leading the way to a future without breast cancer a future without breast cancer a few words from...

2016 Report to the Community

Leading the way to a future without breast cancer

A few words from our CEO Lynne Hudson

I joined CBCF a year ago, captivated by the opportunity to maximize its powerhouse potential and make a life-saving difference to women in this country. The challenge was so compelling and I am tremendously proud of the actions we have taken during this transformative year.

This past year has been a time of transition and opportunity, setting the stage for pivotal developments that are changing the way breast cancer is understood, prevented, treated and experienced. Swift and sweeping change is never easy, but I believe our decisions strengthened CBCF in two ways:

We are working smarter. When our Board made the bold decision to make us one national entity, I was tasked with executing the consol-idation. Like many charities, we had been fragmented by different regional structures. Consolidation has achieved efficiencies to make the most of our donors’ dollars, so we can fund more world-class research and support more women. To combine four financial entities into one within a single year is an accomplishment that has been lauded by financial auditors.

After realistically assessing our business, we made choices for better efficiency and local delivery. We restructured and consolidated from four separate regions to one national entity headquartered in Toronto.

We are more supportive. With plans to consolidate with Willow Breast & Hereditary Cancer Support – an organization that offered psychosocial peer support and information programs – we took steps to support women throughout their experience with breast cancer. Breast cancer brings serious anxieties beyond fear: financial strain from lost income and expensive drugs and prosthetics; changes in family dynamics; and effects to a woman’s sense of self and well-being. The lack of psychosocial support for this emotional impact has been repeatedly noted as a gap in the system. Psychosocial care is recognized by clinicians and formally adopted in top hospitals. We are leading the charitable sector by funding treatments for aggressive breast cancers and by extending a human hand.

Our aim is to do everything we can to steward our precious donors’ dollars to fund more research and support more women. I am passionate about working harder and operating leaner than ever before to tackle breast cancer with a sharper head and a compassionate heart.

Lynne Hudson

Chief Executive Officer

2 CANADIAN BREAST CANCER FOUNDATION

The CBCF Board is different than any other. All members of this Board have been personally touched by breast cancer. Each of us is either a survivor or has had a loved one or friend who has died or endured years of compromised health following chemotherapy, radiation, mastectomy and other trials. We all share an urgent need to do more to help more women and men survive.

I am incredibly proud of the progress we have made over the past year. Our vibrant network of survivors and families has come together to volunteer, donate and fundraise to support our mission-related work. We have expanded our services even further; CBCF now touches the full spectrum of breast cancer – from the laboratory and clinic where the latest innovations are developed, to direct patient peer support.

So much has changed. When we first started the CIBC Run for the Cure back in 1992, we were the only organization hosting a race. Now the competition for donors is enormous. It became clear over the past year that CBCF would need to achieve more significant efficiencies, and we have been working hard to consolidate our efforts and promote ourselves more inventively.

The Board’s strategy to hire a National CEO rings in a new era in the Foundation’s history. Lynne Hudson, CEO, and the rest of her executive team have a great deal of experience in change management in the non-profit environment which bodes well as we consolidate activities and refocus priorities. Of course, all of our decisions and activities remain firmly rooted in our unwavering vision of creating a future without breast cancer.

We are confident that working together with all our stakeholders including the thousands of donors who support our efforts, we can continue to positively impact the lives of women touched by breast cancer. Overall, the feeling at CBCF is one of rejuvenation. It is a new workplace where people are positioned to focus on the areas in which they are best skilled. And that sets us up to be more successful in all that we do.

At the end of the day, our work is more than a matter of good governance. It is a matter of life and death. Everyone at CBCF is passionate about what they do as we know the work we fund helps save lives. That is why I am so grateful for the support of our many donors and why I plan to be committed to the organization for years to come.

Gail Rudderham Chernin, Q.C.

Chair, Board of Directors

A Message from our Board Chair Gail Rudderham Chernin, Q.C.

ANNUAL REPORT 2015/2016 3

About the Foundation

The Canadian Breast Cancer Foundation is a national community-driven charity. As the largest charitable funder of breast cancer research in Canada, CBCF’s vision is to create a future without breast cancer. Since its inception in 1986, the Foundation has invested over $360 million in breast cancer research, funding more than 1,400 scientific and community grants. CBCF’s investments in vital research, education, health promotion, support and information programs have led to progress in breast cancer prevention, diagnosis, treatment and care.

