managing technologies · innovative technologies and strategies for a sustainable production,...

managing technologies

Corporate Report 2019

1

Contentp. 2 Origins

p. 3 Recent History

p. 4 Organization

p. 5 Current time

p. 6 Value proposal

p. 7 Connected to knowledge networks

p. 8 Multisector solutions

p. 10 Business Units

p. 13 Singular Initiatives

p. 14 Promoted Projects

p. 15 R+D+2i Projects

p.20 NotifiedInspectionBody

p. 21 Advanced Technology Solutions

p. 22 Leitat undertakes

p. 23 Summary of 2018 activities

p.29 Leitatinfigures2018

p. 32 Our commitment


1. What is Leitat?Leitat is a Technological Institute with the mission of collaborating with companies and other entities to create economic, social and sustainable value by R&D+2i projects and technology processes from innovation and creativity. Leitat is the brand of the private entity Acondicionamiento Tarrasense and is recognized by the Catalan Government (TECNIO) and by the Spanish Ministry of Economy and Competitiveness.

2. Who does Leitat belong to?Leitatisaprivatenon-profitassociation of industrials with own legal and patrimonial capacity established in 1906. Leitat performs its activity according to the current legislation, its articles of association and its Internal Regime Rules.

3. What does Leitat contribute with?Leitat, from dynamism and proximity,providesflexiblemanagement in an open innovation environment as collaboration and cooperation driving force for technology transfer and promoting the principles of professionalism, respect for people and environmental care, at the same time.

4. Why does Leitat improve competitiveness at industrial level?Because Leitat promotes the implementation of industrial innovation strengthening modernization of the productive structures and the development of new high technology value products and meets the changing needs of the global market.

5. How can Leitat solve the technological needs?Thanks to its technology solvency, Leitat keeps creating knowledge, developing talent and acquiring high technology equipment and facilities,sothatthespecificandtechnology needs of our customers can be met. 6. Why does Leitat perform in many different sectors?Because this allows that many technologies are applicable in different sectors obtaining moreprofitabilityoftechnology,generating and broadening new opportunities even in sectors never before interconnected and focusing its activity on these sectors: Transport, Building, Packaging, Textile, Energy, Environment, Food, Cosmetics, Detergency, Sport, Health, Pharmacy and Veterinary, Chemistry and Materials, Security and Sea sector.

7. How does Leitat collaborate with companies and institutions?Leitatfromexperienceandflexibil-ity, by signing collaboration agree-ments to join efforts to meet the in-dustrial technology challenges set out and promoting enterprising ca-pacity and technology transfer.

8. Which is Leitat experience in industrial cooperation?For more than 100 years ago, Leitat impacts on companies and other en-tities through the management of R+D+2i proposals (research, devel-opment and industrial innovation) leading or participating in strategic projects and generating actives and knowledge.

9. Which is the geographical ambit of action?As well as acting at domestic level, Leitat actively leads and participates in many projects and international collaboration nets including Europe-an partners and others from other areas with

convergent interests.

10. How become part of Leitat?Any individual or corporation may become partner of Leitat by making a formal request on the webpage: www.leitat.org/socio

In Leitat, innovation means meeting industrial technology challengeswithefficiencyandefficacy.

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RECENT HISTORYSUMMARY OF THE MOST OUTSTANDING

EVENTS OF RECENT YEARS

Summary of activities 2018: See page 22

2017

In 1906, a group of industrialists concerned about quality, certification and research in the wool textile sector decided to found a supporting association for competitiveness of companies named Acondicionamiento Tarrasense. Those industrialists knew how to anticipate needs for business collective solutions and laid the foundations of the current concept of Leitat.

Over the years and thanks to the work performed, the entity evolved both to the extension of its activities and to the name that is currently identified with the brand known as Leitat.

During these years, our vocation in offering services to companies and entities has remained unchanged, whereas the activities developed, the organization and our internal work system have changed significantly specializing in different knowledge areas allowing the search for the best technology solutions for companies.

The results obtained lately show that the bet developed by Leitat towards knowledge generation and transfer to the productive fabric is an effective model for economic growth in a fast, efficient and sustainable way, creating at the same time new areas and models for talent development and personal performance for all employees.

ORIGINS

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CURRENT TIMEMANAGING TECHNOLOGIESWe manage technologies to turn technological challenges into high Social, Environmental, Economic and Industrial value. Thanks to our great experience (since 1906) and our cooperation with several companies and organizations, we have been working with more than 45 countries and developing more than 215 projects. We have joined our efforts to do research and to reach the globalized and competitive market with Creativity, Innovation and Learning.

We are a cohesive link between the market and the research by acting with aflexibleandsmoothapproachrequiredbyourcustomers,bycomplyingwith market needs and by fostering changes aimed at:

• Enhancing Technology Entrepreneurship • Supporting open innovation with large companies and SMEs • Leading promoted projects and unique initiatives • Consolidating international cooperation as a value of technological networking

We promote staff specialized in Technology Transfer as it encourages the creation of cooperative and reliable company environments to reach a knowledge and talent development-based economy.

Byfocusingonourstakeholders'needs(customers,affiliates,partners,suppliers, public administration, partnerships, related businesses and enterprises), we keep on enhancing our institutional role of delivering services to companies, organizations and enterprises in compliance with our principles and values based on Management Excellence.

In this Corporate Report, we want to introduce the activities performed in 2017. The results achieved represent the value of the efforts made by those people working for Leitat in addition to our mindset, skills, engagement, commitment and responsibility.

We remain at your disposal with the aim of ensuring continued progress. Best regards

Wishing to keep on working forward together, we remain at your disposal.

Our warmest greetings,

Mr. Jordi William CarnesPresident

[email protected]

Mr. Joan ParraManaging Director

[email protected]


Board of DirectorsMembers of the Executive Committee in 2019:

President: Mr. Jordi William Carnes Ayats

Vice-president: Mr. Josep Armengol GiraltOn behalf of the INDUSTRIAL INSTITUTE OF TERRASSA

Executive Vice-president:Mr. Joan Parra Farré

Secretary:Mrs. Ana M. Santaulària MuxíNon member

Member:Mr. Salvador Maluquer TrepatRepresentative of COTTON PROCESSING TEXTILE INDUSTRIES ASSOCIATION

Member:Mr. Francesc Roca i LlonguerasRepresentative of FINISH, S.A.

Member:Mrs. Dolors Puig GasolRepresentative of TALENTUM ASSOCIATS, S.L.

Member:Mr. Xavier Torra BalcellsOn behalf of FUNDACIÓ EURECAT

Member:Sr. Joan Romero i CircunsOn behalf of ACCIÓ

ORGANIZATIONAcondicionamiento Tarrasense is a non-profit entity, with legal status and ownassets, incorporated in 1906. The company governs its activities according to Law 4 / 2008, dated on April 24, of the third book of the Spanish Civil Code on legal persons (DOGC number 5123, May 2), the Organic Law 1 / 2002 of March 22, regulating the right of association (BOE 73, March 26) and its Articles.

GOVERNING BODIESThe Association consists of 8 associate members coming from several complementary industrial sectors and business associations.The General Assembly is the major and sovereign body of the entity in which all members are represented. The Board has the authority to represent, lead and manage the Association. This body also implements the decisions taken by the General Assembly, in accordance with the regulations, instructions and guidelines established.

Organization chartFrom a traditional structure to a flexible and dynamic organization. We focus on work teams and projects based on cross-communication and definition of responsibilities with the goal of meeting the technological expectations of customers and society.

BUSINESS UNITS Applied Chemistry & Materials (ACM) Circular Economy (CE) Energy & Engineering (E+E) Health & Biomedicine (H&B)

SINGULAR INITIATIVES HEHScenter BIP

PROMOTED PROJECTS IAM 3D hub

ADVANCED TECHNOLOGICAL SOLUTIONS SCIENTIFIC AND TECHNICAL SERVICES Characterization of materials

NOTIFIED BODY Certificationsofpersonalprotectiveequipment(PPE) and building materials

INNOVATION Innovation and New Technologies

STRATEGIC AND SUPPORTING STRUCTURE Finance and Administration Corporate Management Projects Management

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MAIN INTERNATIONAL ORGANIZATIONS ARTEMIS ARTEMIS Industry Association BBI Biobased Industries Consortium CLEANSKY Clean Sky Joint Undertaking EARPA European Automotive Research Partners Association EARTO European Association of Research and Technological Organization EASN European Aeronautics Science Network EFFRA European Factories of the Future Research Association EMIRI AISBL Energy Materials Industrial Research Initiative ERRIN European Regions Research and Innovation Network EU ROBOTICS European Robotics Coordination Action NANOSAFETY CLUSTER European Nanosafety Cluster SETAC Society of Environmental Toxicology and Chemistry SPIRE Sustainable Process Industry through ResourceandEnergyEfficiency VISION2020 Vision2020: The Horizon Network

WAITRO World Association of Industrial and Technological Research Organizations

MAIN EUROPEAN TECHNOLOGY PLATFORMS AM PLATFORM Additive Manufacturing Platform EPoSS European Technology Platform on Smart Systems Integration ETP NANOMEDICINE The European Technology Platform on Nanomedicine EUMAT European Technology Platform on Advanced Engineering Materials and Technologies NANOFUTURES European initiative for sustainable development by Nanotechnologies NET!WORKS eMobility European Technology Platform PHOTONICS 21 European Technology Platform for photonics SMARTGRIDS Smart Grids European Technology Platform SUSCHEM European Technology Platform for Sustainable Chemistry TEXTRANET European Technology Platform for the future of textiles and clothing WSSTP Water Supply and Sanitation Technology Platform

CONNECTED TO KNOWLEDGE NETWORKSRecognizing that intellectual property is universal and it is developed and strengthened anywhere in the world, Leitat strongly believes and promotes the concept of "Open Innovation" as force of collaboration to provide an effective response to the technology challenges posed by customers.

