RH ARKITEKTER OKTOBER 2014

MASTERPLAN

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WHO WE ARE

RH ARKITEKTER is dedicated to the pharmaceutical and biotechnology industries, education and health care. We are experts in the design of clean rooms classified by GMP / ISO standard, and we have amongst others worked with Novo Nordisk, Biogen Idec, Bavarian Nordic, Leo Pharma, Lundbeck and Novozymes.

Since our foundation in 2001, we have been developing solutions for large international life science companies and institutions in the design of laboratories, production facilities, clean rooms, pilot plants, medical centers, hospitals, teaching - and university facilities both in Denmark and internationally.

With bright and inspiring architecture in the Nordic tradition, we create the optimal conditions for effective, inspiring and safe working and production environments.

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CONTENT

RH ARKITEKTER has experience with design of manufacturing, laboratory and office buildings in scale from the macro programming to master planning, space management and building design, room optimization and interior expression. Recently we have developed master plans for both Novo Nordisk and Leo Pharma.

Most of our projects around overall programming and master planning are confidential. Therefore this presentation is primarily a visual tour of our methodology on all the different levels. We use a systematic and analytic approach to our projects. For some, we have developed software applications in order to rationalize the project execution and also provide an improved overview. The software applications are an integral part of our methodology.

On the following pages you will also find a description of the contents of each phase. Each phase will contain a presentation of the tools that are used and also examples and case stories of projects where we have used them.

01MACRO / ANALySIS ANd PROgRAMMINgpage 04

02SITE / MASTER PLANpage 07

02BUILdINgpage 10

02ROOMSpage 13

02FURNITUREpage 17

01MACRO / ANALySISANd PROgRAMMINg

: Location - in order to find the right site, the customer must baLance the need for educated empLoyees with attractive price, water suppLy and great infrastructure as weLL as other key parameters.

: capacity - together with the customer we wiLL anaLyze and determine the need for space e.g. growth in the number of research scientists per year. this is converted to the needed squa-re meters per year for Laboratories and sup-port faciLities (cooLing, storage, gowning etc.)

: organization - anaLysis of departments or sec-tions that wiLL coLLaborate now and in the futu-re, and hence need to be Located near each other

: workfLow - anaLysis of current and future workfLow, automation degree and work env-ironment

: branding - understand what the customer wants to project in terms of corporate bran-ding, and how that is expressed through the buiLding in the architecture as weLL as the in-terior design.

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01MACRO / ANALySISANd PROgRAMMINg

RH ARKITEKTER has developed a software tool for the Danish Property Agency which is a part of the Climate, Energy and Building Ministry. The tool was originally used to register current layout and future programming of universities. www.UNILAB.dk UNILAB focuses on three work areas:

: Registration of current building mass and layout : Planning of future building layout: Idea catalogue

In addition to this RH ARKITEKTER has devel-oped another tool (KK Planner) for the Copen-hagen Municipality to develop environmentally friendly design. In this tool it is possible to map the environmental impact for building projects, set targets and search for inspiration on how to diminish the impact.

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01MACRO / ANALySISANd PROgRAMMINg

Together with engineering partners RH ARKITEK-TER has been in charge of programming and planning most of the newer large Danish uni-versity building projects. The customer is the Danish Science Ministry. Here’s a few project examples: : BIOVAF, DTU Life Science + Bioengineering, Technical University of Denmark : Niels Bohr Science Park, University of Copenhagen : Extension of the Panum complex, University of Copenhagen : Faculty of Health Sciences, Research facilities to the Institute for Biomedicine, Aarhus University,  : New research building, Roskilde University

02SITE /MASTERPLAN

a master pLan must ensure an optimaL co-herence between functions and buiLdings that must be tied together in a LogicaL in-frastructure.

