Mahasen Ali Radwan, Ph.D. Professor of Clinical Pharmacy

Department of Pharmaceutics and Pharmaceutical Technology

College of Pharmacy

Egyptian Russian University

Suez road, Bader City, Cairo, 11829, Egypt

Tel: +20-2-22636589 / Mobile: +20-1005211461

NATIONALITY: Egyptian

SEX: Female

MARITAL STATUS: Married

EMAIL: dr_mradwan@yahoo.com ma-radwan@eru.edu.eg

DATE: January 2019

EDUCATION

March 1988 Ph.D. - College of Pharmacy, University of Georgia, GA, U.S.A.

Dissertation - "Microencapsulation of Disopyramide for Oral Sustained

Release and Subsequent Pharmacokinetic Studies in the Dog"

Major Professors - Drs. James C. Price and Randall L. Tackett.

August 1985 M.Sc. - College of Pharmacy, University of Georgia, GA, U.S.A.

Thesis - "Development of an HPLC Assay for Quantitation of

Oxamniquine in Biological Samples and its Application to

Pharmacokinetic and Tissue Distribution Studies in Animals"

Major Professor- H Won Jun.

May 1978 B.Sc. with honor, College of Pharmacy, Cairo University, Cairo, Egypt.

WORK EXPERIENCE

December 2017 – Present

Head of the department of Pharmaceutics and Pharmaceutical Technology,

Head of the fifth year's Control, College of Pharmacy, Egyptian Russian

University (ERU), Bader City, Cairo, Egypt

September 2016 – Present

Professor-College of Pharmacy, Department of Pharmaceutics and

Pharmaceutical Technology, ERU, Bader City, Cairo, Egypt

Teaching responsibilities at ERU: Teaching undergraduate courses: Pharmacy

Practice I, Pharmacy Practice II, Clinical Pharmacy I, Clinical Pharmacy II,

Hospital Pharmacy and Biopharmaceutics and Pharmacokinetics.

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September 2011 – August 2016

Professor-College of Pharmacy, Department of Pharmaceutical Practice,

Princess Nourah bint Abdulrahahman University (PNU) Riyadh, Saudi Arabia.

Teaching responsibilities at PNU: Teaching and sharing teaching undergraduate

courses, CPP312 (Biopharmaceutics and Pharmacokinetics) to level 5 or 6,

CPP411 (Drug information and Literature Evaluation) to level 7 and CPP416

(Principles of Evidence Based Practice) to level 8.

2013- 2016: Scientific Coordinator-Foundation Year – PNU Health

Colleges. 2011-2013: Supervisor of the Academic Advisory and Student

Support Unit.

2011-2016: Internal Supervisor for Bushra AlQuadeib, Ph.D. through the

External supervision program of King Saud University with Newcastle

University,

Newcastle, United Kingdom. Thesis title: “Pharmaceutical Studies of

Amphotericin – B: Oral Formulation using Nanotechnology”

2013-2018: Internal Supervisor for Alanoud Almurshidy through the

External supervision program of King Saud University with Liverpool

University, Liverpool, United Kingdom. Thesis title: “Development of Afatinib

lipid nanoparticles targeting Non-Small Cell Lung Cancer”

June 2002 – August 2011

Professor-College of Pharmacy, Department of Clinical Pharmacy, King Saud

University (KSU) Riyadh, Saudi Arabia.

December 1995 – June 2002

Associate Professor-College of Pharmacy, Department of Clinical Pharmacy,

King Saud University, Riyadh, Saudi Arabia.

September 1992 – December 1995

Assistant Professor-College of Pharmacy, Department of Clinical Pharmacy,

King Saud University, Riyadh, Saudi Arabia.

Teaching responsibilities at KSU- Sharing teaching of undergraduate and

graduate courses, Departments of Clinical Pharmacy (PHCL) and

Pharmaceutics (PHT) as: PHCL481 (Evidence Based Medicine), PHCL 311

(Pharmacy Practice), PHCL461 (Basic Pharmacokinetics), PHCL462 (Clinical

Pharmacokinetics), PHCL510 (Graduate-Advanced Clinical Pharmacokinetics),

PHT531(Graduate-Advanced Biopharmaceutics), PHT533(Graduate-Controlled

Drug Delivery Systems), PHT 521 (Graduate Hospital Pharmacy),

PHT451(Dispensing of Medication I), PHCL476 (Computer in Pharmacy),

PHCL471(Hospital Pharmacy) and PHT351 (Sterile Products).

Supervisor for M.Sc. Students: Ola Alomran, Maha Alderimli, Nouf Alouda,

Rania Algezani, Safaa Almyibid, Esraa Altaweel, Leena Said; in their research

projects (Department of Clinical Pharmacy).

Co Supervisor for M.Sc. Students: Zahra Alrays, Department of Zoology,

Yossra Alzeen, Department of Biochemistry, College of Science.

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Co Supervisor for Ph.D. Students Rash Kamel Department of Biotechnical

Engineer (Syria).

External Examiner: M.Sc Students (Department of Pharmaceutics and

Zoology).

April 1989 - August 1992

Assistant Professor - Albany College of Pharmacy, Department of

Pharmaceutics, Albany, NY, U.S.A.

