list of publications david nadal, born - universit¤t z¼rich

LIST OF PUBLICATIONS David Nadal, born 18.04.1954 January 10, 2014

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Dissertation Das Menkes-Syndrom: Literaturübersicht und Darstellung zwei eigener Fälle. Med. Diss., Zürich, 1985. PUBLICATIONS a) Original Papers 1. Nadal D, Plüss H-J, Jörg W, Hitzig WH. Das Hypereosinophiliesyndrom bei akuter lymphatischer

Leukämie. Schweiz Med Wochenschr 1986;116:1151-1154. 2. Nadal D, Boltshauser E. Transient paraparesis following bacterial meningitis. Helv paediat Acta

1987;42:55-57. 3. Nadal D, Baerlocher K. Menkes disease: long-term treatment with copper and D-penicillamine. Eur J

Pediatr 1988;147:621-625. 4. Nadal D, Gundelfinger R, Flueler U, Boltshauser E. Acrodermatitis chronica atrophicans. Arch Dis

Child 1988;63:72-74. 5. Nadal D, Schwöbel M, von Graevenitz A. Corynebacterium group D and urolithiasis in a boy with

megacalycosis. Infection 1988;16:245-247. 6. Jendis JB, Tomasik Z, Hunziker U, Nadal D, Seger R, Wetzel J-C, Kind Ch, Schüpbach J. Evaluation of

diagnostic tests for HIV infection in infants born to HIV-infected mothers in Switzerland. AIDS 1988;2:273-279.

7. Bernasconi C, Nadal D, Wüst J, Lips U, Boltshauser E. Food-borne botulism: an uncommon disorder.

Helv paediat Acta 1988;43:515-519. 8. Hunziker UA, Nadal D, Jendis JB, Tomasik Z, Wetzel JC, Schüpbach J, Seger R. Stable HIV-

encephalopathy in two infants receiving early intravenous gammaglobulin plus antimicrobial prophylaxis. Eur J Pediatr 1989;148:417-422.

9. Nadal D, Hunziker UA, Bucher HU, Hitzig WH, Duc G. Infants born to mothers with antibodies against

Borrelia burgdorferi at delivery. Eur J Pediatr 1989;148:426-427. 10. Nadal D, Hunziker UA, Schüpbach J, Wetzel J-C, Tomasik Z, Jendis JB, Fanconi A, Seger RA.

Immunological evaluation in the early diagnosis of prenatal or perinatal HIV infection. Arch Dis Child 1989;64:662-669.

11. Nadal D, Leppert D, Frei K, Gallo P, Lamche H, Fontana A. Tumor necrosis factor in infectious

meningitis. Arch Dis Child 1989;64:1274-1279. 12. Bucher HU, Nadal D, Mieth D. Listeriose beim Neugeborenen: Bessere Prognose dank Früherkennung.

Monatsschr Kinderheilkd 1989;137:321-325. 13. Nadal D, Taverna Ch, Hitzig WH. Immunoblot analysis of antibody binding to polypeptides of Borrelia

burgdorferi in children with different clinical manifestations of Lyme disease. Pediatr Res 1989;26:377-382.

14. Nadal D, Wunderli W, Briner H, Hansen K. Prevalence of antibodies to Borrelia burgdorferi in forestry

workers and blood donors from the same region in Switzerland. Eur J Clin Microbiol Infect Dis 1989;8:992-995.

15. Nadal D, Hunziker UA, Bauersfeld U, Pfister H, Hitzig WH. Infection with Staphylococcus aureus

producing toxic shock syndrome (TSS) toxin-1 without TSS. Eur J Pediatr 1989;148:318-319.


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16. Nadal D, Wunderli W, Meurmann O, Briner J, Hirsig J. Isolation of respiratory syncytial virus from liver tissue and extrahepatic biliary atresia material. Scand J Infect Dis 1990;22:91-93.

17. Nadal D, Herrmann P, Baumann A, Fanconi A. Acute mastoiditis: clinical, microbiological, and

therapeutic aspects. Eur J Pediatr 1990;149:560-564. 18. Nadal D, Albini B, Chen C, Schläpfer E, Bernstein JM, Ogra PL. Distribution and engraftment patterns

of human tonsillar mononuclear cells in mice with severe combined immunodeficiency: Role of the Epstein-Barr virus. Int Arch Allergy Appl Immunol 1991;95:341-351.

19. Nadal D, Albini B, Schläpfer E, Chen C, Brodsky L, Ogra PL. Tissue distribution of mucosal antibody-

producing cells specific for respiratory syncytial virus in scid mice engrafted with human tonsils. Clin Exp Immunol 1991;85:358-364.

20. Yalman N, Brändle B, Greiner J, Rutishauser M, Mühlebach TL, Hunziker UA, Nadal D, Schüpbach J,

Seger RA. Depression of antigen-specific immune responses: an early feature preceding symptoms in vertical HIV-infection. Immunology and Infectious Diseases 1991;1:275-280.

21. Nadal D, Albini B, Schläpfer E, Bernstein JM, Ogra PL. Role of Epstein-Barr virus and interleukin-6 in

the development of lymphomas of human origin in SCID mice engrafted with human tonsillar mononuclear cells. J Gen Virol 1992;73:113-121.

22. Chen C, Nadal D, Cohen SA, Mookerjee B, Vladutiu A, Stinson MW, Ogra PL, Albini B. Direct

demonstration of engraftment of human peripheral blood leukocytes (hu-PBL) in SCID mice. Int Arch Allergy Appl Immunol 1992;97:295-300.

23. Nadal D, Soh N, Schläpfer E, Bernstein JM, Ogra PL. Distribution characteristics of immunoglobulin-

secreting cells in adenoids. Relationship to age and disease. Int J Pediatr Otolaryngol 1992;24:121-130.

24. Soh N, Nadal D, Schläpfer E, Bernstein JM, Ogra PL. Immunologic response of adenoidal lymphocytes

to respiratory syncytial virus. Ann Otol Rhinol Laryngol 1992;101:848-853. 25. Nadal D, de Roche B, Buisson M, Seger RA. Oral hairy leukoplakia in vertically and horizontally

acquired HIV infection. Arch Dis Child 1992;67:1296-1297. 26. Nadal D, Caduff R, Kraft R, Salfinger M, Bodmer T, Kirschner P, Böttger EC, Schaad UB. Invasive

infection with Mycobacterium genavense in three children with the acquired immunodeficiency syndrome. Eur J Clin Microbiol Infect Dis 1993;12:37-43.

27. Nadal D, Lauener RP, Braegger CP, Kaufhold A, Simma B, Lütticken R, Seger RA. T cell activation and

cytokine release in streptococcal toxic shock-like syndrome. J Pediatr 1993;122:727-729. 28. Nadal D, von Graevenitz A. Routine detection of inducible ß-lactamase in gram-negative bacilli by

means of disk susceptibility testing. J Microbiol Methods 1993;17:283-291. 29. Weber R, Sauer B, Lüthi R, Nadal D. Intestinal coinfection with Enterocytozoon bieneusi and

Cryptosporidium in a human immunodeficiency virus-infected child with chronic diarrhea. Clin Infect Dis 1993;17:480-483.

30. Richard B, Nadal D, Meuli M, Braegger CP. Acute acalculous cholecystitis in infective endocarditis. J

Pediatr Gastroenterol Nutr 1993;17:215-216. 31. Frei K, Nadal D, Pfister H-W, Fontana A. Listeria meningitis: identification of a cerebrospinal fluid

inhibitor of macrophage listericidal function as interleukin 10. J Exp Med 1993;178:1255-1261. 32. Knecht H, Bachman E, Brousset P, Sandvej K, Nadal D, Bachman F, Odermatt BF, Delsol G, Pallesen

G. Deletions within the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma. Blood 1993;82:2937-2942.


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33. Waldvogel K, Regnery RL, Anderson BE, Caduff R, Caduff J, Nadal D. Disseminated cat-scratch disease: detection of Rochalimaea henselae in affected tissue. Eur J Pediatr 1994;153:23-27.

34. Nadal D, Caduff R, Frey E, Hassam S, Zimmermann DR, Seigneurin J-M, Plüss H-J, Seger RA. Non-

Hodgkin's lymphoma in four children infected with the human immunodeficiency virus: association with Epstein-Barr virus and treatment. Cancer 1994;73:224-230.

35. Gruner E, Bernasconi E, Galeazzi RL, Buhl D, Heinzle R, Nadal D. Brucellosis: an occupational hazard

for medical laboratory personnel. Report of five cases. Infection 1994;22:33-36. 36. Glarner H, Meuli M, Hof E, Galatti V, Nadal D, Fisch U, Stauffer UG. Management of petrous bone

fractures in children: Analysis of 127 cases. J Trauma 1994;36:198-201. 37. Braegger CP, Nadal D. Clarithromycin and pseudomembranous enterocolitis. Lancet 1994;343:241-

242. [Letter]

38. Kluger G, Schöttler A, Waldvogel K, Nadal D, Hinrichs W, Wündisch GF, Laub MC. Tickborne encephalitis despite specific immunoglobulin prophylaxis. Lancet 1995;346:1502. [Letter]

39. Jacquier P, Nadal D, Zuber P, Eckert J. Zur Lage der Infektion mit Toxoplasma gondii bei der

schweizerischen Bevölkerung: Beitrag einer seroepidemiologischen Studie aus dem Kanton Zürich. Schweiz Med Wochenschr 1995;125 (Suppl.65):23S-28S.

40. Guzman J, Frei K, Nadal D. In vitro immunization: generation of neutralizing monoclonal antibodies to

human interleukin-10. J Immunol Meth 1995;179:265-268. 41. Braegger CP, Albisetti M, Nadal D. Extensive esophageal candidiasis in the absence of oral lesions in

pediatric AIDS. J Pediatr Gastroenterol Nutr 1995;21:104-106. 42. Berger Ch, Albisetti M, Fanconi S, Rudin Ch, Cheseaux JJ, Micallef J, Kind C, Nadal D. Pneumocystis-

carinii-Pneumonie bei Säuglingen mit vertikaler HIV-Infektion in der Schweiz. Schweiz Med Wochenschr 1995;125:1162-1167.

43. Lauener RP, Hüttner S, Buisson M, Hossle JP, Albisetti M, Seigneurin J-M, Seger RA, Nadal D. T-cell

death by apoptosis in vertically HIV-infected children coincides with expansion of CD8+/interleukin-2 receptor-/HLA-DR+ T cells: sign of a possible role for herpes viruses as cofactors? Blood 1995;86:1400-1407.

