k.53 male contraception

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    MALE CONTRACEPTION

    Urology Division, Surgery Department

    Medical Faculty,

    University of Sumatera Utara

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    MALE CONTRACEPTION

    male contraceptive method :

    - condoms

    - periodic abstinence

    - withdrawl

    Typical 1st-year failure rates :

    - withdrawl 19%

    - periodic abstinence 20%

    - condoms 3 14%

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    Thin sheaths of rubber, vinyl or natural

    products which may be treated with a

    spermicide for added protection. They are

    placed on the penis once it is erect

    Condoms deiffer in such qualities as shape,

    color, lubrication, thickness, texture and

    addition of spermicide (usually nonoxynol-9)

    Definition

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    Types

    Latex (rubber)

    Plastic (vinyl) Natural (animal products)

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    Research :

    - prevent sperm production (use of androgen,

    progesteron, GnRH)

    - interfere with the ability of sperm to mature andcarry out fertilization by using an epididymal

    approach to create a hostile environment for

    sperms

    - produce better barrier methods

    - produce of antisperm contraceptive vaccine

    - inhibit sperm-egg interactions

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    Use of existing male

    contraceptives in developed

    region

    Use of existing male

    contraceptives in developing

    region

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    Hormonal male contraception

    Based on suppression of gonadotrophin & the use

    of testosterone substitution to maintain male

    sexual function & bone mineralization & to prevent

    muscle wasting Research :

    - testosterone monotherapy

    - androgen/progestin combination

    - testosterone with GnRH analogues

    - selective androgen and progestin receptor

    modulation

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    VASECTOMY

    Is an effective method of permanent male

    surgical sterilization

    Before the procedure, the couple should be

    given accurate information about the benefit &risks

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    Surgical techniques

    various techniques

    no-scalpel vasectomy the least invasive

    approach to the vas

    cauterization of the lumen of the vas &

    fascial interposition most effective

    occlusion technique

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    Complications

    Acute local complications :

    - haematoma, wound infection, epididymitis

    5% cases

    Long term complications :

    - chronic testicular pain, epididymal tubal

    damage

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    Vasectomy does not significantly alter

    spermatogenesis & Leydig cell function

    Volume of ejaculate unchanged

    Rate of prostate cancer could not increased

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    Vasectomy failure

    Effective occlusion technique risk of

    recanalization < 1%

    No motile spermatozoa 3 mo later

    Persistent motility sign of vasectomy

    failureneed to repeat the procedure

    Long term recanalization may occur (rare)

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    Counseling

    It should be considered irreversible

    It has a low complication rate. However,because vasectomy is an elective operation

    even small risks should be explained as menmay wish to consider these before giving theirconsent

    It has a low, but existing, failure rate

    Couples should be advised to continue withother effective contraception until clearance isachieved

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    All available data indicate that vasectomy is

    safe & not associated with any serious, long

    term side effect

    Fascial interposition & cauterization seem togive a higher efficacy

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    Vasectomy reversal

    Success rate > 90%, depend on :

    - the time elapsed after vasectomy

    - type of vasectomy (open ended or sealed)

    - type of reversal (vasovasostomy or

    vasoepididymostomy)

    - unilateral or bilateral

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    The most cost-effective approach to treatment

    of post-vasectomy infertility is microsurgical

    reversal. This also has the highest chance of

    delivery

    Couples can have a family after successful

    vasectomy reversal. There is no need for

    hormonal treatment of the female partner, withits associated risks of ovarian hyperstimulation

    and multiple pregnancies

    Conclusions