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HEBERDEN SOCIETY overall correlation with the erythrocyte sedimentation rate (Westergren) was found. The serum diphenyl- amine level fell in patients treated with steroid hormones. There were unexplained fluctuations in the level which were not reflected by the E.S.R. The reason for these fluctuations is unknown. The test was therefore found to be a less reliable measure of activity and more time- consuming than the E.S.R. In only two patients with active rheumatoid arthritis and a normal E.S.R. was the diphenylamine level found to be raised. DR. G. R. FEARNLEY, DR. E. G. L. BYWATERS, DR. R. I. MEANOCK, and DR. RITA LACKNER (Postgraduate Medical School of London): "A Comparison of Procaine and Hydrocortisone given by Intra-Articular Injection in Rheumatoid Arthritis". Ten patients suffering from generalized rheumatoid arthritis whose main disability could be ascribed to severe involvement of one knee were selected for a clinical trial. They were placed by random allocation into two groups of five. One group received four fortnightly injections of 50 mg. hydrocortisone acetate into the affected knee and the other group received four fortnightly injections of 4 ml. 2 per cent. procaine. At the end of each course there was a rest period of 2 months, after which the groups were trans- posed, those who had received procaine being given a course of hydrocortisone and vice versa. A variety of assessments were made initially and at each attendance. The most valuable were found to be the sedimentation rate, limitation of extension, joint tenderness, and walking time. Both forms of therapy gave improvement, but the overall effect of hydrocortisone was more dramatic than that of procaine. DR. A. ARONOFF, DR. E. G. L. BYWATERS, and DR. G. R. FEARNLEY (Postgraduate Medical School of London): "Pulmonary Changes in Rheumatoid Arthritis". The incidence of lung lesions in patients with rheumatoid arthritis was compared clinically, radiologically, and post-mortem with that of groups of other patients selected as controls. No specific lung lesion was found in rheumatoid patients which could be characteristically associated with rheumatoid arthritis, and the relative frequency of common pulmonary lesions such as bron- chitis, tuberculosis, and bronchiectasis was about the same in the rheumatoid series as in the controls. It was concluded that if a "rheumatoid lung lesion" exists, it is not common. Annual General Meeting.-This was held at the Royal College of Surgeons, London, on December 4, 1954. The following papers were read: DR. G. D. KERSLEY (Bath): "Changes in the Sacro- iliac and Peripheral Joints in Spondylitis and Rheumatoid Arthritis." DR. B. E. W. MACE (London): "Gout and Pregnancy." DR. ELLIS DRESNER and DR. MAXWELL SCHUBERT (London): "Comparison of Reticulin and Collagen." DR. M. KEECH (Taplow): "Digestibility of Human Skin Collagen by Collagenase in Different Age Groups and Conditions." DR. H. F. WEST (Sheffield): "Effect of 9-fluoro Cortisol Acetate on Adrenal Function." DR. J. C. LEONARD (London): "Potentiation of Corti- sone in Rheumatoid Arthritis." A Symposium on Osteo-Arthritis was given by the following: PROF. D. H. COLLINS (Sheffield): "Pathology of Osteo- Arthritis." DR. G. LOEWI (Cambridge): "Changes which occur in Ageing Cartilage." DR. J. BALL (Manchester): "Joint Changes in Patients with Heberden's Nodes." MR. G. C. LLOYD ROBERTS (London): "Relationship between Symptoms and Lesions." MR. M. H. M. HARRISON (London): "Changes in the Vascular Tree in Osteo-Arthritis." PROF. J. H. KELLGREN (Manchester): Summing up. LIGUE EUROPEENNE CONTRE LE RHUMATISME THIRD EUROPEAN CONGRESS, 1955 Under the High Patronage of H.M. the Queen of the Netherlands The Third European Rheumatology Congress will be organized by the "Nederlandse Vereniging van Rheumatologen", and will be held from June 13-17, 1955, at the Kurhaus, Scheveningen, The Hague. Organizing Committee Hon. President: Dr. J. van Breemen Chairman: E. M. Bingen President Scientific Commission: Prof. Dr. J. Goslings Secretary: Dr. J. J. de Blecourt Treasurer: Dr. P. van der Meer Secretary of the Congress: Members: Dr. H. van Swaay Dr. G. van Dam E. G. van Heusden Dr. R. K. W. Kuipers F. J. F. Steiner Scientific Programme.-This will comprise four sections. Papers will be presented by the following: Section 1. Rheumatic Fever Dr. E. G. L. Bywaters, U.S.-U.K. (England). Prof. F. Coste (France). Dr. P. van der Meer (Netherlands). 373

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Page 1: LIGUE EUROPEENNE CONTRE LEard.bmj.com/content/annrheumdis/13/4/local/admin.pdf · ELLIS DRESNER and DR. MAXWELL SCHUBERT (London): "ComparisonofReticulin andCollagen." DR.M.KEECH

HEBERDEN SOCIETYoverall correlation with the erythrocyte sedimentationrate (Westergren) was found. The serum diphenyl-amine level fell in patients treated with steroid hormones.There were unexplained fluctuations in the level whichwere not reflected by the E.S.R. The reason for thesefluctuations is unknown. The test was therefore foundto be a less reliable measure of activity and more time-consuming than the E.S.R. In only two patients withactive rheumatoid arthritis and a normal E.S.R. was thediphenylamine level found to be raised.DR. G. R. FEARNLEY, DR. E. G. L. BYWATERS, DR.

R. I. MEANOCK, and DR. RITA LACKNER (PostgraduateMedical School ofLondon): "A Comparison of Procaineand Hydrocortisone given by Intra-Articular Injectionin Rheumatoid Arthritis". Ten patients suffering fromgeneralized rheumatoid arthritis whose main disabilitycould be ascribed to severe involvement of one knee wereselected for a clinical trial. They were placed by randomallocation into two groups of five. One group receivedfour fortnightly injections of 50 mg. hydrocortisoneacetate into the affected knee and the other groupreceived four fortnightly injections of 4 ml. 2 per cent.procaine. At the end of each course there was a restperiod of 2 months, after which the groups were trans-posed, those who had received procaine being given acourse of hydrocortisone and vice versa. A variety ofassessments were made initially and at each attendance.The most valuable were found to be the sedimentationrate, limitation of extension, joint tenderness, and walkingtime. Both forms of therapy gave improvement, but theoverall effect of hydrocortisone was more dramatic thanthat of procaine.DR. A. ARONOFF, DR. E. G. L. BYWATERS, and

DR. G. R. FEARNLEY (Postgraduate Medical School ofLondon): "Pulmonary Changes in Rheumatoid Arthritis".The incidence of lung lesions in patients with rheumatoidarthritis was compared clinically, radiologically, and

post-mortem with that of groups of other patientsselected as controls. No specific lung lesion was foundin rheumatoid patients which could be characteristicallyassociated with rheumatoid arthritis, and the relativefrequency of common pulmonary lesions such as bron-chitis, tuberculosis, and bronchiectasis was about thesame in the rheumatoid series as in the controls. It wasconcluded that if a "rheumatoid lung lesion" exists, itis not common.

Annual General Meeting.-This was held at theRoyal College of Surgeons, London, on December 4,1954. The following papers were read:DR. G. D. KERSLEY (Bath): "Changes in the Sacro-

iliac and Peripheral Joints in Spondylitis andRheumatoid Arthritis."

DR. B. E. W. MACE (London): "Gout and Pregnancy."DR. ELLIS DRESNER and DR. MAXWELL SCHUBERT

(London): "Comparison of Reticulin and Collagen."DR. M. KEECH (Taplow): "Digestibility of Human Skin

Collagen by Collagenase in Different Age Groupsand Conditions."

DR. H. F. WEST (Sheffield): "Effect of 9-fluoro CortisolAcetate on Adrenal Function."

DR. J. C. LEONARD (London): "Potentiation of Corti-sone in Rheumatoid Arthritis."

A Symposium on Osteo-Arthritis was given bythe following:

PROF. D. H. COLLINS (Sheffield): "Pathology of Osteo-Arthritis."

DR. G. LOEWI (Cambridge): "Changes which occur inAgeing Cartilage."

DR. J. BALL (Manchester): "Joint Changes in Patientswith Heberden's Nodes."

MR. G. C. LLOYD ROBERTS (London): "Relationshipbetween Symptoms and Lesions."

MR. M. H. M. HARRISON (London): "Changes in theVascular Tree in Osteo-Arthritis."

PROF. J. H. KELLGREN (Manchester): Summing up.

LIGUE EUROPEENNE CONTRE LE RHUMATISME

THIRD EUROPEAN CONGRESS, 1955Under the High Patronage of H.M. the Queen of the Netherlands

The Third European Rheumatology Congress willbe organized by the "Nederlandse Vereniging vanRheumatologen", and will be held from June 13-17,1955, at the Kurhaus, Scheveningen, The Hague.

Organizing CommitteeHon. President: Dr. J. van BreemenChairman: E. M. BingenPresident Scientific Commission: Prof. Dr. J. GoslingsSecretary: Dr. J. J. de BlecourtTreasurer: Dr. P. van der Meer

Secretary of the Congress:Members:

Dr. H. van SwaayDr. G. van DamE. G. van HeusdenDr. R. K. W. KuipersF. J. F. Steiner

Scientific Programme.-This will comprise four sections.Papers will be presented by the following:

Section 1. Rheumatic FeverDr. E. G. L. Bywaters, U.S.-U.K. (England).Prof. F. Coste (France).Dr. P. van der Meer (Netherlands).

373

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ANNALS OF THE RHEUMATIC DISEASESSection 2. Connective TissueDrs L. E. Glynn, R. Consden, J.

E. G. L. Bywaters (England).Prof. G. C. Heringa (Netherlands).Dr. G. Asboe-Hansen (Denmark).Dr. Morris Ziff (U.S.A.).

Holborow, and

Section 3. Osteo-Arthritis of the Spine and DiskDegeneration

Prof. Sten Friberg (Sweden).Prof. S. de Seze and Dr. J. Lacapere (France).Dr. P. Barcelo and Dr. J. M. Vilaseca Sabater

(Spain).Prof. H. Junghanns (Germany).

Section 4. Rheumatism and Social MedicineDr. R. J. Weissenbach and Dr. F. Franqon (France).Prof. K. M. Walthard (Switzerland).Prof. A. Masturzo (Italy).Prof. E. W. Baader (Germany).Drs. M. Ruelle and A. Henrard (Belgium).

These papers will be presented in plenary sessions.The discussions will be opened immediately after thepresentation of the reports.Members who wish to deliver short papers (maximum

10 minutes) on these or other subjects are requested toforward the titles to the Secretariat. Summaries of100-150 words in any two of the four congress languages(English, French, German, Spanish) must be submittedbefore January 1, 1955. The Organizing Committeewill decide the acceptance or refusal of these com-munications.Film demonstrations will also be arranged, and there

will be a scientific exhibition in the Kurhaus; memberswho wish to contribute are requested to apply beforeJanuary 1, 1955. There will also be an exhibition ofmedical and pharmaceutical products. Interested firmsmay obtain further information from the Secretariat.

Social Programme.-A day excursion to Amsterdam,planned for June 15, is open to all members. A trip

through the canals of the ancient city will be providedthrough the generosity of the Municipality of Amsterdam,and there will be an official reception by the NetherlandsGovernment at the Rijksmuseum. On June 17 therewill be a social evening with buffet-supper for all membersof the Congress.A special ladies' committee will arrange for the enter-

tainment of the associate members.The Committee is considering the possibility of organ-

izing a post-congress sight-seeing tour through theNetherlands and Belgium, combined with a few scientificmeetings. The tour will last about seven days andmembers of the Congress will have the opportunity ofseeing the most famous works of art of the two countries.

Registration Fee (including all social events and excur-sions): Active members, 100 Neth. florins (includingCongress Proceedings); Associate members, 60 Neth.florins.Exchange rates (approximate):

£1 = 10 70 Neth. florins;$1 = 3 80 Neth. florins.

Bank.-Amsterdamsche Bank N.V., The Hague.

Accommodation.-The price of hotel rooms at Scheven-ingen varies from 8 50 to 32 Neth. florins, dependingupon the hotel category (five classes), the location, andthe bath facilities. Breakfast is always included, andfor a stay of five or more days partial board can bearranged.

Further details concerning the technical pro-gramme, registration, methods of payment, hotelreservations, film demonstrations, exhibitions, enter-tainment, and excursions and registration forms willbe supplied on application.

All correspondence should be addressed to theSecretariat of the Congress: Burg. De Monchyplein9, The Hague, Netherlands. Tel. 185281.

CHARTERED SOCIETY OF PHYSIOTHERAPY

Annual Congress, 1954

The annual congress of the Society was held at Harro-gate from September 8-12, 1954. The following lecturesand discussions dealt with various aspects of rheuma-tology:

PROF. S. J. HARTFALL: "Stress factors in the Aetiologyof the Rheumatic Diseases".

DR. W. YEOMAN: "Physiotherapy in the Treatment ofRheumatic Disorders".

MR. R. BROOMHEAD: "Management of SurgicalTreatment of Arthritis of the Hip".

MR. H. PETrY: "Orthopaedic Management of Rheu-matoid Arthritis".

MR. M. ELLIS: "Soft Tissue Lesions of Ankle andShoulder".

