TUMORS

It’s a disturbance in growth:

Can be : 1- Acquired 2- Congenital

Neoplasia: it’s a new growth, purposeless

and progressive.

May be: Benign or Malignant .

1 -Adenoma in colon (Gross):

-Colonic adenomas are localized proliferations of dysplastic epithelium which are initially flat, but with increased growth project from the mucosa forming polyps. polyps have a head with a cobblestone or lobulated red-brown surface

2 -Adenoma in intestine (Micro):

Proliferated glands forming new acini variable in size and shape and lined by columnar cells .

3 -pericanalicular fibro adenoma in breast:

-Proliferative ducts ,rounded or oval . Their lumens are patent. They are lined by two layers of cells , outer flattened and inner cubical.-the ducts separated by fibrous tissue, the tumor is surrounded by fibrous capsule

4 -Fibroma:

Bundles of fibroblasts and collagen irregular arranged (or concentrically),fibroblasts are separated by pink bundles of collagen. the tumor is surrounded by fibrous capsule

5 -Fibromyoma:

-Red bundles of muscle tissue alternating with pink bundles of fibrous tissue.-muscle cell is spindle shaped with rod shaped nucleus ,the cell are seperated by pink collagen fibers, the tumour has no fibrous capsule.

6 -Neurilemmoma( Shwannoma):

-long thin spindle shaped cells with rod shape nuclei arranged in bundles.- The nuclei in each bundle are placed side by side in a palisade manner.- Tumour shows a fibrous capsule and few B.V

7 -Benign melanoma in skin:

-groups of nevus cells separated by collagen bundles, the nevus cells(melanocytes) are small, round or polyhedral, shows dark brown melanine pigment present in cells, the nevus has no capsule.