ORGANIZATIONS AND PLATFORMS • SPANISH: 64 • INTERNATIONAL: 49 MAIN SPANISH ORGANIZATIONS ASEBIO Asociación Española de Bioempresas SecPhO Southern European Cluster of Photonics and Optics

MAIN SPANISH TECHNOLOGY PLATFORMS 3NEO Plataforma Tecnológica Española de Nuevos Materiales, Nuevas Propiedades y Nuevos Procesos de Tecnologías de Impresión e Industrias Afines CLÚSTER MAV Clúster de Materials Avançats de Catalunya FOTONICA 21 Plataforma Tecnológica Española de Fotónica FOTOPLAT Plataforma Tecnológica Española de Fotovoltaica HISPAROB Plata forma Tecnológica Española de Robótica MANU-KET Plataforma Tecnológica de Fabricación Avanzada MANU-KET MATERPLAT Plataforma Tecnológica Española de Materiales Avanzados y Nanomateriales NANOMED Plataforma Española de Nanomedicina PLANETIC Plataforma Tecnológica Española de los Sistemas con Inteligencia Integrada (Embedded Systems) PTE - HPC Plataforma Tecnológica Española de Hidrógeno y Pilas de Combustible PTEPA Plataforma Tecnológica Española de la Pesca y la Acuicultura

PTF4LS Plataforma Tecnológica Food For Life Spain

SUSCHEM-ES La Plataforma Tecnológica Española de Química Sostenible

Terrassa Vilanova del Camí

++ Dynamism We have a good organizational structure to be able toofferfastandefficientsolutionsthatareadaptable,responsible and transparent.

++ Proximity We establish good communication with our environment withaglobalperspective,confidentialityandcommitment.

++ CollaborationParticipation in R+D+2i projects by providing knowledge and experience, with economical and social return.

++ Cooperation We cooperate to create sustainable and innovative value and globally respond with competitiveness.

CORPORATIVE CULTURE

PRINCIPLES: Our bases are sustained on 3 Strategic Pillars to face challenges and achieve successful opportunities:

• TECHNOLOGY • TALENT • EXCELLENCE

VALUES: We integrate our customs, behavior, thinking and attitudes in 3 Dimensions of the Corporate Culture that generate competitive value:

• RESPECT • OVERCOMING • ENTHUSIASM

WE GIVE ANSWER with our value proposal:

MANAGINGTECHNOLOGIES

MISSION We manage technologies to create and transfer Social, Environmental, Economic and Industrial sustainable value for companies and entities through research and technology processes.

VISION

Be a referent at global level in managing innovative technologies and reinforcing people creativity and talent.

Decalogue of the Principles of the Management Policy of Leitat:

1. STRATEGY2. CORPORATIVE CULTURE3. LEADERSHIP4. CUSTOMER’S SATISFACTION5. COMMUNICATION6. PARTICIPATION7. TRAINING8. SECURITY9. ENVIRONMENT10. LAW

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COSMETICS • Advanced materials (micro and nanocapsules and nanomaterials)

• Formulation of cosmetics

• Test on consumers

• Eco labelling for cosmetic products

• Effectiveness studies and innovative claim support

•Securityprofileofingredientsandcosmeticformulations

• Screening, bioproduction of characterization of new cosmetic actives

• Models in vitro mix (cellular-microbiota)

• Design and development of components, products and equipment for the cosmetic industry

DETERGENCY• Study and development of new active ingredients

•Formulationandefficiencytestsofproducts

• Test on consumers

• Eco labelling for detergency products

• Applied microbiology, enzymatic activity

HEALTH• Advanced materials (polymers and biopolymers, bioadhesives, matching adhesives)

• Biosensors

• Microbiota as biomarker of wellbeing / disorders

• Biomarkers in blood, urine and saliva

• Design and development of products and diagnostic and prognostic tools, monitoring of illnesses, treatment and vaccines

PHARMACY AND VETERINARY • Assessment of therapeutic targets

•Mechanismsofactionanddrugsefficiencystudies

• ADMETox

• Cellular models and animal models

•Oncologic,inflammatory,autoimmuneanddermatologicindications

• Generation and production of monoclonal and recombinant antibodies

• Biomedicine and nanomedicine

• Drug discovery and development

• Design and development of components, products and equipment for the pharmaceutical industry

CHEMISTRY AND MATERIALS• Synthesis of nanomaterials and polymers

• Formulation of polymers, paints, inks, coating and building materials

• Surfaces treatment

• Nanosecurity, REACH

• Testing, analytic chemistry and accompanying to industrialization

•Tribologyandtribochemistry(cuttingfluids,emulsions,oils, lubricants and fats)

SECURITY• Design and assessment of personal protective equipment

• Nanosecurity

• Sensors and actuators

•Studyonefficiencyandsecurity

• Biosecurity: fast detection of toxic and infectious agents

• Advanced materials (smart inks, nanomaterials)

SEA• Prevention and mitigation of emergent pollutants in the sea (microplastics)

• Recycling of materials of the sea sector (boats, etc.)

• Sea pollution reduction

•Managementandvalorisationoffishingandportwaste

• Screening of microorganisms and bioproduction of natural products

MULTISECTORIAL SOLUTIONS to the technology needs of companies TRANSPORT• Industrial design and development of components and products

• Advanced Materials (polymers, adhesives, coating, nanomaterials, micro and nanocapsules)

• Advanced fabrication: IoT, collaborative/mobile robotics and additive manufacturing /3D Printing

• Tribology and tribochemistry

• Connected vehicle

• Treatment, disinfection and quality control of interior air

BUILDING• Advanced Materials (asphalts, cement, nanomaterials, micro and nanocapsules, smart materials)

• Smart integration of renewable energy

•EnergyEfficiency

PACKAGING• Development of Packaging projects

• Prototyping through additive manufacturing

• Inks and printed electronics

• Global support to industrialization, testing and products validation

• Advanced materials (polymers, nanomaterials, barrier materials, coatings, electronic inks, sensor inks, micro and nanocapsules)

• Packaging ecodesign

• Active packaging

TEXTILE• Technical / smart textiles, support to industrialization and testing

• New materials for technical textiles (biomaterials, polymeric materials)

• Design and development of products based on textile solutions

•Developmentofinks,finishingandapplicationof nanotechnology

•Textilefinishingwithadvancedfunctionalities(coatings,inks, dyes, nanomaterials, micro and nanocapsules)

•Spinning,weavingandfinishingprocessestopilotprocesses

ENERGY• Emerging solar technology photovoltaic / concentration

• Design and development of components and products for the photovoltaic industry and energy

• Energy harvesting & management

•Studiesonenergyefficiency,measurementandsavingsverification

• Energetic valorisation of wastes • New materials for batteries and energy collection (polymers, nanomaterials, coating, inks)

ENVIRONMENT•Treatment,reuseandefficientmanagementofliquidflows

• Soil restoration

• Treatment and control of air quality

• Treatment and valorisation of waste/subproducts

• Sensoring of emerging pollutants

•Advancedmaterials(nanomaterials,nanofibres)forfiltration and decontamination of water and air

• Studies on ecotoxicity and nanosecurity

• Sensors and biosensors for the detection of micropollutants

• Design and development of components and products for the Environment industries

• Life cycle assessment and ecodesign

FOOD• Screening and new alternative sources of ingredients (microalgae, insects, subproducts)

• Development and validation of active ingredients, functional food • Microencapsulation of new active principles

•Cellularmodelsforstudiesonefficiencyandbioavailabilityof actives

• Models in vivo/in vitro mix and models of humanized animals

• Study on microbiota

• Energetic metabolism and nutrition

• Formulation of new food products

• Quality control, allergens and intolerances: detection by fast sensors and cellular characterization

• Food security

• Sensorial assessment on aliments and studies on useful life • Design and development of components, products and equipment for the food industry

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Industrial research adding value, differentiation and innovation opportunities in the global markets.

