The University of Texas MD Anderson Cancer Center

R. Lee Clark ClinicFloor 11, Hickey Auditorium1515 Holcombe Boulevard

Houston, Texas

Medical Oncologyand Hematology 2012:

Clinical and Scientific Approaches that Enhance Patient Outcomes

October 18–20, 2012

Program ChairHagop M. Kantarjian, MD

Organizing Committee

Medical Oncology and Hematology 2012:Clinical and Scientific Approaches that Enhance Patient Outcomes

October 18–20, 2012 The University of Texas MD Anderson Cancer Center

R. Lee Clark Clinic, Floor 11 – Hickey Auditorium, 1515 Holcombe Boulevard, Houston, Texas

GoalThe goal of this program will be to address the ongoing need for education of practicing physicians with new cancer therapy and updating treatment guidelines and focus on new advances within the last year and other groundbreaking scientific discoveries. At the conclusion of the conference, physicians and other healthcare providers will have a new awareness and knowledge in optimal use of new therapies for cancer.

Educational ObjectivesAfter attending the conference, participants should be able to• Incorporate new knowledge for each cancer diagnosis to articulate optimal

treatments guided by prognostic factors and treatment options (Knowledge, Competence, Performance, and Patient Outcomes).

•Utilizeavailableclinicaltrialsforpromisingnewtreatmentsandappropriatelyselectcandidates for referral (Knowledge, Competence, Performance, and Patient Outcomes).

•Applyprinciplesofpersonalizedcancertreatmentforeachdiagnosis(Knowledge, Competence, Performance, and Patient Outcomes).

•Implementnewknowledgeofcancergeneticstoimprovetreatmentofcancerpatients (Knowledge, Competence, Performance, and Patient Outcomes).

Target AudienceThis conference will be beneficial to primary care physicians, medical oncologists and hematologists, trainees, fellows, and other healthcare professionals.

Program Co-ChairsRaymond N. DuBois, MD, PhDRichard E. Champlin, MDLyle D. Green, MBA

YvonneS.BazunuDoreen BrandenbergerElnar KoseogluTina Nelson, CMP

Educational Method•Lectures/Didactic•QuestionandAnswerSession•ConferencePost-Evaluation

EvaluationA course evaluation form will provide participants with the opportunity to comment on the value of the program content to their practice decisions, performance improvement activities, or possible impact on patient health status. Participants will also have the opportunity to comment on any perceived commercial bias in the presentations as well as to identify future educational topics.

Accreditation/Credit DesignationThe University of Texas MD Anderson Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The University of Texas MD Anderson Cancer Center designates this live activity for a maximum of 14.50 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CME Certificates and Attendance Verification CertificatesCertificates awarding AMA PRA Category 1 CreditTM or certificates documenting attendance will be distributed to participants when an individual departs the conference. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form.

Upon request, a record of attendance (certificate) will be provided on-sitetootherhealthcareprofessionalsforrequestingcreditsinaccordance with state nursing boards, specialty societies, or other professional associations.

Follow @Physrelations on TwitterGet real-time conference updates and join the discussion with The #MOHC2012 hashtag. Join us for a joint reception/tweetup at 5:30 p.m. on Friday, October 19, 2012.

