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Material Safety Data SheetProduct code: 7900001/4771Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Cell FixativeProduct code: 7900001/4771Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Harmful if swallowed.May be harmful in contact with skin.Product contains animal-derived material.May cause sensitization by skin contact.This product may cause eye irritation.
Indication of danger: Xn - Harmful.
Product name: Cell FixativeCompany: Janssen Diagnostics, LLC
Page 1 of 6Product code: 7900001/4771
Most important hazardsRisk Phrase R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSodium Azide 26628-22-8 0.1 247-852-1 T+;R28-32
N;R50-53Serum Albumin 9048-46-8 0.1 232-936-2
4. FIRST AID MEASURES
Eye contact: In the case of contact with eyes, rinse immediately with plenty of water for 15 minutes and seekmedical attention.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth. Do not induce vomitingwithout medical advice. Obtain medical attention.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product code: 7900001/4771Product name: Cell FixativeCompany: Janssen Diagnostics, LLC
Page 2 of 6
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components Australia Hong Kong Japan India Korea Malaysia ChinaSodium Azide (0.1%)26628-22-8
Ceiling 0.1 ppmCeiling 0.3
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
MAC 0.3 mg/m3
Components New Zealand Philippines Singapore Taiwan Thailand ACGIH OEL IndonesiaSodium Azide (0.1%)26628-22-8
Ceiling 0.11 ppmCeiling 0.29
mg/m3
STEL 0.29mg/m3
STEL 0.11 ppm
Ceiling 0.11 ppmCeiling 0.29
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
KTD 0.11 ppmKTD 0.29 mg/m3
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: Clear LiquidColor: ClearOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Water solubility: Freely solubleBoiling point/range: No information available.
Company: Janssen Diagnostics, LLC
Not applicable.
Product code: 7900001/4771
pH:
Product name: Cell Fixative
7.5
Page 3 of 6
Flash point:
10. STABILITY AND REACTIVITYHazardous polymerization: Hazardous polymerization does not occur.
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: Sodium Azide is harmful to aquatic life at low concentrations. May cause long-term adverse
effects in the aquatic environment
13. DISPOSAL CONSIDERATIONS
Acute toxicity
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Sodium Azide (0.1%)26628-22-8
27 mg/kg (Rat) 20 mg/kg (Rabbit)50 mg/kg (Rat)
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4771Product name: Cell Fixative Page 4 of 6
Genotoxic effects Not available.
May cause sensitization by skin contact.May cause skin irritation.May be harmful if absorbed through skin
Target Organ(s) Skin
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion Harmful if swallowed.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
13. DISPOSAL CONSIDERATIONSWaste from residues / unused products: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Contaminated packaging: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xn - Harmful.
R -phrase(s)R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.S -phrase(s)S28 - After contact with skin, wash immediately with plenty of water and soap.S46 - If swallowed, seek medical advice immediately and show this container or label.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
Sodium Azide (0.1%)26628-22-8
X X (1)-482 X X KE-31357
Serum Albumin (0.1%)9048-46-8
X X X X KE-05-0011
Components Australia HazardousSubstances List
China Banned orSeverely Restricted
Toxic Chemicals List
Korea Non-ToxicChemicals List
Korea RestrictedSubstances Data
Phillipines PriorityChemical List (PCL)
Sodium Azide (0.1%)26628-22-8
X
Components Thailand More DangerousChemicals List
Thailand Hazardous SubstancesList
Thailand Dangerous ChemicalsList
Sodium Azide (0.1%)26628-22-8
Listed.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
Product code: 7900001/4771Product name: Cell FixativeCompany: Janssen Diagnostics, LLC
Page 5 of 6
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Cell FixativeCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4771
Material Safety Data SheetProduct code: 7900001/4772Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Nucleic Acid DyeProduct code: 7900001/4772Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: May cause sensitization by skin contact.May cause eye/skin irritation.
Indication of danger: Xi - Irritant.
Most important hazardsRisk Phrase R43 - May cause sensitization by skin contact.