Multidisciplinary teams with know-how and experience in different knowledge areas and disciplines

BUSINESS UNITS

+ HEALTH & BIOMEDICINE (H&B) + APPLIED CHEMISTRY & MATERIALS (ACM) + ENERGY & ENGINEERING (E+E) + CIRCULAR ECONOMY (CE)

SINGULAR INITIATIVES

+ HEHScenter Human & Environmental Health & Safety Center

+ BIP Barcelona Institute of Packaging

PROMOTED PROJECTS

+ IAM 3D hub International Advanced Manufacturing 3D Hub

+ PROCESS IMPROVEMENT + PRODUCTS IMPROVEMENT + CHANGE ADAPTATION + INNOVATION CAPACITY + COMPETITIVE IMPACT + SOCIAL IMPACT + INTERNATIONALIZATION + ECONOMIC RETURN

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HEALTH & BIOMEDICINE (H&B)Research lines: • Generation of polyclonal and monoclonal antibodies (mAb) on demand for basic research, diagnosis and therapeutic treatments.

• Genetic engineering of proteins and monoclonal antibodies: Recombinant Proteins, Antibody Drug Conjugates (ADC), VHH single domain (nano) antibodies, Bispecific Antibodies,Chimerization, Humanization, Fusion Proteins, Antibody fragments (Fab, scFv), and Biosimilars.

• In vitro cellular models to study efficacy, security, actionmechanisms, screening, synergies, bioanalytic, metabolomics, etc. of drugs, cosmetics healthy products, food regenerative and supplements.

• In vivo animalmodels to study efficacy, biodistribution, pre-Toxand Maximum Tolerated Dose, pre-PK, histology, etc. (oncology, inflammation,dermatology,sports,cellularandtissueregeneration,angiogenesis.

• In vivo animal models to study microbioma, disbiosis and human microbiota transplant. Collaboration in the development of probiotics and prebiotics for nutrition and treatment of illnesses.

• Design of biogenetic tools for the validation of therapeutic targets and diagnostic biomarkers: siRNA, hairpins of DNA, arrays analysis, etc.

We focus on therapy and diagnosis in areas and sectors as oncology, inflammation, dermatology, sports cellular and tissueregeneration, angiogenesis, etc, with activities in:

•Analysis of the therapeutic efficacy in new drugs: chemical,biologic, cellular or genetic, at molecular, biochemical, immunochemical, cellular and in animals of laboratory.

• Projects on drug-targeting and drug-delivery to improve drugs and other therapeutic applications.

• Development of new biologic drugs (antibodies, monoclonal and recombinant proteins) and improvement of them (chimerization, humanization, biosimilar, conjugation).

• Identification,validationandcharacterizationofnew therapeutictargets and diagnostic biomarkers. • Determination of new indications for commercialized drugs and in clinicalphase(reprofilling).

• Development of new and innovative tool for the diagnosis, prognostic and monitoring of the illnesses evolution and their treatment (monoclonal antibodies, kits ELISA, kits inmunohistological).

•Development of devices for clinics (lateral flow devices,biosensors).Ourdiagnosticsolutionsand thespecificbiosensorsare applicable in different industrial sectors as sports health, veterinary, food and environment.

• Bioanayitic and metabolomic services for in vitro and in vivo studies, using high resolution analytic techniques (chromatography, combined with mass spectrometry)

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APPLIED CHEMISTRY & MATERIALS (AC&M)Research lines:• Raw Materials. Study and synthesis of polymers and biopolymers, Resins, organic compounds, surfactants and oils. Synthesis and surface modification of metallic and ceramic nanomaterials,nanofibresandcarbonaceousstructures.Studyandmodificationofsurfactants, oils and fats.

• Design and Formulation. Formulation of paints, inks and functional coating. Processes of mixing of asphalt, concrete and cement. Formulation of products of detergency and cosmetics. Development of polymeric composites (nanocomposites, biocomposites) through extrusion and reactive extursion. Electrospinning of nanofibres and hollow fibres. Formulation ofcuttingfluids,oilsandfats.

• Processing and Application. Transformation of polymers through conventional techniques (injection, extrusion, blowing and blowing injection). Spinning processes. Plasma treatments and coating and paints application (spray, spin, coating, padding, wiper). Ink printing (screen printing, inkjet, pad printing). Textile and surface washing processes. Application of tribochemical products on metallic surfaces. Sol-gel treatments and application ofnanofibresbyelectrospinningsonsubstrates.

• Validation. Characterization of materials (mechanic properties, impact, barrier, antimicrobial, hardness, scratching resistance, adherence, fire resistance), validation tests in detergency andcleaning products, studies on stability of formulations, lubricity and corrosion studies for tribochemical products, consumers tests, smelling evaluations and ecolabel. Accelerated ageing tests.

Global and optimized projects for the development of new materials aimed at the main industrial sectors as transport, aeronautic, energy, textile, detergency, packaging and environment.

We carry on integral projects in the sector of applied chemistry and materials encompassing the entire scale of values and different phases of the productive processes: phases of synthesis, formulation of raw materials with pilot processes and performances of technology demonstrators that apply the developed materials to the new ones, as well as recyclability studies and useful life. We try to help industry to develop its projects from any stage of the value chain of applied chemistry and the materials with the aim of providing knowledge and innovation and generating a strong and powerful industrial tissue from the new products and processes developed.

BUSINESS UNITS

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+Photo_Electronics_Lab_Source_Archives_Leitat

ENERGY & ENGINEERING (E+E)Research lines:• Energy technologies of low carbon footprint: Design, assembling and characterization, control and integration of devices and energy systems (solar, power storage, bioelectrochemical systems, conversion of energy carriers).

• Smart Systems. Sensors, optical/electrochemistry biosensors, printed electronic components, Internet-of-Things industrial and communication.

• Robotics / manufacturing advanced processes. Collaborative, mobile and automatized robotics.

• Design and development of products and processes thanks to industrial design, simulation and multiphysic modeling tools.

Our activities improve industrial competitiveness, create knowledge and technology for the transition to clean energy & mobility as well as digital transformation. We deliver technological innovation to industrial sectors such as energy, transportation or manufacturing, with impacts on new products, manufacturing processes and/or business models. This activity focuses on:

• Technology research • Industrial design and development

A multidisciplinary team formed by physicists, chemists, electrochemists and engineers allows developing innovative projects from different perspectives provided with different laboratories specialized in their activity:

• Laboratory of electronics• Laboratory of robotics• Laboratory of energy• Equipment of manufacturing, assembling and printing of devices • Equipment of solar simulation and electrochemistry characterization • Equipment of processing and characterization of composites • Design tools CAD/CAE/CAM• Software of simulation, multiphysics • Useful life and pre-homologation tests, accelerated ageing

+Photo_Fermentation_in_Bioreactor_Source_Archives_Leitat

CIRCULAR ECONOMY (CE) Innovative technologies and strategies for a sustainable production, efficient management of the natural sources, optimums treatment and valorization of waste fluids.

Research lines:• Water treatment and reuse. Industrial wastewater,municipal water or process water, separation and purif ication technologies (membrane processes, product recovery), biotechnologies (bio electrochemical systems, Nature Based Solutions), oxidation technologies and disinfection (Advanced Oxidation Processes, electrochemical processes).

• Treatment and recovery of waste/by-products. Urban wastes, biomass, mixed or complex industrial waste, conditioning technology, transformation of waste into product (hydrolysis/extraction, bioconversion), energy recovery (anaerobic digestion, thermal processes, biochemical systems).

• Air treatment and air quality control. Indoor/outdoor air, chemical and microbiological control, dispersion models, treatment and disinfection technologies (photo catalysis, f iltration, adsorption).

• Biotechnologies and Bio economy. Bioprocesses and biocatalysts for sustainable production, enzymes as active ingredients, new natural assets, new microbial consortiums for industrial or environmental applications, agro biotechnology.

• Bio-resources and agro-food technologies. New alternative sources of active ingredients, development and validation of ingredients (extraction, functionalization, separation/purif ication), formulation and validation of new products, sustainable food processing, food safety.

• Sustainable Production. Combination of technology, sustainability and competitiveness through business models based on circular economy, strategies of industrial symbiosis and process ef f iciency.

• Eco-design and Life Cycle Analysis. Life Cycle Analysis (LCA) of products, services and processes, eco-design of products and eco-innovation of services and processes.

• Environmental Communication and Social Responsibility: Ecological labeling for products and services, environmental communication strategies, social responsibility, citizen awareness and participation.

