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MADRID. SPAIN, JUNE 6 th - 7 th 2013 AULA MAGNA. PABELLÓN DOCENTE. HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN. C/ IBIZA, 43. 28007 MADRID Symposium Director: Francisco Fernández Avilés PRELIMINARY AGENDA www.cardiovascularcelltherapy.com 10 th INTERNATIONAL SYMPOSIUM & ON STEM CELL THERAPY CARDIOVASCULAR INNOVATIONS

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MADRID. SPAIN, JUNE 6th - 7th 2013

AULA MAGNA. PABELLÓN DOCENTE. HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN.

C/ IBIZA, 43. 28007 MADRID

Symposium Director: Francisco Fernández – Avilés

PRELIMINARY AGENDA

www.cardiovascularcelltherapy.com

10 th INTERNATIONAL

SYMPOSIUM

& ON STEM CELL THERAPY

CARDIOVASCULAR

INNOVATIONS

2

3

www.cardiovascularcelltherapy.com

1

SCIENTIFIC AGENDA

2

ACCREDITATION

3

ORGANIZATION

4

EDUCATIONAL OBJECTIVES

5

FACULTY

6

GENERAL INFORMATION

7

WEBSITE

& 10 th INTERNATIONAL

SYMPOSIUM

www.cardiovascularcelltherapy.com

ON STEM CELL THERAPY

CARDIOVASCULAR

INNOVATIONS

4

5

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

7:45 - 8:30 REGISTRATION

8:30 - 9:00 WELCOMING

9:00 - 9:25 OPENING SPECIAL LECTURE

Chairs: Alberto San Román (Valladolid, Spain) Rafael Bañares (Madrid, Spain)

9:00 - 9:25 The Madrid stem cell cardiovascular meeting. Ten years after.

John Martin (London, UK)

9:30– 10:30 OPENING LECTURES

Chairs: Alberto San Román (Valladolid, Spain) Rafael Bañares (Madrid, Spain) 9:30 - 10:00 Pitfalls of cardiac stem cell therapy. The emergent role of tissue engineering and organ

manufacturing

Doris A. Taylor (Houston, USA)

10:00 - 10:30 Pursuing the definitive success of cardiac stem cell therapy: lessons from the last ten years

to move forward

Andreas Zeiher (Frankfurt, Germany)

10:30 - 12:10 WHAT’S NEW IN STEM CELL THERAPY FOR CARDIAC REPAIR? - I

Chairs: Stefan Janssens (Leuven, Belgium)

Bernardo Nadal-Ginard (Liverpool, UK)

Pannel Discussants: Felipe Prosper (Pamplona, Spain)

Roberto Fernández-Viña (Buenos Aires, Argentina)

Michael Schneider (London, UK)

Dominique Charron (París, France)

10:30 - 10:45 Cardiac stem cells. Are they the answer? Luis R. Borlado (Madrid, Spain)

10:45 - 11:00 Cardiovascular applications of IPs Juan C. Izpisúa (La Jolla, USA)

6

SCIENTIFIC AGENDA 1 THURSDAY, 6th June 2013

11:00 - 11:15 Human embryonic stem cell for postinfarction myocardial repair

Warren Sherman (New York, USA)

11:15 - 11:30 The use of human embryonic stem cells for heart repair: major translational issues Philippe Menasché (Paris, France)

11:30 - 11:45 How to make cells more efficient Atta Behfar (Rochester, USA) 11:45 - 12:10 Panel Discussion

12:10- 12:30 COFFEE BREAK

12:30 - 14:10 WHAT’S NEW IN STEM CELL THERAPY FOR CARDIAC REPAIR? - II

Chairs: Stefan Janssens (Leuven, Belgium)

Bernando Nadal-Ginard (Liverpool, UK)

Pannel Discussants: Felipe Prosper (Pamplona, Spain)

Roberto Fernández-Viña (Buenos Aires, Argentina)

Michael Schneider (London, UK)

Dominique Charron (París, France)

12:30 – 12:45 Pacemaker cells. Present and future Ira S. Cohen (New York, USA)

12:45 – 13:00 “In vivo” detection of stem cell viability

Philip C. Yang (Stanford, USA)

13:00 – 13:15 Chemokines and inflammation in heart disease. Adaptative or maladaptive Stephanie Dimmeler (Frankfurt, Germany)