Product code: 7900001/4772Product name: Nucleic Acid DyeCompany: Janssen Diagnostics, LLC
Page 1 of 5
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationProClin 300 PRO300 0.05 C;R34
N;R51-53R43
Xn;R20/21/22
4. FIRST AID MEASURES
Eye contact: Rinse immediately with plenty of water, also under the eyelids. If eye irritation persists, consulta specialist.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth with water. Do notinduce vomiting without medical advice. Consult a physician if necessary.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product name: Nucleic Acid DyeCompany: Janssen Diagnostics, LLC
Page 2 of 5Product code: 7900001/4772
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components CAS Number Weight % J&J - OEL (TWA- 8 hr)
J&J - OEL(STEL)
J&J - OEL(Ceiling)
J&J - PBOEL
ProClin 300 PRO300 0.05 Category 4
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: Clear to Pale yellow liquidColor: Clear to Pale yellowOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Hazardous polymerization: Hazardous polymerization does not occur.
Boiling point/range: No information available.Not applicable.pH:
Company: Janssen Diagnostics, LLC
7.5
Product code: 7900001/4772
Flash point:
Product name: Nucleic Acid Dye
Water solubility:
Page 3 of 5
Freely soluble
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: This product has no known aquatic toxicological effects.
13. DISPOSAL CONSIDERATIONS
Waste from residues / unused products: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Contaminated packaging: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
ProClin 300 (0.05%)PRO300
3600 mg/kg >3500 mg/kg 37
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4772
Acute toxicity
Product name: Nucleic Acid Dye Page 4 of 5
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion No effects expected. Ingestion may causegastrointestinal irritation, nausea, vomiting anddiahrrea.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
Genotoxic effects Not available.
May cause skin irritation.May cause sensitization by skin contact.
Target Organ(s) Skin
13. DISPOSAL CONSIDERATIONS
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xi - Irritant.
R -phrase(s)R43 - May cause sensitization by skin contact.S -phrase(s)S24 - Avoid contact with skin.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product code: 7900001/4772Product name: Nucleic Acid DyeCompany: Janssen Diagnostics, LLC
Page 5 of 5
Material Safety Data SheetProduct code: 7900001/4773Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Capture Enhancement ReagentProduct code: 7900001/4773Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Harmful if swallowed.May be harmful in contact with skin.Product contains animal-derived material.May cause sensitization by skin contact.This product may cause eye irritation.
Indication of danger: Xn - Harmful.
Product name: Capture Enhancement ReagentCompany: Janssen Diagnostics, LLC
Page 1 of 6Product code: 7900001/4773
Most important hazardsRisk Phrase R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSerum Albumin 9048-46-8 0.5 232-936-2Sodium Azide 26628-22-8 0.1 247-852-1 T+;R28-32
N;R50-53
4. FIRST AID MEASURES
Eye contact: In the case of contact with eyes, rinse immediately with plenty of water for 15 minutes and seekmedical attention.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth. Do not induce vomitingwithout medical advice. Obtain medical attention.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product code: 7900001/4773Product name: Capture Enhancement ReagentCompany: Janssen Diagnostics, LLC
Page 2 of 6
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components Australia Hong Kong Japan India Korea Malaysia ChinaSodium Azide (0.1%)26628-22-8
Ceiling 0.1 ppmCeiling 0.3
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
MAC 0.3 mg/m3
Components New Zealand Philippines Singapore Taiwan Thailand ACGIH OEL IndonesiaSodium Azide (0.1%)26628-22-8
Ceiling 0.11 ppmCeiling 0.29
mg/m3
STEL 0.29mg/m3
STEL 0.11 ppm
Ceiling 0.11 ppmCeiling 0.29
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
KTD 0.11 ppmKTD 0.29 mg/m3
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: LiquidColor: various
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Hazardous polymerization: Hazardous polymerization does not occur.
Boiling point/range: No information available.
Company: Janssen Diagnostics, LLC
Not applicable.
Product code: 7900001/4773
pH:
Product name: Capture Enhancement Reagent
Not applicable
Page 3 of 6
Flash point:
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: Sodium Azide is harmful to aquatic life at low concentrations. May cause long-term adverse
effects in the aquatic environment
13. DISPOSAL CONSIDERATIONS
Waste from residues / unused products: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Sodium Azide (0.1%)26628-22-8
27 mg/kg (Rat) 20 mg/kg (Rabbit)50 mg/kg (Rat)
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4773Product name: Capture Enhancement Reagent Page 4 of 6
Acute toxicity
May cause sensitization by skin contact.May cause skin irritation.May be harmful if absorbed through skin
Target Organ(s) Skin
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion Harmful if swallowed.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
Genotoxic effects Not available.
