libra double beam

Upload: pkuchonthara383

Post on 14-Apr-2018

217 views

Category:

Documents


0 download

TRANSCRIPT

  • 7/30/2019 Libra Double Beam

    1/8

    High performance instruments with added application valuefor academia, research and industry

    Biochrom LibraUV-Visible Spectrophotometers

    New

    DoubleBeam

    Spectrophotomete

  • 7/30/2019 Libra Double Beam

    2/8

    Biochrom Libra Real Choice in Spectrophotometry

    Biochrom are experts in spectrophotometry and

    have manufactured quality scientific instruments

    for forty years.

    Our spectrophotometry ranges include not only

    Biochrom Libra spectrophotometers but also

    Biochrom WPA spectrophotometers and

    colorimeters for education and life sciences.

    As LKB Biochrom we launched the now famous

    Ultrospec range in 1982 followed by the

    GeneQuant range of spectrophotometers.

    Our name may not be familiar but our instruments

    are found in hospitals, universities and industrial

    laboratories worldwide. We supply our

    instruments through a global network of

    independent distributors and also manufacture for

    some of the worlds finest scientific companies.

    All Biochrom instruments are CE marked and are

    manufactured under a rigorous quality system.

    Biochrom Libra - why compromise?

    The Biochrom Libra range is about freedom to work

    the way you want to. Dont settle for anything less

    than your perfect solution. From academia to

    industry, Biochrom has the spectrophotometer to suit

    your particular application needs - without requiring

    you to compromise on performance or overspend.

    The Biochrom Libra range of UV/Visible

    spectrophotometers extends from the practical, split

    beam laboratory workhorse, to high performance,

    variable bandwidth, double beam systems ideal forthe highly regulated pharmaceutical environment.

    With common hardware and software platforms, all

    Biochrom Libra instruments provide flexible, robust,

    reliable measurements and are easy to use

    and afford.

    Our new instruments are designed to be flexible with

    a choice of software and a range of interchangeable

    accessories that are easy to install. Select the

    configuration that fits your needs and dont pay for

    unnecessary features that you wont use.

  • 7/30/2019 Libra Double Beam

    3/8

    Many sample measurements taken on aspectrophotometer are straightforwardand benefit from the speed and ease-of-use offered by a stand-alone instrument.The wide ranging applications foundwithin todays laboratories call for

    flexibility. Now Biochrom Libra instrumentsdeliver high function applicationcapabilities in a stand-alone instrument.By incorporating the latest technology andcustom written, application-led software,Biochrom Libra spectrophotometers havethe advanced features to meet yourlaboratorys needs, bringing you thebenefits of both flexibility and walk-upefficiency without compromise.

    All stand-alone instruments offer:

    I Colour touchscreen display

    Full control of all instrumentparameters

    Overlay of multiple wavelengthscans and kinetic curves

    Post run manipulation of data

    I USB interfaces for data storageand export

    Interface for USB memory sticknext to the display allows storageof methods and data in secureand ASCII formats

    Interface for USB cableconnection to PC

    I Full suite of software applicationsprovided as standard

    Single wavelength measurement

    in Absorbance, % Transmissionand concentration measurementsusing factors

    Wavelength scanning

    Calibration curves

    Kinetics

    Pre-stored Life Scienceapplications

    Trace Manager for manipulationof data stored on the instrumentor USB memory stick

    I Software security features

    Method storage including allinstrument and accessoryparameters with passwordprotection

    Multi-level user login

    I Multiple language options

    I Equation Editor

    Turn your instrument into a customapplication analyzer by setting up storedmethods including calculations based on

    measured sample data, for example:Absorbance difference and ratios.Application examples include: olive oiland chlorophyll analysis and toluene inhexane resolution check.