Responsibilities: Shared teaching duties in required and elective pharmacy

courses in pharmaceutics, Course Coordinator of Biopharmaceutics and

Pharmacokinetics, and taught Clinical Pharmacokinetics course to

Pharm.D students. Conducted research in the area of Pharmacokinetics,

Pharmaceutical Drug Delivery Systems and Drug Analysis.

Supervised Pharm.D. and undergraduate students in different research

projects.

March 1988 - March 1989

Research Associate, Pharmaceutical Research and Development,

Hoffmann-La Roche, Nutley, NJ, U.S.A.

Responsibilities included the development of In Vitro release techniques to study

the effect of excipients on drug release to screen different formulations,

correlation between in vitro and in vivo results, development of parenteral

sustained release formulations and studying the effect of formulations on drug

disposition and bioavailability in rats.

April 1985 - February 1988

Teaching Assistant - Department of Pharmaceutics, College of Pharmacy,

University of Georgia, U.S.A.

Responsible for assisting junior students in dispensing laboratories

August 1983 - June 1984

November 1978 - June 1984

Inspector - Ministry of Health, Cairo, Egypt

Responsible for inspecting the activities of the scientific offices according to

Ministry of Health regulations and the registration of new drugs in Egypt

according to Ministry of Health and FDA guidelines.

DISTIGUISHED RESEARCH AND PUBLICATION QUALITY AWARDS:

From PNU (2016):

1. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Ben Horrock, Matthew Wright

“Stealth Amphotericin B Nanoparticles For Oral Drug Delivery: In Vitro Optimization” Saudi

Pharmaceutical Journal, 23 (3):290-302 (2015) ISI*

2. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-

Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery System”

Drug Delivery , 22(3): 320–327 (2015) ISI*

3. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Elaine Mutch, Ben Horrock,

4

Matthew Wright and Abdulaziz Alshaer “Therapeutic Monitoring of Amphotericin B in Saudi

ICU Patients using UPLC MS/MS Assay” Biomedical Chromatography, 28 (12): 1652–1659,

(2014) ISI*

4. Mahasen A. Radwan, Nayira A. Abdel Baky, Iman Y. Zaghloul , Hassan Y. Aboul‐Enein,

“Pharmacokinetics and Cardiovascular Effect of Etoricoxib in the Absence or Presence of

St. John's Wort in Rats” ArzneimittelForschun-Drug Research, 62: 313–318 (2012). ISI*

From KSU (2011 & 2015):

1. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-

Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery System”

Drug Delivery , 22(3): 320–327 (2015). ISI*

2. Mahasen A. Radwan, , Bushra T. Alquadeib, Nouf M. Aloudah, Hassan Y. Aboul

Enein“Pharmacokinetics of Ketorolac Loaded to Polyethylcyanoacrylate Nanoparticles

Using UPLC MS/MS for its Determination in Rats” International Journal of Pharmaceutics

Volume 397(1-2):173-178(2010) ISI

3. Zaghloul IY, Radwan MA, Al Jaser MH, Al Issa R “Clinical Efficacy and

Pharmacokinetics of Antimony in Cutaneous Leishmaniasis Patients Treated With Sodium

Stibogluconate” : Journal of Clinical Pharmacology, 50(11):1230-1237 (2010).

4. Mahasen A. Radwan, Iman Y. Zaghloul, Nayira A. Abdel Baky “Stability indicating high

performance liquid chromatographic assay for the pharmacokinetics of Cyclooxygenase

(COX-2) inhibitor etoricoxib in rats” African J. of Pharmacy & Pharmacology, 3(7):339346

(2009). ISI

RESEARCH INTERESTS

Development and Pharmacokinetics of drug delivery systems especially

Nanoparticles and drug targeting, Clinical Pharmacokinetics (Therapeutic Drug

Monitoring and Drug interaction) and Pharmacogenomics. Drug Analysis in

biological fluids using HPLC, UPLC MS/MS, and Chiral analysis. The effect of

Diatery Supplements, especially antioxidents, on the pharmacokinetics of drugs.

Computer data handling and modeling using in-house or commercial software.

VISITING SCIENTIST

July-September 2008 School of Pharmacy and Pharmaceutical Science, University of Central

Lancashire, Preston,UK. To conduct research in the area of liposomes and

niosomes (Nanoparticles) for amphotericin B oral and lung delivery with

Professor Anthony D'Emanuelle.

July-August 2004

Department of Pharmaceutical Technology, Free University of Berlin, Berlin,

Germany. To conduct research in the area of Solid Lipid Nanoparticles (SLN)

of amphotericin B and Cyclosporin with Professor Rainer Mueller.

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COMMITTEES AND SCIENTIFIC SERVICE (Some)

November 2016 – Present: The head of the “Community participation and environmental

development”committee.

November 2015 - July 2016: Consultant to AlFisal New College of Pharmacy to Build the

Course Specifications, Laboratory and Program According to the NCAAA

Requirement.

September 2015 - August 2016: A member of the College of Pharmacy Research Center.

August 2014 - June 2015: A member of the “Standing Committee of Scientific Publications

Subdivision of the Scientific Council, Princess Nourah bint Abdulrahman

University.

August 2011 - June 2015: A member of the Scientific Council, Princess Nourah bint Abdulrahman

University.

August 2011- June 2014: The head of “Standing Committee of Employment and Scientific

Awards” Subdivision of the Scientific Council, Princess Nourah bint

Abdulrahman University.

August 2013-June 2015: A member of the “Standing Committee for Research Excellence” for the

awards of the distingushed research and distingushed researchers at Princess

Nourah bint Abdulrahman University.