13:15– 13:30 Tissues and organ decellullarization. Methods and criteria

Stephen S. Badylack (Pittsburg, USA)

13:30– 13:45 Stem cell delivery. Advantages of the retrograde approach

Jorge Tuma (Lima, Perú)

13:45 – 14:10 Panel Discussion

7

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

14:10- 15:00 Lunch and Poster Exhibition

Chairs and jury: Philippe Menasche (Paris, France)

Felipe Prosper (Pamplona, Spain)

In this “Poster Exhibition” research teams involved in the topic of the Symposium will have the opportunity of

presenting selected parts of their work to the audience.

The Poster Review Committee will select which the best posters of the session are. At the end of the session,

the verdict will be communicated. The winners of the Posters Awards will have to present their work (oral pres-

entation) the following day in the morning, in the session named “Best Poster Presentation”, when they will

receive their prize.

For more information regarding Poster Exhibition and Poster Awards, please contact us via e-mail at

[email protected]

15:00 - 17:00 LATE BREAKING CLINICAL TRIALS IN STEM CELL THERAPY

Chairs: Andreas Zeiher (Frankfurt, Germany)

Ricardo Sanz (Madrid, Spain)

Pannel Discussants: Emerson Perin (Houston, USA)

Juan Carlos Chachques (Paris, France)

Alberto San Román (Valladolid, Spain)

Antonio Piñeiro (Madrid, Spain)

15:00 – 15:15 Intracoronary infusion of BM-MNC early or late after AMI – 4 months: results of the SWISS-

AMI trial.

Daniel Sürder (Lugano, Switzerland)

15:15 – 15:30 Cardiospheres for postinfaction remodelling. Long term evaluation and perspectives.

Lessons from the CADUCEOUS

Eduardo Marbán (Los Angeles, USA)

15:30 – 15:45 Randomized comparison of allogenic vs autologous mesenchymal stem cells in patients with

ischemic cardiomyopathy (POSEIDON) Joshua Hare (Miami, USA)

15:45 – 16:00 Long-term improvement of LV function and infarct size after cardiac stem cell therapy:

5-year follow-up of the MYSTAR study Maryan Gyongyosi (Vienna, Austria)

16:00 – 16:15 Combined G-CSF and intramyocardial injection of bone marrow cells in heart failure

improves cardiac function and symptoms at 1-year.

Anthony Mathur (London, UK)

8

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

16:15– 16:30 Five-year results on intracoronary infusion of the mobilized peripheral blood stem cells by

granulocyte colony-stimulating factor in patients with myocardial infarction.

Hyo-Soo Kim (Seoul, South Korea)

16:30-17:00 Panel Discussion

17:10 - 18:10 DISCOVERIES AND INVENTIONS

Chairs: John Martin (London, UK)

Juan Carlos Chachques (Paris, France)

Pannel Discussants: Nabil Dib (San Diego, USA)

André Terzic (Rochester, USA)

Andreu Climent (Madrid, Spain)

Doris Taylor (Houston, USA)

17:10 - 17:25 Stem cell based organ engineering. The role of bioareactors Joseph Consiglio (Boston, USA)

17:25- 17:40 Gadonanotubes as magnetic nanolabels for stem cell retention Emerson Perin (Houston, USA)

17:40-17:55 Transplantation of an allogeneic vein bioengineered with autologous stem cells: a proof-of-

concept study Suchitra Sumitran-Holgersson (Gothenburg, Sweden)

17:55– 18:10 Fiberoptic cardioscopy for stem cell delivery.

Eric H. Duckers (Rotterdam, The Netherlands)

18:10– 18:25 Making bioartificial grafts perfusable

Milica Radisic (Toronto, Canada)

18:30– 20:00 EDUCATIONAL WORKSHOPS

18:30 - 20:00 Workshop on practical stem cell biology made simple. Chairs Mª Eugenia Fdez-Santos (Madrid, Spain) Philippe Menasché (Paris, France) 18:30 - 20:00 Workshop on Tissue engineering Chairs Pedro L. Sánchez (Madrid, Spain) Doris A. Taylor (Houston, USA) 18:30 - 20:00 Workshop on clinical trials. A new era for cardiovascular repair: clinical trials to come Chairs Jozef Bartunek (Aalst, Belgium) Alberto San Román (Valladolid, Spain) 18:30 - 20:00 Workshop on new methods of stem cell delivery Chairs Emerson Perin (Houston, USA) Ricardo Sanz-Ruiz (Madrid, Spain)