44. Nadal D, Zbinden R. Serology to Bartonella (Rochalimaea) henselae may replace traditional diagnostic

criteria for cat-scratch disease. Eur J Pediatr 1995;154:906-908. 45. Zbinden R, Höchli M, Nadal D. Intracellular location of Bartonella henselae cocultivated with Vero cells

and used for an indirect fluorescent-antibody test. Clin Diag Lab Immunol 1995;2:693-695. 46. Solèr RA, Migliorati C, van Waes H, Nadal D. Thalidomide treatment of mucosal ulcerations in HIV

infection. Arch Dis Child 1996;74:64-65. 47. Neuhaus TJ, Iselin H, Nadal D. Haemophilus influenzae: a cause of peritonitis in peritoneal dialysis.

Nephrol Dial Transplant 1996;11:199-200. 48. Berger Ch, Pfyffer GE, Nadal D. Treatment of nontuberculous mycobacterial lymphadenitis with

clarithromycin plus rifabutin. J Pediatr 1996;128:383-386. 49. Berger Ch, Braegger CP, Albisetti M, Landau K, Nadal D. Cerebral tuberculosis presenting as complex

febrile convulsions. Neuropediatrics 1996;27:161-163. 50. Stricker T, Willi UV, Pfyffer GE, Nadal D. A school-girl with constipation. Lancet 1996;348:306. 51. Waldvogel K, Bossart W, Huisman T, Boltshauser E, Nadal D. Severe tick-borne encephalitis following

passive immunization. Eur J Pediatr 1996;155:775-779.


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52. Solèr RA, Howard M, Brink NS, Gibb D, Tedder RS, Nadal D. Regression of AIDS-related Kaposi’s sarcoma during therapy with thalidomide. Clin Infect Dis 1996;23:501-503.

53. Ruef C, Fanconi S, Nadal D. Sternal wound infection after heart operations in pediatric patients

associated with nasal carriage of Staphylococcus aureus. J Thorac Cardiovasc Surg 1996;112:681-686.

54. Steinlin MI, Nadal D, Eich GF, Martin E, Boltshauser EJ. Late intrauterine cytomegalovirus infection:

Clinical and neuroimaging findings. Pediatr Neurol 1996;15:249-253. 55. Nadal D, Guzman J, Fröhlich S, Braun DG. Human immunoglobulin preparations suppress the

occurrence of Epstein-Barr virus-associated lymphoproliferation. Exp Hematol 1997;25:223-231. 56. Spanaus K-S, Nadal D, Pfister H-W, Seebach J, Widmer U, Frei K, Gloor S, Fontana A. C-X-C and C-C

chemokines are expressed in the cerebrospinal fluid in bacterial meningitis and mediate chemotactic activity on peripheral blood-derived polymorphonuclear and mononuclear cells in vitro. J Immunol 1997;158:1956-1964.

57. Richner B, Laurent D, Sunnarat Y, Bee D, Nadal D. Spread of HIV-1 to children in Cambodia. Lancet

1997;349:1451-1452. 58. Stahel PF, Nadal D, Pfister H-W, Paradisis PM, Barnum SR. Complement C3 and factor B

cerebrospinal fluid concentrations in bacterial and aseptic meningitis. Lancet 1997;349:1886-1887. 59. Albisetti M, Schaer G, Good M, Boltshauser E, Nadal D. Diagnostic value of cerebrospinal fluid

examination in children with peripheral facial palsy and suspected Lyme borreliosis. Neurology 1997;49:817-824.

60. Zbinden R, Michael N, Sekulovski M. von Graevenitz A. Nadal D. Evaluation of commercial slides for

detection of immunoglobulin G against Bartonella henselae by indirect immunofluorescence. Eur J Clin Microbiol Infect Dis 1997;16:648-652.

61. Lahrtz F, Piali L, Nadal D, Pfister H-W, Spanaus K-S, Baggiolini M, Fontana A. Chemotactic activity on

mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-γ inducible protein-10 and monocyte chemotactic protein-1. Eur J Immunol 1997;27:2484-2489.

62. Berger C, McQuain, C, Sullivan JL, Nadal D, Quesenberry PJ, Knecht H. The 30-bp deletion variant of

Epstein-Barr virus-encoded latent membrane protein-1 prevails in acute infectious mononucleosis. J Infect Dis 1997;176:1370-1373.

63. Kind C, Rudin C, Siegrist C-A, Wyler C-A, Biedermann K, Lauper U, Irion O, Schüpbach J, Nadal D,

and the Swiss Neonatal HIV-Study Group. Prevention of vertical HIV transmission: additive protective effect of elective cesarean section and zidovudine prophylaxis. AIDS 1998;12:205-210.

64. Stricker T, Fröhlich S, Nadal D. Osteomyelitis and septic arthritis due to Citrobacter freundii and

Haemophilus influenzae type b. J Paediatr Child Health 1998;34:90-91. 65. Zbinden R, Ströhle A, Nadal D. IgM to Bartonella henselae in cat-scratch disease and during acute

Epstein-Barr virus infection. Med Microbiol Immunol 1998;186:167-170. 66. Kolb SA, Lahrtz F, Paul R, Leppert D, Nadal D, Pfister H-W, Fontana A. Matrix metalloproteinases and

tissue inhibitor of mettalloproteinases in viral meningitis: upregulation of MMP-9 and TIMP-1 in cerebrospinal fluid. J Neuroimmunol 1998;84:143-150.

67. Stricker T, Steinlin M, Willi UV, Nadal D. Hypoglossal nerve palsy associated with deep cervical

lymphadenopathy. Neurology 1998;50:1926-1927. 68. Bossart W, Nadal D. Intrauterine rubella virus infection despite anticipated maternal immunity. Eur J

Clin Microbiol Infect Dis 1998;17:597-599.


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69. Ozsahin H, von Planta M, Müller I, Steinert HC, Nadal D, Lauener R, Tuchschmid P, Willi UV, Ozsahin M, Crompton NEA, Seger RA. Successful treatment of invasive aspergillosis in chronic granulomatous disease by bone marrow transplantation, G-CSF mobilized granulocytes, and liposomal Amphothericin-B. Blood 1998;92:2719-2724.

70. Nadal D, Steiner F, Cheseaux JJ, Rudin C, Paediatric AIDS Group of Switzerland. Ritonavir promotes

increased growth in HIV-infected children. AIDS 1998;12:2356-2357. 71. Schmitt B, Wohrab G, Steinlin M, Fanconi S, Nadal D, Boltshauser E. Treatment with the N-methyl-D-

aspartate receptor antagonist dextromethorphan in severe bacterial meningitis: preliminary results. Eur J Pediatr 1998;157:863-865.

72. Fischer JE, Janousek M, Nadal D, Fanconi S. Diagnostic techniques for ventilator-associated

pneumonia. Lancet 1998;352:1066. [Letter] 73. Huisman TA, Wohlrab G, Nadal D, Boltshauser E, Martin E. Unusual presentations of neuroborreliosis

in childhood. J Comput Assist Tomogr 1999;23:39-42. 74. Berger C, Rothenberger S, Bachmann E, McQuain C, Nadal D, Knecht H. Sequence polymorphisms

between latent membrane proteins LMP1 and LMP2A do not correlate in EBV-associated reactive and malignant lymphoproliferations. Int J Cancer 1999;81:371-375.

75. Zingg W, Bossart W, Berli E, Nadal D. Detection and quantification of cell-free Epstein-Barr virus by

polymerase chain reaction and subsequent DNA enzyme immuno assay. J Virol Methods 1999;79:141-148.

76. Zbinden R, von Graevenitz A, Rossi J, Kümin E, Berger-Bächi B, Hächler H, Nadal D. False positive β-

lactamase results with Staphylococcus lugdunensis in the Vitek AutoMicrobic System. Zentralbl Bakteriol 1999;289:365-370.

77. Nadal D, Böni J, Kind C, Varnier OE, Steiner F, Tomasik Z, Schüpbach J. Prospective evaluation of

amplification-boosted ELISA for heat-denatured p24 antigen for diagnosis and monitoring of pediatric human immunodeficiency virus type 1 infection. J Infect Dis 1999;180:1089-95.

78. Albisetti M, Braegger CP, Stallmach T, Willi UV, Nadal D. Hepatic steatosis: A frequent non-specific

finding in HIV-infected children. Eur J Pediatr 1999;158:971-974. 79. Michel K, Albisetti M, Pfyffer GE, Nadal D. Sporadic tuberculous meningoencephalitis. Infection

1999;27:370-371. 80. Nadal D, Berger C, Aebi C, Kind C. Prophylaxis for respiratory syncytial virus bronchiolitis. Lancet

1999;354:1997. [Letter] 81. Hardegger D, Nadal D, Bossart W, Altwegg M, Dutly F. Rapid detection of Mycoplasma pneumoniae in

clinical samples by real-time PCR. J Micobiol Methods 2000;41:45-51. 82. Fischer JE, Brunner A, Janousek M, Nadal D, Blau N, Fanconi S. Diagnostic potential of neutrophil

elastase inhibitor complex in the routine care of critically ill newborn infants. Eur J Pediatr 2000;159:659-662.

83. Meuli M, Lips U, Nadal D. A toddler with burns, stomatitis, and skin graft loss. Burns 2000;26:625-627. 84. Nadal D, Steiner F, Cheseaux JJ, Wyler Lazarevitch CA, Aebi C, Kind C, Rudin C, Pediatric AIDS

Group of Switzerland. Long-term responses to treatment including ritonavir or nelfinavir in HIV-1-infected children. Infection 2000;28:287-296.

85. Fischer JE, Ramser E, Altermatt S, Nadal D, Waldvogel K. Rationaler Einsatz von Antibiotika beim

kritisch kranken Kind. Schweiz Med Wochenschr 2000;130:1564-1571.


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86. Schüpbach J, Tomasik Z, Nadal D, Ledergerber B, Flepp M, Opravil M, Böni J. Use of HIV-1 p24 as a sensitive, precise and inexpensive marker for infection, disease progression and treatment failure. J Antimicrob Agents 2000;16:441-445.

87. Nadal D, Bossart W, Zucol F, Steiner F, Berger C, Lips U, Altwegg M. Community-acquired pneumonia

in children due to Mycoplasma pneumoniae: Diagnostic performance of a seminested 16S rDNA-PCR. Diagn Microbiol Infect Dis 2001;39:15-19.

88. Benador D, Neuhaus TJ, Papazyan J-P, Willi UV, Engel-Bicik I, Nadal D, Slosman D, Mermillod B,

Girardin E. Randomised controlled trial of three day versus 10 day intravenous antibiotics in acute pyelonephritis: effect on renal scarring. Arch Dis Child 2001;84:241-246.