13. DISPOSAL CONSIDERATIONSContaminated packaging: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xn - Harmful.
R -phrase(s)R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.S -phrase(s)S28 - After contact with skin, wash immediately with plenty of water and soap.S46 - If swallowed, seek medical advice immediately and show this container or label.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
Serum Albumin (0.5%)9048-46-8
X X X X KE-05-0011
Sodium Azide (0.1%)26628-22-8
X X (1)-482 X X KE-31357
Components Australia HazardousSubstances List
China Banned orSeverely Restricted
Toxic Chemicals List
Korea Non-ToxicChemicals List
Korea RestrictedSubstances Data
Phillipines PriorityChemical List (PCL)
Sodium Azide (0.1%)26628-22-8
X
Components Thailand More DangerousChemicals List
Thailand Hazardous SubstancesList
Thailand Dangerous ChemicalsList
Sodium Azide (0.1%)26628-22-8
Listed.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Product code: 7900001/4773Product name: Capture Enhancement ReagentCompany: Janssen Diagnostics, LLC
Page 5 of 6
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Capture Enhancement ReagentCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4773
Material Safety Data SheetProduct code: 7900001/4774Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Dilution BufferProduct code: 7900001/4774Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Harmful if swallowed.May be harmful in contact with skin.Product contains animal-derived material.May cause sensitization by skin contact.This product may cause eye irritation.
Indication of danger: Xn - Harmful.
Product name: Dilution BufferCompany: Janssen Diagnostics, LLC
Page 1 of 6Product code: 7900001/4774
Most important hazardsRisk Phrase R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSerum Albumin 9048-46-8 0.5 232-936-2Sodium Azide 26628-22-8 0.1 247-852-1 T+;R28-32
N;R50-53
4. FIRST AID MEASURES
Eye contact: In the case of contact with eyes, rinse immediately with plenty of water for 15 minutes and seekmedical attention.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth. Do not induce vomitingwithout medical advice. Obtain medical attention.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product code: 7900001/4774Product name: Dilution BufferCompany: Janssen Diagnostics, LLC
Page 2 of 6
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components Australia Hong Kong Japan India Korea Malaysia ChinaSodium Azide (0.1%)26628-22-8
Ceiling 0.1 ppmCeiling 0.3
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
MAC 0.3 mg/m3
Components New Zealand Philippines Singapore Taiwan Thailand ACGIH OEL IndonesiaSodium Azide (0.1%)26628-22-8
Ceiling 0.11 ppmCeiling 0.29
mg/m3
STEL 0.29mg/m3
STEL 0.11 ppm
Ceiling 0.11 ppmCeiling 0.29
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
KTD 0.11 ppmKTD 0.29 mg/m3
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: Clear LiquidColor: ClearOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Water solubility: Freely solubleBoiling point/range: No information available.
Company: Janssen Diagnostics, LLC
Not applicable.
Product code: 7900001/4774
pH:
Product name: Dilution Buffer
7.5
Page 3 of 6
Flash point:
10. STABILITY AND REACTIVITYHazardous polymerization: Hazardous polymerization does not occur.
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: Sodium Azide is harmful to aquatic life at low concentrations. May cause long-term adverse
effects in the aquatic environment
13. DISPOSAL CONSIDERATIONS
Acute toxicity
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Sodium Azide (0.1%)26628-22-8
27 mg/kg (Rat) 20 mg/kg (Rabbit)50 mg/kg (Rat)
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4774Product name: Dilution Buffer Page 4 of 6
Genotoxic effects Not available.
May cause sensitization by skin contact.May cause skin irritation.May be harmful if absorbed through skin
Target Organ(s) Skin
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion Harmful if swallowed.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
13. DISPOSAL CONSIDERATIONSWaste from residues / unused products: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Contaminated packaging: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xn - Harmful.