2013 –2016: The head of the “Scientific Research Committee and Community Service” for the

quality assurance and Academic Accreditation of Standard 10 and 11 (Scientific

Research and Community Service).

2013-June 2015: A member of the “Princess Nourah research Center: Woman health research” for

the Princess Nourah Research Center and Central Labs: “Woman health

research”.

2013: A member of the “Commission to Study the scientific research and community service” for

studying the status of scientific research and community service at Princess

Nourah bint Abdulrahman University (Subdivision of the study of the Strategic

Plan of Princess Nourah bint Abdulrahman University for the future).

2013-June 2015: The head of the “Scientific Research Committee” for establishment of central

research laboratory of the College of Pharmacy of Princess Nourah bint

Abdulrahman University.

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2009-2011:

A member of the “Scientific Research Committee” for the establishment of the

construction and the selection of the design and equipment of the new Prince Naif

Central Research laboratory at King Saud University, new campus for girls.

2009-2011:

A member of the “Scientific Research Committee” for the establishment of the

College of Pharmacy Central Research laboratory at King Saud University new

campus for girls.

2010:

A member of the team of the “SWAT analysis” as part of the strategic plan of

King Saud University.

1995-2008:

A member of the Advisory Board of Saudi Pharmaceutical Journal.

1991-1992: A member of the “Task Force committee” for moving the curriculum of Albany

College of Pharmacy towards “All PharmD.” program, Albany, U.S.A.

1992-Present: A reviewer for the Journal of Pharmaceutical Sciences, European Journal of

Pharmaceutical Sciences, Pharmacy and Pharmacology, American Journal of

Health-System Pharmacy and others.

2000-Present: Referee for King Abdel Aziz for Science and Technology, for research proposal,

progress and finals reports.

ORGANIZATIONS

1. 1986-Present: Member of the American Association of Pharmaceutical Scientists

(AAPS).

2. 1994-Present: Member of the Saudi Pharmaceutical Association (SPHA). 3.

1987-Present: Controlled Release Society (CRS)

SELECTED TRAINING COURCES/WORKSHOPS ATTENDED

April 5 & 12 ,2016 “Professional Development” program, 12 hours, Center for Excellence in

Teaching and Learning. Pricess Nourah bint Abdulrahman University.

Feb. 25, 2016

“Professional Portfolio” program, 4 hours, Center for Excellence in Teaching

and Learning. Pricess Nourah bint Abdulrahman University.

Dec 29,2014

“Applying Standards of Quality Assurance and Academic Accreditation” Dr.

Hannan Algadhi, Pricess Nourah bint Abdulrahman University.

Dec 7, 2011 “Quality Assurance and Academic Accreditation” Dr. H. AlOlyan, Pricess

Nourah bint Abdulrahman University.

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Nov 30-Dec 2, 2010 “Teaching how to teach” Partners Harvard Medical International (Faculty

development Program) Novotel Hotel, Riyadh

Sept 19-21, 2010

“Motivating student, active learning and assessing student learning

Worhshop” by Experts from USA given in Almalaz Campus (Faculty

development Program), Riyadh

Feb 2-4, 2009

“Parametric and Nonparametric SPSS” training course, in Alisha Campus,

Riyadh.

Dec 2-3, 2008 “Reviewing and improving your teaching” (Faculty development

Program), Riyadh

Nov10-13, 2008 “TQD (UPLC-MS/MS) Operation and Maintenance course”, Waters

education Headquarter, Manchester, England.

PUBLICATIONS (Peer reviewed)

1. Alanood S. Almurshedi, Mahasen Radwan, Samia Omar, Ayodele A. Alaiya, Mohamed

M. Badran, Hanaa Elsaghire, Imran Y. Saleem, Gillian A. Hutcheon “A novel pH-sensitive

liposome to trigger delivery of afatinib to cancer cells: Impact on lung cancer therapy” J.

Molecular Liquids 259: 154–166 (2018) ISI*

2. Mahasen A. Radwan, Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc,

Matthew Wright Ben Horrock “Oral administration of amphotericin B nanoparticles:

antifungal activity, bioavailability and toxicity in rats” Drug Deliv, 24 (1):40-50 (2017)

ISI*

3. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Ben Horrock, Matthew Wright

“Stealth Amphotericin B Nanoparticles For Oral Drug Delivery: In Vitro Optimization”

Saudi Pharmaceutical Journal, 23 (3):290-302 (2015) ISI*

4. Mahasen A. Radwan, Amal El Sayeh F. Abou el Ela, Maha A. Hassan and Dalia A. El-

Maraghy “Pharmacokinetics and Analgesic Effect and of Ketorolac Floating Delivery

System” Drug Delivery , 22(3): 320–327 (2015) ISI*

5. Bushra T. AL-Quadeib, Mahasen A. Radwan, Lidija Sillerc, Elaine Mutch, Ben Horrock,

Matthew Wright and Abdulaziz Alshaer “Therapeutic Monitoring of Amphotericin B in

Saudi ICU Patients using UPLC MS/MS Assay” Biomedical Chromatography, 28 (12):

1652–1659, (2014) ISI*

6. Mahasen A. Radwan, Nayira A. Abdel Baky, Iman Y. Zaghloul , Hassan Y. Aboul‐Enein,

“Pharmacokinetics and Cardiovascular Effect of Etoricoxib in the Absence or Presence of