89. Huisman TAGM, Holzmann D, Nadal D. MRI of chronic recurrent parotitis in childhood. J Comput

Assist Tomogr 2001;25:269-273. 90. Berger C, Day P, Meier G, Zingg W, Bossart W, Nadal D. Dynamics of Epstein-Barr Virus (EBV) DNA

levels in serum during EBV-associated disease. J Med Virol 2001;64:505-512. 91. Greiner O, Day P, Bosshard P, Imeri F, Altwegg M, Nadal D. Quantitative Detection of Streptococcus

pneumoniae in nasopharyngeal secretions by real-time PCR. J Clin Microbiol 2001;39:3129-3134. 92. Güngör T, Engel-Bicik I, Eich G, Willi UV, Nadal D, Hossle JP, Seger RA, Steinert HC. Diagnostic and

therapeutic impact of whole body positron emission tomography using fluorine-18-fluoro-2-deoxy-D-glucose in children with chronic granulomatous disease. Arch Dis Child 2001;85:341-345.

93. Abels S, Nadal D, Stroehle A, Bossart W. Reliable detection of respiratory syncytial virus infection in

children for adequate hospital infection control management. J Clin Microbiol 2001;39:3135-3139. 94. Steiner F, Kind C, Aebi C, Wyler-Lazarevitch CA, Cheseaux JJ, Rudin C, Molinari L, Nadal D. Growth in

human immunodeficiency virus type 1-infected children treated with protease inhibitors. Eur J Pediatr 2001;160:611-616.

95. Holzmann D., Willi U., Nadal D. Allergic Rhinitis as a risk factor for orbital complication of acute

Rhinosinusitis in children. Am J Rhinology 2001;15:387-390. 96. Berger C, Altwegg M, Meyer A, Nadal D. Broad-range polymerase chain reaction for diagnosis of rat-

bite fever caused by Streptobacillus moniliformis. Pediatr Infect Dis J 2001;20:1181-1182 97. Fleisch F, Zimmermann-Baer U, Zbinden R, Bischoff G, Arlettaz R, Waldvogel K, Nadal D, Ruef C.

Three consecutive outbreaks of Serratia marcescens in a neonatal intensive care unit. Clin Infect Dis 2002;34:767-773

98. Nadal D, Blasius M, Niggli FK, Meier G, Berger C. Epstein-Barr virus (EBV) DNA levels in palatine

tonsils and autologous serum from EBV carriers. J Med Virol 2002;67:54-58. 99. Cheseaux JJ, Jotterand V, Aebi C, Gnehm H, Kind C, Nadal D, Rudin C, Wyler Lazarevitch CA, Nicod

P, Mooser V. Hyperlipidemia in HIV-infected children treated with protease inhibitors: Relevance for cardiovascular diseases. J Acquir Immune Defic Syndr 2002;30:288-293.

100. Fischer JE, Benn A, Harbarth S, Nadal D, Fanconi S. Diagnostic accuracy of G-CSF, IL-8, and IL-1ra in

critically ill children with suspected infection. Intensive Care Med 2002;28:1324-1331. 101. Nadal D, Leverger G, Sokal EM, Floret D, Perel Y, Leibundgut K, Weller S. An investigation of the

steady-state pharmacokinetics of oral valacyclovir in immunocompromised children. J Infect Dis 2002;186 (Suppl 1):S123-30.

102. Fischer JE,, Steiner F, Zucol F, Berger C, Martignon L, Bossart W, Altwegg M, Nadal D. Use of simple

heuristics to target macrolide prescription in children with community-acquired pneumonia. Arch Pediatr Adolesc Med 2002;156:1005-1008.


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103. Greiner O, Berger C, Day PJR, Meier G, Tang CM, Nadal D. Rates of detection of Neisseria meningitidis in tonsils differ in relation to local incidence of invasive disease. J Clin Microbiol 2002;40:3917-3921.

104. Holzmann D, Funke G, Linder T, Nadal D. Turicella otitidis and Corynebacterium auris do not cause

otitis media with effusion in children. Pediatr Infect Dis J 2002;21:1124-1126. 105. Fieschi C, Dupuis S, Catherinot E, Feinberg J, Bustamante J, Breiman A, Altare F, Baretto R, Le Deist

F, Kayal S, Koch H, Richter D, Brezina M, Aksu G, Wood P, Al-Jumaah S, Raspall M, da Silva Duarte AJ, Tuerlinckx D, Virelizier J-L, Fischer A, Enright A, Bernhöft J, Cleary AM, Vermylen C, Rodriguez-Gallego C, Davies G, Blütters-Sawatzki R, Siegrist C-A, Ehlayel MS, Novelli V, Haas WH, Levy J, Freihorst J, Al-Hajjar S, Nadal D, de Moraes Vasconcelos D, Jeppsson O, Kutukculer N, Frecerova K, Caragol I, Lammas D, Kumararatne DS, Abel L, Casanova J-L. Low penetrance, broad resistance, and favorable outcome of Interleukin 12 receptor β1 deficiency: Medical and immunological implications. J Exp Med 2003;197:527-535.

106. Greiner O, Day PJR, Altwegg M, Nadal D. Quantitative detection of Moraxella catarrhalis in

nasopharyngeal secretions by real-time PCR. J Clin Microbiol 2003;41:1386-1390. 107. Bonanomi A, Dohm C, Rickenbach Z, Altwegg M, Fischer J, Gygi D, Nadal D. Monitoring intracellular

replication of Chlamydophila (Chlamydia) pneumoniae in cell cultures and comparing clinical samples by real-time PCR. Diagn Microbiol Infect Dis 2003;46:39-47.

108. Corti N, Sennhauser FH, Stauffer UG, Nadal D: Fosfomycin for the initial treatment of acute

haematogenous osteomyelitis. Arch Dis Child 2003;88:512-516. 109. Pabst WL, Altwegg M, Kind C, Mirjanic S, Hardegger D, Nadal D. Prevalence of enteroaggregative

Escherichia coli among children with and without diarrhea in Switzerland. J Clin Microbiol 2003;41:2289-2293.

110. Bonanomi A, Kojic D, Giger B, Rickenbach Z, Jean-Richard-Dit-Bressel L, Berger C, Niggli F, Nadal D.

Quantitative cytokine gene expression in human tonsils at excision and during histoculture assessed by standardized and calibrated real-time PCR and novel data processing. J Immunol Methods 2003;283:27-43.

111. Fischer JE, Seifarth FG, Baenziger O, Fanconi S, Nadal D. Hindsight judgement on ambiguous

episodes of suspected infection in critically ill children: poor consensus amongst experts? Eur J Pediatr 2003;162:840-843.

112. Potocki M, Goette J, Szucs TD, Nadal D. Prospective survey of antibiotic utilization in pediatric

hospitalized patients to identify targets for improvement of prescription. Infection 2003;31:398-403. 113. Audigé A, Schlaepfer E, Bonanomi A, Joller H, Knuchel MC, Weber M, Nadal D, Speck RF. HIV-1 does

not provoke alteration of cytokine gene expression in lymphoid tissue after acute infection ex vivo. J Immunol 2004;172:2687-2696.

114. Glaeser C, Grimm F, Mathis A, Weber R, Nadal D, Deplazes P. Detection and molecular

characterisation of Cryptosporidium spp. isolated from diarrheic children in Switzerland. Pediatr Infect Dis J 2004;23(4):359-361.

115. Berger C, Kindli K, Niggli FK, Nadal D. Withholding initial vancomycin in febrile neutropenia despite

implanted catheters. Eur J Pediatr 2004;163:422-423. 116. Giger B, Bonanomi A,Odermatt B, Ladell K, Speck RF, Kojic D, Berger C, Niggli FK, Nadal D. Human

tonsillar tissue block cultures differ from autologous tonsillar cell suspension cultures in lymphocyte subset activation and cytokine gene expression. J Immunol Methods 2004;289 (1-2):179-190.

117. Battegay M, Berger C, Rochlitz C, Hurwitz N, Hirsch HH, De Geyter C, Haque T, Nadal D. Epstein-Barr

virus load correlating with clinical manifestation and treatment response in a patient with angio-immunoblastic lymphoma. Antiviral Therapy 2004;9:453-459.


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118. Marty A, Marty A, Greiner O, Day PJR, Gunziger S, Mühlemann K, Nadal D. Detection of Haemophilus influenzae type b by Real-Time PCR. J Clin Microbiol 2004;42:3813-3815.

119. Olah E, Berger C, Boltshauser E., Nadal D. Cerebral actinomycosis before adolescence.

Neuropediatrics 2004;35:239-241. 120. Mühlemann K, Franzini C, Aebi C, Berger C, Nadal D, Stähelin J, Gnehm HP, Posfay-Barbe K, Gervaix

A, Heininger U, Bonhoeffer J, Eich G, Kind C, Petignat C, Scalfaro P. Prevalence of nosocomial infection in Swiss pediatric inpatients. Inf Control Hosp Epidemiol 2004;9:765-71.

121. Hengartner H, Berger C, Nadal D, Niggli FK, Grotzer MA. Port-a-cath infections in children with cancer.

Eur J Cancer 2004;40:2452-2458. 122. Duttweiler L, Nadal D, Frey B. Pulmonary and systemic bacterial co-infections in severe RSV

bronchiolitis. Arch Dis Child 2004;89:1155-1157. 123. Horisberger T, Harbarth S, Nadal D, Baenziger O, Fischer JE. G-CSF and IL-8 for early diagnosis of

sepsis in neonates and critically ill children – safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled trial. Crit Care 2004;8:R443-R450.

124. Albisetti M, Lauener RP, Güngör T, Schär G, Niggli FK, Nadal D. Disseminated Fusarium oxysporum

infection in hemophagocytic lymphohistiocytosis. Infection 2004; 32(6):364-366. 125. Bonhoeffer J, Baer G, Muehleisen B, Aebi C, Nadal D, Schaad UB, Heininger U. Prospective

surveillance of hospitalisations associated with varicella-zoster virus infections in children and adolescents. Eur J Pediatr 2005;164:366-370.

126. Gessler P, Pretre R, Bürki C, Rousson V, Frey B, Nadal D. Monocyte function-associated antigen

expression during and after pediatric cardiac surgery. J Thorac Cardiovasc Surg 2005;130:54-60. 127. Huisman TAGM, Boltshauser E, Martin E, Nadal D. Diffusion tensor imaging in progressive multifocal

leukoencephalopathy: Early predictor for demyelination? Am J Neuroradiol 2005;26:2153-2156. 128. Brinkhof MWG, Böni J, Steiner F, Tomasik Z, Nadal D, Schüpbach J, the Swiss HIV Cohort Study

(SHCS), the Swiss HIV Mother + Child Cohort Study (MoCHiV). Evaluation of p24-based antiretroviral treatment monitoring in pediatric HIV-1 infection: prediction of the CD4+ T-cell changes between consecutive visits. J Acquir Immune Defic Syndr 2006,41:557-562.