The Foundation is committed to our vision of creating a future without breast cancer and together, we can achieve it.

This Year’s Success in Numbers

allocated to scientific and community grants

volunteers across Canada

participants at the 2015 Canadian Breast Cancer Foundation CIBC Run for the Cure

new mobile digital mammography vans with thousands served

9,000VOLUNTEERS

3VANS

115,000PARTICIPANTS

$13.9MILLION


DIRECTORS Rob Assimakopoulos

Suzanne Bays

Joan Chambers

Robert Coard

Sue Delong

Shirley Forrest

Dr. Ruth Heisey

Dr. David Hoskin

Linda Humphreys

Dr. Jacques Magnan

Jodi Misheal

Don Pagnutti

Christy Teasdale

Leadership

OUR VALUED BOARD MEMBERS APRIL 1, 2015 TO MARCH 31, 2016

Gail Rudderham Chernin, Q.C. Chair

Valerie Steele First Vice-Chair

Lenora Gates Second Vice-Chair

Gord Gilroy Secretary

Susan Ewanick Past Chair

This Year’s Success in Numbers

grants and fellowship awards funded

social media impressions

4 regions consolidated into 1 national entity

visitors received breast health education at the

Pink Tour4,850

VISITORS

73AWARDS

1 ENTITY

64.5MILLION


The Stand Up To Cancer (SU2C) Canada - Canadian Breast Cancer Foundation Breast Cancer Dream Team, supported by CIBC, received a $9 million grant to fast-track urgently- needed new treatments targeting aggressive breast cancers – particularly triple negative breast cancer subtypes (TNBCs), which comprise 10 to 20% of all breast cancers.

Unlike chemotherapy, these new drugs are designed to distinguish cancer cells from healthy ones, minimizing harsh side effects. We are pleased to report that

one of the treatments being developed (called CX-5461) has gone to clinical trial. Exposure to this treatment in lab tests has reduced tumours in size and may also slow the growth of cancer, possibly killing cancer cells outright.

Led by Dr. Tak Mak at the University Health Network in Toronto and co-led by Dr. Samuel Aparicio of the University of British Columbia in Vancouver, the team includes some of Canada’s leading scientists from various disciplines who applied to our

research competition and were selected through a rigorous review process that involved world-class researcher reviewers.

The team is currently working to identify new biomarkers so treatments can become more personalized to each type of TNBC. Biomarkers are biological markers that signal a certain type of cell, or that are used to predict whether someone is likely to respond to a particular therapy, or whether their cancer is likely to recur and/or spread. These promising new treatments offer hope and may also help to reduce side effects like nausea and hairloss among people with aggressive breast cancers.

NEW THERAPY THAT SHRINKS TUMOURS GOES TO CLINICAL TRIAL

Research Achievements

BRINGING TOGETHER THE BRIGHTEST MINDS

“Important research initiatives like the one I have been involved in at St. Joseph’s Hospital save lives, but they require continual funding to do so. More research is needed

to study triple negative breast cancer and potential treatment therapies that could be used in the future. I’ve seen firsthand how research can benefit and save lives.”

— Montana M, London, Ontario

Triple negative breast cancer survivor

◆ 10-20% of women have triple negative breast cancer, which does not respond well to currently available treatments.

◆ Five-year survival rates tend to be lower for triple-negative breast cancer

◆ Triple negative breast cancer cells lack the three receptors (estrogen, progesterone, and human epidermal growth factor receptor 2) that are targeted by drugs like hormone therapy and Herceptin. Due to the lack of available targeted therapies, TNBC is treated primarily with surgery, radiation and chemotherapy.


“My first round of chemotherapy was so bad that I almost didn’t finish it. Studies like these will help people like me who are affected by chemo- induced nausea.”

— Star A, Halifax, Nova Scotia

FUNDING A GLOBAL FIRST – STUDYING CHEMO-INDUCED NAUSEA

Dr. Mark Clemons, a Medical Oncologist at The Ottawa Hospital and Clinical Investigator at the Ottawa Hospital Research Institute, has been working to reduce side effects from chemotherapy. Chemotherapy-induced nausea and vomiting can become so unbearable that it may compromise a person’s ability to tolerate what is potentially life-saving treatment.