St. John's Wort in Rats” ArzneimittelForschun-Drug Research, 62: 313–318 (2012). ISI*

8

7. Mahasen A. Radwan, Esraa S. Al Taweel, Abdulrahman M. Al-Moghairi, Nouf M.

Aloudah, Muneera A. Al Babtain, Hussein S. Al-Amri “Metformin Monitoring in Cardiac

Patients exposed to Contrast Media using UHPLC MS/MS” Therapeutic Drug monitoring,

33:742–749 (2011). ISI*

8. Mahasen A. Radwan, Ghada A. Bawazeer, Nouf M. Aloudah, Bushra T. AlQuadeib,

Hassan Y. Aboul Enein “Determination of Free and Total Warfarin Concentrations in

Plasma Using UPLC MS/MS Assay: Application to Patient Samples” Biomedical

Chromatography, 26: 6–11 (2011). ISI

9. Mahasen A. Radwan, , Bushra T. Alquadeib, Nouf M. Aloudah, Hassan Y. Aboul-Enein

“Pharmacokinetics of Ketorolac Loaded to Polyethylcyanoacrylate Nanoparticles Using

UPLC MS/MS for its Determination in Rats” International Journal of Pharmaceutics

Volume 397(1-2):173-178(2010). ISI

10. Iman Y. Zaghloul, Mahasen A. Radwan, May H. Al Jaser and Ramadan Al Issa “Clinical

Efficacy and Pharmacokinetics of Antimony in Cutaneous Leishmaniasis Patients Treated

With Sodium Stibogluconate”, Journal of Clinical Pharmacology, November

,50(11):12301237(2010). ISI

11. Mahasen A. Radwan, Iman Y. Zaghloul, Nayira A. Abdel Baky “Stability indicating high

performance liquid chromatographic assay for the pharmacokinetics of Cyclooxygenase

(COX-2) inhibitor etoricoxib in rats” African J. of Pharmacy & Pharmacology,

3(7):339346 (2009). ISI

12. Nayira A. Abdel Baky, Nouf M. Al-Rasheed, Nawal M. Al-Rasheed, Iman Y Zaghloul,

and Mahasen A. Radwan “Alpha-lipoic acid and amlodipine ameliorate myocardial

infarction induced by isoproterenol in rats” International Journal of Academic Research, 1

(1): 68-77 (2009).

13. Mahasen A. Radwan, May H. AL Jaser, Zahra R. Al Rayes" The effects of induced

diabetes and cutaneous Leishmania infection on the pharmacokinetics of antimony in

hamsters" Annals of Tropical Medicine & Parasitology, 101 (1):1– 10 (2007). ISI

14. Iman Y. Zaghloul, Mahasen A. Radwan, Zinat H. Aly "The Effect of Chronic Cadmium

Exposure on the Pharmacokinetics of Theophylline and Ciprofloxacin in Rats" J. Trace

Elements in Medicine and Biology, 21:132-137 (2007). ISI

15. May H. AL Jaser, Mahasen A. Radwan, Iman Y. Zaghloul "Pharmacokinetics and tissue

distribution of antimony(v) after multiple intramuscular administrations in the hamster"

Saudi Pharmaceutical Journal, 14: 52-58 (2006). ISI

16. Nahla S. Barakat and Mahasen A. Radwan "In Vitro performance of carbamazepine

loaded to various molecular weights of poly (D, L - lactide - co - glycolide)"; Journal of

Drug Delivery, 13(1):9-18 (2006). ISI

17. Mahasen A. Radwan, Heba H. Abdine, Bushra T. Al-Quadeb, Hassan Y. Aboul-Enein

Kenichiro Nakashima “Steroselective HPLC assay of donepezil enantiomers with UV

detection and its application to Pharmacokinetics in rats” J. Chromatography B,

830:114119 (2006). ISI

9

18. Mahasen A. Radwan, Heba H. Abdine, Hassan Y. Aboul-Enein “A Validated Chiral

HPLC Method for the Determination of Mebeverine HCl Enantiomers in Pharmaceutical

Dosage Forms and Spiked Rat Plasma” Biomedical Chromatography, 20(2):211-216

(2005). ISI

19. Norah O. Abanmy, Msc., Iman Y. Zaghloul, Ph.D., Mahasen A. Radwan, Ph.D.

"Compatibility of tramadol parentral injection with selected drugs and solutions";

American Journal of Health System Pharmacy, 62:1299-1302 (2005). ISI

20. Nouf M. Aloudah, Mahasen A. Radwan, Nasser F. Al Omar and Sydney Jacobs "HPLC

Assay of Fluconazole and its Application to Patients with Early Septic Shock"; J. of Liquid

Chromatography & related Technologies, 28: 591–600 (2005). ISI

21. Hassan Y. Aboul-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Sameer Al-Rawithi

“Biotin dissolution from pharmaceutical dosage forms using an automated hplc system” J.

of Liquid Chromatography & related Technologies, 27:511-519 (2004). ISI

22. Mahasen A. Radwan and Hassan Abu El-Enein, “In Vitro Release and Stereoselective

Disposition of Flurbiprofen Loaded to Poly(D,L-Lactide-Co-glycolide) Nanoparticles in

Rats”. Chirality, 16:119-125 (2004). ISI

23. Al-Jaser, MH, El-Khameesy, SU, Ghannam, MM, Al-Essa, N, Al-Saleh, FM, Al-Garawi,

M, Zaghloul, I, Radwan M, Al Mubbarak, H, Al-Zuhai, H, Al-Garawi, M and AL-Ayed,

M, “Radioactivity Concentration in Surface Soil Samples from Al-Mezahmiah Area,

Southwest of Riyadh, Kingdom of Saudi Arabia”. Egyptian J. Biophysics, 36:4, 727733

(2004).