Program Thursday, October 18, 20122:00 pm Registration

3:00 Welcome and Opening Remarks Raymond N. DuBois, MD, PhD

PLENARY SESSIONS

3:15 Overview of Clinical Trials Aman U. Buzdar, MD

4:00 Translating the Cancer Genome Lynda Chin, MD

4:45 Closing Remarks/Preview of Day Two Peter C. Hu, PhD

What’s New in Solid Tumors? THORACIC/HEAD & NECK SESSION

8:40 The Importance of Molecular Diagnostics and Therapy in Lung Cancer

George R. Blumenschein, Jr., MD

9:00 Latest Treatments of Head and Neck Cancer Merrill S. Kies, MD

9:20 Ask the Experts

9:35 Break

GENITOURINARY SESSION

9:45 Targeted Therapies in Renal Cell Cancer Nizar M. Tannir, MD

10:05 Prostate Cancer Overview Christopher J. Logothetis, MD

10:25 Testicular Cancer/Germ Cell Tumors Lance C. Pagliaro, MD

10:45 Ask the Experts

BRAIN SESSION

11:00 State-of-the-Art Approach to Brain Tumor Therapy W.K. Alfred Yung, MD

11:20 Ask the Expert

Friday, October 19, 20127:00 am Registration and Continental Breakfast

8:00 Welcome and Opening Remarks Ronald A. DePinho, MD

8:10 KEYNOTE SPEAKER Healthcare Reform - Impact on Cancer Care Thomas W. Burke, MD

PERSONALIZED THERAPY SESSION

11:35 Delivering Personalized Therapy in Solid Tumors Apostolia M. Tsimberidou, MD, PhD

11:55 Ask the Expert

GYNECOLOGICAL SESSION

12:00 pm Lunch (provided) Treatment of Gynecological Cancers Karen H. Lu, MD

12:35 Ask the Expert

GASTROINTESTINAL SESSION

1:00 Esophageal and Gastric Cancer Jaffer A. Ajani, MD

1:30 New Developments in Colorectal Cancer Treatment Arvind Dasari, MBBS

1:50 Pancreas and NET James C. Yao, MD

2:10 Ask the Experts

MELANOMA SESSION

2:25 The Immunotherapy of Melanoma Patrick Hwu, MD

2:40 Targeted Therapy of Melanoma Michael A. Davies, MD, PhD

2:55 Ask the Experts

SARCOMA SESSION

3:10 Overview of Sarcoma Therapy Vinod Ravi, MD

3:30 Ask the Expert

3:45 Break

BREAST SESSION

4:00 Treatment of Early Stage Breast Cancer Vicente Valero, MD

4:20 Treatment of Late Stage Breast Cancer Ricardo Hugo Alvarez, MD

4:40 Novel Strategies for Inflammatory Breast Cancer Naoto T. Ueno, MD, PhD

5:00 Ask the Experts

5:15 Adjourn

5:30 Bienvenido a la Recepción - Please Join Us (Come visit with Colleagues)

Ronald A. DePinho, MDProfessor, President

Thomas W. Burke, MDProfessor, Executive Vice PresidentandPhysician-In-Chief

Raymond N. DuBois, MD, PhDProfessorProvost and Executive Vice President

Jaffer A. Ajani, MDProfessorGastrointestinal Medical Oncology

Ricardo Hugo Alvarez, MDAssistant ProfessorBreast Medical Oncology

George R. Blumenschein, Jr., MDAssociate ProfessorThoracic/Head&Neck Medical Oncology

Aman U. Buzdar, MDProfessor, Breast Medical Oncology

Richard E. Champlin, MDProfessor and ChairStem Cell Transplantation and Cellular Therapy

Lynda Chin, MDProfessor and Chair Genomic Medicine

Jorge E. Cortes, MDProfessor, Leukemia

Arvind Dasari, MBBSAssistant ProfessorGastrointestinal Medical Oncology

Michael A. Davies, MD, PhDAssistant ProfessorMelanoma Medical Oncology

Stefan H. Faderl, MDProfessor, Leukemia

Luis E. Fayad, MDAssociate ProfessorLymphoma/Myeloma

Guillermo Garcia-Manero, MDProfessor, Leukemia

Fredrick B. Hagemeister, MDProfessorLymphoma/Myeloma

Peter C. Hu, PhDAssociate ProfessorSchool of Health Professions

Patrick Hwu, MDProfessor and ChairMelanoma Medical Oncology

Saturday, October 20, 20127:00 am Registration and Continental Breakfast

8:00 Welcome and Opening Remarks Elizabeth Shpall, MD

What’s New in Hematology? HEMATOLOGY SESSION8:10 State-of-the-Art Treatment of Acute Lymphoblastic

