To create an open access, integrative bionetwork evolved by contributor scientists working to eliminate human disease.

Sharing: Disease biology is too complicated to be solved by any one group using one dataset. Collaboration: Science is most successful when smart people with varied expertise come together to solve a problem.

Lara Mangravite, PhD

transcriptional network

protein network

metabolite network

ENVIRO

NMEN

T  Non-coding RNA network

Data1   Results1   Model1  

Data2   Results2   Model2  

Community Opinion Collaborative Research

Biological and

Clinical Validation

An open source, community-based genomic compute space: Synapse

Platform Launch: Fall 2011

Think Global, Act Local!

2011 partner projects:

Amgen: Biomarkers of drug-induced liver toxicity

Seattle Children’s Hospital: Mechanisms for development of craniosynostosis

Presage Biosciences: Drug targets for prostate cancer

Collaborations are funded through a grant from:

The Washington Partners Program: Improve biomedical research in WA through research

partnerships

2012 Partners Proposals October 1st 2011

www.sagebase.org/wpp