24. Al-Jaser, MH, El-Khameesy, SU, Ghannam, MM, Al-Saleh, FM, Al-Garawi, M, Zaghloul,

I, Radwan M, Al-Garawi, M, and AL-Ayed, M, “Radioactivity of 226Ra and 40K in the

ground water around Burraydah treatment plant in the northwest of Riyadh, Saudi Arabia”.

Egyptian J. Biophysics, (2003).

25. Magda A. El-Sherbeny, Huda S. Al-Salem, Maha A. Sultan, Mahasen A. Radwan, Hassan

Farag, and Hussein I. El-Subbagh, “Synthesis, in Vitro and in Vivo Evaluation of a Delivery

System for Targeting Anticancer Drugs to the Brain” Pharmazeutische und Medizinische

Chemie, 336:445-455 (2003). ISI

26. Hassan Abu El-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Ahmad Yusuf, Wijdan

AL-Ahmadi, and Sameer Al-Rawithi ”Tamsulosin dissolution from pharmaceutical dosage

forms using an automated hplc system” J. of Liquid Chromatography & related

Technologies, 26:1109-1116 (2003). ISI

27. Mahasen A. Radwan, May H. AL Jaser, Iman Y. Zaghloul, and Shaheen M. Nakeeb

"Pharmacokinetics of Zidovudine and Pentavalent Antimony After Single and Steady State

Administrations In Leishmania Infected Hamsters" Saudi Pharmaceutical Journal, 10:

113-118 (2002). ISI

28. Mahasen A. Radwan and Hassan Y. Aboul-Enein “The effect of various oral absorption

enhancers on the in vivo performance of insulin–loaded poly(ethylcyanoacrylate)

nanospheres in diabetic rats” Journal of microencapsulation, 19:225-235 (2002). ISI

10

29. Mahasen A. Radwan “Enhancement of insulin – loaded polyisobutylcyanoacrylate

nanospheres absorption by sodium cholate after oral and subcutaneous administrations in

diabetic rats Drug Development and Industrial Pharmacy, 27:981-989 (2001). ISI

30. Mahasen A. Radwan and Hassan Y. Aboul-Enein “The effect of absorption enhancers on

the initial degradation kinetics of insulin by -chymotrypsin” International Journal of

Pharmaceutics, 217:111-120 (2001). ISI

31. Mahasen A. Radwan “Preparation and in vivo evaluation of parenteral metoclopramide –

loaded poly(alkylcyanoacrylate) nanospheres in rats” Journal of

Microencapsulation18:467-477(2001). ISI

32. Mahasen A. Radwan, Iman Y. Zaghloul, Badraldin M. Al-Hadiyah, and Khalil I.

AlKhamis “The influence of fluvoxamine administration on glibenclamide

pharmacokinetics after multiple oral dosing in rats” Saudi Pharmaceutical Journal, 8: 116-

121 (2000). ISI

33. Mahasen A. Radwan"Zidovudine, diclofenac, and ketoprofen pharmacokinetic

interactions in rats" Journal Pharmacy and Pharmacology, 52:665-669 (2000). ISI

34. S. Elkheshen and M. A. Radwan ”Sustained release microspheres of metoclopramide

using poly(D,L-lactide-co-glycolide) copolymers” Journal of Microencapsulation,

17(4):425-435 (2000). ISI

35. Mahasen A. Radwan, Iman Y. Zaghloul, and Zinat H. Aly, “In-vivo performance of

parenteral theophylline - loaded polyisobutylcyanoacrylate nanoparticles in rats”

European Journal Pharmaceutical Science, 8:95-98 (1999). ISI

36. Mahasen A. Radwan “Determination of metoclopramide in serum by HPLC assay and its

application to pharmacokinetic study in rat” Analytical Letters, 31 (14): 2397-2410 (1998).

ISI

37. Mahasen A. Radwan, Iman Y. Zaghloul, Ahmed I. Radwan, Zinat H. Aly, “Multiple –

Dose pharmacokinetics of long -acting oxytetracycline in Brucella Melitensis – infected

sheep”, International Journal of Pharmaceutics, 160:91-7 (1998). ISI

38. Iman Y. Zaghloul and Mahasen A. Radwan “High Performance Liquid Chromatographic

Determination of Tramadol in Pharmaceutical Dosage Forms” J. of Liquid

Chromatography, 20:779-87 (1997). ISI

39. Iman Y. Zaghloul, Zinat H. Aly and Mahasen A. Radwan “Effect of Ciprofloxacin on the

Hypoprothrombinemic Activity of Warfarin in Rats”, International Journal of

Pharmaceutics, 131 (2):131-6 (1996). ISI

40. Mahasen A. Radwan, Zinat H. Aly, and Iman Y. Zaghloul, “Effect of Experimental Liver

Damage by CCL4 on the Pharmacokinetics of Zidovudine in Rats” Saudi Pharmaceutical

