integrated ncm medicine with s-ncm new knowledge 2nd edition.pdf

M.Ambaga, A.Tumen-Ulzii

Integrated NCM medicine with s-NCM new knowledge (Second edition)

E-mail : [email protected]

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CONTENTS

1 FIRST PART

General principles 4

2 How it is connected the formation of universe with formation of protons

and electrons 6

3 What role is played a protons and electrons in the normal functioning

of living cells 7

4 Almost all previously unsolved questions completely explained and

fully clarified. 11

5 What is coincidence between abstract theory of Rlung, Mkhris, Badgan

and the membrane - redoxy potentials three state line systems existed

between a donators and acceptors of living cells that have been

revealed by us 13

6 s-NCM knowledge may be described in following orders 21

7 The definition of NCM medicine 22

8 What is the new knowledge about basic 4 compartments of human

body 28

9 What is the new knowledge about 10 basic functional systems of

human body 29

10 SECOND PART

Historical and practical aspects of NCM medicine 30

11 The pulsediagnostic method of oriental medicine and membrane

redoxy potentials 3 state line system of 14 trillion cells 95

12 THIRTH PART

Education aspects of NCM medicine 120

13

Basic methods of investigation, conducted by us to creating of

experimental models of cell regulation, coded by abstract rlung, mkhris,

badgan thermins in Traditional medicine 142

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The serious mistake revealed by Mongolian researcher professor

Ambaga in one widely in the world used biochemical equation 148




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Socrates: There is only one good: knowledge and the only evil: ignorance.

Key words: "rlung, Mkhris, Badgan – membrane - redoxy potentials 3 state line

system existed in 14 trillion cells.

1. General principles:

a. The life was became strongly dependent from the presence of protons and

electrons, which were formed during a events called as big bang, 15 billion years

ago.i.e.the protons and electrons, which were formed during a events called as big

bang through the process termed as singularity 15 billion years ago sets the stage for

the formation of life in the universe.

b. Diagnosis and treatment, including a Traditional and Modern medicine should be

based on the morpho - functional unit, which really are existed inside a human body,

which we can see and measure.

2. Questions and answers:

a. How the life become dependent from protons and electrons, formed during a

events called as big bang, 15 billion years ago through the process termed as

singularity.

b. What are existed inside a human body. (Inside a human body are existed protons

and electrons, proton - electron dependent systems, also proton - electron delivery

systems, proton - electron utilizing systems).

c. Inside a human body are not existed living vata, kapha, pitta, rlung, mkhris,

badgan, which we can not see and measure.

In such way it is categorically resisted, refused the opinions, relating to coexistence

of ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata, kapha,

pitta‖, ―Homo sapiens plus yan, yin‖ human species (human species, containing a

living rlung, mkhris, badgan, yin, yan are not registered in Linnaean taxonomy) along

with ―Homo sapiens‖ human specie.

What is ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata, kapha,

pitta‖, ―Homo sapiens plus yan, yin‖ human specie, it is really not existed human

specie, as if containing the 14 trillion living rlung, mkhris, badgan, yin, yan along with

14 trillion living cells only postulated by Traditional medicine, all their diagnostic and

treatment methods based in this form of human specie, but categorically resisted,

refused by NCM medicine.




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The notion about living things existed inside human body had been changed from

time to time during last 3000 years. At first appeared the imanigation in Traditional

medicine 3000 years ago as if inside of human body exist a living functioned rlung,

mkhris, badgan, yin, yan, vata, kappa, pitta, these thinkings were acceptable until this

period when 1665 year Robert Hooke discover a living cells. After Robert Hooke

discovery of living cells the old imanigation relating to a living functioned rlung,

mkhris, badgan, yin, yan, vata, kappa, pitta existing inside of human body had

completely lost own theoretical and practical significances. Traditional medicine

3000 years ago as if inside of human body exist a living functioned rlung, mkhris,

badgan, yin, yan, vata, kappa, pitta, these thinkings were acceptable until this period

when 1665 year Robert Hooke discover a living cells. But the intellectual shift

process of substitution of old imanigation about existence of a living functioned

rlung, mkhris, badgan, yin, yan, vata, kappa, pitta by the new cell theory discovery as

existence of only one living cells inside of human body had not made yet by

scientists, working in both medicine. Such missing of intellectual shift substitution of

old knowledge of Traditional medicine by new cell theory knowledge and serious

mistakes about existence of a living functioned rlung, mkhris, badgan, yin, yan,

vata, kappa, pitta inside of human body lead to spread the antiscientific thought

about the paralleled coexistence of both living things inside human body in one side

a living functioned rlung, mkhris, badgan, yin, yan, vata, kappa, pitta, in other side

living cells together followed by false recognisation as if existed a ―Homo sapiens

plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens

plus yan, yin‖ human species. Old thinking of Traditional medicine about that a

human body consisted of living functioned rlung, mkhris, badgan, yin, yan, vata,

kappa, pitta should be replaced by cell theory of Human body. The first person to

describe a cell was Robert Hooke. His popular book Microphagia: or Some

Physiological Descriptions of Miniature Bodies Made by Magnifying Glasses,

produced in 1665. It revealed to an enchanted public a universe of the very small that

was far more diverse, crowded, and finely structured than anyone had ever come

close to imagining. Among the microscopic features first identified by Hooke were

little chambers in plants that he called ―cells‖ because they reminded him of monks’

cells. Hooke calculated that a one - inch square of cork would contain 1,259,712,000

of these tiny chambers - the first appearance of such a very large number anywhere

in science. Microscopes by this time had been around for a generation or so, but

what set Hooke’s apart were their technical supremacy. They achieved

magnifications of thirty times, making them the last word in seventeenth - century

optical technology (Bill Bryson, Short history of nearly everything).

c. How it is connected the formation of universe with formation of protons and

electrons.

d. What is s - NCM knowledge and NCM medicine.




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e. What is link between a Dala Lama teachings relating to Integrated medical

systems, consisted of Traditional and Modern medicine.

i. From what is the human body made

“Tibetian medicine is far more advanced in the understanding of nature of mind than

Western medicine. In matters of understanding the physical functions of the human

body, the Tibetian medicine …is less advanced than Western medicine. Without

mixing the two approaches, and without saying one is better than the other, both

schools should work together in order to find ways of understanding each other and

thus boost the effectiveness of the two healing techniques”. H.H.Dalai Lama.

FIRST PART

HOW IT IS CONNECTED THE FORMATION OF UNIVERSE WITH FORMATION

OF PROTONS AND ELECTRONS

And so, from nothing, our universe begins.

Big bang - 10 - 43 seconds - universe is 10 - 28 cm in diameter - beginning of gravity,

10 - 35 seconds - universe is size of baseball, first particles - quarks and electrons,

10-6 seconds - universe is size of present solar system, quarks form protons and

neutrons. 3 minutes protons and neutrons form nuclei, electrons still free, 100 000

years after Big Bang electrons joins nuclei to form atoms, radiation separates from

matter - first light, 100 000 years after Big Bang matter begins to concentrate,

universe transparent to light, 6,6 bya Universe one - quarter present size, 5,0 bya

solar system forms, Universe two -thirds - present size, 4,5 0 bya earth formed, 4, 0

bya first life in earth.

In a single blinding pulse, a moment of glory much too swift and expansive for any

form of words, the singularity assumes heavenly dimensions, space beyond

conception. In the first lively second (a second that many cosmologists will devote

careers to shaving into ever-finer wafers) is produced gravity and the other forces

that govern physics. In less than a minute the universe is a million billion miles across

and growing fast. There is a lot of heat now, ten billion degrees of it, enough to begin

the nuclear reactions that create the lighter elements - principally hydrogen and

helium, with a dash (about one atom in a hundred million) of lithium. In three minutes,

98 percent of all the matter there is or will ever be has been produced. We have a

universe. It is a place of the most wondrous and gratifying possibility, and beautiful,

too. And it was all done in about the time it takes to make a sandwich (Short history

of nearly everything, p.11).

Michel Alan Park, Biological anthropology (p.116)

The universe began at single location and evidence indicates that it started as

incredibly tiny, dense, and hot speck (the proper term is singularity) composed of




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pure energy that would one day become all the energy and space and matter -

including us of universe we know. At the beginning of time - we shall use 15 bya -

this speck began to expand and event called the big bang, although it was not really

an explosion. It more like a ballon being rapidly inflated - ballon that contained both

energy and space. It is hypothesized thati this inflation was caused by the

accumulation of material that produced a repulsative force - the opposite of gravitys

attracting force.

For our purpose here, suffice it to say that as the newborn universe expanded (15

billion - bya years ago), it cooled, a matter quickly condensed from energy. Within 3

minutes after the beginning, protons and neutrons had formed and joined to make

atomic nuclei, but it took another 100 000 years for electrons to join the nuclei to form

atoms. At about the same time, radiation separated from matter and there was light,

but the next 200 000 years the universe was still too dense for that light travel

through it. By 12 bya, galaxies had begun to form as gravity pulled matter together in

to huge clusters. These made up of stars that mainly hydrogen, the simplest element.

As a result of the nuclear reaction in these stars, heaver, more complex element

formed. When these old stars died in tremendous supernova explosions, their

elements were scattered in to space, some eventually contributing to the formation of

new galaxies with all stars with all their stars and, in several known cases, planet.

Amazingly, in less than a billion years may be 3,6 bya - life on earth was established.

WHAT ROLE IS PLAYED A PROTONS AND ELECTRONS IN THE

NORMAL FUNCTIONING OF LIVING CELLS

During 3,8 billion years lasted formation of the life process in the universe have

been created the lawfull process of dependence of any form of life from protons and

electrons, which had formed and joined to make atomic nuclei 15 billion - bya yeara

ago.

But the globally used equation of living cell metabolic reaction did not reflect this

events, which appeared with participation of protons and electrons.

In such way, recently, a new knowledge based explanation on the globally used

equation of metabolic reaction is required.

Donators (glucose - source of protons and electrons) + O2 (acceptor of protons) =

Energy (ATP + heat energy) + H2O + CO2 is the globally used equation of metabolic

reaction.

But here we could not see the such morpho - functional unit, through which have

been conducted a normal flow of protons and electrons from donators to electrons

with generation of high phosphate compound as ATP.

The left hand side of the equation is an acceptor of protons and electrons or oxygen

(O2) which gets through respiration and C6 H12O6, carbohydrate, aminoacids, fatty

acids or donator of protons and electrons that gets into the body in a form of food.




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Meanwhile the right hand side of the equation shows ―energy - ATP, water molecule

and carbon dioxide which are formed inside the human body because of a normal

flow of protons and electrons.

The left hand side of the equation has two members while the right hand side has

three members as if the balance has been shifted heavily to the right side and the left

side is being light-weighted or missing something.

It’s curious, why the human body or living cell representation participation is omitted

in the left hand side of this equation.

The world is expecting of meaningfull explanation of the above equation which is

missing a very important element.

Logically, therefore there would be ―main regulatory system with many stations of

reaction on the left hand side of the equation, through which constantly conducted

the normal flow of flow of protons and electrons with formation of ATP and thermal

energy.

More clearly, that regulatory system would facilitate explaining the:

Reaction medium between C6H12O6 + 6O2 = energy + 6H2O + 6CO2

Three distinct variations of ATP;

Three distinct variations of heat energy.

Three distinct variations of water molecules

Three distinct variations of water molecules

Three distinct variations of CO2 molecules in right hand of reaction.

The world has an inadequate definition/explanation/ about the formula of equation

that is being used in measuring of the metabolic reaction kinetics as flow of protons

and electrons, formed during a events called as big bang, 15 billion years ago

through the process termed as singuiarity between donators and acceptor and

energy generation.

It is known that an adequate amount of energy (ATP + heat) is not being created on

the right side of the equation even if carbohydrate, aminoacids, fatty acids are of




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adequately high amount on the left side of the equation with direct participation of a

donators of electrons, protons, formed during a events called as big bang, 15 billion

years ago through the process termed as singularity.

Why is that? There is no answer yet.

It’s known that under certain conditions, an adequate amount of energy (ATP + heat

energy) is created on the right hand side with using a donators of electrons, protons,

formed during a events called as big bang, 15 billion years ago through the process

termed as singuiarity even if there is not adequately high amount of carbohydrate,

aminoacids, fatty acids as donators of electrons, protons on the left hand side of the

equation. Why do such conditions form? There is no answer yet.

Why was the idea of three state formed instead of one state on three state line of

membrane - redoxy potential?

Under certain conditions, it is changed ―ATP: heat energy‖ ratio with direct

participation of a donators of electrons, protons, formed during a events called as big

bang, 15 billion years ago through the process termed as singuiarity :

- as ATP medium level + high heat energy = 100%- in case of autumn,

middle of the day, high amount of unsaturated fatty acid is used and thyroxin,

adrenaline content is increased.

- as ATP high level + low heat energy = 100% - in case of spring, middle of the

night, high amount of saturated fatty acid is used and thyroxin, adrenaline content is

lowered.




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- as ATP low level + low heat energy = less than 100% in case of the old age,

low amount of saturated, unsaturated fatty acid is used.

Based on all of these, it can be concluded that the functional system which is situated

between the donator and acceptor on the left hand side exists in 3 states.

However, it’s not written in any book that above 3 state changes are being initiated

due to ―which structure unit of function‖.

Theoretically, it was first known that ―oxidation: phosphorylation‖ ratio changes into 3

different states inside the equation environment.

It became clear that ―oxidation: phosphorylation‖ ratio is changing into 3 different

states inside the equation environment meaning that proton, electron flows were

changing into 3 states.

It became clear that proton, electron flow changed into 3 states inside the equation

environment can be expressed as ―3 states of ratio of redoxy potential‖.

It became clear that ratio of redoxy potential is changing into 3 states inside the

equation environment of metabolic reaction meaning that there are 3 states ratio of

membrane structure saturated acid, unsaturated fatty acid:

first occurrence: saturated acid low: unsaturated fatty acid low state,

second occurrence: saturated acid high: unsaturated fatty acid low state,

third occurrence: saturated acid low: unsaturated fatty acid high state.




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Three state new system discovered by such a way was named as ―3 state line of

membrane - redoxy potential‖.

When newly discovered ―3 state line of membrane - redoxy potential‖ named system

is positioned in the middle of two members, called ―carbohydrate, aminoacids, fatty

acids + O2‖, on the left hand side of the equation, it is making full - three membered.

In this case, this equation becomes into the previously non - existent form of

―carbohydrate, aminoacids, fatty acids + 3 state line of membrane - redoxy potential

as very important place of conducting of protons, electrons, starting from

cyanobacteria formed during last 3,8 billion years + O2 = energy (ATP + heat) + H2O

+ CO2‖.

ALMOST ALL PREVIOUSLY UNSOLVED QUESTIONS COMPLETELY

EXPLAINED AND FULLY CLARIFIED

What is the specificity of membrane - redoxy potentials three state line systems of

donators and acceptors, which at first described by us:

1. Consisted of H+, e

- donators as foods and H

+, e

- acceptors as oxygens with direct

participation of a donators of electrons, protons, formed during a events called as big

bang, 15 billion years ago through the process termed as singularity.

2. Ensured normal flow of protons and electrons, formed during a events called as

big bang, 15 billion years ago through the process termed as singularity from




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donators to acceptors with generation of high energy phosphate-ATP, high energy

electrons NADPH and heat energy

3. Functioned with using a glycolysis reaction, Krebs cycle, oxidative deamination of

aminoacids and betta oxidation of fatty acids, oxidation - phosphorylation process to

ensure the energetic demand of organism with direct participation of a donators of

electrons, protons, formed during a events called as big bang, 15 billion years ago

through the process termed as singularity.

4. Provided the normal maintainance of living processes.

5. Existed in three interconvertible states following as:

Liquid alpha state having a high value of oxy potential and consisting mainly of

unsaturated fatty acids, that creates medium level of ATP and high level of heat

energy with direct participation of a donators of electrons, protons, formed during a


singularity.

Solid, beta state having a high value of red potential, consisting mainly of

saturated fatty acids, that creates high level of ATP and medium level of heat energy

with direct participation of a donators of electrons, protons, formed during a events

called as big bang, 15 billion years ago through the process termed as singularity.

Gamma state having a low value of redoxy potential, consisting of low content

of saturated and unsaturated fatty acids, that creates low level of ATP and low level

of heat energy with direct participation of a donators of electrons, protons, formed

during a events called as big bang, 15 billion years ago through the process termed

as singularity.

New postulate, appeared in connection with three state line of membrane

redoxy potential existed between donators and acceptors inside of living cells has

been giving a possibility to radically change following basic aspects as:

Organ formation evolution of morphogenesis with direct participation of a

donators of electrons, protons, formed during a events called as big bang, 15

billion years ago through the process termed as singularity

Refined definition of living processes with direct participation of a donators of

electrons, protons, formed during a events called as big bang, 15 billion years

ago through the process termed as singularity

Refined definition of diabetes and obesity with direct participation of a


billion years ago through the process termed as singularity

Refined definition of security of living body system with direct participation of a


billion years ago through the process termed as singularity.




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WHAT IS COINCIDENCE BETWEEN ABSTRACT THEORY OF RLUNG, MKHRIS,

BADGAN AND THE MEMBRANE - REDOXY POTENTIALS THREE STATE LINE

SYSTEMS EXISTED BETWEEN A DONATORS AND ACCEPTORS OF LIVING

CELLS THAT HAVE BEEN REVEALED BY US?

Fluid alpha state of MS consisting of unsaturated fatty acids with high levels of

oxy potentials conducting the flow of protons and electrons, formed during a events

called as big bang, 15 billion years ago through the process termed as singularity are

associated with abstract theory of Mkhris of Traditional medicine (TM), which is

distinguished by hot, hot oil, acute external characteristics.

Solid betta state of MS consisting of mainly saturated fatty acids conditioning a

high levels of red potentials conducting the flow of protons and electrons, formed


as singularity are associated with abstract theory of Badgan of TM, which is

distinguished by cool, cold oil, stupid external characteristics.

c Gamma state of MS, consisting of decreased contents of saturated -

unsaturated fatty acids, conditioning a decreased levels of redoxy potentials

conducting the flow of protons and electrons, formed during a events called as big

bang, 15 billion years ago through the process termed as singularity are associated

with abstract theory of rlung of TM, which is distinguished by light, mobile, nonoil,

cool external characteristics.

In the result of placing the membrane - redoxy potential three state line systems

enzyme substrate complex between donators - C6H12O6 and acceptors - O2 in the

metabolic equation in the form as C6H12O6 + membrane - redoxy potential three state

line systems enzyme substrate complex + 6O2 = energy + 6H2O + 6CO2 and also

revealing and correcting a omitted third (missing) member in chemical balance

equation for the metabolism of every living cells we suppose the following new model

of functioning of human body in accordince with such metabolic reaction as C6H12O6

+ membrane - redoxy potential three state line systems enzyme substrate complex +

6O2 = energy + 6H2O + 6CO2.

The new model of functioning of human body presents the entry of energy

donators and acceptors through 2,3 compartmens of human body and also energy

exit to 4 compartment, where occur 5 main functions based in 5 membrane structures

of living cells .

How shown in the below drawn picture if in the membrane - redoxy potential

three state line systems enzyme substrate positioned between donators and

acceptors in the left side of the full three membered equation of metabolic reaction

has been prevailed alpha state with high oxygen potentials which followed by more

utilization of donators and high level of consumption of oxygen molecules in the left

side and medium level of ATP, hige level of heat energy, high level of carbon dioxide

formation in the right hand side with coupled change in the energy - substrate entry




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part as change of both donators and acceptors in the tendency to decrease,

increase ratio of HDLP and LDLP in second and third compartments. Also has been

happened paralleled change in the energy - exit i.e.energy utilisation part of living

cells comprising the 5 main functions-5 main membrane structures, expressed as

high depolarisation process in the plasmic membrane, medum level of cell divison in

the nucleous membrane, medium level of synthesis of proteins, lipoproteins in the

ribosome - microsomal membrane complex, formation of more oxidized products in

the microsomal membrane complex, more activity of pereoxisome - lysosome

membrane related functions. They all coded in the theory of Traditional medicine

coded by abstracted thermin as mkhris.




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This above mentioned new theory of existence of three state line of membrane

redoxy potential between donators and acceptors inside of living cells will open up a

broad avenue in modern medical and biological science both in terms of theoretical

innovation as well as applying it in teaching and education practices.

How shown in the above drawn picture if in the membrane - redoxy potential

three state line systems enzyme substrate positioned between donators and


has been prevailed gamma state with low redoxy potentials which followed by slow

utilization of donators and low level of consumption of oxygen molecules in the left

side and low level of ATP, also low level of heat energy, low level of carbon dioxide

formation in the right hand side with coupled change in the energy substrate entry

part as change of Donators and Acceptors in the tendency to very very low level of

maintanance, drcrease both HDLP and LDLP in second and third compartments,

paralleled with three variants of intensity of flow of protons and electrons, formed


as singularity. Meanwhile has been happened paralleled change in the energy exit –

energy utilisation part of living cells comprising the 5 main functions-5 main

membrane structures which appeared as low threshold od rest potential the plasmic

membrane, low level of cell divison in the nucleous membrane, very low level of

synthesis of proteins, lipoproteins in the ribosome - microsomal membrane complex,




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slow formation of both reduced and oxidized products in the microsomal membrane

complex, slow activity of pereoxisome - lysosome membrane related functions,



as singularity. They all coded in the theory of Traditional medicine coded by

abstracted thermin as rlung.

How shown in the above drawn picture if in the membrane - redoxy

potential three state line systems enzyme substrate positioned between donators and


has been prevailed betta state with high reduction potentials which followed by

slow loss of donators and low level of consumption of oxygen molecules in the left

side and high level of ATP, also medium level of heat energy, high level of water

molecule formation in the right hand side with coupled change in the energy

substrate - entry part as change of Donators in the tendency to accumulation,

decrease HDLP and LDLP ratio in second and third compartments. Also has been

happened paralleled change in the energy exit - energy utilisation part of living

cells comprising the 5 main functions - 5 main membrane structures, which appeared

as high level repolarisation potential the plasmic membrane, high level of cell divison

in the nucleous membrane, very high level of synthesis of proteins, lipoproteins in

the ribosome - microsomal membrane complex, increased formation of reduced

products in the microsomal membrane complex, decreased formation of active form

of oxygens in the pereoxisome - lysosome membrane complex, paralleled with three

variants of intensity of flow of protons and electrons, formed during a events called as

big bang, 15 billion years ago through the process termed as singularity... They all

coded in the theory of Traditional medicine coded by abstracted thermin as badgan.

This above mentioned new theory of existence of three state line of membrane

redoxy potential between donators and acceptors inside of living cells will open up a

broad avenue in modern medical and biological science both in terms of theoretical

innovation as well as applying it in teaching and education practices.

In such way if in the membrane - redoxy potential three state line systems

enzyme substrate positioned between donators and acceptors in the left side of the

full three membered equation of metabolic reaction as ―Carbohydrate, aminoacids,

fatty acids + the membrane - redoxy potentials 3 state line systems + 6O2 = energy

(ATP, heat energy) + 6H2O + 6CO2‖ has been prevailed alpha state with high oxygen

potentialshas been created a preconditions to generate the oxidized form of

metabolites and drugs, which in Traditional medicine expressed as hot oil

medicaments and hot oil external characteristics.

This process occurred in following order as first: oxidized form of cytochrom

P450 (CYP) binds the drug any substance, second: NADPH - flavoprotein reductase

system gives (electron is introduced from NADPH via same flavoprotein reductase

system, which reduced the oxidized P 450-drug complex) the proton and electron to




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cytochrom P450-drug binary complex, ―cytochrom P450 (Fe3+++

) - drug binary

complex‖ take reduced form, third: also ―NADPH - flavoprotein reductase system‖

gives the proton and electron to molecular oxygen, reducing, converting it to

activated oxygen form (second electron is introduced from NADPH via same

flavoprotein reductase system, which reduced molecular oxygen and to form a

activated oxygen), fourth: after this formed ―cytochrom P450-drug - activated

oxygen triad complex‖, fifth - this triad complex in turn transfers activated oxygen to

drug substrate and substance to form the the oxidized form of metabolites and drugs.

Also if in the membrane - redoxy potential three state line systems enzyme

substrate positioned between donators and acceptors in the left side of the full three

membered equation of metabolic reaction as ―Carbohydrate, aminoacids, fatty acids

+ the membrane - redoxy potentials 3 state line systems + 6O2 = energy (ATP, heat

energy) + 6H2O + 6CO2‖ has been prevailed betta state with high red potentials has

been created a preconditions to generate the reduced form of metabolites and drugs,

which in Traditional medicine expressed as cool oil medicaments and cool oil

external characteristics.

Meanwile if in the membrane - redoxy potential three state line systems

enzyme substrate positioned between donators and acceptors in the left side of the

full three membered equation of metabolic reaction as ―Carbohydrate, aminoacids,

fatty acids + the membrane - redoxy potentials 3 state line systems + 6O2 = energy

(ATP, heat energy) + 6H2O + 6CO2‖ has been prevailed gamma state with low

redoxy potentials has been created a preconditions to reduce generate both the

reduced and oxidized forms of metabolites and drugs, which in Traditional medicine

expressed as non oil medicaments and dry, mobile, less oil external characteristics.

In such way by us have been proposed the absolutely scientific way to reveal

and correct the one missed member in chemical balance equation for the

metabolism of every living cells by developing the new scientific approaches and

therminology as membrane - redoxy potentials three state line systems of H+, e

-

donators and acceptors, paralleled with three variants of intensity of flow of protons



We are developing the principally new theoretical trend, which are based on

the new knowledge that allows us to explain the essence of more important

biological processes occurred in living cells in the connection with metabolic reaction,

paralleled with three variants of intensity of of protons and electrons, formed during a


singularity.

In case of lacking of this new knowledge we could not develop the new model of

functioning of living cells, relating to harvesting energy from various H,e donators and

acceptors as oxygen.




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We reveal that recently common used metabolic reaction formula of living cell as

C6H12O6 + 6O2 = energy + 6H2O + 6CO2 have been described with missing of one

principally important, inseparable member of this reaction, paralleled with three

variants of intensity of flow of protons and electrons, formed during a events called

as big bang, 15 billion years ago through the process termed as singularity .

In the case of reaction, expressed as C6H12O6 + 6O2 with two member, the formation

of such energy as ATP, heat energy, also end products as H2O, CO2 in the right side

of reaction would not be happened, instead of them glucuronic acid and other

products would be formed as a result of oxidation of glucose molecule ,paralleled

with three variants of intensity of of protons and electrons, formed during a events

called as big bang, 15 billion years ago through the process termed as singularity .

Contrary to it we established that the missed member in chemical balance equation

for the metabolism of every living cells is membrane - redoxy potentials three state

line systems of H+, e

- donators and acceptors, paralleled with three variants of

intensity of flow of protons and electrons, formed during a events called as big


It should be say that the right variant of three membered chemical balance equation

formula for the metabolism is created by putting the membrane - redoxy potentials

3 state line systems of donators and acceptors between C6H12O6 molecule and 6O2

molecule in the left side of reaction.

The correct form of cell metabolic reaction is as follows: ―C6H12O6 + the membrane

- redoxy potentials 3 state line systems + 6O2 = energy (ATP, heat energy) + 6H2O

+ 6CO2‖ i.e.only in this case H2O, and CO2 would be formed, smultuneously with

generation of ATP and heat energy, paralleled with three variants of intensity of flow

of protons and electrons, formed during a events called as big bang, 15 billion years

ago through the process termed as singularity.

What is specificity of membrane - redoxy potentials three state line systems

of donators and acceptors, which at first described by us:

1. Consisted of H+, e

- donators as foods and H

+, e

- acceptors as oxygens,



as singularity.

2. Ensured normal flow of protons and electrons from donators to acceptors with

generation of high energy phosphate - ATP, high energy electrons NADPH and heat

energy paralleled with flow of protons and electrons, formed during a events called

as big bang, 15 billion years ago through the process termed as singularity.




19

3. Functioned with using a glycolysis reaction, Krebs cycle, oxidative deamination of


ensure the energetic demand of organism, paralleled with three variants of intensity

of flow of protons and electrons, formed during a events called as big bang, 15


4. Provided the normal maintainance of living processes, paralleled with three

variants of intensity of flow of protons and electrons, formed during a events called

as big bang, 15 billion years ago through the process termed as singularity.

5. Existed in three interconvertible states as follows:

- Fluid alpha state of membrane structures (MS), consisting of mainly

unsaturated fatty acids, conditioning a high levels of oxy potentials and with high

intensity of proton, electrons conductance and high levels of heat energy release,

middle degree of high energy phosphate - ATP, high energy electrons NADPH, with

increased ratio of accceptors tî donators, paralleled with three variants of intensity

of flow of protons and electrons, formed during a events called as big bang, 15


- Solid betta state of MS, consisting of mainly saturated fatty acids,

conditioning a high levels of red potentials and with slow intensity of proton,

electrons conductance and low levels of heat energy release, high degree of high

energy phosphate - ATP, high energy electrons NADPH, with increased ratio of

donators to acceptors, paralleled with three variants of intensity of flow of protons



- Gamma state of MS, consisting of decreased contents of saturated and

unsaturated fatty acids, conditioning a decreased levels of redoxy potentials with

slow intensity of proton, electrons conductance, also with low levels of heat energy

release and energy accumulation and low degree of high energy phosphate - ATP,

high energy electrons NADPH, with decreased contents of donators and

accceptors, increased loss of proton, electrons prior to generation of proton

gradients, paralleled with three variants of intensity of flow of protons and electrons,


termed as singularity.

What is coincidence between abstract theory of Rlung, Mkhris, Badgan and the

membrane - redoxy potentials three state line systems of donators and acceptors of

living cells, which at first revealed by us:

a. Fluid alpha state of MS, consisting of unsaturated fatty acids with high

levels of oxy potentials are associated with abstract theory of Mkhris of Traditional

medicine (TM), which is distinguished by hot, hot oil, acute external characteristics




20

paralleled with flow of protons and electrons, formed during a events called as big


In this case oftenly provocated a stress reaction related disease, lipid pereoxidation

reaction, paralleled with three variants of intensity of flow of protons and electrons,


termed as singularity.

b. Solid betta state of MS, consisting of mainly saturated fatty acids,

conditioning a high levels of red potentials are associated with abstract theory of

Badgan of TM, which is distinguished by cool, cold oil, stupid external

characteristics. In this case oftenly provocated the pathology as diabetes mellitus,

obesity, hypercholesterinemia, paralleled with three variants of intensity of flow of

protons and electrons, formed during a events called as big bang, 15 billion years


c. Gamma state of MS, consisting of decreased contents of saturated –

unsaturated fatty acids, conditioning a decreased levels of redoxy potentials are

associated with abstract theory of rlung of TM, which is distinguished by light,

mobile, nonoil, cool external characteristics In this case oftenly provocated the

pathology as hypothrophy, anemia, paralleled with three variants of intensity of flow

of protons and electrons, formed during a events called as big bang, 15 billion years


New definition of living cells according to new integrated triple medical system

- NCM which at first developed by us:

Living cells are functional - structural unit of human body, consisting from

membrane - redoxy potentials three state line systems, which ensure constant

flow of electrons and protons between Donators and Acceptors with producing

high energy phosphate - ATP, high energy electrons - NADPH, heat energy,

thereby able to maintain normal occuring of information - response function in

plasmic membrane, genetic - cell division function in nucleus membrane,

biotransformation function in microsomal membrane and biosynthetic -

rebiosynthetic function in ribosome - microsomal and lisosomo - pereoxisamal

membrane, bioenergetical function in mitochondrial membrane, beside all their

important molecules have general “nucleoside + phosphate” structures.

6. Owing to ascertaining the scientific essence of the theories such as Chinese Yin-

Yan; Sasang constitution types - Tae-eumin, So-eumin, and So-yangin; Rlung-Mkhis-

Badgan or Lung-Ti-Badgan of Tibetan-Mongolian traditional medicine and Vatta -

Pitta-Kappa of Ayurved in India, the bases for administration and treatment of the

Oriental medicine tendency to explain some unclear issues that cannot be solved

through the contemporary medicine is expanded. Aim of study: To study the

relationship between some physiological, biochemical parameters of membrane -




21

redoxy potentials 3 state line system with the human constitutional types of the

Traditional Medicine. Results: The contents of saturated fatty acid in visceral fat

(paralleled with three variants of intensity of flow of protons and electrons, formed


as singularity) of Badgan symbolic code (SC) group - was increased with statistical

difference in comparison to Mkhris symbolic code (SC) group and Rlung symbolic

code (SC) group. The membrane resistance capacity of Badgan SC group was

increased with statistical difference compared between MSC group and RSC group

(paralleled with three variants of intensity of flow of protons and electrons, formed


as singularity). MDA of erythrocyte membrane of BSC group decreased with

statistical difference in comparison to MSC group and the RSC group.

Conclusions: Our study was defined the the basic three form of membrane redoxy

potential three state lines, conducting a flow of protons and electrons, formed during

a events called as big bang, 15 billion years ago through the process termed as

singuiarity are existed in link with the human constitutional types as like abstractly

coded codifications of rlung, mkhis, badgan of the Traditional Medicine.

