ivms intro to biochemistry lecture 17 -carbohydrate metabolism

8/13/2019 IVMS Intro to Biochemistry Lecture 17 -Carbohydrate Metabolism

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Ebkachobstry 9:JHLHUI@ WUBLABW@HQ

Airekcynrith Ohtiek`bso

9

Wrhpirhn iln prhshlthn ey

Oira Bockthp Ariy, O.N.Eisba Ohnbai` Qabhlahs & AD ^hiachr

Uhfhrhlah rhskurah=

Airekcynriths-Zbdbphnbi
http://en.wikipedia.org/wiki/Carbohydrateshttp://en.wikipedia.org/wiki/Carbohydrateshttp://en.wikipedia.org/wiki/Carbohydrateshttp://en.wikipedia.org/wiki/Carbohydrateshttp://www.imhotepvirtualmedsch.com/


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Quooiry

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Bltrknuatbkl iln Nbjhstbkl kfAirekcynriths.Jùaksh bs tch dhy fkknok`hau`h fkr okst krjilbsos, iln bt bstch ahltri` suestilah bl airekcynrithohtiek`bso. Nurblj nbjhstbkl,airekcynriths irh cynrk`yzhn tk tchoklksiaacirbnhs jùaksh, fruatksh, ilnjiìatksh, wcbac irh ieskrehn bltk tche`kknstrhio tcrkujc tch `blblj kf tchsoi`` blthstblh.

E`kkn Jùaksh.Jùaksh bs tch okstieulnilt airekcynrith bl tch e`kkn. ^ch`bvhr rhjuìths e`kkn jùaksh `hvh`s sktcit i suffbabhlt aklahltritbkl bs i`wiysivibìe`h tk ohht tch ekny's hlhrjy

lhhns. I `kwhr tcil lkroi` e`kkn jùaksh`hvh` bs rhfhrrhn tk is cypkj`yahobi,wchrhis i cbjchr tcil lkroi` e`kknjùaksh `hvh` bs throhn cyphrj`yahobi.

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J`yak`ysbs.J`yak`ysbs, i shrbhs kf thl rhiatbklstcit kaaur bl tch aytkpìso, bs i prkahss bl wcbacklh jùaksh ok`hau`h bs aklvhrthn bltk twkok`hau`hs kf pyruvith. ^wk ok`hau`hs kf I^W ilntwk ok`hau`hs kf LINC irh prknuahn bl tch

prkahss. Ektc jiìatksh iln fruatksh irh aklvhrthnbltk blthrohnbith tcit hlthr tch j`yak`ysbs pitcwiy.^ch j`yak`ysbs pitcwiy bs akltrk``hn ey tchrhjuìtbkl kf tcrhh dhy hlzyohs bl tch rhiatbklshquhlah.

Fiths kf Wyruvith.Wyruvith, tch prknuat kfj`yak`ysbs, cis tcrhh nbffhrhlt fiths. Xlnhr ihrkeba

aklnbtbkls, pyruvith hlthrs obtkacklnrbi iln bsaklvhrthn tk iahty` AkI. ^ch iahty` AkI hlthrs tchabtrba iabn aya`h. prknuats kf tch abtrba iabn aya`hhlthr tch h`hatrkl trilspkrt acibl wchrh kxbnitbklbs akop`hthn iln I^W bs syltchsbzhn. I shakln fithkf pyruvith bs aklvhrsbkl tk ìatith. ^cbs tidhspìah bl ilihrkeba obarkkrjilbsos iln bl kur kwleknbhs wchl j`yak`ysbs kaaurs fisthr tcil tchkxyjhl nhphlnhlt abtrba iabn aya`h iln h`hatrkltrilspkrt acibl ail kphrith. Qkoh obarkkrjilbsosaklvhrt pyruvith tk htcilk`, tch tcbrn fith kfpyruvith. bl hiac kf tchsh tcrhh prkahsshs, LIN+bs rhjhlhrithn sk tcit j`yak`ysbs ail akltbluh.

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^ch Abtrba Iabn Aya`h.^cbs pitcwiy aklsbstskf hbjct rhiatbkls tcit prkahss blakobljok`hau`hs kf iahty` AkI. ^ch airekl itkos`hivh tch aya`h bl tch fkro kf ok`hau`hs kfAK5. ^ch cynrkjhl itkos iln h`hatrkls `hivhtch aya`h bl tch fkro kf rhnuahn akhlzyohsLINC iln FINC5. ^ch aya`h bs rhjuìthn eytcrhh i``ksthrba hlzyohs bl rhspklsh tkah`ùìr `hvh`s kf I^W. Klh iahty` AkI ok`hau`hhlthrblj tch abtrba iabn aya`h prknuahs tcrhhok`hau`hs kf LINC, klh kf FINC5, iln klh kfJ^W.

^ch H`hatrkl ^rilspkrt Acibl.^cbspitcwiy blvk`vhs i shrbhs kf rhiatbkls tcitpiss h`hatrkls frko LINC iln FINC tkok`hauìr kxyjhl. Hiac airrbhr bl tch shrbhscis il blarhisblj iffblbty fkr h`hatrkls. Fkurkf tch airrbhrs, wcbac irh rhfhrrhn tk is

aytkacrkohs, akltibl brkl, wcbac iaahpts ilntchl trilsfhrs tch h`hatrkls. Is LINC ilnFINC5 rh`hish tchbr cynrkjhl itkos ilnh`hatrkls, LIN+ iln FIN irh rhjhlhrithn fkrrhturl tk tch abtrba iabn aya`h

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J`yakjhl Ohtiek`bso.Zchl e`kkn jùaksh`hvh`s irh cbjc, hxahss jùaksh bs aklvhrthnbltk j`yakjhl ey tch prkahss kf j`yakjhlhsbs.^ch j`yakjhl bs stkrhn wbtcbl tch `bvhr iln

ousa`h tbssuh. ^ch erhidnkwl kf j`yakjhlkaaurs wchl ousa`hs lhhn hlhrjy iln wchltch `bvhr bs rhstkrblj i `kw e`kkn sujir `hvh`tk lkroi`.

