kastelein jj, et al. circulation 2008;117:3002-9 on-treatment values of lipids, apolipoproteins, and...

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Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

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Page 1: Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Kastelein JJ, et al. Circulation 2008;117:3002-9

On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Page 2: Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Individual Relationships Between On-Treatment Levels of LDL Cholesterol, Non-HDL Cholesterol, Apolipoprotein B,

or Their Ratios and MCVEs in TNT and IDEAL

Kastelein JJ, et al. Circulation 2008;117:3002-9

Page 3: Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Direct Pairwise Comparisons of the Relationships With

MCVEs for On-Treatment Levels of LDL Cholesterol,

Non-HDL Cholesterol, Apolipoprotein B,

or Their Ratios in TNT and IDEAL

Kastelein JJ, et al. Circulation 2008;117:3002-9

*Calculated by a Cox proportional hazard model with adjustment for the effects of study, age, and sex.†Calculated as total cholesterol minus HDL cholesterol.

Page 4: Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Individual Relationships Between On-Treatment

Levels of LDL Cholesterol,

Non-HDL Cholesterol, Apolipoprotein B, or Their Ratios and MCVEs in Selected

Subgroups of TNT and IDEAL

Kastelein JJ, et al. Circulation 2008;117:3002-9

*Calculated by a Cox proportional hazard model with adjustment for the effects of study, age, and sex.†Calculated as total cholesterol minus HDL cholesterol.

Page 5: Kastelein JJ, et al. Circulation 2008;117:3002-9 On-Treatment Values of Lipids, Apolipoproteins, and Their Ratios in Both Treatment Groups of TNT and IDEAL

Kastelein JJ, et al. Circulation 2008;117:3002-9

CLINICAL PERSPECTIVE