SECOND PART

s-NCM KNOWLEDGE MAY BE DESCRIBED IN FOLLOWING ORDERS:

1. s-NCM knowledge show that this process as the newborn universe expanded (15

billion-bya years ago), within 3 minutes protons and neutrons had formed and joined

to make atomic nuclei, after 100 000 years electrons joined to the nuclei to form

atoms give the beginning to form a membrane redoxy potential three state lines in

all living cells

2. s-NCM knowledge show that this process as in less than a billion years may be

3,6 bya - life on earth was established owing to a flow of protons and electrons,


termed as singularity with a participation of a membrane redoxy potential three state

lines

3. s-NCM knowledge show that in this connection had been formed a special

structures as membrane redoxy potential three state lines in all living cells,

conducting a flow of protons and electrons, formed during a events called as big


4. s-NCM knowledge show that the basic three form of membrane redoxy potential

three state lines in all living cells, conducting a flow of protons and electrons, formed




22


as singuiarity are existed in link and coded by codifications as rlung, mkhis, badgan

of the Traditional Medicine.

THIRD PART

The link between a Dala Lama theachings relating to Integrated Medical Systems,

consisting of Traditional and Modern medicine has been implemented eventually

through the proposed by us the s-NCM knowledge, which reflected in the teaching of

H.H.Dalai Lama as …Without mixing the two approaches, and without saying one is

better than the other, both schools should work together in order to find ways of

understanding each other and thus boost the effectiveness of the two healing

techniques‖.

The s-NCM knowledge demonstrate that the basic three form of membrane redoxy

potential three state lines, existing in all 14 trillion living cells, conducting a flow of

protons and electrons, formed during a events called as Big Bang, 15 billion years

ago through the process termed as singularity are coded by codifications as rlung,

mkhis, badgan of the Traditional Medicine and serves the role of … ways of

understanding each other…how says H.H.Dalai Lama.

FOURTH PART

THE DEFINITION OF NCM MEDICINE

Definition of NCM-newly coded medicine.

NCM-newly coded medicine is triple medical system, composed of Traditional

Medicine (TM) in the full form, also Modern medicine (MM) in the full form and in

addition s-NCM new knowledge based medicine (NKBM), implemented a every

day diagnostic and treatment functions by using a three kind approaches as TM, MM,

NKBM together, and their scientific-theoretical basis is strongly connected with s-

NCM new knowledge as new definition of living cells, completely explaining the

essence of normal existence of living cells and simultaneously revealing and

discovering the essence of basic theoretical aspects of Traditional Medicine and

Modern medicine, not allowing the mixing and neutralizing theoretical aspects of both

medicine, preserving the unique specificity of their theoretico-practical aspects and

therminological specifics, meanwhile not separating each other.

Definition of Traditional medicine.

Owing to foundation of NCM medicine became clear that such very important

regulations as gene in the one side, Rlung, Mkhris, Badgan in the another side, also




23

such scientific knowledge as genetics and Traditional medicine existed in the one

unseparable cognitive chains, consisting of whole 6 steps, started by gene regulation

in the 1 step - ended by Rlung, Mkhris, Badgan coding in the therminal sixth step

because of nonexistence human species as ―Homo sapiens plus rlung, mkhris,

badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan, yin‖ as if

containing the 14 trillion living rlung, mkhris, badgan, yin, yan along with 14 trillion

living cells only postulated by Traditional medicine doctors, all their diagnostic and

treatment methods based in this form of human specie.

NCM - medicine is the integrated medical system, consisting of Traditional and

Modern Medicines scientifically connected with each other through the s-NCM

new knowledge, which has a following specific characters:

1. NCM medicine categorically refused the coexistence the opinions, relating to

coexistence of ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata,

kapha, pitta‖, ―Homo sapiens plus yan, yin‖ human species (human species,

containing a living rlung, mkhris, badgan, yin, yan are not registered in Linnaean

taxonomy) along with ―Homo sapiens‖ human specie.

2. NCM medicine postulated that the life was became strongly dependent from the

presence of protons and electrons, which were formed during a events called as big

bang, 15 billion years ago by creating the reaction as ―Carbohydrate, aminoacids,

fatty acids + 3 state line of membrane - redoxy potential + O2 = energy (ATP + heat)

+ H2O + CO2‖ facilitating the flow of protons and electrons with help of 3 state line of

membrane - redoxy potential.

3. NCM medicine postulated that the Diagnosis and treatment, including a Traditional

and Modern medicine should be based on the morpho - functional unit, which really

are existed inside a human body, which we can see and measure as three state line

system of membrane - redoxy potential dependent systems, including 4

compartments and 10 functional systems of human body.

4. NCM medicine postulated that inside a human body are existed protons and

electrons, proton - electron dependent systems, also proton - electron delivery

systems, proton - electron utilizing systems.

5.1. NCM medicine postulated that inside a human body are not existed vata, kapha,

pitta, rlung, mkhris, badgan, which we can not see and measure.

5.2. NCM medicine firstly reveal the missed member as 3 state line of membrane -

redoxy potential as very important place of conducting of protons, electrons, starting




24

from cyanobacteria formed during last 3,8 billion years in the reaction as‖

carbohydrate, aminoacids, fatty acids +3 state line of membrane - redoxy potential +

O2 = energy (ATP + heat) + H2O + CO2‖

6. NCM medicine find the three state new metabolic system functioned in the level of

all living cells and at first give the name as ―3 state line of membrane - redoxy

potential‖ existed in all 14 trillion cells.

7. NCM medicine postulated that the the basic three form of membrane redoxy

potential three state lines in all 14 trillion living cells, conducting a flow of protons and

electrons, formed during a events called as big bang, 15 billion years ago through the

process termed as singularity are existed in link and coded by codifications as rlung,

mkhis, badgan of the Traditional Medicine.

8. NCM medicine postulated that membrane - redoxy potentials three state line

systems of donators and acceptors, which at first described by us consisted of H+, e

-

donators as foods and H+, e

- acceptors as oxygens with direct participation of a

donators of electrons, protons, formed during a events called as big bang, 15 billion

years ago through the process termed as singuiarity. ensured normal flow of protons


through the process termed as singuiarity from donators to acceptors with generation

of high energy phosphate-ATP, high energy electrons NADPH and heat energy,

functioned with using a glycolysis reaction, Krebs cycle, oxidative deamination of


ensure the energetic demand of organism with direct participation of a donators of

electrons, protons, formed during a events called as big bang, 15 billion years ago


9. NCM medicine postulated that all theoretical, diagnostic, treatment questions of

Traditional medicine should find its scientific explanations in the ―Homo sapiens‖

human specie in the level of three state line system of membrane - redoxy potential

dependent systems existed in 14 trillion cells ncluding 4 compartments and 10

functional systems of human body.

10. In such way it was created integrated medical system, named as NCM medicine,

consisting of Traditional and Modern Medicines, connected with each other through

s-NCM new knowledge, how says H.H.Dalai Lam as …without mixing the two

approaches, and without saying one is better than the other, both schools should

work together in order to find ways of understanding each other and thus boost the

effectiveness of the two healing techniques and also from our side not changing any

words, dot, strongly preserving the unrepeated unique of Traditional medical




25

knowledge heritages, using s-NCM new knowledge as key point to ensure the free

circulation of two various non identical to each other knowledge of two medicines and

the new knowledge as knowledge relating to 4 compartments and the new

knowledge about 10 functional systems of human body, abstracted and coded by

thermins as vata, pitta, kapha, yin, yang, badgan, mkhris, rlung.

The really exixtence of ―3 state line of membrane - redoxy potential‖ named system

is positioned in the middle of two members, called ―carbohydrate, aminoacids, fatty

acids + O2‖, the previously non - existent form of ―carbohydrate, aminoacids, fatty

acids + 3 state line of membrane - redoxy potential as very important place of

conducting of protons, electrons, starting from cyanobacteria formed during last 3,8

billion years + O2 = energy (ATP + heat) + H2O + CO2 in 14 trillion cells of Homo

sapience confirmed by the similarity of aerob oxidation and photosynthesis:

1. In both cases occurred АTP synthesis from и АDP and Pi

2. Both cases are conducted with coupling with a flow of electrons in respiration

chain

3. In both cases to be coupling of the flow of electrons in respiration chain with

phosphorylation had been needed the special organized structures as cristae in case

of mitochondria, thialokoids in case of chloroplasts (Д.Тейлор и др, Биология, 3

том, стр.345).

Rules of noncoincidences:

1. The noncoincidence of theoretical basis of diagnosis and treatment of Traditional

medicine with a lawfull processes of development of life process by the law of

evolutionary approved system with duration of 3,8 billion years beginning from

cyanobacteria ending by Homo sapiens, which were characterized by functioning

with using a glycolysis reaction, Krebs cycle, oxidative deamination of aminoacids

and betta oxidation of fatty acids, oxidation - phosphorylation process to ensure the

energetic demand of organism with direct participation of a donators of electrons,

protons, formed during a events called as big bang, 15 billion years ago through the

process termed as singularity with the participation of basic metabolic reaction as




+ CO2 in 14 trillion cells of Homo sapience.

2. The noncoincidence of theoretical basis of diagnosis and treatment of Modern

medicine with a lawfull processes of development of life process by the law of

evolutionary approved system with duration of 3,8 billion years beginning from






26








+ CO2 in 14 trillion cells of Homo sapience.

3. It should to make the scientific basis in order to create the coincidence of

theoretical basis of diagnosis and treatment of Modern medicine with a lawfull

processes of development of life process by the law of evolutionary approved system

with duration of 3,8 billion years beginning from cyanobacteria ending by Homo

sapiens, which were characterized by functioning with using a glycolysis reaction,

Krebs cycle, oxidative deamination of aminoacids and betta oxidation of fatty acids,

oxidation - phosphorylation process to ensure the energetic demand of organism with

direct participation of a donators of electrons, protons, formed during a events called

as big bang, 15 billion years ago through the process termed as singularity with the

participation of basic metabolic reaction as ―carbohydrate, aminoacids, fatty acids + 3

state line of membrane - redoxy potential as very important place of conducting of

protons, electrons, starting from cyanobacteria formed during last 3,8 billion years +

O2 = energy (ATP + heat) + H2O + CO2 in 14 trillion cells of Homo sapience.

4. It should to make the scientific basis in order to create the coincidence of

theoretical basis of diagnosis and treatment of Traditioal medicine with a lawfull

processes of development of life process by the law of evolutionary approved system

with duration of 3,8 billion years beginning from cyanobacteria ending by Homo

sapiens, which were characterized by functioning with using a glycolysis reaction,

Krebs cycle, oxidative deamination of aminoacids and betta oxidation of fatty acids,

oxidation - phosphorylation process to ensure the energetic demand of organism

with direct participation of a donators of electrons, protons, formed during a events

called as big bang, 15 billion years ago through the process termed as singularity

with the participation of basic metabolic reaction as ―carbohydrate, aminoacids, fatty

acids + 3 state line of membrane - redoxy potential as very important place of


billion years + O2 = energy (ATP + heat) + H2O + CO2 in 14 trillion cells of Homo

sapience.

First interpretation: if in the system of of ―3 state line of membrane - redoxy potential‖

named system is positioned in the middle of two members, called ―carbohydrate,

aminoacids, fatty acids + Î2‖ were prevailed gamma state with slow redoxy potentials




27

the intensity of formation of end products and the degree of utilization of electron-

proton donators, acceptors would be take the another character - ATP synthesis

become below than 160 kg per 24 hours, the generation of heat energy to warming

the all waters and fluids from zero to 37 degree per 24 hours become below, the

formation of metabolic water needed to protonisation of fumarat to malat in the Krebs

cycle become below than180 ml, the formation of carbon dioxide become below than

288 l in case the person has been used 2 kg food as electron - proton donators and

432 liter oxygen as electron - proton acceptors as normally, which coded in the

Traditioal medicine by thermin as vata, rlung.

Second interpretation: if in the system of of ―3 state line of membrane - redoxy

potential‖ named system is positioned in the middle of two members, called

―carbohydrate, aminoacids, fatty acids + O2‖ were prevailed alpha state with high

oxy potentials the intensity of formation of end products and the degree of utilization

of electron - proton donators, acceptors would be take the other character - ATP

synthesis become below than 160 kg per 24 hours, but the generation of heat energy

to warming the all waters and fluids from zero to 37 degree per 24 hours become

high, the formation of metabolic water needed to protonisation of fumarat to malat in

the Krebs cycle become below than 180 ml, the formation of carbon dioxide become

high than 288 l in case the person has been used 2 kg food as electron - proton

donators and 432 liter oxygen as electron - proton acceptors as normally, which

coded in the Traditioal medicine by thermin as pitta, mkhris.

Third interpretation: if in the system of of ―3 state line of membrane - redoxy potential‖

named system is positioned in the middle of two members, called ―carbohydrate,

aminoacids, fatty acids + Î2‖ were prevailed betta state with high red potentials the

intensity of formation of end products and the degree of utilization of electron - proton

donators, acceptors would be take the also opposite character - ATP synthesis

become more than 160 kg per 24 hours, but the generation of heat energy to

warming the all waters and fluids from zero to 37 degree per 24 hours become

below, the formation of metabolic water needed to protonisation of fumarat to malat

in the Krebs cycle become high than180 ml, the formation of carbon dioxide become

below than 288 l in case the person has been used 2 kg food as electron - proton

donators and 432 liter oxygen as electron - proton acceptors as normally, which

coded in the Traditioal medicine by thermin as kapha, badgan.

In such way it was interesting that the three variants of the velocity of flow of

electrons and protons from electron - proton donators to oxygen as electron -proton

acceptors along the ―3 state line of membrane - redoxy potential‖ named system is

positioned in the middle of two members, called ―carbohydrate, aminoacids, fatty





28

acids + 3 state line of membrane - redoxy potential + O2‖ as slow - middle - fast and

the three variants of the formation of ATP in the ―3 state line of membrane - redoxy

potential‖ named system is positioned in the middle of two members, called

―carbohydrate, aminoacids, fatty acids + O2‖, the previously non - existent form of


+ O2‖ as below - middle - high, also the three variants of the formation of heat

energy in the ―3 state line of membrane - redoxy potential‖ named system is

positioned in the middle of two members, called ―carbohydrate, aminoacids, fatty


acids + 3 state line of membrane - redoxy potential + O2‖ as below - middle - high

coded in the Traditional medicine by thermin as vata, kapha, pitta, rlung, mkhris,

badgan, yan, yin.

WHAT IS THE NEW KNOWLEDGE ABOUT BASIC 4 COMPARTMENTS OF

HUMAN BODY

According to our suggestion the new model of functioning of human body

presents the entry of energy donators and acceptors through 2, 3 compartmens of

human body and also energy exit to 4 compartment, where occur 5 main functions

based in 5 membrane structures of living cells.

The basic 4 compartments of human body can be divided as the left hand side

of the equation dependent (Carbohydrate, aminoacids, fatty acids + 3 state line of

membrane - redoxy potential as very important place of conducting of protons,

electrons, starting from cyanobacteria formed during last 3,8 billion years + O2 =

energy (ATP + heat) + H2O + CO2 - reaction medium) compartment as the Fourth

compartment and the right hand side of the equation dependent compartments as

First compartment, Second compartment and Third compartment.

First compartment is the compartment of normal functioning of ―Carbohydrate,

aminoacids, fatty acids + 3 state line of membrane - redoxy potential as very

important place of conducting of protons, electrons, starting from cyanobacteria

formed during last 3,8 billion years + O2 = energy (ATP + heat) + H2O + CO2 -

reaction medium in 14 trillion living cells of human body.

Second compartment is the compartment of delivering electron-proton

acceptors as oxygen and electron - proton donators as food together to 14 trillion

living cells to maintain the normal functioning of ―Carbohydrate, aminoacids, fatty

acids + 3 state line of membrane-redoxy potential as very important place of


billion years + O2 = energy (ATP + heat) + H2O + CO2 - reaction medium.




29

Third compartment is the compartment of preservingof electron - proton donators

food in the form of visceral and subcutaneous fatty acids to maintain the normal

functioning of ―Carbohydrate, aminoacids, fatty acids + 3 state line of membrane -


from cyanobacteria formed during last 3,8 billion years + O2 = energy (ATP + heat) +

H2O + CO2 -reaction medium in 14 trillion living cells of human body.

Fourth compartment is the energy, metabolites (ATP + heat + H2O + CO2) formed in

the first compartment utilisation part of living cells comprising the 5 main functions-5

main membrane structure complex as information - response functions,

depolarization - repolarization processes in the plasmic membrane, genetic - cell

divison processes in the nucleous membrane, the synthesis, resynthesis of proteins,

lipoproteins in the ribosome - microsomal membrane complex, the bioenergetical

processes in the mitochondrial membrane complex, the bioconverting,

biotransforming processes in the microsomal membrane complex, synthesis,

resynthesis and activated oxygen dependent processes of pereoxisome - lysosome

membrane complex.

WHAT IS THE NEW KNOWLEDGE ABOUT 10 BASIC FUNCTIONAL SYSTEMS

OF HUMAN BODY

Our new classification named as 10 basic functional systems of human body

strongly connected with a lawfull processes of development of life process by the law

of evolutionary approved system with duration of 3,8 billion years beginning from










+ CO2 in 14 trillion cells.

In such way our new classification named as 10 basic functional systems of

human body has some principally difference from modern classic anatomy

classification of human body, based in the Andreas Vesalis classification

(1514-1564)




30

1. First functional system is the system delivering electron - proton donators as food

to 14 trillion living cells to maintain the normal functioning of ―Carbohydrate,




reaction medium, identical to Gastroenterological system.

2. Second functional system is the system delivering electron - proton acceptors as

oxygen to 14 trillion living cells to maintain the normal functioning of ―Carbohydrate,




reaction medium, identical to Respiratory system.

3. Third functional system is the system delivering electron - proton acceptors as

oxygen and electron - proton donators as food together to 14 trillion living cells to

maintain the normal functioning of ―Carbohydrate, aminoacids, fatty acids + 3 state

line of membrane - redoxy potential + O2 = energy (ATP + heat) + H2O + CO2 -

reaction medium, identical to Cardiovascular system.

4. Fourth functional system is the system eliminating and neutralizing toxic

metabolites and carbon dioxide formed during the functioning of the reaction medium

as ―Carbohydrate, aminoacids, fatty acids + 3 state line of membrane-redoxy

potential + O2 = energy (ATP + heat) + H2O + CO2 - identical to Renal - urinary and

Acid-Base controlling system.

5. Fifth functional system is the system ensuring the converting some toxic metabolic

products to normal metabolic products and conducting the synthesis and resynthesis

of saturated and unsaturated fatty acids as main components of membrane

structures belong to 3 state line of membrane - redoxy potential system as

―Carbohydrate, aminoacids, fatty acids + 3 state line of membrane - redoxy potential



+ CO2 reaction medium existed in 14 trillion living cells - identical to Hepato - billiary

system.

SECOND PART

HISTORICAL AND PRACTICAL ASPECTS OF NCM MEDICINE

The reason why the theory of Traditional medicine should be explained in the

level of membrane - redoxy potential 3 state line dependent systems as 4

compartments and 10 functional systems comprising all 14 trillion cells of human

body, it is connected with these facts that there are not really existed a human




31

species as ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata,

kapha, pitta‖, ―Homo sapiens plus yan, yin‖ as if containing the 14 trillion living rlung,

mkhris, badgan, yin, yan along with 14 trillion living cells only postulated by

Traditional medicine doctors , all their diagnostic and treatment methods based in

this form of human specie, but categorically resisted, refused by NCM medicine.

Now it is very appropriate time to solve all problems of medicine, relating to the

normal existence, disturbance of normal existence of human body, their diagnosis

and treatmen by using fully membered metabolism equition, which include a G

knowledge of Traditional medicine + X - knowledge of Traditional medicine + S -

knowledge of Modern medicine + s-NCM knowledge of NCM medicine.

In recent years, a renewed interest and attention by many scientists of our and

foreign countries are directed towards the establishment of scientific essence of

theoretical problems of Tibetian-Mongolian Traditional Medicine (TMMT) in strong

connection with theory of Contemporary Biology and Medicine. An number of these

theoretical problems belongs the theory of five elements and three elements (rlung,

Mkhris, Badgan), In this connection a question rise what interorganism's

microstructure play the role of real material, objective Substance, which leads to the

appearance of Universal theory of five elements and three etements-rLung. mkhrisk

badgan. i.e the external properties of what structure had perceived and Summarized

as General characteristics of rLung, mrkris, badgan In 1990 the author using

comparative Analysis methods demonstrated for the first time and eventually

confirmed that, wholeorganism's Membrane structure, existing in the three Basic

States as Fluid-alpha state, Crystall-solict state, and ffuid-crystalf intermediate

gamma state can play the role of such biological substance i.e. Betta state of

membrane structure (MS) -it's external functional properties corresponds to abstract

notion of Badgan, alpha state of MS-it's functional external properties summarized

under abstract notion of Mkhris, and Intermediate Gamma state of MS, external

functional properties of which is symbolized under the abstract notion of rLung by

proposing the new knowledge based model of living cells.

Main chronical stage of appearance of new conception “The coincidence of

Rlung, Mkhris, Badgan abstract thermin with regulation occurred in membrane

- redoxy potentials 3 state systems of living cells.

We since 1990 year has been developed ―working hypothesis‖, according to it, inside

human body have been the functioned a unknown structural - functional unit, coded

by vata, kapha, pitta, rlung, mkhris, badgan, yin, yan which has a following specifics:

1. In human body, during 24 hours this unknown structural - functional unit three

times subjected to absolutely opposite 3 state change, in the morning existed in the




32

state, coded by Rlung thermin, in the midday existed in the state, coded by Mkhris

thermin, in the evening existed in the state, coded by Badgan thermin.

2. In human body, during whole year this unknown structural - functional unit three

times subjected to absolutely opposite 3 state change coded by Rlung, Mkhris,

Badgan abstract thermin, in the spring existed in the state, coded by Rlung thermin,

in the autumn in the state, coded by Mkhris thermin, in the summer existed in the

state, coded by Badgan thermin.

3. The human body this unknown structural - functional unit subjected to absolutely

opposite 3 state change during phylogenesis, in the child age existed in the state,

coded by Badgan thermin, in young in the state, coded by pitta, mkhris thermins, in

the old existed in the state, coded by Rlung thermin.

4. The human body this unknown structural - functional unit subjected to absolutely

opposite 3 states coded by Rlung, Mkhris, Badgan abstract thermin depending the

compositions of horse, sheep, goat, marmot meats.

5. The individuals are born with excess one of three constitutions, which are coded

by Rlung, Mkhris, Badgan abstract thermin.

6. The human body this unknown structural - functional unit subjected to a absolutely

opposite 3 states coded by Rlung, Mkhris, Badgan abstract thermin under influence

of medicaments.

7. The general mecchanism of healthy existence of human body are due to normal

balance of this unknown structural - functional unit with 3 basic states, which coded

by Rlung, Mkhris, Badgan abstract thermin under influence of medicaments.

8. The individuals with excess one of this unknown structural - functional unit with 3

basic states, which coded by Rlung, prone to loss of body weight, the individuals with

excess one of this unknown structural - functional unit with 3 basic states, which

coded by Mkhris prone to excess of body heat, the individuals with excess one of

this unknown structural - functional unit with 3 basic states, which coded by Badgan,

prone to excess gain of body weight.

In this time we can not find a literature information, experimental data, describing the

existence of about this structural - functional unit with 3 basic states, which during 24

hours three times subjected to absolutely opposite 3 states, which during whole year

three times subjected to a absolutely opposite 3 states, which during whole year

three times subjected to absolutely opposite 3states, which are subjected to

absolutely opposite 3 states under influence of medicaments, which are subjected to

absolutely opposite 3 states during phylogenetic development of human body.

Because of this situation we conduct investigation under isolated cell

population, during which we establish that:




33

a. The response of cells to stimulus was various in the morning coded by Rlung

thermin, also in the midday coded by Mkhris thermin, beside in the evening, coded by

Badgan thermin.

b. Became clear that the main structures of living cells, which subjected to daily three

state change may be membrane structures existed in 14 trillion cells.

3. Also became clear that fluid alpha, solid betta and intermediate gamma state

of membrane structures are subjected to daily, seasonal, phylogenetic,

medicament and food depending changes.

Based in theses results we came to conclusion that:

1. In human body, during 24 hours fluid alpha, solid betta and intermediate gamma

state of membrane structuresof 14 trillion cells have been subjected three times to

absolutely opposite 3 states, in the morning dominated the gamma state of

membrane structures, coded by Rlung thermin, meanwhile in the midday prevailed

the fluid alpha state, coded by Mkhris thermin, in the evening prevailed the solid betta

state, coded by Badgan thermin.

2. In human body, during whole year fluid alpha, solid betta and intermediate gamma

state of membrane structures are three times subjected to absolutely opposite 3

states coded by Rlung, Mkhris, Badgan abstract thermin, in the spring dominated the

gamma state, coded by Rlung thermin, in the autumn elevated the fluid alpha state

state, coded by Mkhris thermin, in the summer increased the solid betta state state,

coded by Badgan thermin.

3. The human body alpha, solid betta and intermediate gamma state of membrane

structures subjected to absolutely opposite 3 states during phylogenesis, in the child

age dominated the solid betta state state, coded by Badgan thermin, in young age

dominated the fluid alpha state, coded by Mkhris thermin, in the old age dominated

the intermediate gamma state state, coded by Rlung thermin.

4. The human body subjected to absolutely opposite 3 states coded by Rlung,

Mkhris, Badgan abstract thermin depending the compositions of horse, sheep, goat,

marmot, beef meats. The eating of horse, marmot meats resulted to increase of fluid

alpha state with high level of oxidation potentials, coded by Mkhris thermin, take of

beef meats resulted to increase of solid betta state with high level of reduction

potentials, coded by Badgan abstract thermin, take of lean goat meats resulted to

increase of gamma state with low level of oxidation-reduction potentials, coded by

rLung abstract thermin.

5. The individuals are born with excess one of three constitutions, which are coded

by in one case by Rlung abstract thermin, in another case by Mkhris, in third case by

Badgan abstract thermin.

6. The human body subjected to absolutely opposite 3 states coded by Rlung,

Mkhris, Badgan abstract thermin under influence of medicaments.




34

7. The general mecchanism of healthy existence of human body are due to normal

balance of 3 basic states as ―gamma state with low level of oxidation - reduction

potentials and solid betta state with high level of reduction potentials, addition to

these fluid alpha state with high level of oxidation potentials‖, which coded by Rlung,

Mkhris, Badgan abstract thermin.

8. The individuals are born with excess of gamma state with low level of oxidation -

reduction p, which coded by Rlung, prone to loss of body weight, the individuals are

borned with excess of fluid alpha state with high level of oxidation potentials‖, which

coded by Mkhris prone to excess of body heat, the individuals are borned with

excess of solid betta state with high level of reduction potentials, which coded by

Badgan, prone to excess gain of body weight.

Definition of Mkhris abstract thermin.

Abstract Mkhris thermin showed:

a. Relatively high level of fluid alpha states, consisting of unsaturated fatty acids with

high levels of oxy potentials and with high levels of proton, electrons conductance

and high levels heat energy release, middle degree of energy accumulation and

middle degree of high energy phosphate-ATP, high energy electrons NADPH, with

middle ratio of donators: accceptors are associated with abstract theory of Mkhris,

which is distinguished by hot, hot oil, acute external characteristics.

b. The change of fourth compartment parameters where some metabolites formed in

the result of functioning of 5 membrane structures-5 function systems, ensuring

normal genetic - cell division, information - response, biosynthetical, bioenergetical,

biotransformation functions by using of high energy phosphate-ATP, high energy

electrons NADPH and heat energy turned to form of increase of formation of oxidized

form of metabolites, increase of heat energy, increase of depolarization, decrease of

repolarisation there are coded by abstract Mkhris code in the Tibetian Mongolian

Traditional medicine.

c. The change of second compartment parameters consisting of serum and

extracellular system, where donators, acceptors and some metabolites timely

reserved turned to form of decrease of ratio of donators and acceptors, also

increase of AO protection system - increase of SPOL system there are all coded by

abstract Mkhris code ccode in the Tibetian Mongolian Traditional medicine.

d. The change of Third compartment parameters in the form of increase of

unsaturated class of visceral and external under skin fatty acids, also decrease of

donators, increase of acceptors are coded by abstract Mkhris code in the Tibetian

Mongolian Traditional medicine.

Definition of Badgan abstract thermin.

Abstract Badgan thermin showed:




35

a. Relatively high level of solid betta state, consisting of mainly saturated fatty acids,

conditioning a high levels of red potentials and with slow levels of proton, electrons

conductance and low levels of heat energy release, high degree of energy

accumulation and high degree of high energy phosphate-ATP, high energy electrons

NADPH, with increased ratio of donators : accceptors are associated with abstract

theory of Badgan, which is distinguished by cool, cold oil, stupid external

characteristics.



normal genetic-cell division, information-response, biosynthetical, bioenergetical,


electrons NADPH and heat energy turned to form of increase of formation of

reduced form of metabolites, decrease of heat energy, decrease of depolarization,

increase of repolarisation there are coded by abstract Badgan code in the Tibetian


c. The change of Third compartment parameters in the form of increase of saturated

class of visceral and external under skin fatty acids, also increase of donators,

decrease of acceptors are coded by abstract Badgan code in the Tibetian Mongolian


d. The change of second compartment parameters consisting of serum and

extracellular system, where donators, acceptors and some metabolites timely

reserved turned to form of increase of ratio of donators and acceptors, also

increase of AO protection system - decrease of SPOL system there are all coded by

abstract Badgan code in the Tibetian Mongolian Traditional medicine.

Definition of Rlung abstract thermin.

Abstract Rlung thermin showed:

a. Relatively high level of gamma state, consisting of decreased contents of

saturated-unsaturated fatty acids, conditioning a decreased levels of redoxy

potentials and with slow levels proton, electrons conductance and low levels of heat

energy release and energy accumulation and low degree of high energy phosphate-

ATP, high energy electrons NADPH, with decreased contents of donators:

accceptors, increased significance of proton, electrons prior to generation of proton

gradients, prevailed slip mecchanism are associated with abstract theory of rlung,

which is distinguished by light, mobile, nonoil, cool external characteristics.



normal genetic-cell division, information-response, biosynthetical, bioenergetical,





36

electrons NADPH and heat energy turned to form of increase of formation of reduced

and oxidized form of metabolites, decrease of heat energy, change of ratio of

depolarization and repolarisatio processes there are coded by abstract rLung code in

the Tibetian Mongolian Traditional medicine.

c. The change of second compartment parameters consisting of serum and

extracellular system,where donators, acceptors and some metabolites timely

reserved turned to form of decrease of contents of donators and acceptors also

decrease of AO protection system - decrease of SPOL system there are all coded by

abstract rLung ccode in the Tibetian Mongolian Traditional medicine.

d. The change of Third compartment parameters in the form of decrease of

saturated class of visceral and external under skin fatty acids, also decrease of

donators, decrease of acceptors are coded by abstract rLung code in the Tibetian


A number of these theoretical problems belongs the theory of five element and

the theory rlung, Mkhris, Badgan.

In this connection a question rises what interorganism's microstructure related

morpho-functional unit i.e. new knowledge based model of living cells plays the

role of real material, objective substance, which leads to the appearance of universal

theory of five elements and rlung, mkhris badgan. i.e. the external properties formed

in which morpho - functional unit, structure, revealed by new knowledge, had

perceived and summarized as general characteristics of rlung, mkhris, badgan (so

named X- knowledge), so named 20 external patterns (so named G- knowledge) in

traditional medicine 3000 years ago.

And so, recently scientists from many countries are remained, not able to find this

whole organisms unique functional - structural bioequivalents, to propose the new

model of living cells, which was reflected in the theory of rlung, Mkhris, Badgan,

which in three forms of existence can be show all the external signs as hot, cold,

heavy, mobile summarized and abstractized by wind like rlung, fire-sun like mkhris

and water-moon like Badgan thermin.

There are reasons to say that the appearing of abstract theory of Rlung, Mkhris,

Badgan in Tradititional medicine 3 thousand years ago - follow from the functioning

of membrane - redoxy potentials three state line systems in the first compartment

with close relationship with fourth and second, third compartments in human body,

revealed by s-NCM new knowledge based model of living cells.

To decide a main logical cognitive key points of research works, directed to find the

scientifico-methodological basis of Newly Coded Medicine (NCM) was planned to

conduct the our study in such interconnectable ways:




37

1. The first principally important step of our works was a detection of evolutionary

very important - constantly developed general characteristics of living cells, which

may be reflected in the theory of rlung, mkhris, badgan of Tibetan Mongolian


2. The second principally important step of our works was a revealing the functional

and structural unit of living cells, which may be reflected in the theory of Tibetian -

Mongolian Traditional medicine in the following philosophical context as wind - like

mobile, unoilly, light nature - external characteristics of human body, symbolized by

rlung abstract thermin, sun - like hot, hot oilly nature - external characteristics of

human body, symbolized by mkhris abstract thermin, moon - like cool, heavy, cold

oily nature - external characteristics of human body, symbolized by badgan abstract

thermin.