129. Bernasconi M, Berger C, Sigrist JA, Bonanomi A, Sobek J, Niggli FK, Nadal D. Quantitative profiling of

housekeeping and Epstein-Barr virus gene transcription in Burkitt lymphoma cell lines using an oligonucleotide microarray. Virology J 2006;3:43.

130. Schüpbach J, Tomasik Z, Knuchel M, Opravil M, Günthard HF, Nadal D, Böni J, the Swiss HIV Cohort

Study (SHCS), the Swiss HIV Mother + Child Cohort Study (MoCHiV). Optimized virus disruption improves detection of HIV-1 p24 in particles and uncovers a p24 reactivity in patients with undetectable HIV-1 RNA under long-term HAART. J Med Virol 2006;78:1003-1010.

131. Zucol F, Ammann RA, Berger C, Aebi C, Altwegg M, Niggli FK, Nadal D. Real-time quantitative broad-

range PCR assay for detection of the 16S rRNA gene followed by sequencing for species identification. J Clin Microbiol 2006;44:2750-2759.

132. Rao SP, Rechsteiner MP, Berger C, Sigrist JA, Nadal D*, Bernasconi M*. Zebularine reactivates

silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt’s lymphoma Akata cells. Mol Cancer 2007;6:3. *equal contribution

133. Knuchel MC, Jullu B, Sha C, Tomasik Z, Stoeckle MP, Speck RF, Nadal D, Mshinda H, Böni J, Tanner

M, Schüpbach J. Adaptation of the ultrasensitive HIV-1 p24 antigen assay to dried blood spot testing. J Acquir Immune Defic Syndr 2007;44:247-253.


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134. Ishii H, Ogino T, Berger C, Köchli-Schmitz N, Nagato T, Takahara M, Nadal D, Harabuchi Y. Clinical usefulness of serum EBV DNA levels of BamHIW and LMP1 for nasal NK/T-cell lymphoma. J Med Virol 2007;79:562-572.

135. Rechsteiner MP, Berger C, Weber M, Sigrist JA, Nadal D*, Bernasconi M*. Silencing of latent

membrane protein 2B (LMP2B) reduces susceptibility to activation of lytic Epstein-Barr virus in Burkitt's lymphoma Akata cells. J Gen Virol 2007;88:1454-1459. *equal contribution

136. Ammann R, Zucol F, Aebi C, Niggli F, Kühne T, Nadal D. Real-time broad-range PCR versus blood

culture. A prospective pilot study in pediatric cancer patients with fever and neutropenia. Support Care Cancer 2007;15:637-641.

137. Berger C, Hug M, Gysin C, Molinari L, Frei M, Bossart W, Nadal D. Distribution patterns of β- and γ-

Herpesviruses within Waldeyer's ring organs. J Med Virol, 2007;79:1147-1152. 138. Ladell K, Dorner M, Zauner L, Berger C, Zucol F, Bernasconi M, Niggli F, Speck R, Nadal D. Immune

activation suppresses initiation of lytic Epstein-Barr virus infection. Cell Microbiol 2007;9:2055-2069. 139. Rechsteiner MP, Berger C, Zauner L, Sigrist JA, Weber M, Longnecker R, Bernasconi M, Nadal D.

Latent membrane protein 2B regulates susceptibility to induction of lytic Epstein-Barr virus infection. J Virol 2008;82:1739-1747.

140. Dorner M, Zucol F, Berger C, Byland R, Melroe GT, Bernasconi M, Speck RF, Nadal D. Distinct ex vivo

susceptibility of B-cell subsets to Epstein-Barr virus infection according to differentiation status and tissue origin. J Virol 2008;82:4400-4412.

141. Rudin C, Burri M, Shen Y, Rode R, Nadal D. Long-term safety and effectiveness of Ritonavir, Nelfinavir

and Lopinavir/Ritonavir in antiretroviral-experienced HIV-infected children. Pediatr Infect Dis J 2008;27:1-7.

142. De Beaucoudrey L, Puel A, Filipe-Santos O, Cobat A, Ghandil P, Chrabieh M, Feinberg J, von Bernuth

H, Samarina A, Jannière L, Fieschi C, Stéphan JL, Boileau C, Lyonnet S, Jondeau G, Cormier-Daire V, Le Merrer M, Hoarau C, Lebranchu Y, Lortholary O, Chandesris MO, Tron F, Gambineri E, Bianchi L, Rodriguez-Gallego C, Zitnik SE, Vasconcelos J, Guedes M, Vitor AB, Marodi L, Chapel H, Reid B, Roifman C, Nadal D, Reichenbach J, Caragol I, Garty BZ, Dogu F, Camcioglu Y, Gülle S, Sanal O, Fischer A, Abel L, Stockinger B, Picard C, Casanova JL. Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells. J Exp Med 2008;205:1543-1550.

143. Wiegering VA, Kellenberger CJ, Bodmer N, Bergstraesser E, Niggli F, Grotzer M, Nadal D, Bourquin J-

P. Conservative management of acute appendicitis in children with hematologic malignancies during chemotherapy-induced neutropenia. J Pediatr Hematol Oncol 2008;30:464-467.

144. Neuhaus TJ, Berger C, Buechner K, Parvex P, Bischoff G, Goetschel P, Husarik D, Willi U, Molinari L,

Rudin C, Gervaix A, Hunziker U, Stocker S, Girardin E, Nadal D. Randomised trial of oral versus sequential intravenous/oral cephalosporins in children with pyelonephritis. Eur J Pediatr 2008;167:1037-1047.

145. Weber R, Berger C, Balmer C, Kretschmar O, Bauersfeld U, Pretre R, Nadal D*, Knirsch W*.

Interventions using foreign material to treat congenital heart disease in children increase the risk for infective endocarditis. Pediatr Infect Dis J 2008;27:544-550. *equal contribution

146. Bihl F, Berger C, Chisholm JV, Henry LM, Bertisch B, Trojan A, Nadal D, Speck RF, Flepp M, Brander

C, Mueller NJ, and the Swiss HIV Cohort Study. Cellular immune responses and disease control in acute AIDS-associated Kaposi's sarcoma. AIDS 2009;23:1918-1922.

147. Dorner M, Brandt S, Tinguely M, Zucol F, Bourquin JP, Zauner L, Berger C, Bernasconi M, Speck RF,

Nadal D. Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production. Immunology 2009;128:573-579.


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148. Myers C, Posfay-Barbe KM, Aebi C, Cheseaux JJ, Kind C, Rudin C, Nadal D, Siegrist CA, the Pediatric Infectious Disease Group of Switzerland (PIGS), and the Swiss Mother & Child HIV Cohort Study (MoCHIV). Determinants of vaccine immunity in the cohort of Human Immunodeficiency Virus-infected children living in Switzerland. Pediatr Infect Dis J 2009;28:996-1001.

149. Gibb DM, Castro H, Compagnucci A, Klein N, Lallemant M, Lyall H, Nadal D, Ananworanich J, Babiker

A, Bunupuradah T, Darbyshire JH, De Rossi A, Gonzalez Tomé MI, Harper L, Kanjavanit S, Marczynska M, Mofenson L, Monpoux F, Moye J, Muñoz-Fernández MA, Ngo-Giang-Huong N, Niehues T, Saidi Y, Walker AS, Wintergerst U, Giaquinto C for PENTA. Response to planned treatment interruptions in HIV infection varies across childhood. AIDS 2010;24:231-241.

150. Schlagenhauf P, Chen LH, Wilson ME, Freedman DO, Tcheng D, Schwartz E, Pandey P, Weber R,

Nadal D, Berger C, von Sonnenburg F, Keystone J, Leder K, for the GeoSentinel Surveillance Network Clinical Infectious Diseases. Sex and gender differences in travel-associated disease. Clin Infect Dis 2010;50:826-832.

151. Rudin C, Wolbers M, Nadal D, Rickenbach M, Bucher HC; the Pediatric Infectious Disease Group of

Switzerland (PIGS) and the Swiss Mother and Child HIV Cohort Study (MoCHiV). Long-term safety and effectiveness of lopinavir/ritonavir in antiretroviral-experienced HIV-1-infected children. Arch Dis Child 2010;95:478-481.

152. Hofer U, Schlaepfer E, Baenziger S, Nischang M, Regenass S, Schwendener R, Kempf W, Nadal D,

Speck RF. Inadequate clearance of translocated bacterial products in HIV-infected humanized mice. PLoS Pathog 2010;6:1-10.

153. Dorner M, Zucol F, Alessi D, Haerle SK, Bossart W, Weber M, Byland R, Bernasconi M, Berger C,

Tugizov S, Speck RF, Nadal D. β1 Integrin expression increases susceptibility of memory B-cells to Epstein-Barr virus infection. J Virol 2010;84:6667-6677.

154. Ammann RA, Bodmer N, Hirt A, Niggli FK, Nadal D, Simon A, Ozsahin H, Kontny U, Kühne T, Beck

Popovic M, Ridolfi Lüthy A, Aebi C. Predicting adverse events in children with fever and chemotherapy-induced neutropenia: The prospective multicenter SPOG 2003 FN study. J Clin Oncol 2010;28:2008-2014.

155. Zauner L, Melroe GT, Sigrist JA, Rechsteiner MP, Dorner M, Arnold M, Berger C, Bernasconi M,

Schaefer BW, Speck RF, Nadal D. TLR9 triggering in Burkitt's lymphoma cell lines suppresses the EBV BZLF1 transcription via histone modification. Oncogene 2010;29:4588-4598.

156. Hug M, Dorner M, Zucol Fröhlich F, Gysin C, Neuhaus D, Nadal D*, Berger C*. Pediatric Epstein-Barr

virus carriers with or without tonsillar enlargement may substantially contribute to spreading of the virus. J Infect Dis 2010;202:1192-1199. *equal contribution

157. Audigé A, Taffé P, Rickenbach M, Battegay M, Vernazza P, Nadal D, Speck RF and the Swiss HIV

Cohort Study (SHCS). Low postseroconversion CD4 count and rapid decrease of CD4 density identify HIV+ fast progressors. AIDS Res Hum Retroviruses 2010; 26:997-1005.

158. Audigé A, Schlaepfer E, von Wyl V, Miller RC, Vernazza P, Nadal D, Speck RF and the SHCS. B-cells

from HIV-infected patients with primary central nervous system lymphoma display an activated phenotype and have blunted TNF-α response to TLR9 triggering. AIDS Res Hum Retroviruses 2010;26:1063-1074.

