med lez 20 met aa gluconeogenesi
TRANSCRIPT
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GLUCONEOGENESI
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► DOVE ? FEGATO (90%)
►QUANDO ?? Dopo 4-6 ore digiuno
PRECURSORI
►Glicerolo
►Amminoacidi gluconeogenetici
►Lattato
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AMMINOACIDI
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LATTATO
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GLICEROLO
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GLICOLISI
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1 TAPPA IRREVERSIBILE
PIRUVATO CARBOSSILASI
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1 TAPPA IRREVERSIBILE
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GLICOLISI
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2 TAPPA IRREVERSIBILE
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GLICOLISI
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3 TAPPA IRREVERSIBILE
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3 TAPPA IRREVERSIBILE
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REGOLAZIONE
► GLUCAGONE
PIRUVATO CHINASI
sintesi della PEP CARBOSSICHINASI
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PFK 1GLUCAGONE
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REGOLAZIONE
► SUBSTRATI
►Acetil-CoA
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TAPPA IMPOSSIBILE
ACETYL–CoA
PIRUVATO
GLUCOSIO
NON SI PUO’ CONVERTIRE GLI
ACIDI GRASSI IN GLUCIDI
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2 ATP 4 ATP 2 GTP
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BIOSINTESI
AMMINOACIDI
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SINTESI
SERINA
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SINTESI GLICINA
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GLICINA SERINA
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SINTESI CATECOLAMMINE
Vit B6
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CARNITINA
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CREATINA
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