374

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NUFFIELD FOUNDATION

GRANTS FOR RESEARCH IN RHEUMATISMDuring the past 5 years the Nuffield Foundation

has been'supporting much chemical and other workon adrenal hormones, but it is now reverting to itsoriginal policy of supporting fundamental andclinical research into the nature of the rheumaticdiseases.To the University of Manchester Rheumatism

Research Centre, an additional grant of £70,000payable over the coming 8 years is made to extendthe work under the director, Professor J. H.Kellgren.At the Northern General Hospital, Edinburgh, the

Foundation is providing a new building for theRheumatic Unit on an adjoining site to houseconsulting and research rooms, clinics, and labora-

tories, at a cost of £27,000. The new building willbe ready by the end of 1954. In addition, theFoundation will continue its annual grant to assistthe unit's work, and over the 5 years 1954-1958 itwill provide £38,000 for this purpose.In addition, two smaller grants have been offered

to other rheumatism centres: £8,000 to the Universityof Sheffield to finance a research fellowship at theSheffield Centre for the Investigation and Treatmentof Rheumatic Diseases, directed by Dr. H. F. West,and £6,000 to the Oxford Regional Hospital Boardfor an experimental pathologist to work on thepathogenesis of rheumatic diseases under Dr.A. G. S. Hill at the new Rheumatic DiseasesResearch Centre, Stoke Mandeville Hospital, Bucks.

EMPIRE RHEUMATISM COUNCIL

COURSE FOR CONSULTANTSThe British Postgraduate Medical Federation and

Empire Rheumatism Council will hold a course forconsultants on Modem Aspects of Rheumatic Disease

at the Arthur Stanley Institute, Middlesex Hospital, andthe Postgraduate Medical School, London, on March24-26, 1955.

LIGA MEXICANA CONTRA EL REUMATISMOOfficers, 1954-1955

President: Dr. Javier Robles GilVice-President: Dr. Salvador Aceres

Secretary: Dr. Manuel BoesterlyTreasurer: Dr. Armando Cuellar

375

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INDEX TO VOLUME XIII, 1954* indicates that only the title of the article is given

Abu Mansur, 194Achilles tendon, pathology of, in arthritis, rheumatoid, 43Achillodynia, 50Acid, hyaluronic, nature of, 361

hydrobenzoic in rheumatic fever, 60salicylic, and oxygen consumption, 60uric, aspirin and, 238

in gout, 120, 233, 366probenecid and, 238in serum, phenylbutazone and, 318sodium salicylate and, 238urinary, 121

phenylbutazone and, 318Acqui Prize, 1954, 257Acromegaly, 53Acroparaesthesia in spondylosis, 10ACTH in ankylosing spondylitis, 109, 188

dosage schedule, 309and pathological fractures, 363production of, in conditions of stress, 102and serum levels in rheumatic disease, 214gel, highly purified, in rheumatoid arthritis, 56

ACTHAR: See ACTHAcute rheumatism: See Rheumatism, acuteAdaptation syndrome, 102Addison's disease, 9-x-fluoro hydrocortisone acetate in, 291ADLER, E., and MAYBAUM, S.: Rare features in a case of Gaucher's

disease, 229Adrenal cortex and homeostasis, 346Adrenalectomy, experimental, 103Adrenocortical steroids, antiphlogistic influence of, 346

metabolism of, in synovium, 347Adrenogenital syndrome, 9-Oc-fluoro hydrocortisone acetate in, 291Agglutination, sheep cell, 279, 302, 306Albumin/globulin levels in plasma in arthritis and spondylitis, 209Alexander of Tralles, 193Allergens, streptococcal, hypersensitivity to, and arthritis, rheuma-

toid, 325Allo-dihydro-hydrocortisone, 297, 354*AMATULLI, G., 75American Rheumatism Association Annual Meeting, 1954, Pro-

ceedings, 344Cooperative Study of Cortisone Therapy in RheumatoidArthritis, Interim Report, 349

Presidential Address, 344Amino acids and nutrition in rheumatism, acute, 324Amyloidosis in arthritis, rheumatoid, 372 bisAnaemia of arthritis, rheumatoid, 365Androsterone, 67Ankylosing spondylitis: See Spondylitis, ankylosingAnnulus, protrusion of, in intervertebral disk, 3Appendicectomy, arthritis, rheumatoid, and, 341Arab physicians, 194Argyrophilia, 30ARONOFF, A., *256, 373Arteritis of arthritis, rheumatoid, 136--, temporal, and rheumatic disease, 136Artery, lesions of, and arthritis, rheumatoid, 277Arthritis and Rheumatism Foundation, U.S.A., Cleveland Chapter,

257Arthritis, classification of, 361

chronic, psycho-social factors in rehabilitation, 312experimental, production of, 103-, response to cortisone, 105-, synovo-toxic antiserum tagged 1311 in, 369gouty, colchicine in, 367

phenylbutazone in, 317rheumatoid, anaemia of, 365

amyloidosis in, 372 bisarteritis of, 136aspirin in, 351

-, bone marrow in, 327and carcinoma, pulmonary, 52

-, cortisone in, 201, 207, 302, 304, 349, 351, 352diphenylamine in, 372gold therapy, 201, 208-, and erythrocyte sedimentation rates, 336

- , heel lesions in, 42-- histochemical study of nodules of, 28

hormone therapy, analgesic and suppressive, in, 307

391

Arthritis, rheumatoid, hydrocortisone in, 297, 354 bis, 368, 373juvenile, spondylitis in, 364and keratoconjunctivitis sicca, 372metabolism of adrenal cortical steroids in synovia

cavity, 347phenylbutazone in, 201, 208placental tissue implantation in, 63plasma proteins in, 201and polyarteritis nodosa, 277post-partum plasma in, 131procaine, intra-articular and, 373pulmonary changes in, 52, 373remissions in, 362shoulder lesions in, 157serum levels in, 212, 213surgery and, 341thyroidectomy in, 250zone electrophoresis in, 201

Arthropatny, pararheumatic and polyarteritis nodosa, 277Arthroplasty in ankylosing spondylitis, 188ASLING, C. W., 346Aspirin and cortisone acetate in arthritis, rheumatoid, 351Autopsy in polyarteritis, 277Autumn crocus: See Colchicum

BACH, F. J., *74, *75*BADIN, J., 167BAIRD, J. P., 74*BALL, J., 373_: Rheumatoid arthritis and polyarteritis nodosa, 277BARKIN, R., 364BARTFELD, H., 70Batchelor's pseudarthrosis, 188*BATTEN, G., 75BAUER, W., 352, 362Bauhin, Caspar, 194BAYLES, T. B., 348, 365, 369BEATTIE, J. W., 256BEAUREGARD, J. M., 362"Benemid": See ProbenecidBERGENSTAL, D. M., 360Bicillin: See N,N' Dibenzylethylenediamine dipenicillin GBICKELL, W. H., 353Bile-duct, obstruction of, and suppression of inflammation, 102BILLIMORIA, J. D., 164Biopsy of heel in rheumatoid arthritis, 47

in polyarteritis, 277of sternal bone marrow, 327

-of synovium in diagnosis, 353BLtCOURT. J. J. DE: "Screening" of the population for rheumatic

diseases, 338Blood, complementary activity of, in rheumatic disease, 211

electrophoresis in study of, 201pregnancy, in rheumatoid arthritis, 133vessels, peripheral, cortisone and, 302

BLUMBERG, B., 361Bock, Hieronymus, 195BOLAND, E. W., 348

and HEADLEY, N. E.: Preliminary clinical trials with 9-alpha-fluoro hydrocortisone acetate in rheumatoid arthritis, 291

Bone, histology and radiology of, in spondylitis, 222marrow in arthritis, rheumatoid, 327

BOOK REVIEWS:ASBOE-HANSEN, G. (edited by): Connective tissue in health and

disease, 1954, 371BUETTI-BAUML, C.: Funktionelle rontgendiagnostik der halsweib-

saule, 1954, 372BYWATERS, E. G. L.: Canadian Red Cross Memorial Hospital

Report, 1953, 252COPEMAN, W. S. C.: West London Hospital Report, 1953, 252CYRIAX, J.: Textbook of orthopaedic medicine. Vol. I. Diag-

nosis of soft tissue lesions, 1954, 370FLETCHER, E. T. D.: Royal Free Hospital Report, 1953, 252HouLI, J.: Espondilite anquilosante, 1954, 370REVISTA ESPANOLA DE REUMATiSMO: VIII Congreso Internacional

de Enfermedades Reumaticas, 1953, 163RoTIs-QuERoL, J.: Tratamiento de los Reumatismos, 252STEINBERG, C. L.: Arthritis and rheumatism: the diseases and

their treatment, 1954, 370

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392 ANNALS OF THE RhBOOK REVIEWS:TRAUT, E. F.: Rheumatic Diseases, 1952, 71WHO Expert Committee on Rheumatic Diseases. First Report,

1954, 253*BOSCH, S. J., 167BOWIE, M. A., 354

See HOLLANDER, J. L., BROWN, E. M., Jr., JESSAR, R. A.,UDELL, L., SMUKLER, N., and BOWIE, M. A.

BRAIN, R.: Heberden Oration, 1953. Spondylosis: The knownand the unknown, 2

* ,72Brazil, chair of rheumatology, 71, 167BRENNER, J. M., 256British Empire Postgraduate Medical Federation, 375British Rheumatic Association, 71BRODIE, B. B., 347BROOMHEAD, R., 256, *374BROWN, E. M., 354BROWN, E. M., Jr.: See HOLLANDER, J. L., BROWN, E. M., Jr.,

JESSAR, R. A., UDELL, L., SMUKLER, N., and BOWIE, M. A.*BROWN, P., 167Brunschwig, Hieronymus, 194

*BULASHENKO, H., 75BUNIM, J. J., 347, 348, 352, 365Bursitis, sub-Achilles, 50--, sub-acromial, 159Butazolidin: See PhenylbutazoneBYWATERS, E. G. L.: Heel lesions of rheumatoid arthritis, 42

*256, 373 bisByzantine physicians, 194

*CAHN, J., 75Calcification, para-articular, in paraplegia, 372Calcinosis of vessels and joints, heredo-familial, 15CALKINS, E., 352Canadian Rheumatism Association, Officers, 1954-55, 257Carcinoma of lung simulating rheumatoid arthritis, 52Carditis, rheumatic, and arthritis, rheumatoid, 137

, in children, 359Caronamide and uric acid excretion, 234Cartilage, biopsy of, 224

degeneration in arthritis, rheumatoid, 42extracts and inhibition of cortisone effect, 361

-, pannus in, 285, 286, 287radioactive sulphur uptake of, hypophysectomy and, 360

*CASOLO, G., 75CATCHPOLE, B. N., JEPSON, R. P., and KELLGREN, J. H.: Peripheral

vascular effect of cortisone in rheumatoid arthritis, sclero-derma, and other related conditions, 302

*CAYLA, F., 257CECIL, R. L., 350, 362Cervical spine, pathology of, 9, 11Chartered Society of Physiotherapists, Annual Congress, 1954, 374CHATELIN, N. H., 368Children, haemolytic streptococcal infection in, 355

rheumatic carditis in, 359spondylitis and arthritis in, 364

Cholecystectomy, arthritis, rheumatoid, and, 341Circulation of blood, cortisone and, 302CLARK, W. S., 363Cleveland, Ohio, 257Colchicine in gout, 163, 190, 233

intravenous, in gouty arthritis, 367isolation, chemistry, and action of, 196radioactive, C14 labelled, 197in tumours, 197

Colchicum, history of use in gout, 190Collagen disease, hormone therapy in, 310

- rheumatism, acute, as, 324presence of, in nodules, 30

Collagenase, action of, on nodules, 28*COLLICELLI, A., 75CONGRESSES:American Rheumatism Association, 344Arthritis and Rheumatism Foundation, 257British Rheumatic Association, 71Chartered Society of Physiotherapists, 375European League against Rheumatism, 373Heberden Society, 72, 74, 255, 256, 372, 373New York Rheumatism Association, 167

CORRESPONDENCE:Colchicine in gout, 163Trafuril, 70

Corticoids, antiphlogistic effect of, 102Corticosteroids, 56Corticotrophin: See ACTHCortisone in arthritis, rheumatoid, 201, 252 bis, 349, 351

acetate and aspirin in arthritis, rheumatoid, 351dosage schedule, 309and erythrocyte sedimentation rate, 302and experimental inflammation, 103inhibition by cartilage extracts, 361

YEUMATIC DISEASESCortisone metabolism in long-term therapy, 352

and pathological fractures, 363and peripheral vessels, 302and plasma, rate of disappearance from, 347in Reiter's syndrome, 161and serum levels in rheumatic disease, 214and skin temperature, 304

--in spondylitis, ankylosing, 188, 201COURSES:

British Empire Postgraduate Medical Federation, 1955, 375Empire Rheumatism Council, 1955, 375Fellowship of Postgraduate Medicine, 1854, 75Rome Rheumatology Day, 1954, 75University of Havana, 1954, 257

Coxsackie virus infection, histopathology of sarcolemma andsarcoplasm in, 35

Cramp, 331Creatinine excretion, 317*CRITTENDEN, J. O., 75Crocus, autumn: See ColchicumCRUICKSHANK, B.: The arteritis of rheumatoid arthritis, 136COBB, S., 361

*COLLINS, D. H., 373*CUDKOWICZ, L., 75Culpeper, Nicolas, 195*CURTARELLI, G., 75CURTISS, P. H., 363

*DALEY, R., 75*DARBY, P. W., 74DE COEK, N., 372*DELBARRE, F., 257Demetrius Pepagomenus, 194DENKO, C. W., 360Dermatitis in gold therapy, 337Dermatomyositis and arteritis, 136

cortisone and, 303hormone therapy in, 310

Desoxycorticosterone acetate (DOCA) and experimental inflam-mation, 103

Diabetes and rheumatism, acute, 325Diet and rheumatism, acute, 324Dinitro-o-cresol, 61Dioscorides, 192Diphenylamine reaction in arthritis, rheumatoid, 372Disk, intervertebral, biopsy of, 224

A,-, degeneration of, 2DIXON, A. ST. J., 366DOCKERTY, M. B., 353DODGE, H. J., 359*DOHAN, F. C., 75DOUGHERTY, T. F., 346*DRESNER, E., 373Dropsy, colchicum in, 195DUCKETT JONES, T., 358DUFF, I. F., 354, 369

Editorial, 1, 101, 185Eggs and protein deficiency in rheumatism, acute, 324*EHRLICH, M. E., 167Electromyograph studies of painful muscles, 331Electrophoresis in study of plasma proteins, 201