Thanks to donor dollars, Dr. Clemons completed a study that evaluated a new risk prediction model to predict which patients were most likely to be affected by chemo-induced nausea and vomiting. The goal was to assess whether the anti-nausea drugs suggested by the model would reduce patient’s side effects more effectively than those that would have otherwise been prescribed by their physician.

The model proved to be superior to traditional approaches (i.e. physician chosen prescription). Given the importance of this work and its potential to improve the patient experience, Dr. Clemons has received a new CBCF grant to conduct a world-class study — the first of its kind — by applying this model to a larger group of patients with breast cancer undergoing chemotherapy.

Dr. Clemons’ hope is that, with further testing, this model could shape the future of cancer therapy globally by becoming incorporated into the standard of care for all people receiving chemotherapy.

Dr. Mark Clemons



“I was a 37-year-old single mother of one when I received a diag-nosis of Inflammatory Breast Cancer in 2012. Finding out that I was carrying BRCA2 gene mutation, it allowed me to get targeted treatments and even afterwards to undergo a preventive hysterec-tomy and oophorectomy. Because of research like Dr. Akbari’s, future treatments could be devel-oped to help treat breast cancers linked to this susceptibility gene muta-tion RECQL and save lives of other young women like me!”

— Julie M, Quebec City, Quebec

Dr. Mohammad Akbari

About 5 to 10% of all breast cancer cases are hereditary. Abnormal versions of genes (or gene mutations) that greatly increase breast cancer risk are passed on from parent to child within some families. Approximately half of the genes involved in these hereditary cases of breast cancer have been identified to date, the most common being the BRCA1 and BRCA2 genes.

CBCF-funded researcher Dr. Mohammad Akbari has discovered a new gene known as RECQL that may be involved in the development of hereditary breast cancer.

In collaboration with Canadian and Polish researchers, Dr. Akbari’s team found a strong link between RECQL mutations and breast cancer in a sample of Polish and French-Canadian women. These founder populations (populations which grew largely from expansion rather than through immigration) have limited genetic diversity, making it easier for researchers to identify disease-associated genes.

The findings, published in the journal Nature Genetics, may offer new insights into the prevention and treatment of hereditary breast cancer. If a woman is aware that she is at increased genetic risk for breast cancer, she can take steps to significantly reduce her risk. This discovery may also lead to the development of targeted treatments for breast cancer patients who have this gene mutation.


DISCOVERING A NEW BREAST CANCER SUSCEPTIBILITY GENE


NEW GENE TEST IDENTIFIES CANCER RISKS

Award-winning genomicist Peter Rogan, PhD, Canada Research Chair in Genome Bioinformatics, and his research team at Western University have developed a new way to identify gene mutations (abnormal changes) and identify which mutations are most likely to increase the risk of breast and ovarian cancers.

They sequenced 20 complete breast cancer genes and developed new computerized methods to analyze mutations. Their results have added several pieces to the puzzle that is determining which mutations (there are many) can cause cancer and which ones are harmless.

Dr. Rogan’s approach is revealing gene variations that could help many women explain their increased risk for cancer and help save countless lives.

Dr. Peter Rogan

For as long as I can remember, the Run has been part of CIBC’s culture. Our commit-ment to the Canadian Breast Cancer Foundation started over 20 years ago and continues to grow because our team cares deeply about creating a future without breast cancer. CIBC is so proud to be part of this trail-blazing partnership with CBCF and the thousands of donors, participants, partners and volunteers across the country in helping to change the face of breast cancer in Canada.

The CIBC Run for the Cure is a movement that brings loved ones together to support life-saving research that has the potential to improve breast cancer care, treatment outcomes and survivorship. We know more women are surviving and in fact, breast cancer mortality rates have decreased by 44 percent since the late 1980s due to earlier

detection through regular mammography screening, advances in screening technology, and improved treatment options. Imagine what we can achieve in the years to come!

Each year on Run Day, I am struck by the energy bursting from Team CIBC as we come together, united by a common goal – a future without breast cancer. A sea of red and pink shirts proudly displaying the names of loved ones being honoured, gives me great pride to know that we are all Changemakers, when we run.

Thank you on behalf of CIBC for your support of the Canadian Breast Cancer Foundation – together we will create a future without breast cancer.