R -phrase(s)R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.S -phrase(s)S28 - After contact with skin, wash immediately with plenty of water and soap.S46 - If swallowed, seek medical advice immediately and show this container or label.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
EDTA (0 - 10%%) X X (2)-1265 X X
Serum Albumin (0.5%)9048-46-8
X X X X KE-05-0011
Sodium Azide (0.1%)26628-22-8
X X (1)-482 X X KE-31357
Components Japan IndustrialSafety & Health
Law (ISHL)Listing
JapanPharmacopoeia
List:
Japan class iispecifiedchemical
substance -:
Japandesignatedchemical
substance -:
Japan ISHLProhibited
SubstancesData
Japan DeleteriousSubstances - Main
Law List
EDTA (0 - 10%%) X
Components Australia HazardousSubstances List
China Banned orSeverely Restricted
Toxic Chemicals List
Korea Non-ToxicChemicals List
Korea RestrictedSubstances Data
Phillipines PriorityChemical List (PCL)
Sodium Azide (0.1%)26628-22-8
X
Components Thailand More DangerousChemicals List
Thailand Hazardous SubstancesList
Thailand Dangerous ChemicalsList
Sodium Azide (0.1%)26628-22-8
Listed.
16. OTHER INFORMATION
Product code: 7900001/4774Product name: Dilution BufferCompany: Janssen Diagnostics, LLC
Page 5 of 6
16. OTHER INFORMATIONThis data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Dilution BufferCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4774
Material Safety Data SheetProduct code: 7900001/4776Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Anti-EpCAM FerrofluidProduct code: 7900001/4776Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Product contains animal-derived material.May cause sensitization by skin contact.May cause eye/skin irritation.
Indication of danger: Xi - Irritant.
Most important hazards
Product code: 7900001/4776Product name: Anti-EpCAM FerrofluidCompany: Janssen Diagnostics, LLC
Page 1 of 6
Risk Phrase R43 - May cause sensitization by skin contact.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product contains animal-derived material.
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSerum Albumin 9048-46-8 - 232-936-2ProClin 300 PRO300 0.05 C;R34
N;R51-53R43
Xn;R20/21/22
4. FIRST AID MEASURES
Eye contact: Rinse immediately with plenty of water, also under the eyelids. If eye irritation persists, consulta specialist.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth with water. Do notinduce vomiting without medical advice. Consult a physician if necessary.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product name: Anti-EpCAM FerrofluidCompany: Janssen Diagnostics, LLC
Page 2 of 6Product code: 7900001/4776
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components CAS Number Weight % J&J - OEL (TWA- 8 hr)
J&J - OEL(STEL)
J&J - OEL(Ceiling)
J&J - PBOEL
ProClin 300 PRO300 0.05 Category 4
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: Brown LiquidColor: BrownOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.Acid chlorides.Acid anhydrides.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Hazardous polymerization: Hazardous polymerization does not occur.
Boiling point/range: No information available.Not applicable.pH:
Company: Janssen Diagnostics, LLC
Not applicable
Product code: 7900001/4776
Flash point:
Product name: Anti-EpCAM Ferrofluid
Water solubility:
Page 3 of 6
Freely soluble
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: This product has no known aquatic toxicological effects.
13. DISPOSAL CONSIDERATIONS
Waste from residues / unused products: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Acute toxicity
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Water (99.6%)7732-18-5
90090
ProClin 300 (0.05%)PRO300
3600 mg/kg >3500 mg/kg 37
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4776Product name: Anti-EpCAM Ferrofluid Page 4 of 6
Target Organ(s) Skin
Ingestion No effects expected. Ingestion may causegastrointestinal irritation, nausea, vomiting anddiahrrea.
Reproductive effects Not available.
Skin contact
Inhalation
Developmental effects Not available.
May cause irritation of respiratory tract.
May cause skin irritation.May cause sensitization by skin contact.
Carcinogenic effects Not available.
Eye contact May cause eye irritation.
Genotoxic effects Not available.
13. DISPOSAL CONSIDERATIONSContaminated packaging: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xi - Irritant.
R -phrase(s)R43 - May cause sensitization by skin contact.S -phrase(s)S24 - Avoid contact with skin.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
Water (99.6%)7732-18-5
X X X X KE-35400
Serum Albumin (-%)9048-46-8
X X X X KE-05-0011
Components Japan IndustrialSafety & Health
Law (ISHL)Listing
JapanPharmacopoeia
List:
Japan class iispecifiedchemical
substance -:
Japandesignatedchemical
substance -:
Japan ISHLProhibited
SubstancesData
Japan DeleteriousSubstances - Main
Law List
Water (99.6%)7732-18-5
X
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Product code: 7900001/4776Product name: Anti-EpCAM FerrofluidCompany: Janssen Diagnostics, LLC
Page 5 of 6
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Anti-EpCAM FerrofluidCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4776
Material Safety Data SheetProduct code: 7900001/4777Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Staining ReagentProduct code: 7900001/4777Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Harmful if swallowed.May be harmful in contact with skin.Product contains animal-derived material.May cause sensitization by skin contact.This product may cause eye irritation.