BUSINESS UNITS

+Photo_ Nanosecurity_source_Archives_Leitat

HEHScenterHuman & Environmental Health & Safety Center www.hehscenter.comIt of fers two platforms with tools promoting the competitiveness of the industries that use nanotechnology:

• Through the implementation of more safety solutions during the design and development of their products

• Developing the chances of fered by nanotechnology in the medicine sector to improve life quality of people

NANOSAFETY PLATFORM HEHScenter is formed by a multidisciplinar team working in these research lines:

Consulting Services• Identificationandtransferoftheregulatoryexigencies/demandsinthefieldofnanosecurity

• Technical-legal advice on environmental law and industrial security. REACH Regulation, CLP, biocides…Diagnostics, action plans, registrationfiles

• Mapping of exposure assessment and characterization of the risk of the product life cycle

• Advice on the use of tools for the nanomaterials risk analysis

R&D activities: • Assessment of the exposure (human and environmental) to nanomaterials and development of technology solutions for the mitigation associated to nanotechnology (safe-by-design)

• Assessment on (Eco)toxicology: in vitro toxicology studies; studies on ADME in vitro; cellular internalization and sublocalization of nanomaterials; studies on toxicity; ecotoxicology studies in organisms of land and aqueous compartments according to the standardized tests by the OECD

• Risk assessment: Assessment on nanomaterials risks: development of methodologies/models according to the characteristics/specificbehaviour of the nanometarisl for their implementation in tools of risk assessment

Testing Services:• Physical-chemical characterization of nanomaterials and nanoestructured materials

• Identificationandmonitoringofnanoparticlesandcomplexmatrix

• Monitoring and characterization of exposure (human and environmental ) to nanomaterials

Training & Education:Training courses: Tools for risk analysis and models applied in the nanosecurity field: courses on the progress in the regulatoryframework and its future application in nanotechnology

PLATFORM FOR NANOTECHNOLOGY IN HEALTHCARE (R&D) Nanomedicine• Design and manufacture of nanocapsules to carry out active principles via derma and oral

• Design and synthesis of smart nanoparticle systems targeted and/or localized

• Physical and chemical characterization of the nanoparticle systems

• Functionalization of the surface of the nanoparticles systems with small molecules and biomolecules

• Studies on stability of the nanoparticles systems: temperature, storage time, formulation

• Studies on security

•Studiesonefficiency(invitroandinvivomodels)

Nanobiosensors• Design and manufacture of inorganic nanoparticles to be applied in biosensors

• Physical and chemical characterization of the nanoparticles

• Functionalization of the surface of the nanoparticles with small molecules and biomolecules

BIPBarcelona Institute of Packagingwww.barcelonapackaging.orgProgram supporting companies on innovation and development projects on Packaging and offering technical accompaniment in industrial implementation, looking for the best synergies between RD equipment and Leitat product engineering.

• Product Packaging Engineering. Development of new packaging projects from the design to manufacture. BIP software tools as CAM / CAD / CAE for the development of the new packaging projects embracing the product design and engineering.

• Validation and technical tests: The validation of new designs, materials, compatibility in the environment product-package and environment. BIP has testing equipment to analyze and evaluate the mechanical, chemical and physical-chemical parameters for all kind of packages.

• Analysis of quality assessment and of packaging behaviour

Packaging and reengineering. Re-design projects, optimization and standardization to improve the efficiency and performance ofthe production lines. Cost reduction program OCB (Optimums Cost Balance)

• Packaging and Logistics. Projects on logistics efficiency andvalidation,testsandassessmentonstorageandtransport.CodificationandIdentification

• Packaging and Ecodesign: Projects proposals for the design of sustainable packages, life cycle assessment and environmental re-engineering.

• Support to training. The program is supported by the University Politécnica of Catalonia for training and recycling of engineers and technicians capable of leading the new challenges of the sector of package engineering, packaging and conditioning of products within the current framework of the post graduate course Packaging Engineering: packages and packaging technology and specialization courses.

SINGULAR INITIATIVES

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+Photo Copyright Renishaw: All rights reserved. Image reproduced with the permission of Renishaw.

PROMOTED PROJECTS

IAM 3D hubInternational Advanced Manufacturing 3D Hubwww.iam3dhub.orgIAM3D arises with the aim of making it easier for companies the adoption of additive manufacture as an alternative way of producing. It is a common initiative by Leitat, HP, Renishaw and Coniex-Abrast to which other technology actors-suppliers of software, materials, post processed,validation,certificationandresearchorganizations-aswellastrainingentities–institutesanduniversities-andeconomicactors.The center offers single window services to all kind of companies, SMEs, large companies and of new creation, as well as non technology companies wishing to experience and try end to end integrated solutions of additive manufacture.

SERVICES:• Experimenting and testing: Generation of knowledge and trust. Advising, knowing the expert, Lab-day, use AM / 3DP, benchmark

and tests for the Product Development, DAFO additive manufacture, materials and processes selection. Practical workshop / Lab-Day.

• End to end solutions: With the aim of developing end to end solutions, the center offers “Living-Lab” for design, explore, experience and redefine new products in real scenarios. The center also has an incubator for final applications and pilotlines for the manufacture of components for the whole additive manufacturing chain and 3D printing on an industrial scale. Thevalidationandcertificationlabsclosethesolutioncycle.

• Business & mentoring: The services offered to the new companies are the following: technology assessment, identification ofemergingtechnologies,adoptionacceleration,marketresearch,commercialviabilitystudies,identificationofroutestomarket,definitionandevaluationofbusinessmodels,backupfinancingtonewbusiness,identificationofpartnersandcollaborators,IPprotection,IPlicenses, market introduction and sales strategies. The services offered for the adoption of AM solutions in an existing company are: evaluationofthematuritylevelofthecompanyfortheadoptionofAM/3DP,analysisoftheadoptionpotential,identificationandfacingoftechnicalchallengesallowingproductiononanindustrialscale,developmentofoperationprocedures,specificationsandstandards,design and execution strategies, simulation and validation of AM integration into factory level, development of the supplying chain, support on purchase-sale decisions and simulation and validation of AM integration at enterprise level.

• Training and education: Programas de capacitación industrial y formación profesional teórico-práctica a personal de empresa a lo largo de toda la cadena de valor. Talleres de formación de formadores. Así mismo ofrecerá un entorno ideal para la formación académica–másteroficial,doctoradoindustrial-eimplementacióndeprogramasSTEAM.

• R+D: R+D collaborative environment with the most powerful and proper resources to promote, strengthen and advice the technology supplierstosearchthespecificduringthewholevaluechainoftheindustry:design,materials,AM/3DPprocesses,post-processesand validation, creation and share of a research atmosphere to innovate and search into the additive manufacture technologies. It is definedasacollaborative,transparent,openandreliablewithproposalsandsharedresources.

R+D+2iOUTSTANDINGPROJECTS ONINDUSTRIAL RESEARCH

+ Industrial Innovation

+ Competitivity

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MINIMIZATION OF MICROFIBERS IN THE LIFE CYCLE OF TEXTILE PRODUCTSThe FIBERCLEAN project aims to obtain new solutions that will reduce the emission of microfibers through the entire value chain of manufacturing andmaintenance of fabrics and garments. The problem will be attacked from 2 different perspectives. First, research and development of new yarns, fabrics and finished products with properties that prevent the release ofmicrofibersduring several phases of the life cycle of the product or that allow to revalue them. Second, research and development of new technologies for the elimination or reductionofmicrofibersduringwashingandpurificationthatarecompatiblewithconventional systems.https://www.dam-aguas.es

This project has received public funds from the Strategic Programme of Consortia of National Business Research (CIEN)

NEW TAILOR-MADE SIZING STRATEGIES FOR RECYCLED CARBON FIBRES TO IMPROVE THE MECHANICAL PROPERTIES OF POLYMERIC AND CEMENTITIOUS COMPOSITESTheCUSTOMISIZEprojectaimstodevelopanewfamilyofcarbonfibres’sizinginordertoimprovetheinterfa-cialadhesionbetweenrecycledcarbonfibre(rCF)and polymers (thermoset and thermoplastics) and cementi-tious matrices. The goal of this is to improve the strength, toughness and environmental stability of the compo-sites prepared with the resized fibre. The specific sizing will bedeveloped fornonwovenmatandchopped towof recycledcarbonfibres.Thenew upgraded recycled carbon fibre will be used to produce new compositeswith cementitious or polymeric matrices (thermoset and thermoplastic).https://www.customisize.eu/

This project has received funding from the Clean Sky 2 Joint Undertaking under the European Union’s Horizon 2020 research and innovation programme under grant agreement no 831858

BICISENDAS

A NEW BIKE PATH INCREASING COMFORT, SAFETY, COMMUNICATIONS AND ENVIRONMENTALLY FRIENDLY The BICISENDAS project will develop a new bike path that will integrate several technologies to help increase comfort, safety, communications, and improve the environment around it; therefore, contributing to promote sustainable transportation. This project introduces the concept of modules for bike paths, that allow the selec-tion of different integrable technologies to personalize paths according to each city´s needs. Sustainable mate-rials for the module structure will be developed, using industrial waste and sub-products. Two types of modules will be designed: permeable and non-permeable, and each type will be compatible with different technologies.https://projects.leitat.org/bicisendas

Este proyecto ha recibido financiación pública del Programa Estratégico de Consorcios de Investigación Empresarial Nacional (CIEN) del Centro para el Desarrollo Tecnológico Industrial (CDTI).