3. The next principally important step of our works was establish a scientific basis of

new enriched definition of living cells, which are included the functional and structural

unit of living cells of human body, which may be expressed in the theory of Tibetan

Mongolian Traditional medicine by abstract thermins as rlung, mkhris, badgan.

Considering the above mentioned general line of wide scale investigations and

difficulties in the studying of theory of Traditional Medicine, we are setting the

following concrete goals:

- To reveal this material substances, which existed inside of human body and

conditioned all external signs of "rlung, Mkhris, Badgan" according to theory of

Traditional Medicine /TM/, revealed by s-NCM new knowledge based model of

living cells

To establish scientific matter of abstract notion of (rlung, Mkhris, Badgan),

regarding to the age, season, diets, signs and causes of disease, 'specificity of solid

organs and individuals in close connection with the functional properties, which

formed on the level of "such material substances", revealed by s-NCM new

knowledge based model of living cells .

To elaborate the new principles of prevention and treatment of obesity, ageing

and cancer within s-NCM new knowledge based model of living cells, which are

existed as "central cognitive - knowledge bridge" between theoretical, diagnostic and

treatment aspects of Traditional and Modern medicine.

Results of investigation:

By using comparative analytical methods, we demonstrated in 1990 for the first time

and eventually confirmed that whole body's membrane - redoxy potentials 3 state line

system, which existed in the three basic states as:

1. Fluid - alpha state of membrane structures with high level of oxidation potential

with high level of heat energy formation, with high level of proton leak, proton




38

conductance, with middle intensity of high energy phosphate - ATP generation, of

high energy electrons - NADPH generation.

2. Solid betta - state of membrane structures with high level of reduction potential

with middle level of heat energy formation, with low level of proton leak, proton

conductance, with high intensity of high energy phosphate - ATP generation, of high

energy electrons - NADPH generation.

3. Intermediate gamma state of membrane structures with low level of oxidation -

reduction potential with low level of proton gradient generation, low level of heat

energy formation, with low intensity of high energy phosphate - ATP generation, with

low intensity of high energy electrons - NADPH generation could play the role of such

a biological substance, relating to theory of 5 element and theory of rlung, mkhris,

badgan.

A. Fluid - alpha state of membrane structures with high level of oxidation potential

with high level of heat energy formation, with high level of proton leak, proton

conductance, with middle intensity of high energy phosphate - ATP generation, of

high energy electrons - NADPH generation, it's hot, hot oil, acute external functional

properties corresponds to the fire element related - sun like mkhris abstract notion.

B. Solid betta - state of membrane structures with high level of reduction potentia l

with high middle level of heat energy formation, with low level of proton leak, proton

conductance, with high intensity of high energy phosphate - ATP generation, of high

energy electrons - NADPH generation, it's cool, cold oil, heavy, stupid external

functional properties summarized under the water - earth elements related - moon

like badgan abstract notion. of badgan.

C. Intermediate gamma state of membrane structures with low level of oxidation –


energy formation, with low intensity of high energy phosphate - ATP generation, of

high energy electrons - NADPH generation and heat energy, its mobile, unoilly, light

external functional properties is symbolized under the wind element related - wind

like rlung abstract notion.

Scientic essence of our new suggestion lies in discovering "those material subjects"

and revealing this secrets of theory of Rlung - Mkhris - Badgan, why under only

similar thermin of rlung - Mkhris - Badgan in Oriental and Mongolian traditional

medicine had expressed more different things, including the whole organism's

regulatory function, seasonal, age and daily changes, specific appearance of R.M.B

in individuals and five sold organs, signs of disease, causes of disease, provocation's

and dietary factors.

Abovementioned discovery summarized within s-NCM new knowledge was the

scientific - methodological basis to laid foundation of new integrated triple medical

system - NCM medicine.




39

What is specificity of new integrated triple medical system-NCM which at first

developed by us:

a. Consisted of of traditional (X and G - knowledge based) and modern medical

system (S-knowledge based) integrated through s-NCM new knowledge.

b. Decided all diagnostic and treatment problems using triple approaches as tradinal

(X and G-knowledge based) and modern medical system (S-knowledge based)

integrated through s-NCM new knowledge.

What is specificity of membrane - redoxy potentials three state line systems,

which at first revealed by us:

Consisted of H,e donators as foods and H,e acceptors as oxygens

a. Ensured normal flow of protons and electrons from donators to acceptors with

generation of high energy phosphate-ATP, high energy electrons NADPH and heat

energy

b. Functioned with using a glycolysis, Krebs cycle, oxidative deamination and betta

oxidation reaction to generate normal flow of protons and electrons.

c. Provided the normal maintainance of living processes.

d. Existed in three interconvertible states:

- fluid alpha state, consisting of mainly unsaturated fatty acids, conditioning a high

levels of oxy potentials and with high levels of proton, electrons conductance and

high levels of heat energy release, middle degree of energy accumulation and middle

degree of high energy phosphate - ATP, high energy electrons NADPH, with middle

ratio of donators : accceptors.

- solid betta state, consisting of mainly saturated fatty acids, conditioning a high

levels of red potentials and with slow levels of proton, electrons conductance and

low levels of heat energy release, high degree of energy accumulation and high

degree of high energy phosphate - ATP, high energy electrons NADPH, with

increased ratio of donators : acceptors – gamma state, consisting of decreased

contents of saturated-unsaturated fatty acids, conditioning a decreased levels of

redoxy potentials and with slow levels of proton, electrons conductance and low

levels of heat energy release and energy accumulation and low degree of high

energy phosphate - ATP, high energy electrons NADPH, with decreased contents of

donators: accceptors, increased significance of proton, electrons prior to generation

of proton gradients, prevailed slip mecchanism.

D. The specificity of abstract theory of Rlung, Mkhris, Badgan (vata, kapha,

pitta, yun, yan) would be characterized by a following patterns because of

nonexistence of human species as “Homo sapiens plus rlung, mkhris,

badgan”, “Homo sapiens plus vata, kapha, pitta”, “Homo sapiens plus yan,

yin” as if containing the 14 trillion living rlung, mkhris, badgan, yin, yan along

with 14 trillion living cells only postulated by Traditional medicine doctors, all




40

their diagnostic and treatment methods based in this form of human specie,

but categorically resisted, refused by NCM medicine :

a. It is include a general pattern of maintainance of normal living processes with

participation of membrane - redoxy potentials three state line systems, ensuring

normal flow of protons and electrons from donators to acceptors with generation of

high energy phosphate - ATP, high energy electrons NADPH and heat energy

through carbohydrate glycolysis, Krebs cycle, oxidative deamination of aminoacids

and betta oxidation of fatty acids .

b. It is include a general pattern of normal functioning of living system with

participation of 5 membrane structures - 5 function systems, ensuring normal genetic

- cell devision, information - response, biosynthetical, bioenergetical,

biotransformation functions by using of high energy phosphate - ATP, high energy

electrons NADPH and heat energy, generated in membrane - redoxy potentials three

state line systems.

E. The coincidence between abstract theory of Rlung, Mkhris, Badgan and

membrane - redoxy potentials three state line systems in the first compartment,

which at first revealed by us would be characterized by a following patterns because

of nonexistence of human species as ―Homo sapiens plus rlung, mkhris, badgan‖,

―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan, yin‖ as if containing

the 14 trillion living rlung, mkhris, badgan, yin, yan along with 14 trillion living cells

only postulated by Traditional medicine doctors, all their diagnostic and treatment

methods based in this form of human specie, but categorically resisted, refused by

NCM medicine.

a. Fluid alpha states, consisting of unsaturated fatty acids with high levels of oxy

potentials and with high levels of proton, electrons conductance and high levels heat

energy release, middle degree of energy accumulation and middle degree of high

energy phosphate-ATP, high energy electrons NADPH, with middle ratio of donators:

accceptors are associated with abstract theory of Mkhris (pitta), which is


b. Solid betta state, consisting of mainly saturated fatty acids, conditioning a

high levels of red potentials and with slow levels of proton, electrons conductance

and low levels of heat energy release, high degree of energy accumulation and high

degree of high energy phosphate-ATP, high energy electrons NADPH, with

increased ratio of donators : accceptors are associated with abstract theory of

Badgan (kapha), which is distinguished by cool, cold oil, stupid external

characteristics.

c. Gamma state, consisting of decreased contents of saturated - unsaturated

fatty acids, conditioning a decreased levels of redoxy potentials and with slow

levels of proton, electrons conductance and low levels of heat energy release and

energy accumulation and low degree of high energy phosphate - ATP, high energy

electrons NADPH, with decreased contents of donators: accceptors, increased




41

significance of proton, electrons prior to generation of proton gradients, prevailed slip

mecchanism are associated with abstract theory of rlung (vata), which is

distinguished by light, mobile, nonoil, cool external characteristics.

The scientific - methodological basis of newly coded medicine (NCM) is

characterized by following novelty:

1. In the result of proposing the new enriched definition of living cells within s-NCM

new knowledge, which clarified that main key regulating mechanism of living cells are

a three states of membrane - redoxy potentials, providing a normal flow of protons

and electrons, by us has been established that between the quantative proportion of

abstractized first compartment related rlung, mkhris, badgan code and some

parameters of cell membrane redoxy potentials, located intercellularly in first

compartment are existed the more strong correlation as: the elevated quantative

proportion of abstractized by mkhris diagnostic parameters is associated with high

oxy potentials (first compartment), the increased quantative proportion of

abstractized by rlung diagnostic parameters is accompanied with slow redoxy

potentials (first compartnent), the elevated quantative proportion of abstractized by

badgan diagnostic parameters is associated with high red potentials (first

compartnent) in the healthy persons

2. It has been revealed that between the quantative proportion of of abstractized

second compartment related rlung, mkhris, badgan (vata, kapha, pitta, yun, yan)

code and some parameters of of cell membrane redoxy potentials, located

extracellularly in second compartment are existed the more strong correlation as:

a. the elevated quantative proportion of abstractized by rlung code, located outside

of cells is associated with low redoxy potentials (second compartment), expressed as

a low internal and external adipocyte tissues, Rid formula, urine and serum oxidase

enzyme activity, urine ph, resistance of membrane structures, high concentration of

deprotonizid products in the membrane structures, low level of serum cholesterol,

triglycerids in the Healthy persons. An all above mentioned code correlation as

―abstract thermins as rlung, mkhris, badgan - a three states of membrane- redoxy

potentials of living cells‖ serves the main scientifico-methodological basis of Newly

Coded Medicine (NCM), which originated in the integration of traditiona l and recent

medicine, but principally distinguished from traditional and recent medicine, taken

separately.




42

Picture № 1

Betta state

ABSTRACTION IN THE FORM OF APPEARANCE OF THEORY OF RLUNG, MKHRIS, BADGAN (YANG-YIN)

“FIRE” ELEMENT “RLUNG” ELEMENT “WATER, EARTH” ELEMENT

Acute, hot

characreistics

Unoil characreistics Cold, heavy characteristics

The intensification of the thermogenesis and activation of whole

organism’s functional level

The prevalence of

gamma state of MS with

low redoxy potentials

The relatively limitation of the thermogenesis, intensification of energy accumulation, decrease of

functional activity of human body

Whole organism’s level

Organ’s level

Tissue’s level

Alpha state

witswioxy

potentials

Gamma

state The basic three states of membrane – redoxy potential 3 state system




43

New integrated triple medical system (NCM) Picture № 2

A.The specificity of new cognitive steps may be describe as: Really existed

substance - revealing of external patterns - intelectually transformation of

these to the first variant of abstraction as 5 elements, transformation of these

to the second variant of abstraction as Rlung, Mkhris, Badgan because of

nonexistence of human species as “Homo sapiens plus rlung, mkhris,

badgan”, “Homo sapiens plus vata, kapha, pitta”, “Homo sapiens plus yan,

yin” as if containing the 14 trillion living rlung, mkhris, badgan, yin, yan along

with 14 trillion living cells only postulated by Traditional medicine doctors , all

their diagnostic and treatment methods based in this form of human specie,

but categorically resisted, refused by NCM medicine:

According to the new cognitive steps, formulated by us as: ―Really existed substance

(- revealing of 20 external patterns - abstractized transformation of these to the first

variant of abstraction as 5 elements (A-1), abstractized transformation of these to the

second variant of abstraction as Rlung, Mkhris, Badgan (vata, kapha, pitta, yun,

yan) - (A-2) ―when within membrane - redoxy potentials 3 state line system, that

provide the normal existence of all cells by ensuring normal flow of electrons,

protons with generating the proton gradient have been prevailed:

1. The fluid alpha state of membrane structures with high oxidation potential, high

level of proton conductance and high level of proton leak play role of Really existed

substance (S), because of this among 20 external patterns (EP) prevailed 7 patterns

as hot, hot oil, acute et all, which at first were abstractized by hot - fire element

among 5 elements (A-1), at second were abstractized by fire element related moon

like mkhris (A-2).

2. The solid betta state of membrane structures with high reduction potential, middle

level of proton conductance and middle level of proton leak play role of Really

existed substance (S), because of this among 20 external patterns (EP) dominated 7

patterns as cold, cold oil, heavy, stupid et all, which at first were abstractized by cold-

heavy earth, water elements among 5 elements (A-1), at second were abstractized

by earth, water element related moon like badgan (A-2).




44


level of proton conductance and middle level of proton leak play role of Really existed

substance (S), because of this among 20 external patterns (EP) dominated 7

patterns as cold, cold oil, heavy, stupid et all, which at first were abstractized by light,

mobole wind element among 5 elements (A-1), at second were abstractized by wind

element related rlung (A-2).

B. What is specificity of s-NCM new knowledge, which at first proposed by us:

a. Described a living cells and living organism as complex system, consisting of 4

basic compartments.

b.1. First compartment, named as membrane-redoxy potentials three state line

systems, ensuring normal flow of protons and electrons from donators to acceptors

with generation of high energy phosphate-ATP, high energy electrons NADPH and

heat energy through glycolysis reaction, Krebs cycle, oxidative deamination and betta

oxidation reactions.

b. 2. Fourth compartment, named as 5 membrane structures-5 function systems,

ensuring normal genetic - cell division, information - response, biosynthetical,

bioenergetical, biotransformation functions by using of high energy phosphate - ATP,

high energy electrons NADPH and heat energy, generated in membrane - redoxy

potentials three state line systems.

c. Second compartment consists of serum and extracellular system, where donators,

acceptors and some metabolites formed in the result of functioning of 5 of membrane

structures-5 function systems, including biosynthetic, bioenergy, biotransformation

functions, also products of AO-SPOL system temporarely existed.

d. Third compartment consists visceral and under skin fatty acids, where donators,

acceptors, products of AO-SPOL system are existed relatively constant.

Developing by us the new knowledge as s-NCM new knowledge gives the possibility

a integration of traditional and modern medicicne through it.

C. What is specificity of membrane - redoxy potentials three state line

systems, which at first revealed by us:

Consisted of H,e donators as foods and H,e acceptors as oxygens

a. Ensured normal flow of protons and electrons from donators to acceptors with

generation of high energy phosphate-ATP, high energy electrons NADPH and heat

energy

b. Functioned with using a glycolysis, Krebs cycle, oxidative deamination and betta

oxidation reaction to generate normal flow of protons and electrons.

c.Provided the normal maintainance of living processes.

d. Existed in three interconvertible states:

- fluid alpha state, consisting of mainly unsaturated fatty acids, conditioning a high

levels of oxy potentials and with high levels of proton, electrons conductance and




45

high levels of heat energy release, middle degree of energy accumulation and middle

degree of high energy phosphate-ATP, high energy electrons NADPH, with middle

ratio of donators : accceptors.

- solid betta state, consisting of mainly saturated fatty acids, conditioning a high

levels of red potentials and with slow levels of proton, electrons conductance and

low levels of heat energy release, high degree of energy accumulation and high

degree of high energy phosphate - ATP, high energy electrons NADPH, with

increased ratio of donators : acceptors - gamma state, consisting of decreased

contents of saturated-unsaturated fatty acids, conditioning a decreased levels of

redoxy potentials and with slow levels of proton, electrons conductance and low

levels of heat energy release and energy accumulation and low degree of high

energy phosphate - ATP, high energy electrons NADPH, with decreased contents of

donators: accceptors, increased significance of proton, electrons prior to generation

of proton gradients, prevailed slip mecchanism.

E. The coincidence between abstract theory of Rlung, Mkhris, Badgan and

membrane - redoxy potentials three state line systems in the first compartment

may be characterized by following specity with consideration that there are not

existed a human species as “Homo sapiens plus rlung, mkhris, badgan”,

“Homo sapiens plus vata, kapha, pitta”, “Homo sapiens plus yan, yin” as if

containing the 14 trillion living rlung, mkhris, badgan, yin, yan along with 14

trillion living cells only postulated by Traditional medicine doctors, all their

diagnostic and treatment methods based in this form of human specie, but

categorically resisted, refused by NCM medicine:

a. Fluid alpha states, consisting of unsaturated fatty acids with high levels of oxy

potentials and with high levels of proton, electrons conductance and high levels heat

energy release, middle degree of energy accumulation and middle degree of high

energy phosphate - ATP, high energy electrons NADPH, with middle ratio of

donators: accceptors are associated with abstract theory of Mkhris, which is


b. Solid betta state, consisting of mainly saturated fatty acids, conditioning a

high levels of red potentials and with slow levels of proton, electrons conductance

and low levels of heat energy release, high degree of energy accumulation and high

degree of high energy phosphate-ATP, high energy electrons NADPH, with

increased ratio of donators : accceptors are associated with abstract theory of

Badgan, which is distinguished by cool, cold oil, stupid external characteristics.

c. Gamma state, consisting of decreased contents of saturated - unsaturated

fatty acids, conditioning a decreased levels of redoxy potentials and with slow

levels of proton, electrons conductance and low levels of heat energy release and

energy accumulation and low degree of high energy phosphate - ATP, high energy

electrons NADPH, with decreased contents of donators: accceptors, increased




46

significance of proton, electrons prior to generation of proton gradients, prevailed slip

mecchanism are associated with abstract theory of rlung, which is distinguished by

light, mobile, nonoil, cool external characteristics.

I. The coincidence between abstract theory of Rlung, Mkhris, Badgan and

Fourth compartments parameters may be characterized by following specity

with consideration that there are not existed a human species as “Homo

sapiens plus rlung, mkhris, badgan”, “Homo sapiens plus vata, kapha, pitta”,

“Homo sapiens plus yan, yin” as if containing the 14 trillion living rlung,


Traditional medicine doctors, all their diagnostic and treatment methods based

in this form of human specie, but categorically resisted, refused by NCM

medicine:

a. Change of fourth compartment parameters, named as 5 membrane structures-5

function systems, ensuring normal genetic-cell division, information-response,

biosynthetical, bioenergetical, biotransformation functions by using of high energy

phosphate - ATP, high energy electrons NADPH and heat energy, generated in

membrane - redoxy potentials three state line systems in the form of decrease of

synthetic, bioenergy, biotransformation functions and of unregulated disturbance of

information-response functions are coded by abstract Rlung code in the Tibetian


b. Change of fourth compartment parameters, named as 5 membrane structures - 5




membrane - redoxy potentials three state line systems in the form of unregulated

intensification of information-response functions are coded by abstract Mkhris code.

c. Change of fourth compartment parameters, named as 5 membrane structures-5



phosphate-ATP, high energy electrons NADPH and heat energy, generated in

membrane-redoxy potentials three state line systems in the form of slowing of

information-response functions are coded by abstract Mkhris code in the Tibetian


The coincidence between abstract theory of Rlung, Mkhris, Badgan and second

compartments parameters may be characterized by following specity with

consideration that there are not existed a human species as “Homo sapiens

plus rlung, mkhris, badgan”, “Homo sapiens plus vata, kapha, pitta”, “Homo

sapiens plus yan, yin” as if containing the 14 trillion living rlung, mkhris,

badgan, yin, yan along with 14 trillion living cells only postulated by Traditional

medicine doctors, all their diagnostic and treatment methods based in this

form of human specie, but categorically resisted, refused by NCM medicine:




47

a. Change of second compartment parameters, consisting of serum and extracellular

system, where donators, acceptors and some metabolites formed in the result of

functioning of 5 membrane structures - 5 function systems, ensuring normal genetic -

cell division, information - response, biosynthetical, bioenergetical, biotransformation

functions in the form of decrease of contents of donators, acceptors and some

metabolites formed in the result of functioning of 5 of membrane structures-5

function systems, including synthetic, bioenergy, biotransformation functions are

coded by abstract Rlung code in the Tibetian Mongolian Traditional medicine.

b. Change of second compartment parameters consisting of serum and extracellular


functioning of 5 membrane structures-5 function systems, ensuring normal genetic-

cell division, information-response, biosynthetical, bioenergetical, biotransformation

functions in the form of increase of contents of donators, decrease of acceptors and

increase of AO - decrease of SPOL system are coded by abstract Badgan code in


c. Change of second compartment parameters consisting of serum and extracellular


functioning of 5 membrane structures-5 function systems, ensuring normal genetic -

cell division, information - response, biosynthetical, bioenergetical, biotransformation

functions in the form of decrease of contents of donators, increase of acceptors and

decrease of AO - increase of SPOL system are coded by abstract Badgan code in


The coincidence between abstract theory of Rlung, Mkhris, Badgan and Third

compartments parameters may be characterized by following specity with

consideration that there are not existed a human species as “Homo sapiens

plus rlung, mkhris, badgan”, “Homo sapiens plus vata, kapha, pitta”, “Homo

sapiens plus yan, yin” as if containing the 14 trillion living rlung, mkhris,

badgan, yin, yan along with 14 trillion living cells only postulated by Traditional

medicine doctors, all their diagnostic and treatment methods based in this

form of human specie, but categorically resisted, refused by NCM medicine:

a. Change of Third compartment parameters in the form of decrease of visceral and

external under skin fatty acids, also donators, acceptors are coded by abstract Rlung

code in the Tibetian Mongolian Traditional medicine.

b. Change of Third compartment parameters in the form of increase of saturated

class of visceral and external under skin fatty acids, also increase of donators,

decrease of acceptors are coded by abstract Badgan code in the Tibetian Mongolian


c. Change of Third compartment parameters in the form of increase of unsaturated

class of visceral and external under skin fatty acids, also decrease of donators,




48

increase of acceptors are coded by abstract Mkhris code in the Tibetian Mongolian


In such way we should recognize that appearing of abstract theory of Rlung, Mkhris,

Badgan in Tradititional medicine 3 thousand years ago - follow from the functioning

of membrane - redoxy potentials three state line systems in the first compartment

with close relationship with fourth and second, third compartments in human body

M. What is life process according to new integrated triple medical system -

NCM which at first developed by us:

Life is specific process, occurred in living cells, appeared as normal conductance of

electrons and protons with participation of electrons and protons donators (food

intake) - acceptors (breathihg-oxygens), which needs membrane - redoxy potentials

three state line systems, which leads to formation of ATP, NADPH, heat energy,

which creates the basis to formation of action potential - nervous impulse generation

- propagation and cell division, bioenergetical, biotransformation functions.

N. What is lifekeeping rlung according to new integrated triple medical system

- NCM which at first developed by us:

Life keeping rlung is specific notion of theory of Traditional medicine formed in result

of imagination of ancient philosophers indicating a how human body works and

regulate, ensure the normal conductance of electrons and protons with participation

of electrons and protons donators (food intake) - acceptors (breathihg - oxygens),

which needs membrane - redoxy potentials three state line systems inside of living

cells, which leads to formation of ATP, NADPH, heat energy, which would create the

basis to formation of action potential - nervous impulse generation - propogation and

cell division, bioenergetical, biotransformation functions.

O. New definition of living cells according to new integrated triple medical

system - NCM which at first developed by us:

Living cells are functional - structural unit of human body, consisting from membrane

- redoxy potentials three state line systems, which ensure constant flow of electrons

and protons between Donators and Acceptors with producing high energy phosphate

- ATP, high energy electrons - NADPH, heat energy, thereby able to maintain normal

occuring of information - response function in plasmic membrane, genetic - cell

division function in nucleus membrane, biotransformation function in microsomal

membrane and biosynthetic - rebiosynthetic function in ribosome - microsomal and

lisosomo – pereoxisamal membrane, bioenergetical function in mitochondrial

membrane, beside all their important molecules have general “nucleoside +

phosphate” structures.




49

U. What is x, g, S, s-NCM stage of developing of medical thinking of humanity

according to new integrated triple medical system - NCM which at first

developed by us:

In the framework of NCM medicine we also untroduce the therminology as x, g, S, s-

NCM period time - stage of developing of medical thinking of humanity, which made

of chronology of appearing a more important time interval of developing and

foundation of traditional and modern, also NCM medicine much clearer than it have

been before.

G-period is time of appearing of theory of 20 external patterns of Traditional

medicine, X- period is time of appearing of theory of 5 elements and abstract theory

of Rlung, Mkhris, Badgan of Traditional medicine, when yet not formed knowledge

as s - NCM knowledge, also Modern medical knowledge as S.

S-period is time of appearing and developing of Modern medicine, which are not

used knowledge as X and G knowledge.

S-NCM period is time of developing and establishing of NCM medicine, which used

Tradiditional medical knowledge as X, G, Modern medical knowledge as S and new

s - NCM knowledge all together, through it have been integrated all medical

knowledge, formed during all time of developing of medical systems.

U. What is definition of Traditional medicine.

Owing to foundation of NCM medicine became clear that such very important

regulations as gene in the one side, Rlung, Mkhris, Badgan in the another side, also

such scientific knowledge as genetics and Traditional medicine existed in the one

unseparable cognitive chains, consisting of whole 6 steps, started by gene regulation

in the 1 step - ended by Rlung, Mkhris, Badgan coding in the therminal sixth step

because of nonexistence human species as ―Homo sapiens plus rlung, mkhris,


containing the 14 trillion living rlung, mkhris, badgan, yin, yan along with 14 trillion




Traditional medicine is medical system originated by abstractizing and

transforming a different external patterns, appeared in outside of human body

because of variety of enzyme - substrates relationship in the living cell level,

manufactured under ―information - instruction - signalling ―functions of corresponding

genes, in the first case by 5 elements as fire, water, earth, wind, in the second

case by moon like badgan coding, sun like Mkhris coding, wind like Rlung coding.




50

Picture № 3

In the frame work of new conception of the "rlung, Mkhris, Badgan - membrane

structure - redoxy potentials 3 states "we have managed to explain the membrane -

redoxy potential based mechanism of theory of TMTM in relation to taste and

power, property of old medicaments and pulse diagnostic methods.

According to the new cognitive steps, formulated by us as: ―Really existed substance

(S) - revealing of 20 external patterns (EP) - intelectually transformation of these to

the first variant of abstraction as 5 elements (A-1), transformation of these to the

second variant of abstraction as Rlung, Mkhris, Badgan(A-2) ―when within membrane

- redoxy potentials 3 state line system, that provided the normal existence of all

cells by ensuring normal flow of electrons, protons with generating the proton

gradient have been prevailed :

1. The fluid alpha state of membrane structures with high oxidation potential, high

level of proton conductance and high level of proton leak play role of Really existed

substance (S), because of this among 20 external patterns (EP) prevailed 7 patterns

as hot, hot oil, acute et all, which at first were abstractized by fire element among 5

elements (A-1), at second were abstractized by mkhris (A-2).


level of proton conductance and middle level of proton leak play role of Really

existed substance (S), because of this among 20 external patterns (EP) dominated 7

patterns as cold, cold oil, heavy, stupid et all, which at first were abstractized by

earth, water elements among 5 elements (A-1), at second were abstractized by

badgan (A-2).


level of proton conductance and middle level of proton leak play role of Really existed

The theory

“rlung, Mkhris, Badgan”

A

General

characteristics

Solid organs

Season

Age

Constitution type of

individuals

Dietary factors

Medicaments

B

The all recent informations, regarding to regulation function of membrane –redoxy potential 3 state regulation of human body




51

substance (S), because of this among 20 external patterns (EP) dominated 7

patterns as cold, cold oil, heavy, stupid et all, which at first were abstractized by

wind element among 5 elements (A-1), at second were abstractized by rlung (A-2).

Besides, the new conception "rlung, Mkhris, Badgan - membrane - redoxy

potentials 3 state line system "allows the possibility to explain following general

notions of TMTM in accordance to suggested by us new conception:

1. General characteristics of rlung, Mkhris, Badgan as hot, cold, acute, stupid, motile,

light

2. Division of Human Constitution specificity to Mkhris. rlung. Badgan.

3. Classification of five solid organs in relation to rlung. Mkhris. Badgan

4. Classification of Diet factors in relation to rlung. Mkhris. Badgan

5. Classification of Medicines in relation to rlung. Mkhris. Badgan (increasing and

decreasing)

6. Seasonal changes of functional activity of Solid organs.




52

MEMBRANE - REDOXY POTENTIAL 3 STATE MECHANISM OF THEORY OF

TRADITIONAL MEDICINE ABOUT INTERRELATIONSHIP AND

INTEROPPOSITION OF RLUNG, MKHRIS, BADGAN

Picture № 3.1

The intermediate gamma state of membrane structure with low redoxy potentials

The increase

of induction

of the

action

potential

Decrease of

generation

of ATP,

NADPH,

heat energy

from proton

gradients

The

intensificatio

n of nerve

impulse

conduction

(conductivit

y)

The decrease

of ATP,

protein,

NADPH,

lipoproteid

synthesis

The low level

of thermo

genesis

Mobile Light Thin (narrow) Rough Cool




53

l. General characteristics of rlung, Mkhris, Badgan, their unterrelation,

interopposition and property of membrane-redoxy potentials 3 state line

system.

The reason why the general characteristics of rlung, Mkhris, Badgan should be

explained in the level of membrane - redoxy potential 3 state line dependent systems

as 4 compartments and 10 functional systems comprising all 14 trillion cells of human





Traditional medicine doctors, all their diagnostic and treatment methods based in this

form of human specie, but categorically resisted, refused by NCM medicine.

According to theory of Traditional medicine the general characteristics of Mkhris,

Badgan, Rlung are as follows: "... Mkhris is characteristically hot, oily, acrid (acute-),

light... Badgan is characteristically cool, oily, stupid, heavy ...Rlung is

characteristically motile, unoilly, rough, light..."

More quantity of unsaturated fatty acids (UFA) as main part of fluid – alpha state of

membrane structures with high level of oxidation potential with high level of heat

energy formation, middle intensity of high energy phosphate - ATP generation, of

high energy electrons - NADPH generation have T°-smelting + 15°- + 18°C i.e

possessed the most "hot" property and easily undergoes to structural changes,

coupling with formation of "thermogenic, protonophore phore" (Ya.Musil 1984) which

are accompanied by dispersion of many quantity "heat energy" (V.P.Skulacher 1972).

As regards to "acute" characteristic of Mkhris may be connected with very high

reactivity of UFA (oc-state) of membrane structures (Yu.A.Vladimirov et all 1972).

Addition of "one unsaturated bind" leads to 11-fold increase of "coefficient of

reactivity", while 4-6 unsaturated binds resulted to 1739-3478 fold increase of

reactivity (A.N.Detsina et all 1990, V.N.Ushkalova 1986). In close connection with

this in solid organs, where predominated a-state of membrane-redoxy potentials 3

state line system extent of damage and disturbances of membrane structures

following the onset of disease proceeds in more intensive range (Ya.A.Vladimirov et

all 1972) while (3-state of MS (badgan) showed slow reactivity (Ya.M.lopukhin et all

1983), which coincided with "stupid" characteristic of "Badgan".

In such way in framework of the new conception we are explaining that "hot", "acute",

"oily" characteristics of "Mkhris" has connected with "thermogenic", "protonophore".

"activatining" action of a-state (unsaturated fatty acids) of MS




54

MEMBRANE – REDOXY POTENTIAL 3 STATE MECHANISM OF

APPEARANCE OF THEORY OF TRADITIONAL MEDICINE ABOUT

INTERRELATIONSHIP AND INTEROPPOSITION OF RLUNG, MKHRIS,

BADGAN

Picture № 4

The gamma state of membrane structure with low redoxy potentials

The increase of

induction of

the action

potential

Decrease of

generation of

ATP,

NADPH,

heat energy

from proton

gradients

The

intensificatio

n of nerve

impulse

conduction

(conductivity)

The decrease of

ATP, protein,

NADPH,

lipoproteid

synthesis

The low level of

thermo genesis

Mobile Light Thin (narrow) Rough Cool

The fluid alpha state of Membrane structure with high oxy potentials

Theprevalence of

unsaturated fatty

acids in MS

(cisconfiguration)

which easily

subjected to

melting

The high

thermogenic

activity by

uncoupling

mechanism

O/P

The

intensificatio

n of activity

of membrane

binding

enzymes and

receptors

The increase of activity of

adrenoreceptors and

reception activity of action of

Medicaments hormones,

external factors

Hot-oily Hot Light Acute

While "cold", "heavy", "stupid" characteristics of "Badgan" has coincided with "energy

accumulating", heat limiting, "stabilizing" effects of (betta - state - saturated fatty

The solid betta state of membrane structure with high red potentials

The prevalence

of saturated

fatty acids in

MS (trans-

configuration)

, which easily

subjected to

freezing

The limitation of

thermo

genesis by

O/P

mechanism

The decrease

of activity of

membrane

binding

enzymes,

receptors

and the

increase of

ATP-

synthesis

The decrease of

reception

activity of

action of

Medicament

s, hormones

external

factors

The increase of

activity of

cholinoreceptors

and the

decrease of

cholinesterase

activity

Cool-oily Cold Heavy, strong Stupid Mucous (mucus)




55

acids) of MS i.e solid betta - state of membrane structures with high level of reduction

potential with high middle level of heat energy formation, high intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation,

containing more quantity of cholesterol, and saturated fatty acids (SFA), which

according to our new suggestion conditioned the abstraction notion "Badgan" also

possessed "cold" property, having T°-of smelting + 53 - + 69°C (Ua.Kagava 1985,

U.Strier 1984).

