Medical Professionals Webcast & Conference Call

Jamie McManus, MD&

Health Sciences Team

AGENDA

•Landmark Study Update

•American Heart Health Month & Cinch

•Special Guest, Peter Sacks, MD

•Q&A

Usage patterns, health, and nutritional status of long-term multiple dietary supplement

users: a cross-sectional study

The Shaklee Landmark 50th Anniversary Study

 

                       

Research                     Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study Gladys Block, Christopher D Jensen, Edward P Norkus, Tapashi B Dalvi, Les G Wong, Jamie F McManus, Mark L HudesNutrition Journal 2007, 6:30 (24 October 2007)[Abstract] [Provisional PDF] [PubMed] [Related articles]

Published October 24, 2007

OVERALL DISEASE PREVALENCE

Risk of Diabetes and Elevated Blood Pressure

Multiple Supplement users were:

•73% less likely to have diabetes

•39% less likely to have elevated blood pressure

Long-term multiple supplement users had:

IN SUMMARY

Greater Supplement

Intake

Higher Nutrition

Levels

Oprimized Bio-Markers

Better Health

Status

www.landmarkstudy.com

A recent article published in BioMed Central's open access Nutrition Journal concerning the usage patterns of dietary supplements and the health and nutritional status of their users has been downloaded from the journal's website over 16,000 times since publication on October 24 th.

…The case actually provides a very nice example of a scenario where open access to the full text is extremely useful, for professional and lay person alike….

The funding of the study (which came from Shaklee), and the competing interests of the researchers, are clearly set out in the article. Not only that, but because Nutrition Journal operates an open peer review policy, the external peer reviewers' identities. their comments and criticisms, and the authors responses and revisions, are all open to scrutiny.

BioMed Central Blog  

SATURDAY NOV 17, 2007

Highly accessed Nutrition Journal article on supplement usage demonstrates key benefit of open access

•#1 most accessed article in the last 30 days! •#3 most accessed article in 2007 despite late

publication on October 24, 2007!

Open Access Advantages

Usage Patterns, Health, and Nutritional Status of Long-Term Multiple Dietary Supplement Users: a Cross-Sectional Study

October - 29 - 2007 A cross-sectional study was conducted to assess the usage patterns, health, and nutritional status of individuals consuming multiple dietary

supplements compared to those who took no supplements or who took only a single multivitamin/mineral supplement.  The methods used were online questionnaires and assessment of physical factors, such as blood

pressure and body weight, and the survey involved a single brand of supplement…  According to the results, long-term, multiple dietary supplement users were not as likely to have high blood pressure,

diabetes, and suboptimal blood nutrient concentrations as non-users and multivitamin/mineral users.

http://professional.diabetes.org/News_Display.aspx?CID=57905&TYP=9

January 22-25, 2008Gainey Ranch, Scottsdale, AZ

“An analysis of Shaklee's multiple dietary supplement user study”

People are taking notice

American Heart Month & Obesity

February is American Heart Month

Cardiovascular disease, although largely preventable, is still the

single greatest cause of death in the US each year.

(*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person)

15-19% ≥20%

Source: Behavioral Risk Factor Surveillance System, CDC.

More than 66% of Americans are overweight to obese.

Obesity Epidemic

StrokeDyslipidemiaHypertensionOsteoarthritis

Type 2 diabetes Gallbladder disease

Coronary heart disease Sleep apnea and respiratory problems

Some cancers (endometrial, breast, and colon)

Health Consequences of Obesity

The Financial Burden

• Illnesses associated with obesity cost the US ~$90.7 billion a year in healthcare costs*

• The cost of treating diabetes complications in the U.S. was estimated at $22.9 billion in 2006.**

• An obese person pays 40% more in doctor visits, procedures, and medications*

*University of Pennsylvania, Professor Adam Gilden Tsai

** American Association of Clinical Endocrinologists (AACE )

If you…PREVENT MUSCLE LOSS

You will…PROTECT METABOLISM

(Muscle = Metabolism)

And the result is…ENHANCED FAT LOSS leading to weight loss and inch loss

Our Scientific Insight

The Power of Leucine

• Essential Amino Acid

• Stimulates Protein Synthesis

• Suppresses Protein Breakdown

As part of a macronutrient balanced program, leucine helps to:

• Promotes satiety• Supports metabolic rate via ability to

preserve muscle

AND

A plan for the rest us

Keep muscle you have.Burn fat you don’t need.

Lose inches you don’t want.

Formulated to help break the diet cycle, so you can:

• Meal Replacement • With proprietary Cinch Pro™

protein blend enhanced with Leucine

• 24 grams of protein when made as directed

• Low glycemic• No artificial colors,

sweeteners, or flavors

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multimineral formula • Cinch Boost™, an exclusive

blend with EGCG to boost calorie burning*

• Helps retain normal blood sugar levels, which may help control food cravings with chromium, vanadium, and banaba leaf extract*

3-in-1 Boost™

*These statements have not been evaluated the Food and Drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

•Alternative to meal replacement shake•HUGE 70 gram bar •Powered by Leucine™•Only 260-270 Calories•20 grams of Protein•No artificial colors, flavors or sweeteners

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Berry Almond Crunch

Peanut ButterChocolate Chip

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• Exclusive T-Lift™ Blend with exotic green, red, and white teas

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• A proprietary formula Powered by Leucine™

• 10 grams of protein• 120–130 calories per

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Getting Started.

Basic Daily Plan:• 2 Cinch Shakes/ Meal Bar• Cinch Snack Bar & Tea• 3-in-1 Boost Supplement with each meal• Correctly proportioned meal (Structured or Flexible Approach Meal Plans) • Calorie levels include: 1200, 1500, 1800, 2100

Interactive website: -Recipes, meal plans, tips & tools

-Online learning Center

-Community Forums

-Success Stories

-FAQ’s

Special Guest Peter Sacks, MD

Physician, Internal MedicineInternational and Special

Services in the Division of Internal Medicine at Scripps

Clinic and Research Foundation, La Jolla,

California

Areas of Expertise: Internal Medicine, Nutrition and Weight

Control

20 Year Shaklee Scientific Advisory Board Member

Peter Sacks M.D.

50+ Years of Science & SuccessThank you for your participation.

If we are unable to answer your question, please email medicalaffairs@shaklee.com