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COMMUNITY FOR ADDITIVE MANUFACTURING AND 3D PRINTINGWithin the projects of the LLAVOR 3D Community, new software tools, newmaterials,moreefficientandver-satileproductionprocesses,newpost processes and surface treatments as well as new 3D printing applications will be developed, contributing to the creation of an R&D ecosystem in additive manufacturing technologies reinforcing the position of Catalonia as an international benchmark.https://projects.leitat.org/llavor3d

Aquest projecte està cofinançat pel Fons Europeus de Desenvolupament Regional de la Unió Europea en el marc del Programa Operatiu FEDER de Catalunya 2014-2020

COMMUNITY RIS3CAT FOR WATER TREATMENTThe RIS3CAT COMUNITAT AIGUA is a community of 56 entities between companies, technology and research centers, universities and associations, with the aim of promoting the economic transformation of the compa-nies linked to the management and consumption of water through the acquisition of knowledge and develop-ment of technologies to overcome existing technological challenges and respond to environmental, social and economic needs as well as the demands of future policies.https://projects.leitat.org/comunitat-aigua

Aquest projecte està cofinançat pel Fons Europeus de Desenvolupament Regional de la Unió Europea en el marc del Programa Operatiu FEDER de Catalunya 2014-2020

LITHIUM SULPHUR FOR SAFE ROAD ELECTRIFICATIONLISA proposes the development of high energy and safe LiS battery cells with hybrid solid state non-flammable electrolytes validatedat 20Ah cell level according to EUCAR industrial standards for automotiveintegration.LISAwillsolvespecificLiSbottlenecksonmetallic lithium protection, power rate, and volumetric energy densi-ty; together with cost the main selection criteria for EV batteries.www.lisaproject.eu

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 814471

HYBRID AIRCRAFT SEATING MANUFACTURING AND TESTINGtion aircraft seating obtained in the HAIRD project. Within the HAIRD project a new seating with reduction of Deep Vein Thrombosis (DVT) risk, multi-functionality and simple surfaces for composite manufacturing was designed. The molds to manufacture the structural parts and the cushion will be manufactured. These molds will be designed in detail taking into account the composite manufacturing techniques of Sheet Moulding Com-pound (SMC), Wet Compression Molding (WCM) and Prepreg Compression Moulding (PCM) comolded with SMC. www.hairmate-project.eu

This project has received funding from the Clean Sky 2 Joint Undertaking under the European Union’s Horizon 2020 research and innovation pro-gramme under grant agreement No. 821300

MANUFACTURING OF THE LINING PANEL USING HYBRID TECHNOLOGIES; ADDITIVE MANUFACTURING, INJECTION MOULDING AND THERMOFORMINGMAYA project main objective is to develop innovative manufacturing routes integrating standard thermoplastic processes (injection moulding and thermoforming) and additive manufacturing to realize lining panels of fuse-lage to reduce weight, optimize costs and enhance the part performances.https://projects.leitat.org/maya

This project has received funding from the Clean Sky 2 Joint Undertaking under the European Union’s Horizon 2020 research and innovation pro-gramme under grant agreement No. 831989

EMPOWERING CONSUMERS TO PREVENT DIET-RELATED DISEASES THROUGH OMICS SCIENCESPREVENTOMICS builds a new paradigm in preventive personalised nutrition based on the potential of omics, especially metabolomics, accessible for everyone. The main outcome from PREVENTOMICS is a novel Food Platform, a unique-in-its-kind service, interoperable with current existing Apps for monitoring health status and with personalized nutrition software, thus opening the door to the personalization of any type of health treat-ment where combinations of genetic, biological, nutritional and psychological factors are important.www.preventomics.euThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 818318

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TOWARDS A GREEN AND SUSTAINABLE ECOSYSTEM FOR THE EU PORT OF THE FUTUREPortForward proposes a holistic approach that will lead to a smarter, greener and more sustainable port eco-system which will include the following features: The introduction of an Internet of Things (IoT) concept for port assets (infrastructure, vehicles, cargo, people); The socio-economic analysis of the port interface with its surrounding area and the port-city, as well as the rest of the logistics value chain.www.portforward-project.eu


PAN-EUROPEAN ACCESS FOR SME ON TECH. SERVICES FOR CLEAN PRODUCTION THROUGH A NETWORK OF PREMIER KET TECHNOLOGY CENTRES KET4CP delivers standard procedures / tools for KET TC transnational collaboration and joint service/shared infrastructure, based on business model scenarios stimulating KET TC to collaborate and share clients. KET4CP creates a sustainable platform, a win-win situation for all stakeholders with a high potential for scale up. The aim for 2022 is to have 100 KET TC and 180 EEN members with 1000 SME inquiries p.a.www.ket4sme.eu


RECYCLING AND REPURPOSING OF PLASTIC WASTE FOR ADVANCED 3D PRINTING APPLICATIONSThe project aims to address all aspects and stages of thermoplastic and CF reinforced thermoplastic 3D printing material development from recycled resources, starting with the selection of suitable waste streams, strategies for material repair, compatibilization and upgrade towards AM processing, compatibility between different thermoplastic matrices and the reinforcing fibres and nanoparticles, comparative assessment of various AM thermoplastic processing technologies and closed-loop material optimisation in terms of processability and performance.http://www.repair3d.net


IMPLEMENTATION OF RISK GOVERNANCE: MEETING THE NEEDS OF NANOTECHNOLOGYGov4Nano will design and establish a well-positioned and broadly supported Nano Risk Governance Council (NRGC). Organizing, connecting and engaging are key activities in Gov4Nano and its creation of a sustainable NRGC. Gov4Nano will develop an operational trans disciplinary Nano Risk Governance Model (NRGM) for nano-technologies, building on an established governance framework developed by the International Risk Govern-ance Council (IRGC). Engaging stakeholders (including regulators) to proactively addressnano-specificsafetyandseekdialogueforjointactivities.www.gov4nano.eu


ARCHITECTURE AND TOOLS FOR THE QUERY OF ANTIBODY AND T-CELL RECEPTOR SEQUENCING DATA REPOSITORIES FOR ENABLING IMPROVED PERSONALIZED MEDICINE AND IMMUNOTHERAPYThe iReceptor Plus project will address several key challenges to optimally sharing AIRR-seq data among public and industrial partners: protecting patient privacy and the intellectual property of partners, performing complex analyses on data brought together from many sources, and expanding the size and number of repositories that can be integrated in the network.www.ireceptor-plus.com


INTELLIGENT FISH FEEDING THROUGH INTEGRATION OF ENABLING TECHNOLOGIES AND CIRCULAR PRINCIPLEiFishIENCi will deliver breakthrough innovations supporting sustainable aquaculture, based on enabling technol-ogies and circular principles, thereby providing the European aquaculture industry with the competitive ad-vantage and growth stimulation needed to be a moverinrevolutionizingglobalefficiencyinfishproductionandmeetsociety’sneedsforfoodfromtheocean.www.ifishienci.eu


BIO-MIMETIC AND PHYTO-TECHNOLOGIES DESIGNED FOR LOW-COST PURIFICATION AND RECYCLING OF WATERINDIA-H20 will develop, design and demonstrate high-recovery, low-cost water treatment systems for saline groundwater and industrial wastewaters. The focus for developments will be in the arid state of Gujarat, where surface water resources are very scarce. We will develop novel batch-reverse osmosis technology for a 10-fold reductioninspecificenergyconsumptionwithhighfractionsofwaterrecovery (80%) reducing /m3 operating costs to below €0.35/m3 (<30 rupees/m3).www.india-h2o.eu


CARE

PERSONAL PROTECTION EQUIPMENT FOR THE CONTROL OF ELECTRICAL RISKThe main objective of the CARE project is the development of a new individual protection equipment (EPI) based mainly on the detection of the electric field generated by high voltage cables, catenaries, transformers, etc. This new EPI will provide its users with a much higher level of protection against electrical hazards, give information on possible falls that the user may suffer and the state of health, allowing the necessary emergen-cy action without the need for user interaction.https://projects.leitat.org/care

Financiado por: FEDER/Ministerio de Ciencia, Innovación y Universidades – Agencia Estatal de Investigación/_Proyecto 2016-4764-7. Objetivo Temático del Programa Operativo: Promover el desarrollo tecnológico, la innovación y una investigación de calidad.

VALIDATION OF AN INDUSTRIAL PROCESS TO MANUFACTURE ISOSORBIDE BIS(METHYL CARBONATE) AT PILOT LEVELVIPRISCAR main objectives are to validate at pilot scale in an industrially relevant environment (TRL 5) a sus-tainable IBMC production process from IS and to show a proof of principle for the added value IBMC brings to the market by demonstrating the usefulness of polymers derived thereof in three high-volume market sectors: industrial coatings, hot-melt adhesives, and biomedicine (antithrombotic-antimicrobial catheters).www.vipriscar.eu


ROBOTICS OF EXTENDED RANGE FOR FLEXIBLE FACTORY

This project aims to eliminate the current industrial robotics limitations. Imagine an industrial robot that can move autonomously through the factory. The robot can go to the desired area to work, or move along a large object to perform operations. In addition, it can move within warehouse areas, picking up pieces and taking them to the points where they are needed. Rigid production infrastructures disappears. We can even think of making pilot plants to test complex processes.https://projects.leitat.org/trrex

Este proyecto ha recibido financiación pública del Programa Estratégico de Consorcios de Investigación Empresarial Nacional (CIEN) del Centro para el Desarrollo Tecnológico Industrial (CDTI).

