libra double beam
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High performance instruments with added application valuefor academia, research and industry
Biochrom LibraUV-Visible Spectrophotometers
New
DoubleBeam
Spectrophotomete
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Biochrom Libra Real Choice in Spectrophotometry
Biochrom are experts in spectrophotometry and
have manufactured quality scientific instruments
for forty years.
Our spectrophotometry ranges include not only
Biochrom Libra spectrophotometers but also
Biochrom WPA spectrophotometers and
colorimeters for education and life sciences.
As LKB Biochrom we launched the now famous
Ultrospec range in 1982 followed by the
GeneQuant range of spectrophotometers.
Our name may not be familiar but our instruments
are found in hospitals, universities and industrial
laboratories worldwide. We supply our
instruments through a global network of
independent distributors and also manufacture for
some of the worlds finest scientific companies.
All Biochrom instruments are CE marked and are
manufactured under a rigorous quality system.
Biochrom Libra - why compromise?
The Biochrom Libra range is about freedom to work
the way you want to. Dont settle for anything less
than your perfect solution. From academia to
industry, Biochrom has the spectrophotometer to suit
your particular application needs - without requiring
you to compromise on performance or overspend.
The Biochrom Libra range of UV/Visible
spectrophotometers extends from the practical, split
beam laboratory workhorse, to high performance,
variable bandwidth, double beam systems ideal forthe highly regulated pharmaceutical environment.
With common hardware and software platforms, all
Biochrom Libra instruments provide flexible, robust,
reliable measurements and are easy to use
and afford.
Our new instruments are designed to be flexible with
a choice of software and a range of interchangeable
accessories that are easy to install. Select the
configuration that fits your needs and dont pay for
unnecessary features that you wont use.
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Many sample measurements taken on aspectrophotometer are straightforwardand benefit from the speed and ease-of-use offered by a stand-alone instrument.The wide ranging applications foundwithin todays laboratories call for
flexibility. Now Biochrom Libra instrumentsdeliver high function applicationcapabilities in a stand-alone instrument.By incorporating the latest technology andcustom written, application-led software,Biochrom Libra spectrophotometers havethe advanced features to meet yourlaboratorys needs, bringing you thebenefits of both flexibility and walk-upefficiency without compromise.
All stand-alone instruments offer:
I Colour touchscreen display
Full control of all instrumentparameters
Overlay of multiple wavelengthscans and kinetic curves
Post run manipulation of data
I USB interfaces for data storageand export
Interface for USB memory sticknext to the display allows storageof methods and data in secureand ASCII formats
Interface for USB cableconnection to PC
I Full suite of software applicationsprovided as standard
Single wavelength measurement
in Absorbance, % Transmissionand concentration measurementsusing factors
Wavelength scanning
Calibration curves
Kinetics
Pre-stored Life Scienceapplications
Trace Manager for manipulationof data stored on the instrumentor USB memory stick
I Software security features
Method storage including allinstrument and accessoryparameters with passwordprotection
Multi-level user login
I Multiple language options
I Equation Editor
Turn your instrument into a customapplication analyzer by setting up storedmethods including calculations based on
measured sample data, for example:Absorbance difference and ratios.Application examples include: olive oiland chlorophyll analysis and toluene inhexane resolution check.
I Choice of data export methods
All stand-alone Biochrom Librainstruments offer users a choice in exportand print functionality with selectionparameters stored as part of any method
Export to PC via USB cable(standard)
Built in printer (optional)
Export to a PC via Bluetooth
(optional)
Stand-Alone Instruments
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PC Control
Modules Resolution Resolution Resolution ResolutionLite Life Science CFR
Quick Readand Quick Scan
WavelengthScanning,
Kinetics, QuantitativeCalibrationCurves
Validation
Method Developer
Life Science Methods
21 CFRPart 11
Compliance
Accessory
Control
For many users having an external PC tocontrol their spectrophotometer andmanipulate data gives them the ultimate inflexibility and control. Whether looking forsmall differences in multiple spectraloverlays, carrying out post-run manipulationson large numbers of samples or simplyfulfilling regulatory requirements, BiochromsResolution software has the flexibility towork in the way you want.
Resolution software is supplied in differentmodules to meet the applicationrequirements of different customer groupsand offers a simple upgrade path shouldyour requirements change.
Choose:
I Resolution Lite for Quick Read and fastscanning only
I Resolution for all routine measurements
I Resolution Life Science for nucleicacids, proteins and cell densitymeasurements
I Resolution CFR if you need full 21 CFRpart 11 compliance
Offering the familiar look and feel ofMicrosoft Office 2007, Resolution softwareis compatible with Windows XP, WindowsVista and Windows 7 operating systems.Data export options include Microsoft Wordand Excel plus Adobe PDF formats.