*ELLIS, M., 374*ELLMAN, P., 75EMERSON, C. P., 365Empire Rheumatism Council:

17th annual report, 164Officers, 1954-55, 166Course for consultants, 1955, 375

Endocarditis, bacterial, and arteritis, 136Endotoxins and fibrinoid necrosis, 359ENGFELDT, B., ROMANUS, R., and YDE9N, S.: Histological studies of

pelvo-spondylitis ossificans (ankylosing spondylitis) cor-related with clinical and radiological findings, 219

Enzyme preparations, action of, on nodules, 28Eosinophil reactions and gold therapy, 337Eosinophilia in arthritis, rheumatoid, 328Ephemeron: See ColchicumErosion in heel bones, 51Erythema, palmar, 53Erythrocyte sedimentation rate, cortisone and, 302

gold therapy and, 336plasma fibrinogen level and, in arthritis and

spondylitis, 201Etiocholanolone, 67Euricius Cordus, 194European League against Rheumatism, 373EVANS, H. M., 346

FAIRBANKS, R., *167, 347FAVOUR, C. B., 369

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INDEXFAWNS, H. T., and LANDELLS, J. W.: Histochemical studies of

rheumatic conditions. II. The nodule of rheumatoidarthritis, 28

FEARNLEY, G. R., *256 ter, 372 bis, 373 bisFellowship of Postgraduate Medicine, Rheumatism course, 1954, 75Fever, rheumatic: See Rheumatism, acuteFibrinogen level in plasma, 201Fibrinoid, presence of, in nodules, 31Fibrosis of nerve roots, 7Fibrositis, 331FINCH, S. C., 365FINN, N., 163FLETCHER, ERNEST, 362*FLETCHER, E. T. D., 167FORESTIER, J., 74

*FOSTER, V., 167Fractures, pathological, and steroid hormone therapy, 363Franklin, Benjamin, 195*FREEDMAN, A., 74FREIREICH, E. J., 365FREYBERG, R. H., 354, 365"Frozen" shoulder, 159

novocaine in, 231Fuchs, Leonhart, 194

GEIGER, J.: See NEUSTADT, D. H., GEIGER, J., and STEINBROCKER, 0.Galen, 193Garrod, work on gout, 196Gastro-intestinal symptoms in hormone therapy, 308Gaucher's disease, 229Geoffroy, Stephen Francis, 195*GEORGES, G., 75GIBSON, G., and NORYMBERSKI, J. K.: A note on the rapid assay of

17-ketogenic steroids in urine, 59Gilbertus Anglicus, 194Girdlestone's pseudarthrosis, 188Glucocorticoid properties of hydrocortisone, 291Glutathione metabolism, 325Gold therapy in arthritis, rheumatoid, 201

in spondylitis, ankylosing, 201complications and erythrocyte sedimentation rate, 336

GOLDTHWAIT, J. C., 369GOODSON, W. H., Jr., 356*GOULD, I., 167Gout and arteritis, 136

colchicum in, 163, 190, 367probenecid in, 120, 233sodium salicylate in, 233uric acid excretion in, 366

GRAHAM, W., 367Granuloma annulare and arteritis, 136Greek physicians, 193Greven, Jaques, 195Group-A haemolytic streptococci in rheumatism, acute, 324Growth hormone and arthritis, experimental, 346

and radioactive sulphur uptake of cartilage, 360GUERRA, S. L., 347GUTMAN, A. B., *167, *257, 366

HALL, D. A., 255Halogen derivatives of hydrocortisone, 291*HARDING, H. E., 75*HARRISON, M. H. M., 373HART, F. DUDLEY, 74, *75, 164

: Ankylosing spondylitis: a survey, 186HARTFALL, S. J., *75, 256, *374HARTUNG, E. F., 70- History of the use of colchicum and related medicaments in

gout, 190Havana, University of, Summer School, 1954, 257*HAYDU, G. G., 167HEADLEY, N. E.: See BOLAND, E. W., and HEADLEY, N. E.HEALD, L.: See LOWMAN, E. W., MILLER, S., LEE, P. R., STEIN, H.,

KING, R., and HEALD, L.Heberden Oration, 1953, 2

, 1954, 256, 372Round, 1954, 255Society Annual Dinner, 1953, 72

Annual 1954, 256-Annual Meeting, 1954, 256

Annual Report, 1953, 72Clinical Meetings: December 5, 1953, 74

February 26, 1954, 74May 8, 1954, 256September 25, 1954, 256December 4, 1954, 375

Heel lesions in rheumatoid arthritis, 42HENCH, P. S., 352, 353Henoch-Schonlein purpura and arteritis, 136Herbstzeitlose: See ColchicumHeredity and calcinosis, 15- and spondylitis, ankylosing, 186

393HERNDON, C. H., 363Hermodactyl: See ColchicumHerniation of intervertebral disks, 2HILL, R.: See HUFFMAN, E. R., WILSON, G. M., SMYTH, C. J., and

HILL, R.Hip joint, injection into, 246HIRSCHFELD, I., 358Histology of bone marrow in arthritis, rheumatoid, 328

of polyarteritis nodosa, 277of spondylitis, ankylosing, 220

HOLLANDER, J. L., *75, 347, 354, 368BROWN, E. M., JR., JESSAR, R. A., UDELL, L., SMUKLER, N.,and BOWIE, M. A.: Local anti-rheumatic effectiveness ofhigher esters and analogues of hydrocortisone, 297

HOLOPAINEN, T. E.: See LAINE, V. A. I., VAitIo, K. J., and HOLO-PAINEN, T. E.

Homeostasis, adrenal cortex in, 346Hormone therapy, analgesic, 307, 354

by placental tissue implantation, 65suppressive, 307, 354

HOULI, J., 71, 167and MoNTEmIo MARINHO, H.: Bone marrow in rheumatoid

arthritis, 327H.P. Acthar Gel: See ACTHHUFFMAN, E. R., WILSON, G. M., SMYTH, C. J., and HILL, R.:

Metabolic effect of phenylbutazone in gouty and non-goutyarthritis, 317

366HUMBLE, J. G., 74HUNT, T. E., and TREW, J. A.: Zone electrophoretic studies of plasma

proteins in rheumatoid arthritis and ankylosing spondylitis,201

Husson, Nicolas, 196Hyalase, action of, on nodules, 28Hydrobenzoic acid and oxygen consumption, 60Hydrocortisone, 109-acetate, intra-articular, 297

-, 9-alpha-fluoro, in arthritis, rheumatoid, 291benzoate, 297, 354caprylate, 297, 354free alcohol, 293higher esters and analogues of, intra-articular, 297, 354

-intra-articular, 246, 368, 373and plasma, rate of disappearance from, 347t-butyl acetate, 297, 354

Hyperaemia time, cortisone and, 305Hyperglobulinaemia, 325Hypophysectomy and radioactive sulphur uptake of cartilage, 360

1131 and experimental arthritis, 369Ibn-El-Beithar, 194Implantation of placental tissue in rheumatoid arthritis, 63Incidence of rheumatic disease, 253, 338Inflammation, suppression of, by systemic stress, 102INGLE, D. J., 346Injection of hip joint, 246Insulin and rheumatism, acute, 325Intestine, polyarteritis nodosa in small artery of, 285Iritis and spondylitis, ankylosing, 187

*IRVINE, J. H., 167Italian Society of Rheumatology, 75, 257

JIRVINEN, K. A. J., and KUMLIN, T.: Carcinoma of the lung simulat-ing early rheumatoid arthritis, 52

Jaundice, obstructive, and inflammation, 102JEPSON, R. P.: See CATCHPOLE, B. N., JEPSON, R. P., and KELLGRIN,

J. H.JESSAR, R. A., 354

See HOLLANDER, J. L., BROWN, E. M., JR., JEssAR, R. A.,UDELL, L., SMUKLER, N., and BOWIE, M. A.

Joint, acromio-clavicular, 158biopsy of, 222calcinosis of, familial, 15erosion of, 283, 287fibrosis in, 283, 287involvement in spondylitis, ankylosing, 187sacro-iliac, in osteitis condensans i1ii, 150scapulo-humeral, 157sterno-clavicular, 158tissue, polyarteritis nodosa in, 281

Jones, Edwin Godden, 196*JONES, T. DUCKETT, 257

KALLIOMAKI, L.: Correlation of the erythrocyte sedimentation rateand gold complications in rheumatoid arthritis, 336

Role of various surgical operations in the history of patientswith rheumatoid arthritis, 341

KAMMERER, W. H., 367KC1, 309*KEECH, M., 373KELLETT, C. E.: Complementary activity of the blood in rheumatism

and certain allied disorders, 211

11

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ANNALS OF THE RHEUMATIC DISEASESKELLEY, V. C., 356KELLGREN, J. H., 373-: See CATCHPOLE, B. N., JEPSON, R. P., and KELLGREN, J. H.

*KENDELL, H. W., 257KENYON, A. T., 360Keratoconjunctivitis sicca and arthritis, rheumatoid, 372*KERSLEY, G. D., 373KEY, J. A., 369Kidney function in gout, 366

perivascular fibrosis, 284polyarteritis nodosa in, 287

KING, R.: See LOWMAN, E. W., MILLER, S., LEE, P. R., STEIN, H.,KING, R., and HEALD, L.

KINSELL, L. W.: Suppressive as compared with analgesic hormonaltherapy in patients with rheumatoid arthritis, 307

354*KLEIN, R., 167Klippel-Feil deformity of shoulder, 159Knee, hydrocortisone injections into, 297KOMINZ, J. S., 368KOUMANS, A. K. J.: See LANDSMEER, J. M. F., and KOUMANS,

A. K. J.KUMLIN, T.: See JARVINEN. K. A. J., and KUMLIN, T.

LACKNER, R., *256 ter, 372 bis, 373*LAI, L., 75LAINE, V. A. I., VAINIO, K. J., and PEKANMAKI, K.: Shoulder

affections in rheumatoid arthritis, 157and HOLOPAINEN, T. E.: Effect of thyroidectomy in

rheumatoid arthritis, 250LANDELLS, J. W.: See FAWNS, H. T., and LANDELLS, J. W.LANDSMEER, J. M. F., and KOUMANS, A. K. J.: Anatomical con-

siderations in injection of the hip joint, 246LATTES, R., 361"L.E." cells in arthritis, rheumatoid, 328LEE, P. R.: See LOWMAN, E. W., MILLER, S., LEE, P. R., STEIN, H.,

KING, R., and HEALD, L.LEONARD, J. C., 74, *373Leukopenia and gold therapy, 337Li, C. H., 346LICHTY, J. A., 359Liga Mexicana contra el Reumatismo: See Mexican League against

RheumatismLigue Europeenne contre le Rhumatisme: See European League

against RheumatismLinnaeus, Carl, 195Liver, role of, in suppressing inflammation, 102

polyarteritis nodosa in, 282, 284*LLOYD ROBERTS, G. C., 373*LOEWI, G., 373LONG, D. A.: Rheumatic fever as a collagen disease, 324*LOWMAN, E. W., 167

MILLER, S., LEE, P. R., STEIN, H., KING, R., and HEALD, L.:Psycho-social factors in rehabilitation of the chronicrheumatoid arthritic, 312

*LUCHERINI, T., 75Lumbar spine, pathology of, 12*LUNEDI, A., 75Lung, carcinoma of, simulating early rheumatoid arthritis, 52-changes in arthritis, rheumatoid, 373Lupus erythematosus and arteritis, 136

fibrinoid deposits in, 359hormone therapy in, 310serum levels in, 212, 215

MACDONALD, C., 365McEWEN, C., *167 bis, 347, 349, 352MACLAGAN, N. F., 164MACLEOD, I., 166MACE, B. E. W., 373MAGGI, C. A., 75

*MANCINI, B., 75Manipulation, contraindicated in ankylosing spondylitis, 188Marie-Strumpell's disease: See Spondylitis, ankylosingMarrow, bone, in arthritis, rheumatoid, 327MARSON, F. G. W.: Sodium salicylate and probenecid in the treat-

ment of chronic gout, 233* 256*MARTIN, E., 75MARTIN, J. R., 361MASON, R. N.: Studies on the effect of probenecid ('Benemid') in

gout, 120*MASTURZO, A., 75MATTHEWS, B. F., 164Mattioli, 195MAYBAUM, S.: See ADLER, E., and MAYBAUM, S.MEADE, B. W.: Effect of certain hydroxybenzoic acids on the

oxygen consumption of Wistar rats, 60*MEANOCK, I., 256MEANOCK, R. I., 373

*MELLONI, F., 75MERCHANT, W., 361

Mesue, John, 194Metabolism of adrenal cortical steroids in synovial cavity, 347-, phenylbutazone and, 317Mexican League against Rheumatism, 375MEYER, K., 361MIKKELSEN, W. M., 368MILLER, S.: See LOWMAN, E. W., MILLER, S., LEE, P. R., STEIN, H.,

KING, R., and HEALD, L.Mineralocorticoid properties of hydrocortisone, 291MISSEN, G. A. K., 372MITCHELL, D. M., 352MONTEIRO MARINHO, H.: See HoULI, J., and MONTEIRO MARINHO, H.MOON, H. D., 346Morphology of spondylitis, ankylosing, 227MORRISON, R. J. G., 74*MOTTA, L., 75MUIR, I. H. M., 165Muscle activity, electrical recording of, 332

fibre, diameter of, in Coxsackie virus infection, 35spasm as cause of pain, 331tissue, polyarteritis nodosa in, 282

, wasting of, in cervical spondylosis, 10Myelopathy in spondylosis, 11

N,N' Dibenzylethylenediamine dipenicillin G, in rheumatism, acute,358

Necrosis, fibrinoid, endotoxins and, 359Nephritis, serum levels in, 212Nerve, radicular, fibrosis of, 7Nervous system, disk degeneration and, 2Netherlands, incidence of rheumatism in, 338