    I Choice of data export methods

    All stand-alone Biochrom Librainstruments offer users a choice in exportand print functionality with selectionparameters stored as part of any method

    Export to PC via USB cable(standard)

    Built in printer (optional)

    Export to a PC via Bluetooth

    (optional)

    Stand-Alone Instruments

  • 7/30/2019 Libra Double Beam

    4/8

    PC Control

    Modules Resolution Resolution Resolution ResolutionLite Life Science CFR

    Quick Readand Quick Scan

    WavelengthScanning,

    Kinetics, QuantitativeCalibrationCurves

    Validation

    Method Developer

    Life Science Methods

    21 CFRPart 11

    Compliance

    Accessory

    Control

    For many users having an external PC tocontrol their spectrophotometer andmanipulate data gives them the ultimate inflexibility and control. Whether looking forsmall differences in multiple spectraloverlays, carrying out post-run manipulationson large numbers of samples or simplyfulfilling regulatory requirements, BiochromsResolution software has the flexibility towork in the way you want.

    Resolution software is supplied in differentmodules to meet the applicationrequirements of different customer groupsand offers a simple upgrade path shouldyour requirements change.

    Choose:

    I Resolution Lite for Quick Read and fastscanning only

    I Resolution for all routine measurements

    I Resolution Life Science for nucleicacids, proteins and cell densitymeasurements

    I Resolution CFR if you need full 21 CFRpart 11 compliance

    Offering the familiar look and feel ofMicrosoft Office 2007, Resolution softwareis compatible with Windows XP, WindowsVista and Windows 7 operating systems.Data export options include Microsoft Wordand Excel plus Adobe PDF formats.

    European Pharmacopoeia(EP) Compliance

    Customers manufacturingpharmaceutical products incompliance with the EP look for aUV/Visible spectrophotometer thatmeets the specifications defined inEP 2.2.25. This publishesspecifications for the control ofwavelength, Absorbance, stray light,resolution and spectral slit width.

    The specification for resolution statesWhen prescribed in a monograph,measure the resolution of theapparatus as follows: record thespectrum of a 0.02 % V/V solution oftoluene R in hexane R. The minimumratio of the absorbance at themaximum at 269 nm to that at theminimum at 266 nm is stated in themonograph. EP version 6.8 includesseven product monographs thatprescribe this ratio.

    To claim full compliance aninstrument should give a ratiogreater than 2.0.

    The Libra S70 with its fixed 1nm

    bandwidth and the S80 with itsvariable bandwidth both achievethis specification.

  • 7/30/2019 Libra Double Beam

    5/8

    With a large sample compartment theinstrument can be configured with quickchange accessories including sipper,temperature control accessories, longpathlength, test tube, and film holders.For the complete range of accessoriesplease see our website.

    Accessories

    www.biochrom.co.uk/select-a-spectrophotometer/

    This website tool helps you to find the ideal Biochrom spectrophotometer

    Biochrom Libra Software Functionality Comparison

    Software Stand-Alone Resolution Resolution Resolution ResolutionModules Instrument Lite Life CFR

    Software Science

    SingleWavelength

    Measurement

    WavelengthScanning

    ConcentrationStandard Curve

    Kinetics

    Validation

    Life ScienceMethods

    Custom MethodDevelopment

    21 CFR Part 11Compliance

    Quantitation usingcalibration curves

    with multiplestandards and a

    choice of curve fits

    Sample overlays, automatic feature

    detection and post run data

    manipulation

    Sample overlays, automatic feature detection and

    post run data manipulation, spectral scans and

    spectral arithmetic manipulations

    Single or multiple wavelength measurementsin Absorbance, % Transmission or concentration

    including full instrument control, batch processingof sample data and calculations

    on collected data

    Generation of calibration curves includingfull instrument and accessory control, choice ofline fit, QC limit testing and statistical analysis

    of sample data

    Serial (or parallelmeasurements with

    the optional cellchanger) including

    sample overlaysand post run data

    manipulation

    Absorbance versus time measurements on

    single or multiple cells (with optional cell changer),multiple sample overlays, batch processing ofsample data and post run sample calculations

    and manipulations

    DNA, RNA & Oligoconcentration and

    purity measurementwith optional

    wavelengthscanning.