PRECLINONCOPRECLINICAL REGULATORY DEVELOPMENT OF NEW ONCOLOGICAL DRUG CANDIDATESThe PRECLINONCO project pursues the main objective of obtaining the data about preclinical efficacy, toxicity, pharmacokinetics,pharmacodynamics and manufacturability needed to have a group of 1-3 candidates for new oncology drugs. The project will overcome the preclinical stage of the candidates selection and the initial phase of pre-regulatory toxicology program at least in one of the best threefinaliststosometumorindicatorsunderstudy(lung,pancreasand kidney cancer in adults, and pediatric rhabdomyosarcoma).https://projects.leitat.org/preclinonco

Financiado por: FEDER/Ministerio de Ciencia, Innovación y Universidades – Agencia Estatal de Investigación/_Proyecto RTC-2017-6037-1. Objetivo Temático del Programa Operativo: Promover el desarrollo tecnológico, la innovación y una investigación de calidad.

INMUNOSIGHT

IMMUNOLOGICAL AND MOLECULAR CHARACTERIZATION IN LIQUID BIOPSY OF LUNG CANCER PATIENTS FOR IMMUNOTHERAPYThe main objective of the project is the development of a tool that allows to characterize from an immunologi-cal and molecular point of view thepatientsofnon-smallcelllungcancerinordertofindamolecularsignaturethatallowsstratificationofpatientsagainstimmunotherapy,integratingclinical,molecularandimmunologicaldataspecifictothetumor and that identifies the long survivorswith these treatments,currently impossible to recognize in advance with any known parameter. https://projects.leitat.org/inmunosight

Financiado por: FEDER/Ministerio de Ciencia, Innovación y Universidades – Agencia Estatal de Investigación/_Proyecto RTC-2017-6502-1. Objetivo Temático del Programa Operativo: Promover el desarrollo tecnológico, la innovación y una investigación de calidad.

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Leitat is a Notified Body nº0162, authorized by the Ministry of Industry, Energy and Tourism to perform the Conformity Assessment (CE marking) of Protective Equipment according to the Directive 89/686/EEC, the evaluation of the quality control of the finished product (Article 11A) and according to the REGULATION (EU) 2016/425 of the European Parliament and the Council. Compliance with the type based on internal control of production and on the supervised control of the product at random intervals (C2 module) for category III protective equipment that provides for protection against serious risks or danger of death. Applicable even to Construction products according to European Regulation 305/2011 for system 3.

• Recognized laboratory by the International Automobile Federation (IAF) to perform testing on protective clothing and gloves for pilots according to standard FIA 8856-2000.

• Recognized laboratory by CIK-FUI for the homologation of karting suits.

LEITAT NOTIFIED BODY

+ Photo_Burning_Behaviour_Source_Archives_Leitat

ADVANCED TECHNOLOGY SOLUTIONSSCIENTIFIC AND TECHNICAL SERVICESTECHNICAL CAPACITY AND CHARACTERIZATION OF MATERIALSBecause of its vocation to multisector service, Leitat constantly updates to provide latest technology in order to perform characterization and behaviour of materials, targeted at a wide range of sectors

Behaviour of materials

• Mechanical properties (traction, bending, compression, peeling, coefficientsoffriction,adhesives,perforationandothers) • Abrasion, wear and scratching tests • Impact resistence • Hardness (Shore A & D, ball penetration) • Reometry(MFI / MVR) / Viscosity • Density of liquids and solids • Water permeability, vapour resistance, liquid absorption, and others • Electrostatic charges • Colour solidity, wash resistance and comfort • Tribological tests • Ageing of materials: • Ageing due to radiation: Xenotest, QUV, IR • Solar simulation: MHG lamps • Climate ageing: climatic chambers, stoves • Natural ageing • Microscopy and colorimetry • Optical microscopy (MO) and electronics (SEM) • Macro and microphotography • Cross sections, coatings • Studies of defects and degradation • Appearance

Analytical Chemistry • Identificationandcharacterisationofpolymersandadditives • Determination of the molecular weight in polymers (GPC) • Total and mitigation analysyis of metals in polymers • Carbon emission (automotive industry) • Formaldehyde emission (automotive industry) • TTT • Fogging of condensable components (automotive industry) • GlobalandspecificMigrationstudies • Nanoparticles analysis • Elemental analysis (N,C, O, H y S) • Traces of water analysis (Karl Fisher) • Analysis of encapsulated products

EU-EcolabelTests and evaluation of environmental criteria for all categories.

• Textile products • Surface cleaning products• Detergents for clothes• Detergents for industrial and institutional clothes • Detergents for dishwashers• Detergents for industrial and institutional dishwashing• Hand dishwashing detergents• Cosmetics (requiring rinse)• Paints and varnishes• Furniture• Lubricants• Paper• Tourist accommodation• Campsites

Environment• Analysis of waste water (DQO, DBO5, NTK, SSD, SSV, etc.)• Analysis of anions and fatty volatile acids • Analysis of metal son soil and water • Analysis of emerging pollutants • Test son biodegradability • Analysis of biogas • Analysis of pollutants in air • Analysis of fertilizers( NPK)

Food

• Analysis of fatty acids (GC-FID) • Analysis of proteins • Analysis of total polyphenols and antioxidant power • Analysis of total protein • Analysisoffibre • Analysis of sugar • Analysis of metals (Hg, As, Cr, etc.)

Protection – Gloves and Clothes:

• Comfort tests for materials intended for protective clothing • Shear strength tests • Impact resistance tests and impact abrasion tests • Tests for materials for high-visibility warning signage • Tests for protective equipment against mechanical, thermal, chemical and microorganism risks • Testsformotorcyclistgloves,welders,firemenandothers • Testsforclothingwornbywelders,firemen,forestoperatorsand others

Validation of prototypes:

• Materials • Finished products • Industrial processes

Application of new technologies

• Plasma • Extrusion of polymers• RapidPrototyping–3DPrinting • Three dimensional metrology (in the lab) • Metrology of pieces; reports on homologation of casts and matrices • Measurement and graphical reports with CAD comparative method • Dimensional study for the analysis of assembly problems • Measurement of samples, statistical studies of process control • Automatic measuring programs for measuring machines by coordinates • Digitization and reverse engineering

Fire behaviour

• Tests for materials aimed at textile architecture • Tests for materials aimed at textile architecture • Testsforprotectiveequipmentagainstheatandflame • Accredited tests for IMO • RecognitionbyIberiaforthecertificationofproductsforsecurityagainstfire(aviation) • Testsforhydraulicfluids(Wicktest,Manifold)

Bioanalysis and health

• Antibacterial and antifungal activity of actives, materials and formulations • Modelsofformationandeliminationofbiofilms • Studies on microtoxicity and water microbiological control • Tests on enzyme activity • Studiesoncosmeticssecurityandefficacy(BPL) • Efficacytestofpreservativesincosmetics(ChallengeTest) • Studies on security for detergency products • Studies on security for medical devices • Studies on biodisponibility and alimentary allergenicity • Studies on absorption, distribution, metabolism, excretion and toxicity of medicaments (ADMEtox) • Bioequivalences (BPL) • Metabolomic analysis in vitro/ in vivo (GLP) • Studiesontheefficiencyofantitumorcompounds(invitroandinvivo) • Studiesontheefficiencyofpotentialdrugsagainstautoimmunediseasescausinginflammation(invitroandinvivo) • Generation of poli and monoclonal antibodies to be used in research, diagnosis, prognosis and therapy. • Design and development of biosensors diagnoses • Antibodies engineering: humanization and chimerization nanobodies, scFv,bi-specific,ADCs,fusionproteins,Biosimilars • Drugreprofiling

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LEITATUNDERTAKES EntrepreneurshipCreation, development and technology transfer with social implication in thenewmarketsby identifiedneedsof themarkets or sectors.Financial and competitive support in the development of the project/product to guarantee its impact in the market and capitalizing technology development.

Tech Mentoring Technology transfer from knowledge generating cores. Complete use of technology and knowledge obtained from research. Creation of actives and abilities to customers (technology, brand and systems).

Advanced Management Global-market oriented strategic administration.Directive competences and abilities. Flexibility and adaptability.

Growing Business Area Access to multisectorial equipment, using synergies with the Centre and in an Open Innovation environment to broaden the initiatives reach. Acceleration platform for internationalization. Complimentarity with other already existing projects.