, III European Congress of Ligue Europeenne, 1955, 373Neuritis, foraminal pressure and lumbar disk protrusion, 12Neurology of osteo-arthritis of cervical spine, 363NEUSTADT, D. H., GEIGER, J., and STEINBROCKER, O.: Effect of post-

partum plasma in rheumatoid arthritis, 131NEUWIRTH, E., *167, 363New York Rheumatism Association, Annual Meeting, 1954, 167NEWNS, G. R.: See WEST, H. F., and NEWNS, G. R.Nicander, 192*NICOLA, P. DE, 75Nodes, articular, 18Nodules, 350

histochemical studies of, 28subcutaneous, 279

Nomenclature of rheumatic disease, 253NORYMBERSKI, J. K., 164

See GIBSON, G., and NORYMBERSKI, J. K.Novocaine in "frozen shoulder", 231Nucleus, herniation of, in intervertebral disk, 3Nuffield Foundation, grants for research, 374Nutrition and rheumatism, acute, 324

Oedema of heel in rheumatoid arthritis, 50

Oophorectomy, arthritis, rheumatoid, and, 341*ORTONA, L., 75Osteitis condensans ilii and ankylosing spondylitis, 147Osteo-arthritis and arteritis, 136

of cervical spine, neurology of, 363and Gaucher's disease, 230hydrocortisone analogues in, 297of shoulder, 159Trafuril in, 70

Osteo-arthropathy, experimental, induced by growth hormone, 346pulmonary, due to carcinoma of lung, 54

Osteophytes in spondylosis, 7OSTER, G., 361Oxygen, consumption of, and hydrobenzoic acid, 60

Pain, muscular, electromyographic studies of, 331- in spondylosis, 10Pancreas, polyarteritis nodosa in, 280Paraplegia, para-articular calcification in, 372Pare, Ambroise, 195Paul of Aegina, 194PEKANMAKI. K.: See LAINE, V. A. I., VAINIO, K. J., and PEKANMAKI,

K.Pelvis, calcinosis of, 20Pelvo-spondylitis ossificans: See Spondylitis, ankylosingPemphigus, hormone therapy in, 310Pepsin, action of, on nodules, 33Periarthritis of shoulder, 159Periodic acid-Schiff (P.A.S.), 28Personality of rheumatoid patients, 312PETERSON, R. E., 347PETrT, H., 374Pharmacopoeia, colchicum derivatives in, 195Phenylbutazone in arthritis, rheumatoid, 201-, gouty, 317in spondylitis, ankylosing, 188, 201and uric acid excretion, 318uricosuric effect of, 321

394

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INDEXPhosphotungstic acid-haemotoxylin (P.T.A.H.), 28Physiotherapy in ankylosing spondylitis, 188*PIAcENTINI, G., 75*PIERRE, R., 75PIRKIS, J., 372Pituitary-adrenal system in rheumatism, acute, 356Placenta, implantation of, in rheumatoid arthritis, 63Plasma, cortisone and hydrocortisone metabolism in, 347

post-partum, in rheumatoid arthritis, 131proteins, electrophoresis in study of, 201uric acid in, in gout, 124

Plasmocytosis in bone marrow in arthritis, rheumatoid, 328*PLISHUK, F., 167PLOTZ, C. M., *167 bis, 350POLLEY, H. F., 353, 367Polyarteritis nodosa and arthritis, rheumatoid, 136, 277Polyarthritis and arterial lesions, 278Polyvasculitis, hormone therapy in, 310POND, M. H.: 17-ketosteroid excretion in two unusual forms of

rheumatoid disease, 67*PORRO, F., 75PORTER, J. L., 164POTTER, T. A., 364Pregnancy and arthritis rheumatoid, 133Preputial glands, response to cortisone, 105*PREzIosi, P., 75Probenecid in gout, 120, 233Procaine, intra-articular, in arthritis, rheumatoid, 373

and uric acid excretion, 234Protein deficiency and rheumatism, acute, 324-, plasma, electrophoresis of, 201Proteinuria and erythrocyte sedimentation rate, 337Pseudarthrosis in ankylosing spondylitis, 188Psychosis in hormone therapy, 308Psycho-social factors in rehabilitation of chronic arthritic, 312*PUDDU, V., 75*PURKISS, J., 256*PURSER, J. A., 75

Quincy, John, 195

Radiology of Gaucher's disease, 230-of heel in arthritis rheumatoid, 44

of spondylitis, ankylosing, 188, 219Radiotherapy in ankylosing spondylitis, 188, 201RAGAN, C., 344, 361*RAMMELKAMP, C. H., 257RANTZ, L. A., 355*RAWLS, W. B., 167Reflex dystrophy, sympathetic, 159Rehabilitation of arthritic, psycho-social factors in, 312REID, H. A.: Reiter's syndrome and cortisone, 161REIDY, J. P., 74Reiter's syndrome, cortisone in, 161Remissions in arthritis, rheumatoid, 362RESEARCH:Empire Rheumatism Council, 164Hospital Reports, 252Italy: Acqui Prize, 257Nuffield Foundation Grants, 374Professorship of Rheumatology, Brazil, 71, 167World Health Organization, 253

REYNOLDS, W. E., 362Rheumatic fever: See Rheumatism, acuteRheumatism, acute, amino acids in, 324

and arteritis, 136Bicillin prophylaxis in, 358

,-, as collagen disease, 324cortisone in, 325diabetes and, 324

- diet and, 324with Gaucher's disease, 229hormone therapy in, 310hydrobenzoic acid in, 60insulin in, 325pituitary-adrenal system in, 356salicylic acid in, 60serum levels in, 212, 213

Rheumatoid arthritis: See Arthritis, rheumatoid*RICHARDSON, E. M., 75ROBERTS, J. B., 367ROBINSON, W. D., *257, 368Roman physicians, 193RoMANuS, R.: See ENGFELDT, B., ROMANUS, R., and YDfN, S.ROSENBERG, E. F., 364Ross, J. F., 365*RUDD, E., 167RUSOFF, J. H., 358Ryff, Walther Hermann, 195

SAMMAN, P. D., 74Sarcolemma, histopathology of, in Coxsackie virus infection, 35

395Sarcoplasm, histopathology of, in Coxsackie virus infection, 35SARGENT, F., 75Scapulo-costal syndrome, 160*SCHWARTZ, L. L., 167*SCHUBERT, M., 373Sciatica, 12Scleroderma and arteritis, 136-, cortisone and peripheral vessels in, 302-, hormone therapy in, 310Sclerosis, systemic, cortisone and, 303, 304Scribonius Largus, 193*ScURo, L. A., 75SELYE, H.: On the mechanism through which obstructive jaundice

influences inflammatory processes, 102Serapion Junior, 194Serum levels in rheumatism, acute, 211

urate levels and phenylbutazone, 317uric acid levels in gout, 123, 236

*StzE, S. DE, 257*SFOGLIANO, C., 75SHARP, J.: Heredo-familial vascular and articular calcification, 15SHORT, C. L., *257, 362Shoulder, "frozen", and cervical spondylosis, 10

lesions in rheumatoid arthritis, 157Side-effects, 350

*SIGNY, G., 75SIMPSON, M. E., 346SIROTA, J. H., 366Sjogren's syndrome, 17-ketosteroid excretion in, 67Skin temperature, cortisone and, 303SMITH, R. T., 368Smith-Petersen's cup arthroplasty, 188SMYTH, C. J., 367

See HUFFMAN, E. R., WILSON, G. M., SMYTH, C. J., andHILL, R.

SMUKLER, N., 354See HOLLANDER, J. L., BROWN, E. M., JR., JESSAR, R. A.,UDELL, L., SMUKLER, N., and BOWIE, M. A.

Society Italiana di Reumatologia: See Italian Society of Rheu-matology

SOCIETIES:American Rheumatism Association, 344Arthritis and Rheumatism Foundation, 257British Empire Postgraduate Medical Federation, 375British Rheumatic Association, 71Canadian Rheumatism Association, 257Chartered Society of Physiotherapy, 374Empire Rheumatism Council, 164, 166. 375European League against Rheumatism, 373Fellowship of Postgraduate Medicine, 75Heberden Society, 72, 74, 255, 256, 372, 373Italian Society of Rheumatology, 75, 257Mexican League against Rheumatism, 375New York Rheumatism Association, 167

Sodium salicylate in gout, 233*SOLOMON, W., 257Somatic pain and muscle spasm, 331Spine, biopsies of, 221

calcinosis of, 21cervical, osteo-arthritis of, 363

,deformity of, in osteitis condensans ilii, 151pathology of, 7

Spleen, response to cortisone, 105Splenectomy and Gaucher's disease, 229Spondylitis, ankylosing, and ACTH, 109-, , and arteritis, 136

cortisone in, 207gold in, 208histological studies of, 21917-ketosteroid excretion in, 67and osteitis condensans ilii, 147phenylbutazone in, 208plasma proteins in, 201radiotherapy in, 201serum levels in, 212, 216survey of, 186

in arthritis, rheumatoid, juvenile, 364Spondylosis, survey of, 2Staining of sections of nodules, 28STECHER, R. M., 256, *372STEIN, H.: See LOWMAN, E. W., MILLER, S., LEE, P. R., STEIN, H.,

KING, R., and HEALD, L.STEINBERG, C. L., 360*STEINBROCKER, 0., 167-: See NEUSTADT, D. H. GEIGER J., and STEINBROCKER, 0.STILLMAN, J. S., 364Stoerck, Anton, 195STOLLERMAN, G. H., 358STOREY, G. O., *256, 372STRANDBERG, B.: Histopathological changes in sarcilemma and

sarcoplasm in Coxsackie virus infection, 35

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396 ANNALS OF THE RHEUMATIC DISEASESStreptococcus, Group -A, prophylaxis in rheumatism, acute, by Urine, uric acid in, in gout, 123, 233

Bicillin, 358 Uricosuric agents and gout, 366haemolyticus infections in childhood, 355 Uterus amputation, arthritis, rheumatoid, and, 341

Stress, antiphlogistic effect of, 102Strumectomy: See Thyroidectomy VAINIO, K. J.: See LAINE, V. A. I., VAINIO, K. J., and HOLOPAINEN,Subluxation of joints, 19 T. E.Sulphur metabolism and arthritis, rheumatoid, 325 See LAINE, V. A. I., VAINIO, K. J., and PEKANMAKI, K.

radioactive, uptake of, and hypophysectomy, 360 Vertebrae, pathology of, 4Surgery and arthritis, rheumatoid, 341 Vessels, blood, lesions of, in rheumatic disease, 136Surugen: See Colchicum -, calcinosis of, familial 15Sydenham, Thomas, 195 Virus, Coxsackie: See Coxsackie virusSynovial fluid, physico-chemical investigation of, 362 Von Bechterew's disease: see Spondylitis, ankylosingSynovium, hydrocortisone in, 297

metabolism of adrenal cortical steroids in, 347 Walpole, Horace, 195punch biopsy of, in diagnosis. 353 WARREN, J., 361

WEST, H. F.: Purified ACTH gel Control of therapy in rheumatoidTAVERNER, D., 255 patients, 56

Muscle spasm as a cause of somatic pain, 331 * 74, 351, 352, *373TAYLOR, J. E. DUNCAN, 372 , and NEWNS, G. R.: Ankylosing spondylitis and prolongedTendinitis, 158 ACTH therapy, 109Tenosynovitis, 158 WILSON, G. M.: See HUFFMAN, E. R., WILSON, G. M., SMYTH, C. J.,Theophrastus of Eresus, 192 and HILL, R.THOMAS, L., 359 WILSON, H., *167, 347*THOMPSON, M., *74, *256, 372 *WOLF, M., 167 bis

Osteitis condensans ilii and its differentiation from ankylosing WOODMANSEY, A., 256spondylitis, 147 World Health Organization, First Report of Expert Committee on

Thoracic spine, pathology of, 12 Rheumatic Diseases, 253Thymus response to cortisone, 104 WYNGAARDEN, B., 347Thyroidectomy in arthritis, rheumatoid, 250, 341*TILLIS, H. H., 167 X-ray Therapy: See RadiotherapyTonsillectomy and arthritis, rheumatoid, 341Tophi in gout, 233 YDFN, S.: See ENGFELDT, B., ROMANUS, R., and YDEN, S.*TOSTI, E., 75 *YEOMAN, W., 374Toxicity in hormone therapy, 308 YO, T. F., * 167, 366

in hydrocortisone therapy, 295Toxicology of colchicine, 197 *ZACCO, M., 75Trafuril, 70 ZIFF, M., *167 bis, 347, 352Trauma, surgical, arthritis, rheumatoid, and, 341 Zone electrophoresis in study of plasma proteins, 201TREW, J. A.: See HUNT, T. E., and TREW, J. A.Trypsin, action of, on nodules, 33 2 : 6 dihydrobenzoic acid, 61TWEED, J. M., 164 9-(x-chloro hydrocortisone, 297, 354

9-cx-fluoro hydrocortisone acetate, 291, 299, 348UDELL, L., 354 1 1-oxy-17-ketosteroid, 67

See HOLLANDER, J. L., BROWN, E. M., JR., JESSAR, R. A., 17-ketogenic steroids, 56UDELL, L., SMUKLER, N., and BOWIE, M. A. in spondylitis, ankylosing, 109

Urine, assay of corticosteroids in, 56, 59 17-ketosteroids developed from corticosteroids, 56excretion of 17-ketosteroids in, in ankylosing spondylitis, 67 urinary excretion of, 109, 291in Sjogren's syndrome, 67 in Sjogren's syndrome, 67urate excretion in, and phenylbutazone, 317 in spondylitis, ankylosing, 67, 109

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INDEX TO SUBJECTS OF ARTICLESABSTRACTED

