Kratom & Kratom History

History

Kratom had recently been documented since 2004 and 2005 when it stepped into the spotlight inWestern and for medical research on its application in different fields. However, the studies doneare still not published. Many countries do not recognize this, and it is mostly illegal. Today, theinternational legality of Kratom is uncertain, although there are many advantages that have beenseen. The first mention and documentation of Kratom was in the 19th century by a botanist calledPieter Willem Korthals who documented its use as a substitute for drugs like opium taken indifferent methods such as chewing and as concoction.

The Active Ingredients

Scientists say that mitragynine accounts for 70% of various active alkaloids in Kratom. There areother minor indole alkaloids that have been identified such as speciogynine, paynantheine,rhynchophylline, and speciociliatine. There is no clinical research that shows that its leaves producethe hallucinogenic effects. However, the animal studies show that interaction with Kratom is notconfined to the opiate receptors. There is an element in this herb that is not accounted for which isknown to interact with adrenergic and serotonergic systems.

Early Research

The United Nations published an earlier report describing Kratom as having alkaloids. During anexperiment on animals, it was found out that its long-term uses on the experimental animals reducedthe intake of food and water. In the end, these animals did not develop tolerance to the effects.

Today, there is no open information detailing the Kratom usage in the U.S. This cannot be detectedby any present immune screening systems used to test the use in the laboratories. Today, it is notknown in the U.S whether mortality or morbidity has resulted from green malaysian kratom usage.However, there are extensive materials on the internet showing how people have abused it indifferent forms.

Considerations

There is little information known about the human pharmacology or the toxicology of this ancientThai herb. But with people getting to read on internet sites, it can lead to abuse. Various Vitrostudies show convincingly that it contains mitragynine and other elements, which have become

potent opiate agonist. In fact, this, according to research can produce analgesia. Research hasshowed that the 7-hydroxymitragynine metabolites are more potent than the morphine.

Medical Research

Kratom has shown that it has a vast medical potential during medical research. It has shown to be apowerful analgesic. According to the Botanical legal defence newsletters, it is argued that thecurrently reviewed studies on Kratom and the constituent shows that it lacks acute toxicity, showspowerful antioxidant and the antibacterial properties. Clinical statistics shows that this herb can beapplied to help in alcohol withdrawals. It is rich in oxindole alkaloid that shows potent modulationproperties. It also contains constituents that have shown anti-cancer properties. Doing research onpeer-reviewed articles and clinical trials shows the medical potential of Kratom. In short, studieshave shown that there are no significant safety issues to the health of human when applied as amedication.

Legality Issue

To many people, Kratom is legal to use, grow and posses in various European Union countries andthe U.S.A. For any person who comes across it, they have to take responsibility to check whether itis classified as legal or illegal in their country. From website sources, however, many countries havebanned Kratom. These include Denmark, Malaysia, Sweden, Thailand, Burma, Australia, Lithuania,Vietnam, Myanmar, Poland and Finland.

In fact, Kratom was banned in its country of origin. The Thai government banned it first in 1943.Therefore, any person who plants the tree is forced to cut it down. The law was found to be faultybecause this tree was one of the indigenous plants in Thailand and can lead to a long jail term whenfound in possession. With the prohibition in Thailand, it has seen its black market prices jump to anall-time record.