Apart from this solid betta - state of membrane structures with high level of reduction

potential with high middle level of heat energy formation, high intensity of high

energy phosphate - ATP generation, of high energy electrons - NADPH generation

(cholesterol, and SFA) possessed more resistence to action of various

"protonophore" factors (Yu.M.Lopukhin et all 1983, G.I.Klebanov et all 1986), which is

conditioned less thermogenic activity (V.P.Skulachev 1971) and resulted to limitation

of thermogenesis.

Also, "motile", "light" characteristics of rlung are due to nerve impulse generating and

impulse conducting activity of intermediate gamma state of membrane structures

with low level of oxidation - reduction potential of excitable membranes (excitable

cells), which for their normal functioning are required a high level of proton gradient

generation, high level of intensity of high energy phosphate - ATP generation, high

level of high energy electrons - NADPH generation, but the intermediate gamma

state of membrane structures with low level of oxidation - reduction potential can

not provide this in the sufficient level.

In case of shortage of proton gradient generation and deficiency of high energy

phosphate - ATP generation, high level of high energy electrons - NADPH

generation, which more easily provocated when dominated the intermediate gamma

state of membrane structures with low level of oxidation - reduction potential are

resulted to appearance of "motile", "light" characteristics, coded by abstract rlung

thermin.

At normal condition, basic 3 states of MS existed in mutual transition and mutual

oppression which connected with theory of TMTM about interrelation - interposition

property of rlung, Mkhris, Badgan.

Theory of Mongolian traditional medicine considered that ". . . cool character of

Badgan decreases hot character of Mkhris . . , Hot - oilness of Mkhris prevents

excessively increase of cold (cool) - oilness of Badgan i.e Mkhris and Badgan existed

in interrelations and interopposition ... ".




56

THE BASIC PERIOD OF APPEARENCE OF THE THEORY OF FIVE

ELEMENTS AND THEORY OF ―RLUNG, MKHRIS, BADGAN‖, ―YANG-YIN‖

Picture № 5

By our opinion, above mentioned theoretical expression of Traditional Medicine had

been appeared in the result of reflection "transitional processes", which take place as

follows:

1. The intermediate gamma state of membrane structures with low level of oxidation

- reduction potential with low level of proton gradient generation, low level of heat

energy formation, low intensity of high energy phosphate - ATP generation, low

intensity of of high energy electrons - NADPH generation supressed the excess

prevalence of solid betta - state of membrane structures with high level of reduction

potential with middle level of heat energy formation, high intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation.

2. The fluid - alpha state of membrane structures with high level of oxidation

potential with high level of heat energy formation, middle intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation

supressed the excess prevalence of solid betta - state of membrane structures with

high level of reduction potential with middle level of heat energy formation, high

intensity of high energy phosphate - ATP generation, of high energy electrons -

NADPH generation‖.

THE

SUBSTA

NCE

EXTERN

AL

SIGNS

ABSTRACTI

ON

The three states of

MS with 3 state of

redoxypotentials

Substance

Fire, water, earth,

rlung, space,

wood, iron

elements

The step of cognition by the

direct sensation

The step of abstract

cognition

Hot

Acute

Heav

y

Light

Fluid

Motile

Stupid

Cold

Hot

Acute

Fluid

Cold

Heavy

Stupid

UnoillyL

ig

Motile

Fire

element

Water

element

Earth

element

Rlung

element

Mkhris

(yang)

Badgan

(yin)

Rlung




57

3. The solid betta - state of membrane structures with high level of reduction


phosphate - ATP generation, of high energy electrons - NADPH generation‖

supressed the excess prevalence of the fluid - alpha state of membrane structures

with high level of oxidation potential with high level of heat energy formation, middle

intensity of high energy phosphate - ATP generation, of high energy electrons -

NADPH generation.

4. The intermediate gamma state of membrane structures with low level of oxidation

- reduction potential with low level of proton gradient generation, low level of heat

energy formation, low intensity of high energy phosphate - ATP generation, low

intensity of of high energy electrons - NADPH generation supressed the excess

prevalence of the fluid - alpha state of membrane structures with high level of

oxidation potential with high level of heat energy formation, middle intensity of high

energy phosphate - ATP generation, of high energy electrons - NADPH generation

5. The fluid - alpha state of membrane structures with high level of oxidation

potential with high level of heat energy formation, middle intensity of high energy

phosphate - ATP generation, of high energy electrons - NADPH generation

supressed the excess prevalence of the intermediate gamma state of membrane

structures with low level of oxidation - reduction potential with low level of proton

gradient generation, low level of heat energy formation, low intensity of high energy

phosphate - ATP generation, low intensity of of high energy electrons - NADPH

generation

6. The solid betta - state of membrane structures with high level of reduction


phosphate - ATP generation, of high energy electrons - NADPH generation‖

supressed the excess prevalence of the intermediate gamma state of membrane


gradient generation, low level of heat energy formation, low intensity of high energy


generation

Besides this, the solid betta - state of membrane structures with high level of

reduction potential with middle level of heat energy formation, high intensity of high

energy phosphate - ATP generation, of high energy electrons - NADPH generation‖

served the role of precondition of normal existence and normal formation and

reformation of the intermediate gamma state of membrane structures with low level

of oxidation - reduction potential with low level of proton gradient generation, low

level of heat energy formation, low intensity of high energy phosphate - ATP

generation, low intensity of of high energy electrons - NADPH generation, meanwhile

the fluid - alpha state of membrane structures with high level of oxidation potential

with high level of heat energy formation, middle intensity of high energy phosphate -

ATP generation, of high energy electrons - NADPH generation served the role of




58

precondition of normal existence and normal formation and reformation of the

intermediate gamma state of membrane structures with low level of oxidation -


energy formation, low intensity of high energy electrons - NADPH generation‖.

The fluid - alpha state of membrane structures with high level of oxidation potential

with high level of heat energy formation, middle intensity of high energy phosphate -

ATP generation, of high energy electrons - NADPH generation served the role of

precondition of normal existence and normal formation and reformation of the solid

betta - state of membrane structures with high level of reduction potential with

middle level of heat energy formation, high intensity of high energy phosphate - ATP

generation, of high energy electrons - NADPH generation‖ i.e in favour of this

suggestion recently has been established that unsaturated fatty acids of alpha state

(fluidity) of membrane structures prevents excessive increase of saturated fatty acids

of betta state of MS (solid), while betta state of MS (solid) decreases and maintaines

the normal alpha - state of MS /L.Strier 1985, E.Kreps 1981, Ya,Kagava 1985/

(Picture N 4)

One simple example of such processes is addition of one unsaturated bind of a -

state of MS to p - state of MS accompanied with decrease of T° of smelting from +

39.5-to + 14°C, which may be serve as one of the proofs of Traditional medicine's

conception: ". . . hot of Mkhris decreases cold of Badgan. . . " (Picture N 4).

2. Whole organism's regulatory function of Rlung. Mkhris. Badgan. their

thermodinamical basis and participation of membrane - redoxy potentials 3

state line system.

The reason why the theory of Traditional medicine, relating to whole organism's

regulatory function of Rlung. Mkhris. Badgan. their thermodinamical basis should be









In old sutars of Traditional medicine it was stressed that ". . . If mkhris existed in

adequate equal forms, which forms the "heat energy" of organism, it provides the

nutrition and substrates, necessary to function of all organism ...If badgan is existed

in equal balanced state, which adds the weight and fat, protects the losses of nutrient

substrates, ensuring the longevity of life . . . ".




59

In basis of theory of Traditional Medicine we came to conclusion, that such

formulation on whole organism's regulatory function of rlung, mkris, badgan is closely

connected with thermodynamical process, which constantly takes place within living

organism (M.Ambaga, B.Sarantsetseg 1990), including membrane-redoxy

potentials 3 state line system.

Fluidity alpha state of membrane structures with high level of oxidation potential with

high level of heat energy formation, middle intensity of high energy phospha te - ATP

generation, of high energy electrons - NADPH generation, having more cis -

configuration (L.Strier 1985) is created unorderly thermodynamic state, in same

system of MS (E.A.Borodin et all 1981, 1985) unavoidly increased the probability of

transition all usefull energy (U) to useless unreversible heat energy (Q) with more

lossess of free energy (F).

In such way, in thermodynamical system, where is prevailed alpha state of

membrane structures with high oxidation potential of membrane-redoxy potentials 3

state line system, when created the condition of transferring of proton gradient to

heat energy, not to generation of of high energy phosphate - ATP, of high energy

electrons - NADPH "thermodynamic process is going in direction to more losses of

useful free energy (F), and to more dispersion of useless "heat" energy (Q) i.e

thermodynamic process of transition F-TS is directed to decrease of F, and gradually

increase of Q, TS, which probably may serve the guidelines of right interpretation of

theory of Traditional medicine "... mkhris forms "heat" and provides the necessary

energy to normal function of organism . . . But excessively increase of mkhris burnes

the all the energy and the nutritients of all organism . . . ".

While betta state of membrane structures with high reduction potential of organism

creates more stabile "thermodynamic" system, in such system due to trans -

configuration of saturated fatty acids and cholesterol (L.Strier 1985), when created

the condition of transferring of proton gradient not to heat energy, to generation of of

high energy phosphate - ATP, of high energy electrons - NADPH, thermodynamic

processes accompanied with more reservation of free energy (F) and less dispersion

of heat (Q, TS) energy i.e thermodynamic reaction proceeds in direction: to gradually

increase of F, and to decrease of Q, which are expressed in Traditional Medicine as

". . . Badgan addes the weight of organism, protectes the nutrient from burning and

gives possibility to long life ... ".

As regads to intermediate gamma state, when created the condition of less

generation of proton gradient, thereby formation of heat energy, and generation of

high energy phosphate - ATP, of high energy electrons – NADPH became diminished

"which by our openion, conditioned the all external patterns of rlung abstract




60

theoretical expression is unstable "thermodynamic system" where "thermodynamic

reaction is proceeded in minimum level of free energy /F/ and maximum level of

enthropy /TS/ ".

Apart from this there can be reasons to say that theory of MTM on whole organism's

regulatiory role of "rlung, Mkhris, Badgan" has close connection with action of

symphatic /SNS/ and parasymphatic /PNS/ nervous system, because of recruitment

the fluid state of MS with high oxidation potential created precondition of activation of

SNS, while recruitment betta - state of MS with high reduction potential and high

viscosity created precondition of activation of PNS, while formation of betta - state of

MS leads to activation of PNS, external signs of which has more similarity with

―appearance‖ of cold, stupid, heavy mucus characteristics ―Badgan‖ /M.Ambaga

1991/.

Picture №6

The comparative theoretical analysis of philosophical basis of fiveelements

theory of Oriental Medicine

In connection with this principle that theory of five elements of Oriental medicine

expressed by thermins as ―fire‖, ―water ‖, ―earth ‖, ―rlung‖, ―cosmos‖, ―wood‖ ―iron‖

had been formed as abstracted, not really existing elements, it would be more

interesting, if clarify these following guestions:

When, how had appeared the theory of five elements in the result of revealing which

external patterns and identifying it with what really existing things.

Tº

The occurrence of solidization and fluidization process in MS

F - the melting fluid alpha state of MS (K-III) F+S-the intermediate gamma state (M-D) S-Solid betta state (D-L) Q-L, L-1, L-2- the boundary of

transforming the fluid alpha state to solid betta state. L-Q, Q1, Q2 -the boundary of transforming the solid betta state to fluid alpha state Q-the point of fluidization of MS

L-the point of solidization in MS M-the alpha part of gamma - state of MS D-the betta part of gamma - state of MS

40

30

20

10

F

F+S

S

Unsaturated Saturated Fatty acids ratio (%)

Q-2

Q-1

Q

M

K

D

L

L-1

L-2




61

In appearing the theory of five elements what thing had been played the role of

material, really substance, existing in side of human body.

We, by using the new methodological approach ―Substance external properties

abstraction‖, ―taking in attention the such principle that‖ . . . five elements such as

fire, water, earth, rlung, are not the really existed elements . . . five elements are

abstracted symbols, which appeared in order to make easy to understand to people

and in the result of perceiving the following external forms, colours . . .‖ came to

conclusion that:

1. The theory of five elements in Oriental medicine had formed in the basis of

common philosophical views i.e. it had differentiated each other by that, what

thermins had been used, and had not differentiated what thing to be symbolized,

abstracted.

2. Between five elements theory Traditional Medicine did not existed such sharp

differences, but among researchers existed many controversial views in this regard.

3. The reason, why in Oriental Chinese medicine used thermins as "wood", "iron" and

in Traditional medicine used such thermins as "water", "rlung", "fire" may be

explained by this circumstances, that thinkers of this time had resort to identify own

recognized things with such things, with which had been encountered (faced with) in

every day life.

By using the methodological approach and new conception as "substance - external

properties - abstraction", "rlung, Mkhris, Badgan abstract thermin - membrane -

redoxy potentials 3 state line system "we are managed to reveal that the role of

"material substance" leading to appearance of abstracted five elements theory in

Oriental Medicine and which had been secretly existed behind such external signs -

patterns as: hot, cold, cool, sharp, fullness, emptiness, activated, slow, dampness

may be played the membrane - redoxy potentials 3 state line system of human body

and their 3 basic states: fluid alpha state of membrane structures with high oxidation

potential, solid betta state of membrane structures with high reduction potential,

gamma state of membrane structures with slow redoxy potentials i.e. behind hot,

sharp, acrid, activated external properties of abstracted elements "fire", "wood" had

existed the thermogenic, "enzyme - receptor" activated fluid alpha state with high

oxidation potential, belonging to membrane - redoxy potentials 3 state line system,

while, behind cold, cool, heavy, passive, slow, dampness external signs of abstracted

elements "water", "earth", "wood" had been existed the ATP - syntethizing

energyaccumulating, thermolimited solid betta state with high reduction potential

belonging to membrane - redoxy potentials 3 state line system of human body

(Picture N 5).




62

To questions of explaining the identity and difference of theory Yang-Yin and

theory rlung. Mkhris. Badgan in the framework of new conception "rlung.

Mkhris, Badgan – membrane - redoxy potentials 3 state line system ".

The reason why the identity and difference of theory Yang-Yin and theory rlung.

Mkhris. Badgan should be explained in the level of membrane - redoxy potential 3

state line dependent systems as 4 compartments and 10 functional systems

comprising all 14 trillion cells of human body, it is connected with these facts that

there are not really existed a human species as ―Homo sapiens plus rlung, mkhris,


containing the 14 trillion living rlung, mkhris, badgan, yin, yanalong with 14 trillion




During comparative theoretical investigation, which has been conducted by

using the new methodological approach "External patterns - theory of five elements",

"Substance - external patterns - abstraction" we came to conclusion that the theory of

Yang - Yin and the theory of rlung, Mkhris, Badgan in Mongolian and Korean

Traditional Medicine had formed in the result of converting the theory of five elements

to specific object of thinking i.e. theory of five elements and theory Yang -Yin, rlung -

Mkhris, Badgan are two unseparately steps of recognition of one things-one

substance. The this our conclusion has been confirmed by theoretical expressions,

written in the "The yellow emperor's classic of Medicine" (1995) as, ". . . The

elements of fire and water are categorized into yang and yin, the fire being yang and

the water being yin…".

Also, we had revealed such close relationship, which can be expressed as: Yang –

Mkhris - fluid alpha state of membrane structures with high oxidation potential, Yin –

Badgan - solid betta state of membrane structures with high reduction potential.

In order to confirm this close relationship we are drawing the below evidence:

A.Theoretical expression on whole organism's regulatory role of Yang-Yin and

rlung. Mkhris. Badgan and their membrane - redoxy potentials 3 state line

system. equivalents

The whole organisms regulatory role of Yang, Yin and Mkhris, Badgan had

expressed in theory of CKTM (The yellow emperor's classic of medicine, 1995), as: ".

. . energy requirement of human body compensated by increasing of Yang, while

energy preservation had ensured by increasing of Yin. . .Yang is the energy, the vital

force, the potential, while yin is the substance, the foundation, the mother that gives

rise to all this potential. . . ", in theory of MTM as: ". . . If Mkhris existed in equal

forms, which forms the "heat" of human body, provides the energy, nutrition and

substrates, necessary to function of all organism ... If badgan is existed in equal




63

state, which adds the weight and fat, protects the losses of substrates, ensuring the

longevity of life. . . " i.e. it was became appearant that the theoretical expression of

MKTM on the whole organisms regulatory role of Yang - Yin and Mkhris, Badgan had

more similarity, in otherwise, by abstract thermins of Yang, Mkhris in MKTM

considered the situation, how in human body has been occurred the process of

energy consumption, while by abstract notion of Yin, and Badgan in MKTM has been

showed the general feature of energy preservation process inside of human body.

What about membrane mechanism and thermodynamic equivalents of theoretical

expressions of KMTM on the whole organisms regulatory role of Yang - Yin, and

rlung, Mkhris, badgan we are concluded that the prevalence of fluid alpha state of

membrane structures with high oxidation potential in energysynthetizing membrane

structure leads to increase of bind energy - enthropy /TS/, decrease of free energy

/F/ by O/ P mechanism (oxydation : phosphorylation), accompanying with more heat

energy formation and external signs of these above mentioned membrane based

process summarized in the theory of KMTM as "hot", "sharp", "activating" external

properties of Yang, Mkhris and as increase of Yang, Mkhris hot, thi decreaie of Yin,

Badgan cool and increase of body heat.

In other case, the predominance of solid betta state of membrane structures with

high reduction potential in the energy - synthetizing membrane structure of human

body, associated with excessive formation of free energy - ATP and less formation of

bind, heat energy /TS/, and this membrane based process conditioned the more

energy preservation and limitation of heat energy formation, which may be expressed

in the theory of KMTM as increase of Yin cold and Badgan cool characteristics.

The results of all above mentioned theoretical comparative analysis has been

showed that the membrane – redoxy mechanism of theory of KMTM on whole

organism's regulatory role of Yang -Yin, rlung, Badgan, Mkhris can be explained by

following close relationship as: "Yang, Mkhris - fluid, alpha state of MS with high

oxidation potential - decrease of ATP synthesis - increase of heat energy formation -

decrease of energypreservation - appearance of "hot", "sharp" external patterns of

Yang, Mkhris", and "Badgan, Yin - solid betta state of membrane structure with high

reduction potential - increase of ATP synthesis - increase of energy preservation –

decrease of energy losses and thermogenesis - appearance of "cold", "cool" external

patterns of Yin, Badgan" and so the first way of increase of solid betta - state of all

membrane structures with high reduction potential in winter gives the possibility to

discover the matte r of theory of Traditional Medicine ". . . in winter, under action of

cold badgan to be stored, but concealed by cold.. . " (BJigmed 1988).

The second way of increase of betta state of membrane structure with high reduction

potential directly connected with the thermin of Traditional medicine ". . . warmth of

the sun in spring causes "Badgan" to arise . . ".

But if excessively increase of betta - state (trans - configuration) in spring potentiated

by low temperature and saturated fatty acids, cholesterol (Y.A.Vladimirov 1983) leads




64

to "cold - depending phasic transition of membranes with high reduction potential"

with following abruptly losses of activity of membrane binding enzymes and receptors

(M.E.Kreps 1981), which had expressed in MTM by following notion: ". . . if in spring

heavy and oily qualities combined with coolness stored, arises "Badgan" ailment . . ".

And so measurements of prevention from disease due to "cold-depending phasic

transition" must be directed to establishment of proper membrane states by rationale

use of foods and clothes in spring and autumn.

B.The similarity og theoretical expressions of KMTM on general characteristics of

Yang-Yin and rlung. Mkhris. Badgan and membrane structures.

During our comparative investigation we had revealed that hot, sharp, hot-oil,

fullness, activated, light external characteristics of Yang-Mkhris are closely connected

with hot, sharp, hot oil, fullness, activated, light external properties of abstracted

elements "fire", "wood", and behind such general characteristics of Yang, Mkhris,

abstracted elements "fire", "wood" had existed the process of intensification of heat

energy formation and activation of "enzyme - substrates", "hormone -receptor"

interaction, which had been carried out in the background of predominating the fluid-

alpha state of membrane structure with high oxidation potential.

Also, it can be say that "cold", "cool", "passive", "slow", "dampness" general

properties of Yin, Badgan had existed in close relationship with "cold", "cool",

"passive", "slow", "dampness" general characteristics of abstracted elements "water",

"earth", "iron", the molecular, membrane mechanism of appearance of such general

characteristics of Yang, Badgan and abstracted elements "water", "earth", "iron"

would be explained by activation of ATP-energy synthesis, energy accumulation

limitation of heat energy formation and inhibition of activity of membrane binding

enzymes and receptors, owing to prevailing of solid betta state of membrane

structures with high reduction potential (Picture N5).

In such way the results of our comparative investigation allows to conclude that

theoretical expressions of KMTM on external signs of Yang - Yin and Mkhris, Badgan

did not distinguished by philosophical basis and inner substance level i.e. the unique

role of inner substance in regarding lo externally distinguished general characteristics

of Yang-Yin, Mkhris - Badgau played the solid betta state of membrane structures

with high reduction potential and of fluid alpha state of membrane structures with

high oxidation potential.




65

G General characteristics of human body

regulation, when established the normal

status coded by abstract Mkhris thermin

G General characteristics of human

body regulation, when established

the normal status coded by abstract

Yang thermin

Mkhris

1.Hot

2.Sharp

3.Hot oily

4.Light

5.Bad smelling

6.Quality

7.Moist

Yang

1. Hot

2. Fullness

3.Quickly

4. High functionalactivity

Ac

5.Powerfull

6.Light mobile

7.Positive

8.Transparent




Badgan thermin




Yin thermin

Badgan

l.Cool

2.Heavy

3.Cool oily

4.stupid

5. Gentle

6. Firm

7.Sticky

Yin

l. Cold

2. Heavy

3.Passive

4.Low functionala

5.Slow

6.Negative

7. Sticky

8.Dark

The appearance of such pathological signs: as high temperature, thirst, acute

intensive pain, acute attacks of disease during excessive pathological increase of

general characteristics of Yang, Mkhris are associated with intensive release of

pyrogenic prostaglandin Fl, presentation of "antigen" in the membrane surface of

macrophages and lymphocytes, activation "antigen-antibody" interaction and release

of many inflammation mediators in background of excessive increase of fluid alpha

state of membrane structures with high oxidation potential.While decrease of Body

heat, feeling of cold, slow indigestion, more sleeping, chronic duration of disease

which had been observed during excessive pathological increase of general

characteristics of Badgan, Yin are explained by inhibition of heat energy formation

/by O/P mechanism/, chronic shortage of heat energy, decrease of H+ - gcneration

and HCL-synthesis, inactivation of "antigen" presentation on macrophage




66

membrane structure anddecrease of-excitability of excitable membranes in the

background of solid betta state of membrane structures with high reduction potential.

A. Ge neral characteristics of

human body regulation, when

established pathological status coded

by abstract Mkhris thermin

1. High temperature

2. Great thirst

3. Shooting pains

4. Quicly subjects to treatment

5. Yellowing of the Urine

6. Much vapor

7. Yellowing of tongue

8. Sees white objects as yellow

9. Fast pulse

10. Attaction to cold

11. Bitter taste in the mouth Ill ness is

strongest at noon

Ge gneral characteristics of human


pathological status coded by

abstract Yang thermin

1. High temperature

2. Thirst

3. S Sharp attack of disease

4. Feeling of heat

5. Darkening of urine

6. Attaction to cold

7. Talkativeness

8. Bitter taste in the mouth

9. Yellowing of tongue

10. Quicly undergoes to treatment

A. General characteristics of human


the pathological status coded by

abstract Badgan thermin

1. Diminishing of Bodily warmth

2. Inability to digest food

3. Bodily heaviness

4. Abundance of Saliva and Mucus

5. Much sleep, loss resistance to cold

6. Frequent chronisation of Disease

7. Poor appetite

8. Less odour and vapor of Urine

9. Attaction to warmth, wants hot place

10. Weak, slow pulse

11. Diarrhea

12. Pale tongue

Gen General characteristics of

human body regulation, when Esta

established the pathological status

coded by abstract Badganthermin

1. Constant coldness of body

2. Cold feeling

3. Wants to hot place, food

4. Frequent urination

5. Loss resistance to cold

6. Loss of appetite

7. Physical and Mental heaviness

8. Weak digestion

9. Swelling of Body

10. Slow, weak pulse




67

The theory of Yang - Yin and rlung. Mkhris. Badgan in regarding to healthy

existing of human body and membrane-redoxy potentials 3 state line system.

The theory of Tibetan - Mongolian, Korean Traditional Medicine in regarding to

healthy existing condition of human body had more similarity i.e. in the theory of KTM

this question is expressed as ". . . precondition of healthy existing of human organism

is preservation of normal balance between Yang and Yin . . . ", in the theory of MTM

as: " . . . precondition of healthy existing of human organism is equality which

established between rlung, mkhris, badgan . . . ". It can be say the membrane -

redoxy mechanism of above mentioned theoretical expression may be explained by

establishing the normal balance between three basic states as fluid – alpha state

of membrane structures with high level of oxidation potential with high level of heat


high energy electrons - NADPH generation and solid betta - state of membrane

structures with high level of reduction potential with high middle level of heat energy

formation, high intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation, as well as intermediate gamma state of membrane


gradient generation, low level of heat energy formation, low intensity of high

energy phosphate - ATP generation, low intensity of of high energy electrons -

NADPH generation under various unpleasant actions, environmental influence,

resulting to gain useful adaptation reactions.

C. Theory of Yang - Yin and rlung, Mkhris, Badgan about reason, provocating the

disease and membrane - redoxy potentials 3 state line system.

According to the theory of KTM ". . . Every disease has been provocated in the basis

of disturbance of balance between Yang and Yin . . . ", while according to theory of

TMTM ". . . The reason of disease is losses of balance (disbalance) between rlung,

mkhris, badgan . . . ". The membrane mechanism of such similarity of theoretical

formulations of KMTM in regarding to main reason of disease is associated with

disturbance of balanced equality between basic three states as fluid - alpha state

of membrane structures with high level of oxidation potential with high level of heat


high energy electrons - NADPH generation, solid betta - state of membrane

structures with high level of reduction potential with high middle level of heat energy

formation, high intensity of high energy phosphate - ATP generation, of high energy

electrons - NADPH generation, intermediate gamma state of membrane structures

with low level of oxidation - reduction potential with low level of proton gradient

generation, low level of heat energy formation, low intensity of high energy





68

generation under action of pathogenic environmental factors, which at last, leads to

unability of human organism to conduct the normal adaptive reaction.

The principle "Fullness and emptiness" of Korean - Chinese traditional medicine

and membrane - redoxy potentials 3 state line.

Two of eight diagnostic and Treatment principle of Korean Chinese Traditional

Medicine are principle "fullness and emptiness" (Shin. Min Kyu 1995).

It can be say that, the principle "fullness and emptiness" shows the intensity of

response of human body to pathogenic factors and to action of medicinal

preparations. When in human organism prevails the "emptiness" it is demonstrated

the signs of slowing of response reaction to pathogenic factors and to action of

Medicinal preparations, while increase of "fullness" is accompanied with stimulating

the over response reactions.

During comparative investigation we are revealed that "fullness" of Korean Traditional

Medicine corresponds to "sharp" characteristic of Mkhris, while "emptiness" is existed

in close relationship with "stupid" characteristic of "Badgan", because according to

theory of Tibetan Mongolian Traditional Medicine the "sharp" characteristic of Mkhris

leads to suddenly attack of disease, shooting pains in all parts of a body, high

sensitivity to pathogenic factors and fast end of disease, the "stupid" characteristic of

badgan is contributed to frequent chronisation of disease, slow response reaction to

Medical treatment, Disease often got hidden, atypical forms.

In the result of comparative analysis we have find such close relationship, which can

describe as follows: "fullness - sharp characteristic of Mkhris - fluid alpha state of

membrane structures with high oxidation potential of immunocytes, accompanied

with over response reactions" "emptiness - stupid characteristics of badgan - solid

betta state of MS with high reduction potentials of immunocytes, accompanied with

suppressed response reactions". ur experimental data has been demonstrated that

increase of solid betta state of membrane structure with high reduction potential on

immunocytes after administration of cholesterol in dose 250 mg/kg in mices leads to

decrease quantity of immunocytes in 1.27 fold, antibody titer -1.38 fold,

immunostimulator effects of medicinal preparations in 1.2-1.42 fold (P<0.05) in

comparison to animals, in which induced the prevalence of alpha fluid state of MS in

immunocytes.

Basing on above mentioned experimental data we came to conclusion that decrease

of immune reaction intensity in connection with prevalence of betta state of MS with

high reduction potential on immunocytes leads to an appearance of external

patterns, which in Korean traditional Medicine is described under thermin

"emptiness", in Mongolian traditional Medicine under thermin "stupid" characteristic of

badgan.




69

The intensification of immune reaction intensity is due to increase of fluid alpha state

of MS with high oxidation potential on immunocytes accompanied with appearance

of some external patterns, which is expressed in theory of KTM by thermin "fullness",

in theory of Mongolian Traditional Medicine by thermin "sharp" characteristics of

Mkhris.

Our new suggestion /M.Ambaga, Kim Ki Chang 1996/ relating to close coincidence

of "emptiness" and "stupid" characteristics with "betta state of MS with high reduction

potential - dependent immune deficiency state" has confirmed by the results of

investigation of other authors /Li Song Hyo 1991, Kim Chang Gol 1991, Ching Tae

Uong 1991, Rak Uong Hun 1991/ during which they had established that the

appearance of "emptiness" is connected with decrease of immunocytes and antibody

synthesis, also Rehmannice glutinosae Epimedium sagitatum, Glycyrrhiazae

uralensis, which used for treatment of "emptiness" - like disease had possessed the

immunostimulator effects in the form of increasing the cell - mediated and humoral

immunity.

Such interpretation of principle "emptiness and fullness" gives us possibility to

increase immune reaction of a human body by using medicaments, which is used in

traditional Medicine for converting emptiness to fullness, "stupid" characteristic of

Badganto "sharp" characteristic of Mkhris.

The principle "exterior" and interior of Korean Traditional Medicine and

membrane-redoxy potentials 3 state line system.

Our studies have been showed that the principle "exterior and interior" of Korean -

Chinese Traditional Medicine corresponds to philosophic category "external patterns

and inner essence". If considered the principle "exterior and interior" in accordance

with new conception "Substance - external patterns - abstract notion " proposed by

professor M.Ambaga (1994) the principle "interior" corresponds to substances-inner

material secretive objects, while "exterior" is connected with external properties of

Ying, Yin. Judging by theory of Korean - Chinese Traditional Medicine in majority

case exterior and interior had identical origin i.e. interior hot - exterior hot, interior

cold - exterior cold, in this case establishment of right Diagnosis is very easy. But

there are such cases, when exterior is not corresponded to interior, in this case

establishment of right Diagnosis would become more difficulty /Kim Ki Chang 1996/.

We are attempted to explain the scientific essence of accordance and unaccordance

of "interior" and "exterior" In Korean Traditional Medicine by using the new

conception "Substance External patterns - Abstract notion" and "rlung, Mkhris, Badgan

abstract theory and membrane - redoxy potentials 3 state line system.

"In the result of conducting the comparative analysi s we are revealed that the

principle of accordance of exterior with interior corresponds to this situation, when

external patterns of human normal existence and disease are coincided with to this




70

process, which are initiated (occurred) in membrane - redoxy potentials 3 state line

system level (3 morpho - functional states of MS) i.e. hot, sharp, light characteristics

"Mkhris" and alpha state of MS with high oxidation potential. But there are situations

when external characteristics - outwardly manifested signs of mkhris, badgan and

Yin, Yang did not corresponded to this process, which is inwardly initiated in

membrane-redoxy potentials 3 state line system level i.e. externally hot, light, sharp

characteristics of Mkhris and internally solid betta state of MS with high reduc tion

potential. Such uncorrespondance of external patterns with inner substances are

described in Korean Traditional Medicine as exterior cold - interior hot, Exterior hot-

Interior cold.

Such scientific interpretation of "Exterior and Interior" principle of Korean Traditional

Medicine shows that in case of appearance of unaccordance of "Exterior and

Interior", the medical treatment should be directed to correct of Disturbances,

occurred in basic morpho - functional states of membrane - redoxy potentials 3 state

line system. Classification of five solid organs in relation to rlung, Mkhris, Badgan and

their membrane - redoxy potentials 3 state line system specifics.

According to theory of MTM ". . . solid organ liver-is the Mkhris dominated organ,

because it locates in the residence of general Mkhris becoming the path of

movement of normal and form changed Mkhris.

