medical emergency responders integration and training (merit) real-time ecg data in ohca first...

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Poster Presentations / Resuscitation 83 (2012) e24–e123 e67 References [1].Kerber RE, Becker LB, et al. Automatic external defibrillators for public access defibrillation: recommendations for specifying and reporting arrhythmia analy- sis algorithm performance, incorporating new waveforms, and enhancing safety. Circulation 1997;95:1677–82. [2].Wik L, Kramer-Johansen J, et al. Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest. JAMA 2005;293:299–304. [3].Aramendi E, Irusta U, et al. ECG spectral and morphological parameters reviewed and updated to detect adult and paediatric life-threatening arrhythmia. Physio- logical Measurement 2010;31:749–61. [4].Neurauter A, Eftestøl T, et al. Improving countershock success prediction during cardiopulmonary resuscitation using ventricular fibrillation features from higher ECG frequency bands. Resuscitation 2008;79:453–9. http://dx.doi.org/10.1016/j.resuscitation.2012.08.170 AP112 A simple shock advice algorithm for automated external defib- rillators compliant with the American Heart Association’s recommendations Unai Ayala , Elisabete Aramendi, Erik Alonso, Unai Irusta, Digna Gonzalez-Otero University of the Basque Country UPV/EHU, Bilbao, Bizkaia, Spain Purpose: Although many shock/no-shock discrimination parameters are public, shock advice algorithms (SAA) in commer- cial automated external defibrillators (AED) are proprietary. The American Heart Association (AHA) defined the accuracy require- ments and the composition of the rhythm databases to evaluate AED SAA. 1 The aim of this study is to describe a simple SAA based on well-known discrimination parameters, fully compliant with the AHA recommendations. Materials: ECG records were gathered in-hospital and from out-of-hospital cardiac arrest (OHCA) patients. All records were artefact-free, had a minimum duration of 3 s, contained a single rhythm type and within each rhythm type all patients were dif- ferent. Three expert reviewers classified the records in the rhythm types specified by the AHA statement. The database was split in two, for algorithm development and testing. The test database con- tained: 200 ventricular fibrillation (VF), 99 ventricular tachycardia (VT), 256 asystole (AS), 145 normal sinus rhythm (NSR) and 159 other non-shockable rhythms (Others). Methods: The algorithm processes the ECG in 3 s segments. First, it identifies asystole using a power-threshold on the filtered ECG (2.5–30 Hz). Then, non-asystole segments are filtered (0.5–30 Hz) and the shock/no-shock decision is given by a logistic regression classifier that combines three parameters: TCI, 2 VFleak 3 and Edge Frequency (EF). 4 A majority criterion was applied to classify the records with several segments. Results: The classifier, optimized using the development database, was: Y = 0.02·TCI + 14.12·VFleak + 0.50·EF-21.40 (Y <0 shock, Y >0 no-shock). For the test database sensitiv- ities/specificities and their one-sided lower 90% confidence intervals were: 99.0% (97.5%) for VF, 99.0% (96.5%) for VT, 100% (99.2%) for AS, 99.3% (97.6%) for NSR and 95.6% (93.0%) for Others. Conclusion: A simple SAA compliant with the AHA recommen- dations has been fully described. However, its performance should be tested for real OHCA episodes. References [1].Kerber RE, Becker LB, Bourland JD, et al. Automatic external defibrillators for public access defibrillation: recommendations for specifying and reporting arrhythmia analysis algorithm performance, incorporating new waveforms, and enhancing safety. Circulation 1997;95:1677–82. [2].Thakor N, Zhu YS, Pan KY. Ventricular tachycardia and fibrillation detection by a sequential hypothesis testing algorithm. IEEE Trans Biomed Eng 1990;37:837–43. [3].Kuo S, Dillman R. Computer detection of ventricular fibrillation. In: Computers in Cardiology. US: IEEE Computer Society Press; 1978. p. 347–349. [4].Neurauter A, Eftestøl T, Kramer-Johansen J, et al. Improving countershock success prediction during cardiopulmonary resuscitation using ventricular fibrillation features from higher ECG frequency bands. Resuscitation 2008;79:453–9. http://dx.doi.org/10.1016/j.resuscitation.2012.08.171 AP113 Medical emergency responders integration and train- ing (MERIT) real-time ECG data in OHCA first responder resuscitation: Key messages Gerard Bury , Mairéad Egan, Mary Headon University College Dublin, Dublin, Ireland Introduction: The dynamics of resuscitation can be usefully observed by use of real-time ECG data; examples include recent insights on ‘state transitions’ and the impact of adrenaline on PEA. 1,2 This study uses real-time ECG data to explore cardiac arrest management by GPs in a community setting. Methods: Between 2006 and 2012, MERIT supported AEDs/ALS training at 531 general practice sites in urban, rural and mixed areas. All Cardiac Arrests with Resuscitation Attempts (CARAs) involving these GPs are reported by quarterly survey; clinical and ECG data are collated with a mean response rate of 89% (81–97%). This study reports on key findings from ECG data downloaded from AEDs used in CARAs. In 123/286 CARAs (43%), a GP used a MERIT AED; 87 (70.7%) ECG records were retrieved for analysis. Results: Age, gender, location, witnessed arrest and outcomes are comparable with all CARAs. There were 14/87 (16.7%) sur- vivors, 1/41 (2.4%) in a non-shockable rhythm and 13/46 (28.3%) if shockable. 8/14 (57.1%) survivors received 1 shock, 3/14 (21.4%) 2–4 shocks and 2/14 (14.3%) 5–15 shocks. Patients in a shockable rhythm increased from 43 (49.4%) initially to 47 (54%) with CPR. 45/87 (51.7%) received ALS drugs but only 2/45 (4.4%) survived and 12/14 survivors received no drugs. No survivors occurred after a resuscitation duration of 13 min. In 51/87 (58.6%) at least one state transition occurred (median 2 overall). Conclusions: These data confirm the impact of early CPR and defibrillation and the poor outcomes of non-shockable rhythms. Drug therapy contributes in few cases and most survivors are resuscitated with small numbers of shocks and within 13 min. Community based survivors result principally from early CPR and defibrillation. References [1].Nordseth T, et al. Dynamic effects of adrenaline in OHCA with initial PEA. Resus- citation 2012 [epub]. [2].Skogvoll, et al. Dynamics and state transitions during resuscitation in OHCA. Resuscitation 2008;78:30–7. http://dx.doi.org/10.1016/j.resuscitation.2012.08.172

