LiverLiver

PancreasPancreas

Function of liverFunction of liver::

1. 1. Syntesis:Syntesis:Bile Bile Plasma proteinePlasma proteinePlasma lypoproteines (vitamine K, D, E, A, Plasma lypoproteines (vitamine K, D, E, A, cholesterine)cholesterine)

2. 2. Detoxication Detoxication 3. 3. Destruction of spent red cell and Destruction of spent red cell and

reclamation of their constituensreclamation of their constituens4. 4. Universal haemopoetic organUniversal haemopoetic organ5. Endocrine - somatomedine5. Endocrine - somatomedine

Liver vasculatureLiver vasculature

LIVER & Pancreas

LIVER

Bile

Hepatic artery

Portal vein

GI wormHepatic veins

Liver is the blood-processing glandular intermediary between you and your G-I worm (tract) that determines blood quality in two ways METABOLIC by Hepatocytes PROTECTIVE by Kupffer cells (Ms)

W Beresford

Liver lobuleLiver lobule

Liver specimenLiver specimen

Liver specimensLiver specimens

HEPATIC PARENCHYMA epithelial working tissue

Plate of hepatocytes

SINUSOID

Plate of hepatocytes

Endothelial cells

SpaceSINUSOID

Kupffer cellblood

CELL TYPES & ARRANGEMENT OF LIVER

Microvilli

Hepatocytes in plates

Bile canaliculus SPACE OF DISSE

Fenestrated Endothelial cells

SINUSOID Kupffer cell

STELLATE CELL

HEPATOCYTE ENDOTHELIAL CELL KUPFFER CELL STELLLATE CELL

Hepatocyte, blood capilaries, bile canaliculusHepatocyte, blood capilaries, bile canaliculus

HepatocyteHepatocyte

bile canaliculusbile canaliculus

Hepatocyte, blood capilaries, bile canaliculusHepatocyte, blood capilaries, bile canaliculus

Schema of clasiccal and portal lobules Schema of clasiccal and portal lobules and liver acinusand liver acinus

gallbladdergallbladder

Epithelium of gallbladderEpithelium of gallbladder

pancreaspancreas

Acinus and duct of pancreasAcinus and duct of pancreas

Homogenic and zymogenic zonesHomogenic and zymogenic zones

pancreatocytepancreatocyte

Langerhans isletsLangerhans islets

Classification of insulocytesClassification of insulocytes::

В- В- insulocytesinsulocytes – – insulininsulin

А- А- insulocytesinsulocytes– – glucagonglucagon

DD- - insulocytesinsulocytes– – somatostatinsomatostatin

DD11--insulocytesinsulocytes– – VIPVIP ( (vasoactivevasoactive intestinal intestinal

peptidepeptide))

РРРР or F or F--insulocytesinsulocytes– – pancreaticpancreatic polypeptidepolypeptide

В і А інсулоцити в складі острівця ЛангергансаВ і А інсулоцити в складі острівця Лангерганса

ІНСУЛОЦИТИ і ГЕМОКАПІЛЯР /схема/ІНСУЛОЦИТИ і ГЕМОКАПІЛЯР /схема/