FFF CommunityRelationshipwithfinancialfundsandpartnerstofacilitateandimprovethecompanyplansandthefirststagesoftheTechnology-Based Companies (TBC) projects.Generation of critical mass for business development by promoting and developing projects focused on growth and business consolidation oriented to market success.

LEITAT INNOVATION ConceptLab Definitionofconceptsforproducts,services, processes and business models that are authentically and aimed at the market.

Reorientation Search of new activities allowing an approach to new management models Information on technology Improve the technology level of products, services and processes. Usemechanismstobeabletofind, evaluate and transfer external technological knowledge. Training and Transfer Development of generic training actions thatarespecifiedontechnological topics and innovation management. Innovation management Implementation of a personalized model to improve innovative capacity

Processes improvement systems Improvement of processes by using moreefficienttechniquesandmanagement

DESCRIPTIONOF BUSINESSIDEA

VIABILITY

TEAM SELECTION

OBJETIVES

SCIENTIFICSUPPORT

ECONOMICANALYSIS

IDEA DEVELOPMENT

SPINOFF

STRA

TEGIC PLAN

ANALYSISOF MARKETNEEDS

SUMMARY OF ACTIVITIES 2018+ Creativity

+ Innovation

+ Learning

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LEITAT PARTICIPATES AT THE ANNUAL MEETING OF CLUB EXCELENCIAIn March 2018, SIEMENS headquarters in Madrid hosted the annual meeting of Club Excelencia,wheretheClub’stopExecutivesget together to dialogue on a model of excellencebasedonefficiencyandstrategicinnovation. Some of the topics discussed were the resources management and processesto improveefficiencyandtosaveenergy.

The objective of the meeting is to create an environment where the Executives of the Club's leading members share impressions and opinions about business in a relaxed atmosphere, in order to keep promoting the Club's motto: "Sharing and improving together".

LEITAT COLLABORATES IN THE PROMOTION OF YOUNG TALENTSIn February, the HP Barcelona International Centre hosted the graduation ceremony for the 68 students in the sixth year of Innotalent, a dual training programme promoted by HP in collaboration with La Salle Campus Barcelona-URL and Leitat.

The aim of the programme is to boost the talent of young graduatesinhigherengineeringandscientificcareersthrough innovation and dual training, establishing links between universities and companies and creating high value-added positions. Leitat collaborates in the promotion and selection of recent graduates, carrying out an individualized follow-up throughout the program. In the six editions of the program 250 engineers have participated, of which 143 have been hired after graduation to join the R&D team and Operations Center HP in Barcelona.

STUDENTS VISIT LEITAT’S FACILITIES IN CENTRE D’INNOVACIÓ ANOIA High school and training cycle students visited last March Leitat's laboratoriesatCentred'InnovacióAnoia tofindout how important it can be for companies to have a technology partner.

The visit is part of the technolog-ical route organized by Promoció Econòmica de l'Ajuntament de Vilanova del Camí, together with Leitat and the company Abacus, in which 132 students from various institutes in the region participated.

LEITAT AND EL CONSORCI DE LA ZONA FRANCA PROMOTE THE FIRST 3D PRINTING INCUBATOR IN SOUTHERN EUROPE

Last April, the project of the first 3D printing incubator insouthern Europe was presented: the 3D Factory Incu-bator. Promoted by El Consorci de la Zona Franca de Barcelona and Leitat,itwillbefinancedwithERDFfundsfromtheEuropeanUnion and will be inaugurated at the beginning of 2019.

The incubator, which will be located in Zona Franca and will have facilities of 600m2, will have a double objec-tive: to facilitate access to this new technology for small and medium companies in order to increase their competitiveness and, secondly, to act as a research centre on new tools in collaboration with the most power-ful corporations in the sector and emerging companies.

The equipment is designed to initially house 20-30 companies, although it is expected to have an impact on more than 800 corporations.

INAUGURATION OF THE IAM 3D HUB, A EUROPEAN CENTRE FOR DIGITAL INNOVATION IN 3DLocated in Leitat's facilities, the IAM 3D HUB was inaugurated in May. It is a centre specialized in additive manufacturing and 3D printing, with the intention of becoming a European benchmark in digital innovation. It is an initiative of Leitat, together with HP, Renishaw, Coniex-Abrast, and Fira Barcelona through the In(3D)ustry trade show.

The IAM 3D HUB aims to accelerate the adoption and development of 3D printing technologies and additive manufacturing in manufacturing sectors, involving both technology professionals and economic agents. The center will work with all types of companies and sectors, from start ups and SMEs to large companies that are interested in adopting this technology through experimenting and testing, end to end solutions and business and mentoring services.

LEITAT PARTICIPATES IN THE PRESENTATION OF THE KAUTIC 2018 PROGRAMIn April, the 5th edition of KauTic 40 was presented, an incubation programme for entrepreneurial projects in the field of information and communication technologies(ICTs), which fosters and drives business activity through a combination of specialised training, accompaniment with specialist tutors and co-working spaces.

The program, which has a duration of 9 months, started fiveyearsagointheframeworkofOrbital40,promotedbythe City of Terrassa and Leitat, with the collaboration of the business school Euncet. During this 5th edition, the 10 projectsbenefiting from theprogramme receivea totalof50 hours of training sessions and 300 hours of specialised consultancy in different areas of the company.

26 27

PRESENTED THE PROJECT TO ACCELERATE THE DIGITAL TRANSFORMATION OF COMPANIES: DFACTORY 4.0AttheendofOctober,Leitat'sfacilitiesinTerrassahostedtheofficialpresentationofDFactory,thehubde-signedtopromoteIndustry4.0and additive technology among companies. Promoted by Fundación Leitat to-gether with Consorci de la Zona Franca de Barcelona, the hub aims to be the technological dynamiser and ref-erence centre for those companies that want to advance in their digital transformation, and for this purpose it aims to attract not only technology but also talent, entrepreneurs and companies that are committed to this new era.

The DFactory will have 17,000m2 and will begin at the beginning of 2019 with the construction of 600m2 that will house the 3D Factory Incubator,thefirstincubatorinsouthernEuropespecializinginadditivemanufactur-ing.

LEITAT LEADS THE CONSORTIUM THAT WILL DESIGN THE AIRCRAFT SEATS OF THE FUTUREHairmate is a research and development project carried out by an international consortium, led by Leitat and supervised by the Fraunhofer Institute, which has received a grant from the European Union's (EU) Horizon 2020 programme to manufacture and test the next generation of aircraft seats: lightweight, recyclable, cost-effective and with the capacity to reduce deep vein thrombosis. The initial meeting of the project was held on 28 November at the headquarters of Leitat Terrassa.

The project is part of the European Clean Sky 2 initiative, which aims to improve the environmental impact of European aeronautical technologies and ensure the future international competitiveness of the European aeronautical sector.

MEETING BETWEEN THE GOVERNOR OF THE PROVINCE OF LIMA AND LEITAT CHILEOn June 12, in the offices of the Governorate of Limarí,representatives of Leitat Chile met with the Governor of the Province of Limarí to present the draft of the project "Technology Center for small regional mining".

The objective is to create a center that is implemented in stages and is part of the development of the region. It will try to meet the needs of companies in the region and plan models of growth and governance of the same, from a specialized laboratory and with a competent technical direction.

CIMTI BEGINS ITS JOURNEY WITH A URINARY CATHETER MODEL THAT WILL REDUCE INFECTIONS

CIMTI, an organisation promoted by Fundación Leitat with the support of Generalitat de Catalunya, began its implementation in Aprilwiththeselectionofthefirstfourprojectstobecarriedout,allfrom public hospitals, including a new model of urinary catheter that will improve patient comfort and reduce infections.

Other future projects include: the development of a more effective, non-invasive method for diagnosing colorectal cancer; a new patient monitoring system in the intensive care unit (ICU) that integrates all the data from several medical devices into a single monitor; and an assistive device aimed at people with blindness that incorporates several sensors into a device.

LEITAT COORDINATES LLAVOR 3D, THE NEW RIS3CAT COMMUNITY OF ADDITIVE MANUFACTURING AND 3D PRINTING Last May, the community LLAVOR 3D was founded, within the framework of the RIS3CAT strategy and coordinated by Leitat. It groups 31 Catalan entities and will execute 4 projects with a budget of almost 11M€. The objective is to accelerate the development and adoption ofadditivemanufacturingand3Dprintingbytheindustrialsectortoimproveitscompetitiveness.Itisco-financedbytheGeneralitatdeCatalunya through ACCIÓ, through a grant of up to 3.8 million euros from the FEDER fund.

More than 100 people participated in the event, from the 31 member entities of the Community as well as from other collaborating entities that will be actively linked. Both SMEs and large companies, research centres and universities from the Catalan innovation system participate in the Community.

LEITAT AND AJUNTAMENT DE VILANOVA DEL CAMÍ ORGANIZE THE 4th INNOVATION DAY IN THE REGION OF ANOIAThe circular economy and the new resource management model were the focus of the IV Jornada d'Innovació a l'Anoia held in June at Centre d'Innovació Anoia.

