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Long term results of expanding prostheses for limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice Service d’Oncologie Pédiatrique –Hôpital Universitaire France. GARCHES www.nicoledelepine.fr

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Page 1: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term results of

expanding prostheses for

limb salvage surgery in

children with bone tumors Communication présentée à l’EFORT 2008 Nice

Service d’Oncologie Pédiatrique –Hôpital Universitaire France. GARCHES

www.nicoledelepine.fr

Page 2: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

4

36

5

5

proximal femur 4

total femur 5

distal femur 36

upper tibia 5. Osteos. Ewing MFH

Histology and Locations of

tumors

Page 3: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

• In 18 patients, the expanding prosthesis was inserted immediately

after the resection,in 9 during the following year

27 early prosthesis implantation

Page 4: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

23 secondary implantations to

treat leg length discrepancy.

Page 5: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

• Consists of a tibial and

femoral component

joined by a metal on

polyethylene hinge .

• The lengthening

mechanism is contained

in the part of the

prosthesis which replaces

the tumor.

Active expanding prosthesis

Page 6: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

The tibial passive part for femoral tumor

6 years after

implantation the

tibial growth is

similar to the

controlateral

side

Page 7: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

The femoral passive part for tibial tumors

8 years after

implantation

the femoral

growth is

similar to the

controlateral

side

Page 8: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Morse taper unlimited lengthening

with 1 then 2 extra rods

Page 9: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

The generation 1 « open sky prosthetic mechanism »used a threaded rock which was turned by a screw driver inserted into the knee in the line of the femur.

cement

Screw

driver

It was insufficiently stable to maintain position and had to be reinforced by using a wedge of acrylic cement.

The open sky prosthetic mechanism

Zimmer Delepine (ZD1)

Page 10: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

the arthroscopic prosthesis

– a better anticollapse device

– elongation is produced arthroscopically using

small puncture incisions

Page 11: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

magnetic prosthesis

Soubiran - Delepine (SD3)

• The generation 3 prosthesis

depends on a compressed spring

which can be adjusted by using

magnetic stimulation applied

externally.

• As there is no need for any

incision lengthening, it can be

achieved in stages, each of a few

millimeters.

Magnetic field generator

Lengthening stage

Page 12: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Elongation of a magnetic

prosthesis for distal femur( SD3 )

10 centimeters lengthening in 9 months

Page 13: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Aspect of elongation of a magnetic

prosthesis for proximal tibia (SD3)

Page 14: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Deep infection Spontaneous skin

breakdown Antibiotics loaded spacers

For tibia For femur

Page 15: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

trophic sequellaes

if we obtain a usually a good lenght, the

lenghtening can lead to trophic sequellaes

Page 16: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

late functional result

(according to EMSOS criteria)

• Excellent 10

• Good 15

• Fair 10 (total femoral reconstruction and stiff knees)

• poor 5 (among them 4 secondary amputations)

Page 17: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Upper Tibial Ewing’s Sarcoma with 3 skip

metastases on NMR. Bifocal Resection.

bifocal Resection

T

Page 18: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

2007,18 years

after resection

1989 Osteosarcoma in a 4 years old boy

Page 19: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

4 years old girl

01 1985 03 1984

Page 20: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

:Osteosarcoma in a

7 years old girl.

6 interventions lengthening 6 cms.

May 2007

May 1990

1994

Page 21: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

osteosarcoma of the proximal tibia

in a 10 y old girl (13 Y FU)

1992

1994 1997 Expanding tibial

prosthesis (T SD3)

8/2007

Allograft composite P

Page 22: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Bipolar Resection

Distal femur expandable

prosthesis

7 years later

Page 23: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

After large lengthening bone

stock may become insufficiant

• Patient treated for

osteosarcoma of

proximal tibia when

she was 9 years old.

• 10 years later and after

6 operations the

proximal part of femur

became too small.

Page 24: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

In these cases we advocate to reconstruct

the bone defect with an allograft

Page 25: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

CONCLUSION :

The expandable prosthesis provides an effective alternative to amputation for about 80% young children .

But the number of operations is high for large lengthening

with a high rate of infection, frequent stiffness of the knee, and at the adult age , poor trophicity of the limb and

bone stock frequently insuffisant.

Page 26: Long term results of expanding prosthesis for limb salvage ... · limb salvage surgery in children with bone tumors Communication présentée à l’EFORT 2008 Nice ... and at the

Long term follow up of Expanding prosthesis EFORT 2008 Nice

Conclusion 2

• When a prosthesis of the kne is planned in a young child.

• avoiding sterilization of the growing plate of the unaffected side of the articulation is mandatory.

Patient treated for an

osteosarcoma of

proximal tibia when he

was 13.