M2D2

Connect the Resources of the University of Massachusetts

to Medical Device firms within Massachusetts26 UMass Lowell and 18 UMass Worcester Faculty

Steering Committee – 24 Investment and Industry Leaders

M2D2Massachusetts Medical Device Development Center

UMass Lowell & Worcester

M2D2Massachusetts Medical Device Development Center

UMass Lowell & Worcester

M2D2

WorkforceTraining

ProductRealizationProcess

Incubators/Facilities

BusinessRealizationProcess

Worcester

M2D2 ResourcesM2D2 Resources

• Assistance with:– Defining Market & Business Opportunity– Prototype Development– Clinical Trials Assistance

• Funding• Grant Development, Loans, Investors

• Space• Wet/Dry Labs, Office

• Networks of People & Resources

M2D2

Successful Funding Efforts - NIH SBIR/STTRSuccessful Funding Efforts - NIH SBIR/STTR

$150,000 8 proposals submitted 60% success $2.2MM (ROI > 10 x)A. Develop a “Winning” Proposal / Electronic ApplicationB. “Experts” and Facilities to Insure Success

1. VasoTech Worcester - Lowell, MA $1.2 Million Biodegradable Polymer Drug Eluting Stent

2. Vista Scientific Lawrence, MA $318,000 Nanosphere-Antibiotic Corneal Contact Lens

3. Source Production Andover, MA $500,000 Brachytherapy for Lung Cancer

4. Kazak Woburn, MA $100,000 Portable Jaws of Life

5. Aragon Lowell, MA $100,000 Neuromuscular Biosensor

Fig. 2: VasoTech® Metal Stent

Worcester

M2D2

Matching “FastLane” Loan Fund Matching “FastLane” Loan Fund $500,000 JAII Project Award up to $150K/company

A. Business Assessment / Medical Assessment (15)B. Prototype / Manufacture / Animal & Clinical Trials / IP / FDA (5)

Worcester

Aura Medsystems Lowell, MA Photochemical Tissue Bonding

Oz Technologies Springfield, MA User Friendly Pessary

Smart Surfaces Worcester, MAUlcer Prevention Mattress

MedicaMetrix Wayland, MAProstate Measurement

MoMelan Cambridge, MA Expanded Skin Grafting

Aura MedSystems

Photochemical Tissue Bonding

Mass Life Sciences Accelerator GrantM2D2 FastLane

Aura MedSystems

Photochemical Tissue Bonding

Mass Life Sciences Accelerator GrantM2D2 FastLane

Fig. 3: Patient 20 (lower abdomen)2 weeks 6 months

PTB sutures PTB sutures

VistaVista

A. Topical Ophthalmic Drug Delivery DeviceB. Nanosphere – Antibiotic Corneal Contact Lens

$1,600,000 NIH SBIR Grant

A B

VasoTech

Biodegradable Drug Eluting Stent

$1,200,000 NIH STTR

VasoTech

Biodegradable Drug Eluting Stent

$1,200,000 NIH STTR

SafePathSafePathSafety Suture Needle

Eliminates accidental needle stick

injuries in hospitals.

CMB BiosciencesCMB Biosciences

Electrospun Silk Bandage for Burns

Nano BPSMiniature Fiber Optic Blood Pressure Sensor

Nano BPSMiniature Fiber Optic Blood Pressure Sensor

Coronary angiography following introduction of the UML fiber pressure sensor into the LAD.

Smart Surfaces

Reactive Mattress to Prevent Pressure UlcersM2D2 FastLane Award

Smart Surfaces

Reactive Mattress to Prevent Pressure UlcersM2D2 FastLane Award

MedicaMetrixMedicaMetrix

ProstaGlove – Prostate MeasurementM2D2 FastLane Award

Dartmouth MedicalDartmouth Medical

BIODEGRADABLE CRANIOMAXILLOFACIAL BONDING SYSTEM

Worcester

M2D2

M2D2 Facilities / IncubatorRegional Innovation Center

$4 Million Capital Commitment

M2D2 Facilities / IncubatorRegional Innovation Center

$4 Million Capital Commitment

• Gov. Deval Patrick and Sen. Steven Panagiotakos

Help Establish Innovation Center at UMass Lowell

Worcester

M2D2

M2D2 Facilities / IncubatorRegional Innovation CenterM2D2 Facilities / IncubatorRegional Innovation Center

1. Wannalancit Mill- 1st Floor – Office / Conference (6K s.f.)

2. 333 Aiken St. - Shared Wet Lab Space (6,000 sq ft.)

3. Wannalancit Mill – 2nd Floor- New Offices / Labs / Conf.

(15,000 sq. ft.) - Spring 2011

Worcester

M2D2

M2D2 Steering CommitteeIndustry Focused & Engaged M2D2 Steering Committee

Industry Focused & Engaged