Desai PhD (2004-2008) Bristol Myers Squibb, New Brunswick, NJ Dr. Salena Whitfield PhD (2003-2008) Abbott Laboratories, Chicago, IL Dr. Bala Ramanthan post-doc (2007-2008) EAG Chemir, Maryland Heights, MO Dr. Dipannita Kalyani PhD (2004-2008) Merck, Rahway, NJ Dr. Kami Hull PhD (2003-2009) Asst. Professor at U of Illinois, Urbana Champaign Dr. Janette Villalobos post-doc (2007-2009) Proctor and Gamble, Cincinnati, OH Dr. Nicholas Deprez PhD (2005-2009) Merck, Rahway, NJ Dr. Andrew Satterfield post-doc (2009-2010) Exxon-Mobil, Philadelphia, PA Dr. Andrew Higgs PhD (2006-2010) Research Coordinator, University of Michigan Dr. Thomas Lyons PhD (2006-2010) Merck, Boston, MA Dr. Nicholas Ball PhD (2006-2010) Asst. Professor at Pomona College Dr. Matthew Remy PhD (2006-2011) Dow Chemical, Midland, MI Dr. Marion Emmert post-doc (2009-2011) Merck, Rahway, NJ Dr. Amanda Hickman PhD (2008-2011) UOP, A Honeywell Company, Chicago, IL Dr. Joy Racowski PhD (2007-2011) Covert Manufacturing, Mansfield, OH Dr. Kara Stowers PhD (2007-2012) Asst. Professor at BYU Dr. Brannon Gary PhD (2008-2011) Asst. Prof at Stephen F. Austin State University Dr. Kevin Fortner post-doc (2009-2012) Eli Lilly, Indianapolis, IN Dr. Rebecca Loy post-doc (2009-2012) Lecturer at Boston University, Boston, MA Dr. Asako Kubota PhD (2008-2012) Cooley LLP, Boston, MA Dr. Sharon Neufeldt PhD (2007-2012) Asst. Professor at Montana State University Dr. Thomas Droge post-doc (2012-2013) Bayer Crop Science, Germany Dr. Yingda Ye PhD (2009-2013) Incyte Pharmaceuticals, Wilmington, DE Dr. Laura Allen post-doc (2012-2013) Scotts Miracle Grow, Columbus, OH Tiffiny Micyus MS (2012-2013) Paragon Laboratories, Livonia, MI Dr. Chelsea Huff PhD (2010-2014) GlaxoSmithKline, Philadelphia, PA Dr. Anna Wagner PhD (2010-2014) Gilead, Foster City, CA Dr. Ansis Maleckis PhD (2010-2014) Latvian Institute of Organic Synthesis Dr. Doug Genna post-doc (2012-2014) Assoc. Professor at Youngstown State University Dr. James Suttil post-doc (2013-2014) Phillips-66, Bartlesville, OK Dr. Kate McMurtrey PhD (2010-2014) unknown Dr. Sarah Ryan post-doc (2013-2014) Eli Lilly, Indianapolis, IN Dr. Rachel Brooner post-doc (2013-2015) Dow Chemical, Midland, MI Dr. Monica Lotz PhD (2011-2015) Exxon-Mobil, Houston, TX Dr. Amanda Cook PhD (2011-2015) University of Oregon, Asst. Prof. Dr. Monica Perez post-doc (2012-2015) Asst. Professor at ICIQ, Tarragona, Spain Dr. Joseph Topczewski post-doc (2013-2015) Asst. Professor at University of Minnesota Dr. Naoko Ichiishi PhD (2012-2016) Takeda Pharmaceuticals, Cambridge, MA Dr. Shoshanna Barnett post-doc (2015-2016) Viz General Dynamics, Pittsburgh, PA Dr. Curren Mbofana post-doc (2015-2016) Eli Lilly, Indianapolis, IN Dr. Anna Dunn post-doc (2015-2016) GlaxoSmithKline, Philadelphia, PA Dr. Megan Cismesia post-doc (2015-2017) Corteva Agrisciences, Indianapolis, IN Dr. Matt McCammant post-doc (2015-2017) Incyte Pharmaceuticals, Wilmington, DE Dr. Pablo Cabrera PhD (2013-2017) Corteva Agrisciences, Indianapolis, IN Dr. Christo Sevov post-doc (2014-2017) Asst. Professor at Ohio State University Dr. Nicole Camasso PhD (2013-2017) Assistant Managing Editor at JACS Dr. Sydonie Schimler PhD (2013-2017) Dow Chemical, Midland, MI Dr. Eugene Chong post-doc (2015-2017) Boehringer Ingelheim, Ridgefield, CT Dr. Koen Hendriks post-doc (2016-2018) DIFFER, Netherlands Dr. Nomaan Rezayee PhD (2013-2017) Post-doc with KA Jorgenson at Aarhus University Dr. Ian Pendleton PhD (2013-2017) Post-doc with Prof. Schrier at Haveford College Dr. Melissa Lee PhD (2014-2018) Corteva Agrisciences, Indianapolis, IN