Indication of danger: Xn - Harmful.
Product name: Staining ReagentCompany: Janssen Diagnostics, LLC
Page 1 of 6Product code: 7900001/4777
Most important hazardsRisk Phrase R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSerum Albumin 9048-46-8 0.5 232-936-2Sodium Azide 26628-22-8 0.1 247-852-1 T+;R28-32
N;R50-53
4. FIRST AID MEASURES
Eye contact: In the case of contact with eyes, rinse immediately with plenty of water for 15 minutes and seekmedical attention.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth. Do not induce vomitingwithout medical advice. Obtain medical attention.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product code: 7900001/4777Product name: Staining ReagentCompany: Janssen Diagnostics, LLC
Page 2 of 6
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components Australia Hong Kong Japan India Korea Malaysia ChinaSodium Azide (0.1%)26628-22-8
Ceiling 0.1 ppmCeiling 0.3
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
MAC 0.3 mg/m3
Components New Zealand Philippines Singapore Taiwan Thailand ACGIH OEL IndonesiaSodium Azide (0.1%)26628-22-8
Ceiling 0.11 ppmCeiling 0.29
mg/m3
STEL 0.29mg/m3
STEL 0.11 ppm
Ceiling 0.11 ppmCeiling 0.29
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
KTD 0.11 ppmKTD 0.29 mg/m3
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: LiquidColor: Clear Pinkish-purpleOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Water solubility: Freely solubleBoiling point/range: No information available.
Company: Janssen Diagnostics, LLC
Not applicable.
Product code: 7900001/4777
pH:
Product name: Staining Reagent
7.5
Page 3 of 6
Flash point:
10. STABILITY AND REACTIVITYHazardous polymerization: Hazardous polymerization does not occur.
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: Sodium Azide is harmful to aquatic life at low concentrations. May cause long-term adverse
effects in the aquatic environment
13. DISPOSAL CONSIDERATIONS
Acute toxicity
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Sodium Azide (0.1%)26628-22-8
27 mg/kg (Rat) 20 mg/kg (Rabbit)50 mg/kg (Rat)
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4777Product name: Staining Reagent Page 4 of 6
Genotoxic effects Not available.
May cause sensitization by skin contact.May cause skin irritation.May be harmful if absorbed through skin
Target Organ(s) Skin
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion Harmful if swallowed.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
13. DISPOSAL CONSIDERATIONSWaste from residues / unused products: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Contaminated packaging: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xn - Harmful.
R -phrase(s)R22 - Harmful if swallowed.R43 - May cause sensitization by skin contact.S -phrase(s)S28 - After contact with skin, wash immediately with plenty of water and soap.S46 - If swallowed, seek medical advice immediately and show this container or label.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
Serum Albumin (0.5%)9048-46-8
X X X X KE-05-0011
Sodium Azide (0.1%)26628-22-8
X X (1)-482 X X KE-31357
Components Australia HazardousSubstances List
China Banned orSeverely Restricted
Toxic Chemicals List
Korea Non-ToxicChemicals List
Korea RestrictedSubstances Data
Phillipines PriorityChemical List (PCL)
Sodium Azide (0.1%)26628-22-8
X
Components Thailand More DangerousChemicals List
Thailand Hazardous SubstancesList
Thailand Dangerous ChemicalsList
Sodium Azide (0.1%)26628-22-8
Listed.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
Product code: 7900001/4777Product name: Staining ReagentCompany: Janssen Diagnostics, LLC
Page 5 of 6
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Staining ReagentCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4777
Material Safety Data SheetProduct code: 7900001/4778Revision date: 03-20-20141. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE
COMPANY/UNDERTAKING
Supplier:Janssen Diagnostics, LLC700 US Highway Route 202 SouthRaritan, NJ 08869
E-mail address [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] - [email protected] Ireland - [email protected] - [email protected]
Customer service telephone: (800) 421-3311Emergency telephone number: (800) 424-9300 ChemTrec (24 hours)
Product name: Permeabilization ReagentProduct code: 7900001/4778Identified use: Reagent
2. HAZARDS IDENTIFICATION
General hazard information: Harmful if swallowed.May be harmful in contact with skin.This product may cause eye irritation.