Results of our comparative investigation has been showed, that in membrane -

redoxy potentials 3 state line system of liver is accumulated the products of FROL

more intensively under direct action of high temperature (37°C, 47°C, 57°C, 67°C,

77°C, 87°C,) than other solid organs (4.2-7.5 fold P<0.05), which at last comfirmed

the prevalence of alpha - state of MS with high oxidation potentials in liver cells. In

conditions of such experiments we revealed very less formation of products of FROL

in Badgan dominated organs as: lung and spleen (M.Ambaga 1990), which served as

one proof of prevailance of betta - state of MS with reduction potentials in their

membrane - redoxy potentials 3 state line system. In favour of our suggestions the

results of other foreing authors showed more content of unsaturated fatty acids in

liver membrane - redoxy potentials 3 state line system (L.N.Bogatchkaj 1990,

A.I.Dimitrieva 1984), which is more powerfull modificator of alpha-state of MS with

high oxidation.

And so, predominance of alpha - state (UFA) in membrane - redoxy potentials 3 state

line system of liver cells in one hands conditioned more functional activity of liver

cells in connection with formation of more fluidity, less viscosity state (L.Strier 1985)

but in other hands which can be serve as the reasons of more sensitivity of

membrane structures of hepatocytes to various pathogenic factors (A.F.Bluger 1985,

1986, Y.A.Bladimirov 1984) in the form of provocation of cytolysis. On the results of

our investigation we established that peroral administration of UFA (alpha-state of

MS) on doze of 0,l ml/gr led to activation of antitoxical function of liver by 2.4 fold

(P<0.05) as compared to animals with administration of cholestrol (betta-state of MS)




71

on doze of 250mg/kg. But long time administration of UFA in mice (beginning from

two weeks) accompanied by 1.31 fold increase of end products of FROL in

membrane structure of liver cells, which are the proof of those, that more prevalence

of alpha-state of membrane structure in liver's membrane - redoxy potentials 3 state

line syste, which, sometimes will be entail the pathogenic consequences.

Theory of MTM on hot, acute disease of liver and alpha-state of MS of liver

Can be say that any form of pathology of liver cells proceeded in direct and

unavoidly involvement of Membrane disturbance in liver's membrane-redoxy

potentials 3 state line system, (A.S.Loginov 1985, M.Ambaga 1990, 1991) .

The reason why theory of Traditional medicine on hot, acute disease of liver should

be explained in the level of membrane - redoxy potential 3 state line dependent

systems as 4 compartments and 10 functional systems comprising all 14 trillion cells

of human body, it is connected with these facts that there are not really existed a

human species as ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus

vata, kapha, pitta‖, ―Homo sapiens plus yan, yin‖ as if containing the 14 trillion living

rlung, mkhris, badgan, yin, yanalong with 14 trillion living cells only postulated by



And so, we came to conclusion, that prevalence of alpha - state of membrane

structures in liver's membrane - redoxy potentials 3 state line system unavoidly leds

to appearance of "hot, acute" signs of liver disease, matter of which connected with

intensive disturbance of MS coupling with formation of thermogenic, protonophor

phorc on liver cell s membrane under pathogenic factors (Y.A.Lopukhin 1983,

A.S.Loginov 1986, A.F.Bluger 1986) and emergence of local rise of temperature in

projection zone to liver on body surface (VJ.Tariban 1986,1.N.Antonov 1989).

Results of our investigation showed that in first 0-3 days after acute toxic hepatit

(CCL4) in MS of liver increased the number of all products of FROL (alpha-state) of

membrane of liver cells in 1.62 - 6.2 fold (P<0.05), which possessed more

"thermogenic" and protonophore activity (J.Musil 1984, Y.A.Lopukhin 1985,

A.A.Linchevskaya 1989). Such disturbance of MS was also demonstrated by our

observation, which accompained with specific pattern of cytolysis as: serum activity

of ALAT and ACAT increased in 2 fold (P<0.05), decreased antitoxication function in

1.47 fold (P<0.05), bilesyntethizing activity in 1.8 fold (P<0.05).




72

Replaccmanl of alpha-state of MS of liver cells by betta state during

chronisalion of it s pathology and theory of MTM on cold badgan disease of

liver

During our experimental works we revealed that the first 0-3 days activation of

FROL in MS of liver cell after poisoning by CCL4 has been replaced by their

decrease during 7-28 days of experiments and all products of FROL decreased 1.16

- 4.8 fold (P<0.05).

Basing on this results we came to conclusion that towards chronisation of liver

pathology in it's MS, fluid alpha - state of MS with high oxidation activity was

replaced by solid betta - state of MS with high reduction activity, which is

expressed in theory of MTM as cold - badgan disease of liver. Our such suggestion

was also confirmed by results of other investigators /N.Decina 1990/ according to

that the process of chronisation of liver pathology accompanied by decreasing of

index of unsaturation with high oxidation activity of MS and number of UFA in 1.2 -

1.4 fold, and increasing cholestrol and stearic acids (more viscosity betta-state of MS

with high reduction activity), lowering the activity of antitoxic, proteinsynthetic

function (O.P.Greek 1988) and membrane-binding enzymes (cytochroma-P-450,

monoxygenasa, aminopyridinmethylasa). Also, we revealed more interesting fact,

that such increase of solid betta - state with high reduction activity in MS of liver

cells coupled with the process of malignization /cancer/ (L.Ivanova 1983,

A.P.Chohlov 1988) which often appeared as consequence of acute disease of liver

and described in MTM under thermin of cold - badgan disease of liver. Apart from

this, our new suggestion, related with the explanation of hot acute disease of liver in

connection with alpha - state, exhibiting the high oxidation activity of MS of liver

cells gives possibility to discover the secret formulation of MFM on hot, acute

property of bile.

By our opinion, this is connected with detergent and destabilization effect of bile on

alpha - state, exhibiting the high oxidation activity of MS of liver cells

(B.R.Gedullina 1986), which is coupled with formation of protonophor, thermogenic

phore of MS of liver cells /M.Ambaga, B.Sarantsetseg 1991/.

Structural specifity of Badgan dominated organ - lung and theory of MTM on

cold badgan disease of lung

According to our investag'ation's results the intensity of induction of FROL on MS of

lung under action of high temrepature was 1.5 - 2.4 fold lower than other organs,

which served as the main proof of prevalence of betta - state, exhibiting the high

reduction activity on it's membrane structure.

By our suggestion, predominance of solid betta - state with the high reduction

activity on MS of lung played on important pole in increasing it's resistance to

harmful external factors /M.Ambaga 1991/.




73

Our results coincided with results of other scientist's, which has been demonstrated

more content of palmitic and stearinic fatty acids with the high reduction activity

(betta-state), less number of UFA on MS of lung /E.G.Serebrennikova 1989,

V.I.Kulitchkaya 1984/ and less intensity of FROL /P.Z.Meerson 1984/. On these basis

we came to conclusion that theory of MTM about ". . . lung as badgan organ . . ."

directly linked with it's betta - state of MS in connection with this cold badgan disease

of lung also due to excessively of solid betta - state of MS of lung. Our such

suggestion appeared in basis of results of our investigation, where we revealed that

excessively increase of betta state of all organism's membrane structures by peroral

administration of cholestrol in dose of 250 mg/kg resulted to decrease of pulmonary

resistance to toxic action of adrenalin in form of increase of index of lung swelling, on

the contrary, administration of UFA (alpha-state of MS) leads to 1.3-3.6 fold decrease

of such pathogenic parameters, i.e. improved pulmonary resistance.

Our results and suggestion were also confirmed by the investigation of other

scientists, who found more decrease in number of UFA, more increase in number of

cholestrol, palminitiv acid, sphingomyelin during lung disease /P.A.Kazaryan 1984,

M.A.Chasina,1987, A.M.Masuev 1991/, and excessive quantity of cholestrol leading

to disturbance of capillary vessel of lung, a formation oi microform of atelectasis.

Owing to revealing the process of subsequent, pathogenic changes of basic states

on MS of liver cells as: when increased because of pathology the fluid alpha state of

membrane structures with high oxidation potential, high level of proton conductance

and high level of within membrane - redoxy potentials 3 state line system, that

provided the normal existence of all cells by ensuring normal flow of electrons,

protons with generating the proton gradient were substituted by the solid betta

state of membrane structures with high reduction potential, middle level of

proton conductance and middle level of proton leak, during transition from acute

stages of disease to chronisation, malignisation of liver's pathology and also it's

relation to theory of MTM on "acute hot" and chronic "cold badgan" disease of liver

and other organs we suggested new principle of prevention from chronisation and

malignisation (cancer) by preservation of normal alpha-state of whole organism's

membrane structures within membrane - redoxy potentials 3 state line system.

Theory of MTM on seasonal changes of function of five solid organs and their

relationship with seasonal changes of all organism's membrane-redoxy


The reason why theory of Traditional medicine on seasonal changes of function of

five solid organs should be explained in the level of membrane - redoxy potential 3







74






Autumn. According to theory of MTM: ". . . in autumn, the functional activity of liver is

deteriorated, which yet complicated by "enemy acts" of lung in at titude towards them

. . . "

The scientific essence of abovementioned process may be explained by intensifying

of FROL because of the excessive, liquid phase transition within membrane - redoxy

potentials 3 state line system, which occured in MS of liver cells as (1 + 2) i.e (1-

means the excessive contents of unsaturatedfatty acids in MS of liver cells, (2-

means the autumn season depending increase of alpha-state of MS transition with

high thermogen and oxidation activity, protective against cold provocated solid phase

transition action within membrane - redoxy potentials 3 state line system by

homeoviscous adaptation reaction. What about enemy action of lung, this is

connected with increase of active form of oxyden through respiration - oxygen

acceptor functions of lung.

During our observation we revealed that in autumn season in all organism's

membrane-redoxy potentials 3 state line system, coefficient growth of FROL is

increased in 1.28 - 1.63 fold (P<0.05), also "acceptor property" of MS in relation

to cholestrol in 3 fold (P<0.05) as compared to spring, which shows increase

in number of UFA (alpha - state of MS with high oxidation activity).

Can be say that such change in number of UFA (alpha-state of MS with high

oxidation activity) might exert various effect an all solid organs, depending on their

specifity of membrane - redoxy potentials 3 state line system. As to liver cells MS

threatened the probability of attack of "heat - depending phasic transition" due to

mechanisms "alpha + alpha form increase of fluidity of membrane structures ".

Such suggestion confirmed by the results of our investigation that in membrane-

redoxy potentials 3 state line system of liver cells in summer the coefficient growth

of FROL is increased in 1.1-2.3 times (P<0.05) under action of high temperature as

compared to spring; in direct connection with this the resistance of membrane

structures of liver cells to toxic prooxidant action of CCL4 and H2O2 decreased to

1.66-2.1 time (P<0.05), deteriorating it's antitoxic and bilesynthetized function in 1.13-

1.5 fold (P<0.05).

Also in favour of our these propoasals we demonstrated in autumn more decrease of

bilesynthetizirrg, antitoxic activity of liver cells in 1.81, 1.32 times (P<0.05) more

increase in number of products of FROL in membrane-redoxy potentials 3 state

line system of liver cells (in 1.52-3.47 times) in animals, when overloaded by




75

unsaturated fatty acids (P<0.05) in dose of 0.1 ml/20 gr; scientific matter of such

pathologic process lies in more increase of alpha-state of MS /more fluidity/ by

mechanisms /alpha + alpha / in autumn. Apart from this we discovered scientific

matter of theory of MTM on ". . . in autumn the activity of lung is increased which is

connected with changes, proceeding in membrane - redoxy potentials 3 state line

system of lungs as follows: alpha against betta i.e. seasonal increase of alpha-state

of MS with high oxidation, high proton conductance, high proton leak in autumn

prevents the excessive rise of betta - state of membrane - redoxy potentials 3 state

line system with high reduction, low proton conductance, low proton leak in

lungs with following improvement of their function, because we demonstrated that

administration to animals of UFA (alpha-state of MS with high oxidation, high

proton conductance) increase the pulmonary resistence to toxic effect of adrenalin

(in 1.3-1.7 time P<0.05), and such rise of pulmonary resistance (P<0.05) to toxic

effect of adrenalin is found in summer, as compared to other seasons (winter and

spring).

As regards to enemy acts of increased function of lung to deteriorated function of

liver in autumn, which is connected with prooxidant effects of oxygens, bringing

through activated lungs in attitude to alpha-state of MS(UFA) of liver cells,

accompanied with distruction of it's membrane structures by mechanisms: RH+O2T=

R'+O+OH-.

And so, seasonal change of alpha - state of MS in autumn can be exerted negative

action to MS (alpha-state) of liver, by mechanism (alpha + alpha states ), from which

could be protected with the help of stopping the excessive fluidization of liver's MS

and low temperature.




76

THE INFLUENCE OF SOME FACTORS, WHICH INCREASE THE ABSTRACTED

MKHRIS (YANG), AND THE BADGAN (YIN) CODE ON THE PHASE TRANSITION

OF MEMBRANE –REDOXY 3 STATE SYSTEM OF HUMAN BODY.

Picture № 7

Spring.

Judging by theory of TMTM ". . .in spring the functional activity of lung is deteriorated

and increased the function of liver.

Can be say that the deterioration of liver cells in spring has connected with excessive

Solid phase transition of MS in this season in the form (1+2) i.e. (1-means the

excessive contents of saturated fatty acids in MS of lung, (2-season depending

increase of betta - state of MS in spring in according to adaptation-loss reaction.

Our new conception “Mkhris, Rlung, Badgan - membrane - redoxy potentials 3

state line system “gives the possibility to explain the essence of theoretical

expresson of TMTM ". . . if cold combined with heavy oily which leads accumulation

of the Badgan. . . " in close connection with solid phase transition of MS membrane -

redoxy potentials 3 state line system”

In such way the theoretical expression of TMTM... if hot and hot oily combined, which

leads to accumulation of Mkhris... may be interpreted in close connection with liquid

phase transition of MS. Also should be emphasize that the all things such as hot, hot

oily food, medicine, horse, marmot meat, autumn season, directeffect of Sun, middle

age, liver organ, which expressed in TMTM by thermins the Mkhris had effect to

Tº

The factors, which expressed under abstract thermin “Mkhris” (yang) and alpha state of MS with high oxy potentials.

Hot

Hot oily medicaments, foods

(horse, marmot meats and oils)

Spring season

Sun heat

Middle age

Liver

40

30

20

10

Unsaturated Saturated

Fatty acids ratio (%)

α state+oxy potential

γ state+low redoxy

potential

β state+red potential

The factors, which expressed under abstract thermin “Badgan” (yin) and betta state of MS with high red potentials .

Cold

Cold oily medicaments, foods (beef, goat meats, milks)

Spring season

Low temperature effect

Young age

Lung, spleen, kidney




77

increase the alpha - state of MS membrane - redoxy potentials 3 state line

system”, while the all things such as cold, cold oily food, medicine, beef-goat meat,

spring season, cold effect of weather, young age, which expressed in TMTM by

thermins the Badgan, had effect to increase the betta - state of MS membrane -

redoxy potentials 3 state line system”.

Our investigation results showed the increase of intensity of FROL in all membrane

structures within membrane-redoxy potentials 3 state line system in 1.46 fold

(P<0.05) and decrease of cholesterol acceptor activity of MS in 3.1 fold (P<0.05) in

spring as compared to autumn, which served as one proof of increase of betta - state

of MS in the same season.

Such increase of betta - state of MS has exerted negative effect on functional activity

of lung by mechanism (betta+betta)-i.e by excessively solidating of MS within

membrane - redoxy potentials 3 state line system, which was confirmed by our

observations as: in spring the pulmonary resistence to toxic effect of adrenalin

decreased in 1.3-1.7 fold (P<0.05), also tolerance to prooxidant action of CCL4, H2O,

deteriorated by 1.2-1.6 time (P<0.05) and administration of cholestrol in dose

250mg/kg decreased the pulmonary resistance to adrenalin in 1.16 -1.46 time as

compared to other seasons.

Results of our investigation, conducted in spring served the basis of explaining the

theory of Mongolian Traditional Medicine ". . . in spring the functional activity of lung

is deteriorated ..." in close connection with membranedepending process within

membrane-redoxy potentials 3 state line system.

A contrary to this the such seasonal increase of betta-state of all organism's within

membrane-redoxy potentials 3 state line system in spring leads to increase of

functional activity of liver cells, which is linked with decrease of vulnerable alpha-

state of MS in liver cells i.e stabilization the MS of liver thanks to the increase of

betta-state (Yu.M.Lopukhin et all 1983, G.I.Klebanov et all 1986) of MS in spring.

Such suggestion confirmed by the results of our investigation: in spring tolerance of

membrane-redoxy potentials 3 state line system of liver to prooxidant action of

CCL4 H2O2 in 1.95-2.1 fold (P<0.05) and also*intensity of accumulation of products of

FROL on MS of liver decreased in 2.23 time (P<0.05) in spring.

Basing on the results of such experiments we came to conclusion that theory of

Mongolian Traditional medicine on ". . .increase of function of liver in spring . . . can

be explained by mechanism of change of MS, which proceeds in within membrane-

redoxy potentials 3 state line system of liver cells in the from as: betta - against-

alpha states.




78

Relationship between the theory of Rlung. Mkhris. Badgan and "FROL(free

radical oxidation of lipids)-AO(antioxidants) systems".

The reason why the relationship between the theory of Rlung, Mkhris. Badgan and

"FROL(free radical oxidation of lipids)-AO (antioxidants) systems should be



body , it is connected with these facts that there are not really existed a human



mkhris, badgan, yin, yanalong with 14 trillion living cells only postulated by Traditional

medicine doctors , all their diagnostic and treatment methods based in this form of

human specie, but categorically resisted, refused by NCM medicine.

During interpretation of the theory of rlung-mkhris-badgan in framework of our new

conception "rlung, Mkhris, Badgan - membrane-redoxy potentials 3 state line

system" we revealed the close relationship between abstract notions of rlung,

Mkhris, Badgan of MTM and systems of "AO-FROL", which exerted direct effect on

normal regulation of three basic states of MS (Yu.A.Vladimirov 1971, 1987,

E.B.Burlakova et all 1989).

All things, which is expressed by thermin of Badgan (by our opinion connected with

betta-state of MS within membrane-redoxy potentials 3 state line system),

regarding to human age, organs, seasons, dietary factors, function (lung, young age,

spring) corresponds to middle level of AO systems.

While things, which expressed in MTM by thermin of Mk hris (by our opinion is linked

to alpha-state of MS), regarding to age, season, all organism's regulatory function,

solid organs (liver, autumn, middle age) and corresponds to high level of AO

systems.

The things, which expressed on MTM by thermin of rlung (by our opinion-gamma-

statc of MS within membrane-redoxy potentials 3 state line system) regarding to

heart, juncture of spring and summer, old process, and corresponds to unstable low

levels of AO defence systems.

Significance of such interpretation of theory of MTM on "rlung, mkhris, Badgan" in

connection with antioxidant (AO) defence systems directed to elaborate new principle

of prevention and treatment of various disease of solid organs and obesity, ageing

process by the using of antioxidant preparation of natural origin strongly regarding

the age, seasons, and organ's specificity.

In favour of our new suggestion "rlung, Mkhris, Badgan - membrane - redoxy

potentials 3 state line system" showed all results of investigations conducted by us

with peroral administration of cholesterol and unsaturated fatty acids, first of which

are creator of alpha - state of membrane structures while second (SFA) are the main




79

parts of betta - state of MS within membrane - redoxy potentials 3 state line system

(Ya.Kagava 1985, L.Strier 1985); and so, whole organim's external signs of peroral

administrated cholesterol (betta - state of MS with high reduction activity ) in animals

are expressed as follows: decrease of resistance of animals to coldris to add the

weight of animals, more intensively accumulation of cholesterol in spring (probably by

mechanism: (betta + betta); increase the resistance of MS of liver cells to action of

pathogenic factors (by mechanism (betta + betta); deterioration of the resistance of

MS of lung to action of pathogenic factors; decrease the level of functional activity of

spleen; increase in number of exsecreted urine. These all had very similarity with

external expressions of badgan, which are described in Oriental and Mongolian

Traditional Medicine.

While all organism's external signs of peroral administration of unsaturated ' fatty

acids (alpha-state of MS within membrane - redoxy potentials 3 state line system) in

animals are characterized: by increase of resistance of animals to cold; less addition

of weight of animals, less accumulation of cholestrol in autumn, probably by

mechanisms as alpha - againist-betta; increase the functional activity of lung and

spleen by mechanism's alpha - againist betta states of membrane structures within

membrane - redoxy potentials 3 state line system; decrease the functional activity of

liver i.e by mechanism's alpha+alpha decreased the resistance of MS of hepatocytes

to harmfull action of external pathogenic factors; decrease quantity of urine.

These all had very similarity with external expressions of Mkhris, which arc described

in Oriental and Mongolian Traditional Medicine. In such ways can be draw interesting

conclusion, that three basic state (alpha, betta, gamma) of MS within membrane-

redoxy potentials 3 state line system of all organism, outside of which could be

impossible for any appearance of functional regulation of all organs and cells at the

end led to creation of wonderfull abstract theory of rlung, Mkhris, Badgan.

The seasonal changes of "rlung. Mkhris. Badgan" and the membrane - redoxy

potentials 3 state line system of human body.

The reason why the seasonal changes of "rlung. Mkhris. Badgan" should be






mkhris, badgan, yin, yanalong with 14 trillion living cells only postulated by Traditional

medicine doctors, all their diagnostic and treatment methods based in this form of

human specie, but categorically resisted, refused by NCM medicine.

According to theory of MTM the seasonal changes of "rlung, Mkhris, Badgan" are

described in following forms: ". . . "Mkhris" are stored in late summer, arised in




80

autumn with it's qualities of oiliness and warmth, and are pacified by the coolness of

early winter . . .The cool, oily heavy qualities of late winter cause "Badgan" to be

stored, but they are concealed by the cold and thus do not arise. The warmth of the

sun in spring causes them to arise, and the light and rough qualities of early summer

pacify them . .. ".

THE SEASONAL DEPENDING CHANGE OF ABSTRACTED RLUNG,

MKHRIS, BADGAN CODE AND CHANGE INDUCED IN THE MEMBRANE –

REDOXY POTENTIAL 3 STATE SYSTEM OF HUMAN BODY

Picture № 8

It should be emphasized that if used our new suggestion "rlung, Mkhris, Badgan-

membrane structures" to explain this above mentioned fomulation of Traditional

medicine could be easely understand that such seasonal changes of "rlung, Mkhris,

Badgan" literally coincided with seasonal adaptation changes of basic three state

(alpha, betta, gamma) of membrane structures within membrane-redoxy


The human and animal's organism from beginning of summer started to prepare to

winter cold by increasihg fluidity alpha - state (unsaturated fatty acids) of MS, but in

contrary case will be occurred "cold - depending phasic transition" on all membrane

structures of organism with following abruptly lossess of their functional activity

Spring Badgan

Winter

Autumn Mkhris

Summer rlung

Redoxy system

Membrane system

β α

γ




81

(M.E.Kreps 1981) i.e will be appeared signs of various disease caused by cold

/M.Ambaga 1990/. Indeed, the results of investigation conducted by V.Ivanov et all

(1984) showed that the quantity of unsaturated fatty acids (alpha - state) were

increased in 1.35 fold and number of saturated fatty acids (p-state) decreased in 1.5

fold towards autumn and winter.

We also revealed, that the administration of cholesterol - (betta -state) of MS in mice

in dose of 250 mg/kg in winter leads to 1.2 fold decrease (P<0.05) the resistence of

animals by parameters of pulmonory insistence to acute loxic effect of adrenalin,

while administration of UFA (alpha-state) in dose of 0.1 ml/gr decreased this

pathogenic parameter in 1.4 fold (P<0.05) i.e. improved the to endurance of organism

to cold.

In other hands, increase of alpha -state of MS (UFA) towards winter.through autumn

ensured "thermogenic function" of MS, which is very necessary to adaptation to cold

(G.Suchova 1990, E.Z.Emirkov 1991).

Infortunately, if in autumn (juncture of summer and winter) preparatory increase of a-

state (UFA) to winter cold provoked by such supplement factors, as high

temperature, and UFA, which increased the fluidity (alpha - state) of MS within

membrane-redoxy potentials 3 state line system and leads to "heat-depending

phasic transition" on membranes with following lossess of all organism's

membranebinding enzymes and receptors (Y.A.Vladimirov 1983, L.Strier 1985). It is

of great interest, that our such suggestion confirmed truth of the theory of MTM ". .

.hot and oily qualities combined with warmth leads to arise Mkhris in autumn ..."

(Picture N 6, N 7).

Towards spring in all organism's MS created precondition of increase of solid betta -

state of membrane structures (saturated fatty acids and cholestrol), which by our

opinion proceeded in following two ways:

1. Way of losses of alpha - state of MS within membrane-redoxy potentials 3 state

line system.

In winter more quantity of alpha -state (UFA) with high oxidation activity within

membrane-redoxy potentials 3 state line system spended to production of heat

energy againist cold, which unavoidly leads to its decrease replacing by solid betta -

state of MS with high reduction activity within membrane - redoxy potentials 3

state line system (G.Suchova 1990).

2. Wav of adaptation

The prevalence of solid betta - state with high reduction activity within

membrane -redoxy potentials 3 state line system in spring serves as protective

mechanism from becoming excessively "fluidization" of MS (excessively increase of

alpha - state) under direct action of summer's warmth and on other hands, ensured

the mechanism of decrease of general metabolic activity of organism to comparative

high temperature of spring and summer (V.I.Smolyar 1987), which is very vital to

adaptation to warmth action of environmental temperature (Picture № 9)




82

THE EXPLANATION OF SCIENTIFIC ESSENCE OF DIETOTHERAPY METHODS

OF MONGOLIAN TRADITIONAL MEDICINE

The reason why the scientic basis of dietotherapy should be explained in the level of

membrane - redoxy potential 3 state line dependent systems as 4 compartments and

10 functional systems comprising all 14 trillion cells of human body , it is connected

with these facts that there are not really existed a human species as ―Homo

sapiens plus rlung, mkhris, badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo

sapiens plus yan, yin‖ as if containing the 14 trillion living rlung, mkhris, badgan, yin,

yanalong with 14 trillion living cells only postulated by Traditional medicine doctors ,

all their diagnostic and treatment methods based in this form of human specie, but

categorically resisted, refused by NCM medicine.

According to theory of Mongolian Traditional Medicine (MTM): ". . . Acute (acrid) and

hot oily foods (horse and marmot meat) increases "Mkhris" and contributes to

"Mkhris" disorders . . . Heavy, cold oily foods (beef and goat meat) increases

"Badgan", contributing to "Badgan" disease . . . ".

Undoubtly, that quality and composition of all organism's membrane-redoxy

potentials 3 state line system undergo to constant changes under direct action of

received foods (M.M.Levachev 1980, 1986, L.M.Yazeva 1980, 1981).

Number of investigation showed that Horse and marmot meat, which according to

theory of MTM increased "Mkhris", contained 61-68% unsaturated fatty acid (UFA)-

mainly components of alpha - state of membrane structure (MS) within membrane-

redoxy potentials 3 state line system (S.Masigsuren 1978, N.Jamsranjav 1978,

T.A.Valieva 1985, P.Dorjderem 1991).

While Beef and goat meat, which judging by theory of MTM increases "Badgan"

contained more quantity of saturated fatty acids (SFA) (59-60%)-mainly components

of betta - state of MS (P.Dorjderem 1991, B.Suchbaatar 1991).

Our suggestion, relating to that foods, increasing "Mkhris", contained more quantity of

UFA (alpha - state of MS) increased the resistance of human organism to cold; while

foods, increasing "Badgan", included more quantity of SFA (betta - state of MS)

increased the resistance of human organisms to hot has comfirmed by investigations

of other scientists who revealed that administration of UFA decreased the

susceptibility of animals to cold by decreasing the temperature of heart arrest from +

120C (by cholestrol) to 70 C (N.Kalabukhov 1985).

On the basis of abovementioned explanation of membrane mechanism of

Dietotherapy of MTM we have suggested the new principle of treatment, the essence

of which directed to use the foods, containing more quantity of UFA in winter cold

season and to use the foods containing SFA in summer hot season.




83

THE MEMBRANE MECHANISM OF ACTION OF FOOD FACTORS,

WHICH INCREASED THE RLUNG, MKHRIS, BADGAN

By our opinion, the membrane - redoxy mechanism of using beef, goat meat, oils for

treatment of hot Yang-Mkhris Disease, also using horse meat, oils during Yin,

Badgan Cold Disease may be explained by decreasing the excessive pathological

increased during Mkhris Disease fluid alpha state of MS within membrane-redoxy

potentials 3 state line system under saturated fatty acids, contained in goat, beef

meat, oils and by diminishing the excessive pathological increased during Badgan

Disease solid betta state of MS under direct influence of unsaturated fatty acids,

contained in horse meat, oils.

In this connection, we are putting before as the goals to carry out the comparative

study, directed to establish the influence of various ratio of " unsaturated: saturated

fatty acids" of horse, goat, beef meat, oils, possessing hot and cold taste, power,

property on the membrane state transition, membrane permeability and stability

within membrane-redoxy potentials 3 state line system.

THE MEMBRANE-REDOXY POTENTIAL 3 STATE MECHANISM OF ACTION OF

FOOD FACTORS, WHICH INCREASED

THE ABSTRACTED RLUNG, MKHRIS, BADGAN CODE.

Picture № 9

MEAT, OILS, MILKS

Alpha state of MS

with high oxy

potentials

Betta state of MS

with high red

potentials

Betta state of MS

with high red

potentials

Alpha state of MS

with high oxy

potentials




84

The result of our investigation shows that under action of horse oils, possessing hot

power, property according to theory of KMTM, containing more quantity of

unsaturated fatty acids (P.Dorjderem 1991) has been occurred the transition from

bette state with high reduction activity to alpha state with high oxidation activity in

membrane - redoxy potentials 3 state line system, increased the accumulation of

deprotonized products as MDA in 1.2 times /P<0.05/, the membrane permeability in

1.22 times /P<0.05/, contents of deprotonized products and conjugated products as

MDA, DK in the membrane structures in 1.21 times /P<0.05/ i.e. in such way the

increase of proton leak, thermogenic, protonophore activity of membrane structure

under direct effects of horse meat, oils may be expressed in theory of KMTM as

"hot", "hot oil", "sharp" power and property of foods /horse meat, milk/. Also during

our investigation we are revealed that under influence of goat, beef oils, possessing

cold, cool, cold-oil property, power according to theory of KMTM, containing more

quantity of saturated fatty acids (P.Dorjderem 1991) had occurred the transition from

alpha state with high oxidation activity to betta state with high reduction activity in

MS, increased the membrane stability in 2.01 times /P<0.05/, decreased the

deprotonized products and conjugated products as MDA, DK contents in membrane

structure in 1.8-2.12 times /P<0.05/, in otherwise the decrease of membrane

permeability, limitation of proton leak, thermogenic, protonophore function of MS

under direct effect of goat, beef oils may be expressed in the theory of KMTM as

cold, cool, cold oil power, property of foods /goat, beef meat, oils/.

During our comparative investigation have been observed by us such interesting

facts i.e. the essence of the principle of using the horse meat and oils possessing

hot, hot oil, taste, power, quality in KMTM to ensure the transition from "emptiness"

to "fullness " may be explained by occurring the transition from gamma state of MS

with low redoxypotentials to alpha state with high oxidation activity in MS under direct

effect of more quantity of unsaturated fatty acids, containing in horse meat, oils,

which, at last, resulted to activation of membrane binding enzymes and receptors

and intensification of immune response reaction and increase of "antigen"

presentation in immunocyte's membrane structures.

It would be interesting, if explain how use the membrane - redoxy potentials 3 state

line system related mechanism of provocation of hot-Mkhris (yang) and Cold-

Badgan (Yin) disease under direct effect of foods in every day treatment practice.

According to philosophical view points of oriental Medicine, the normal balance

between hot and cold is ensured the precondition of normal healthy existence of

human body. If normal balance between hot and cold has been disturbed by

unpleasant influence of Dietary, behavioural, seasonal factors, which resulted to

provocation of Disease, therefore, in this case it should be take the treatment

measure by using Dietary factors, medicaments, which possessed the opposite taste,

power, quality, regarding to excessive pathogenic factors.




85

One of conditions of the provocation hot-Mkhris (yang) disease is excessive use of

hot, salty, acrid taste power possessing foods, drinks such as horse , marmot,

donkey, mutton, chicken meats, alcohol drinks, garlic, onion et al.

The membrane-redoxy potentials 3 state line system related mechanism of

provocation of this pathological process is explained by inducing the excessive fluid

phase transition in membrane structure within membrane-redoxy potentials 3 state

line system under direct effect of unsaturated fatty acids, contained in horse, marmot,

chicken meats. In this case, for treatment, should be use beef, goat and fresh meat

of hybrid yak, calf, cold water from rocky and snow mountain, which blocked the

excessive predominance of fluid alpha state of MS within membrane-redoxy

potentials 3 state line system by increasing the solid betta state in MS within

membrane-redoxy potentials 3 state line system owing to containing the more

quantity of saturated fatty acids, cholesterol and limiting the local thermogenesis,

proton leak process around bioenergetic cell membranes.

