In the United States District Court

For The Eastern District of Virginia?!?IZ

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VERTEX PHARMACEUTICALS

INCORPORATED., a Delaware corporation,130 Waverly StreetCambridge, MA 02139

Plaintiff,

Civil Action No. /•' /o?6 <// B^3

HON. DAVID J. KAPPOS

Under Secretary of Commerce for IntellectualProperty and Director of the United StatesPatent and Trademark Office,Office of the General Counsel

United States Patent and Trademark OfficeP.O. Box 15667, Arlington, VA 22215Madison Building East, Room I0B20600 Dulany Street, Alexandria, VA 22314

Defendant.

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COMPLAINT

PlaintiffVertex Pharmaceuticals Incorporated ("Vertex" or"Plaintiff'), for its complaint

against the Honorable David J. Kappos (hereinafter "Kappos" or "Defendant"), states as follows:

NATURE OF THE ACTION

1. This is anaction by Vertex, the owner and assignee of United States Patent No.

8,188,281 (the '281 patent") for review ofthe determination by Defendant, pursuant to, inter alia, 35

U.S.C. § 154(b)(3)(B), ofthe Patent Term Adjustment ofthe '281 patent. Vertex seeks ajudgment

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