9

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

EDUCATIONAL WORKSHOP 1 (ROOM 1)

Practical Stem Cell Biology Made Simple

Chairs Mª Eugenia Fdez-Santos (Madrid, Spain)

Philippe Menasché (Paris, France)

Local coordinator:

Workshop objectives

To learn basic methodology for the isolation, identification and characteriza-

tion of different types of stem cells applied in cardiovascular diseases.

Simple presentation of techniques for cellular tracking in vitro e in vivo.

To learn how to do histological studies in cardiac tissue: paraffin sections, cry-

osections, staining of paraffin embedded sections and cryosections, etc..

To learn and interpret basic electrophysiology in cardiac tissue.

(18:30 - 18:40) Cells: types, identification, methods of isolation Atta Behfar (Rochester, USA) (18:40 - 18:50) Cells tracking: in vitro and in vivo cellular tracking Felipe Prosper (Pamplona, Spain) (18:50 - 19:00) Histology: staining, antibodies, microscopy Emilio Alvarez (Madrid, Spain) (19:00 - 19:10) Electrophysiology in cardiac tissue. Techniques in vivo and in

vitro Andreu M. Climent (Madrid, Spain) (19:10 - 19:40) Discussion

10

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

EDUCATIONAL WORKSHOP 2 (ROOM 2)

Tissue Engineering

Chairs Pedro L. Sánchez (Madrid, Spain)

Doris A. Taylor (Houston, USA)

Local coordinator:

Workshop objectives

To bring together basic, preclinical and clinical, scientific and biotechnol-ogy companies to help build better connections between these communi-ties. To understand the principles and concepts of cardiovascular tissue engi-neering assessing the State-of-the-Art on the use of stem cells, synthetic and biological matrices and bioreactors. To demonstrate practical applications of cardiac tissue engineering To learn the principles and concepts of animal models to explore cardiac tissue engineering xenotransplantation To learn immunogenicity motorization techniques and methods. To understand the commercial and exploitation steps to develop a tissue engineering product

(18:30 - 18:40) Techniques and results of decellularization-based cardiovascular tissue-engineering. Gino Gerosa (Padova, Italy) (18:40 - 18:50) Biomaterial SpiberTM for patients with heart failure and coronary artery diseases My Hedhammar (Uppsala, Sweden) (18:50 - 19:00) Tissue engineering with the aid of inkjet printers Jose Manuel Torralba (Madrid, Spain)

(19:00 - 19:10) Electroestimulation in the development of bioartificial myocardium Juan Carlos Chachques (Paris, France) (19:10 - 19:20) The Mayo Program in Biologic Valve Develpment Robert D. Simari (Rochester, USA) (19:20 - 19:50) Discussion

11

THURSDAY, 6th June 2013 SCIENTIFIC AGENDA 1

EDUCATIONAL WORKSHOP 3 (ROOM 3)

Clinical Trials. A new era for cardiovascular repair: clinical trials to

come

Chairs Jozef Bartunek (Aalst, Belgium)

Alberto San Román (Valladolid, Spain)

Local coordinator:

Workshop objectives

To learn how definitive phase III clinical trials in stem cell therapy have been designed (sample size, arms of intervention, follow-up, etc…). To discuss the regulatory and organization issues needed to conduct such large trials. To reflect on clinical endpoints that should be addressed in phase III clinical trials in the field of stem cell therapy. To learn how to standardize cell isolation and cell delivery procedures in the case of multicentre trials.