The event, organised by Promoció Econòmica de l'Ajuntament de Vilanova del Camí and Leitat, was attended by some 80 companies, industrialists and other social and economic agents interested in the circular economy.

28 29

GOVERNMENT DELEGATE VISITS LEITATTeresa Cunillera, Government Delegate in Catalonia, visited Leitat’sfacilitiesinOctobertolearnabouttheac-tivitiesthattake place in the center.

In the meeting with the Board of Directors, Leitat's strategic lines were presented and topics such as the state of innovation in Catalonia and the current agents of the system, and innovation at an international level were discussed. Collaboration links were also established with short, medi-um and long term proposals.

LEITAT LEADS THE PROJECT OF THE DEVICE THAT WILL ALLOW DETECTING METASTATIC BREAST CANCER IN REAL TIMEThe HypoSens project, led by Leitat, will develop a device for the diagnosis of metastasis in breast cancer much more effective and less invasive. It will be based on the administration ofbio-compatiblenano-capsulesthatarespecificallyanchoredtometastatictumourcellsthanks to their surface antibodies and, by means of a dual system of internal sensors, temperature and oxygen can be determined by means of an external imaging de-vice. These metabolic parameters analyzed correlate with the aggressiveness of the cancer and facilitatethecorrectstratificationofpatients.Thus,thediagnosiswillbefast,lowcost,safe,with high resolution and sensi-tivity, and much less invasive than surgery.

LEITAT RENEWS ITS ACCREDITATION AS AN AMED ESTABLISHMENTLeitat’scafeteria,managedbythecateringcompanyCOCO,hasrenewedtheAMEDcertificationonemoreyear.

Awarded by the Public Health Agency of Catalonia of the Generalitat de Catalunya, this accreditation certifies thatLeitat promotes Mediterranean food in its cafeteria, meeting the mandatory criteria and requirements of food and non-food nature of the AMED Program.

COMPANIES FROM THE METALLURGICAL SECTOR VISIT LEITAT

Several companies of the metallurgical sector of the region of Anoia participated last July 19 in a technical visit to the facilities of Leitat Terrassa, a visit organized by the Business Union of Anoia because of the business in-terest manifested by research and technological development of the sector itself.

During the visit, the techni-cians and managers of the different attending companies could know the origin, the trajectory and the tasks that LEITAT carries out, and visited the facilities and laboratories.

2018 ACTIVITYREPORT

29862309872319640121283567832 291623098723196401212835601393878322297701018327229770101832298623098 723196401212835678322297701018723196 4012128 35678322297 701018 3272291270101832298 62 309 872319640121283567832229770101836327231964012 1283 56 78322297701018327229770101832429862309872319864012128 356 783222977010183

30 31

2018 ACTIVITY REPORTPEOPLE:Leitat's efforts are aimed to increase the number of the Collaborators currently included in a team of experts in different areas of knowledge. Moreover, it focuses its attention on a talent management policy offering technological feedback with a high added value.

Number of collaborators College Graduates Distribution (31st Dec 2018) Average age: 36 years

OUTPUTS We are participating in European projects with a total of 588 partners, overall budget of 375M € and collaborating with 45 countries 75 R&D+2i ongoing European projects 156 R&D+2i ongoing National projects 29 Projects led 406 Industrial projects 4.565 Advanced Technology Solutions

LAST THREE YEARS

312

51%Women

(158)

49%Men(154)

26%Doctors

(82)

14%Others

(42)

60%College

Graduates (188)

2100+customers

750+projects

500+M€ impact

300+staff

75+countries

50+M€ income

30

2018 ACTIVITY REPORT INCOMES:In recent years, the evolution of Leitat has been focused on creating sustainable and lasting value technology, aligned with the needs and expectations of the market, with an economic return for companies and institutions.

Income in thousand Euros Distribution of total revenues by activity

EBITDA : 1,9M€

BALANCE: Thousand Euros

Fixed assets: 13.646 Debtors: 20.283 Financial assets: 9.670 Total: 43.599

Shareholders’equity: 15.449 Non-current assets: 10.907 Current assets: 17.243 Total: 43.599

24,4

€

31

17,5%Projects with Non competitive public funding

22,5%Own R+D+i Projects

60% R+D+i projects for companies

32

OUR COMMITMENTWe keep on strengthen

our commitment with the Corporate Social

Responsibility through initiatives aimed at providing social and technology value

to our stakeholders:

Customers, affiliates, suppliers, public

administrations, related businesses, partnerships and

enterprises.

With society • Decisive commitment for dual training as basic tool of the business fabric and the educative community

forthecreationofnewprofessionalprofileslinkedtotheindustrialsectorandR+D.Leitatdoesnotonly actively and jointly participate in the creation of these new professional and with entities aimed at this purpose.

• Cooperation in mentoring programs for young people for their admission to work, through the collaboration with organizations such as Barcelona Activa.

• Cooperationwithnon-profitfoundationsforthepromotionofcorporatevolunteeringcampaignsandactions, as well as for the promotion and commitment to cultural, age and gender diversity.

• Cooperation in programs for young entrepreneurs such as technical coordinators and as project evaluators in several Institutional and technical juries.

• Promotionanddiffusionofscientificcareersamongstudents, futureworkersof theknowledgeandinnovationsocietythroughthecooperationwithpublicandprivateorganizationsinspecificprojects.

• Creation of special days and invitation of trainees in different areas of Research and Technological Solutions of Leitat both nationally and with international organizations as well as welcome of students with Leonardo scholarships, Erasmus projects, etc.

• Cooperation with local agents (Consorci per l'Ocupació del Vallès Occidental) with regards to strategic policies linked to entrepreneurship and environmental sustainability and to the attraction of business activities generating a direct impact on the creation of industrial jobs.

• Participation in the 'Setmana de la Ciència' (European Science and Technology Week) by using our facilities for visits focused on the topics and technological lines of the future.

• Professional and Business Orientation Seminars for Institutes, Private Schools and Universities to attract talents.

• Cooperation in commissions linked to the promotion of talent development and diversity.

• Cooperation with foundations and organizations for the promotion of training and admission to work.

• Participation in working groups with the different public representatives of politics, in the creation of possible proposals arising from executive actions and legal measures providing for a positive impact in the reactivation and economic growth mainly based on Research, Development and Innovation (R+D + i) and, in concrete, in the real transfer of knowledge to SMEs.

With our employees • Investment in training plans according to the needs of our employees, their performance and career,

applying an annual estimate depending on the needs of each organization department of Leitat.• Subsidy and promotion of doctoral degrees• Offering our employees the chance to give and receive inner/external training.• Promotion and development of our employees in the following and management of students in

internship.• Welcome actions to facilitate the adaptation of internship students of different cultures for their

integration in Leitat and in the cities of Terrassa and Barcelona. • Reinforcement of the corporative culture through different channels to facilitate inner communication.• Realization of after-work activities to encourage a satisfactory and conciliatory atmosphere among

the staff.• Specificcampaignsonthepromotionofhealthyhabitsinthedailylife,environment,riskprevention

and security for all.• Existence of the Agent for Equality in the welcome programs and training actions aimed at our

personnel.• Reconciliationmeasuresandflexibilityforourstaff• Leitat joins the European Week of Waste Prevention with activities including the Workshop and study

on food waste, the prevention of packaging waste, the product reuse, the distribution of the cup 'Llença't a no llençar'

• Leitat participates in the Week of Sustainable and Safe Mobility with activities such as the car sharing which facilitates the combination with public transport and promotes the efficient driving manual.

Environmental informationWithin the framework of its environmental strategy and in compliance with the new circular economy models, LEITAT monitors its processes for the optimization of its environmental performance through an Integrated Management System (EMAS, ISO 14001, ISO 9001 and ISO166002). This corporate report has been published according to environmental criteria to optimize the use of resources, reduce the generation of waste and therefore reduce its carbon footprint.

ThepaperisFSC®certified.Itimpliesthemonitoringofpaperproductionwithresponsible environmental, economic and social management of forests.


LEITATAcondicionamiento TarrasenseTel. (+34) 93 788 23 00 Fax. (+34) 93 789 19 06

www.leitat.org [email protected]

TERRASSAC/de la Innovació, 208225 Terrassa (Barcelona)

BARCELONADistricte 22@C/Pallars, 179-185 08005 Barcelona BARCELONAParc Científic de BarcelonaC/Baldiri Reixac, 15-21 08028 Barcelona

VILANOVA DEL CAMÍCentre d’Innovació AnoiaC. dels Impressors, 12 08788 Vilanova del Camí (Barcelona)

VHIR – Vall d’Hebron Institut de Recerca EdificioMediterránea.HospitalValld’HebrónPasseig de la Vall d’Hebrón, 119-12908035 Barcelona

Biopolo La FeHospital La Fe, Torre A, Planta BajaAvenida Fernando Abril Martorell, 10646026 Valencia

+Photo_Home_INDICATOR_Chemical_efficiency_degradation_Ozone_File_Leitat

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