Leukemia and Acute Myelogenous Leukemia Stefan H. Faderl, MD

8:30 Treatment of Chronic Myelogenous Leukemia Jorge E. Cortes, MD

8:50 Treatment of Chronic Lymphocytic Leukemia William G. Wierda, MD, PhD

9:10 Treatment of Myelodysplastic Syndrome Guillermo Garcia-Manero, MD

9:30 Ask the Experts

9:45 Break

10:00 Aggressive Lymphomas Luis E. Fayad, MD

10:20 Indolent Lymphomas Fredrick B. Hagemeister, MD

10:40 Hodgkin’s Disease Anas Younes, MD

11:00 Myeloma Jatin Shah, MD

11:20 Ask the Experts

11:35 Novel Strategies in Stem Cell Transplantation Elizabeth Shpall, MD

12:00 pm Closing Remarks and Adjourn

MD ANDERSON FACULTYHagop M. Kantarjian, MDProfessor and ChairLeukemia

Merrill S. Kies, MDProfessorThoracic/HeadandNeck Medical Oncology

Christopher J. Logothetis, MDProfessor and ChairGenitourinary Medical Oncology

Karen H. Lu, MDProfessorGynecologic Oncology

Lance C. Pagliaro, MDAssociate ProfessorGenitourinary Medical Oncology

Vinod Ravi, MDAssistant ProfessorSarcoma Medical Oncology

Jatin Shah, MDAssistant ProfessorLymphoma/Myeloma

Elizabeth Shpall, MDProfessorStem Cell Transplantation

Nizar M. Tannir, MDAssociate ProfessorGenitourinary Medical Oncology

Apostolia M. Tsimberidou, MD, PhDAssociate ProfessorInvestigational Cancer Therapeutics

Naoto T. Ueno, MD, PhDProfessorBreast Medical Oncology

Vicente Valero, MDProfessorBreast Medical Oncology

William G. Wierda, MD, PhDAssociate ProfessorLeukemia

James C. Yao, MDAssociate ProfessorGastrointestinal Medical Oncology

Anas Younes, MDProfessorLymphoma/Myeloma

W.K. Alfred Yung, MDProfessor and ChairNeuro-Oncology

Special AssistanceContacttheDepartmentofCME/ConferenceManagementat713-792-2223ortollfreeat866-849-5866ifyouhaveanyspecialdietaryorADAaccommodationneeds.

Accommodations•AblockofroomshasbeenreservedforconferenceattendeesattheHouston Marriott

at the Texas Medical Center, locatedat6580FanninStreet,Houston,Texas77030•Earlyhotelreservationissuggested.•Thehotelphonenumberis1-800-228-9290.•WhenyoumakereservationsbesuretomentiontheMedical Oncology and

Hematology 2012: “Clinical and Scientific Approaches that Enhance Patient Outcomes” Conference to be assured of receiving the special meeting rate of $122.00singleordoubleoccupancy.Pleaseadd17%(Texas)stateandlocaltaxes.

•ReservationsanddepositsreceivedafterOctober8,2012willbeconfirmedifspace is available and at current hotel published guest room rates.

Air TravelMD Anderson has a program with United Airlines for discounted air travel. For discounts, callyourtravelprofessionalorUnited’sMeetingWorkstollfreeat800-468-7022.Outside of the United States, please call your local United Airlines Reservation Office. Mention Z Code: ZM6M and Agreement Code: 488954.

Ground Transportation (prices are subject to change and variable depending on location of conference) •Houstonisservedbytwoairports,GeorgeBushIntercontinental(IAH)andWilliamP.

Hobby (HOU). •Taxicabsareavailableatanestimatedcostof$50-$60toorfromWilliamP.Hobby

Airport or George Bush Intercontinental Airport. •SuperShuttleoperatesashuttlebusbetweenGeorgeBushIntercontinentalAirport andtheHoustonMarriottattheTexasMedicalCenterfor$27one-wayand$54round- trip.Formoreinformation,call713-523-8888ortollfreeat800-258-3826,oronlineatwww.supershuttle.com.