* indicates that only the title of the article is given

Acid, acetylsalicylic, in arthritis, rheumatoid, 79ascorbic, in arthritis, rheumatoid, 80

depletion by ACTH with polyphloretin phosphate, 267mephenesin and salicylamide, 381metabolism, ACTH and, 268in rheumatism, acute, 379*

diacetylpyrocatchol carboxylic, with cortisone, *276glycyrrhetinic, and cortisone, 386lactic, in osteo-arthritis, 173lysergic, diethylamide in arthritis, rheumatoid, 80p-acetylaminosalicylic, in rheumatism, acute, 259p-aminobenzoic, in arthritis, rheumatoid, 261

and cortisone metabolism in liver, 272pyruvic, in blood, steroid therapy and, *276salicylic, action of, *87

, and hormone therapy, *264ACTH and adrenal response, 269

and steroid levels in plasma, 269and - weight, 98and allergy, 182anaphylactoid reaction, 387and antibody production, 93in arthritis, rheumatoid, 171, 172in arthrosis, *390and ascorbic acid metabolism, 268in asthma, 387and blood, 97, 269, 272and -, pyruvic acid, *276and bone marrow, 97 bisand burns, 275and capillary resistance, *275and carditis, rheumatic, 76in children, *171in chorea minor, 170in dermatomyositis, 174and diabetic mothers, infants of, 272and eosinophil count, 98, * 171, 179, 266in exophthalmos, *99in eye disease, 99 quintetin surgery, 182gastro-intestinal side-effects and, *276and Hamman-Rich syndrome, 274and herpes zoster, *99and keloids, 270and leucocytes, 98in lipoid nephrosis, 388and liver, 94in lupus erythematosus, 85, 271, 386and mental function, 274in nephrosis, 182in neuroretinitis, 99in non-rheumatic conditions, 183and orbital oedema, *99in osteo-arthritis, *84in palindromic rheumatism, *382and p-aminobenzoic acid in arthritis, rheumatoid, 80with polyphloretin phosphate, 181, 267and psychiatric risk, 275in ragweed allergy, 182in Reiter's syndrome, 180in rheumatism, acute, 376, *379in shoulder, painful, 265in Still's disease, 82after surgery for arachnoiditis of optic chiasma, 182in tetanus, 388thymus involution test for, 98 bisin tuberculosis, pulmonary, 389 bisand vitamin-C metabolism, 94withdrawal, 274

Adrenal atrophy due to cortisone, prevented by testosterone, 93cortex activity, assessment of, by assay of urinary 17-keto-steroids, 90-and colchicine, 97corticoids and concept of rheumatism, *390gland surgery in Cushing's syndrome, 95histology of, 183

397

Adrenal hyperplasia, cortisone in, 387response to ACTH, 269

Adrenaline and burns, 275cream, test of, 100

Adrenalectomy, urinary steroid excretion after, 179Adrenocortical function and epinephrine, 94

in infants of diabetic mothers, 272in rheumatism, acute, 76

, suppression of, by cortisone, 184insufficiency, cortisone in, 269

post-operative, after cortisone treatment, 96specific water diuresis test in, 95

lipids in experimental pyrexia, *180-steroids and eosinopenia, 183

syndrome, congenital, cortisone and, 269Adrenocorticotrophic activity, increase of, 96Aetiology of rheumatism, 265Agglutination, sheep cell, *83, *180 bis, *266, *385Agranulocytosis, fatal, due to phenylbutazone, *87Albers-Schonberg disease, radiology of, * 178Allergy, bacterial, and protein metabolism, cortisone in, 267

, cortisone in, 99 bisAnaemia of arthritis, rheumatoid, 82Angioneurotic oedema of orbit, ACTH in, *99Ankylosing spondylitis: See Spondylitis, ankylosingAntibiotics, cortisone and, 267Antibody production, experimental, ACTH and, 93

- ,- 1,cortisone and, 93Antistreptolysin titre in children, *91Amidopyrin gentisate in rheumatism, *87 bis, 380p-Aminobenzoate in arthritis, rheumatoid, 79p-Aminobenzoic acid with ACTH in arthritis, rheumatoid, 80

and cortisone metabolism in liver, 272Aorta, rheumatic stenosis of, commissurotomy for, 376Appendicular syndrome and rheumatism, *100Arthritis, chronic, in children, *87

,pathogenesis of hyperfibrinogenaemia in, *87phenylbutazone in, *379therapy of, *87, 174

experimental, cortisone in, *99and diethylstilboestrol in, *276

,gouty, *89 bis, phenylbutazone in, *264

rheumatoid, acetylsalicylic acid in, 79ACTH in, 171, 172

and p-aminobenzoic acid in, 80adrenal hormones in, *87in aged, 172agglutination in, *91, *266, *385anaemia of, 82anthropological data, *83artisone in, *83

- ascorbic acid in, 80, *379Atebrin in, 81aurothioglycanide (Lauron) in, 79B-tetrahydronaphthylamine in, 81and blood, *261and sugar, cortisone in, *385cardiac lesions in, *83, *379chloro-amines in, *87citrate iontophoresis in, 378codeine in, 261cortisone in, 171, 261 bis, 378, *390

and nodules in, 266with phenylbutazone in, *83

diagnosis of, *83electromyography in, *83genetics of, 82gold in, *261glucose-l-phosphate in, 80hand, rehabilitation of, in, 82and heart lesions, *83, *379hormone therapy and urinary steroid excretion in, 79

,hyaluronidase inhibition in, 174hydrocortisone, intra-articular, in, 92 ter, *261hypoglycaemia in, 80

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398 ANNALS OF THE RHEUMATIC DISEASESArthritis, rheumatoid, in industrial medicine, *83 Carditis, rheumatic, hormone therapy in children, 168 bis

iron in, 172 Cartilage, articular, in osteo-arthritis, 173laboratory tests for, *91 histology of, *180and liver function, *91, 265, *267 polarized light studies of, 385lysergic acid diethylamide in, 80 Chemotherapy in arthritis, rheumatoid, 172musculo skeletal function in, *262 Children, antistreptolysin titre in, *91neurovegetative inquiries in, *262 , arthritis, chronic, in, *87nitrogen mustard in, *379 carditis, rheumatic, in, hormone therapy, 168 bisp-aminobenzoic acid in, 261 , salicylate therapy, 168

benzoate in, 79 and collagen disease, serum complement in, 89phenylbutazone in, 86, 261, *264 dermatomyositis in, 174placental tissue implantation in, 378 of diabetic mothers, 272polyvalent autovaccines in, *261 , disks, protruded lumbar intervertebral, in, 382procaine in, 172 , eczema in, cortisone and, 388prognosis of, *83 and gantrisin tolerance in rheumatism, acute, *78pulmonary lesions in, 377, *379 and hyaluronidase-haemoglobin/dispersion test in rheumatism,radiology of, *262 *385

- of chest in coal miners, 260 neplirotic, steroid therapy in, 182- of sacro-iliac joint, 173 ocular symptoms in, and rheumatism, 100

Review of 10 years' literature (Tenth Rheumatism and rheumatism, acute, ACTH in, *171, *379Review, Part 1), *178 ,-, diagnosis of, 90

"salimeph-C" in, 381 , -, in infancy, *171serum agglutination in, *91 , --, prevention of, *260-c copper in, 179 , psychology of, in, *78and

iron in, 179 , treatment of, 76, 77and skin, neurovegetative reactivity of, *379 Chloramphenicol in Reiter's syndrome, *177and thickness of, in hands, *379 Chloro-amines in arthritis, rheumatoid, *87and spinal osteo-arthritis, *382 Chloroquine sulphate in lupus erythematosus, 262splenectomy in, 81 Chorea, acute, 78syndromes of, 377 minor, ACTH in, 170systemic lesions in, 377 -, cortisone in, 170thiosemicarbazone, 79 Chrysotherapy: See Goldtrypsin in, *261 Circulation in osteitis deformans, 175vaccine with chemotherapy in, 172 skin and peripheral, in rheumatism, 276vascular factors in, *379 Citrate iontophoresis in arthritis, rheumatoid, 378vascularity of subcutaneous nodes in, 91 Coalminers, chest radiology and arthritis, rheumatoid, in, 260

Arthrography of knee, 177 bis - rheumatism in, *178of shoulder, * 178 Codeine and cortisone in arthritis, rheumatoid, 261

Arthropathy, pararheumatic, 85 Cogan's syndrome, *88in Reiter's syndrome, *88 Colchicine and adrenal cortex, 97

Arthrosis, ACTH in, *390 and pituitary gland. 97cortisone in, *390 intravenous, in acute gout, 382of shoulder, 172 Colchicum autumnale in joint disease, *382

Artisone in arthritis, rheumatoid, *83 Colinet and Caplan's syndrome, *178Aschoff bodies in auricular appendages and rheumatic activity, 78 Collagen: chondroitin-sulphate ratio in osteo-arthritis, 173

in diagnosis of rheumatism, acute, 169 disease in children, serum complement in, 89Ascitic fluid, 17-hydroxycorticosterone in, 184 and pulmonary lesions, 381Aspirin in rheumatism, acute, 376 fibrillar structure of cartilage, 385Assessment of response of treatment, * 178 Commissurotomy, mitral, and rheumatism, acute, 169Asthma, ACTH in, 387 in rheumatic aortic stenosis, 376

bronchial, chloro-amines in, *87 , rheumatic manifestations provoked by, 390epinephrine and, 94 Compound F: See Hydrocortisone

Atebrin: See Mepacrine Copper, serum, in arthritis, rheumatoid, 179Aureomycin in erythema exudativum multiforme, *88 Corticoids, urinary, in infants of diabetic mothers, 272

in rheumatism, acute, 77, 170 Corticotrophin: See ACTHAurothioglycanide (Lauron) in arthritis, rheumatoid, 79 Cortisone, adrenal atrophy due to, prevented by testosterone, 93"Aurubin", 378 - and capillary histology, 183Auscultation of joints, *88 and hyperplasia, 387Autovaccines, polyvalent, in arthritis, rheumatoid, *261 and system, 269 bis

- and adrenocortical insufficiency, post-operative, 96Baastrup's disease: See Pseud-arthrosis, interspinous and allergy, ocular, 99Backache, benign, *382 and antibiotics, 267Bacteriology, * 180 and antibody production, 93Ballistocardiogram in rheumatism, acute, 259 antiphlogistic action of, *390Basedowian exophthalmos, ACTH in, *99 in arthritis, rheumatoid, 171, 261, *390Bechterew's disease: See Spondylitis, ankylosing in arthrosis, *390B-tetrahydronaphthylamine in arthritis, rheumatoid, 81 in asthma, 273Biopsy, liver, in arthritis, rheumatoid, 265 and blood, 97, *385Blood disorders, ACTH and, 272 - in- disorders, 272

cortisone and, 272 and- pyruvic acid, *276phenylbutazone and, 87 and bone marrow, 97 bis

eosinophils and ACTH, 266 in bronchitis, 273- and hormone therapy, 97 bis - and capillary permeability, 385

peripheral, ACTH and eosinophils in, 179 in carditis, rheumatic, 76sugar and cortisone, *385 - in chorea minor, 170

- vessels in arthritis, rheumatoid, *379 and codeine in arthritis, rheumatoid, 261Bone, histology of, *180 - in dermatitis, contact, 181- marrow after hormone therapy, 97 bis in dermatomyositis, 174Bouillaud's disease, *180 and diacetylpyrocatchol carboxylic acid, *276Brucellosis and rheumatism, *382 and diethylstilboestrol in arthritis, experimental, *276Burns, ACTH and, 275 dosage, 171-, adrenaline and, 275 in eczema, infantile, 182, 388

-, adrenocortical function and, 275 and eosinophil count, 98Bursitis, pathogenesis of, 384 and erythrocyte sedimentation rate in rheumatism, acute, *171Butazolidin: See Phenylbutazone in eye disease, 99 quinter, 272, 390 ter

- and gastro-intestinal side-effects, *276Capillary permeability and cortisone, 385 and glycyrrhetinic acid, 386- resistance and steroid therapy, *275 and granulation tissue histology, 94Carditis, rheumatic, corticotrophin in, 76 and Hamman-Rich syndrome, 274

cortisone in, 76 in hay fever, 99disturbances of conduction, *78 in herpes zoster, 272lesions of, *83, 169, *171, *379 in hypopituitarism, 386

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INDEXCortisone in iridocyclitis, 99

and keloids, 270and leucocytes, 98and liver, 94, 272in lupus erythematosus, 85, 271, 386and macrophages, 98and metabolic response to injury, 96metabolism in liver tissue, p-aminobenzoic acid and, 272in neuroretinitis, 99and nodules, subcutaneous, 266in non-rheumatic conditions, 183in pemphigus, 271and phenylbutazone, *83, 380and pituitary histology, 183and somatrophin, 268plasma mucoproteins and protein sugar, *385in pneumoconiosis, 273and polyarthritis, experimental, *99prolonged therapy, *99

in arthritis, rheumatoid, 378' , in spondylitis, Marie-Strumpell, 84and protein metabolism in bacterial allergy, 267in pseudohermaphroditism, 387psychiatric risk and, 275, *276and reticuloendothelial phagocytosis of streptococci, 267and retrobulbar neuritis, *99in rheumatism, acute, 376

-in sarcoidosis, 91in shoulder, painful, 264, 265,side-effects of, *276in Sjogren's syndrome, *99, *275

--and sodium compounds, 270in spondylitis with iridocyclitis, *99in Still's disease, 82and synovial fluid, *275, *276

-and testicular development, 387and testosterone, 93topical, in contact dermatitis, 181in tuberculosis, experimental pulmonary, 389 bis

--in , ocular, 390and tumours, experimental, 270

--and vitamin-C metabolism, 94withdrawal, 274, *275- in rheumatism, acute, * 171acetate after adrenalectomy, 179

- in arthritis, rheumatoid, 261C-reactive serum protein and rheumatism, acute, 258Creatinine therapy, 378Cushing's syndrome, adrenal gland surgery in, 95