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[2].Skogvoll, et al. Dynamics and state transitions during resuscitation in OHCA.Resuscitation 2008;78:30–7.

http://dx.doi.org/10.1016/j.resuscitation.2012.08.172

Poster Presentations / Res

eferences

].Kerber RE, Becker LB, et al. Automatic external defibrillators for public accessdefibrillation: recommendations for specifying and reporting arrhythmia analy-sis algorithm performance, incorporating new waveforms, and enhancing safety.Circulation 1997;95:1677–82.

].Wik L, Kramer-Johansen J, et al. Quality of cardiopulmonary resuscitation duringout-of-hospital cardiac arrest. JAMA 2005;293:299–304.

].Aramendi E, Irusta U, et al. ECG spectral and morphological parameters reviewedand updated to detect adult and paediatric life-threatening arrhythmia. Physio-logical Measurement 2010;31:749–61.

].Neurauter A, Eftestøl T, et al. Improving countershock success prediction duringcardiopulmonary resuscitation using ventricular fibrillation features from higherECG frequency bands. Resuscitation 2008;79:453–9.

ttp://dx.doi.org/10.1016/j.resuscitation.2012.08.170

P112

simple shock advice algorithm for automated external defib-illators compliant with the American Heart Association’secommendations

nai Ayala ∗, Elisabete Aramendi, Erik Alonso, Unai Irusta, Dignaonzalez-Otero

University of the Basque Country UPV/EHU, Bilbao, Bizkaia, Spain

Purpose: Although many shock/no-shock discriminationarameters are public, shock advice algorithms (SAA) in commer-ial automated external defibrillators (AED) are proprietary. Themerican Heart Association (AHA) defined the accuracy require-ents and the composition of the rhythm databases to evaluateED SAA.1 The aim of this study is to describe a simple SAA basedn well-known discrimination parameters, fully compliant withhe AHA recommendations.

Materials: ECG records were gathered in-hospital and fromut-of-hospital cardiac arrest (OHCA) patients. All records werertefact-free, had a minimum duration of 3 s, contained a singlehythm type and within each rhythm type all patients were dif-erent. Three expert reviewers classified the records in the rhythmypes specified by the AHA statement. The database was split inwo, for algorithm development and testing. The test database con-ained: 200 ventricular fibrillation (VF), 99 ventricular tachycardiaVT), 256 asystole (AS), 145 normal sinus rhythm (NSR) and 159ther non-shockable rhythms (Others).