Melanie S. Sanford p. 22 Dr. Danielle Samblanet PhD (2014-2018) Wolf, Greenfield & Sacks, Boston, MA Dr. James Bour PhD (2014-2018) Post-doc with M Dinca at MIT Dr. Bryant James PhD (2014-2018) Intel, Portand, OR

Former Undergraduate Students

Kelsey Yee unknown *Waseem Anani Currently: Medical student, Penn State University Jia Ye Hu Currently: Ph. D. student (chemistry), Emory University Vanessa Guzman unknown Henderson Williams unknown *Andrew Krause Currently: Law School at Columbia University Emily Mirkin unknown Sylvia Kunakom Currently: Ph. D. student (chemistry), University of Erlengen-Nuremberg, Germany *Megan Cismesia Currently: Dow Chemical, Midland, MI Shannon Anderson Currently: Ph. D. student (chemical engineering) *Joy Xie Currently: Ph. D. student (biomedical engineering), MIT Catherine Hwang Currently: MPH program at Johns Hopkins University Bryant James Currently: Ph. D. student (chemistry), Michigan *Cydney Seigerman Currently: Ph. D. student (anthropology), Georgia Raymond Strobel Current: medical student, Michigan *Shin Hee Lee Currently: Ph. D. student (chemistry), Yale *Noam Saper Currently: Ph. D. student (chemistry), Berkeley Josephine Eshon Currently: Ph. D. student (chemistry), Wisconsin Tiara Brown Currently: Ph. D. student (chemistry), Illinois *Stavros Kariofilis Current: Ph.D. student (chemistry), Princeton Marisa Lavagnino Current: Ph.D. student (chemistry), Princeton *Sharmilla Sharmaroo Current: Phillips 66 *James Lawnziak Current: Ph.D. student (chemistry), Caltech Maria Morales Colon Current: Ph. D. student (chemistry), Michigan Geraldo Camacho Current, Puerto Rico, undergrad Shay Nguyen Current: UCSB, undergrad Zohaib Siddiqi Current: Ph. D. student (chemistry), Illinois [*] denotes one or more publications as undergrad in MSS group


DEPARTMENTAL ACTIVITIES AND SERVICE (CURRENT):

Chemistry Department Executive Committee 2017-present Chair ad hoc committees for Associate Professors Bart Bartlett and Nate Szymczak Chair ad hoc committee for Assistant Professor Alison Narayan Member ad hoc committee for Associate Professor Pavel Nagorny, Paul Zimmerman Member ad hoc committee for Assistant Professor Aaron Frank UNIVERSITY SERVICE AND ACTIVITIES (CURRENT):

LSA Executive Committee 2018-present Research Administration Advisory Council 2017-present

DEPARTMENTAL AND UNIVERSITY SERVICE (PREVIOUS, SELECTED):

Provost’s Student Learning Advisory Committee, 3rd Century Initiative (Chair) 2012-2016 Key accomplishments include launching and overseeing $25M in grants to promote engaged learning at UM across all schools/colleges Chemistry Department Graduate Committee 2009-2012

Chair (key accomplishments include instituting 4th year meeting for 2010-2012 graduate students to ensure timely progress to degree & initiating chemistry department MS and ADP programs)

Chemistry Department Search Committee 2004-10, 2013 Chair (successfully hired four junior faculty) 2013 Chemistry Department Admissions Committee 2005-2008 Convener of Launch Committee

Asst. Prof. Emily Rauscher, Astronomy 2015-2016 Asst. Professor Alex Rosati, Psychology 2017-2018

Provost’s Council on Student Honors 2012-2013 UMEI Director’s Search Committee 2018 Selection committees of Thurnau Professor, Rackham Merit Fellows, Rackham