Deaths after steroid withdrawal, 274Dental sepsis and rheumatism, *100Dermatitis, topical cortisone in, 181Dermatomyositis in children, hormone therapy, 174Diabetes in infants of diabetic mothers, 272Diagnosis, differential, in rheumatism, 276Dibenylethylenediamine-dipenicillin in prophylaxis of rheumatism,

acute, *377Diethylstilboestrol and cortisone in experimental arthritis, *276Disk syndrome, 178, *264 bis

intervertebral, hernia of, *178lumbar, *88

-' , protruded, in children, 382pathology of, *264

Diuresis test in adrenocortical insufficiency, 95Dupuytren's contracture, pathology of, 179- -, radiotherapy in, 176Dupuytren, reputation of, 99Dysarthria, developmental, 263Dysphagia in spondylosis, cervical, 178

Eczema, cortisone in, 182-, infantile, cortisone in, 388Effusion in knee joint, *262Eggs and rheumatism, acute, 259Electrolytic metabolism in gout, 178Electromyography in diagnosis of arthritis, rheumatoid, *83Electrophoresis of blood proteins in rheumatism, acute, 169Eosinopenia, glucocorticosteroids, reticulo-endothelial system and,

266steroids and adrenomedullary hormones and, 183

Eosinophils in blood and marrow, ACTH and, 179, 266count, ACTH and, 98

,cortisone and, 98Epicondylitis, * 178Epinephrine and adrenal cortical function, 94- tolerance in asthma, 94Erythema exudativum multiforme, *88 bis

and virus infections, 175Erythrocyte sedimentation rate and plasma viscosity, *385

in synovium, *180

399Excretion, urinary steroid and hormone therapy in arthritis,

rheumatoid, 79Eye disease, ACTH in, 99

cortisone in, 99 quinter, 272, 390 ter,hydrocortisone in, 273

lesions in gout, 88 bissymptoms in children with rheumatism, *83, 100

Felty's syndrome, 81Femur, radiology of head of, *382

, vascular anatomy of head of, 84Fibrositis, *265

Ganglion, gasserian, procaine infiltration of, in arthritis, rheumatoid,172

Gantrisin, tolerance by children in rheumatism, acute, *78Gaucher's disease, haematology of, 384Genetics splenectomy in, 384Genetics of arthritis, rheumatoid, 82Geriatrics, radiology of femoral head in, *382

rheumatism acute, in older patients, 376Gland, pituitary, and colchicine, 97Glucocorticosteroids, reticulo-endothelium and eosinopenic reaction

to, 266Glucose-l-phosphate in arthritis, rheumatoid, 80Glycyrrhizin after adrenalectomy, 179Gold therapy, 378, *379

in arthritis, rheumatoid, *261in palindromic rheumatism, *382

Gout, colchicine, intravenous, in, 382eye lesions in, 88 bisin men, *264metabolic studies of electrolytes, 178

,primary and secondary, 383phenylbutazone in, *89, 264 bis, 383sodium salicylate in, 88, *383treatment, 89 quater

Granulation tissue, histology of, tissue and cortisone therapycompared, 94

Granulocytopenia after phenylbutazone, *382Granuloma, rheumatic, pathogenesis of, 89Group-A B-haemolytic streptococcus allergy and arthritis, rheuma-

toid, 259GT50: See Vitamin D2Haematology of arthritis, rheumatoid, *261- of Gaucher's disease, 384Hamman-Rich syndrome, 274Hand, arthritis, rheumatoid, of, 378

rehabilitation in arthritis, rheumatoid, 82skinfold thickness of, in arthritis, rheumatoid, *379

Hay fever, oral cortisone in, 99Heart disease: See CarditisHeparin and hyperfibrinogenaemia, *87- in rheumatism, acute, 258Herpes zoster, cortisone in, 272

- ophthalmicus, ACTH in, *99Hip, arthritis of, intra-articular injections in, *173

, congenital dislocation of, 83derangements in cerebral palsy, 83,osteo-arthritis of, *262

-, pseudo-polyarthritis of, 265Histology of adrenal and pituitary, cortisone and, 183

of granulation tissue, 94Hormone, adrenomedullary, and eosinopenia, 183

therapy in carditis, rheumatic, 168 bisminimal doses, in hyaluronidase, *264in rheumatism, acute, *260

-- in rheumatology, *99 bis- and salicylic acid, *264

- - and spa treatment, * 100and urinary steroid excretion in arthritis, rheumatoid, 79

Hyaluronidase-haemoglobin dispersion test, *385-inhibition in arthritis, rheumatoid, 174

in rheumatic disease, *382Hydrocortisone, action of, 268, *390

in eye diseases, 273, intra-articular, 92 ter, 180, *264, 271injections in sarcoidosis, 91in rheumatology, 91, *99 bisoral, in arthritis, rheumatoid, *261in osteo-arthritis, *84in shoulder, painful, 264

--in soft-tissue lesions, 181acetate, intra-articular, *275 bis, *276, 385- in periarthritis of shoulder, 270

Hydrocortone: See HydrocortisoneHypercortisonism and withdrawal syndrome, *275Hyperfibrinogenaemia, pathogenesis of, in arthritis, rheumatoid, *87-, placental thromboplastin and, *87Hypoglycaemia in arthritis, rheumatoid, 80Hypopituitarism, cortisone in, 386

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400 ANNALS OF THE RHEUMATIC DISEASESIndustry, arthritis, rheumatoid, and, *83 Osteo-arthritis, hydrocortisone in, *84Injury, metabolic response to, and cortisone, 96 of knee, *84, *262lontophoresis, citrate, in arthritis, rheumatoid, 378 - lactic acid in, 173"Irgapyrin", toxicity of, *177 bis - phenylbutazone in, 84Iritis, gouty, 88 radiotherapy in, *173Iron, intravenous, in arthritis, rheumatoid, 172 Osteogenesis imperfecta, histology of, *180-, serum, in arthritis, rheumatoid, 179 Osteoporosis, senile, of spine, 176

Joint, auscultation of, *88 Paget's disease: See Osteitis deformanssternoclavicular in rheumatism, 384 Pain and cervical spondylosis, *88, *382

Palindromic rheumatism, gold and ACTH in, *382Keloids, ACTH in, 270 Palsy, cerebral, and hip derangements, 83

cortisone in, 270 PAS in rheumatism, acute, *377Keratitis, non-syphilitic interstitial, and deafness with peri-arteritis in tuberculosis, pulmonary, 389

nodosa, *88 Pemphigus, oral cortisone in, 271Ketonic fractions in urinary steroid excretion, 79 Penicillin in rheumatism, acute, 76Knee, arthrography of, 177 Periarteritis nodosa with Cogan's syndrome, *88

cartilage studied with polarized light, 385 - and rheumatism, *88effusion in osteo-arthritis, *262 Periarthritis, *178jerk, loss of, in sciatica, * 178 , humero-scapular, 265, 270osteo-arthritis of, *84 Phagocytosis of streptococci, effect of cortisone on reticuloendo-tomography of, 177 thelial, 267

Phenylbutazone, *87, 380, *381 bisLaboratory studies of hormone therapy, *99 in arthritis, rheumatoid, 86, 261, *264, 379Lauron: See Aurothioglycanide with cortisone, *83Leucocytes, phagocytic activities of, cortisone and, 98 in gout, *89, *264, 264 bis, 383

ACTH and, 98 in joint disease, *178Leukergy in locomotor disturbances, *100 - in osteo-arthritis, 84Liver biopsy in arthritis, rheumatoid, 265 parenteral, 263-, cortisone metabolism in, and p-aminobenzoic acid, 272 in spondylitis, *264-- function in arthritis, rheumatoid, *91 bis, *267 in Stevens-Johnson syndrome and granulocytopenia, *382

-- in rheumatism, acute, *83 toxicity of, 87 terweight and composition of, and ACTH, 94 and blood level, 263

and cortisone, 94 Phospholipid serum, in rheumatism, acute, 259Locomotor lesions and leukergy, *100 Phosphorus, radioactive, in tissue analysis in rheumatism, acute, *83Lung lesions in arthritis, rheumatoid, 377, *379 Physiotherapy, value of, 100- in collagen disease, 381 Pirisal: See Amidopyrine gentisateLupus erythematosus, ACTH in, 85, 271, 386 Pituitary, histology of, 183

acute, nitrogen mustard in, 86 therapy in rheumatology, *99chloroquine sulphate in, 262 Placental tissue implantation in arthritis, rheumatoid, 378cortisone in, 85. 271, 386 Plasma adrenal steroid levels, ACTH and, 269disseminated, natural history of, 85 bis mucoproteins and protein sugar, effect of cortisone, *385mepacrine in, 174 - proteins, electrophoresis of, in rheumatism, acute, 169ocular lesions, 381 - viscosity and erythrocyte sedimentation rate, *385splenectomy in, 262 Pneumoconiosis and arthritis, rheumatoid, 260triethylene melamine in, 86 Polyarthritis, microbe therapy of, *382

Lymphadenitis abdominal, *382 in rubella, *382Polyphloretin phosphate with ACTH, ascorbic acid depletion by, 267

Macrophages, phagocytic activities of, ACTH and, 98 Polysaccharide, group-A precipitin in streptococcosis and rheu---,-,1 cortisone and, 98 matism, acute, 90Manipulation of shoulder, 265 Procaine, infiltration of nerves with, in arthritis, rheumatoid, 172Marie-Strumpell's disease: See Spondylitis, 84 Protein, C-reactive, in serum in rheumatoid, arthritis, 258Marrow, ACTH and eosinophils in, 179, 266 metabolism and bacterial allergy, cortisone in, 267- histology in osteitis deformans, 180, *180 plasma and serum, electrophoresis in rheumatism, acute, 169Massage, value of, 100 Prothrombin time in rheumatism, acute, 383Mental function, ACTH and, 274, 275 Pseudo-arthrosis, interspinous, *264

, cortisone and, 275, *276 Pseudohermaphroditism, cortisone in, 387Mepacrine in arthritis, rheumatoid, 81 Pseudo-polyarthritis of hip and shoulder, 265

in lupus erythematosus, 174 Psychogenic rheumatism, *382 bisMephenesin, salicylamide and ascorbic acid, 381 Psychology of children with rheumatism, acute, *78Metabolism of ascorbic acid, ACTH in, 269 Pyrexia, experimental, adrenocortical lipids in, * 180

of cortisone in liver, p-aminobenzoic acid and, 272of electrolytes in gout, 178 Radiology of Albers-Schonberg Disease, *178of protein and cortisone in bacterial allergy, 267 of arthritis, rheumatoid, *262response of, to injury, 96 - of chest in coal miners and arthritis, rheumatoid, 260and salicylate, 381 of femoral head, *382

Microbe therapy of polyarthritis, *382 of osteitis, pyogenic, 175Muscle spasm, stigmonene bromide in, 263 of osteoporosis of spine, 176Musculo-skeletal function in arthritis, rheumatoid, *262 of sacro-iliac joint, 173Myelopathy and cervical osteo-arthritis, *264 of sarcoma, osteoblastic osteogenic, 176Myocarditis in rheumatism, acute, 168 Radiotherapy in Dupuytren's contracture, 176

in osteo-arthritis, *173Nephrosis, steroid therapy in, 182 bis (deep x-ray) in spondylitis, 379

lipoid, ACTH in, 388 Ragweed-allergy, ACTH in, 182Nerves, splanchnic, procaine infiltration of in arthritis, rheumatoid, Rehabilitation of hand in arthritis, rheumatoid, 82

172 Reiter's syndrome, *88 bisNeuroretinitis, cortisone in 99 - ACTH in, 180Neurovegetative inquiries in arthritis, rheumatoid, *262 - chloramphenicol in, *177Nitrogen mustard in rheumatism, acute, *379 Research in rheumatism, *382

in lupus erythematosus, 86 Reticuloendothelial phagocytosis of streptococci, cortisone and, 267Node, subcutaneous, vascularity of, 91 Reticuloendothelium and eosinopenic reaction to glucocortico-Nodules, subcutaneous, cortisone and, 266 steroids, 266

Retrobulbar neuritis, cortisone in, *99Osteitis deformans, bone marrow histology in, 180 Rheumatic fever: See Rheumatism, acute

cardiac output in, 175 Rheumatism, acute, p-acetylaminosalicylic acid in, 259peripheral circulation on, 175 , ACTH in, 376, 379

pyogenic, radiology of, 175 ,-, adrenocortical function in, 76Osteo-arthritis, 83, 172, 173, *173 bis, *262 bis in the aged, 376

ACTH in, *84 , agglutination in, *83cervical, myelopathy and, *264 , allergy in, 259

- , collagen changes in cartilage, 173 , aspirin in, 376of hip, *173, *262 , , aureomycin in, 77, 170

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INDEXRheumatism, acute, in children, ACTH and, * 171, *379

comparative therapy, 376cortisone in, 376

withdrawal, *171C-reactive serum protein in, 258diagnosis, 90, *180and eggs in diet, 259in Egypt, * 171electrophoresis of blood proteins, 169

*7 erythrocyte sedimentation rate and hormone therapy in,*171follow-up study of, 260gantrisin in, *78

-, Group-A polysaccharide precipitin reactions in, 90heart conduction disturbance in, *78heparin in, 258hormone therapy in, *260

, in infancy, *171liver function in, *83and myocarditis, non-specific, 168PAS in, *377pathogenesis of, *260penicillin in, 76

- , prevention of, in children, *78, 170, *171 bis, *260, *377prothrombin time in, 383and psychological reactions in children, *78reactivation after mitral commissurotomy, 169serum antistreptolysin-levels in diagnosis of, 90- diphenylamine reaction in, 77

-, phospholipid, 259sodium salicylate in, 77

and PAS in, *377sulphonamides in, 76tissue analysis with radioactive phosphorus, *83

classification of, *100chronic, serology of, *91

Rheumatoid arthritis: See Arthritis, rheumatoidRubella, polyarthritis in, *382Rubidium-gold-creatinine-gold in rheumatic disease, 378