Christina Kramer

Executive Vice-President & Team CIBC’s Executive Run Sponsor


Earlier Detection

PUTTING WOMEN IN CHARGE OF THEIR BREAST HEALTH

MY BREASTS, MY TEST

Supporting women to make informed choices about mammography

There are many questions women ask when they start to think about having a mammogram. Mammography is an effective way to find breast cancer early, yet many eligible Canadian women still do not screen regularly.

This year, CBCF launched My Breasts, My Test, a national tool designed to assist women in making an informed decision about mammography. This user-friendly decision aid outlines the bene-fits and limitations of mammography, describes breast cancer risk factors and informs women on what to expect and how to prepare for test day.

My Breasts, My Test can be found online at cbcf.org/mytest and provides a personalized screening guide to women who provide their age, province and screening history.

What’s it like?

Why get one?

Are they safe?

Am I at risk?


SHOPPERS DRUG MART BEAUTY GALAS

Shoppers Drug Mart Beauty Boutiques hosted two Beauty Galas in British Columbia and Ontario, offering free makeovers, skin consultations, giveaways, samples and refreshments. Proceeds from ticket sales helped fund digital MammoVans and CBCF’s online mammography decision aid tool My Breasts, My Test. Beauty Galas are just one of the many ways Shoppers Drug Mart helps women honour and care for themselves while supporting CBCF.

MammoVan launch at Vancouver’s Musqueam Community Centre, where Musqueam elders and leaders blessed the coaches to lend strength to women facing breast cancer.

The Canadian Breast Cancer Foundation joined forces with Shoppers Drug Mart and the BC Ministry of Health Screening Mammography Program to help make a meaningful difference in the lives of Canadian women.

As part of this pilot project, we launched three new state-of-the-art mobile digital MammoVans that toured British Columbia, making it easier for women in remote, rural or high-density urban settings to get screened.

Currently, the coach vans provide 33,000 mammograms a year to Canadian women using wireless technology that ensures faster delivery of results.

DIGITAL MAMMOVANS

Driving Women’s Health Forward


Touring the country since its launch in 2009, the Pink Tour returned to Atlantic Canada this year in partnership with Shoppers Drug Mart and CIBC.

Travelling across the Atlantic provinces, the new Pink Tour minivans were equipped with interactive pop-up displays and bilingual ambassadors who hit

the road to prompt women (and men) to reduce their risk of developing breast cancer by making lifestyle changes. We know that adopting healthy lifestyle changes, such as reducing alcohol intake, adopting a healthy weight through physical exercise and a healthy diet can contribute

to overall health and reduce the risk of developing breast cancer.

Through this interactive tour, CBCF engaged and encouraged over 4,800 individuals to have conversations about living well and reducing their risks for breast cancer.

Earlier Detection

THE PINK TOUR

Driving Home to Atlantic Canada (and raising awareness along the way!)


CBCF AMBASSADOR PROGRAM

Supporting Women to Make a Difference in Their Communities

The CBCF Breast Health Ambassador Program was piloted this year in Ontario with the aim of providing women with the tools they need to start conversations about breast health and screening in their communities.

Current ambassadors represent a wide range of professions and speak a combined 11 languages.

By developing and sustaining personal connections to community organizations, ambassadors target underserved areas where women need greater awareness and understanding about breast health and breast screening.

How do you promote breast cancer awareness among women whose language has no word for cancer? There is no direct translation for cancer in Cree, Ojibwe, Dakota, nor Oji-Cree – these First Nations simply use phrases such as “the great sickness.” A need to increase breast cancer awareness amongst these communities was apparent.

Thanks to a CBCF grant to Cancer Care Manitoba’s Breast Check program, women from various First Nations communities spear-headed a solution by pooling their resources to help build a culturally-appropriate toolkit to promote breast cancer awareness and screening. Six women from Thompson, Manitoba led the project to tailor the toolkit to First Nations women and make it available in five indigenous languages.

The toolkit included a flipbook about prevention for educators, a breast model, wooden beads to indicate various tumour lump sizes, an educational DVD for healthcare waiting rooms, and a brochure about mammography.

Every Aboriginal community throughout Manitoba now has a copy of this important toolkit. This groundbreaking project is bringing women together and facilitating much- needed conversations about breast health and screening.