(18:30 - 18:40) Stem cell therapy after acute myocardial infarction. The BAMI trial. Anthony Mathur (London, UK) (18:40 - 18:50) Stem cell therapy for chronic ischemic cardiomyopathy with ischemia. The RENEW trial. Andrea Hunt (Deerfield, USA) (18:50 - 19:00) Stem cell therapy for chronic ischemic cardiomyopathy with out ischemia. The CHART-1 trial. Jozef Bartunek (Aalst, Belgium) (19:00 - 19:10) Autologous mesenchymal stem cells for chronic myocardial ischemia and decreased left ventricular ejection fraction. The MESAMI trial Jerome Roncalli (Toulouse, France)

(19:10 - 19:20) Repetitive autologous MSC in ejections in IHD patients. The RIPASSA study. Steven A.J. Chamuleau (Utrecht, The Netherlands) (19:20 - 19:50) Discussion

12

SCIENTIFIC AGENDA 1

EDUCATIONAL WORKSHOP 4 (ROOM 4)

Workshop on new methods of stem cell delivery Chairs Emerson Perin (Houston, USA)

Ricardo Sanz-Ruiz (Madrid, Spain) Local coordinator:

Workshop objectives

To learn about old and new technologies for stem cell delivery to the heart. To discuss the importance of cell retention rates, safety and feasibility, and technical characteristics of every route. To reflect on the most appropriate technique in every specific clinical subset of cardiovascular disease. To learn how to standardize cell delivery procedures in the case of multicentre trials.

(18:30 - 18:40) Intracoronary delivery in other scenarios apart from acute myocardial infarction. Rationale and methods.

José Suárez de Lezo (Cordoba, Spain)

(18:40 - 18:50) Intracoronary delivery. New technologies (the Dib-cath). Nabil Dib (San Diego, USA)

(18:50 - 19:00) Transendocardial route with 3D-guidance: the NOGA XP system (Biologics Delivery Systems).

Pilar Jiménez-Quevedo (Madrid, Spain)

(19:00 - 19:10) Transendocardial delivery with the Helix catheter (Biocardia).

Peter Altman (San Carlos, USA)

(19:10 - 19:20) Transendocardial delivery with the C-Cath catheter (Cardio3- Sciences).

Ricardo Sanz-Ruiz (Madrid, Spain)

(19:20 - 19:50) Discussion

THURSDAY, 6th June 2013

13

FRIDAY, 7th June 2013

9:00 - 9:40 BEST POSTER PRESENTATION

Chairs: Philippe Menasché (Paris, France)

Felipe Prosper (Pamplona, Spain)

9:00 - 9:10 Prizes-giving

9:10 - 9:25 Winner work presentation and discussion

9:25 - 9:40 Winner work presentation and discussion

9:50 - 11:10 RECENT CONTRIBUTIONS PRESENTED BY YOUNG

INVESTIGATORS

Chairs: Philippe Menasché (Paris, France)

Felipe Prosper (Pamplona, Spain)

Pannel Discussants: Javier Bermejo (Madrid, Spain)

Doris Taylor (Houston, USA)

Eduardo Marbán (Los Angeles, USA)

Warren Sherman (New York, USA)

9:50 – 10:05 Intracoronary injection of microsphere-encapsulated antagomir 92a to prevent post-

infarction remodeling

Neus Bellera (Barcelona, Spain. David García-Dorado’s group)

10:05 – 10:20 Very small embryonic-like cells (VSEL) – a novel population of cardiac stem cells

Tomasz Jadczyk (Katowice, Poland. Michal Tendera’s group)

10:20 – 10:35 Allogenicity of human cardiac stem/progenitor cells orchestrated by programmed death

ligand 1

Laura Lauden (Paris, France. Dominque Charron’s group)

10:35 – 10:55 Traceless reprogramming for proficient cardiogenicity of iPS cells

Almudena Martinez (Rochester, USA. André Terzic’s group)

10:55 - 11:15 Panel Discussion

11:15 - 11:45 COFFEE BREAK

SCIENTIFIC AGENDA 1

14

SCIENTIFIC AGENDA 1

11:45– 13:20 HOT TOPICS OF THE YEAR

Chairs: Miguel Torres (Madrid, Spain)

Arturo Fernández-Cruz (Madrid, Spain)

Pannel Discussants: Dominique Charron (Paris, France)

Philippe Menasché (Paris, France)

David García-Dorado (Barcelona, Spain)

Atta Behfar (Rochester, USA)

11:45 - 12:05 NON CARDIOVASCULAR TOPIC OF THE YEAR Stem Cells and Spinal Cord Repair Evan Y. Snyder (La Jolla, USA)

12:05 – 12:25 BASIC CARDIOVASCULAR TOPIC OF THE YEAR Snake-derived drugs for cardiac growth. Not just venom-makers Leslie Leinwand (Tuscaloosa, USA)