•SuperShuttleoperatesashuttlebusbetweenWilliamP.HobbyAirportandthe HoustonMarriottattheTexasMedicalCenterfor$24one-wayand$48round-trip. Formoreinformation,call713-523-8888ortoll-freeat800-258-3826,oronlineat www.supershuttle.com.

Pleaseletusknowwhatspecifictopics,issuesorquestionsyouwishtoseeaddressedoremphasizedinthisactivity.Faxore-mailCME/ConferenceManagement.AllresponseswillbeforwardedtotheProgramChair for consideration.

The University of Texas MD Anderson Cancer Center has implemented a process whereby everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships with any commercial interest that could potentially affect the information presented. MD Anderson also requires that all faculty disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Specific disclosure will be made to the participants prior to the educational activity.

Agendas are subject to change because we are always striving to improve the quality of your educational experience. MD Anderson may substitute faculty with comparable expertise on rare occasions necessitated by illness, schedule conflicts, and so forth.

Photographing, audio taping and videotaping are prohibited.

Registration InformationOn-siteregistrationwillopenat2:00p.m.onThursday,October18,2012.Theopeningsessionoftheconferencewillbeginat3:00p.m.onThursday,October18,2012andtheconferencewilladjournonSaturday,October20,2012.

Advance registration is encouraged as space and materials are limited. Please see registration form for applicable fees.

The deadline for advance registration is October 8, 2012.

There are three ways to register:•Mailto:CME/ConferenceManagement–Unit1381,TheUniversityofTexas MDAndersonCancerCenter,P.O.Box301439,Houston,TX77230-1439

•Faxto:713-794-1724•On-lineatwww.mdanderson.org/conferences

We accept the following forms of payment:•Check(payablethroughU.S.banksonly)•MoneyOrder•CreditCards(MasterCard,VISA,andAmericanExpress)•Cash(on-siteregistrationonly)

A receipt and confirmation letter will be sent to you within ten working days of receipt of your fee. The full conference registration fee includes the tuition, syllabus, continental breakfasts, breaks, lunch, and welcome reception.

Refund/Cancellation Policy:The registration fee, minus a $50 administrative handling fee, is refundable ifawrittenrequestisreceivedonorbeforeOctober8,2012.Norefundswillbegrantedafterthat date. The request for a registration refund must include the tax identification number of the company or institution if registration was paid by a company or institution check.

TheDepartmentofCME/ConferenceManagementreservestherighttocancelactivitiespriorto the scheduled date, if low enrollment or other circumstances make it necessary. Each registrantwillbenotifiedbymail,e-mail,orthecontactnumbersasgivenontheregistrationform.Incaseofactivitycancellation,liabilityoftheDepartmentofCME/ConferenceManagementislimitedtotheregistrationfee.CME/ConferenceManagementwillrefundthefullregistrationfee.TheDepartmentofCME/ConferenceManagementreservestherighttolimit the number of participants in a program and is not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available.

Foradditionalinformation,contactCME/ConferenceManagementat713-792-2223ortollfreeat866-849-5866.

THIS

IS N

OT A

SEL

F-M

AILE

R-Ad

dres

s to

: Medica

lOncologya

ndHem

atology2

012

Departm

entofCME/ConferenceManagem

ent–Unit1381

The

Univ

ersi

ty o

f Tex

as M

D An

ders

on C

ance

r Cen

ter

POBox301439,Houston,TX77230-1439

orfaxto713-794-1724

Mak

e ch

eck

or m

oney

ord

er p

ayab

le to

: Th

e Un

iver

sity

of T

exas

MD

Ande

rson

Can

cer C

ente

r

REGI

STRA

TION

FEES

Phys

icia

ns/S

cien

tists

1 P

ostm

arke

d be

fore

10/8

/12 .

........

........

....$1

75.00

1

Pos

tmar

ked

afte

r 10/

8/12

.......