CHAMPIONING TAILORED LEARNING TO MEET THE NEEDS OF FIRST NATIONS WOMEN


Community Support

There’s nothing that brings communities together like a little friendly competition. Batting Against Breast Cancer, an annual, family-friendly slo-pitch tournament literally ‘takes a swing’ at breast cancer and has raised over

$3.4 million for breast cancer research and awareness projects to date.

This year, the tournament took place in Winnipeg, Regina, Red Deer, Calgary and Edmonton, pitting 96

teams (that’s over 1,250 participants) against one another in more than 300 games. An amazing $407,056 was raised this year through donations, sponsorships and raffle ticket sales.

BATTING AGAINST BREAST CANCER

Communities Stepping Up To the Plate

RALLYING TOGETHER TO MAKE A DIFFERENCE


KITCHENAID® COOK FOR THE CURE CULINARY SHOWDOWN

Firing Up the Stove to Support CBCF

What do you get when you combine top Canadian chefs with foodies who want to create a future without breast cancer? The Canadian Breast Canadian Foundation KitchenAid® Cook for the Cure Culinary Showdown!

This unique event gave culinary enthusiasts the opportunity to fundraise for a chance to cook alongside and learn from an all-star lineup of celebrity chefs. Top fundraisers earned a

chance to compete on the teams of celebrity chefs Lynn Crawford, Elizabeth Falkner, Ricardo, Marcus Samuelsson and Corbin Tomaszeski. The chefs were assigned mystery ingredients at the last minute and charged with creating recipes using the ingredients in novel and exciting ways.

Through the support of donors and participants, the third annual Culinary Showdown raised an extraor-dinary $758,000. Since 2002, KitchenAid® has been a partner of CBCF and has raised over $3.9 million through the Cook for the Cure program.

KISS2CURE

Uniting CBCF and Prostate Cancer Canada in an Unprecedented Collaboration

Breast and prostate cancers are two of the most common cancer threats to women and men, so CBCF teamed up with Prostate Cancer Canada for Kiss2Cure, a ground-breaking national, social media-based, interactive charity partnership.

One month leading up to Valentine’s Day, Canadians were asked to share their best kiss using the hashtag #Kiss2Cure and to make an online donation towards life-saving research on both cancers.

Thousands of amazing kiss photos poured in to a dedi-cated Facebook page and website. Newborns, pets and even some high-profile politicians got in on the action to raise funds for breast and prostate cancer research.


National Corporate Partners

FORGING ENDURING RELATIONSHIPS

Kruger’s White Cashmere Collection is a Canadian celebration that unites Cashmere Bathroom Tissue, Canadian fashion designers and the Canadian Breast Cancer Foundation. A much anticipated, annual fund- and awareness-raiser for CBCF, the collection is produced by Kruger Products L.P., maker of Cashmere Bathroom Tissue, one of the Foundation’s top five national brand partners and proud supporter since 2005.

This year’s show, featuring the world’s first collection of one-of-a-kind, designer-made wedding couture fashioned from luxuriously, soft sheets of Cashmere BT, took place at The Carlu in Toronto, heralding the annual return of limited-edition Pink Cashmere – 25 cents from each package sold (up to a maximum of $35,000) goes to CBCF during Breast Cancer Awareness Month in October. Canadians were invited to vote for their favourite bridal couture and Cashmere donated $1 for every vote (up to $10,000) to CBCF in the winning designer’s name.

KRUGER PRODUCTS’ COMMITMENT TO THE CAUSE


UNDER ARMOUR POWER IN PINK PUMPED UP

Under Armour, makers of high-performance sports apparel, has committed to support breast health for young women through education, outreach and research. By funding Breast Health Living Well Workshops, they are supporting the education and engagement of people across Canada in workplace settings, community health centres and places of worship.

Under Armour also provided funding to the Pan-Canadian Research Project for Breast Cancer in Young Women, one of the largest grants ever seen in Canada to study breast cancer in young women under 40. The research team will study 1,200 women over four years, looking at lifestyle factors, fertility, genetic mutations, optimal treatments, and stress reduction strategies.