: greenfieLds must be anaLyzed in order to take future use and authority require-ments into account

: current site usage must be anaLyzed in the same way, and the current buiLding mass must be registered and their usabi-Lity evaLuated

: new generic buiLding types are deveLo-ped and shouLd be pLaced or bound to-gether with the current buiLdings in an optimaL and harmonic structure

: phased deveLopment pLans are deveLoped

: the need for surrounding faciLities is caLcuLated (x m2 of this Laboratory cate-gory wiLL require y number of canteens, auditoriums, parking space etc.)

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02SITE /MASTERPLAN

RH ARKITEKTER has developed an interactive building portfolio management tool for Leo Pharma. The master plan is the foundation of the tool. By a simple click on a building the tool can tell you what projects are ongoing, who the project manager is and other information like budget and schedule. In this way it is easy to get an overview of all the ongoing projects on the site and see the impact on economy and sched-ule if a project is postponed or accelerated.

Furthermore RH ARKITEKTER has developed a tool for Novo Nordisk that is used when the registration of buildings has been completed. The Vision Lab Planner tool is used to illustrate where the different departments are located, the number of square meters they occupy. It is easy to see where different categories of labo-ratories and common areas are localized. Vision Lab Planner can be used for initial planning as well as for relocation planning.

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02SITE /MASTERPLAN

In 2013 RH ARKITEKTER completed the master plan for Novo Nordisk research facility center in Måløv, Denmark. We have been involved in the vast majority of the current laboratory build-ings on site. Currently there are around 2,000 research scientists working on a daily basis on the site. The master plan was updated to make room for further 3,000 scientists. The first stage will be to build 15,000 m2 chemistry and analy-sis laboratories. This stage is also designed by RH ARKITEKTER and is currently under con-struction.

Another example of a master plan is the one RH ARKITEKTER has completed for the Leo Pharma site in Ballerup, Denmark. This site also con-tains research and development, commercial manufacturing and administration buildings. RH ARKITEKTER has been the architects behind a multitude of different projects on the site in-cluding laboratories, GMP manufacturing, head-quarter for the top management, canteen etc.

03BUILdINg

as change is continuous, rh arkitekter deveLops a generic buiLding Layout with the customer. this wiLL minimize the impact of changes and reLocati-on Later on, as it wiLL be easy to convert offices to Laboratories. when the master pLan consists of predesigned generic buiLding types the road from decision to reaLization is very short.

in a worLd of change, time is aLways a criticaL factor when deveLoping a new faciLity. this is why we have deveLoped a concept for prefabri-cated Laboratories.

the buiLding moduLes are the size of a typicaL room. each moduLe wiLL be manufactured in a factory, where it wiLL be fuLLy furnished, with aLL instaLLations in pLace. this way it is easy to ensure a great work environment for the con-struction personneL, and a way to minimize the safety hazards that typicaLLy are great con-cerns during traditionaL construction projects. the buiLding moduLes are transported on spe-ciaL carriers directLy to the construction site, where they are instaLLed and ready for use. in order to aLign the architecture with the other buiLdings on site, a façade can be designed as a part of the moduLe or Later mounted on the site.

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03BUILdINg

For the Novo Nordisk site in Måløv we have de-veloped a generic building type we call DUPLO. Within the same building geometry the DUPLPO can be fitted with a series of different laboratory types or offices. The master plan for Site Måløv is a series of DUPLO buildings, that are combined by connecting buildings containing special func-tions like canteens, auditoriums, meeting facili-ties, administration, receptions etc.

For the planning of the pre-fabricated laboratory modules RH ARKITEKTER has developed another web based tool where buildings and rooms are ite-mized and then put into the virtual shopping basket. www.modulab.dk

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03BUILdINg

Here are some examples where we have used one or more of the different tools and systems.

Novo Nordisk Building E5 / F5. 8.000 m2 labora-tories, animal houses and offices. Generic bui-ling design was applied as this is a part of the strategy for the Master Plan in Måløv.

Novo Nordisk Building B7 3.400 m2 analysis la-boratories on site Måløv. The building consists of prefabricated building modules with a brick façade to match architecture the other buildings on the site.

