MACROMLECULAR STRUCTURE AND BIOLOGICAL

FUNCTION OF PRIMARY PROTIENS

PRESENTED BYATHIRA P2ND SEM BPSCBPST,KOCHI

CONTENTS

• Definition• Types of protien• Primary protiens• Properties• Functions• Applications

WHAT IS PROTIENSProtiens are the complex nitrogeneous organic compounds in animal and plants.Proteins are polymers of amino acids covalently linked through peptide bonds into a chain.

TYPES OF PROTIEN

GLOBULAR PROTIENS• They are thread like

molecule,lying side by side to form fibers in fibrous protien

• They serve as a chief structural material of animal tissue

• They are insoluble in water,chemically inactive

FIBROUS PROTIENS• In globular protien the

peptide chains are folded,looped and twisted

• So molecule is more or less spherical

• They are soluble in water,chemically active

CLASSIFICATION OF PROTIENS

• Primary protiens• Secondary protiens• Teritiary protiens• Quartanery structure

Primary ProtiensLinear arrangement of aminoacid group in protiens is the primary structure .It is formed by condensation reaction with elimination of water molecule

PHSYCOCHEMICAL PROPERTIES

• water solubility depends on the structure• Protiens are poor soluble in polar solvent

Like ETHANOL, insoluble in nonpolar solvent• Proteins form colloidal solutions colloidal-osmotic pressure = onkotic

pressure• Proteins can be salting-out of the solution• Protiens are ampholytes-COOH -COO- + H+ -NH2 + H+ -NH3+

• proteins strongly absorb UV radiation

• •proteins can be denaturated• heat, whipping, shaking, radiation• strong pH changes, salt of heavy metals,• organic solvents, detergents

FUNCTIONS

• ANTIBODIES• ENZYMES• HORMONS• TRANSPORT• STORAGE• STRUCTURAL PROTIEN• CONTRACTILE PROTIEN

APPLICATIONS

• COATINGS• FILMS IN FOOD PACKAGING• Biotechnology industry protein precipitation

is used to eliminate contaminants commonly contained in blood.

• Used in many foods• Protien microchip isused as biomarker to

identify the tumer cells

• Biomedical application :- hydrogel,scaffold,nanofiber,nanoparticles

• Target drug delivery protien system

SOME APPLICATIONS