AGEING PROCESS IN

THE EYE HABIBAH S. MUHIDDIN

DERMATOCHALASI (BLEPHAROCHALASIS)

CORNEAL ARCUS

SENILE CATARACT

AGE RELATED MACULARDEGENERATION(AMD)

LEADING CAUSE OF IRREVERSIBLE BLINDNESS IN OLD PEOPLE

CLASSIFICATION :

DRY TYPE AND WET TYPE

DRY TYPE : DRUSENWET TYPE : - EXUDATIVE RPE - DETACHMENT - NEOVASCULAR STAGE

INTERNATIONAN CLASSIFICATION BASED ON CLINICAL MANIFESTATION: * EARLY AMD : DRUSEN * LATE AMD : GEOGRAPHIC ATROPHY NEOVASCULARSTAGE

DRUSEN

LATE AMD WITH EXUDATE AND NEOVACULARISATION

RETINAL PEGMENT EPITHELIUMSPECIALIZED FUNCTION TO SUSTAIN THE PHOTORECEPTOR CELLS AND OUTER SEGMENT RENEWAL

TO DISCHARGE CYTOPLASMIC MATERIAL TO THE INNER PORTION OF BRUCHS MEMBRANE TO ACHIEVE CYTOPLASMIC RENEWAL

RPE CHANGES WITH AGE ARE CHARACTERIZED BY THE ACCUMULATION RESIDUAL BODIES (CONTAIN LIPOFUSCIN) IN RPE CYTOPLASMIC

BRUCHS MEMBRANE

LOCALISED BETWEEN RPE AND CHORIOCAPILLARIS (CC)

PROVIDES A SEMIPERMEABLE FILTRATIONBARRIER THROUGH WHICH MAJOR METABOLIT EXCHANGE TAKE PLACE CC --- NUTRIENT (THROUGH MB, RPE) -----PHOTORECEPTOR PR CELLULAR BREAKDOWN PRODUCT (RPE, MB) --CC

DRUSEN

GEOGRAPHICATROPHY

NEOVASCULAR DEVELOPMENT

TREATMENT

*NO T/ FOR DRY OR EARLY AMD

*LASER PHOTOCOACULATION PDT (PHOTODYNAMIC TH/) TTT TRANSPUPILLAY THERMO TH/)