lecture 9 muscles
TRANSCRIPT
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7/23/2019 Lecture 9 Muscles
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Photographs of the Child at the Ages of Six Days and SevenMonths (Panel A), Ultrasonograms (Panel B) and Morphometric
Analysis (Panel C) of the Muscles of the Patient and a Control
Infant, and the Patient's Pedigree (Panel D).
The arrowheads in Panel A indicate the protruding muscles of the
patient's thigh and calf. In Panel B, an ultrasonographic
transverse section (linear transducer, 10 MHz) through the
middle portion of the thigh reveals differences between the
patient and a control infant of the same age, sex, and weight. VL
denotes vastus lateralis, VI vastus intermedius, VM vastus
medialis, RF rectus femoris, and F femur. In Panel C, retracings
of the muscle outlines and results of the morphometric analysis
of the muscle cross-sectional planes of the two infants also reveal
marked differences. Panel D shows the patient's pedigree. Solid
symbols denote family members who are exceptionally strong,
according to information in their clinical history. Square symbols
denote male family members, and circles female family
members.
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Schuelke et al. (2004). Myostatin Mutation Associated with Gross
Muscle Hypertrophy in a Child.N Engl J Med350: 2682-8.
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