Lundbeck 4.900 m2 multi flexible administration offices in Valby.

Leo Pharma 3.000 m2offices for the corporate management aligned with the master plan for the Ballerup site.

04ROOMS

the generic buiLding is designed with a room Layout that is divided by function into categories. afterwards the needed number of workspaces, equipment and supporting functions is caLcuLated based on customer key numbers as weLL as our experience. this aLso goes for the number of meeting rooms, rest rooms etc.

for each room it is the function and work-fLow within it that wiLL determine the type of buiLding moduLe. then room Layout is determined by the workfLow between the different rooms.

rh arkitekter is committed to ensuring a great work environment in Laboratories and offices. ergonomics, day Light, arti-ficiaL Lighting and aesthetic design can ensure a great work environment, and in-ternationaL studies has proven that it has a positive Long term effect on the empLoy-ee’s physicaL and psychoLogicaL heaLth.

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04THE ROOM

In order to facilitate the configuration of each laboratory RH ARKITEKTER has developed Vivid. It is an interactive tool, where each room in the generic building can be configured. It is possible to work with both furniture and installations all the way from the overall building level to a room level. All data is registered and can generate a list of furniture and installations. It is also a 3D visualization tool, in which the user in collabo-ration with the architect can pre-determine the guiding principles for the furnishing in each lab-oratory category.

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04THE ROOM /LAB

Top left: FeF Chemicals, Køge, DenmarkTop right: Novozymes, North Carolina, USALower Left: Novo Nordisk, E5 / F5, Måløv, DenmarkLower right: Novo Nordisk Research Center, NNST Beijing, China

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04THE ROOM /OFFICE

To the left: Lundbeck, The Agora Building, Valby, DenmarkTo the right: Novo Nordisk, E5F5, Denmark

05FURNITURE

rh arkitekter recommends furniture with these key characteristics:

: fLexibLe moduLes that are easy to move around or exchange different eLements of.

: easy access to instaLLations, aLso to add-ing new instaLLations

: great work environment. possibiLities of mechanicaLLy adjusting the height of tabLes and other work stations. integrat-ing work Light under cupboards or in the instaLLation bridge. acoustic paneLs to re-duce noise. transparency in order to en-sure overview and daiLy coLLaboration.

: a safe pLace to work, with surfaces that are easy to cLean and joint that can be gmo approved.

: an aestheticaL design. a Laboratory in use contains a Lot of equipment. a simpListic fur-niture design with a cLean and aestheticaLLy pLeasing visuaL expression creates a caLm am-bience and hence a good work environment.

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05FURNITURE

The Vivid planning tool, developed by RH ARKITEKTER, is used on the building, room and furniture level. All the furnishings can be con-figured in detail with all installations, surface requirements, elevation functions etc. The ar-chitect places the furnishings in close collabo-ration with the user. Each room is shown in 3D to provide the user with a better idea of what the room will look when it is build. This has proven to avoid unpleasant misunderstandings that oth-erwise are not discovered until the room is taken into use.

Furthermore Vivid automatically generates con-figuration item lists, which can be used to cal-culate the price.

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05FURNITURE

RH ARKITEKTER has designed a new laboratory system called VisionLab in close collaboration with Labflex. The concept is high standards for ergonomics, flexibility, accessibility to installa-tions and clean ability.

The cupboards are hung from an installation bridge, and the doors are made of glass in or-der to ensure as much transparency as possible in the room. The cupboards can be replaced by shelves or removed completely from the bridge to create space for equipment.

Lighting is installed in the bottom of the cup-boards and also in the installation bridge. The dynamic light can be controlled per work mod-ule in order to suit the individual user or work operation.

VisionLab is a well thought laboratory system that combines functionality with aesthetics and is compliant with regulatory GMO requirements.

Type A - High transparency: High portal with cupboards hanging underneath

Type B - Medium transparency: Low portal with cupboards standing on top

Type C - Lower transparency: Low portal with cupboards and all installations