The main reasons of provocation of cold disease because of long time use of beef,

goat, camel, yak meats, cold drinks, goat milk, fruit, vegetables, which contained the

more quantity of saturated fatty acids, cholesterols-main modificator of solid betta

state of MS and possessed the cold, bitter, sweet taste, power and quality are

remained more interesting.


provocation of cold disease under cold foods is explained by provocating the

excessive solid betta state with high reduction activity under direct effect of saturated

fatty acids, contained in beef, goat meat. In order to eliminate such pathological

situation, according to the theory of Oriental medicine had been recommended the

use of horse, marmot, sheep meats, alcohol, hot water, which decreased the solid

betta state of MS with high reduction activity by increasing the fluid alpha state of

MS with high oxidation activity. On the basis of above mentioned explanation of

membrane - redoxy potentials 3 state line system related mechanism of dietotherapy

methods of Oriental Traditional Medicine we have suggested the new principle of

treatment, which essence has been directed to use the foods, containing the more

quantity of unsaturated fatty acids - main modificator of alpha state of MS with high

oxidation activity winter cold season, and the use of foods, containing the more

quantity of saturated fatty acids - main modificator of solid betta state of MS with high

reduction activity in summer - autumn hot season.

To study the membrane - redoxy potentials 3 state line system - dependent

mechanism of theory Traditional Medicine on constitution types of Individuals.

The reason why the scientic basis of theory Traditional Medicine on constitution

types of Individuals should be explained in the level of membrane - redoxy potential 3





86

comprising all 14 trillion cells of human body , it is connected with these facts that




living cells only postulated by Traditional medicine doctors , all their diagnostic and



Judging by the theory of Traditional medicine ". . . Those, influenced by nature of

Mkhris have great thirst and hunger, yellow hair and bodies, a medum of wealth, life

span and bodily size . . . Those having the nature of Badgan have cool bodies,

obesity, pale complexion and the ability to endure the disease. They have large

bodies, long life and much wealth . . . People, who are influenced by rlung have

stooped - over form, are thin and of dark complexion, unable to endure cold or warm

. . .have few possessions and a short life span. They are light sleepers and have

small bodies, they enjoy singing and laughing . . .".

Can be say, that such classification of human constitution types in MTM may be

explained by "inborn" difference of membrane-redoxy potentials 3 state line system of

human body, which are expressed in predominating of any one of three basic state

i.e. in "Badgan" persons has been dominated the betta - state of MS (more energy -

syntethizing)with high reduction activity within all organism's membrane - redoxy

potentials 3 state line system which conditioned more preservation of free energy (F)

in the form of ATP, NADPH and fats in the third compartment of human body with

less dispersion of heat energy /Q, TS/, /B.P.Skulachev 1987, D.Nikols 1985/.

THE MEMBRANE MECHANISM OF CONSTITUTION DIFFERENCE OF

INDIVIDUALS

While in energy synthetizing membrane structure of "Mkhris" dominated individuals in

connection with prevailing of a - state of MS with high oxidation activity within all

organism's membrane-redoxy potentials 3 state line system created

precondition of more transition of electrochemical gradient /H2+/ to "heat energy" /Q/

with middle synthesis of high energy phosphate as ATP, high energy electrons as

NADPH because of "high proton leak and proton conductance" /Y.A.Bladimirov/.

Basing on such theoretical explanation we suggested the new principle of prevention

and treatment of obesity, which matter lies in transferring of betta - state of MS with

high reduction activity to alpha state of MS with high oxidation activity by forming of

"artifical" protonophore phore i.e transferring the "Badgan" coded people to the

"Mkhris" coded people. . .1989, Y.M.Lopuchin 1983, B.P.Skulachev 1987/.

Prevailance of gamma - state of MS /intermediate, unstable/ leads to less

energyaccumulating, energysynthetizing and low thermogenic activity, which are

expressed by thermins of nature of "rlung" coded people.




87

The results of our investigations

A. In the result of comparative investigation conducted in many groups of people we

are revealed that first group of people are distinguished by 1.3 fold increase of

external patterns of general characteristics of Mkhris type coded constition in

comparision to second group people of Badgan type coded constition such as:fast

pulse, hot feeling in the body surface, heat of the body (<36.8°C), much vapour,

perspirations, intolerable in hot place and hot room, desire for only cold place and

food. Body temperature (TS) of this group of people, was high by + Q.7-0.9°C

(36.8°C) than second group of people. In connection with this body weight (F) was

1.8 fold low than second group of people (SGP) and also low gaining of weight in the

background of good appetite and great thirst, little sleep at night anxious.

Basing in obtained result we are regarded that people of first group are more similar

to Mfthris - dominating individuals according to theory of Tibetan Medic ine.

Besides, biochemical and biophysical studies shows that first group of people i.e

Mkhris dominating coded people are characterized by low level of resistance

membrane structure to lipid pereoxidation damage effect and the low Ch: LPOP ratio

and high contents of lipid Pereoxidation, deprotonized products such as MDA, DK,

shiff Base in membrane structures within all organism's membrane - redoxy


In first group of people the resistance of MS within all organism's membrane - redoxy

potentials 3 state line system to damage effect of H2O2 was 1.3 fold low than SGP,

the ratio Chr.LPOP was 1.4 fold less than SGP, while the quantity of MDA, Shiff

base, DK in membrane structures were 1.32 fold high than SGP, respectively.

In such way, results of our investigation shows that first group of people i.e Mkhris

dominating coded people with high percentage of Mkhris constition type are

distinquised by prevailence of fluid alpha state with high oxidation activity within

whole organism's membrane structures.

Also we are revealed that in people dominatly coded by Mkhris abstract thermin

between body temperature and Ch: LPOP ratio existed negative correlation (r =

0.97), between body weight and Ch: LPOP ratio r = + 0.89 correlation, between body

temperature and LPOP products r = + 0.78 correlation, between body temperature

and permeability of MS + 0.88 correlation, between body weight and permeability of

MS - 0.93 correlation. The existence of such close correlations demonstrated that in

people dominatly coded by Mkhris abstract thermin the increase of fluid alpha

state of MS, increase of lipid pereoxidation products and permeability of MS

(decrease of Ch: LPOP ratio) leads to increase of body temperature (TS) and

decrease of body weight F).

Comparative analysis gives the possibilty to reveal that the second group of people is

characterized by 1.8 fold increasing of external patterns of general characteristics of

abstract Badgan type constitution than Mkhris abstract code dominated first group of

people (FGP), such as: slow pulse, constant coldness of the body (>35.5°C), low




88

bodily heat, physical mental heaviness, poor appetite, weak digestion, rapid gaining

of weight (obesity), unclear awareness, abundance of Mucus, much sleep et all.

Body temperature of this group of people was low by 1.3°C, body weight was high by

10-20 kg than first group of people.

Our data demonstrated that second group of people are more similar to individuals,

who according to theory of Traditional Medicine belongs to so called " abstract

badgan-dominating people". Also, data, obtained by experimental works revealed

that people of second group arc characterized by low concentration of lipid

pereoxidation products. In second group of people the resistance of membrane

structures to prooxidant effect of H2O2, was 1.3 fold high than FGP and the quantity

of lipid pereoxidation products (Dien konjugat, MDA, Shiff Base) were 1.4 fold lower

than FGP. In such way the results of our investigation revealed that in Badgan

dominating second group of people is prevailed the solid betta state of MS within all

organism's membrane - redoxy potentials 3 state line system.

Also, we are finding out the positive strong correlation between increase of body

weight and increase of resistance of MS within all organism's membrane - redoxy

potentials 3 state line system to prooxidant damaging factors (r = + 0.9), between

body weight and Ch: LPOP ratio (r = + 0.9), negative correlation between body

temperature and resistance of MS (r = - 0.89), between body temperature and Ch:

LPOP ratio (r = - 0.96). In second group of people (abstract badgan dominated

people).

In the result of establishing such strong positive and negative correlation between

some biochemical and biophysical parameters in abstract Badgan dominated people

we came to conclusion that decreasing the membrane permeability and lipid

pereoxidation products and increasing Ch: LPOP ratio in whole organism's

membrane structures accompanied with increase of free energy (body weight - ATP

synthesis - F) and decrease of enthropy TS-body temperature - heat emission.

This suggestion confirmed by results of our investigation, when we revealed the

addition of weight on 1.36 fold (<0.05) on animals with administration of cholesterol

(betta - state of MS) in doze 250mg/kg . Much sleep, physical and mental heaviness

of abstract Badgan-dominated people may be explained by slow depolarization

process of MS of excitable cells owing to prevailance of Betta state of membranes.

The above mentioned obtained results gives to us the possibility to explain the theory

of MTM on constitional type of people from view point of thermodynamic laws in

membrane levels within all organism's membrane - redoxy potentials 3 state line

system. In the theory of Oriental Traditional medicine it was stressed that. . . if Mkhris

existed in equal forms, which forms the "heat" of organism, it provides the nutritions

and substrates necessary to function of all organism. . . if Badgan is existed in equal

state which adds the weight and fat, protects the losses of substrates, ensuring the

longevity of life.




89

Basing in the results of our investigation we came to conclusion that such formulation

on whole organism's regulatory function of abstractized rlung, Mkhris Badgan is

closely connected with thermodynamic process, which constantly takes place in living

organism within all organism's membrane - redoxy potentials 3 state line

system. (M.Ambaga, B.Sarantsetseg 1990).

In such way, in thermodynamical system, where is prevailed - alpha state of MS with

high oxidation activity the thermodynamic process is going in direction to more

losses or usefull free energy (F), and to more dispersion of useless "heat" energy,

which by otur investigaton are observed in abstract Mkhris dominated people i.e.

thermodynamic process of transition F-TS is directed to decrease of F, and to

gradually increase of /TS/, which proably may serve the guidelines of right

interpretation of theory Traditional medicine : as "Mkhris forms the heat energy. But

excessively increase of Mkhris burnes all the energy and nutrients of all organism

…". This is reason, why abstractized Mkhris dominated people are distinguished by

hot surface of Body, low gaining of weight in background of good appetite and great

thirst. Besides, prevailance of alpha fluid state of MS in the excitable cells of central

nervous system in abstract Mkhris dominated people leads to rapid depolarization

and increasing the excitability ol neurons by which may be explained the bad sleep,

anxious, observed in this type of people. While betta -state of MS of organism

creates more stabile "themodynamic system, which is due to trans-configuration of

saturated fatty acids and cholestrol /L.Streir 1985/. In such system, the

thermodynamic process is accompanied by more reservation of free energy /F-ATP

synthesis , energy accumulation/ and less dispersion of heat /Q,TS/ energy i.e.

thermodynamic reaction proceeds in direction: to gradualy increase F and to

decrease of Q, which are expressed in Traditional Medicine as … Badgan addes the

weight of organism, decreases the heat energy, protects the substrates and gives

possibility to long life . . .

This is reason, why in abstract badgan dominated people, who distinguished by high

level of betta state of membrane structure observed the following external patterns

such as: low bodily heat and rapid gaining of weight /obesity/.

Basing on such explanation we suggested /M.Ambaga 1996/ the new principle of

prevention and treatment of obesity, matter of which lies in transferring of betta -state

of MS with high reduction activity to a - state of MS with high oxidation activity i.e by

forming the regulated "artifcial" protonophore configuration on solid state of MS

through which could be lossed the excessibly free energy /F/ in the form of

dispersion of heat energy /Q/, and limited the excessive energy accumulation of free

energy in the form of ATP, NADPH synthesis .




90

To question of obtaining the antiageing preparation in the theoretical basis of

Traditional Medicine and all organism's membrane-redoxy potentials 3 state

line system.

First of all, we have the purposes to explain the theoretical and phillosophical

essence of the theory of TMTM, in which the "human age", "the human ageing

process","old age" has been expressed as "in the young age - prevailed badgan

(water, earth element) ", "in the middle age-dominated Mkhris (fire element)", "in the

old age- prevailed rlung /rlung element".

According to the notions of Traditional Medicine". . .those of middle age are "Mkhris"

people, in such age the clarity of the senses, complexion and strength are increased

and heightened bodily heat, courage and intelligence . . .Young people are "badgan"

people and in same age bodily constituents are increased . . . People advanced in

age are "rlung people", when the clarity of the senses decreased and physical activity

worsened".

Scientific interpretion of above mentioned theoretical expression of Traditional

Medicine could be easily made in the framework of our new conception "rlung,

Mkhris, Badgan - all organism's membrane - redoxy potentials 3 state line

system.

The results of foreign scientist's investigation (B.B.Frolikis 1986, Yu.M.Lopukhin et all

1983, A.Alesenko 1983) surely showed that all organism's membrane structures

have been subjected to natural consistent, consequent changes as: betta state with

high accumulative, reduction activity —> alpha state with oxidation,

thermogenic activity —> gamma state with low redoxy potential based

accumulative, reduction and oxidation activity during ontogenetic development of

human organism, bringing the more specifical feature of every groups (young -

middle - old).

In young age accumulated more quantity of sphingomyelin and cholesterol (betta -

state of MS) in membrane structure (MS) of all organisms, which served as a role of

signals to increase the activity of DNA, PNA-polimerase, and mitotic activity of cells

(Yu.M.Lopukhin et all 1983, B.M.Dilman 1981, V.M.Babenko 1991), which expressed

in MTM by following thermins: ". . . in young age prevailes "Badgan" which ensures

the maturity of body. . . ".

In middle age on whole organism's membrane structure predominated alpha - state

of MS (unsaturated fatty acids) by enzymatic and endocrinic mechanisms

(L.N.Bogatskaj 1990, N.M.Babenko 1991), which creates the precondition of more

activation of all membrane binding enzymes such as: adenylatcyclase, cyclic AMP,

Na +, K +, Ca + -ATP-ase and many all receptors (D.F.Chebotarev 1990).

Such changes of all organism's membrane - redoxy potentials 3 state line

system, which occured in human middle age served the reason of appearance of




91

Traditional medicine's theory ". . . middle age, when Mkhris is dominated, strength

and complexion of organism are increased . . . ".

In duration of ageing in MS of all organisms is increased the intensity of process of

lipid free radical pereoxidation (with involvement of unsaturated fatty acids) of a-state

of MS and exhausted antioxidants supplies, which is accompanied with replacing of

alpha state of MS with oxidation, thermogenic activity by gamma state of MS with

low redoxy potential based accumulative, reduction and oxidation activity.

Such ageing changes within all organism's membrane - redoxy potentials 3 state

line system leads to decrease the activity of whole organism's enzymes and

thermogenic, metobolic activity of MS (Y.M.Lopukhin 1983, D.P.Chebotarev 1990).

This is concided with the notion of TM ..." in old age the energy, strength and activity

of organism are exhausted. . . ". In such way the theory of TM on the ageing process

can be express in the framework of the new conception "rlung, mkhris, badgan -

membrane structures " as" young age – Badgan – p - state of MS", "middle age –

Mkhris – a - state of MS", " old age – rlung – y - state of MS". In the result of such

explanation of theory of MTM on age depending changes Badgan – Mkhris - rlung

according to our new suggestion of " rlung, Mkhris, Badgan – membrane - redoxy

potentials 3 state line system", we suggested the new principle of prevention of

early ageing process, which essence of directed to protection of fluid a - state of all

organism's MS from lipid pereoxidation process by using "unsaturated fatty

acids+antioxidants" and removing the toxic lipid pereoxidation products and limiting

the peredominance of gamma state of MS with low redoxy potential based

accumulative, reduction and oxidation activity i.e by prevention of transferring the

abstract mkhris - coded middle age to the abstract rlung coded old age .

The experimental investigation, conducted by us shows that the new antiageing

preparation obtained from some plants, used in TM is increased the life duration of

experimental animals by inhibition of lipid pereoxidation process.

THE THEORY OF TIBETAN-MONGOLIAN TRADITIONAL MEDICINE ON THE

TASTE, POWER, QUALITY OF MEDICAMENTS

The reason why the scientic basis of theory Traditional Medicine on taste ,power,

quality of medicaments should be explained in the level of membrane - redoxy

potential 3 state line dependent systems as 4 compartments and 10 functional

systems comprising all 14 trillion cells of human body, it is connected with these

facts that there are not really existed a human species as ―Homo sapiens plus

rlung, mkhris, badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus

yan, yin‖ as if containing the 14 trillion living rlung, mkhris, badgan, yin, yanalong

with 14 trillion living cells only postulated by Traditional medicine doctors, all their

diagnostic and treatment methods based in this form of human specie, but

categorically resisted, refused by NCM medicine.




92

One of many interesting theoretical problems of TMTM, which philosophical and

scientific essence can be interpreted in the framework of the new conception "rlung,

Mkhris, Badgan – membrane - redoxy potentials 3 state line system "is the theory

about taste, power, quality of Medicaments. In this connection we are putting the

goals to clarify the following questions:

1. What are taste, power, quality of Medicaments, how understand these specific

thermins and notions of Traditional Medicine from viewpoint of Recent Biology and

Medicine.

2. What kinds of difference and similarity are existed in the theoretical notions of

Traditional Medicine and Recent Medicine in regarding to the structure, action, usage

of some Medicaments.

What are taste, power, quality of medicaments

Despite in the Universe there are many medicaments of plant, animal, mineral origin,

and medicinal raw materials, which number would be estimated (counted) by several

thousands, the latter according to theory of TM in generally classified in to 6 tastes:

as sweet, sour, salty, bitter, hot and astringent and divided to 8 power: as heaviness,

oiliness, coolness, softening, lightness, roughness, heat, acridity, to 17 qualities as:

gentleness, heaviness, warmth, oiliness, firmness, coolness, softening, coldness,

pliability, fluids, dryness, fatlessness, heat, lightness, acridity, roughness, motility.

Besides, in generally all Medicaments of various origin classified in to three many

groups as "rlung regulating", "Mkhris regulating", "Badgan regulating".

The medicinal plants, animals, minerals, which have had the sweet, sour, salty, hot

tastes formed by combination of two elements as "sweet taste = earth + water

elements", "sour taste = earth + fire elements", "salty taste = fire + water elements",

"hot taste ̂fire + air (rlung) elements" possessed the activity to decrease "rlung" i.e

the heavy, firm (strong), oily, hot quality of "earth", "fire" elements had exerted the

action to decrease (inhibit) the light, motile, cool, strong characteristics of "rlung".




93

Picture № 10

The membrane –redoxy potential 3 state mechanism of the theory of TMTM on

taste, power, quality of Medicaments

Medicaments, possessing bitter (water + air), sweet (water + earth), astringent (earth

+ air) tastes exhibited the activity to decrease the general characteristics of "Mkhris",

which theoretical basis had been explained by these lawfull rules that cold, stupid,

heavy, fluid, unoily quality of earth and water elements exerted the action to

decrease the hot, acrid, oilly, light general characteristics of Mkhris. Meanwhile,

medicaments of plant, animal and minerals origin, possessing the hot (fire + air),

salty (fire + water), sour (fire + earth) tastes had possibilty to decrease the "Badgan",

The universe

Healthy human body Medicament

s

External signs

Taste

External signs

The balance of

general

characteristics of

rlung, Mkhris,

badgan

Disease

External signs

The appearance of quality of

medicaments by normalisation of general characteristics of rlung, mkhris, badgan associated with normalisation in membrane-redoxy 3 state system.

External signs

The appearance of quality of

medicaments by

normalisation of general characteristics of rlung,

mkhris, badgan associated

with normalisation in membrane-redoxy 3 state system.

The interaction betw een

five elements of medicaments and human

body

Pow er of

medicaments The disturbance of balance betw een 5

elements inside human

body

Fire element

Rlung element

Rlung element

Earth element

Water element




94

because the hot, acrid, light, rough quality of "fire" element had exhibited the action to

decrease the cold, stupid, heavy, smooth general characteristics of the "Badgan".

From all above mentioned, it would be clear that the general characteristics of the

rlung, Badgan and Mkhris and the quality, power of medicaments has been appeared

in the level of similar, unique matcriall substances existing inside of human body i.e

the quality of medicaments appeared outside of human body as change of general

characteristics of rlung, Mkhris, Badgan.

What is taste of Medicaments

In the result of conducting the comparative theoretical analysis by using the new

methodological approach "substance - external properties - abstraction" we came to

conclusion that "taste of medicaments" is abstract notion, which demonstrated the

existence (availability) of concrete chemical structure in Medicaments of various

origin (plant, animal, minerals), which after binding, acting (interaction) with

biomolecules, bioreceptors existed in plasmic membranes of cells of human body

can cause the specific biologocal effect, action. The notion of "power of

medicaments" of TM means the specific interaction between of five elements existing

inside of human body and five elements, contained in Medicinal plants, animals,

minerals, i.e according to theory of Recent Biology and Medicine the notion of power

of Medicaments shows the interaction between concrete chemical structures of

medicaments and specific chemical structure of Bioreceptors, biomolecules,

enzymes, located in plasmic membranes inside of human body (Picture N1 1) .

Meanwhile, the notion "quality of Medicaments" demonstrated how externally

appeared the interaction occurred between five elements of medicaments and five

elements of human, body (interaction between chemical structure of medicaments

and bioreceptors chemical structure according to the theory of Recent Biology

occurred in molecular, submolecular levels inside of human body) through change of

general characteristics of rlung, Mkhris, Badgan i.e according to the theory of Recent

Biology and Medicine the notion "quality of medicaments" shows, how appeared the

normalisation of pathologically changed signs of Disease in the result of "substance-

receptor" interaction, occurred inside of human body.

In the otherwise, can be say that it is not possible to directly recognize the "power" of

medicaments outside of human body, only we have possibility to reveal this through

the appearance of quality of medicaments and through the change of general

characteristics of rlung, Mkhris, Badgan.

In such way if apply the new methodological approach "Substance -> external

patterns - abstraction" in the comparative study of theoretical expressions of TMTM

on the taste, power, quality of medicaments it was became clear that the taste,

power, quality of Medicaments are various sites of one process, which occurred

around the one "essence" i.e the notion "taste" demonstrated the existence of

concrete chemical structure in medicaments, possessing the activity to interact with




95

bioreceptors and cause the pharmacological effect, while the notion "power of

medicaments" shows the interaction of chemical structures of medicaments with

bioreceptors, causing the specific pharmacological effect inside of human body in the

level of hidden material, biological substance, the notion "quality of Medicaments"

exhibits that how such pharmacological effect, carried out in hidden, secretly,

substance level inside of human body externally appeared outside human body as

change of "external patterns" of rlung, Mkhris, Badgan.

In this connection raised the question - what kind of hidden, materiall, biological

substance conditioned the appearance of the notion of "power and quality of

medicaments" (Picture N 11).

How shows the abovementioned theoretical comparative analysis, the this biological

substance, which conditioned the appearance of general charactcristucs of rlung,

Mkhris, Badgan, simultaneously, should be the structure, where carried out the

process,leading to the appearance of the notion "quality" and "power of

medicaments".

In the result of conducting the comparative theoretical investigation by using the new

conception "rlung, mkhris badgan - membrane - redoxy potentials 3 state line

system" we are revealed that the membrane structure, their basic three states (alpha

state with high oxidation activity, betta state with high reduction activity, gamma

state with low reduction, oxidation activity) can be play the role of such Material,

Biological substance, which1 leads to appearance of general characteristics of rlung,

Mkhris, Badgan and also, conditioned the appearance of notion about "power",

"quality" of medicinal plants, animals, minerals.

THE PULSEDIAGNOSTIC METHOD OF ORIENTAL MEDICINE AND MEMBRANE-

REDOXY POTENTIALS 3 STATE LINE SYSTEM OF 14 TRILLION CELLS

The reason why the scientic basis of the pulsediagnostic method of theory

Traditional Medicine should be explained in the level of membrane - redoxy potential

3 state line dependent systems as 4 compartments and 10 functional systems








Pulsediagnosis is more important, because it in somr concrete case clearly shows

the type of disease present in the human body, but in order to maintain a calm and




96

continuous nondisturbed harmony of the rlung, mkhris, Badgan, the most attention

should be paid to time, place, precondition of conducting the pulsediagnostic method.

Observances to be followed by the patient so that pulse can be ascertained.

A.Intake of overly nutrititions food such as meat or wine should be eliminated on the

day or prior to pulse reading.

B.No overeating

C.No fasting

D.No sexual intercourse

E.No sleeplessness, no overtalking No observance of the above criteria may result in

confusion.

The pulse reading is to be performed in the early morning

In the famous books, writting by Darmu naaramba Luvsanchoidog (1690) had been

emphasized the time for taking of the pulse as, when "the sun has risen but the rays

have not fallen on the mountain top".

It is pre-dawn, when warm breath is neither exhaled in large quantity nor is cold air

inhaled. If the pulse taken before this time stage the power of the moon (cooling or

yin) is stronger and the pulse is mistaken for rlung and Badgan (ph legm). If pulse

taken after this stage the heat of the sun (hot and yang) will make the pulse appear

like a Mkhris (hot, blood) disorder (Yeshe Donden 1980).

In this connection, has been raised the question, what kind of hidden, materiall,

biological substance, existing inside human body conditioned the really external

appearances of pulse and influenced by abovementioned psychological, behavorial

factors and "day-night shift", food, which oftenly leads to distort the right, really

appearance of pulse.

By using the new methdological approach "Substance - external -» patterns ->

Abstraction " we proposed that this kind of Material substances should be possess

the following attributes (attribute quality):

1. It influenced by human constitution type, food, age, emotion, circiad biorhytm, hot -

cold temperature, all these leads to appearance either Mkhris, or rlung, badgan

character of pulse.

2. 1t exerted the direct effect (influence) on the regulation of proton leak, proton

conductance speed, donators utilization, acceptor delivery symphatic -

parasymaphatic nervous system, adreno - cholinoreceptors, activity of

adenylatcylclase - cholinoesterase enzymes activity within all organism's

membrane - redoxy potentials 3 state line system, actin - myosin interaction, Na,

K, Ca ion channels of smooth muscles of vessels wall, aggregation - desaggregation

system, blood viscosity and fluidity, which in Recent Biology and Medical science

considered as main factors of pulse regulation.

Our new conception "rlung, Mkhris, Badgan - membrane - redoxy potentials 3

state line system" gives the possibility to say that the membrane - redoxy

potentials 3 state line, localized in the membrane structure of smooth muscles




97

cells (SMC) of vessel wall and cardiomyocytes can be play the role of such material,

biological substances, because it possessed the above mentioned attributes.

Besides, it may be that the before pre - dawn increase of solid betta state of

membrane structure with high reduction activity according to normal circaid

biorhytm leads to activation of parasymphatic nervous system - cholinoreceptors and

appearance of cold-badgan character of pulse, while the after predawn increase of

fluid alpha state of MS with high oxidation activity normal circaid biorhythm is

accompanied with activation of symphatic nervous system adrenoreceptors and

appearance of Hot-Mkhris character of pulse.

Picture №11

The theory of

1. (α+γ+β) – The normal level of Basic

three states of membrane-redoxy 3 state system. 2. (β1+ β2+ β3+ β4) – The basic points of

the occurrence of solid phase transition in membrane-redoxy 3 state system.

3. (α1+ α2+ α3+ α4) – The basic points of the occurrence of fluid phase transition in membrane-redoxy 3 state system.

4. (6, 7, 8, 9) – The appearance of various variants of Hot pulse 5. (4, 3, 2, 1) – The appearance of various

variants of Cold pulse 6. (5) – The appearance of healthy pulse

Ratio of saturated:

unsaturated fatty acids (%)

The relationship between the solid-fluid phase transition in membrane-

redoxy 3 state system.

and the normal, pathological pulse appearance




98

Mongolian Traditional Medicine on the hot and Cold character of pulse and

membrane-redoxy potentials 3 state line system

It should be emphasize that the secrecy (art) of establishing the right diagnosis laid to

differentiate the three types of pulse as "healthy", "hot pathological", "cold

pathological". The pulse in health and disease can be determined by the rate, nature

and volume of the pulse. In general the normal pulse rate is 5 times for each

respiratory cycle. During inhalation, earth and water pulse beats twice. In between

inhalation and exhalation on pulse beat from metal element ensues. Exhalation

incorporates pulse beat from the fire and wood elements.

In general if there is greater than 5 beats per respiratory cycle this disorder is termed

a hot disorder. More specifically, in hot disorder, 6 pulse beats per respiratory circle

denote a minor hot (fever), 7 to 8 a moderate hot (fever) and 9 or more (over coming

the hot high points). If there are less than 5 beats per respiratory circle, the disorder

is termed cold. In a cold disorder 4 pulse beats per respiratory cycles denote a minor

cold illness. 2 to 3 denote a moderate cold disease and 1 or less (over coming the

cold low points) denotes a severe disorder.

In the framework of the new conception "rlung, Mkhris, Badgan - membrane - redoxy

potential 3 state line system has been established that the scientific essence of

distinguishing the healthy and cold, hot pathological pulses by conducting the pulse

diagnostic methods can be explained by maintenance of normal equilibrium

(balance) between alpha, betta, gamma states of MS and also induction of liquid-

fluid phase transition in the MS with high reduction activity and solid phase

transition in the MS with high reduction activity under pathological factors.

The relationship between the solid-fluid phase transition in MS and the normal,

pathological pulse appearance

In the healthy person has been established the balanced equilibrium between alpha,

betta, gamma states of membrane structure and in such way, inhibited the excessive

pathological increase and decrease of three basic states by "alpha - betta - gamma"

membrane state based mechanism which accompanied with normalization of the

activity of membrane binding receptors, enzymes, hormones, symphatic -

parasymphatic nervous system, adreno - cholinoreceptor activity, all the these

processes resulted to externally appearance of healthy normal pulse signs.

It was interesting that how shown in the picture N 13 under figure (5), "(betta " points

of MS may be expressed in the theory of MTM as "inhalation - cold air - solid state of

MS - earth, water pulse beats", "gamma" point of MS determined in the theory of

MTM as "between inhalation and iexhalation - Normal temperature air-metal pulse




99

beats", "alpha " points of MS expressed in the theory of MTM as "exhalation - hot air -

fluid state of MS - fire, wood elements pulse beats".

But can be say that in Mkhris dominated persons, age, in Mkhris increased summer

season, using Medicaments, foods which contributed to increase the general

characteristics of Mkhris has been induced the fluid phase transition of MS by

following subsequent points showed in figure as 6. 7. 8. 9.

The such fluidphase transition, occurred in membrane structures accompanied with

abruptly increase of activity of Adenylatcyclase enzyme, adrenoreceptors, pulse

beating Rate, pulse tension, which externally characterized as minor hot, hot,

moderate hot, overcoming the hot boundary pulses i.e. 6 point of fluid phase

transition corresponds to hot pulse, 7 point corresponds to minor hot pulse, 8 point to

moderate hot pulse, 9 point - to exclusive hot pulse (overcoming the hot boundary). It

should be say that 6, 7, 8 points of alpha fluid phase transition of MS would taken

place in the frame of normal adaptive reaction, but reaching the fluid phase transition

in 9-point of MS leads to irreversible membrane fluidization, resulting to sharply loss

of activity of all the membrane binding receptors enzymes, biological active

compounds, at last to death.

The membrane - redoxy potential lever mechanism of appearance of normal

healthy pulse in spring season according to clockwise rules

Picture № 12

Normal clockwise

“rules”

The appearance of specific for

liver pulse as taut, fast

Increase of resistance of MS to action of pathogenic factors

Stabilization of MS of hepatocytes

The lever mechanism of the betta state of membrane –

redoxy potential 3 state system

Increase of viscosity of MS of lung cells

Decrease of adrenoreceptor’s activity and oxygen

di ffusion

Comparative inhibition of functional activity of

lung

The limitation of appearance specific for lung pulse as sharply, rough




100

Concretely speaking can be say that:

1. 6 pulse beats per respiratory circle denote a minor hot (fever) corresponds to

about 10 - 15 % increase of alpha state - increase of oxidation reaction speed -

increase of proton conductance - increase of proton leak- increase of acceptor

delivery with following increase of donator utilization - increase of metabolism rate -

increase of pulse frequency - increase of arteial pressure - increase of breathing

frequency - increase of proton gradient expenditure to heat formation , all these

occurred within all organism's membrane - redoxy potentials 3 state line system,

2. 7 to 8 a moderate hot (fever) and 9 or more (over coming the hot high points)

pulse beats per respiratory circle denote a minor hot (fever) corresponds to about

20-25 % increase of alpha state - increase of oxidation reaction speed - increase of

proton conductance - increase of proton leak - increase of acceptor delivery - with

following increase of donator utilization - increase of metabolism rate- increase of

pulse frequency - increase of arteial pressure - increase of breathing frequency -

increase of proton gradient expenditure to heat formation, all these occurred within

all organism's membrane - redoxy potentials 3 state line system,

3. 9 or more (over coming the hot high points) pulse beats per respiratory circle

denote a minor hot (fever) corresponds to about 30-35 % increase of alpha state -

increase of oxidation reaction speed - increase of proton conductance - increase of

proton leak - increase of acceptor delivery - with following increase of donator

utilization - increase of metabolism rate - increase of pulse frequency - increase of

arteial pressure- increase of breathing frequency - increase of proton gradient

expenditure to heat formation, all these occurred within all organism's membrane -

redoxy potentials 3 state line system,

Contrary to this, in Badgan - dominated person, age (spring) and excessive using the

medicaments, foods, possessing Cold, heavy, stupid, oily property, power, quality

resulted to occurrence of solid phase transition of MS by following subsequent points

as 4, 3, 2, 1 (figure N 13).