    CyDyeTM DNAquantitation.

    Tm calculation.Protein

    concentration bydirect UV

    measurement orBradford, Biuret,Lowry or BCAcolorimetric

    methods

    Equation Editorallows the setup of stored

    methods that canincludecalculations based

    on measuredsample data e.g.Absorbance ratioand difference.

    Ability to set updifferent users

    as part ofdefined groups.

    Audit trail.Electronicsignature

    Software module that allows users to enterand store full details of their Certified Reference Materials

    (CRMs) and schedule tests to be carriedout at defined intervals to meet their Standard

    Operating Procedures. Users are prompted to insert the specifiedCRM at the scheduled time and the system automatically checks the

    performance against the instrument specification.

    DNA, RNA & Oligo concentration& purity measurement

    Protein quantitation via direct UVmethods or BCA, Buiret, Bradford,Lowry & Colloidal Gold methods

    Cell Density measurement

    The Method Developer module allows

    custom methods to be set up in all applications.These can include sample prompts containing

    information such as method SOP timings and theability to lock individual method parameters

    Fixed wavelength, Abs/%T,Concentration (factor)

  • 7/30/2019 Libra Double Beam

    6/8

    Application Sectors

    QUALITY CONTROL

    Our profitability relies on preciseanalytical data. To keep productionrunning at optimal efficiency we needhigh throughput measurements andresults must be entirely dependableacross the long termManufacturingquality control (QC) manager.

    TAKE A LOOK AT THE BIOCHROMLIBRA S70

    I Fully European Pharmacopoeiacompliant system

    I Password login to protect methods

    I High performance system withnarrow bandwidth for precise analysis(toluene hexane ratio of >2.0)

    I Optional validation logbook forIQ/OQ/PQ

    The Biochrom Libra S70 is an affordable,high specification instrument with a 1 nmbandwidth intended for busy, multi-useranalysis in pharmaceutical, QC, analyticaland research laboratories. Forlaboratories requiring high performanceand 21 CFR compliance consider adding

    Resolution CFR module.

    MULTI-USER LABORATORIES

    We need a flexible system that scientistscan walk up to and use for theirindividual projects. It needs to be easy touse, hardworking and robust, but havethe flexibility to cover the whole rangeof applicationsAcademic PhDsupervisor.

    TAKE A LOOK AT THE BIOCHROMLIBRA S50 OR S60

    I Long life Xenon lamp technology forlow cost of ownership

    I All application software is built in - noextra modules to buy

    I Multi-user analytical instrument withsecure login

    I Custom calculation facility usingEquation Editor

    I Large sample compartment makingchanging accessories easy

    I Built in Life Science methodsincluding nucleic acid concentrationand purity

    The Biochrom Libra S50 and S60 models

    are robustly designed to deliver reliable,low maintenance UV/Visiblespectrophotometry in environments withmultiple users. Users can quickly andeasily walk up to the instrument, set up asample, select the appropriatemeasurement protocols and collect theresults. The convenient USB port enablesindividual users to load personal methodsand transport data. Good LaboratoryPractice (GLP) performance qualificationacross multiple user accounts is facilitatedvia a different security level access.

    The Biochrom Libra S60 offers theadditional flexibility and familiarity of adouble beam optical design. For moreadvanced data manipulation featuresconsider adding Resolution software.

    RESEARCH/METHOD DEVELOPMENT

    We develop methods for our factoriesworldwide so we need a highperformance system and worldwideregulatory compliance with full traceabilityis an absolute must. However we cantpredict the future, so we need theflexibility to handle all UV-Vis applicationsPharmaceutical method developmentscientist.

