léčba aneurysmat, avm, kavernomů · small aneurysm -wide neck -mca -failure of evt (10%) limit...

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čba aneurysmat, AVM, kavernomů Sameš M., Hejčl A., Vachata P., Bartoš R., Pavlov V., Cihlář F., Derner M. Neurosurgical Department, Department of Radiology, Masaryk Hospital, Ústí nad Labem, Czech Republic

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Page 1: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Léčba aneurysmat, AVM, kavernomů

Sameš M., Hejčl A., Vachata P., Bartoš R., Pavlov V., Cihlář F., Derner M.

Neurosurgical Department, Department of Radiology, Masaryk Hospital, Ústí nad Labem, Czech Republic

Page 2: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

SAH Management Coil Clip Higher age, ASA risk Younger ageBrain edema, HH 4-5

Location-post circ (post inf BA) Location-ant circ (MCA)Size 2-7 mm Size > 7 mmNeck (5/2 = fundus/neck) Wide, complex neck

ICH, hydrocephalus, FisherKink, atherosklerosis

Symptomatol (CN III)

experience surg x endovascopinion of pts

Page 3: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:

- giant (5%)- small aneurysm (5%)- wide neck (10%) - MCA ( 25%)- failure of EVT (10%)

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 4: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Giant aneurysms

Dept. NeurosurgeryÚstí nad Labem

Page 5: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Case report – trap M2+bypass

Dept. NeurosurgeryÚstí nad Labem

Page 6: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Case report - postop

Dept. NeurosurgeryÚstí nad Labem

Page 7: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:

- giant- small aneurysm < 2 mm (5%)- wide neck- MCA- failure of EVT

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 8: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 9: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:

- giant- small aneurysm- wide neck (5%)- MCA- failure of EVT

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 10: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 11: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:

- giant (5%)- small aneurysm (5%)- wide neck (5%) - MCA ( 25%)- failure of EVT (10%)

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 12: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 13: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:

- giant- small aneurysm - wide neck - MCA - failure of EVT (10%)

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 14: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 15: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 16: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

BOT

Carotid-opthalmic aneurysmsBOT, superior direction, TCD, suction blood from CCA

Page 17: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Opthalmic aneurysm-CT postop

Page 18: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

MRA postop-no residual neckPerimeter intact, no neurol deficit

Page 19: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Dept. NeurosurgeryÚstí nad Labem

Uncoilable aneurysms:- giant (5%)- small aneurysm (5%)- wide neck (10%) - MCA ( 25%)- failure of EVT (10%)

- ----------------------------------------------------- uncoilable 55%

Limit and Benefit Endovascular vers. Mininvasive surgery

Page 20: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Advances of surgeryHernesniemi Prague 2007

1. CTA2. Approaches – simple, fast3. Killing the aneurysms4. Navigation, 3D models5. Intraoperative AG (ICG)6. Prevention of vasospasms – Nicardipine – release

pellets7. Bypass – surgery, selana, elana, strip8. Subspecialization9. Strong experience – video, courses, education

Page 21: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Intradural drilling of ant clin proc carotid opthalmic aneurysm

Page 22: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Summary of isolated dissecting PICA aneurysm: Location

Anterior medullary segment 38%Lateral medulary segment 27%Tonsilomedullary segment 9%Telovelotonsilar - perfor to BG 9%Cortical segment 13%

Korematsu K.et al., Acta neurochirurgica 150: 77-81, 2008

Page 23: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 24: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 25: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 26: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 27: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Postop DW MRI

Page 28: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Postop – approach, clip, follow up 6 months

Page 29: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Follow up studyaneurysm a.basilaris - coil

Page 30: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

recanalization after 6 months, recoil

Page 31: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

clipping

Dept. NeurosurgeryÚstí nad Labem

coiling

75% 25%

Page 32: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

MNUL UVN Homolka LBC

klip 63 33 35 24

coil 21 66 37 2

celkem 84 99 72 26

Počet ošetřených aneurysmat na vybraných pracovištích, 2010

Page 33: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

AVM

Page 34: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Léčba AVM

Page 35: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Léčba AVM - LGK

rok % obliterace

1 20%2 60%3 70%4 80%

Spetzler- MartinLGK Homolka

Gr 1 12%Gr.2 49%

Page 36: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Kavernózní angiom

1. Supratentoriální – epilepsie, krvácení2. Kmen mozkový

- dotyk s pia mater- recididivující krvácení

LGK neúčinný, pokud léčba - resekce

Page 37: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

T.E., 45, kolapsové stavy, hemihypestézie

Page 38: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 39: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Pooper CT, bez komplikací

Page 40: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

V.R., 59, recidivující krvácení z kavernomu, LGK bez efektu

Page 41: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms
Page 42: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Po operaci bez okohybné poruchy

Page 43: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

F.M, 85, bolesti hlavy, Parinaud, diplopie, na CT/MR hematom v tectu, kavernom

Page 44: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Pooper kontrola 4/11

Page 45: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

Pooper kontrola 4/11

Page 46: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

j.o., 70, diplopie vertigo, v době termínu na operaci recidiv krvácení s hemiparézou a plegií VII dx, oper 12/08

Page 47: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

3/09 pooper kontrola

Page 48: Léčba aneurysmat, AVM, kavernomů · small aneurysm -wide neck -MCA -failure of EVT (10%) Limit and Benefit Endovascular vers. Mininvasive surgery. BOT. Carotid-opthalmic aneurysms

MNUL Poruba UVN Homolka HK Plzeň LBC

2669 2642 2640 2433 2027 1641 1568

Neurochirurgická klinika MN UL 1968 - 2010