Sacro-iliac joint, radiology of, 173Salicylamide with mephenesin and ascorbic acid, 381Salicylate in carditis, rheumatic, in children, 168

and metabolism, 381percutaneous, experimental, *382

"Salimeph-C" in arthritis, 381Sarcoma, osteoblastic osteogenic, 176Sarcoidosis, hormone injections into skin lesions, 91

and neuroretinitis, hormone therapy in, 99Sciatica and dilatation of epidural veins, *88

traction in, *178loss of knee jerk in, *178

Scleroderma, 86Serology of chronic rheumatism, *91Serum agglutination in arthritis, rheumatoid, *91

antistreptolysin-O, levels in diagnosis of rheumatism, acute, 90complement in children with collagen disease, 89C-reactive protein in, and rheumatism, acute, 258diphenylamine in rheumatism, acute, 77iron and copper in arthritis, rheumatoid, 179phospholipid and rheumatism, acute, 259

--proteins, electrophoresis of, in rheumatism, acute, 169Sex hormones in rheumatology, *100Shoulder, arthrography of, *178

arthrosis of, 172checkrein, 265"frozen", 265painful, cortisone in, 264periarthritis of, hydrocortisone acetate in, 270pseudo-polyarthritis of, 265

Silicosis, pulmonary, and rheumatism, *178Sjogren's syndrome, cortisone in, *99, *275Skin, neurovegetative reactivity of, in arthritis, rheumatoid, *379

in spondylitis, ankylosing, *379test with "Trafuril", 86thickness of, in hand in arthritis, rheumatoid, *379

Sodium diacetyl pyrocatechol carboxylate, and pyrocatecholcarboxylate, synergism with cortisone, 270salicylate, 92

and cortisone, * 178in gout, 88, *383

- in rheumatism, acute, 77, *377Somatrophin, pituitary, in infections favoured by overdosage of

cortisone, 268Spa treatment and hormone therapy, *100Splenectomy in arthritis, rheumatoid, 81

in Gaucher's disease, 384in lupus erythematosus, 262

Splenomegaly, 384Spine, senile osteoporosis of, 176

401Spondylitis, ankylosing, diagnosis, *379

, ,late forms of, *262periarticular soft-tissue changes in, *174

, skin in, *379and tuberculosis, pulmonary, *262

cervical, pain with, *88cortisone in, 84with iridocyclitis, cortisone in, 99phenylbutazone in, *264radiology of, 173radiotherapy in, 379

Spondylosis, cervical, dysphagia and, 178, pain and, *382

hyperostotica, 85Stenosis, mitral, Aschoff bodies in diagnosis, 78

and rheumatism, acute, 169Steroid content of ascitic fluid, 184

therapy, *276urinary excretion of, after adrenalectomy, 179

in arthritis, rheumatoid, and hormone therapy, 79Still's disease, 172- , hormone therapy in, 82

ocular symptoms in, *83Stevens-Johnson syndrome, *88 ter

phenylbutazone, *382Stigmonene bromide and muscular spasm, 263Streptococcal infections and rheumatism, acute, *171Streptococci, cortisone and reticuloendothelial phagocytosis of, 267Streptococcosis, Group-A polysaccharide precipitin reactions in, 90Streptomycin in pulmonary tuberculosis, 389 terStyloiditis, *178Succinate-salicylate in arthritis, *178Sulphonamides in rheumatism, acute, 76Surgery in rheumatoid heart conditions, 376Sydenham, Thomas, 276Synovial membrane permeability, *382Synovium, erythrocyte sedimentation rate in, *180

cortisone and, *276hydrocortisone and, *276

Talalgia, study of, *264Tetanus, ACTH in, 388Testicle development and cortisone, 387Testosterone in prevention of adrenal atrophy due to cortisone, 93Thiosemicarbazone in arthritis, rheumatoid, 79Thromboplastin, placental, and hyperfibrinogenaemia, *87Thymus involution test for ACTH, 98 bisTissue analysis by radioactive phosphorus, *83Tissue, connective, clinical study of, 89

therapy and histology of granulation tissue, 94Tomography of knee, 177Tophus, conjunctival, in gout, 88Toxicity of "Irgapyrin", *177 bis

of phenylbutazone, 87 ter- and blood level, 263

Toxin, heparinoid, and hyperfibrinogenaemia, *87"Trafuril" skin test in rheumatic diseases, 86Triethylene melamine in lupus erythematosis, 86Trochanteritis, *382Trypsin in arthritis, rheumatoid, *261Tuberculosis, ocular, cortisone in, 390

pulmonary, ACTH in, 389 bischemotherapy in, 389 bisexperimental, ACTH in, 389

streptomycin in, 389 biscortisone, 389

and spondylitis, ankylosing, *262Tumours, experimental, cortisone and, 270

Ulcer, gastric, due to phenylbutazone, *87Urine, assay of 17-ketogenic steroids in, in assessing adrenocortical

activity, 90corticoid excretion in, as test of adrenocortical function ininfants of diabetic mothers, 272steroid excretion in hormone therapy, 79

Vaccine treatment in arthritis, rheumatoid, 172Vein, epidural, in sciatica, *88Vitamin B12 in rheumatism, 276Vitamin-C metabolism, ACTH and, 94

cortisone and, 94D2 in chronic joint disease, *87

Waaler-Rose reaction, *267, *385

17-ketogenic steroids, urinary, assay of, in assessing adrenocorticalactivity, 90

17-ketosteroids after adrenalectomy, 179

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INDEX TO AUTHORS OF ARTICLESABSTRACTED

* indicates that only the title of a paper or article is given

Aber, G. M., 183Abrams, W. B., 259Adams, W. S., 94*Ahringsmann, H., 265*Alameri, E., 180Albertini, A. von, 89

*Alegre Marcet, C., 276*Al6s Reinlein, J. M., 385*Alexander, R., 266Alfonso, G., 182

*Alyea, W. S., 261*Amil, M., 84Anderson, A. B., 273Anderson, A. E., 274

*Andersson, E., 84*Andreini, A., 267Andrews, G. A., 179*Antoniewicz, E., 171Archimbaud, J., 177Arlet, J., 262, *382

*Armstrong, J. R., 88*Arnold, R., 178

*Badin, J., 385Bagnall, A. W., 84, 99Baguena, J., 93BAguena, R., 93Bailey, C. P., 376Baker, F., 82Ball, K., 387

*Ballabio, C. B., 171*Barbaso, E., 262*Barcelo, H., 382Barcel6, P., *89 bis, *264

*Barcel6 Torrent, P., 276Barritt, A. S., 261Bartfeld, H., 382Baserga, R., 270Bassett, S. H., 178Batterman, R. C., 79Bauer, F., 178

*Bauer, J., 264Bauer, W., 171Bayles, T. B., 86Bayliss, R. I. S., 269Bayrd, E. D., 384Beerman, H., 91Beigelman, P. M., 86Bennett, G. A., 266Bennett, W. A., 96, 183Berdier. A., 168Bergin, J. H. E., 176Berkowitz, S., 385Bertolani, F., 259Bevans, M., 377

*Bianchi, C., 382*Bickel, G., 99*Birenbaum, A., 88Bjork-Lund, S. I., 272*Blanch Terradas, F., 172Bland, M. N., 94Bland, W. H., 94*Bloch-Michel, H., 178Bdhmig, R., 384Boni, A., 92Boistesselin, R. du, 94Boland, E. W., *178, *261Bolton, H. E., 376Bombelli, R., 97Bonamour, G., 88Bond, W. H., 86*Bonduelle, M., 264Bonnet, I., 83Bonnet, P., 83

*Bonniot, R., 264Booij, C. J., 273

*Bosch Olives, V., 88Bouissou, H., 168Bourel, M., 92, *99Bouvrain, Y., 390*Bovo, G., 78Boyne, A. W., 96Brailsford, J. F., *173, 262

*Brazelton, T. B., 78Brendstrup, P., 179Brodie, B. B., 380Bronstein, J., 385Brown, B., 383Brown, E. M., *264, 271Bruck, E., 263*Brusch, C. A., 178Brux, J. de, 94Buechner, H. A., 274

*Bulgarelli, R., 377Bunim, J. J., 91, *178, *382Burns, J. J., 380

*Busch, J., 173*Butka, K., 100

Cadman, E. F. B., 85Callahan, A., 99*Cambier, J., 99Campbell, R. M., 96*Camdiani, G., 88Caplan, A., 260Capra, R., 173, 270Cara, J., 387

*Carcassi, U., *91Cartesegna, F., *180, *379*Caruso, A. C., 379Casademont, M., *264, *276

*Castagnoli, M., 178*Cerimele, E., 87 bisCertonciny, A., 265Chandler, G. N., 183Chaouat, Y., 172Cheli, E., 388Chenkin, T., 380Chesley, G. L., 259

*Chevallier, J., 99*Chiorboli, E., 379Christie, G. S., 377Clark, E. J., 376Clark, W. S., 171Clawson, B. J., 267Clayton, B. E., 268

*Clerens, J., 178Coburn, A. F., 77Cochran, J. B., 381Cochrane, A. L., 260Cochrane, T., 174, 262Coers, R. J., 273Cohen, H., 85, 96Cohen, J., 174*Cohen, M., 264Colombi, C., 390

*Conestabile, E., 87Conrad, A. H., 271Consden, R., 89Constable, B. J., 94Cook, C. D., 174Cooke, R. A., 182Cope, C. L., 184Copeman, W. S. C., 378*Costa Bertani, G., 100Coste, F., 92, 172Court, D., 263*Coutu, L.-L., 276Coventry, M. B., 264Coyer, A. B., 378Crabbe, J., 98

*Crain, D. C., 178

Cudkowicz, L., 381Curtarelli, G., 97Cuthbertson, D. P., 96Cyriax, J., 181

*Dale, M., 84Dalgaard, 0. Z., 80Daneo, V., *100, *180, *267,

*276, *379, *385*Daniels, R. S., 171Dauby, J., 270Dave, B. T., 388Davies, H. R., 379Davis, A. E., 265Davis, J. S., 382*Dearing, W. H., 276Debeyre, J., 177Debeyre, N., 91Decker, J. P., 78*Decourt J., 99*D6court, L., 379Delbarre, F., 92Demartini, F., 377Denis, A., 92Dent, R. V., 176

*Dickgiesser, F., 180*Dilling, N. V., 87*Dimson, S. B., 172Djian, A., 177, *178Dodds, C., 378Dods, L., 387

*Dollfus, M. A., 99*Dorffel E., 178*Dorgan, J. A., 178*Douthat, A., 382*Dubois-Poulsen, A., 99Ducommum, P., 268Ducommum, S., 268*Durupt, L., 100*Dussy, J., 275

Easson, E. C., 379*Eastham, R. D., 385Edholm, 0. G., 175Ehring, F. J., 381

*Ehrlich, M., 264Einaudi, G., *262, *267, *385Eisler, M., 96*Elghammer, H. W., 78Ellis, L. B., 169Ellman, P., 381

*El Ramly, Z., 171*El-Sherif, A., 171Elster, S. K., 386*Engleman, D. P., 178*Ensign, D. C., 89Epstein, N., 76Essellier, A. F., 266*Eyquem, A., 91

*Farneti, P., 261Fearnley, M. E., 263, 378Ferciot, C. F., 262Ferencz, C., 76Ferey, D., 182

*Fernandes, J. M., 379*Fernandez del Vallado, P., 38*Femandez y Fernandez, M.,

*275*Fernando, P. B., 379*Ferond, M., 390Ferriman, D. G., 273

*Fiebig, W., 382*Filogamo, G., 276Fine, M., 99Finney, R., 176

402

Finzi, N. S., 174Fischer, F., 181Fleminger, J. J., 275

*Florentin, P., 379*Follis, R. H., 180*Forest, G. K. de, 266Forestier, J., 265

*275, Forsyth, C. C., 82Fortin, P., 390Fourman, P., 269

*Fournier, A., 262Frain, J. B., 271Franceschini, P., 99

*Francesconi, M., 78*Francon, J., 99Francon, F., *100, *382Freedman, A. L., 180Freedman, H. H., 96Freeland, D., 86Friedman, H. H., 85Friis-Hansen, B., 181

*Frolich, D., 91*Fry, R. J., 84Fuchs, U., 172

Galan, E., 182*Galmiche P., 275Garai, O., 273Garcia, O., 182Garcia Faez, O., 182

*Gassot, B., 264Gaudin, G., 383

*Gaufroy, B., 260*Gautier, A., 87Gelfand, M. L., 272Gelli, G., 168Georg, J., 181

*Gervay, F., 172*Giardulli, A., 88Gigglberger, H., 174Ginsburg, I. W., 79

*Gitelson, S., 276Gleason, I. O., 384Glick, S., 258Glover, R. P., 169*Glyn, J., 385Glyn, J. H., 378Glynn, L. E., 89Goelkel, A., 172Goldman, A., 380Goldner, F., 86

*Goldstein, A. S., 83*Goobar, J. P., 382Goodman, H. C., 80*Goodson, W. H., 261Gordon, D. M., 273*Graber-Duvemay, J., 172Graham, W., *178, *265

*Grasse, L. A., 178*Gray, J. W., 87Greene, R., 273Greenhouse, J., 271

*Grichener, A., 100Grifone, J. W., 376

*Gsell, O., 83*Guck, J. K., 88

5 Guirao Perez, M., 385*99, *Gulotta, G. A., 171

Gutman, A. B., 383

*Haas, W. R., 88Havermark, N. G., 97Hain, K., 76Hamburg, D. A., 274Hamerman, D. J., 386Haninger, J., 77

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Harken, D. E., 169*Harmston, G. J., 88*Harris, L. H., 379Harris, L. J., 94Harrison, M. H. M., 84Hart, F. D., *178, 386