European Pharmacopoeia(EP) Compliance
Customers manufacturingpharmaceutical products incompliance with the EP look for aUV/Visible spectrophotometer thatmeets the specifications defined inEP 2.2.25. This publishesspecifications for the control ofwavelength, Absorbance, stray light,resolution and spectral slit width.
The specification for resolution statesWhen prescribed in a monograph,measure the resolution of theapparatus as follows: record thespectrum of a 0.02 % V/V solution oftoluene R in hexane R. The minimumratio of the absorbance at themaximum at 269 nm to that at theminimum at 266 nm is stated in themonograph. EP version 6.8 includesseven product monographs thatprescribe this ratio.
To claim full compliance aninstrument should give a ratiogreater than 2.0.
The Libra S70 with its fixed 1nm
bandwidth and the S80 with itsvariable bandwidth both achievethis specification.
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With a large sample compartment theinstrument can be configured with quickchange accessories including sipper,temperature control accessories, longpathlength, test tube, and film holders.For the complete range of accessoriesplease see our website.
Accessories
www.biochrom.co.uk/select-a-spectrophotometer/
This website tool helps you to find the ideal Biochrom spectrophotometer
Biochrom Libra Software Functionality Comparison
Software Stand-Alone Resolution Resolution Resolution ResolutionModules Instrument Lite Life CFR
Software Science
SingleWavelength
Measurement
WavelengthScanning
ConcentrationStandard Curve
Kinetics
Validation
Life ScienceMethods
Custom MethodDevelopment
21 CFR Part 11Compliance
Quantitation usingcalibration curves
with multiplestandards and a
choice of curve fits
Sample overlays, automatic feature
detection and post run data
manipulation
Sample overlays, automatic feature detection and
post run data manipulation, spectral scans and
spectral arithmetic manipulations
Single or multiple wavelength measurementsin Absorbance, % Transmission or concentration
including full instrument control, batch processingof sample data and calculations
on collected data
Generation of calibration curves includingfull instrument and accessory control, choice ofline fit, QC limit testing and statistical analysis
of sample data
Serial (or parallelmeasurements with
the optional cellchanger) including
sample overlaysand post run data
manipulation
Absorbance versus time measurements on
single or multiple cells (with optional cell changer),multiple sample overlays, batch processing ofsample data and post run sample calculations
and manipulations
DNA, RNA & Oligoconcentration and
purity measurementwith optional
wavelengthscanning.
CyDyeTM DNAquantitation.
Tm calculation.Protein
concentration bydirect UV
measurement orBradford, Biuret,Lowry or BCAcolorimetric
methods
Equation Editorallows the setup of stored
methods that canincludecalculations based
on measuredsample data e.g.Absorbance ratioand difference.
Ability to set updifferent users
as part ofdefined groups.
Audit trail.Electronicsignature
Software module that allows users to enterand store full details of their Certified Reference Materials
(CRMs) and schedule tests to be carriedout at defined intervals to meet their Standard
Operating Procedures. Users are prompted to insert the specifiedCRM at the scheduled time and the system automatically checks the
performance against the instrument specification.
DNA, RNA & Oligo concentration& purity measurement
Protein quantitation via direct UVmethods or BCA, Buiret, Bradford,Lowry & Colloidal Gold methods
Cell Density measurement
The Method Developer module allows
custom methods to be set up in all applications.These can include sample prompts containing
information such as method SOP timings and theability to lock individual method parameters
Fixed wavelength, Abs/%T,Concentration (factor)
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Application Sectors
QUALITY CONTROL
Our profitability relies on preciseanalytical data. To keep productionrunning at optimal efficiency we needhigh throughput measurements andresults must be entirely dependableacross the long termManufacturingquality control (QC) manager.
TAKE A LOOK AT THE BIOCHROMLIBRA S70
I Fully European Pharmacopoeiacompliant system
I Password login to protect methods
I High performance system withnarrow bandwidth for precise analysis(toluene hexane ratio of >2.0)
I Optional validation logbook forIQ/OQ/PQ
The Biochrom Libra S70 is an affordable,high specification instrument with a 1 nmbandwidth intended for busy, multi-useranalysis in pharmaceutical, QC, analyticaland research laboratories. Forlaboratories requiring high performanceand 21 CFR compliance consider adding
Resolution CFR module.
MULTI-USER LABORATORIES
We need a flexible system that scientistscan walk up to and use for theirindividual projects. It needs to be easy touse, hardworking and robust, but havethe flexibility to cover the whole rangeof applicationsAcademic PhDsupervisor.