Journal, 3:90 - 94 (1995). ISI

41. Mahasen A. Radwan “HPLC Assay of Theophylline and Zidovudine in Rat Serum” J. of

Liquid Chromatography, 18 (16):3301-3309 (1995). ISI

11

42. Mahasen A. Radwan “In vitro Evaluation of Polyisobutylcyanoacrylate Nanoparticles

as a Controlled Drug Delivery System of Theophylline”, Drug Development and Industrial

Pharmacy, 21(20): 2371-75 (1995). ISI

43. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, “IN VITRO Release of

Disopyramide from Cellulose Acetate Butyrate Microspheres” Drug Development and

Industrial Pharmacy, 21: 1453-62(1995). ISI

44. M. Radwan “In Vivo Screening Model for Excipients and Vehicles Used in Subcutaneous

Injections”, Drug Development and Industrial Pharmacy, 20: 2753-62 (1994). ISI

45. M.A. Radwan “Stability-Indicating HPLC Assay of Zidovudine in Extemporaneous

Syrup”, Analytical Letters, 27: 1159-1164 (1994). ISI

46. Mahasen A. Radwan, James C. Price, and Randall L.Tackett, "Analysis of Disopyramide

by HPLC with UV Detection", Analytical Letters, 20:1125-31 (1987). ISI

47. H. Won Jun and Mahasen A. Radwan, "Determination of Oxamniquine in Plasma

Samples" Analytical Letters, 18:(1985). ISI

CHAPTERS

1. Mahasen A. Radwan, Nagwa H. Foda, and Omar A. Al Deeb “Mebeverine Hydrochloride”

Analytical Profiles of Drug Substances and Excipients, 25: 165-207 (1998).

2. Nagwa H. Foda, Mahasen A. Radwan, and Omar A. Al Deeb “Fluvoxamine Maleate”

Analytical Profiles of Drug Substances and Excipients, 24:165-208 (1996).

PRESENTATIONS – Abstracts for Oral or Posters

1. M.A. Radwan “Clinical Pharmacokinetics in Egypt: Where we are!” The International

Conference of Faculty of Pharmacy, Egyptian Russian University (ERU): Recent Trends in

Pharmaceutical Sciences” April 28-29, 2018 – Air Defense House Cairo Egypt.

2. M.A. Radwan, Bushra T. ALQuadeib, Lidija Siller, Matthew Wright, Benjamin Horrocks

“Bioavailability and Toxicity of Novel Oral Delivery System of Amphotericin B loaded to

PEGylated Polylactic-Polyglycolic Nanoparticles in Rats”43rd Annual Meeting & Exposition

of the Controlled Release Society, July 17 – 20, 2016, at the Washington State Convention

Center in Seattle, Washington, U.S.A.

3. A.S. Almurshedi, M.A. Radwan, G. Hutcheon, I. Saleem, M. Elkatib “Development of

Novel Pulmonary Liposomal Delivery System of Afatinib Targeting Non-Small Cell Lung

Cancer: In Vitro Characterization” 43rd Annual Meeting & Exposition of the Controlled

Release Society, July 17 – 20, 2016, at the Washington State Convention Center in Seattle,

Washington, U.S.A.

4. Bushra T. ALQuadeib, M.A. Radwan, Lidija Siller, Matthew Wright, Benjamin Horrocks

“Toxicity in rats and in vitro Efficacy of Amphotericin B Nanoparticles formulations” 43rd

Annual Meeting & Exposition of the Controlled Release Society, July 17 – 20, 2016, at the

Washington State Convention Center in Seattle, Washington, U.S.A.

12

5. M. A. Radwan, W. M. Mandour, M. M. El Khatib, I. A. Alsarra Pharmacokinetics of

Pioglitazone Loaded to Buccoadhesive Patches in Dogs Using UPLC MS/MS. AAPS Annual

Meeting, November 10-14, 2013, San Antonio, TX, USA.

6. M. A. Radwan, B. T. al-Quadeib, L. Siller, E. Mutch, A. Alshaer, B. Horrocks, Therapeutic

amphotericin B monitoring in Saudi ICU patients using UPLC MS/MS assay. AAPS Annual

Meeting, November 10-14, 2013, San Antonio, TX, USA.

7. Nayira A. Abdel Baky, Nouf M. Al-Rasheed, Nawal M. Al-Rasheed, Iman Y Zaghloul, and

Mahasen A. Radwan The potential cardioprotective effect of alpha lipoic acid on

isoprotrenol induced myocardial infarction in rats. May 2009 The Joint Meeting of Britches

pharmacological Society: New drugs in pharmacological research, Dresden, Germany,

8. Mahasen Radwan, Amal Fatani, Nouf Alouda “Insulin Oral Delivery of Insulin, Is There A

Hope?” February 2009 1st International Conference on Biotechnology, Riyadh.

9. Mahasen Radwan, Samia Omar "Bioavailability of in situ-gelling and mucoadhesive

ketoconazole liquid suppository in the rat" (R6109) 2006 AAPS Annual Meeting (10/28/2006

- 11/2/2006) San Antonio, TX, USA.

10. Mahsen Radwan, May Al Jaser, Zahra Al Rayes Mohammed Mubarak Pharmacokinetics

and Nephrotoxicity of Pentavalent Antimony after Acute and Chronic Administrations of 80

mg/kg for 3 weeks in the Hamster" (T2335)2006 AAPS Annual Meeting (10/28/2006 -

11/2/2006) San Antonio, TX, USA.