12:25 – 12:45 TRANSLATIONAL CARDIOVASCULAR TOPIC OF THE YEAR Stem cell based transcatheter aortic valve implantation Simon P. Hoerstrop (Zurich, Switzerland)

12:45 – 13:05 CLINICAL CARDIOVASCULAR TOPIC OF THE YEAR Scientific analysis of the cardiac impact of bone marrow cells in clinical trials Buddhadeb Dawn (Kansas, USA)

13:05 – 13:25 Discussion

13:25 - 14:25 CLOSING SESSION

Chairs: Rafael Matesanz (Madrid, Spain) 13:25 – 13:45 Cells for cardiac repair. Milestones and unmet needs Eduardo Marban (Los Angeles, USA)

13:45– 14:05 Cardiovascular stem cell therapy. What is the clinical evidence? Roberto Simari (Rochester, USA)

14:05– 14:25 Cardiovascular stem cell therapy. Looking forward. Valentin Fuster (New York, USA)

14:25 - 14:40 ADJOURN

Francisco Fernández-Avilés (Madrid, Spain)

FRIDAY, 7th June 2013

15

FRIDAY, 7th June 2013 SCIENTIFIC AGENDA 1

16

ACCREDITATION 2

ORGANIZATION 3

· Spanish Society of Cardiology.

Continuing Medical Education Accreditation Program. Activity accredited

by the Spanish Society of Cardiology for 8.5 credit hours

· EBAC (European Board for Accreditation in Cardiology).

Activity accredited by the European Board for Accreditation in Cardiology

for 9.0 credit hours.

· Comisión de Formación Continuada. Sistema Nacional de Salud. Activity

accredited for 2.0 credit hours.

DIRECTION Francisco Fernández-Avilés Servicio de Cardiología Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Hospital General Universitario Gregorio Marañón (Madrid, Spain) CO-DIRECTION Mª Eugenia Fernández Santos Instituto de Investigación Sanitaria Gregorio Marañón Hospital General Universitario Gregorio Marañón (Madrid, Spain) Bernard Gersh Mayo Clinic (Rochester, USA) John F. Martin Centre for Cardiovascular Biology & Medicine (London, United Kingdom) José Alberto San Román Hospital Clínico-Universitario de Valladolid (Valladolid, Spain) Pedro L. Sánchez Instituto de Investigación Sanitaria Gregorio Marañón Hospital General Universitario Gregorio Marañón (Madrid, Spain) Ricardo Sanz Ruiz Instituto de Investigación Sanitaria Gregorio Marañón Hospital General Universitario Gregorio Marañón (Madrid, Spain) Doris A. Taylor Texas Heart Institute (Houston, USA) Andras W. Zeiher University of Frankfurt (Germany)

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TECHNICAL DIRECTION

Ana Fernández Baza Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Servicio de Cardiología Hospital General Universitario Gregorio Marañón

INTERNATIONAL SCIENTIFIC ADVISORY BOARD

EXECUTIVE LOCAL COMMITTEE Carmen G. Morante Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) - Hospital G. Universitario Gregorio Marañon, Madrid Enrique Gutierrez Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) - Hospital G. Universitario Gregorio Marañon, Madrid Adolfo Villa Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) - Hospital G. Universitario Gregorio Marañon, Madrid

ORGANIZATION

Instituto de Investigación Sanitaria Hospital Gregorio Marañón.

Servicio de Cardiología. Hospital General Universitario Gregorio Marañón, Madrid.

Red Temática de Investigación Cardiovascular del Instituto de Salud Carlos III (RECAVA)

Red Temática de Terapia Celular del Instituto de Salud Carlos III (TERCEL)

Grupo de Terapia Celular Aplicada al Miocardio (TECAM, Hospital General Universitario Gregorio Ma-rañón -Madrid-, Hospital Clínico-Universitario de Valladolid, Hospital Río Hortega - Valladolid-, Instituto de Biología y Genética Molecular - Universidad de Valladolid-)

Task Force on Stem Cell Regeneration of the Heart (European Society of Cardiology)

ORGANIZATION 3

Jozef Bartunek (Aalst, Belgium) John Martin (London, United Kigdom)

Nabil Dib (San Diego, USA) Philippe Menasche (Paris, France)