Indication of danger: Xn - Harmful.
Most important hazards
Product code: 7900001/4778Product name: Permeabilization ReagentCompany: Janssen Diagnostics, LLC
Page 1 of 6
Risk Phrase R22 - Harmful if swallowed.
Carcinogenicity rating:Johnson & Johnson: None.European Union: None.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Components CAS Number Weight % Synonyms EINECS-No. ClassificationSodium Azide 26628-22-8 0.1 247-852-1 T+;R28-32
N;R50-53
4. FIRST AID MEASURES
Eye contact: In the case of contact with eyes, rinse immediately with plenty of water for 15 minutes and seekmedical attention.
Skin contact: Wash off immediately with soap and plenty of water. Wash contaminated clothing before re-use. In the case of skin irritation or allergic reactions see a physician.
Ingestion: Never give anything by mouth to an unconscious person. Rinse mouth. Do not induce vomitingwithout medical advice. Obtain medical attention.
Inhalation: Move to fresh air immediately. If experiencing difficulty breathing, seek medical attention.
5. FIRE-FIGHTING MEASURESSuitable extinguishing media: Use any extinguishing media which is suitable for the surrounding
fire.
Extinguishing media which must not be used for safetyreasons:
None.
Special exposure hazards arising from the substance orpreparation itself, combustion products, resulting gases:
None reasonably foreseeable.
Special protective equipment for firefighters: Wear self-contained breathing apparatus and protective suit.
Combustion products or resulting gases: None.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Ensure adequate ventilation. Wear suitable gloves and eye/face protectionEnvironmental precautions: Do not allow material to contaminate ground water system.Methods for cleaning up: Absorb spill with inert material (e.g. dry sand or earth), then place in a chemical waste
container.Clean contaminated surface thoroughly.
Product name: Permeabilization ReagentCompany: Janssen Diagnostics, LLC
Page 2 of 6Product code: 7900001/4778
7. HANDLING AND STORAGE
Handling:Technical measures/precautions: Use only in area provided with appropriate exhaust ventilation.Safe handling advice: Avoid contact with skin, eyes and clothing. Wash hands before
breaks and immediately after handling the product. Avoid formationof aerosols. Avoid breathing vapors or mist.
Storage:Technical measures/storage conditions: Keep containers tightly closed. Store according to labeled
instructions. Keep at temperatures between 2 and 8°CIncompatible products: Oxidizing agents
Specific use(s): None under normal use.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Components Australia Hong Kong Japan India Korea Malaysia ChinaSodium Azide (0.1%)26628-22-8
Ceiling 0.1 ppmCeiling 0.3
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
MAC 0.3 mg/m3
Components New Zealand Philippines Singapore Taiwan Thailand ACGIH OEL IndonesiaSodium Azide (0.1%)26628-22-8
Ceiling 0.11 ppmCeiling 0.29
mg/m3
STEL 0.29mg/m3
STEL 0.11 ppm
Ceiling 0.11 ppmCeiling 0.29
mg/m3
Ceiling 0.29mg/m3
Ceiling 0.11 ppm
KTD 0.11 ppmKTD 0.29 mg/m3
Engineering controls: Ensure adequate ventilation. Eye baths, washing facilities, and safety shower.
Eye protection: Eye and face protection recommended when manufacturing product.
Hand protection: Wear disposable gloves while handling kit reagents. Thoroughly wash hands afterwards.
Respiratory protection: Respiratory protection dependent on airborne exposures.
Skin and body protection: Skin protection recommended when manufacturing product.
9. PHYSICAL AND CHEMICAL PROPERTIES
General Information
Physical state: LiquidAppearance: Clear LiquidColor: ClearOdor: Odorless
Important Health Safety and Environmental Information
Other information
Explosivity: None.
10. STABILITY AND REACTIVITY
Chemical stability: Stable.Materials to avoid: Strong acids and strong bases.
Reducing agents.Stay away from strong oxidizing agents.
Conditions to avoid: Hazardous decomposition products may be produced when the recommended processingtemperatures or times are exceeded.
Water solubility: Freely solubleBoiling point/range: No information available.