Faculty Awards


PROFESSIONAL SERVICE AND ACTIVITIES (CURRENT):

Associate Editor for the Journal of the American Chemical Society (2014-present) A. P. Sloan Research Fellows Selection Committee (2016-present) Welch Foundation Scientific Advisory Board (2019-present) National Science Foundation Advisory Committee for Mathematical and Physical Sciences (2014-present) ICIQ International Advisory Board (2014-present) External Advisory Board for the Institute for Integrated Catalysis at the Pacific Northwest National Laboratory (2013-present) Member of Editorial Advisory Board for Asian Journal of Organic Chemistry (2009-present) Member of Editorial Advisory Board for Synthesis and Synlett (2009-present) Member of Editorial Advisory Board of Advanced Synthesis and Catalysis (2011-present) Member of Editorial Advisory Board for Acc. Chem. Res. (2014-present) PROFESSIONAL SERVICE AND ACTIVITIES (PREVIOUS, SELECTED): Permanent Member NIH SBCB Study Section (2011-2016) AAAS Member-at-Large, Chemistry Section (2012-2016) Associate Editor for Chemical Science (2012-2014) Member Executive Committee for Center for Enabling New Technologies through Catalysis (2012-present) External Advisory Board for the Center for Sustainable Polymers, University of Minnesota (2013-present) External Advisory Board for Princeton University Department of Chemistry (2016)


COURSES:

Chemistry 540: Organic Principles (graduate physical organic course) F 03-06,10-12 Chemistry 312: Synthesis (advanced undergraduate lab) W 04 Chemistry 215HH: Structure and Reactivity (honors 2nd semester undergraduate organic) W 05,09,14,15 Chemistry 711: Organometallic Chemistry (graduate course) W 05 Chemistry 515/Macro 518: Organometallic Chemistry (graduate course) W 07,11,12,16,17,19 Chemistry 210: Structure and Reactivity (1st semester undergraduate organic) F 07-09 Chemistry 215: Structure and Reactivity (2nd semester undergraduate organic) W 13, 18 Chemistry 211H: Introductory Organic Chemistry Laboratory (1st semester lab) F 13, 14 Chemistry 419: Physical Organic Chemistry (upper level undergraduate) F 15, 17

Summary of Teaching

Semester Course Course Name Role Enrollment Q1* Q2* Average

Grade Fall 2003 Chemistry

540 (Graduate)

Organic Principles

1º Instructor 24 4.54 4.73 B+

Winter 2004 Chemistry 312

(Undergrad)

Synthesis 1º Instructor 9 4.38 4.28 B+

Fall 2004 Chemistry 540

(Graduate)

Organic Principles

1º Instructor 29 4.25 4.65 A–

Winter 2005 Chemistry 215HH

(Undergrad)

Structure and Reactivity II

1º Instructor 72 4.53 4.77 B+/A–


(Graduate)

Organic Principles



(Graduate)

Organic Principles


Winter 2007 Chemistry 515/Macro

518 (Graduate)

Organometallic Chemistry



(Undergrad)

Structure and Reactivity I

1º Instructor 359 3.95 4.26 B–


(Undergrad)


1º instructor 383 3.96 4.28 B–


(Undergrad)


1º instructor 83 4.53 4.84 B+/A–


(Undergrad)


1º Instructor 274 4.19 4.76 B–


(Graduate)

Organic Principles



(Graduate)





(Graduate)

Organic Principles



(Graduate)


1º Instructor 15 4.29 4.81 A–/B+


(Graduate)

Organic Principles



(Undergrad)


1º instructor 249 4.51 4.89 B–

Fall 2013 Chemistry 211H

(Undergrad)

Investigations in Chemistry

1º instructor 90 4.03 4.63 B+


(Undergrad)


1º instructor 99 4.44 4.87 A–/B+

Fall 2014 Chemistry 211H

(Undergrad)

Investigations in Chemistry

1º instructor 85 3.89 4.60 A–/B+


(Undergrad)


1º instructor 68 4.52 4.82 B+


(Undergrad)

Physical Organic

Chemistry



(Graduate)


1º Instructor 42 4.77 4.99 B+/A–


(Undergrad)

Physical Organic

Chemistry

1º instructor 48 4.50 4.73 A–


(Undergrad)


1º instructor 345 4.12 4.63 B


(Graduate)


1º Instructor 35 na na na

melanie s. sanford

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