Stefanie Dimmeler (Frankfurt, Germany) Bernardo Nadal-Ginard (Liverpool, UK)

Valentín Fuster (New York, USA) Emerson Perin (Houston, USA)

Bernard Gersh (Rochester, USA) Doris Taylor (Houston,USA)

Juan Carlos Izpisúa (La Jolla, USA) William Wijns (Aalst, Belgium)

Stefan Janssens (Leuven, Belgium) Andreas Zeiher (Frankfurt, Germany)

Anthony Mathur (London, United Kingdom)

18

EDUCATIONAL OBJECTIVES 4

This symposium is aimed at both medical and non-medical scientists interested in the study and appli-cation of stem cell therapy and other biotechnological advances for the prevention and treatment of cardiovascular failure. For this reason the audience comprises:

a. Preclinical researchers from all areas wishing to deepen their knowledge of cardiovascular bio-technological developments with therapeutic potential.

b. Doctors specialising in the care of patients suffering from cardiovascular diseases, and who are interested in finding out about and discussing the current state of affairs and the future pros-pects for the application of these new therapeutic methods.

c. Doctors involved in interventions dedicated to cardiovascular pathology and who are inter-ested in the results and perspectives of gene vehiculization techniques, the stimulation of en-dogenous progenitors, cell transplant or electromechanical helps to fight cardiovascular dis-ease.

d. Medical or no medical professionals interested in the development of units and networks aimed at the translation of cardiovascular knowledge from bench to bedside and vice versa.

e. Medical or no medical professionals interested in envisaging the opportunities for competition of biotechnology in the cardiovascular field

At the end of the conference those present will have acquired the following skills:

1. Knowledge and ability to discuss the latest advances in the role of progenitor cells in the integ-rity of the cardiovascular system of a healthy individual.

2. Knowledge and ability to discuss the latest experimental advances in the renewal and repair capacity of the damaged cardiovascular structure via the transplant of adult or embryonic stem cells or the stimulation of endogenous progenitors,.

3. Know about and be able to objectively debate the current state of feasibility, safety and effi-cacy with regards to the clinical application of cell therapy and other new biotechnological treatments.

4. Knowledge and ability to debate objectively on the efficiency of these types of treatment in patients with acute or chronic cardiovascular diseases.

5. Ability to predict the possibilities of scientific and professional attitude with regards to offering these therapeutic methods.

6. Ability to evaluate and decide one’s own ability to participate in the application of these thera-pies for healthcare, clinical, and preclinical purposes.

7. Ability to identify those institutions and groups with the highest performance capabilities in these fields, and be able to establish contacts for educational, scientific, and healthcare pur-poses.

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FACULTY 5

Peter Altman (Madrid, Spain)

Emilio Alvarez (Madrid, Spain)

Stephen S. Badylack (Pittsburg, USA)

Rafel Bañares (Madrid, Spain)

Jozef Bartunek (Aalst, Belgium)

Atta Behfar (Rochester, USA)

Neus Bellera (Barcelona, Spain)

Javier Bermejo (Madrid, Spain)

Luis R. Borlado (Madrid, Spain)

Juan Carlos Chachques (Paris, France)

Steven A. J. Chamuleau (Utrech, The Netherlands)

Dominique Charron (Paris, France)

Andreu M. Climent (Madrid, Spain)

Ira S. Cohen (New York, USA)

Joseph Consiglio (Boston, USA)

Buddhadeb Dawn (Kansas, USA)

Nabil Dib (San Diego, USA)

Stephanie Dimmeler (Frankfurt, Germany)

E. H. Duckers (Rotterdam, The Netherlands)

Francisco Fernández-Avilés (Madrid, Spain)

Arturo Fernández-Cruz (Madrid, Spain)

Mª Eugenia Fdez-Santos (Madrid, Spain)

Roberto Fernández-Viña (Buenos Aires, Argentina)

Valentin Fuster (New York, USA)

David García-Dorado (Barcelona, Spain)

Gino Gerosa (Padova, Italy)

Maryan Gyongyosi (Vienna, Austria)

Joshua Hare (Miami, USA)

My Hedhammar (Uppsala, Sweden)

Simon P. Hoerstrop (Zurich, Switzerland)

Andrea Hunt (Deerfield, USA)

Juan C. Izpisúa (La Jolla, USA)