........

........

.$225

.00

MD

Ande

rson

Facu

lty/ A

lum

ni 1

Pos

tmar

ked

befo

re 10

/8/1

2 .....

........

........

$100

.00

1 P

ostm

arke

d af

ter 1

0/8/

12 ...

........

........

.....$1

25.00

Fello

ws/

Stud

ents

/Res

iden

ts 1

Pos

tmar

ked

befo

re 10

/8/1

2 .....

........

........

$ 50

.00

MD

Ande

rson

Sta

ff, Tr

aine

es

& Al

lied

Heal

th P

rofe

ssio

nals

1 P

ostm

arke

d be

fore

10/8

/12 .

........

........

....$

50.00

Heal

thca

re P

rofe

ssio

nals

1 P

ostm

arke

d be

fore

10/8

/12 .

........

........

....$

100.0

0 1

Pos

tmar

ked

afte

r 10/

8/12

.......

........

........

.$ 12

5.00

CO

NFE

REN

CE

REG

ISTR

ATI

ON

- 05

91M

edic

al O

ncol

ogy a

nd H

emat

olog

y 201

2:

Clin

ical

and

Sci

entifi

c Ap

proa

ches

that

Enh

ance

Pat

ient

Out

com

es –

Oct

ober

18–2

0, 20

12

Last

Nam

e

Fi

rst

M

I

H

ighe

st D

egre

e

Depa

rtmen

t (in

clud

e bo

x no

.)

Spe

cial

ty

Inst

itutio

n

Phys

icia

n

Stre

et

City

Sta

te/F

orei

gn C

ount

ry/Z

ip o

r Mai

l Cod

e

Dayt

ime

Phon

e (w

ith a

rea

code

)

Ce

ll Ph

one

(with

are

a co

de)

Fax

(with

are

a co

de)

E-m

ail A

ddre

ss

E

mer

genc

y Co

ntac

t

P

hone

(with

are

a co

de)

Char

ge th

e fo

llow

ing:

o

VISA

oM

aste

rCar

d

o

Amer

ican

Exp

ress

Cred

it Ca

rd N

umbe

r or M

D A

nder

son

Inte

rdep

artm

enta

l Tra

nsfe

r (ID

T) N

o.

Ex

pira

tion

Dat

e

Cred

it Ca

rd H

olde

r Nam

e (F

irst/L

ast)

C

redi

t Car

d Ho

lder

Bill

ing

Addr

ess

& Z

IP C

ode

Aut

horiz

ed S

igna

ture

REQ

UIR

ED fo

r cre

dit c

ard

or ID

T

M

D A

nder

son

Empl

oyee

ID N

o. (R

EQU

IRED

)

IDT

Appr

over

Nam

e (F

irst/L

ast)

plea

se p

rint

IDT

Appr

over

E-m

ail

oYe

s

o

No

Dr. Ronald A. DePinhoPresident, The University of Texas MD Anderson Cancer Center

and

Dr. Hagop M. KantarjianConference Chair, Professor and Chair, Leukemia

Cordially invite you to attend a reception

Friday, October 19, 20125:30 – 7:00 p.m.

The University of Texas MD Anderson Cancer CenterHickey Auditorium Foyer Main Building, Floor 11

1515 Holcombe Blvd., Houston, Texas 77030

This reception is being held in conjunction with theMedical Oncology and Hematology 2012:

Clinical and Scientific Approaches that Enhance Patient Outcomes Conference

Hosted by the Office of Physician Relations

Please Join Us

uuu

The

Uni

vers

ity o

f Te

xas

MD

And

erso

n C

ance

r C

ente

rC

ME

/Con

fere

nce

Man

agem

ent

- Uni

t 13

8117

6700

/300

7059

1P

O B

ox 3

0143

9H

oust

on, T

exas

772

30-1

439

Non-ProfitOrg.

U.S.

Pos

tage

P A

I DHo

uston,TX

PermitNo.7052