Company: Janssen Diagnostics, LLC
Not applicable.
Product code: 7900001/4778
pH:
Product name: Permeabilization Reagent
7.5
Page 3 of 6
Flash point:
10. STABILITY AND REACTIVITYHazardous polymerization: Hazardous polymerization does not occur.
11. TOXICOLOGICAL INFORMATION
12. ECOLOGICAL INFORMATION
EcotoxicityEcotoxicity effects: This product has no known eco-toxicological effects.Aquatic toxicity effects: Sodium Azide is harmful to aquatic life at low concentrations. May cause long-term adverse
effects in the aquatic environment
13. DISPOSAL CONSIDERATIONS
Waste from residues / unused products: Waste disposal must be in accordance with appropriate US,Federal, State and International regulations.This product, if unaltered by use, may be disposed of by treatmentat a permitted facility or as advised by your local hazardous wasteregulatory authority.
Specific effects
Components LD50 Oral LD50 Dermal LC50 (mg/m3)Inhalation
LC50 (ppm) Inhalation
Sodium Azide (0.1%)26628-22-8
27 mg/kg (Rat) 20 mg/kg (Rabbit)50 mg/kg (Rat)
Sub-Chronic/Chronic ToxicityNo repeat dose data available.
Company: Janssen Diagnostics, LLC Product code: 7900001/4778Product name: Permeabilization Reagent Page 4 of 6
Acute toxicity
May cause skin irritation.May be harmful if absorbed through skin
Target Organ(s) No significant organ toxicity expected.
Eye contact May cause eye irritation.
Reproductive effects Not available.Developmental effects Not available.
Ingestion Harmful if swallowed.
Carcinogenic effects Not available.
Skin contact
Inhalation May cause irritation of respiratory tract.
Genotoxic effects Not available.
13. DISPOSAL CONSIDERATIONSContaminated packaging: Waste disposal must be in accordance with appropriate US,
Federal, State and International regulations.
14. TRANSPORT INFORMATION
Product not regulated by DOT, IATA/ICAO, IMO/IMDG, ADR/RID, or TDG.
15. REGULATORY INFORMATION
Indication of danger: Xn - Harmful.
R -phrase(s)R22 - Harmful if swallowed.S -phrase(s)S28 - After contact with skin, wash immediately with plenty of water and soap.S46 - If swallowed, seek medical advice immediately and show this container or label.
Components Australia (AICS)List:
New Zealand Japan Inventoryof Existing &
New ChemicalSubstances
(ENCS)
China InventoryList:
Philippines(PICCS) List:
Korea Inventory(KECL) List:
Sodium Azide (0.1%)26628-22-8
X X (1)-482 X X KE-31357
Components Australia HazardousSubstances List
China Banned orSeverely Restricted
Toxic Chemicals List
Korea Non-ToxicChemicals List
Korea RestrictedSubstances Data
Phillipines PriorityChemical List (PCL)
Sodium Azide (0.1%)26628-22-8
X
Components Thailand More DangerousChemicals List
Thailand Hazardous SubstancesList
Thailand Dangerous ChemicalsList
Sodium Azide (0.1%)26628-22-8
Listed.
16. OTHER INFORMATION
This data sheet contains changes from the previous version in section(s):None.
Additional advice: Australian Poisons Information Centre24 Hour Service: - 13 11 26Police or Fire Brigade: - 0000 (exchange): - 1100
Literary reference: The values set up in the table for Content % are derived from the 28th Adaption of Annex I andChips III for calculating the formulation. C represents concentration.
MSDS Format: Asian Pacific FormatThis Material Safety Data Sheet was prepared in accordance with Regulation JIS Z7250 of theOccupational Safety and Health Regulation.
Product code: 7900001/4778Product name: Permeabilization ReagentCompany: Janssen Diagnostics, LLC
Page 5 of 6
Disclaimer:The information and recommendations contained herein are based upon tests believed to be reliable. However, Johnson and Johnsondoes not guarantee their accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY,WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, ORTHE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage may berequired. Johnson and Johnson assumes no responsibility for results obtained or for incidental or consequential damages, includinglost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made orimplied.
End of Safety Data Sheet
Product name: Permeabilization ReagentCompany: Janssen Diagnostics, LLC
Page 6 of 6Product code: 7900001/4778