mars imaging: biomedical 3d spectroscopic x-ray imaging anthony butler
TRANSCRIPT
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MARS Imaging:
Biomedical 3Dspectroscopic X-ray imaging
Anthony Butler
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Goal
To bring spectroscopic X-ray imaging
into medical use
X-ray Detector
Technology
Clinical
Application
Our team is bridging this gap
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Overview
X-raysource
Object PatternRecognition
System
Detector
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The Team Technical team
University of Canterbury
Clinical team University of Otago
International Partners Incl. CERN, Cambridge Uni and
Erlangen Uni
The company MARS Bioimaging Ltd
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Benefits of Spectral X-rays
Better image quality Less artefacts
eg. Around coronary artery stents
K-edge imaging Better use of contrast agents
eg. Less scanning
Intrinsic tissue contrast eg. Breast cancer from normal tissue
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Polychromatic Bone
Soft tissueGadolinium
Modelled using the 8 energy thresholds
Potential of full body imaging
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The MARS ScannerMedipix All Resolution System
Energy resolution
Spatial resolution
Temporal resolution
Desktop microCT (x-ray)-Small animal studies-Pathology studies
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MedipixSpectroscopic Photon Processing Detector
17 Institutes, 12 years
Hosted by CERN
We provide Test-bed for technology Application development First clinical experiments
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First MARS medical scan
Iodine contrast12 keV 17 keV 33 keV 42 keV
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Looks like a “traditional CT”
MARS has higher resolution
Results: Grey Scale Imaging
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12keV 17keV
33keV 42keV
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Results: Spectral Imaging
Iodine Non-iodine
Useful for heart and cancer imaging
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Results: Spectral Imaging
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Anthony Butler
Nick Cook (CDHB) Nanette Schleich (UC)Juergen Meyer (Physics UC)Peter Renau (UC Maths)Fred Ross (Electrical UC)Phil Bones (Electrical UC)Stephen Hemmingson (Physics UC)Ross Ritchie (Physics UC)Nigel Anderson (Radiology UO)Richard Heinz (Physics UC)Jonathan Selkirk (Physics UC)
MARS
Medipix All Resolution System
Phil Butler (Physics UC)Jochen Butzer (Physics UC)Markus Firsching (Erlangen)Henry Liu (UO Radiology)Richard Watts (Physics UC)Nicola Scott (Cardiology, UO)Raphael Grasset (HITLab UC)Dave van Leeuwen (Electrical UC)Tim Buckenham (Radiology UO)Rachel Cullens (CPIT / UO)Medipix Collaboration (CERN)