159. De Beaucoudrey L, Samarina A, Bustamante J, Cobat A, Boisson-Dupuis S, Feinberg J, Al-Muhsen S,

Jannière L, Rose Y, de Suremain M, Kong XF, Filipe-Santos O, Chapgier A, Picard C, Fischer A, Dogu F, Ikinciogullari A, Tanir G, Al-Hajjar S, Al-Jumaah S, Frayha HH, AlSum Z, Al-Ajaji S, Alangari A, Al-Ghonaium A, Adimi P, Mansouri D, Ben-Mustapha I, Yancoski J, Garty BZ, Rodriguez-Gallego C, Caragol I, Kutukculer N, Kumararatne DS, Patel S, Doffinger R, Exley A, Jeppsson O, Reichenbach J, Nadal D, Boyko Y, Pietrucha B, Anderson S, Levin M, Schandené L, Schepers K, Efira A, Mascart F, Matsuoka M, Sakai T, Siegrist CA, Frecerova K, Blüetters-Sawatzki R, Bernhöft J, Freihorst J, Baumann U, Richter D, Haerynck F, De Baets F, Novelli V, Lammas D, Vermylen C, Tuerlinckx D, Nieuwhof C, Pac M, Haas WH, Müller-Fleckenstein I, Fleckenstein B, Levy J, Raj R, Cohen AC, Lewis


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DB, Holland SM, Yang KD, Wang X, Wang X, Jiang L, Yang X, Zhu C, Xie Y, Lee PP, Chan KW, Chen TX, Castro G, Natera I, Codoceo A, King A, Bezrodnik L, Di Giovani D, Gaillard MI, de Moraes-Vasconcelos D, Grumach AS, da Silva Duarte AJ, Aldana R, Espinosa-Rosales FJ, Bejaoui M, Bousfiha AA, Baghdadi JE, Ozbek N, Aksu G, Keser M, Somer A, Hatipoglu N, Aydogmus C, Asilsoy S, Camcioglu Y, Gülle S, Ozgur TT, Ozen M, Oleastro M, Bernasconi A, Mamishi S, Parvaneh N, Rosenzweig S, Barbouche R, Pedraza S, Lau YL, Ehlayel MS, Fieschi C, Abel L, Sanal O, Casanova JL. Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine 2010;89:381-402.

160. Santy K, Nan P, Chantana Y, Laurent D, Nadal D, Richner B. The diagnosis of brain tuberculoma by

1H-magnetic resonance spectroscopy. Eur J Pediatr 2011;170:379-387. 161. Miller RC, Schlaepfer E, Baenziger S, Crameri R, Zeller S, Byland R, Audigé A, Nadal D, Speck RF.

HIV interferes with SOCS-1 and -3 expression levels driving immune activation. Eur J Immunol 2011; 41:1058-1069.

162. Agyeman P, Aebi C, Hirt A, Niggli FK, Nadal D, Simon A, Ozsahin H, Kontny U, Kühne T, Beck Popovic

M, Leibundgut K, Bodmer N, Ammann RA. Predicting bacteremia in children with cancer and fever in chemotherapy-induced neutropenia. Results of the prospective multicenter SPOG 2003 FN study. Pediatr Infect Dis J;2011;30:e114-e119.

163. L'Huillier AG, Ferry T, Courvoisier DS, Aebi C, Cheseaux JJ, Kind C, Rudin C, Nadal D, Hirschel B,

Sottas C, Siegrist CA, Posfay-Barbe KM, the Pediatric Infectious Diseases Group of Switzerland (PIGS), the Swiss HIV Cohort Study (SHCS) and the Swiss Mother & Child HIV Cohort Study (MoCHiV). Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity. HIV Med 2012;13:54-61.

164. Hunziker T, Berger C, Staubli G, Tschopp A, Weber R, Nadal D, Hatz C, Schlagenhauf P. Profile of

travel-associated illness in children, Zurich, Switzerland. J Travel Med 2012;19:158-162. 165. Lüthi F, Leibundgut K, Niggli FK, Nadal D, Aebi C, Bodmer N, Ammann RA. Serious medical

complications in children with cancer and fever in chemotherapy-induced neutropenia: results of the prospective multicenter SPOG 2003 FN study. Pediatr Blood Cancer 2012;59;90-95.

166. Noack J, Jordi M, Zauner L, Alessi D, Burch A, Tinguely M, Hersberger M, Bernasconi M*, Nadal D*.

TLR9 agonists induced cell death in Burkitt's lymphoma cells is variable and influenced by TLR9 polymorphism. Cell Death Dis 2012;3:e323. *equal contribution

167. Santy K, Nan P, Chantana Y, Laurent D, Scheer I, Steinmann B, Nadal D, Richner B. Non-invasive

diagnosis of lung tuberculosis in children by single voxel 1H-magnetic resonance spectroscopy. Eur J Pediatr 2012;171:1257-1263.

168. Crisinel PA, Posfay-Barbe KM, Aebi C, Cheseaux JJ, Kahlert C, Rudin C, Nadal D, Siegrist CA.

Determinants of hepatitis A vaccine immunity in a cohort of human immunodeficiency virus-infected children living in Switzerland. Clin Vaccine Immunol 2012;19:1751-1757.

169. Bansal V, Altermatt S, Nadal D, Berger C. Lack of benefit of preoperative antimicrobial prophylaxis in

children with acute appendicitis: a prospective cohort study. Infection 2012;40:635-641. 170. Bernasconi M, Ueda S, Krukowski P, Bornhauser BC, Ladell K, Dorner M, Sigrist JA, Campidelli C,

Aslandogmus R, Alessi D, Berger C, Pileri SA, Speck RF, Nadal D. Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases. Int J Cancer 2013;133:2341-2350.

171. Lünemann A, Vanoaica LD, Azzi T, Nadal D, Münch C. A distinct subpopulation of human NK cells

restricts B cell transformation by EBV. J. Immunol 2013;191:4989-4995. 172. Ueda S, Uchiyama S, Azzi T, Gysin C, Berger C, Bernasconi M, Harabuchi Y, Zinkernagel AS, Nadal D.

Oropharyngeal Group A Sreptococcal colonization disrupts latent Epstein-Barr virus infection. J Infect Dis 2014;209:255-264.


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173. Meyer Sauteur PM, Relly C, Hackenberg A, Stahr N, Berger C, Bloemberg GV, Jacobs E, Nadal D.

Mycoplasma pneumoniae intrathecal antibody responses in Bickerstaff brainstem encephalitis. Neuropediatrics 2013; June 21 [Epub ahead of print]

174. Steppacher A, Scheer I, Relly C, Zacek B, Turk A, Altpeter E, Berger C, Nadal D. Unrecognized

pediatric adult-type tuberculosis puts school contacts at risk. Pediatr Infect Dis J 2013; Oct 28 [Epub ahead of print]

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13. Lorenzi P, Masserey Spicher V, Laubereau B, Hirschel B, Kind C, Rudin C, Irion O, Kaiser L, the Swiss

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14. Venetz I, Schopfer K, Mühlemann K, Swiss Pneumococcal Study Group. Paediatric, invasive

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17. Kern WV, Cometta A, de Bock R, Langenaeken J, Paesmans M, Gaya H for the International

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38. Keiser O, Orrell C, Egger M, Wood R, Brinkhof MW, Furrer H, van Cutsem G, Ledergerber B, Boulle A,

the Swiss HIV Cohort Study, the International Epidemiologic Databases to Evaluate AIDS in Southern Africa. Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared. PLoS Med 2008;5:e148.

39. Brossard P, Boulvain M, Coll O, Barlow P, Aebi-Popp K, Bischof P, Martinez de Tejada B, the Swiss

HIV Cohort Study, the Swiss Mother and Child HIV Cohort Study. Is screening for fetal anomalies reliable in HIV-infected pregnant women? A multicenter study. AIDS 2008;22:2013-2017.

40. Keiser O, Gayet-Ageron A, Rudin C, Brinkhof MW, Gremlich E, Wunder D, Drack G, Hirschel B,

Martinez de Tejada B, the Swiss HIV Cohort Study, the Swiss Mother and Child HIV Cohort Study. Antiretroviral treatment during pregnancy. AIDS 2008;22:2323-2330.

41. Jacqz-Aigrain E, Harrison L, Zhao W, Compagnucci A, Castro (née Green) H, Farrelly L, Saidi Y,

Hamadache D, Welch S, Wintergerst U, Forcat S, Hadjou G, Firtion G, Snowden W, Giaquinto C, Gibb DM, Burger D for the Paediatric European Network for Treatment of AIDS. Pharmacokinetic study of once-daily versus twice-daily abacavir and lamivudine in HIV type-1-infected children aged 3-<36 months. Antivir Ther 2010;15:297-305.


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c) Reviews 1. Lüdin CE, Nadal D, Gnehm HpE. Lyme-Krankheit (Erythema-migrans-Krankheit). Ther Umschau

1986;43:537-539. 2. Baerlocher K, Nadal D. Das Menkes-Syndrom. Ergeb Inn Med Kinderhkd 1988;57:79-144. 3. Hirsig J, Schwöbel M, Nadal D. Bedeutung pathophysiologischer Grundlagen der intestinalen Sekretion

für Diagnose und Therapie des Ileus. Z Kinderchir 1988;43:319-321. 4. Nadal D, Ogra PL. Development of local immunity: role in mechanisms of protection against or

pathogenesis of respiratory syncytial viral infections. Lung 1990;168:S379-S387. 5. Herrmann P, Nadal D, Baumann A, Fanconi A. Akute Mastoiditis: Erfahrungen an 73 Kindern. In:

Aktuelle Probleme der Otorhinolaryngologie. ORL 13. Hrsg. B Kellerhals, U Fisch, J Mann, D de Montmollin, J-P de Reynier. Hans Huber, Bern, 1990, pp 32-38.

6. Frei K, Nadal D, Fontana A. Intracerebral synthesis of tumor necrosis factor-α and interleukin-6 in

infectious meningitis. Ann NY Acad Sci 1990;594:326-335. 7. Bernasconi E, Nadal D, Vogt M. Verdacht auf Lyme-Borreliose: wie abklären, wen behandeln? Ther

Umschau 1992;49:257-262. 8. Nadal D, Ogra PL. The middle ear: an immunoreactive organ. In: Immunobiology in Otology, Rhinology

and Laryngology. Proceedings of the Third International Academic Conference on Immunobiology in Otology, Rhinology and Laryngology, Coronado, CA, USA, November 8-10, 1990. Eds. B.F. McCabe, J.E. Veldman and G. Mogi. Kugler Publications, Amsterdam/New York 1992, pp 123-128.