    TAKE A LOOK AT THE BIOCHROMLIBRA S80PC UPGRADED WITHRESOLUTION CFR

    I High performance variable bandwidth

    UV-Visible spectrophotometerI Full European Pharmacopoeia

    compliance

    I 21 CFR part 11 compliance usingResolution CFR

    I Custom calculation facility formethod development in theResolution Software

    I Wide range of accessories that areeasily changed

    Biochroms new top of the rangehigh performance instrument.The Biochrom Libra S80 gives consistentresults of the highest quality. Satisfying allrequirements for EuropeanPharmacopoeia (EP) and optional systemqualification. The Biochrom Libra S80delivers Biochroms ultimate resolutionand precision.

  • 7/30/2019 Libra Double Beam

    7/8

    For a full list of accessories and technical specifications for all instruments

    see www.biochrom.co.uk

    Biochrom Libra Options and Order Codes

    S50 S50PC S60 S60PC S70 S70PC S80 S80PC

    S50 S50PC S60 S60PC S70 S70PC S80 S80PC

    BeamConfiguration

    Lamp

    Wavelength Range

    Bandwidth

    Detector

    PhotometricRange

    Colour TouchScreen

    Built in Software

    Resolution PC

    Control Software

    USB Storage

    Accessories

    Built in ThermalPrinter

    Method Storage

    CE Mark

    EP Compliance

    IQ/OQ/PQ

    Languages

    Cell Compatibility

    Power

    Requirement

    Weight

    Dimensions

    (WxDxH)

    Instrument only

    With ThermalPrinter

    With Bluetooth

    With ThermalPrinter andBluetooth

    Split beam

    (with reference beamcompensation)

    190-1100nm

    2nm 1nm Variable (0.5,1,2,4nm)

    Double Beam

    Xenon Deuterium/Tungsten

    Dual Solid State Silicon photodiode

    -4.000A to 4.000A

    Optional Standard Optional Standard Standard Standard Standard Standard

    Optional Optional Optional Optional

    Up to 90 Up to 90 Up to 90 Up to 90on-board, Unlimited on-board, Unlimited on-board, Unlimited on-board, Unlimitedunlimited on PC unlimited on PC unlimited on PC unlimited on PCvia USB via USB via USB via USB

    Optional Optional Optional Optional Optional Optional Optional Optional

    English

    English

    English

    English

    English

    English

    English

    EnglishFrench French French French

    German German German GermanSpanish Spanish Spanish Spanish

    Cuvette, Microcell*, 1-100mm Pathlength Cell*, Test Tube*, Film*

    100-240V AC, 50/60Hz, 150VA

    17kg (37.5lb)

    54 x 46 x 32cm (21.3 x 18.1 x 12.6 inches)

    80-7000-01 80-7000-00 80-7000-11 80-7000-10 80-7000-21 80-7000-20 80-7000-31 80-7000-30

    80-7000-02 80-7000-12 80-7000-22 80-7000-32

    80-7000-03 80-7000-13 80-7000-23 80-7000-33

    80-7000-04 80-7000-14 80-7000-24 80-7000-34

    Order Codes

    * optional accessories

    Microsoft, Windows and Excel are registered trademarks ofMicrosoft Corporation

    CyDye is a trademark of GE Healthcare Companies

    Adobe is a registered trademark of Adobe SystemsIncorporated

    Ultrospec and GeneQuant are registered trademarks ofBiochrom Ltd.

    Bluetooth is a registered trademark of the Bluetooth SIG

  • 7/30/2019 Libra Double Beam

    8/8

    Biochrom Ltd22 Cambridge Science Park,Milton Road, Cambridge CB4 0FJ UK

    Tel: +44 (0)1223 423723Fax: +44 (0)1223 420164Email: [email protected]

    www.biochrom.co.uk

    Biochrom US84 October Hill Road,Holliston, MA 01746-1388 USATel: 877- BIO-CHROM (877-246-2476)

    (Toll free)Fax: 508-429-5732

    email: [email protected]

    Distributors worldwide:

    80-

    7000-35

    issue

    1