*Harter, F., 180Hartfall, S. J., 183*Hartmann, F., 264Harvey, G., 174, 262Haserick, J. R., 271Hastrup, B., 181Hawn, C. Van Z., 78Heather, A. J., 79Helper, H. N., 76*Hembrow, C. H., 173Henderson, L. L., 77

*Henriksen, E., 99Henry, W. L., 183*Hernandez, F. A., 276Hersh, A. H., 82Herxheimer, H., 273Higgins, C. C., 95Hirschfeld, I., 258

*Holder, R., 78Hollander, J. L., 180, *264, 271*Hollevoet, -, 88Hollinger, N. F., 90Holst, J. E., 80Homan, J. D. H., 273Houghton, L. E., 389*House, F. B., 84Houser, H. B., *171, 376

*Hogutbk, J., 87Horava, A., 268Horler, A. R., 269Howarth, S., 175 bisHudson, B., 80Hudson, P. B., 179Hughes, R. E., 94Hurlock, B., 184

*Ibrahim, M., 171 bis*Irby, R., 264Ishibashi, H., 382Isemein, L., *172, *262

Jackson, R. L., 169Jacqueline, F., *91, 382Jamison, W. L., 376Janeway, C. A., 89

*Janson, P., 177Janton, 0. H., 169Jawetz, E., 267Jeanjean, Y., 93Jeffrey, M. R., 82, 172

*Jennings, G. H., 383Jessar, R. A., 85, *264Joag, G. G., 388*Jochem, E., 91Johnson, A. L., 76Johnson, H. M., 262Jones, M. H., 83Jones, R., 91*Josenhans, G., 276*Justin-Besancon, L., 262

Kaiser, G. D., 266Kalbak, K., 181

*Kalliomaki, L., 171*Kaminester, C. E., 88Kassirskaya, E. G., 265Keating, F. R., 96, 184Kecmanovid, Z., 272*Keenan, G. F., 178Kellie, A. R., 79Kelly, H. G., 169Kennedy, M. C. S., 273Kennedy, R. L. J., 382Kern, A. B., 270Kersley, G. D., 377

*Kieliotis, W., 171Kilpatrick, G. S., 260Kishimoto, S., 99Kitchell, J. R., 376Kleinberg, W., 96*Kono, M., 382*Kresbach, E., 87*Kreutzer, R., 171*Kuipers, R. K. W., 275Kulka, J. P., 171

*Kurtz, C. M., 78

Kuschner, M., 169Kuzell, W. C., 383

INDEXMenichini, G., 168

*Merrick, E. Z., 87Merrill, E. R., 267

Labourdette, J. M., 182 Methot,-, 168Lamont-Havers, R. W., 85 Meyer, K. A., 81*Lang, F. J., 178 Miall, W. E., 260Langendorf, R., 168 *Miccoli, G., 261Larson, E., 180 *Michel, R., 88Laurent, F., 172 Michotte, L. J., 270Lawrence, J. S., 100, 173 Miller, H., 263Lee, P. R., 380 Milne, M. D., 176Van Leeuwen, L., 273 Miloievic, B., 272

*Lefkovitz, A. M., 83 Mittelman, A., 179Lehtinen, L., 79 Mizukawa, T., 99

*Lehtinen, M., 379 Modell, S., 274*Lentini, D., 261 Moeschlin, S., 93, 98Leonard, J. C., 87, 386 *Moffatt, J. L., 382Lepri, G., 390 Molchanova, L. A., 100

*Leshin, N., 88 Montgomery, M. M., *178, 266Leslie, A., 94 *Montserrat, S., 382 bisLevernieux, J., 263 Moore, L. V., 77Levieff, L., 169 *Van Moorleghem, J., 172Levin, M. H., 178 Morandi, L., 266Levis, S., 270 *Moreau, G., 262Levy-Lebhar, J. P., 177, *178 *Moreno, A. R., 276Lewis, A., 275 Morgan, T. E., 389 bis

*Lewis, G. W., 382 Morley, M., 263Lewis, R. A., 388 Movitt, E. R., 265

*Lewitus, Z., 382 Mulholland, H. F., 263*Liess, G., 178 Muller. G. M., 83Lidvre, J.-A., *178, *264 *Muratore, F., 178Lintz, R. M., 378*Lima, M. C., 379 Nadell, J., 377*Lockie, L. M., 178 *Nakayama, T., 382*Lovgren, O., 83 *Nassim, J. R., 87*Lofty Abdel Rahman, M., 171 bis *Natale, P., 87Long, D. A., *260, 267 Natenshon, A. L., 381*Louyot, P., 379 Natterer, G., 84Lovell, R. R. H., 80 Naugler, W. E., 383Lowell, F. C., 99 Neligan, G. A., 175Lowman, E. W., 380 Nerenberg, S. T., 267Lubschez, R., 76 Neustadt, D. H., *264, 385Lubow, H., 170 Neutelings, J. P. H., 273Lucherini, T., *87, *97, *100, 180 *Neuwirth, E., 178Luderitz, B., 81 *Newman M. K., 83Lukid, D., 272 Newns, G. R., 171*Lutembacher, R., 180 Nichols, H. T., 376*Lyons, A. R., 379 Nordenson, N. G., 97

Norymberski, J. K., 90*Macinot, -, 379 Nuffield Foundation Joint Com-*Mackiewicz, S., 180 mittee on Cortisone and ACTHMcCall, M. F., 182 in Chronic Rheumatic Diseases,McCluskey, R. T., 91 261McCue, C. M., 260 *Nyfos, L., 99McIntosh, H. W., 84, 99*MacKnight, J. C., 264 *O'Brien, D. J., 381

McNeely, W. F., 169 O'Connell, J. H., 263

McSwiney, R. R., 268 Oka, M. J., 81, 86, *171McVay, L. V., 170 Oldham, P. D., 260Mainoli, S., 380 Oleesky, S.. 95

*Maisondieu, M., 275 Oliner, L., *88, 183*Malaguzzi Valeri, C., 87 O'Neill, T. J. E., 169

Malitz, S., 274 *Ono, M., 382Malkina, M. G., 78 *Orstrom, A., 83

*Mancini, B., 381 *Ortona, L., 377Mankle, E. A., 383 Ory, M., *173, *276Mann, P., 179 Osborne, J. A., 80

*Manzanares, E., 100 Ott, V. R.,8JMaranon, G., *99, *275 Den Oudsten, S. A., 273*Marczynska-Robowska, M., 379 Overbeek, G. A., 273Marini, C., 388Marson, F. G. W., 88 Panigatti, F., 258Marti, H. R., 266 *Pannewitz, G. von, 173Marticke, G., 262 Pap, L. de 92Martin, G. J., 96 Pasquariello, G., 385Martin, J. R., 98 Patel, D. J., 258Mason, R. M., 264 Patel, J. C., 388Mathews, S. S., 83 Patley, H., 263Matteis, F. de, 258 Pattee, C. J., 98Di Matteo, J., 390 Pavlov, N. M., 100Matthews, B. F., 173 *Paylan, A., 88*Maurice, P., 385 Peabody, J. W., 274Maycock, R. L., 91 Pemberton, M., 261*Mayerhofer, F., 87 Perez-Stable, M., 182Meanock, I., 263 *Peterman, E. A., 87 bisMedical Research Council, Panel on *Petersen. K. Birkum, 84

the Haematological Applications *Peterson, W. L., 171of ACTH and Cortisone, 272 *Picchio, A., 174

Sub- Piccinelli, O., 380committee, 261 *Pierson, B., 379

Medoff, A. S., 384 *Pilkington, T., 87*Melloni, F., 381 *Pirtkien, R., 379

403*Platoff, G. E., 87*Plugge-Heidelberg, H., 83Pohl, W., 378

*Porro, F., 381*Poulin, J. E., 99Poutasse, E. F., 95Prader, A., 269*Preston, R. L., 262*Prevot, A.-R., 261Prosiegel, R., 172Prunty, F. T. G., 268*Puig Leal, J., 385

Quigley, T. B., 265

Ragan, C., 85, *178, 377*Raimondo, F. di, 87Ramey, E. R., 183*Ramirez Gilbon, J., 99*Ramunni, M., 178Randall, C. C., 175Ravault, P., 88*Rechenberg, H. K. von, 83*Redon, M., 172Riising, P. V., 80Rivo, J. B., 178

*Rizzente, S., 382Robbins, S. L., 78Robecchi, A., 173, 270, *275Roberts, E., 76Robin, J., 91, 92*Robinson, D., 87Robinson, R. C. V., 181

*Robinson, W. D., 178Rohn, R. J., 86Rohrschneider, W., 381*Rome, H. P., 276Ronchese, F., 270Root, S. W., 179

*Ropes, M. W., 178*Rose, D. L., 261*Rosenberg, E. F., 178Rossi, G., *261, *262, *379

*Rossing, P., 382Roussak, N. J., 176Routh, J. I., 169*Rouveix, J., 260Roy, J., 182Rubens-Duval, H., 262Rubinstein, M. A., 180Rusoff, J. H., 258

Salassa, R. M., 96, 184Sins Sola, L., *89 bis, *382Saphir, O., 168

*Sardini, G., 377*Sargent, A. F., 178*Saslaw, M. S., 276Satoskar, R. S., 388

*Sauer, W. G., 276Savage, O., 378Scalabrino, R., 97, 385Schaal, K., 84Schaffarzick, R. W., 383Schiller, I. W., 99

*Schirmer, K., 390*Schliephake, E., 100*Schlossmann, K., 83Schmid, J., *83, *91, *390

*Schneider, H., 178*Schnitzer, A., 177Schwartz, M., 181Schwartz, S., 85Schwartzman, J., 170

*Scuro, L. A., 377*Secondo, G., 100Seddon, H. J., 83Selye, H., 268

*Serane, J., 264*Serra, A. Peralba, 89*Severens, J. M., 180Sevitt, S., 275Seze, S. de, 91, 92, 177, *178, 263

*Shapira, T. M., 88Sharp, G., 96Sharp, J., 379Sheehan, H. L., 386Sherman, W. B., 182Shubik, P., 270

*Sichere, R. M., 264*Siebenmann, R., 99*Sigler, J. W., 89

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404Sikula, L., 77Silver, M., 385Singer, B., 182Sladden, R. J., 100*Slocumb, C. H., 275Smelin, A., 180Smith, D. T., 389 bisSmith, E. K., 169*Smyth, C. J., 178*Snow, W. G., 87*Sobhy, M., 99Soffer, L. J., 386Sokoloff, L., 91, 384Soloff, L. A., 169Solomon, W. M., 82Solomons, B., 388Someya, K., 382

*Sorour, A., 171Souli6, P., 390Sperling, S. C., 83Sprague, R. G., 96, 184Sprechler, M., 181Sprunt, D. H., 170

*Srbova, D., 87Stanier, W. M., 89Stark, H., 390

*Stawecki, J., 83Stecher, R. M., 82Steck, I. E., 266

*Steel, S. J., 382*Steele, C. W., 83Steele, J. M., 380Steinbeck, A. W., 269Steiger, W. A., 79Steinberg, C. LeR., 81Steinbrocker, O., 85, *264, 385Steiner, G., 176

*Stepantzchitz, G., 87

ANNALS OF THE RHEUMATIC DISEASESSterne, J., 383Stewart, J. S., 276Stollerman, G. H., 258Stolzer, B. L., 376Storey, G., 86, *381Stubbs, R. D., 90

*Suarez, Gonzalez, 172Sugihara, H., 382Sullivan, R. D., 91Summa, C., 97, *180 bisSummers, V. K., 386Suzue, T., 99

*Svartz, N., 83Svien, H. J., 382Swift, S., 387

Takagi, Y., 99*Talbot, B., 78*Talbott, J. H., 89*Tarnopolsky, S., 382*Taubenhaus, M., 88*Taylor, A. R., 382Teixeira, M. A., 92*Telkka, A., 379Thing, E., 98 bisThompson, M., 86Tonning, H. O., 171*Toone, E. C., 264Traynor, J. A., 84

*Treichler, J., 382Tricot, R., 390Troisier, O., 181Trubek, M., 85Trueta, J., 84

*Trutschel, W., 91Turiaf, J., 93Turner, P. P., 273

Udell, L., 271*Uehlinger, E., 99Uhrbrand, H., 266Unanue, E., 182

Vaughan-Morgan, J., 273Veraguth, P., 382

*Verges, G., 276Viergiver, E., 259Van der Vies. J., 273*Vignon, G., 88*Vilaseca, J. M., 264Villiaumey, J., 262Vines, R., 387Virkkunen. M., 79Vollmer, H., 182Volpicelli, M., 97, * 180 bis

Wade, A. P., 79*Wager, O., 180*Wahl, M., 390*Wall, P., 83Wallis, A. D., 259 bisWang, P., 169Wanzer, S. H., 389 bisWarmong-Larsen, A., 181Warren, R. F., 179Warrick, C. K., 175*Warum, F., 390*Wasz-Hockert, O., 91*Watkins, A. L., 83Webb, J. H., 382Wedgwood, R. J. P., 174, *174Weidmann, H., 267

*Weil, M.-P., 264Weiss, R. S., 271

Weiner, M., 380Weinstein, L., 90Weissenbach, R., 92Welch, R. G., 82*Wells, B. B., 91*Werblow, S. C., 276West, H. F., 90, 171*Wetheimer, P., 88*Wheatley, D., 177Wiener, S., 76Wiesel, L. L., 261, 272

*Wijenaike, W., 379*Wildholm, O., 91Wilkins, L., 387*Wilkoszewski, E., 171Wilson, M. G., 76Wilson, W. M. G., 99*Wolf, J., 88*Wollaeger, E. E., 276Wolpaw, R., 82Womack, C. R., 175Wulff, H., 181

*Yoshida, T., 382Yourish, N., 88

*Zacco, M., 390Zaontz, J. B., 170Zarafoneits, C. J. D., 79Zatichni, J., 169

*Zinn, W., 178Zivin, S., 266Zizine L., 93Zoeckler, S. J., 180Zurukzoglu, W., 98