The solid phase transition, occurred in MS Leads to suddenly activation of

acetylcholinesterase, cholinoreceptors and decrease of pulse tension, pulse beating

Rate, which externally characterized as minor cold, cold, moderate cold, excessive

cold (over coming the cold boundary) pulses.

During our comparative theoretical analysis it was became clear that 4, 3, 2 points of

solid phase transition (SPT) would be carried out in the frame of Normal adaptive

response reaction, but SPT occurred in 1 point had accompanied with completely

solidization of MS, the latter leads to abruptly increase of viscosity of membrane

structures and inactivation of all membrane binding enzymes, receptors, resulting

sometimes to death of patients.

It may be say that:

1. 4 pulse beats per respiratory cycles denote a minor cold illness corresponds to

about 10-15 % decrease of alpha state - increase of betta state of MS - decrease of




101

oxidation reaction speed - decrease of proton conductance - increase of proton leak-

decrease of acceptor delivery - with following decrease of donator utilization-

decrease of metabolism rate - increase of pulse frequency - decrease of arteial

pressure - decrease of breathing frequency - decrease of proton gradient expenditure

to heat formation, all these occurred within all organism's membrane - redoxy


2. 2 to 3 denote a moderate cold disease corresponds to about 10 - 15 % decrease

of alpha state - increase of betta state of MS - decrease of oxidation reaction speed -

decrease of proton conductance-increase of proton leak - decrease of acceptor

delivery - with following decrease of donator utilization - decrease of metabolism rate

- increase of pulse frequency - decrease of arteial pressure - decrease of breathing

frequency - decrease of proton gradient expenditure to heat formation, all these

occurred within all organism's membrane-redoxy potentials 3 state line system.

3. 1 or less (over coming the cold low points) denotes a severe disorder corresponds

to about 10 -15 % decrease of alpha state - increase of betta state of MS - decrease

of oxidation reaction speed - decrease of proton conductance - increase of proton

leak - decrease of acceptor delivery - with following decrease of donator utilization -

decrease of metabolism rate - increase of pulse frequency - decrease of arteial

pressure - decrease of breathing frequency - decrease of proton gradient expenditure

to heat formation, all these occurred within all organism's membrane - redoxy


Our suggestion, regarding to the existence of close coincidence as "alpha state of

MS - hot character of pulse" has been confirmed by results of our joint investigation,

during which we are established thai in Mkhris - dominated persons the increase of

fluid state of MS (as increase of lipid pereoxidation products: cholesterol ratio) leads

to appearance of hot pulse as: increase of pulse beating rate, systolic arterial

pressure, and vessels peripheral resistance, while in Badgan - dominated persons

the prevalence of solid betta state of MS (as decrease of lipid pereoxidation products:

cholesterol ratio) are accompanied with manifestation of cold character of pulse as:

decrease of pulse beating rate, systolic arterial pressure and vessels peripheral

resistance (M.Ambaga, Sh.Bold, B.Saranstetseg 1998).

The membrane - redoxy potentials 3 state line system based mechanism of

Season depending change of pulse character The normal pulse appearance in

spring season

During spring the wood element is most influential and liver pulse becomes most

active so a normal pulse becomes under the influence of the liver or wood element,

which characterized as tense, taut or fast during the spring time. If during this spring

the pulse of spleen, kidney, heart (friend, mother, son of wood element) arc also

found to be taut and fast the disease of patients easily subjected to recovery.




102

Meanwhile the enemy of wood element is metal, which is associated with the lung, if

in the spring the lung pulse is not strong and not gives own character of pulse, his

mission will be successful.


normal pulse appearance (NPA) in spring season

Season depending increase of betta solid state in the whole organism's membrane

structure in spring season leads to decrease of excessive damage of MS of

hepatocytes by betta -» alpha mechanism, resulting to appearance of specific for

liver pulse as: tense and taut, fast.

Simultaneously, increase of betta state of MS in whole organisms level in spring

season is accompanied with increase of solid betta state in lung cells membrane

structure, resulting to activation of adrenoreceptors, bronchospasm, increase of

tension of Bronchial smooth muscles, decrease of Surfactant synthesis and oxygen

diffusion, which at last leads to depression of specific for lung pulse as sharply. rough

(Picture N 14).

In such way, the lung cells functional activity, oxygen diffusion, generation of toxic

oxygen active forms (O'2, HO', O) in spring under influence of dominated in this time

betta state of MS has been limited, prevented the damage of hepatocytes MS by lipid

pereoxidation mechanism i. e limited the dangerous effect from enemy organ-lung to

liver, which expressed in the theory of Traditional Medicine as "friend-enemy"

relationship between lung and liver in spring time.




103

The disturbance of normal membrane-redoxy potential 3 state “lever”

mechanism of appearance of healthy pulse in spring season

Picture № 13

The disturbance of normal pulse appearance (DNPA) in spring season

According to the theory of Tibetan-Mongolian Traditional Medicine "... If the lung

pulse is found to be taunt and fast in spring time the patient, who exhibits this pulse

will face disease because is occurred the antagonism from enemy organ-lung to liver

organ".


DNPA in spring season

If in the spring season disturbed the "lever" mechanism of whole organisms solid

betta state of membrane structures, which acted by ―clock-wise‖ rules, how shown in

the picture N10, by which the solid, betta state of MS is exerted the limitation effect in

attitude to lung cells and to appearance of specific for lung pulse as sharpy, rough i.e

the disturbance of regulatory function of betta state of MSin the spring season, the

defect of ―lever‖ mechanism of Betta state, appeared in the from of ―counter

clockwise‖ rules leads to decrease of the activation of adrenoreceptors, excessive

Pathological ―counter‖ clockwise

rules The disturbance of lever mechanism of betta

state and red potentials in membrane-redoxy

potential 3 state system because of deficiency

of Antioxidant system and pathological increase

of alpha state of membrane structure

The damage of MS of

hepatocytes by lipid

pereoxidation mechanism

The disturbance of Normal

pulse appearance of liver

The appearance specific

for lung pulse as sharply,

rough

Excessive formation of

oxygen reactive radicals

in lung cell membrane

Decrease of

Adrenoreceptor’s activity

in lung cell membrane




104

oxygen diffusion and generation of toxic oxygen active forms (O2, O, H2O2, HO)

within membrane-redoxy potentials 3 state line system, existed in lung, which is

accompanied with intensive damage of cell membranes of hepatocytes and

exhaustion of antioxdant defensive system: all these processes may be expressed in

the theory of Tibetion-Mongolian Traditional Medicine as: ― . . .if in the spring had

been appeared specific for lung pulse as sharply, rough is created the precondition

of provocation of liver disease‖ (Picture N 15).

The normal pulse appearance in autumn season

During autumn the metal element is most influential, Lung reverals his specific pulse

as sharply, rough. In this connection, his mother organ-spleen gives smooth, short

puls, son organ-kidney gives slow, smooth character of pulse, friend organ-liver

shows thin, intense pulse, and his enemy organ-heart not exhibits specific for him

pulse as thick, long: these all has demonstrated that human body is existed in the

normal healthy state.


NPA in autumn season

The season depending increase of fluid alpha state of MS in whole organisms

membrane-redoxy potentials 3 state line system playing the role of ―lever‖

mechanism in autumn time is resulted to decrease of viscosity of MS of lung cells,

activation of adrenoreceptors, increase of surfactant synthesis and oxygen diffusion,

which are externally leaded to the appearance of specific for lung pulses as: sharply

and rough (Picture № 14)




105

THE NORMAL PULSE APPEARANCE IN AUTUMN SEASON BY “LEVER”

MECHANISM DUE TO FLUID

ALPHA STATE AND OXY POTENTIALS OF MEMRANE-REDOXY 3 STATE

SYSTEM

Picture 14

The disturbance of NPA in autumn season

Judging by the theory of TMTM… in autumn time, if the heart pulse is found to be

thick and long, the patient, who exhibits this pulse will face disease because is

occurred the antagonism from enemy organ-heart to organ-lung.

The membrane-redoxy potentials 3 state line system based mechanism of

DNPA in autumn season

If in the autumn time, has been disturbed the "lever" mechanism of whole organisms

fluid alpha state of MS and antioxidation defense system, by which ensured the

normal morpho - functional relationship between lung and heart (enemy organ to

lung) according to "clock wise" rules, all these processes are resulted to loss of the

normal excitability - contractility of heart cells i.e excessive excitability of

cardyomyocytes has been accompanied with increase of detergent toxic lipid

The “lever” mechanism of f luid alpha state and oxy

potentials in the membrane-redoxy 3 state line systemc

system

of Membrane structure

Normal clockwise “rules”

The appearance of specific for lung pulse as sharpy, rough

The increase of surfactaut synthesis and oxygen diffusion

The activation of adrenoreceptors of lung

The increase of viscocity of membrane structures of lung

The normalization of

excitability and contraction of

cardiomyocytes

The relatively

depresson

of specific for lung

pulse as thick, long




106

pereoxidation products, originated from heart cells membranes, and exhaustion of

Antioxidant defense systems, uncoupling of the oxygen delivery and consumption,

which at last resulted to damage of lung cells membranes, leading to disease

(Picture N 17).

Besides, it is raised the question: through what kind of material substances has been

occurred the process of transferring the information about the normal and

pathological state of functional activity of all solid and hollow organs,internally

existing in various places of Human body by the appearance of "normal", "cold", "hot"

character of pulse in arteria radialis, externally.

In the result of conducting the many series of experimental works by us established

that the lipid metabolites, released from membrane structure of corresponding solid,

hollow organs bringing in it's molecule, such vasoactive substances (molecules) as

adrenalin, serotonin, acethylcholin, endothelin, bradikinin, making the ciralation by

following path as: "target organ -» blood serum -» incorporation to membrane

structure of smooth muscle's cell (SMC) of vessel's wall leads to change of Ca2++

ton

permeability in sarcoplasmatic reticulum - change of interaction between action –

myosin - change of contraction of vessel's wall and the appearance of the normal,

cold, hot character of pulse i.e. increase of lipid pereoxidation products 'and ratio of

LPP/cholestrol in the lipid metabolites, released from MS of varions organs leads to

increase of fluid alpha state in MS of SMC and Ca 2 + +

ion permeability -

intensification of "actin - myosin interaction", contraction - the appearance of hot

character of pulse, meanwhile, decrease of lipid pereoxidation products /LPP/ and

the ratio of LPP/cholesterol in the lipid metabolites resulted to increase of solid betta

state in MS of SMC - increase the Ca2++

ton permeability - slowing of the "actin -

myosin interaction", decrease of contraction of vessel's wall - the appearance of cold

character of pulse (Picture № 15)




107

THE DISTURBANCE OF NORMAL MEMBRANE-REDOXY POTENTIAL

3 STATE – DEPENDENT “LEVER”MECHANISM OF APPEARANCE

OF HEALTHY PULSE IN AUTUMN SEASON

Picture №15

Pathological “counter

clockwise” rules

The disturbance of lever mechanism of membrane fluid alpha state and oxy potential regulation because

antioxidant deficiency

The appearance of

specific for heart pulse as

thick, long

The disturbance of

excitability and

contraction of

cardiomyocytes

The increase of

Detergent toxic lipid

pereoxidation products in

cardiomyocytes

membrane

The damage of MS of

lung organ by toxic,

detergent lipid

pereoxidation products,

originated in the

membrane-redoxy 3 state

system of

cardiomyocytes

Increase of the viscosity

of MS of lung cells

Decrease of

adrenoreceptor’s activity

of lung cell’s membrane-

redoxy 3 state system

Decrease of lung cell’s

functional activity and

limitation of the

appearance of specific

for lung pulse as

sharpy, rough.




108

THE PATHWAY OF TRANSFORMING THE PULSEDIAGNOSTTC INFORMATION

THROUGH LIPID METABOLITES OF MEMBRANE ORIGIN

The lipid metabolites of membrane origin of solid organs

Blood circulation

Ca2++

permeabilityi in the MS of sarcoplasmatic reticulum actin-myosin

interaction change of contractibiliry of smooth muscles of vessel's wall

The appearance of various forms (the normal, hot and cold character) of pulse

The membrane mechanism of Blood letting therapy and blood purifying

medicaments

The method of bloodletting practiced in three ways:

1. By puncturing the blood vessel

2. By sucking with the aid of a copper bowl, also known as cupping

3. By sucking with the aid of bulls horn Blood letting is allowed in cases of all kinds of

ailments of the fever, blood and Mkhris disease, red sores caused by the presence of

impure blood in the liver, coagulation of blood and lymph (fluid). The treatment of

Blood letting is prohibited in ailments caused by the psychotic action, deficiency of

body constituents, pregnancy, postnatal period, chronic diseases in a state of

passivity, deficiency in digestive fire. It is strictly avoided in case caused by the

disorder of rlung and Badgan.

The new conception on the membrane-redoxy potentials 3 state line system

related mechanism of Blood letting therapy

The reason why the scientic basis of Blood letting therapy of theory Traditional

Medicine should be explained in the level of membrane - redoxy potential 3 state line




109

dependent systems as 4 compartments and 10 functional systems comprising all 14

trillion cells of human body, it is connected with these facts that there are not really

existed a human species as ―Homo sapiens plus rlung, mkhris, badgan‖, ―Homo

sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan, yin‖ as if containing the 14

trillion living rlung, mkhris, badgan, yin, yanalong with 14 trillion living cells only

postulated by Traditional medicine doctors, all their diagnostic and treatment

methods based in this form of human specie, but categorically resisted, refused by

NCM medicine.

According to the our new conception, impure blood (according to theory of Traditional

Medicine) is one of parts of circulated blood, formed due to various pathology of all

the solid organs, consisting of form elements such as, erythrocytes, lymphocytes,

macrophages, subjected to the following pathological changes as:

1. During hot (fever) disease (according to theory of Traditional Medicine) paralled

with increase of alpha state of membrane structures, accompanied with a increase

of oxidation reaction speed, elevation of proton conductance, increase of proton

leak, increase of acceptor oxygen molecular concentrations, elevation of donator

utilization process, increase of metabolism rate, increase of pulse frequency,

increase of arterial pressure, increase of breathing frequency, increase of proton

gradient expenditure to heat formation, all these processes occured within all

organism's membrane - redoxy potentials 3 state line system lead to that in a

membrane structures of erythrocytes has been accumulated the more quantity of

toxic lipid pereoxidation products and their free movement limited, became slowly

and aggregated.

2. Owing to above mentioned pathological changes the erythrocytes and another

form elements have been acquired "immunosuppression" activity and also exerted

the hepatotoxic, cardiatoxic and nephrotoxic action.

3. In such way, during various disease of all the solid organs has been formed the

three cell population of erythrocytes in comparison with healthy state such as the

population of normal erythrocytes with a normal membrane - redoxy potentials 3 state

line system, the population of erythrocytes which membrane-redoxy potentials 3 state

line system subjected to reversible damage process, the population of erythrocytes

which membrane - redoxy potentials 3 state line system subjected to unreversible

damage process, acquiring the character of "impure blood" according to theory of

Traditioal medicine.




110

THE membrane - redoxy potentials 3 state line system related MECHANISM OF

BLOODING THERAPY

Picture № 16

Before bloodletting therapy

After bloodletting therapy

The population of erythrocytes, which

membrane-redoxy potential 3 state system

subjected to unreversible damage process

The population of erythrocytes, which

membrane structure subjected to reversible

damage process, so named “impure blood”

The population of erythrocytes




111

The population of erythrocytes, which membrane - redoxy potentials 3 state

line system subjected to unreversible damage process

The population of erythrocytes, which membrane - redoxy potentials 3 state

line system subjected to reversible damage process, taking a character of so

named "impure blood"

The population of normal erythrocytes with a normal membrane - redoxy

potentials 3 state line system

In the case of not using, applying the appropriate treatment, including the blood

letting therapy, blood purifying medicaments the last two population of erythrocytes

has been gradually increased and the population of normal erythrocytes had

subjected to lipid pereoxidation process, damaged, and converted to the population

of irreversible with a character of "impure blood" and reversible damaged

erythrocytes, acquiring the "immunosuppressive" activity.

It can be say that under the direct of blood letting therapy and blood purifying

medicaments has been removed from the human body the population of irreversible

damaged by lipid pereoxidation process population of erythrocytes, not losing the

population of erythrocytes, which may be converted from reversible damaged to

irreversible damaged population i. e in the case of appropriate use of blood letting

therapy, blood purifying medicaments during various disease of all the solid organs

has been occurred the transition from three cells population (normal, reversible,

irreversible) to two cells population (normal and irreversible damaged) by ensuring

the sanogenetic transform of irreversible damaged population to population of normal

erythrocytes with removing this population of erythrocytes, possessing

immunosuppressive, organotoxic activity (Picture N 18).

The experimental confirmation of the our conception

In the result of experimental research works conducted in rats, mice with

experimental model of "acute hepatite" induced by CCL4 (40% oil olution in dose

40%-0.5ml/kg) we are revealed that:

a. The blood letting therapy, the blood purifying medicament and lheir combined use

has been possessed the hepatoprotective action, which appeared in the form of

decreasing the serum concentration of alat, aspartatransferase, gamma-

glutamyltransferase enzymes

b. The hepatoprotective action of blood letting therapy, blood purifying medicaments

and their combined use has been accompanied with remarkable decrease of the

concentration of toxic lipid pereoxidation products in erythrocyte membranes

c. The sanogenetic process of decreasing the lipid pereoxidation products in

erythrocyte membrane under direct of blood letting therapy, blood purifying

medicaments and their combination resulted to intensification of immune response

reaction i. e the intraperitoneal administration (injection) of erythrocyte cells, obtained

from "donor" animals (rats, mice) with "acute hepatite" model, treated by blood letting




112

therapy and blood purifying medicaments to recipient animals leads to 1.3-1.4 fold

increase of antibody formation, quality of immunocytes and 1.2-1,4 fold decrease of

the concentration of lipid pereoxidation products in erythrocytes membrane structures

in comparison with recipient animals, received the erythrocyte population from

untreated control animals.

In such way the results of our investigation has been demonstrated that the

membrane mechanism of treatment efficacy of blood letting therapy and blood

purifying medicaments may be explained by removing, eliminating from the human

body and decreasing the irreversible and reversible damaged by lipid pereoxidaation

erythrocytes, lymphocytes possessing the organotoxic, immunosuppressive activity

under their direct effect.

Pharmacological aspects of the new conception

"rlung, Mkhris, Badgan – membrane - redoxy potentials 3 state line system.

According to the theory of Tibetan Mongolian -Traditional Medicine "... liver, as

mkhris /hot/ dominated organ is served the role of residence of general mkhris, and

also is existed in the place of healthy and pathologically changed mkhris. In this

connection, because of place, liver disease always has been provoked in the

background of hot disease, conditioned by excessive hot mkhris and blood . . . " .

Also, most attention should be paid to such interesting theoretical expressions of

TMTM as: "... the reason of mkhris dominated hot disease of liver is the normally

healthy existed Mkhris . . . ".

Undoubtely, raised the question in regarding to how explain thisabovementioned

theoretical expression of TMTM, relating to reason of liver disease in the basis of the

new conception "rlung. Mkhris, Badgan - membrane - redoxy potentials 3 state line

system".

In the result of conducting by us the more detailed scientific investigation in the

framework of the new conception "rlung. Mkhris, liadgan – membrane - redoxy

potentials 3 state line system." has been revealed that, in comparison with other solid

organs, in the membrane structure of hepatocytes prevailed the fluid alpha state i. e

during evolution development of li ving organism had been formed such lawfull

process that all the membrane structure, which existed in hepatocytes had created

by low viscous, cis - configuration, ensuring the high activity of thermogenesis,

membrane binding receptors, "receptor - hormon", "enzyme -substrate" interaction,

besides, such fluid alpha state, cis - configuration of MS, performing, ensuring the

high functional activity of liver cells easily subjected to lipd pereoxidation process,

resulting to cytolysis i.e it may be say that the prevailence of fluid alpha state of MS

in hepatocytes had the two basic sanogenetic and pathogenetic consequences: at

first created the precondition for activation of all membrane binding molecules and

receptors, thermogenesis, enzymes, at second conditioned the easy susceptibility of




113

hepatocytes membrane structure to harmfull action of pathogenetic factors, resulting

to the hot mkhris disease of liver. Therefore, according to existence of close

coincidence, which appeared as "alpha state of MS - general characteristics of

Mkhris" it was became clear that the scientific essence of the theory of TMTM about

that ". . . the healthy existed Mkhris is the main reason of hot, mkhris disease of liver

..." should be explained by these facts, that which may be express in (he following

ways as " . . . the normally existed fluid alpha state of MS with high oxidation activity

of hepatocytes (according to the theory of MTM the normal Mkhris of liver), except

playng the role for activation of hepatocytes, increase of deficiency of antioxidant

defense system easily subjected to pathological factors, becoming the reason of

disease.

Such our suggestion and conclusion has been confirmed by the results of our

following research works:

1. In liver cells the intensity of lipid pereoxidation process, which provocated due to

fluid alpha state, cis-configuration of MS with high oxidation activity was in 1.2-7.5

times high than other solid organs.

2. The intensity of induction of lipid pereoxidation process under the prooxidant

action of CCL4 was 1.64-4.21 times high than other solid organs by concentration of

deprotonized MDA, DK and shiff base (P<0.05) products .

3. The intensity of provocation of lipid pereoxidation process in MS of liver cells under

toxic action of CCL4 was in 1.6-1.8 times high in the case of artificial induction of

predominance of fluid alpha state by using the unsaturated phospholipids than

induction of solid betta state of MS by using the saturated phospholipids and

cholesterol.

In such way, the results of above mentioned experimental works and the new

conception "rlung. Mkhris, Badgan - membrane - redoxy potentials 3 state line

system" and the tradition of using of Medicaments, possessing bitter taste, cool,

stupid, cold power, quality for treatment of liver hot disease in TMTM gives the

ground to use the medicinal plants, which possessed antioxidant,

membranestabilitizing, fluid alpha state-limiting capacity and also trans -

configuration containing compounds, which increased the solid betta state of MS of

hepatocytes for treatment of acute form of liver disease.

In this regard, by us had been selecting the some plants: as Chiazospermum

erectum, Silibum marrianum, Gentianae acuta, Salsola collina for testing their

hepatoprotective action.

In the result of conducting the experimental research works in the model of acu te

hepatite, induced in mice, weighting 18-20 gr by undercutaneous injection of 40%

CCL4 we are established that:

a. The sum of alkaloids from Chiazospermum erectum, sum of flavonoids from

Lomatogonum rotatum, Silibum marrinum, Gentianae acuta and their combination

had been exerted the hepatoprotective action in the form of decreasing the




114

concentration of toxic lipid pereoxidation products in MS of hepatocytes, serum Alat,

aspartattransferase activity and inhibiting of excessive unregulated activation of

immunoresponce reaction and increasing the intoxication, proteinsynthizing activity of

hepatocytes.

b. The water and Alcohol (ethanol) extraction of Salsola collina had been possessed

the hepatoprotective action by antioxidant, membrane stabilizing, immunocorrecting

mechanism, which has been carried out in the background of increasing the solid -

betta state in MS of hepatocytes and decreasing the excessive pathological

predominance of fluid alpha state of MS.

In such way, in the result of establishing their hepatoprotective action we are obtaing

the new hepatoprotective preparations "Barbadin", "Silodin", "Salsomon" from

Chiazosperum erectum, Gentianae acuta, Lomatogonum rotatum, Silibum marrianum

and Salsola collina and introduced in the Medical practice (Picture N 20).

The new immunostimulator preparation and the new conception "rlung, Mkhris,

Badgan- membrane-redoxy potentials 3 state line system.

The normal function and specifics of pathological processes of spleen, which 80 -

90% of cell populations consists of T-lymphocyte, T-helper, T-suppressor, T-effector

(killer), B-lymphocytes and Macrophages had been described in the theory of TMTM

as: "spleen is one of solid organs, playing the most important role in stomach

digestion, because, spleen is existed in the way of circulation and recirculation of

healthy badgan and pathologically changed badgan. The disease of spleen is caused

by cold badgan. . . "

In the result of conducting the research works, directed to explanation of scientific

essence of above mentioned theoretical formulations, regarding to spleen function

and cause of spleen disease we are revealed the following interesting lawfull

phenomenons:

a. In the membrane structure of spleenocytes the intensity of lipid pereoxidation

process was in 2.3-4.0 times slow than other solid organs i. e it has been prevailed

the solid betta state of MS within membrane - redoxy potentials 3 state line

system.

b. In the case of inducing the two variants of predominance of basic states of MS in

the spleenocytes, such as alpha fluid state by administration of unsaturated

phospholipids (0.5 ml/kg), betta-solid slate by administration of saturated

phospholipids and cholesterol (250 mg/kg), the predominance of alpha fluid state in

MS of spleenocytes in autumn season (alpha + alpha states of MS) has been

accompanied with 1.36 -1.4 fold increase of antibody titer, 1.6-1.7 fold increase of

immunocytes in comparison with betta solid state of MS, in spring season (season

related increase of betta states) i.e the results of our investigation shows that the

increase of solid betta state in MS of spleenocytes under direct effect of saturated




115

fatty acids, cholesterol and sprimg season, low temperature (cold) in the form of

(betta + betta + betta) leads to sharply decrease of immune response reaction, which

may be expressed in the theory of TMTM ". . . the spleen is subjected to disease and

deficience because of cold badgan . .. ".

In the result of conducting the experimental research works, which has been directed

to establish the immunostimulator activity of Salsola laricifolia, Oxytropis

pseudoglandulosae used in TMTM for treatment of various infectious disease and

immunodeficience pathology we are revealed that:

a. The sum of polysaccharids from Oxytropis pseudoglandulosae and the sum

coumarins from Salsola laricifolia had been exerted the immunostimulator action in

the two models of predominance of alpha fluid state or betta solid state of MS: as

"alpha + alpha + alpha" and "betta + betta + betta" by increasing the antibody titer

in 1.2-1.45 times, the quantity of immunocytes in 1.25-1.55 times and decreasing the

concentration of lipid pereoxidation products in MS of spleenocytes in 1.3-1.52 times

(p<0.05).

b. The intensity of immunostimulator activity of Salsola laricifolia and Oxytropis

pseudoglandulosae increased in 1.2-1.3 times by the antibody titer, and the

quantity of spleenocytes in the case of predominance of fluid state of MS

("alpha + alpha + alpha") in comparison with the predominance of betta solid state

of MS ("betta + betta + betta") i.e the results of our investigation has been

demonstrated that combination use of Salsola laricifolia and Oxytropis

pseudoglandulae with unsaturated fatty acids -main modificator of fluid alpha state of

MS leads to magnification of their immunostimulator activity, which gives the

possibility to explain the scientific essence of theoretical expressions of TMTM as ". .

. warm, oily foods contributed to dispell the cold badgan from spleen and leads to

amplification of immunostimulator activity of Medicaments . . . "by "alpha +

alpha + alpha" mechanism, occurred in MS of immunocytes and spleenocytes. In

the result of conducting the above mentioned experimental workswe are

obtaining two new immunostimulator preparations "Salorid", "Ortuuzin" and

introduced to medical treatment practice. (Picture N 20).

The new nephroprotector preparation and the new conception "rlung, Mkhris,

Badgan - membrane-redoxy potentials 3 state line system.

In the theory of TMTM had been emphasized that "kidney, as badgan dominated

organ served the residence of healthy badgan and the way of circulation of

pathologically changed badgan. . . In this connection the kidney disease is

conditioned by cold badgan . . . ". In the result of our comparative experimental

research works has been stated by us that, the intensity of induction of lipid

pereoxidation process in the MS of kidney cells was in 1.2-1.3 times slow than MS of

liver cells in autumn season, but these findings were in 1.2-1.36 times high in spring




116

season. In such way the results of our investigation demonstrated that kidney cells

have the most specific character by their ability to conduct the adaptive reaction by

increasing the unsaturated fatty acids fluid alpha state of MS under low temperature

(cold) and by increasing the saturated fatty acids - solid betta state of MS under

influence of high temperature (hot).

It was very interesting that during our experimental works by us has been established

that in case of inducing the predominance of solid betta state of MS by low

temperature and saturated fatty acids (cholesterol) the volume of diuresis of

laboratory animals increased in 1.3 times in comparison to animals with

predominance of alpha - fluid state of MS. Basing in these results of our investigation

we came to conclusion that the scientific essence of theoretical expressions of TMTM

about ". . . increase of cold badgan in kidney and the diuresis under direct effect of

low temperature and cold foods ..." would be explain by such lawfull process, which

has been carried out in following consequence: as "cold food, low temperature - the

predominance of solid betta state of MS in kidney cells inactivation of kidney Na+, K

+-

ATP - ase enzyme the decrease of the K+, Na+ reabsorption - the increase of

diuresis".

In this way, the some date of foreign researchers (S.Rjabov 1998) who established

that during acute nephrites has been accumulated the toxic lipid pereoxidation

products and cholesterol on MS of kidney cells, increased the viscocity of MS, and

the results of our above mentioned research experimental works gives the ground to

say that the medicaments of plants origin, possesing the immunomodulator,

antioxidant and membranestabilizing activity may be exhibit the nephroprotective

action.

In this connection we are choosen the Iris tenufolia as object of our further

investigation, which had been used in TMTM for treatment of various forms of kidney

disease, it was stated by us that the ethanol extraction obtained from Iris tenufolia

exerted the nephroprotective action by decreasing the accumulation of toxic lipid

pereoxidation products in MS of kidney cells and serum concentration of kreatinin

and urea, inhibiting the excessive increase of more viscous solid betta state of MS in

kidney cells and attennuating the cytotoxic immune reaction, decreasing the acute

damage of kidney cells.

Basing in the results of this experimental investigation we are obtained the new

nephroprotective preparation "Nephromon" and introduced to medical treatment

practice (Picture №20).

The new cardioprotective preparation and the new conception "rlung, Mkhris,

Badgan- membrane-redoxy potentials 3 state line system

According to the theory of Traditional Medicine. ". . .The heart as rlung dominated

solid organ is existed in the residence of general "rlung" way, acted under the




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regulation of "general rlung". In this connection, the heart is easily subjected to

disease, which are accompanied with unsufficiency of high energy phosphate - ATP,

high energy electrons - NADPH, provocated in the background of gamma state of

membrane structure with low level of redoxy potentials ability because of excessive

accumulation of abstracted by thermin rlung really existing substance . . .The

accumulation of abstracted by thermin rlung really existing substance in heart

has been carried out under the direct influence of using of fatless foods, /goat/

possessing light, cool power and quality. . . ", these according to the new

conception "rlung, Mkhris, Badgan – membrane - redoxy potentials 3 state line

system lead to unsufficiency of high energy phosphate - ATP, high energy electrons

- NADPH, resulting to the elevating of gamma state of membrane structure with low

level of redoxy potentials.

In the result of interpretation the scientific essence of theoretical formulations of

TMTM regarding to function and cause of heart disease we came to conclusion that

the abovementioned factors, foods, which served the role of cause of heart disease

had been characterized by deficiency of antioxidant defense system and the capacity

to induce the lipid pereoxidation process in membrane structures of cardiomyocytes,

i.e. long term use of foods, which according to the theory of TMTM contributed to

induction of heart disease leads to the accumulation of "detergent" lipid pereoxidation

products in the MS of cardiomyocytes and the damage of ion /Na+, K

+, CL ion

conductivity, also the disturbance of "normal action potential", the defect of normal

process of contraction and excitability of cardiomyocytes, all these processes may be

expressed in the theory of TMTM as "pathological increase of rlung, located in the

heart". In the result of conducting the experimental research works, we are

established that the normal cardiac function and ion conductivity of cardiac muscles,

also the resistance of cardiomyocytes to arrhytmic action of CaCI2 /in 1.3-1.4 times/

has been disturbed and alterated in the case of modifying the normal state of MS by

insaturated and saturated fatty acids in the form of causing the pathological

predominance of fluid alpha and solid betta states of MS.i.e. the normal function of

cardiomyocytes has been influenced by balance between three basic state of MS of

cardiomyocytes.

In such way, on the basis of our experimental works, during which we are established

that the disturbance occured in the relationship as "the heart function - normal

intermediate gamma - state of MS - normal speed of excitability and contraction of

cardiomyocytes" had resulted to cardiac disease, we are putting before us the goals

to study the cardioprotective action of sum flavonoids from Astragalus variabillis and

Astragalus galactites, containing the polyphenol complex, which possessed the

antioxidant, membrane stabilizing activity. It was shown that sum flavonoids from two

species of Astragalus has been possessed the cardioprotective, antiishemic action

by decreasing the myocardial infarction size /in 1.5-1.8 times/, the size of

nonvascularization cardiac muscles and the size of pathological dilatation of the




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ventricle cavity, also diminishing the ST segment elevation and the depth of

necrosogenic Q waves in EKG during the acute coronaroocclusion myocardial

infarction models, induced in Rats.

The results of our experimental investigation gives to us the possibility to obtain the

new cardioprotective preparation "Astradin", "Asvargal" and introduce these two

preparations in Medical practice.