9. Nadal D, Ogra PL. Vaccination approaches for infections of the respiratory tract. In: Lim DJ, Bluestone

CD, Klein JO, Nelson JD, Ogra PL (eds). Recent Advances in Otitis Media with Effusion. Proceedings of the Fifth International Symposium. Toronto: BC Decker 1993, pp 222-229.

10. Bernstein JM, Nadal D, Faden HF. Longitudinal characteristics of isotypic specificity of serum

bactericidal antibody against nontypable Haemophilus influenzae (NTHI). In: Lim DJ, Bluestone CD, Klein JO, Nelson JD, Ogra PL (eds). Recent Advances in Otitis Media with Effusion. Proceedings of the Fifth International Symposium. Toronto: BC Decker 1993, pp 184-187.

11. Nadal D, Vogt M. Klinik und Therapie der Infektionen mit Herpes-simplex- und Varicella-zoster-Virus in

der Praxis. Ther Umschau 1994;51:538-544. 12. Vaudaux B, Rudin Ch, Kind C, Schaad UB, Gnehm H.E, Nadal D, Suter S, Calame A, Hohlfeld P.

Toxoplasmose congénitale: prise en charge pédiatrique. Schweiz Med Wochenschr 1995;125 (Suppl. 65):70S-81S.

13. Albini B, Nadal D, Chen C, Schlapfer E, Mookerjee BK, Stulnig T, Ogra PL, Wick G, Cohen SA.

Assessment of engraftment and function of human tonsillar and blood mononuclear cells in immunodeficient mice. Adv Exp Med Biol 1995;371 A:85-89.

14. Zedler C, Zedler-Spéhler D, Nadal D, van Waes H. Mundschleimhaut-Veränderungen bei Kindern.

Schweiz Monatsschr Zahnmed 1996;106:15-24. 15. Nadal D. Epstein-Barr-Virus in Tumorzellen: Blinder Passagier oder Steuermann? Vierteljahrsschrift

Naturforsch Ges ZH 1996;141/2:45-52. 16. Exhenry C, Nadal D. Vertical human immunodeficiency virus-1 infection: involvement of the central

nervous system and treatment. Eur J Pediatr 1996;155:839-850. 17. Nadal D, Zbinden R. Erkrankungen durch Bartonellen. Internist 1996;37:890-894.


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18. Linder T, Funke G, Schmid S, Nadal D. Die akute Otitis media und der Tubenmittelohrkatarrh: ein Ueberblick über die Pathogenese und Empfehlungen zur Therapie. Schweiz Med Wochenschr 1996;126:2223-2233.

19. Albisetti M, Nadal D. L’importance de la sérologie pour le diagnostic de la maladie des griffes de chat et

des autres bartonelloses. Méd et Hyg 1997;55:311-313. 20. Nadal D. Bekanntes und Neues zur Epstein-Barr-Virus-Infektion. Ther Umschau 1998;55:52-56. 21. Nadal D. Bahnen Viren und Bakterien einander den Weg für Infektionen? Labor und Medizin

1998;25:244-247. 22. Nadal D. Lungenerkrankungen bei HIV-infizierten Kindern. Schweiz Med Wochenschr

1998;128:1375-1384. 23. Nadal D. HIV-Infektion beim Kind: Beginnt der Horizont sich klarer abzuzeichnen? Schweiz Med

Wochenschr 1999;129:30-33. 24. Nadal D, Weber R. Diagnose und Therapie der akuten Tonsillopharyngitis durch Gruppe A β-

hämolysierende Streptokokken. Schweiz Ärzteztg 1999;80:599-601. 25. Schupbach J, Tomasik Z, Boni J, Nadal D, Flepp M, Ledergerber B, Opravil M, Cone R. Use of HIV-1

p24 as a sensitive, precise and inexpensive marker for infection, disease progression and treatment failure. The Fourth European Conference on Experimental AIDS Research 1999;157-162.

26. Aebi C, Nadal D, Kind C, Pfister R, Barazzone C, Hammer J. Konsensus Statement zur Prävention von

Respiratory Syncytial Virus (RSV)-Infektionen beim Neugeborenen und Säugling mit dem humanisierten monoklonalen Antikörper Palivizumab (SynagisTM). Schweiz Ärzteztg 1999;80:2927-2930.

27. Nadal D. Impfungen. Ther Umschau 1999;56:698-707. 28. Nadal D. Fortschritte im Verständnis der Pathogenese und der Prävention von bakterieller Otitis media

und Meningitis. Schweiz Med Wochenschr 1999;129:2017-2020. 29. Nadal D. Is the in-vitro interferon-γ release assay an adequate replacement for the tuberculin skin test?

Clin Infect Dis 2002;34:1457-1459. 30. Aebi C, Barazzone C, Hammer J, Kind C, Nadal D, Pfister RE. Update zum Konsensus-Statement zur

Prävention von Respiratory Syncytial Virus (RSV)-Infektionen bei Säuglingen mit dem humanisierten monoklonalen Antikörper Palivizumab (Synagis®). Paediatrica 2002;13:58-62.

31. Aebi C, Barazzone C, Günthardt J, Hammer J, Kind C, Nadal D, Pfammatter JP, Pfister RE. Konsensus

Statement zur Prävention von Respiratory Syncytial Virus (RSV)-Infektionen mit dem humanisierten monoklonalen Antikörper Palivizumab (Synagis®). Paediatrica 2004;15(6):12-16.

32. Aebi C, Barazzone C, Günthardt J, Hammer J, Kind C, Nadal D, Pfammatter JP, Pfister RE. Consensus

concernant la prévention des infections par le virus respiratoire syncitial (VRS) avec l’anticorps humanisé monoclonal palivizumab (Synagis®). Paediatrica 2004;15(6):17-19.

33. Kahlert Ch, Nadal D. Akutes Fieber beim Kleinkind. Ther Umschau 2006;63:659-665. 34. Kempf W, Meylan P, Gerber S, Aebi C, Agosti R, Büchner S, Coradi B, Garweg J, Hirsch HH, Kind C,

Lauper U, Lautenschlager S, Reusser P, Ruef C, Wunderli W, Nadal D for the Swiss Herpes Management Forum. Swiss recommendations for the management of varicella zoster virus infections. Swiss Med Wkly 2007;137:239-251.

35. Kahlert C, Nadal D. Toxische Schocksyndrome. Infektionen mit Toxin bildenden Staphylokokken und

Streptokokken im Kindesalter. Pädiat Prax 2008;71:613-619.


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36. Rechsteiner MP, Bernasconi M, Berger C, Nadal D. Role of latent membrane protein 2 isoforms in Epstein-Barr virus latency. Trends Microbiol 2008;16:520-527.

37. Knirsch W, Nadal D. Infective endocarditis in congenital heart disease. Eur J Pediatr 2011;170:1111-

1127. 38. Zauner L, Nadal D. Understanding TLR9 action in Epstein-Barr virus infection. Front Biosci

2012;17:1219-1231. 39. Berger C, Boggian K, Cusini A, van Delden C, Garzoni C, Hirsch HH, Khanna N, Koller M, Oriol M,

Meylan P, Nadal D, Weisser M, Mueller NJ, Transplant Infectious Diseases Working Group, Swiss Transplant Cohort Study. Relevance of cohort studies for the study of transplant infectious diseases. Curr Opin Organ Transplant 2012;17:581-585.

40. Liese J, Abele-Horn M, Beer M, Forster J Heininger U, Nadal D, Rose M, Scholz H. Diagnose und

Behandlung der Pneumonie im Kindesalter. Monatsschr Kinderheilkd 2013;161:703-712. 41. Chijioke O, Azzi T, Nadal D, Münz C. Innate immune responses against Epstein Barr virus infection. J

Leukoc Biol 2013;94:1185-1190. 42. Karrer U, Nadal D. Epstein-Barr Virus und infektiöse Mononukleose. Schweiz Medizin-Forum 2013; in

press d) Book Chapters 1. Baerlocher K, Nadal D. Metabolische Parameter nach Gabe verschiedener Kohlenhydrate - Qualitative

und quantitative Aspekte. In: Bedeutung hochmolekularer Kohlenhydrate in der Säuglings- und Kinderernährung (Eds. Baerlocher K, Wachtel U) Georg Thieme Verlag, Stuttgart New York, 1984, pp 46-75.

2. Nadal D. Chlamydieninfektionen. In Immunologie und Infektionskrankheiten. Fortbildung in der

Kinderheilkunde (Eds. Olbing H und Palitzsch D). Hansisches Verlagskontor, Lübeck, 1987, pp 115-123.

3. Nadal D, Joller P, Hitzig WH. Durch Infektion mit human immunodeficiency virus (HIV) erworbene

Immunschwäche (AIDS) im Kindesalter. In: Bachmann K-D, et al. (Eds.) Pädiatrie in Praxis und Klinik Georg Thieme 1989, pp 541-555.

4. Fontana A, Frei K, Gallo P, Leist TP, Leppert D, Malipiero UV, Nadal D. Immunoregulation in the central

nervous system: detection of cytokines in cerebrospinal fluid. In Marrosu MG, Cianchetti C, Tavolato B (Eds.): Trends in Neuroimmunology. Plenum Press, New York, 1990, pp 77-86.

5. Nadal D, Schläpfer E, Ogra PL. Homing characteristics of mucosal lymphoid tissue and functional

aspects of cellular mucosal immunity to respiratory syncytial virus. In Tsuchiya M, Nagura H, Hibi T, Moro I (Eds.): Frontiers of Mucosal Immunology. Elsevier, Amsterdam, 1991, pp 133-137.

6. Frei K, Nadal D, Ralph P, Fontana A. Cytokines in inflammatory brain diseases. In Cellular and cytokine

networks in tissue immunity. Wiley-Liss, Chichester, 1991, pp 91-98. 7. Nadal D, Ogra PL. Tonsils: the gatekeeper of mucosal immunity? In Advances in Oto-Rhino-

Laryngology, Vol. 47. Tonsils: An Update, Karger, Basel, 1992, pp 76-79. 8. Nadal D. Skelettinfektionen. In Pädiatrische Infektiologie. Editor Schaad UB. Hans Marseille Verlag

GmbH München, 1993, pp 409-424. 9. Nadal D, Braegger CP, Knoflach P, Albini, B. Malabsorption syndromes. In Mucosal Immunology: Part

II: Mucosal Diseases. Eds. Ogra PL, Mestecky J, Lamm M, Strober W, McGhee J, Bienenstock J. Academic Press, New York, 1994, pp 457-491.


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10. Bernstein JM, Yamanaka N, Nadal D. Immunobiology of the tonsils and adenoids. In Mucosal Immunology: Part II: Mucosal Diseases. Eds. Ogra PL, Mestecky J, Lamm M, Strober W, McGhee J, Bienenstock J. Academic Press, New York, 1994, pp 625-640.