WESTJET 2015 NATIONAL SPONSORSHIP TOOK FLIGHT

WestJet certainly went the distance for CBCF this year by generously providing over 100 domestic one-way vouchers to be used by the Foundation. This helped to offset travel costs associ-ated with the CIBC Run for the Cure volunteer director training and on-site event support. In addition to this donation, WestJet also donated 25 fund develop-ment flight vouchers (100 one-way tickets to anywhere WestJet flies) that were used by CBCF for national and regional fundraising and incentives. To top this off, nearly 430 WestJet employees rallied their fami-lies and friends to participate in the 2015 CIBC Run for the Cure in their 17 home cities across Canada raising funds to help create a future without breast cancer.

PEPSICO INSPIRED HOPE AT THE CIBC RUN FOR THE CURE

As we celebrated our sixth year of partnership at the CIBC Run for the Cure this October, PepsiCo Canada brought tremendous energy, passion and commitment as our Official Beverage Sponsor. Through their support, PepsiCo Canada delivered corporate sponsorship, product support and – most important of all – an integrated engagement and fundraising commitment through its team of employees and their families across the country.

With 716 participants across 44 sites, PepsiCo Canada’s employee team raised over $195,000 and, was once again, the second-largest and second-highest fundraising Corporate Run Team. It’s not surprising they won the Corporate Spirit Award in Sherbrooke, QC, Moncton, NB and London, ON. PepsiCo Canada also refreshed Run participants by generously donating juices and water at Run sites across the country.


CBCF NATIONAL REVENUE

59.0% CIBC Run for the Cure

25.7% Individual and Corporate Gifts

14.0% Fundraising Events

1.3% Other Revenue

15.8% Operations

31.7% Fund Development

52.5% Research and Grants Cause Related Spending

CBCF NATIONAL EXPENSES

For a full financial report, visit: cbcf.org/central/AboutUsMain/Financials

Financial Stewardship

A SUMMARY OF THE YEAR ENDING MARCH 31, 2016

ALLOCATIONS

SOURCES


In 2016, we paved the way to merge with Willow Breast & Hereditary Cancer Support. Since 1994, Willow has focused on providing emotional support and information to anyone affected by breast cancer or at increased genetic risk of the disease – from the individual diag-nosed to their family, friends and caregivers. These vital services will continue to be offered to all Canadians through CBCF – and ultimately expand in their reach.

No one understands the impact a breast cancer or high-risk diagnosis can have on your life as well as someone who has experienced it herself – a peer. Callers to a dedicated CBCF helpline will speak with a member of our Support and Information Services Team – a woman who has had a breast cancer or high-risk diagnosis and is specially trained to provide support and information. The team works with CBCF’s health librarian to provide individuals with the most current and credible information that best meets their needs and preferences.

The caring members of our team can relate to a caller’s concerns, share their personal

experience, and offer hope and encour-agement. They help reassure others that they are not alone in what they are experiencing, normalize difficult emotions, dispel fears and myths, and share valuable coping skills. The team

has a broad and up-to-date understanding of the many issues related to breast cancer and can answer many questions a client may have.

“You do not need a doctor’s referral. There is no time limit. Just pick up the phone and call,” says Linda, manager of CBCF’s Support and Information Services Team. “We can direct you to further resources, help you navigate the healthcare system and suggest what questions to ask your healthcare team.”

Because each person’s experience is unique, CBCF’s support and information services are personalized to each individual. We can address a range of questions and concerns related to breast health concerns, risk management, diagnosis, treatment, survivorship, as well as the specific needs of those living with metastatic breast cancer. An interpreter service is also available for anyone whose first language is not English and wishes to access our helpline in their native language.

As a breast cancer survivor, Linda knows firsthand the emotional toll that breast cancer can take on your life and how helpful it can be to connect with someone who really understands what you may be going through. “Callers may have many questions or they may simply need to speak to someone who can relate to their concerns,” she says. “We give people a safe space to freely voice their feelings and ask their questions. We are here to help make their journey a little easier with every step along the way.”

We’re Here to Help Because We’ve Been ThereCBCF SUPPORT AND INFORMATION SERVICES

Call our helpline at 1.888.778.3100 (toll-free anywhere in Canada). You can also send your questions to

[email protected] or visit support.cbcf.org for more information.


301-375 University Avenue Toronto, Ontario M5G 2J5

T 416.596.6773 TF 1.800.387.9816

cbcf.org

SEE THE FULL REPORT CBCF.org/2016CommunityReport

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leading the way to a future without breast cancer a future without breast cancer a few words from...

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