Tomasz Jadczyk (Katowice, Poland)

Pilar Jiménez-Quevedo (Madrid, Spain)

Hyo-Soo Kim (Seoul, South Korea)

Laura Lauden (Paris, France)

Leslie Leinwand (Tuscaloosa, USA)

Eduardo Marban (Los Angeles, USA)

John Martin (London, UK)

Almudena Martínez (Rochester, USA)

Anthony Mathur (London, UK)

Philippe Menasché (Paris, France)

Bernardo Nadal-Ginard (Liverpool, UK)

Emerson Perin (Houston, USA)

Antonio Piñeiro (Madrid, Spain)

Felipe Prosper (Pamplona, Spain)

Milica Radisic (Toronto, Canadá)

Jerome Roncali (Touluse, France)

Alberto San Román (Valladolid, Spain)

Ricardo Sanz (Madrid, Spain)

Michael Schneider (London, UK)

Warren Sherman (New York, USA)

José Suárez de Lezo (Cordoba, Spain)

Robert D. Simari (Rochester, USA)

Evan Y. Snyder (La Jolla, USA)

Suchitra Sumitran -Holgersson (Gothenburg, Sweden)

Daniel Sürder (Lugano, Switzerland)

Doris A. Taylor (Houston, USA)

Andre Terzic (Rochester, USA)

José Manuel Torralba (Madrid, Spain)

Miguel Torres (Madrid, Spain)

Jorge Tuma (Lima, Perú)

Kai C. Wollert (Hannover,Germany)

Philip C. Yang (Stanford, USA)

Andreas Zeiher (Frankfurt, Germany)

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GENERAL INFORMATION 6

MEETING VENUE

Aula Magna. Pabellón Docente. Hospital General Universitario Gregorio Marañón.

C/ Ibiza, 43. 28007 Madrid, Spain

DATE

June 6th and 7th , 2013

OFFICIAL LANGUAGES

English and Spanish (simultaneous translation will be available)

TECHNICAL SECRETARIAT

Viajes Orbiazul

C/ Alonso Pesquera, 2

47002 Valladolid

Tf. 00 34 983 30 91 92

Fx. 00 34 983 29 53 51

[email protected]

[email protected]

RETIRO

21

WEBSITE 7

The website www.cardiovascularcelltherapy.com is a virtual place which contains all the information related to this Symposium and its previous editions

It is possible through this web-site to access the scientific program, to register and to reserve accom-modation.

It is also a priority for this web site to offer updated information about Stem Cell Therapy for Cardio-vascular Diseases, so appropriate access to related sites has been created.

You can also join us on Facebook and Twitter.

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TECHNICAL DIRECTION

Ana Fernández Baza

Hospital General Universitario Gregorio Marañón

C/ Doctor Esquerdo, 46. 28007 Madrid

T. 00 34 91 426 58 82 / F. 00 34 91 586 82 76

[email protected]

TECHNICAL SECRETARIAT

Viajes Orbiazul

C/ Alonso Pesquera 2. 47002 Valladolid

T. 00 34 983 30 91 22 / F. 00 34 983 29 53 51

[email protected]

DIRECTION

Francisco Fernández-Avilés

Instituto de Investigación Sanitaria Gregorio Marañón

Hospital General Universitario Gregorio Marañón (Madrid, Spain)

CO-DIRECTION

Mª Eugenia Fernández Santos

Instituto de Investigación Sanitaria Gregorio Marañón

Hospital General Universitario Gregorio Marañón (Madrid, Spain)

Bernard Gersh

Mayo Clinic (Rochester, USA)

John F. Martin

Centre for Cardiovascular Biology & Medicine (London, United Kingdom)

José Alberto San Román

Hospital Clínico-Universitario de Valladolid (Valladolid, Spain)

Pedro L. Sánchez

Instituto de Investigación Sanitaria Gregorio Marañón

Hospital General Universitario Gregorio Marañón (Madrid, Spain)

Ricardo Sanz Ruiz

Instituto de Investigación Sanitaria Gregorio Marañón

Hospital General Universitario Gregorio Marañón (Madrid, Spain)

Doris A. Taylor

Texas Heart Institute

(Houston, USA)

Andras W. Zeiher

University of Frankfurt (Germany)

ACCREDITATION