11. Nadal D. Virusinduzierte Immundysfunktion (ausgenommen HIV). In Pädiatrische Allergologie und

Immunologie, 3. Auflage. Eds. Wahn U, Seger R, Wahn V, Holländer GA. Urban und Fischer Verlag, München, 1999, pp 542-551 and 4th Edition 2005, pp 699-709.

12. Berger C, Nadal D. Bakteriologische Diagnostik In Pädiatrische Pneumologie. Eds. Rieger C, von der

Hardt H, Sennhauser FH, Wahn U, Zach M. Springer Verlag Berlin, 1999, pp 259-266 and 2nd Edition 2004, pp 240-247.

13. Ziegler S, Nadal D. Antibakterielle Therapie. In Pädiatrische Pneumologie. Eds. Rieger C, von der

Hardt H, Sennhauser FH, Wahn U, Zach M. Springer Verlag Berlin, 1999, pp 321-339 and 2nd Edition 2004, pp 300-318.

14. Nadal D. Infekte der oberen Atemwege. In Pädiatrische Pneumologie. Eds. Rieger C, von der Hardt H,

Sennhauser FH, Wahn U, Zach M. Springer Verlag Berlin, 1999, pp 679-706 and 2nd Edition 2004, pp 630-656.

15. Nadal D, Berger C. Bakterielle Infektionen. In Lehrbuch Pädiatrie. Eds. Speer CP, Gahr M. Springer

Verlag Heidelberg, 2000, pp 411-468, 2nd Edition 2004, pp 471-524, 3rd Edition 2009, pp 383-426, and 4th Edition 2013, pp 371-412.

16. Nadal D. Einsatz von Immunglobulinen bei anderen Infektionen. In Klinischer Einsatz von intravenösen

Immunglobulinen. Editor Wahn V. UNI-MED Verlag Bremen 2000, pp 51-54; 2nd Edition 2003, pp 63-66; and 4th Edition 2007, pp. 68-74.

17. Nadal D. Sekundäre Immundefekte (ausgenommen HIV). In Pädiatrie Grundlagen und Praxis. Eds.

Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 566-568; 2nd Edition 2003, pp 609-611; and 3rd Edition 2007, pp 642-645.

18. Zepp F, Nadal D. Erhöhte Infektanfälligkeit. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ,

Schaub J, Schulte FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 574; 2nd Edition 2003, pp 617-618; and 3rd Edition 2007, pp 651-652.

19. Nadal D. Katzenkratzkrankheit. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ, Schaub J, Schulte

FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 713-715; 2nd Edition 2003, pp 770-771; and 3rd Edition 2007, pp 800-801.

20. Nadal D. Rickettsiosen. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ, Schaub J, Schulte FJ,

Spranger J. Springer Verlag Heidelberg, 2001, pp 716-717; 2nd Edition 2003, pp 772-774; and 3rd Edition 2007, pp 802-804.

21. Nadal D. Virale hämorrhagische Fieber. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ, Schaub

J, Schulte FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 742-746; 2nd Edition 2003, pp 799-804; and 3rd Edition 2007, pp 830-834.

22. Nadal D, Schulte FJ. Bakterielle Infektionen. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ,

Schaub J, Schulte FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 1354-1360; 2nd Edition 2003, pp 1430-1437; and 3rd Edition 2007, pp 1487-1492.

23. Nadal D, Schulte FJ. Virusinfektionen. In Pädiatrie Grundlagen und Praxis. Eds. Lentze MJ, Schaub J,

Schulte FJ, Spranger J. Springer Verlag Heidelberg, 2001, pp 1360-1366; 2nd Edition 2003, pp 1437-1442; and 3rd Edition 2007, pp 1494-1499.

24. Nadal D, Berger C. Bakterielle Infektionen beim Kind. ComMed Verlagsagentur Basel, 2003, pp 1-168. 25. Weiss M, Handrick W, Borte M, Nadal D, Spencker F-B, Stojanov S. Fieber unklarer Genese. In

Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und


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Jugendlichen, 4th Edition, Futuramed Verlag München 2003, pp 168-180; and 5th Edition, Thieme Verlag, Stuttgart 2009, pp 130-135.

26. Heininger U, Abele-Horn M, Jacobs E, Nadal D. Mykoplasmen-Infektionen. In Deutsche Gesellschaft

für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen, 4th Edition, Futuramed Verlag, München 2003, pp 523-526; 5th Edition, Thieme Verlag Stuttgart 2009, pp 388-389; and Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. 6th Edition 2013, pp 410-412.

27. Nadal D, Schroten H. Nocardiosen. In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI)

Handbuch: Infektionen bei Kindern und Jugendlichen, 4th Edition, Futuramed Verlag, München 2003, pp 527-530; 5th Edition, Thieme Verlag Stuttgart, 2009, pp 390-392; and Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. 6th Edition 2013, pp 413-415.

28. Scholz H, Ahrens P, Belohradsky BH, Heininger U, Liese J, Luckhaupt H, Nadal D, Nicolai T, Riedel F,

Rieger C. Atemwegsinfektionen. In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen, 4th Edition, Futuramed Verlag München, 2003, pp 751-781; and 5th Edition, Thieme Verlag Stuttgart, 2009, pp 570-591.

29. Nadal D, Greiner O, Berger C, Day PJR, Tang CM. Detection of Neisseria meningitidis in tonsils varies

in relation to the frequency of invasive disease. In: Current Topics on Tonsils and Mucosal Barriers of Upper Airways. International Congress Series 1257. Eds. Yamanaka N, Kuki K, Tamura S, Hotomi M. ElsevierAmsterdam, 2003, pp 133-140.

30. Nadal D. Pediatric infectious diseases –Quo vadis 2015? In Pediatric Infectious Diseases Revisited.

Eds. Schroten H, Wirth S. Birkhäuser Verlag Basel, 2007, pp 485-496. 31. Nadal D. Application of immunoglobulins in other infections. In Clinical use of immunoglobulins. Eds.

Wahn V, Orange J. UNI-MED Verlag Bremen, 2008, pp 72-78. 32. Nadal D, Dehio C, Kempf V. Kapitel Bartonellosen. In Deutsche Gesellschaft für Pädiatrische

Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen, 5th Edition, Thieme Verlag Stuttgart, 2009, pp 162-164; and Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. 6th Edition 2013, pp 166-168.

33. Beetz R, Berner R, Kuwertz-Bröking E, Nadal D, Roos R, Rösch W, Wagenlehner F, Weber L. Kapitel

Harnwegsinfektionen. In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen, 5th Edition, Thieme Verlag Stuttgart, 2009, pp 622-635; and Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. 6th Edition 2013, pp 688-700.

34. Barben J, Berger C, Bodmer T, Egger JM, Merlani G, Helbling P, Janssens JP, Nadal D, Nicod L, Turk

A, Vukmirovic B, Zellweger JP, Zimmerli S. Handbuch Tuberkulose. Lungenliga Schweiz, Bundesamt für Gesundheit 2011; pp 1-88.

35. Niehues T, Borte M, Dueckers G, Nadal D, Schulze I. Kapitel Passive Immuntherapie und –prophylaxe.

In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 44-47.

36. Nadal D, Schuster V. Kapitel Virostatika. In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI)

Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 109-114.

37. Schuster V, Korn K, Nadal D, Wagner H-J. Kapitel Epstein-Barr-Virus-Infektionen. In Deutsche

Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 249-251.

38. Schuster V, Nadal D, Roos R, Sauerbrei A. Kapitel Herpes-simplex-Virus-Infektionen. In Deutsche

Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen.


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Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 308-313.

39. Schuster V, Nadal D. Kapitel Humanes-Herpesvirus-Typ-6- und -Typ-7- und Typ-8-Infektionen. In

Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 332-337.

40. Magdorf K, Bialek R, Detjen AK, Haas WH, Henneke P, Nadal D, Ritz N. Kapitel Tuberkulose und

nichttuberkulöse mykobakterielle Krankheiten. In Deutsche Gesellschaft für Pädiatrische Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 551-570.

41. Schuster V, Bührer C, Hamprecht K, Müller A, Nadal D. Kapitel Zytomegalovirusinfektionen. In


42. Liese JG, Abele-Horn M, Forster J, Heininger U, Nadal D, Rose MA, Scholz H. Kapitel Pneumonie. In


43. Ehl S, Liese JG, Nadal D. Kapitel Das infektanfällige Kind. In Deutsche Gesellschaft für Pädiatrische

Infektiologie (DGPI) Handbuch: Infektionen bei Kindern und Jugendlichen. Eds. Berner R, Bialek R, Borte M, Forster J, Heininger U, Liese JG, Nadal D, Roos R, Scholz H. Thieme Verlag Stuttgart, 6th Edition 2013, pp 701

e) Varia 1. Nadal D. Antibiotika bei akuter Otitis media? Praxis 1997;85:1790. 2. Nadal D. Behandlung der herpetischen Gingivostomatitis mit Aciclovir bei Kindern. Praxis

1997;86:1867. 3. Nadal D. Schutzimpfungen. Schweiz Ärztezeitung 1998;79:163. 4. Nadal D. Retroviren beim Kind. Unimagazin 1999;2:26-30. 5. Nadal D. Herpes genitalis – die stille Geschlechtskrankheit. Das Neugeborene ist das schwächste

Glied in der Herpes-simplex-Virus-Infektionskette. Hospitalis 2000;70:125. 6. Nadal D. Nützen Antibiotika Kleinkindern mit Otitis etwas? Infomed-Screen 2000;4:29-30. 7. Nadal D. Neuer Meningokokkenimpfstoff. Infomed-Screen 2000;4:55. 8. Nadal D, Berger C, Niggli F. Retroviren beim Kind. Medical Journal 2000;6:25-26. 9. Nadal D. Virusinfektionen beim Menschen. GWA 2001;5:299-303. 10. Nadal D. Akute Sinusitis: keine Vorteile von Antibiotika. Infomed-Screen 2001;5:45. 11. Nadal D. Medicina basada en la evidencia en enfermedades infecciosas pediátricas: controversias.

MTA-Pediatria 2002;23:387-400. 12. Pabst WL, Nadal D, Altwegg M. Diarrheagenic potential of Escherichia coli in children in a developed

country. J Clin Microbiol 2003;41:5836-5837. [Letter]


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13. Nadal D. Comment to: Ashcroft DM, Dimmock P, Garside R et al. Efficacy and tolerability of topical pimecrolimus and tacrolimus in the treatment of atopic dermatitis: meta-analysis of randomised controlled trials. BMJ 2005;330:516-24 in Infomed-Screen 2005;9(5/6):34.