Methods: The algorithm processes the ECG in 3 s segments. First,t identifies asystole using a power-threshold on the filtered ECG2.5–30 Hz). Then, non-asystole segments are filtered (0.5–30 Hz)nd the shock/no-shock decision is given by a logistic regressionlassifier that combines three parameters: TCI,2 VFleak3 and Edgerequency (EF).4 A majority criterion was applied to classify theecords with several segments.

Results: The classifier, optimized using the developmentatabase, was: Y = 0.02·TCI + 14.12·VFleak + 0.50·EF-21.40Y < 0 shock, Y > 0 no-shock). For the test database sensitiv-ties/specificities and their one-sided lower 90% confidencentervals were: 99.0% (97.5%) for VF, 99.0% (96.5%) for VT, 100%99.2%) for AS, 99.3% (97.6%) for NSR and 95.6% (93.0%) for Others.

Conclusion: A simple SAA compliant with the AHA recommen-ations has been fully described. However, its performance shoulde tested for real OHCA episodes.

eferences

].Kerber RE, Becker LB, Bourland JD, et al. Automatic external defibrillators for public

access defibrillation: recommendations for specifying and reporting arrhythmiaanalysis algorithm performance, incorporating new waveforms, and enhancingsafety. Circulation 1997;95:1677–82.

].Thakor N, Zhu YS, Pan KY. Ventricular tachycardia and fibrillation detection by asequential hypothesis testing algorithm. IEEE Trans Biomed Eng 1990;37:837–43.

tion 83 (2012) e24–e123 e67

].Kuo S, Dillman R. Computer detection of ventricular fibrillation. In: Computers inCardiology. US: IEEE Computer Society Press; 1978. p. 347–349.

].Neurauter A, Eftestøl T, Kramer-Johansen J, et al. Improving countershock successprediction during cardiopulmonary resuscitation using ventricular fibrillationfeatures from higher ECG frequency bands. Resuscitation 2008;79:453–9.

http://dx.doi.org/10.1016/j.resuscitation.2012.08.171

AP113

Medical emergency responders integration and train-ing (MERIT) real-time ECG data in OHCA first responderresuscitation: Key messages

Gerard Bury ∗, Mairéad Egan, Mary Headon

University College Dublin, Dublin, Ireland

Introduction: The dynamics of resuscitation can be usefullyobserved by use of real-time ECG data; examples include recentinsights on ‘state transitions’ and the impact of adrenaline onPEA.1,2

This study uses real-time ECG data to explore cardiac arrestmanagement by GPs in a community setting.

Methods: Between 2006 and 2012, MERIT supported AEDs/ALStraining at 531 general practice sites in urban, rural and mixedareas. All Cardiac Arrests with Resuscitation Attempts (CARAs)involving these GPs are reported by quarterly survey; clinical andECG data are collated with a mean response rate of 89% (81–97%).This study reports on key findings from ECG data downloaded fromAEDs used in CARAs. In 123/286 CARAs (43%), a GP used a MERITAED; 87 (70.7%) ECG records were retrieved for analysis.

Results: Age, gender, location, witnessed arrest and outcomesare comparable with all CARAs. There were 14/87 (16.7%) sur-vivors, 1/41 (2.4%) in a non-shockable rhythm and 13/46 (28.3%)if shockable. 8/14 (57.1%) survivors received 1 shock, 3/14 (21.4%)2–4 shocks and 2/14 (14.3%) 5–15 shocks. Patients in a shockablerhythm increased from 43 (49.4%) initially to 47 (54%) with CPR.45/87 (51.7%) received ALS drugs but only 2/45 (4.4%) survived and12/14 survivors received no drugs. No survivors occurred after aresuscitation duration of 13 min. In 51/87 (58.6%) at least one statetransition occurred (median 2 overall).

Conclusions: These data confirm the impact of early CPR anddefibrillation and the poor outcomes of non-shockable rhythms.Drug therapy contributes in few cases and most survivors areresuscitated with small numbers of shocks and within 13 min.Community based survivors result principally from early CPR anddefibrillation.

References

].Nordseth T, et al. Dynamic effects of adrenaline in OHCA with initial PEA. Resus-citation 2012 [epub].