meiosis and mitosis difference

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    Meiosis A Source of Distinction

    Why do you share some but not all characters of each parent?

    What are the rules of this sharing game?

    At one level, the

    answers lie inmeiosis.

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    Meiosis does two things -

    1) Meiosis takes a cell with two copies of everychromosome (diploid) and makes cells with a

    single copy of every chromosome (haploid).

    This is a good idea if youre going to combine

    two cells to make a new organism. This trick

    is accomplished by halving chromosome

    number.

    In meiosis, one diploid cells produces four

    haploid cells.

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    Why do we need meiosis?

    Meiosis is necessary to halve the number

    of chromosomes going into the sex cells

    Why halve the chromosomes in gametes?

    At fertilization the male and female sex

    cells will provide of the chromosomeseach so the offspring has genes from

    both parents

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    2) Meiosis scrambles the specific forms of

    each gene that each sex cell (egg or sperm)receives.

    This makes for a lot ofgenetic diversity. Thistrick is accomplished through independent

    assortment and crossing-over.

    Genetic diversity is important for the evolution

    of populations and species.

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    Meiosis

    Parent cell

    chromosome pair

    Chromosomescopied

    1st division - pairs split

    2nd division produces

    4 gamete cells with

    the original no. of

    chromosomes

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    Meiosis mouse testes

    Parent cell

    4 gametes

    1st division

    2nd division

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    The Stages of Meiosis:

    aka: Reduction Division

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    Meiosis I : Separates

    Homologous Chromosomes

    Interphase

    Each of the chromosomes replicate

    The result is two genetically identicalsister chromatids which remain

    attached at their centromeres

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    Prophase I

    This is a crucial phase for mitosis.

    During this phase each pair ofchromatids dont move to the equatoralone, they match up with their

    homologous pair and fasten together(synapsis) in a group of four called atetrad.

    Extremely IMPORTANT!!! It is during thisphase that crossing over can occur.

    Crossing Over is the exchange ofsegments during synapsis.

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    Metaphase I

    The chromosomes line up at the

    equator attached by their

    centromeres to spindle fibers fromcentrioles.

    Still in homologous pairs

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    Anaphase I

    The spindle guides the movement of the

    chromosomes toward the poles

    Sister chromatids remain attached

    Move as a unit towards the same pole

    The homologous chromosome moves

    toward the opposite pole

    Contrasts mitosis chromosomes appear as

    individuals instead of pairs (meiosis)

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    Telophase I

    This is the end of the first meiotic cell

    division.

    The cytoplasm divides, forming two

    new daughter cells.

    Each of the newly formed cells has

    half the number of the parent cells

    chromosomes, but each chromosomeis already replicated ready for the

    second meiotic cell division

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    Cytokinesis

    Occurs simultaneously withtelophase I Forms 2 daughter cells

    Plant cells cell plate Animal cells cleavage furrows

    NO FURTHER REPLICATION OF

    GENETIC MATERIAL PRIOR TOTHE SECOND DIVISION OFMEIOSIS

    Fi 13 Th f i i ll di i i M i i I

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    Figure 13.7 The stages of meiotic cell division: Meiosis I

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    Meiosis II :Separates sister chromatids

    Proceeds similar to mitosis

    THERE IS NO INTERPHASE II !

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    Prophase II

    Each of the daughter cells forms a

    spindle, and the double stranded

    chromosomes move toward theequator

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    Metaphase II

    The chromosomes are positioned

    on the metaphase plate in a mitosis-

    like fashion

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    Anaphase II

    The centromeres of sister

    chromatids finally separate

    The sister chromatids of each pairmove toward opposite poles

    Now individual chromosomes

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    Telophase II and Cytokinesis

    Nuclei form at opposite poles of the

    cell and cytokinesis occurs

    After completion of cytokinesis thereare four daughter cells

    All are haploid (n)

    Figure 13 7 The stages of meiotic cell division: Meiosis II

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    Figure 13.7 The stages of meiotic cell division: Meiosis II

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    One Way Meiosis Makes Lots of

    Different Sex Cells (Gametes)

    Independent Assortment

    Independent assortment produces 2n

    distinct gametes, where n = the number

    of unique chromosomes.

    Thats a lot of diversity by this

    mechanism alone.

    In humans, n = 23 and 223 = 6,000,0000.

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    Another Way Meiosis Makes Lots of Different

    Sex Cells Crossing-Over

    Crossing-over multiplies the already huge number of different gamete

    types produced by independent assortment.

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    The Key Difference Between Mitosis and Meiosis is

    the Way Chromosomes Uniquely Pair and Align in

    Meiosis

    Mitosis The first (and

    distinguishing)

    division of meiosis

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