14. Nadal D. Kinderimpfungen: Akzeptanz. Prävention & Gesundheitsförderung im Kanton Zürich

2006;19:6. 15. Nadal D. Antibiotika bei Meningokokken-Verdacht? Infomed-Screen 2006;10:56. MASTER THESES DIRECTED/SUBMITTED BY D. NADAL 1. Sascha Erbetta. Infektion von Tonsillenhistokulturen mit Epstein-Barr-Virus. Masterarbeit Institut für

Pharmazeutische Wissenschaften, ETH Zürich, 2004. 2. Jeannine Leuenberger. TLR9 expression during acute cellular EBV infection. Masterarbeit Institut für

Pharmazeutische Wissenschaften, ETH Zürich, 2004. 3. Selina Elena Decurtins. Silencing of LMP2A gene with siRNA. Masterarbeit Institut für Pharmazeutische

Wissenschaften, ETH Zürich, 2004. 4. Ursina Cagienard. Die Aktivität von viralem LMP2A (im Verhältnis zum LMP2B) ist entscheidend für die

Aktivierung und Beendigung der Tumor fördernden latenten EBV Infektion. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2005.

5. Christina Fehr. Nachweis von Epstein-Barr-Virus (EBV) Replikation mittels Southern blot und ELLISA.

Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2005. 6. Brigitte Kappeler. Erarbeitung eines funktionell steuerbaren RNAi-Systems gegen LMP2 des Epstein-

Barr-Virus. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2005. 7. Matthias Weber. Wirkung von LMP2A und LMP2B auf die Aktivierung der lytischen EBV Infektion in der

BL Zelllinie Akata. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2006. 8. Martina Anna Arnold. Impact of MyD88 on the TLR9 signalling pathway in EBV-positive Burkitt's

lymphoma. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2008. 9. Rahel M. Eugster. LMP2B: effects on viral and cellular signalling in Epstein-Barr virus-transformed B

cells. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2008. 10. Andrea S. Stucki. Conditional activation of the immediate-early lytic genes BZLF1 and BRLF1 of the

oncogenic Epstein-Barr virus. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2008.

11. Ursula Barbara Haussmann. Impact of innate immunity on murine γ-herpesvirus 68 infection and

persistence. Masterarbeit Medizinische Biologie, Universität Zürich, 2008. 12. Anne Marie Theisen. Regulation of Epstein-Barr virus entry into epithelial cells via telomerase and

heparin sulphate. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2009. 13. Natascha Andrea Wuillemin. The role of the EBV lytic promoter in the TLR9-mediated inhibition of lytic

infection. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2009. 14. Tamara Bösch. Real-time qPCR as a valid alternative to plaque assay for the detection and

quantification of MHV-68 levels in various sample types. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2010.

15. Andrea Burch. Establishment of a hormone-inducible system fort he EBV lytic master transcription factor

Zta in Burkitt's lymphoma cell lines. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2011.


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16. Anna Steppacher. Cavitary pulmonary tuberculosis in children hospitalised at the University Children's

Hospital of Zurich 1990-2011. Masterarbeit Medizinische Fakultät, Universität Zürich, 2012. 17. Monika Murat. Role of tlr9 in latent y-herpesvirus infections. Masterarbeit Institut für Pharmazeutische

Wissenschaften, ETH Zürich, 2012. 18. Roberta Aslandogmus. DNA damage response after infection with the tumor-associated Epstein-Barr

virus. Masterarbeit Human Biology, Mathematisch Naturwissenschaftliche Fakultät, Universität Zürich, 2012.

19. Andrina Schumacher. Susceptibility of epithelial AGS cells to infection by cell-free Epstein-Barr virus

mimicking in vivo conditions and establishment of a primary epithelial cell model. Masterarbeit Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2013.

20. Corinne Peng. Age-dependent innate immune response during Epstein-Barr virus infection. Masterarbeit

Institut für Pharmazeutische Wissenschaften, ETH Zürich, 2013. MD or PhD THESES DIRECTED/SUBMITTED BY D. NADAL 1. Agnes Baumann. Akute Mastoiditis im Kindesalter: Eine retrospektive Analyse an 73 Kindern. Med.

Diss., Zürich 1991. 2. Alexander Spillmann. Ueber die Bedeutung von Makroskopie und Mikroskopie in der Schnellerfassung

von experimentellen Bakteriämien mittels des BCB-Systems "Roche". Med. Diss., Zürich 1991. 3. Christian Johannes Taverna. Immunoblot-Untersuchungen bei Kindern mit unterschiedlichen klinischen

Manifestationen der Lyme-Borreliose. Med. Diss., Zürich 1991. 4. Hans Rudolf Briner. Frühsommer-Meningo-Enzephalitis und Lyme-Borreliose bei Forstarbeitern aus

dem Kanton Solothurn: Eine epidemiologische Untersuchung. Med. Diss., Zürich 1992. 5. Tatjana Marva Gass. Die tonsilla palatina: Ein Reservoir für das Epstein-Barr-Virus? Med. Diss., Zürich

1997. 6. Manuel Martin Haschke. Die Rolle respiratorischer Viren bei der Ätiologie der Epiglottitis im Kindesalter.

Med. Diss., Zürich 1997. 7. Lorenzo Lanzicher. Appendicitis perforata im Kindesalter: Trimethoprim-Sulfamethoxazol und

Ornidazol, sowie Bakteriologie und Resistenzverhalten. Med. Diss., Zürich 1999. 8. Sibylle Ziegler. Prädiktive Aussagekraft der Mikroskopie von Trachealsekret intubierter Kinder

bezüglich bakterieller Affektion im unteren Respirationstrakt. Med. Diss., Zürich 1999. 9. Daniel Hardegger. Rapid detection of Mycoplasma pneumoniae in clinical samples by real-time PCR.

Med. Diss., Zürich 2000. 10. Martin Jürgen Blasius. Quantifizierung von Epstein-Barr-Virus in Tonsillen mittels der Real-Time

Polymeraseketten-Reaktion. Med. Diss., Zürich 2001. 11. Oliver Greiner. Quantitative Detection of Streptococcus pneumoniae in Nasopharyngeal Secretions by

Real-Time PCR. Med. Diss., Zürich 2002. 12. Natascia Corti. Antimicrobial Treatment of Acute Haematogenous Osteomyelitis in Children. A review of

114 cases. Med. Diss., Zürich 2002. 13. Christina Saner. Chemokines and matrix metalloproteinases in cerebrospinal fluid from children with

leukemia: relation with involvement of the central nervous system. Med. Diss., Zürich 2003.


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14. Werner Lukas Pabst. Diarrheagenic potential of Escherichia coli in children in a developed country. Med. Diss., Zürich 2003.

15. Mihael Potocki. Prospective survey of antibiotic utilization in pediatric hospitalized patients to identify

targets for improvement of prescription. Med. Diss., Zürich 2004. 16. Claudia Gläser. Detection and molecular characterization of Cryptosporidium spp. isolated from

diarrheic children in Switzerland. Med. Diss., Zürich 2004. 17. Walter Zingg. Impact of an outbreak of Norovirus infection on hospital resources. Med. Diss., Zürich

2004. 18. Laurent Antoine Duttweiler. Pulmonary and systemic bacterial co-infections in severe RSV bronchiolitis.

Med. Diss., Zürich 2005. 19. Bettina Giger. Human tonsillar tissue block cultures differ from autologous tonsillar cell suspension

cultures in lymphocyte subset activation and cytokine gene expression. Med. Diss., Zürich 2005. 20. Adrian Philipp Marty. Detection of Haemophilus influenzae Type b by Real-Time PCR. Med. Diss.,

Zürich 2005. 21. Sara Andrea Klingenfuss. Cytokine measurements in tracheal aspirates of critically ill children with

suspected ventilator associated pneumonia. Med. Diss., Zürich 2007. 22. Sieta Padmaja Rao. Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not

induce switching from latent to lytic Epstein-Barr virus infection in Burkitt’s lymphoma Akata cells. Med. Diss., Zürich 2008.

23. Markus Rechsteiner. Function of latent membrane protein 2B in EBV-positive Burkitt's lymphoma.

Mathematisch-Naturwissenschaftliche Fakultät Diss., Zürich 2008. 24. Marcus Dorner. Impact of innate and adaptive immunity on Epstein-Barr virus infection and persistence.

Mathematisch-Naturwissenschaftliche Fakultät Diss., Zürich 2009. 25. Nadine Payer. Suggested markers for sepsis in critically ill pediatric patients: Accuracy of sCD14, G-

CSF, IL-6, and IL-8 for advanced diagnosis. Med. Diss., Zürich 2009. 26. Ludwig Zauner. Impact of Toll-like receptors on Epstein-Barr virus and Burkitt's lymphoma.

Mathematisch-Naturwissenschaftliche Fakultät Diss., Zürich 2010. 27. Nicole Alexandra Berger. FIP (Fungal Immunomodulatory Protein) of Flammulina velutipes. Med. Diss.,

Zürich 2010. 28. Simone Melanie Brandt-dit-Siméon. Plasma cell toll-like receptor (TLR) expression differs from that of B

cells, and plasma cell TLR triggering enhances immunoglobulin production. Med. Diss., Zürich 2010. 29. Marta Wegmüller. TLR9 triggering-induced suppression of Epstein-Barr virus lytic reactivation in

Burkitt's lymphoma cells requires the full-length episome and is associated with histone modifications on Zppromoter.Med. Diss., Zürich 2013.

PhD THESES COMMITTEE MEMBER 1. Regina Miller. The role of SOCS in HIV infection. Mathematisch-Naturwissenschaftliche Fakultät Diss.,

Zürich 2009. 2. Vanessa Jane Craig. Novel insights into the molecular pathogenesis of gastric MALT lymphoma.

Mathematisch-Naturwissenschaftliche Fakultät Diss., Zürich 2010.


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3. Giovanni Sais. Comprehensive characterization of BKV Large T antigen epitopes to promote the expansion of effectors T lymphocytes across a wide range of HLA class I and II antigens in prostate cancer patients. Mathematisch-Naturwissenschaftliche Fakultät Diss., Zürich 2011.

4. Emilie Zürcher. Characterization of Epstein-Barr virus-encoded latent membrane protein 1.

Mathematisch-Naturwissenschaftliche Fakultät Diss., Lausanne 2012. HABILITATION DIRECTED BY D. NADAL 1. Dr. Christoph Berger. The latent membrane protein 1, a viral oncogene and receptor mimicry in

Epstein-Barr virus-associated reactive and malignant lymphoproliferation. Habilitation Zürich, 2001.

list of publications david nadal, born - universit¤t z¼rich

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