TAKE A LOOK AT THE BIOCHROMLIBRA S50 OR S60
I Long life Xenon lamp technology forlow cost of ownership
I All application software is built in - noextra modules to buy
I Multi-user analytical instrument withsecure login
I Custom calculation facility usingEquation Editor
I Large sample compartment makingchanging accessories easy
I Built in Life Science methodsincluding nucleic acid concentrationand purity
The Biochrom Libra S50 and S60 models
are robustly designed to deliver reliable,low maintenance UV/Visiblespectrophotometry in environments withmultiple users. Users can quickly andeasily walk up to the instrument, set up asample, select the appropriatemeasurement protocols and collect theresults. The convenient USB port enablesindividual users to load personal methodsand transport data. Good LaboratoryPractice (GLP) performance qualificationacross multiple user accounts is facilitatedvia a different security level access.
The Biochrom Libra S60 offers theadditional flexibility and familiarity of adouble beam optical design. For moreadvanced data manipulation featuresconsider adding Resolution software.
RESEARCH/METHOD DEVELOPMENT
We develop methods for our factoriesworldwide so we need a highperformance system and worldwideregulatory compliance with full traceabilityis an absolute must. However we cantpredict the future, so we need theflexibility to handle all UV-Vis applicationsPharmaceutical method developmentscientist.
TAKE A LOOK AT THE BIOCHROMLIBRA S80PC UPGRADED WITHRESOLUTION CFR
I High performance variable bandwidth
UV-Visible spectrophotometerI Full European Pharmacopoeia
compliance
I 21 CFR part 11 compliance usingResolution CFR
I Custom calculation facility formethod development in theResolution Software
I Wide range of accessories that areeasily changed
Biochroms new top of the rangehigh performance instrument.The Biochrom Libra S80 gives consistentresults of the highest quality. Satisfying allrequirements for EuropeanPharmacopoeia (EP) and optional systemqualification. The Biochrom Libra S80delivers Biochroms ultimate resolutionand precision.
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For a full list of accessories and technical specifications for all instruments
see www.biochrom.co.uk
Biochrom Libra Options and Order Codes
S50 S50PC S60 S60PC S70 S70PC S80 S80PC
S50 S50PC S60 S60PC S70 S70PC S80 S80PC
BeamConfiguration
Lamp
Wavelength Range
Bandwidth
Detector
PhotometricRange
Colour TouchScreen
Built in Software
Resolution PC
Control Software
USB Storage
Accessories
Built in ThermalPrinter
Method Storage
CE Mark
EP Compliance
IQ/OQ/PQ
Languages
Cell Compatibility
Power
Requirement
Weight
Dimensions
(WxDxH)
Instrument only
With ThermalPrinter
With Bluetooth
With ThermalPrinter andBluetooth
Split beam
(with reference beamcompensation)
190-1100nm
2nm 1nm Variable (0.5,1,2,4nm)
Double Beam
Xenon Deuterium/Tungsten
Dual Solid State Silicon photodiode
-4.000A to 4.000A
Optional Standard Optional Standard Standard Standard Standard Standard
Optional Optional Optional Optional
Up to 90 Up to 90 Up to 90 Up to 90on-board, Unlimited on-board, Unlimited on-board, Unlimited on-board, Unlimitedunlimited on PC unlimited on PC unlimited on PC unlimited on PCvia USB via USB via USB via USB
Optional Optional Optional Optional Optional Optional Optional Optional
English
English
English
English
English
English
English
EnglishFrench French French French
German German German GermanSpanish Spanish Spanish Spanish
Cuvette, Microcell*, 1-100mm Pathlength Cell*, Test Tube*, Film*
100-240V AC, 50/60Hz, 150VA
17kg (37.5lb)
54 x 46 x 32cm (21.3 x 18.1 x 12.6 inches)
80-7000-01 80-7000-00 80-7000-11 80-7000-10 80-7000-21 80-7000-20 80-7000-31 80-7000-30
80-7000-02 80-7000-12 80-7000-22 80-7000-32
80-7000-03 80-7000-13 80-7000-23 80-7000-33
80-7000-04 80-7000-14 80-7000-24 80-7000-34
Order Codes
* optional accessories
Microsoft, Windows and Excel are registered trademarks ofMicrosoft Corporation
CyDye is a trademark of GE Healthcare Companies
Adobe is a registered trademark of Adobe SystemsIncorporated
Ultrospec and GeneQuant are registered trademarks ofBiochrom Ltd.
Bluetooth is a registered trademark of the Bluetooth SIG
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Biochrom Ltd22 Cambridge Science Park,Milton Road, Cambridge CB4 0FJ UK
Tel: +44 (0)1223 423723Fax: +44 (0)1223 420164Email: [email protected]
www.biochrom.co.uk
Biochrom US84 October Hill Road,Holliston, MA 01746-1388 USATel: 877- BIO-CHROM (877-246-2476)
(Toll free)Fax: 508-429-5732
email: [email protected]
Distributors worldwide:
80-
7000-35
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