introduction_to_systemic_pathology.ppt

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    INTRODUCTIONTO SYSTEMIC

    PATHOLOGYUNIVERSITI KUALA LUMPUR

    MESTECH

    HLB 22104SYSTEMIC PATHOLOGY

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    INTRODUCTION

    Human perform homeostasis.

    If body cant correct the abnormalities in

    body???? Normal and abnormalities.

    Disease.

    Express disease.

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    TERMS

    Disease

    Pathology

    Etiology

    Idiopathic Sign

    Symptoms

    Homeostasis

    Prognosis and diagnosis

    Acute and chronic disease

    Remission and exacerbation

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    DIAGNOSIS

    Determination of nature of disease by:

    Sign and symptoms.

    Laboratory results.

    Laboratory tests:

    Urinalysis

    Blood chemistry

    Electrocardiography

    Radiography Diagnostic imaging technique

    Biopsy

    Surgical removal

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    Diversity of epidemiology

    Inflammation

    Autoimmune

    Allergy Infections

    Neoplasm

    Heredity Malnutrition

    Stress

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    Some athletes may develop

    abnormally high red blood cell

    counts. Why?In the athletes case, is this a

    sign of disease?

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    Pathogenesis of disease

    Disease are complex-molecular and cellular level.

    Interferon is a substances that stimulate immunesystem.

    Defences mechanisms of body system-inflammation.

    Autoimmunity- tolerance-fails-autoimmunedisease-autoantiboides.

    Eg of autoimmune disease:-rheumatic fever,glomerulonephritis, myasthenia gravis, andrheumatoid arthritis, SLE.

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    What is aging?

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    How aging occur?

    Life span of human.

    Factors contribute to aging: Environmental stress

    Cellular, genetic.

    Telomere clock

    Do you know about cell cycle?

    Contribution of telomere???

    Homeostasis imbalance & Development of disease

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    ISSUE ABOUT AGING???

    Bad or good.

    What are the effects???

    Concern-What happen to human body if wereach senescence.

    Age-related disease.

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    Too much theories in aging???

    How far we know about all the theories

    related to aging???

    Lets dig more