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leprosy pathogenesis epidemiology

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1 Leprosy Diana NJ Lockwood London School of Hygiene & Tropical Medicine Hospital for Tropical Diseases Leprosy in 2006 • Lepr osy is an in teres ting dis ease • Inter estin g mode l of tissu e damag e • Impo rtant d iagn osis not to miss • Rea dily tre atab le if diag nose d early • Particular problems of sen sory an d visual loss • Global challenge ©London School of Hygiene & Tropical Medicine Lepro sy- research • Path ogen esis of rea ctions and nerve d amage  – molecular mech anisms, using immunohistochemistry  – Effects of drugs on reactional pathology • Tre ati ng re act ion s  – Established immunosuppresants • azathioprine, cyclosporin, methylpredniso lone  – New drugs • Using M.leprae genome  – Strain typing India, Nepal, Ethiopia, London ©London School of Hygiene & Tropical Medicine

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Page 1: Leprosy Pathogenesis Epidemiology

8/10/2019 Leprosy Pathogenesis Epidemiology

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