11. Bushra T. Al-Quadeb, Mahasen A. Radwan, Heba H. Abdine, Hassan Y. Aboul-Enein and

Kenichiro Nakashima “Stereoselective HPLC assay of Donepezil Enantiomers in tablets and

plasma and its Application to pharmacokinetics in rats” 9th International Pharmaceutical

Sciences Meeting and Exposition, December 17-21, 2005 in Riyadh, Saudi Arabia.

12. Heba H. Abdine, Mahasen A. Radwan, Hassan Y. Aboul-Enein “A validated chiral HPLC

Method for Method for Determination of Mebeverine HCL Enantiomers in Pharmaceutical

dosage forms and spiked rat plasma.” Podium, 9th International Pharmaceutical Sciences

Meeting and Exposition, December 17-21, 2005 in Riyadh, Saudi Arabia.

13. Mahasen A. Radwan, May H. Al Jaser, Zahra R. Al Rayes "The Effect of InducedDiabetes

and Cutaneous Leishmania infection on the Pharmacokinetics of Antimony(v) after Acute and

Chronic Administrations in the Hamster" April 10-15 (2005). Worldleish 3 –Sicicily –

Palirmo – Italy

14. Mahasen A. Radwan, May H. AL Jaser and Iman Y. Zaghloul "Pharmacokinetics and Tissue

Distribution of Antimony(V) After Multiple Intramuscular Administrations in the Hamster"

Worldleish 3 –Sicicily – Palirmo - Italy April 10-15 (2005).

15. Mahasen A. Radwan, Nouf M. Aloudah “HPLC assay of fluconazole and its application to

patients with early septic shock” Annual Meeting of the American-College-of-

ClinicalPharmacy, OCT 24-27, Dallas, TX, USA (2004). Pharmacotherapy, Volume: 24

Issue: 10: 1460 (Abstract: 268) OCT 2004.

16. Hassan Y. Aboul-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Sameer Al-Rawithi

“Biotin dissolution from pharmaceutical dosage forms using an automated HPLC

system”2004.

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17. M. A. El-Sherbeny, H. S. Al-Salem, M. A. Sultan, M. A. Radwan, H.A. Farag, and H. I. El-

Subbagh, “Design, Synthesis, Investigation of Brain Delivery Model for Anticancer

Compounds” 7th International Conference on Chemistry and its Role in Development.

Mansoura & Sharm El-Sheikh, April 14-17, 2003.

18. Hassan Abu El-Enein, Rajaa F. Hussein, Mahasen A. Radwan, Ahmad Yusuf, Wijdan

ALAhmadi, and Sameer Al-Rawithi”Tamsulosin dissolution from pharmaceutical dosage

forms using an automated hplc system” The 1st International Congress Pharmaceutical &

Drug Industries Division National Research Centre – Towards Safe and active Drug. March

24-26, Cairo Egypt 2003.

19. S. Elkheshen and M. A. Radwan”Sustained release microspheres for metoclopramide using

poly(D,L-lactide-co-glycolide) copolymers of different inherent viscosity” Saudi

Pharmaceutical Society, The Pharmacy Profession in the 21st Century, Riyadh, October

1999.

20. Iman Zaghloul, Mahasen Radwan, Zinat H. Aly, Ahmed I. Radwan, ”Pharmacokinetics of

a

Long - acting Oxytetracycline in Brucella melitensis-infected sheep”, Saudi Biological

Society, Sixteenth Annual Meeting on Biological Natural Resources in Kingdom of Saudi

Arabia, March 1995.

21. Mahasen A. Radwan, Bobby Bryant and Erh Chi Huang, “Development of a Sensitive

HPLC Assay for Lorazepam to Monitor Plasma Levels in Neonates." American Association

of Pharmaceutical Scientists, Washington DC, November, 1991, USA.

22. Mahasen A. Radwan, "HPLC Stability - Indicating Assay of AZT in Liquid Dosage Form."

American Association of Pharmaceutical Scientists, Washington, DC, November, 1991,

USA.

23. D. Goldman, M. Radwan, F. Vane and S. Dixit, "In Vitro and In Vivo Release Characteristics

of Sustained Release Subcutaneous Formulations" American Association of Pharmaceutical

Scientists, Atlanta, October, 1989, USA.

24. Mahasen A. Radwan, David Goldman, Charanjit R. Behl, Saran Kumar, and Sara L.

Friedlander, "Development of In Vitro Release Method For Semisolid Products” American

Association of Pharmaceutical Scientists, Orlando, November, 1988.

25. David Goldman, Mahasen A. Radwan, Suresh C. Dixit, and Peter C. Will, "Evaluation of

InVitro Drug Release From Rectal Preparations" American Association of Pharmaceutical

Scientists, Orlando, November, 1988, USA.

26. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, "In Vitro / In Vivo Correlation

of Disopyramide Oral Sustained Release Formulations, "American Association of

Pharmaceutical Scientists, Orlando, November, 1988.

27. Mahasen A. Radwan, James C. Price, and Randall L. Tackett, "Microencapsulation of

Disopyramide for Oral Sustained Release Dosage" Graduate Research Association of

Students in Pharmaceutics, West Virginia, June, 1987.