Jùaklhkjhlhsbs.@iatith, ahrtibl ioblkiabns, iln j`yahrk` ail eh aklvhrthn bltkjùaksh. ^cbs prkahss, wcbac bs ai``hnjùaklhkjhlhsbs, tidhs pìah bl tch `bvhrwchl j`yakjhl supp`bhs irh ehblj nhp`hthniln wchl airekcynrith bltidh bs `kw.Jùaklhkjhlhsbs frko ìatith bs hsphabi``ybopkrtilt nurblj phrbkns kf cbjc ousa`hiatbvbty4 tch `bvhr aklvhrts hxahss ìatith

frko tch ousa`hs bltk jùaksh, wcbac bs tchlaya`hn eiad tk tch ousa`hs. ^cbs prkahss bsai``hn tch Akrb aya`h.

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Ckrokli` Akltrk` kf AirekcynrithOhtiek`bso^crhh ckroklhs hxhrtoimkr blthriatbvh hffhats upkl

airekcynrith ohtiek`bso= blsu`bl,jùaijkl, iln hpblhpcrblh. blsu`blprkokths tch uptidh iln utb`bzitbkl kfjùaksh ey tch ah``s. ^cus, blsu`bl`kwhrs tch e`kkn sujir `hvh`s.

Jùaijkl stbouìths tch aklvhrsbkl kfj`yakjhl tk jùaksh iln tcus ribshstch e`kkn jùaksh `hvh`s. Hpblhpcrblhbs rh`hishn bl rhspklsh tk iljhr, fhir,iln hxabthohlt. Bt i`sk stbouìths tchrh`hish kf jùaksh frko j`yakjhl ilnribshs e`kkn jùaksh `hvh`s.

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Fkroitbvh Isshssohlt

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Zcbac kf tch fk``kwbljaillkt eh ushn ey tch

j`yak`ysbs pitcwiy;j`uakshfruatkshrbekshily ail eh ushn

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rbeksh

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Hxahssbvh i`akck` aklsuoptbkl

wb`` rhsu`t bl tch fkroitbkl kf=j`yahri`nhcynhiahti`nhcynh`iatith

pyruvithAkI

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iahti`nhcynh

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Zcbac kf tch fk``kwblj bs LK^i akopklhlt kf tch h`hatrkl

trilspkrt acibl;akhlzyoh Yf`ivkprkthblbrkl-su`fur prkthblrbekskohaytkacrkoh A

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rbekskoh

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Zcbac kf tch fk``kwbljiats tk ribsh e`kkn sujir

`hvh`s;j`uaijklblsu`blthstksthrklh

aytkacrkoh A

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j`uaijkl

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Ektc j`uaijkl iln blsu`bl irhprknuahn ey tch pilarhis.

^ruhFi`sh

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^ch hln^cild yku fkr ykur itthltbkl

Furtchr Qtuny=Ebkachobstry iln Ah`` Ebk`kjyAk``hjh kf Qiblt Ehlhnbat iln Qiblt Mkcl's Xlbvhrsbty - Ebkachobstry Kl`blhBlnbili Xlbvhrsbty - Ohnbai` Ebkachobstry WijhOB^ - Ebk`kjy Cyphrthxtekkd

L@O - EbkachobstryL@O - Ok`hau`ir Ah`` Ebk`kjyXlbvhrsbty kf Xtic - LhtEbkacho
http://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.htmlhttp://themedicalbiochemistrypage.org/http://web.mit.edu/esgbio/www/http://www.ncbi.nlm.nih.gov/books/NBK21154/http://www.ncbi.nlm.nih.gov/books/NBK21475/http://library.med.utah.edu/NetBiochem/NetWelco.htmhttp://library.med.utah.edu/NetBiochem/NetWelco.htmhttp://library.med.utah.edu/NetBiochem/NetWelco.htmhttp://library.med.utah.edu/NetBiochem/NetWelco.htmhttp://library.med.utah.edu/NetBiochem/NetWelco.htmhttp://www.ncbi.nlm.nih.gov/books/NBK21475/http://www.ncbi.nlm.nih.gov/books/NBK21475/http://www.ncbi.nlm.nih.gov/books/NBK21475/http://www.ncbi.nlm.nih.gov/books/NBK21475/http://www.ncbi.nlm.nih.gov/books/NBK21154/http://www.ncbi.nlm.nih.gov/books/NBK21154/http://www.ncbi.nlm.nih.gov/books/NBK21154/http://www.ncbi.nlm.nih.gov/books/NBK21154/http://web.mit.edu/esgbio/www/http://web.mit.edu/esgbio/www/http://web.mit.edu/esgbio/www/http://web.mit.edu/esgbio/www/http://web.mit.edu/esgbio/www/http://themedicalbiochemistrypage.org/http://themedicalbiochemistrypage.org/http://themedicalbiochemistrypage.org/http://themedicalbiochemistrypage.org/http://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.htmlhttp://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.htmlhttp://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.htmlhttp://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/default.htmlhttp://www.imhotepvirtualmedsch.com/

ivms intro to biochemistry lecture 17 -carbohydrate metabolism

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