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28. Mahasen A. Radwan, James C. Price, and Randall L.Tackett, “Effect of Formulation

Parameters on Characteristics of Cellulose Acetate Butyrate Microcapsules of Disopyramide,

"American Association of Pharmaceutical Scientists, Boston, June, 1987.

29. Mahasen A. Radwan, James C. Price, and Randall L Tackett, “Pharmacokinetic of

Microencapsulated Disopyramide in Dogs" American Association of Pharmaceutical

Scientists, Boston, June, 1987.

30. Mahasen A. Radwan and H.Won Jun, “Pharmacokinetic and Tissue Distribution Studies of

Oxamniquine in Animals" American Association of Pharmaceutical Scientists, Washington

DC, November, 1986.

31. Mahasen A. Radwan and H.Won Jun, "High Performance Liquid Chromatographic

Determination of Oxaminquine in Plasma and Tissue Homogenate" Graduate Research

Association of Students in Pharmaceutics, New Jersey, July, 1985.

EXTRACURRICULAR ACTIVITIES

Besides attending most of the available meetings or conferences (In/out the University Campus),

and the available International Meeting/Conferences (according to our teaching load) the following

is a selection of recent Lectures/Seminars which were given:

February 7, 2016: A 30 min talk of “How to write a research proposal” to my “Future

researcher” group at College of Pharmacy.

January 21, 2016: A two-hour seminar on “Writing a Scientific Research Paper” to the Health

Foundation Year students, Princess Nourah bint Abdulrahman University.

August 25, 2015: A two-hour seminar on “Learn How to Learn” to the Health Foundation Year

students, Princess Nourah bint Abdulrahman University.

June 6, 2015: A three-hour Workshop on “How to use Excel in your work” to all the Health

Foundation Year Staff members, Princess Nourah bint Abdulrahman University.

December 30, 2014: A three-hour workshop of “Factorial Design and SPSS” to TA, lecturers and

Faculty members of College of Pharmacy, Princess Nourah bint Abdulrahman University.

March 14, 2014: A three-hour workshop of “How to publish your research” to Faculty members

of College of Pharmacy, Princess Nourah bint Abdulrahman University.

March 4, 2014: A seminar on “The use of Chi Square in Data Analysis” to Faculty members of

College of Pharmacy, Princess Nourah bint Abdulrahman University.

December 3-5, 2013: Workshop on “SPSS application in Health Sciences” for Faculty members

at Princess Nourah bint Abdulrahman University (A 3-day workshop).

April 2013: Research day workshop for undergraduate students before starting their graduation

research project. College of Pharmacy, Princess Nourah bint Abdulrahman University.

15

April 8-9/2012: Workshop on “Getting Started with SPSS”, for Faculty members at Princess

Nourah bint Abdulrahman University (A 2- day workshop).

May 28- June 1st,2011: Nanotechnology Application Workshop: (Presented three 2-hr lectures

at Princess Nourah bint Abdulrahman University.

February 20, 2011 “An Overview of Zetasizer (nano) Utilization in Pharmaceutical

Applications” a two hour lecture in “Particle characterization by using Zetasizer: Theory and

Application workshop” Al Malaz Central Laboratory.

May 2010: Research day workshop to introduce undergraduate students to research and area of

research available in King Saud University.

March 2009: Workshop: “Clinical Pharmacokinetics Review” at Saudi Pharmaceutical Society

Midyear Meeting, Jeddah.

May, 2008: “Nanotechnology: A New Era in Drug Delivery” Riyadh Military Hospital, Riyadh.

May 7th, 2008: Workshop, "Nanotechnology: A dream or reality in drug delivery and

Cosmetics” King Saud University.

May, 2006: Workshop: "Tips on Getting Published" seminar in "How to Publish?!“ Research

Center King Saud University.

August 1st, 2006. "Clinical Pharmacokinets of Low E Drugs" Lecture in Workshop of "Clinical

Pharmacy for graduate pharmacists“, College of Pharmacy, Cairo University, Egypt,

November 2004: " The effect of deodorants on Human and Environment", Seminar in What

is hazards to your health Symposium at King Saud University, girls section.

July 29, 2003: "Utilization of Polyalkylcyanoacrylate Nanoparticles (PAN) as a Drug Delivery

System" , Seminar, Free University, Berlin, Germany

July, 2003 "Governmental Rules and Regulations for marketing new drugs“ Guest speaker

for 30 minute TV Show "Society and Medication" in Channel 2 Saudi TV. Saudi Arabia

November, 2003: Symposium on “Natural Products Advantages and disadvantages”, lecture on

“Pharmacokinetics of herbal medicine: Gingko Biloba and St. John’s Wort” Seminar in

, King Saud University.

July 13, 2002. A lecure on "Utilization of Polyalkylcyanoacrylate Nanoparticles (PAN) as a

Drug Delivery System". Seminar, Free University, Berlin, Germany.

October 2001: " How to utilize computer in teaching" Workshop offered to faculty members

and teaching assistants and graduate students, King Saud University.

October 23, 2000 “A female pharmacist can make a difference”, Seminar in the University and

Community Week, King Saud University.

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September 27, 1998: "The other face of Deodorants: Cancer and the increase in the heart

beats and difficulty in breathing” National News Paper, AL RIYADH, 11052:

pp. 29.

September, 1998: "Do we have to be worried from using deodorants?" Seminar, King Saud

University

October, 1996: "What the body will do to a drug?" Seminar, King Saud University.

REFERENCES

They will be furnished upon request.