The new conception "rlung, Mkhris, Badgan - membrane - redoxy

potentials 3 state line system" and the pharmacological study of some

anticancer preparations.

In can be say that according to the theory of rlung, Mkrhis, Badgan and five elements

of TMTM the cancer belongs cold - induced, abstracted by thermin badgan disease.

If explain these theoretical expressions of Traditional Medicine in the framework of

the new conception "rlung, Mkhris, Badgan - membrane - redoxy potentials 3 state

line " the cancer process is caused by unregulated increasing of the solid betta state

and the viscosity of MS with high reduction potential, when are elevated high energy

phosphate- ATP, high energy electrons - NADPH, thereby creating a precondition of

excessive activation of cell division process in cancer cells (CC) by mecchanism as

active G1 – Cdk - active Rb protein-active E2F protein – S - phase gene

transcription-active G1/S - Cdk-active S – Cdk - DNA synthesis.

The above mentioned comparative theoretical analysis gives the possibility to say

that one of ways of inhibition of cell division during the cancer should be directed to

decrease of excessive solid betta state of MS of CC by using the medicaments,

containing the unsaturated fatty acids and conjugated fatty acids, which contributed

to increase of the fluid alpha state of MS with induction of phase transition in the

direction of "from betta state to alpha state", "from elevated reduction potential

to elevated oxidation potential "... In this connection we are studied the anticancer

activity of "Ellipin" obtained from fermented bovine liver and contained the more

quantity of unsaturated fatty acids and conjugated fatty acids with high oxidation

ability .

There have been many epidemiological and animal studies concerning dietary fatty

acids related to tumors. According to literature date some fatty acids selectively

suppress tumor cells, without affecting normal cells. The purpose of this investigation

was to analyze the chemical composition of lipids named Ellipin (YS2H) extracted

from bovine liver and to examine the antitumor effects and possible mechanisms of

Ellipin (Picture N 20).

Ellipin was extracted from X-ray irradiated and fermented bovine livers by Folch's

modified method. The chemical composition was analyzed, using chemical methods,

thin-Layer chromatography, gas chromatography and high performance lipid

chromatography. The antitumor effect and its mechanisms were studied on Hela,




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Raji, J6.2, K562 tumor cell lines in vitro, and lymphogenous Leukemia (L615) and

astrocytoma (G442) in mice in vivo. Ellipin was mainly composed of free fatty acids

(FFAs), phospholipid, cholesterol and triacylglycerol. The major FFAs in Ellipin were

C14:0, C16:0, C18:l, C18:2, C20:4 and conjugated linoleic acid (CLA).

Ellipin significantly suppressed the growth of K562, J6.2, Raji and Hela and inhibited 3H-TdR incorporation by J6.2, and K562. The growth of G442 was significantly

suppressed by oral administration of 3-0.6 g Ellipin (Kg, daily, for 14 days). The NK

activities of spleen lymphocytes from Ellipin-treated mice were greatly higher than

that of untreated controls. The proliferation response of T lymphocytes from spleen of

mice treated with to mitogen (con A) also was obviously elevated, compared with that

of untreated one. The immunization of mice with Ellipin-treated L6]5 tumor cell vaccine

induced very strong effects may be the complex FFAs including CLA and other

unknown substances in Ellipin.

Ellipin has significant antitumor efficacy on G422 in mice by oral administration. The

antitumor efficacies of Ellipin might be correlated to killing tumor cells directly and

strengthening the host immunities mediated by T lymphocytes indirectly. Tumor cells

of Ehrlich ascites carcinoma (EAC) and hepatoma (H22), uterine carcinoma

(Uu) and sarcoma (S180) were inoculated in each. Into Kum Ming mice of weighting

18±2g respectively. The cells inoculated were 3xl06 for EAC and 2xl0

5 for H22-

intraperitoneally, 5xl06 for U14 and 2xl06 for S180 series subcutaneously. Twenty four

hours later, the mice with each cell line series were divided into 6 of 3 experimental

and 3 control groups, and heplipin of 300 to 500 mg/kg body weight was injected

intraperitonelly, daily, for 7 to 14 days, Normal saline, Vehicle, another antitumor

agents were used as negative and positive controls. Life span was observed by 60

days for the series of mice with EAC and H22 at 24 hours after last injection of Ellipin,

mice with U14 and S80, series werekilled and observed inhibitory rates by weighting

tumor.

Inhibitory effects of Ellipin to tumor growth were larger enough than those of another

anticancer agents used as positive controls. Life span inducated by survival rate was

increased by 90% in EAC and 70% in H22 mice. LD50 was 8.0g/kg for the oral and

1.64g/kg for intraperitoneal administration.

The anticancer efficacy of Ellipin was excellent with wide spectrum to various cell

line, Ellipin could elongated life span of the mice with cancer, and there was no

serious side effects indicating acute toxicities both in oral and intaperitoneal

administration, indicating a good anticancer agent for cancer.

In the present studies, significant cytotoxicities of Ellipin in vitro on K 562 and J612

Leukemic cell lines and very effective antitumor activities on implanted U14 and EAC

were demonstrated indicating that the active constituents of if s antitumor effect may

be fatty acids, in particular conjugated one, which induced in the MS of cancer cells

the transition in the forms as from betta state to alpha state, resulting to decrease of

cell division and DNA synthesis.




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Obtained results had confirmed that suggested by us new conception, according to

which tumor related pathology belongs to cold Badgan Disease and should be

successfully treated by preparation, containing conjugated fatty acids - main

component of a - state of MS with high oxidation activity, which expressed in theory

of MTM as prescription, possessing hot, oil property and power, under this action

would occur the process as within membrane - redoxy potentials 3 state line of

cancer cells happened the process of transformation as "from betta state to alpha

state", "from elevated reduction potential to elevated oxidation potential "with

lessening of high energy phosphate - ATP, high energy electrons-NADPH, thereby

creating a precondition of supression of cell division process in cancer cells (CC)

by mecchanism as low level of ATP, NADPH - low level of phosphorylation of Rb

protein - low level of active G1-Cdk- low level of active Rb protein - low level of

active E2F protein - low level of S - phase gene transcription - low level of active

G1/S-Cdk- low level of active S - Cdk - low level of DNA synthesis.

EDUCATION ASPECTS OF NCM MEDICINE

The reason why we are proposing the teaching program as ―NCM medical education

in the 21 century, including Traditional and Modern medicines, connected by new s-

NCM knowledge‖ it is connected with these facts that s-NCM new knowledge,

connected with a membrane - redoxy potential 3 state line dependent systems as 4

compartments and 10 functional systems comprising all 14 trillion cells of human

body was became a key points of this program.

Now we should not lost the historical possibility to use simuletuneously 3 various

knowledge created by Traditional Medicine also Modern medicine and NCM

medicines, connected by new s-NCM knowledge‖.

Their demands and requists are follows:

1. In connection with this that prevailed the imagination that human body consists of

really existing living 14 trillion rLung, mkhris, badgan instead of 14 living cells, the

conducting of training process of Traditional Medical doctors based only in the X, G

knowledge of Traditional Medicine do not give positive result to implementation of

the new medical education program “NCM medical education in the 21 century,

including Traditional and Modern medicines, connected by new s-NCM

knowledge”.

2. But when appeared the new conception - the coincidence of really existing 14

trillion living cell membrane - redoxy potentials 3 state regulation is the substance of

forming the theory of rLung, mkhris, badgan, training process of Traditional

Medical doctors based in the X, G knowledge, in addition to it S knowledge of

Modern medicine , integrated through s-NCM knowledge, would give positive result




121

to implementation of the new medical education program “NCM medical education

in the 21 century, including Traditional and Modern medicines, connected by

new s-NCM knowledge”.

The world tendency of development traditional education medical system

In the framework of new medical education program ―NCM medical education in the

21 century, including Traditional and Modern medicines, connected by new s-NCM

knowledge‖ we put the goal to evaluate our gained achievement since proposing a

new conception as ―rlung, mkhris, badgan abstract coding and three states of

membrane structures and redoxy potentials‖, ―The one cell – two medicine‖ new

conception in 1990 in comparision with analogical investigations, carried out around

world by other researchers of forein countries.

a. As other researchers, who are conducting a analogical investigations, by us were

choosen – a study of professor Prasher B, Institute of genomics and integrated

Biology in the field of India-Aurveda medicine, study of professors Hyun-Ju Kim, Bu -

Yeo Kim, Korea, Institute of Oriental Medicine in the field of Korea - Sa Sang

medicine, study of professor Yanrui Wu - Beijing University of Chinese Medicine in

the field of Chinese traditional medicine - Yang - Ying theory.

b.To evaluate the gained achievement in the field of elucidation of theorertical

aspects of Oriental medicine, made by researchers, who are conducting a analogical

investigations with attempts to find common language between basic theoretical

aspects of Oriental and Modern medicine and build a scientific bridge between basic

theoretical aspects of Oriental and Modern medicine we are used a following a

basic parameters as:

1. A achievements in the direction of finding of corresponding genome expression of

individuals, belonging to three and four types of constitutions

2. A achievements in the direction of finding of corresponding biochemical

correlates of individuals, belonging to three and four types of constitutions, according

to Modern medicine and Biology analogous findings

3. A achievements in the direction of proposing the new conception, comprising all

aspects of basic theory of Oriental Traditional and Modern medicines

4. A achievements in the direction of finding of corresponding morphofunctional

correlates of individuals, belonging to three and four types of constitutions, which are

existed in accordance with Modern medicine and Biology analogous findings

5. A achievements in the direction of developing the new methodological approach,

which could be used to find common language between basic theoretical aspects of

Oriental and Modern medicine and build a scientific bridge between basic theoretical

aspects of both medicines

6. A achievements in the direction of establishing the common language and

bridges between basic theoretical aspects of Traditional and Modern medicines

7. A achievements in the direction of Introduction of common language and builded

bridge in to research works, diagnostic and treatment practice, training practice




122

8. A achievements in the direction of creation of independent – third new medical

system in the result of finding a common language between basic theoretical aspects

of both medicines

9. A achievements in proposing absolutely new cognitive decision in the science,

which serves the role of common language and bridge of likage detween basic

theoretical aspects of Oriental and Modern Medicines.

We are shown here the Traditional medical doctor, graduates competency, relating

to their ―knowledge – practice - attitude, who able to conduct the diagnosis, reatment

by Traditional Medical principle, simultuneously the diagnosis‖, treatment by Modern

Medical principle, and also the diagnosis, treatment by new NCM medicine principle

.

As examples we take the thematics as resting potential.

The graduates - Traditional medical doctors, trained by program ―NCM medical

education in the 21 century, including Traditional and Modern medicines, connected

by new s-NCM knowledge‖ able to analyze these thematic as …The resting cell is

not resting at all but very busy controlling the state of its interior, and it required a

continuous supply of energy to do so.

Also, the graduates - Traditional medical doctors, trained by program ―NCM medical


by new s-NCM knowledge‖ know that, according to theory of Traditional medicine,

the disturbance of a continuous supply of energy of the resting cells, described as

rLung disease (Lobsang Rapgay) in Traditional medicine by thermions as

Restlessness, Deliurum, Anger, Amnesia, Neuronic disturbances.



by new s-NCM knowledge‖ know that the disturbance of a continuous supply of

energy of the resting cells, according to NCM medicine - s-NCM knowledge would be

caused because of predominance of gamma state of membrane structures and

slowing of redoxy potentials and high level of proton leak, slip potentials and

shortage of high energy phosphate - ATP, of high energy electrons - NADPH, also

heat energy because of slipping in redox and ATPase H + pumps (Pietrobon D,

Zoratti M, Azzone GF) with dependence of the membrane 'leak' conductance for H+.

The full cognitive interpretation of medical knowledge of all period of humanity give

the possibility to solve all problems of medicine, relating to the normal existence,

disturbance of normal existence of human body, their diagnosis and treatmen by

using fully membered metabolism equition, which include a G knowledge of

Traditional medicine + X – knowledge of Traditional medicine + S - knowledge of

Modern medicine + s-NCM knowledge of NCM medicine, whicn formed during of all

period of developing of various medical systems of humanity.

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Pietrobon%20D%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Zoratti%20M%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Azzone%20GF%22%5BAuthor%5D




123

But since 1990 year in the medical thinking abruptly changed, acquiring completely

new character because of appearing the s-NCM new knowledge and the ―g + X

knowledge + S knowledge + s-NCM knowledges, decided all questions by new

approach as “Traditional medical X, G - knowledge + Modern medical S-

knowledge + s-NCM new knowledge = secrets of normal existence of human

body - key cause of pathological change-their diagnostics-their treatment‖.

1. According to Traditional medical system the balance of of normal status existing

of human body are determined by balance of 20 external patterns and 5 elements,

balance between rlung: mkhris: badgan.

2. According to Traditional medical system the key cause of pathological change,

occurred in human body are determined by disbalance of X + G knowledge based

parameters, including 20 external patterns and 5 elements, disbalance between

rlung: mkhris: badgan.

3. According to Traditional medical system diagnostics of pathological change,

occurred in human body are based in establishing the disbalance of X + G

knowledge based parameters, including 20 external patterns and 5 elements,

disbalance between rlung: mkhris: badgan.

4. According to Traditional medical system treatment of pathological change,

occurred in human body are based in correcting of the disbalance of X + G

knowledge based parameters, including 20 external patterns and 5 elements, also

in correcting of the disbalance between rlung: mkhris: badgan.

B. Modern medical system laid a foundation of living cell level S knowledge, used

them to solution of a main urgent problems of medicine, consisting following 4

parameters as ―secrets of normal existence of human body - key cause of

pathological change - their diagnostics - their treatment ―but is lacking of X + G

knowledge, in this connection Modern medical education system are based S

knowledge without using X + G, s-NCM knowledges to teach a main urgent

problems of medicine as ―status of normal existince of human body - key cause of

pathological change - their diagnostics - their treatment ―to students.

1. According to Modern medical system the balance of of normal status existing of

human body are determined by balance of living cell level S – knowledge related

parameters.

2. According to Modern medical system the key cause of pathological change,

occurred in human body are determined by disbalance of living cell level S –

knowledge related parameters.

3. According to Modern medical system diagnostics of pathological change, occurred

in human body are based in establishing the disbalance of living cell level S –


4. According to Modern medical system treatment of pathological change, occurred

in human body are based in correcting of the disbalance of living cell level S –





124

C. What about advantage of NCM new medicine, which are used a Traditional

medical X + G knowledge, addition to it, used a Modern medical system S

knowledge, besideit is introducing the s-NCM new knowledge, thereby laid

foundation new NCM medicine able decide a main urgent problems of medicine, as

―status of normal existence - key cause of pathological change - their diagnostics -

their treatment‖ by using full integrated “Traditional medical X, G - knowledge +

Modern medical S-knowledge + s-NCM new knowledge”, in this connection

NCM new medical education system are based “Traditional medical X, G -

knowledge + Modern medical S-knowledge + s-NCM new knowledge” to teach

a main urgent problems of medicine as ―the basis of normal existing of human body

- key cause of pathological change - their diagnostics - their treatment‖ to students.

1. According to NCM new medical system the balance of of normal status existing of

human body are determined by balance of membrane - redoxy 3 state line systems,

representing the first compartment, serum-fluid second compartment, and fourth

compartment, consisting of 5 membrane structures-5 function systems, ensuring

normal genetic - cell division, information-response, biosynthetical, bioenergetical,

biotransformation functions, also, third compartment, representing a visceral and

external fatty depositions, coded by abstract mkhriss, rlung, Badgan code in the

Tibetian Mongolian Traditional medicin and in the living cell level S parameters by

using full integrated ―Traditional medical X, G - knowledge + Modern medical S-

knowledge + s-NCM new knowledge‖ .

2. According to NCM new medical system the balance of of normal existing of

human body are determined by disbalance of membrane - redoxy 3 state line

systems, representing the first compartment, serum-fluid second compartment, and

fourth compartment, consisting of 5 membrane structures - 5 function systems,


bioenergetical, biotransformation functions, also, third compartment, representing a

visceral and external fatty depositions, coded by abstract mkhris, rlung, Badgan

code in the Tibetian Mongolian Traditional medicin and in the living cell level S

parameters by using full integrated ―Traditional medical X, G - knowledge + Modern

medical S-knowledge + s-NCM new knowledge‖.

3. According to NCM new medical system diagnostics of pathological change,

occurred in human body are based in establishing the disbalance of membrane -

redoxy 3 state line systems, representing the first compartment, serum-fluid second

compartment, and fourth compartment, consisting of 5 membrane structures-5

function systems, ensuring normal genetic - cell division, information - response,

biosynthetical, bioenergetical, biotransformation functions, also, third compartment,

representing a visceral and external fatty depositions, coded by abstract mkhris,

rlung, Badgan code in the Tibetian Mongolian Traditional medicin and in the living

cell level S parameters by using full integrated ―X + G + S + s-NCM‖ knowledges.




125

4. According to NCM new medical system treatment of pathological change, occurred

in human body are based in correcting the disbalance of membrane - redoxy 3 state

line systems, representing the first compartment, serum - fluid second compartment,

and fourth compartment, consisting of 5 membrane structures-5 function systems,

ensuring normal genetic-cell division, information-response, biosynthetical,

bioenergetical, biotransformation functions, also, hird compartment, representing a

visceral and external fatty depositions, coded by abstract mkhris, rlung, Badgan

code in the Tibetian Mongolian Traditional medicin and in the living cell level S

parameters by using full integrated “Traditional medical X, G - knowledge + Modern

medical S-knowledge + s-NCM new knowledge― knowledges. In this way the

cognitive uncoincidence existing between X + G medical knowledge of Traditional

medicine and S knowledge of Modern medicine, relating to urgent quiestion of

medicine as ―secret of normal existing of human body - key cause of pathological

change - their diagnostics - their treatment‖ decided through s-NCM new knowledge

developed, proposed by us, thereby these barriers are demolished.

The graduates - Traditional medical doctors model, trained by program “NCM

medical education in the 21 century, including Traditional and Modern

medicines, connected by new s-NCM knowledge would be stand out by

following skills:

1. Traditional Medical doctors should possess the foreig language ability, ratified by

state examination to translate all Tibetan materialls, written in a old sutaras and

Language ability, ratified by state examination to translate all proffessional materialls,

written in English language, also ability to to write History of disease, diagnostic

therminology in Russian language.

2. Traditional Medical doctors should possess the theoretical knowledge, practical

skills to conduct Traditional medical diagnosis, treatment of inner disease,

acupuncture, to use traditional receipts, according State standartization MNS 2008.

3. Traditional Medical doctors should possess the basic theoretical knowledge,

practical skills to conduct every day Diagnosis and treatment with using of integrated

medical knowledges in the form as Traditional medical X, G - knowledge + Modern

medical S-knowledge + s-NCM new knowledge in relation to a main urgent problems

of medicine, as the basis of normal existince of human body - key cause of

pathological change - their diagnostics - their treatment‖, with accounting the

membrane - redoxy 3 state line systems, representing the first compartment, serum -

fluid second compartment, and fourth compartment, consisting of 5 membrane

structures - 5 function systems, ensuring normal genetic - cell division, information-

response, biosynthetical, bioenergetical, biotransformation functions, also, third

compartment, representing a visceral and external fatty depositions, coded by

abstract mkhriss, rlung, Badgan code in the Tibetian Mongolian Traditional medicine.




126

4. Traditional Medical doctors should possess the basic theoretical knowledge,

practical skills to understand the scientific essnce of Traditional pulse, urine, five

flower diagnostic principles in the frame of the membrane - redoxy 3 state line

systems, representing the first compartment, serum - fluid second compartment, and

fourth compartment, consisting of 5 membrane structures - 5 function systems,


bioenergetical, biotransformation functions, also, third compartment, representing a

visceral and external fatty depositions, in close with abstract mkhris, rlung, Badgan

coding of Tibetian Mongolian Traditional medicine.

5. In case of planning of diagnostic and treatment strategies in every patients

should possess the basic theoretical knowledge, practical skills, thinking ability,

attitude to distinguish that which pathological process initiated in which parts of

membrane - redoxy 3 state line systems, representinf first compartment, in which

parts serum - fluid second compartment, in which parts of fourth compartment as 5

membrane structures - 5 function systems, ensuring normal genetic-cell division,

information-response, biosynthetical, bioenergetical, biotransformation functions, in

which part of third compartment, representing a visceral and external fatty

depositions, coded by abstract mkhriss, rlung, Badgan code in the Tibetian

Mongolian Traditional medicine, how emerged all kinds of treatment effects in them

by using Traditional Medical diagnostics and treatment system, also, Modern

Medical diagnostics and treatment system, in addition to it, diagnostics and treatment

system NCM medicine in complience with them choose a appropriate treatment

decisions.

6. In case of choosing of rational use of Traditional medicaments, acupuncture,

traditional massage therapy in every patients should possess the basic theoretical

knowledge, practical skills, thinking ability, attitude to understand their treatment and

correction effects would occure in which pathological process initiated in which parts

of membrane - redoxy 3 state line systems, representinf first compartment, in which

parts serum - fluid second compartment, in which parts of fourth compartment as 5

membrane structures - 5 function systems, ensuring normal genetic - cell division,

information - response, biosynthetical, bioenergetical, biotransformation functions, in

which part of third compartment, representing a visceral and external fatty

depositions, coded by abstract mkhris, rlung, Badgan code in the Tibetian Mongolian


7. In case of conducting of Traditional diagnostic procedures in every patients by

using of computerized DocAm-1 programm should possess the basic theoretical

knowledge, practical skills, thinking ability, attitude to establish the correlation

between the status of membrane - redoxy 3 state line systems, representinf first

compartment and their abstract mkhris, rlung, Badgan coding and the link between

the status of serum - fluid second compartment and their abstract mkhris, rlung,

Badgan coding, also the correlation between the status of fourth compartment as 5




127

membrane structures-5 function systems, ensuring normal genetic-cell division,

information-response, biosynthetical, bioenergetical, biotransformation functions and

their abstract mkhris, rlung, Badgan coding, in addition to it the link between the

status of third compartment and their abstract mkhris, rlung, Badgan coding and

the pathological influences, occuring between a first, second, third and fourth

compartments.

8. Traditional Medical doctors should possess the systemized - ordered basic

theoretical knowledge, practical skills to unite the content of all 80 lessons in the

frame of equation as ―Traditional medical X, G - knowledge + Modern medical S-

knowledge + s-NCM new knowledge = the solution of a main urgent problems of

medicine, as‖ secrets of normal existence of human body -key cause of pathological

change - their diagnostics - their treatment‖, unserstand the essence of Traditional

medicine lessons by using the X, G knowledges, unserstand the essence of Modern

medicine lessons as biochemistry, immunology, physiology by using the S

knowledges, also use them in close context with s-NCM new knowledge by principle

as ―All 80 lessons and one action moment of Diagnosis, treatment of Traditional

medical doctors‖

9. Traditional Medical doctors should possess the systemized-ordered basic

theoretical knowledge, practical skills at first to establish the pathological change of

the membrane - redoxy 3 state line systems, representing the first compartment,

serum-fluid second compartment, and fourth compartment, consisting of 5 membrane

structures-5 function systems, ensuring normal genetic - cell division, information -

response, biosynthetical, bioenergetical, biotransformation functions, also, third

compartment, representing a visceral and external fatty depositions, by using the

computerized Traditional Medical DocAm-1 programm, and at second to establish

the their pathological change by using Modern medicine Diagnostic laboratory tests

at third to establish the coincidence and uncoincidence of Traditional Medical and

Modern medical diagnostic data, at fourth to decide the choosing of appropriate

medicaments, foods, other traditional methods of therapy, basing on the s-NCM new

knowledge as intermediate code between Traditional Medical and Modern medical

diagnostic data, at fifth to decide the principal important quiestion, how to

combined and separately use of medicaments, foods, other traditional methods of

therapy and Modern medicaments, foods.

Graduates - professionals Traditional medical doctors according to standarts MNS

5323 and to ―The job description standard model of medical professionals‖, Minister

of Health order # 442, 2009, www.moh.m is medical proffesiols, who are possessed

the theoretical knowledge, practical skills to conduct prevention, diagnosis, treatment

functions of commonly occurred disease in complience with health care policy in a

first and second step hospitals by combined using Traditional and Modern Medical

methods.

http://www.moh.m/




128

But, appeared last time our new conception as “Substance - external patterns –

abstraction”, “One substance-two medicine”, ―õ + g + S + s-NCM‖ = the solution

of a main urgent problems of medicine is withnessed that between “basic

scientific point of teaching” of Traditional and Modern medicine subjects not

existed any differences.

These differences disappeared in case of using the principally new knowledge

formulated as ―Traditional medical X, G - knowledge + Modern medical S-

knowledge + s-NCM new knowledge = the solution of a main urgent problems of

medicine as ―secrets of normal existence of human body - key cause of pathological

change - their diagnostics - their treatment‖, understand the essence of Traditional

medicine lessons by using the X, G knowledges, understand the essence of Modern

medicine lessons as biochemistry, immunology, physiology by using the S

knowledges, also use them in close context with s-NCM new knowledge by principle

as ―All 80 lessons and one action moment of Diagnosis, treatment of Traditional

medical doctors ―i.e. the cognitive uncoincidence existing between X + G medical

knowledge of Traditional medicine and S knowledge of Modern medicine,relating to

urgent quiestion of medicine as‖ secret of normal existing of human body - key cause

of pathological change - their diagnostics - their treatment ―decided through s-NCM

new knowledge developed, proposed by us, thereby these barriers are demolished.

Such specific therminology firstly developed and proposed by us to express the

essence of integrated medicine and NCM medicine, s-NCM knowledge as ―one cell –

two medicine‖, ―one cell-triple medicine‖, ―The intermediate code between Traditional

and Modern medicine‖, ―Building bridge between Traditional and Modern medicine‖,

―cell related appearance of abstract theory Rlung, mkhris, badgan‖, ―The abstractized

by Rlung, mkhris, badgan model of living cells‖, ―The cell morphophysiological

correlates of abstract theory Rlung, mkhris, badgan‖, also, now started the using by

forein researchers, who are working in the field of integrated medicine.

It should say that the appearance of Integrated medicine, NCM medicine plays the

significant role in the improving the educational process resulting in a Traditional

medical doctor competent at a basic level, in the extending of appropriate foundation

for their further training in any branch of medicine and in increasing the roles of

Traditional medical doctors in the health care system.

One of examples of increasing the roles of Traditional medical doctors in the health

care system is the their participation in genetic study of Traditional medicine,

conducted by Mi Kyeong Lee, Eun-Su Jang, Ho-Young, in the scientific article

―Investigation of Genetic Evidence for Sasang Constitution was written that …―types

in South Korea Sasang constitution type was diagnosed by traditional doctors‖. Leem

KH, Park HK stressed in the article ―Traditional Korean medicine: Now and the

future― (Neurol. Res. 2007, v.29, S3-4): ―If modern medicine provides complement of

Traditional Korean Medicine, it would open up new prospect of research and clinical

regimen for various diseases...‖.

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Leem%20KH%22%5BAuthor%5D



http://www.ncbi.nlm.nih.gov/pubmed?term=%22Park%20HK%22%5BAuthor%5D




129

The all above mentioned things show that now are created the all condition of

implementig the new trend of medical education programm “NCM medical

education in the 21 century, including Traditional and Modern medicines,

connected by new s-NCM knowledge”, aimed to conduct training to preparing

Traditional medical doctors by using full integrated ―X + G + S + s-NCM‖ knowledges

i.e. the training specifics of medical education programm “NCM medical education

in the 21 century, including Traditional and Modern medicines, connected by

new s-NCM knowledge”.

is ―X + G + S + s-NCM‖ full integrated knowledge relating preparing of Traditional

medical doctors.

The specifics of graduates - Traditional medical doctors, trained by program “NCM

medical education in the 21 century, including Traditional and Modern

medicines, connected by new s-NCM knowledge” as follows:

a. Who able to conduct all kinds of prevention, diagnostics and treatment procedures

in case of diseases of Traditional medicine

b. Who able to conduct all kinds of prevention, diagnostics and treatment procedures

in case of diseases of Modern medicine.

c. Who able to analyze all prevention, diagnostics and treatment data of Traditional

and Modern medicine by using s-NCM― knowledges and ―X + G + S + s-NCM‖ full

integrated knowledge and make the final diagnostics and treatment clinical decisions.

In such way the training specifics of medical education programm “NCM medical

education in the 21 century, including Traditional and Modern medicines,

connected by new s-NCM knowledge” meets the ―MNS 5323 standarts‖ demand,

which indicated that… Graduates - professionals Traditional medical doctors is

medical proffesiols, who are possessed the theoretical knowledge, practical skills to

conduct prevention, diagnosis, treatment functions of commonly occurred disease in

complience with health care policy in a first and second step hospitals by combined

using Traditional and Modern Medical methods.

1. Basic membrane states and redoxy potentials of hemolysate, representing

first compartment, containing redoxy line systems in Rlung constitution

category of individuals (Rlung dominated).

All individuals, belonging to Rlung constitution category, identified with help of

DocAm-1 programm parameters, by transferring these parameters to abstract

thermin as as rlung, mkhris, badgan, which not really exist inside of human body,

eventually have a abstract – subjective nature of cognition with a following

differences because of nonexistence of human species as ―Homo sapiens plus rlung,

mkhris, badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan,

yin‖ as if containing the 14 trillion living rlung, mkhris, badgan, yin, yan along with 14

trillion living cells only postulated by Traditional medicine doctors, all their diagnostic




130

and treatment methods based in this form of human specie, but categorically

resisted, refused by NCM medicine.

All individuals, belonging to Rlung constitution category have following

differences:

a. Low Reducing capacity of hemolysate, determined by using the nitroblue

tetrazolium test

b. Low protonizing, radical scavenging activity of hemolysate, determined by using

the Diphenyl picril hydrasyl radical test

c. High Contents of deprotonized products of hemolysate by concentration of TBA

positive products, paralleled with low antioxidant capacity.

2. Basic membrane states and redoxy potentials of all membrane system,

representing fourth compartmemt in Rlung constitution category of individuals (Rlung

dominated).


DocAm-1 programm parameters, obtained these by transferring to abstract thermin

as as rlung, mkhris, badgan, which not really exist inside of human body, eventually

have a abstract - subjective nature of cognition were distinguished by:

a. Low Reducing capacity of of of all membrane system, representing fourth

compartmemt, determined by using the nitroblue tetrazolium test

b. Low protonizing, radical scavenging activity of all membrane system, representing

fourth compartmemt by using the DPPH (2, 2-diphenyl 2 picrylhydrazyl) radical test.

c. High Contents of Deprotonized products of all membrane system,representing

fourth compartmemt, determined by concentration of TBA positive products,

paralleled with low antioxidant capacity.

d. Low contents of saturated and low contents of unsaturated fatty acids contained

in LPHD and LPLD fractions, which incorporated in ―integrated membrane - serum

circultion system‖, which are evidence of prevailing of gamma state of membrane

structures in these indivduals.

i. Low Degree of saturated and also low concentration of unsaturated fatty acids

dependant resistanse of all membrane system, representing fourth compartmemt

are calculated by using osmotic and pereoxidation hemolysis causing test, which are

evidence of prevailing of gamma state of membrane structures in these indivduals.

3. Basic membrane states and redoxy potentials of Redoxy potentials of second

compartment in Rlung constitution category of individuals (Rlung dominated).

All individuals, belonging to Rlung constitution category, established with help of



have a abstract - subjective nature of cognition have following differences:

a. Low redoxy potentials of second compartment of individuals, accounted by

parameters of AO:LPO system, contents of LPHD and LPLD.




131

b. Low reducing capacity of second compartment of individuals established by

using the nitroblue tetrazolium test.

c. Low protonizing, radical scavenging activity of second compartment of individuals

determined by using the DPPH (2, 2-diphenyl 2 picrylhydrazyl ) radical test.

d. High contents of deprotonized products of second compartment of individuals

calculated by concentration of TBA positive products.

e. Low level of concentration of cholesterols, triglycerids and LPHD, LPLD, which are

evidence of prevailing of gamma state of membrane structures in these indivduals.

4. Basic membrane states and redoxy potentials of Redoxy potentials of third

compartment in Rlung constitution category of individuals (Rlung dominated ).

All individuals, belonging to Rlung constitution category, who classified according to



have a abstract - subjective nature of cognition were distinguished by :

a. Low contents of visceral (mainly containing LPLD fraction) and subcutaneous

fatty acids (mainly containing LPHD fraction), which are indicated a prevailance of

membrane - gamma state related low redoxypotentials in these individuals .

Second results:

1. Basic membrane states and redoxy potentials of hemolysate, containing the

first compartment, containing redoxy line systems in Mkhris constitution

category of individuals (Mkhris dominated).

All individuals, belonging to Mkhris constitution category, identified with help of



eventually have a abstract – subjective nature of cognition with a following


mkhris, badgan‖, ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan,





All individuals, belonging to Mkhris constitution category have following

differences:

Low reducing capacity of of hemolysate, accounted by using the nitroblue

tetrazolium test

1. Midlle protonizing, radical scavenging activity of hemolysate, calculated by using

the DPPH (2,2-diphenyl 2 picrylhydrazyl ) radical test.




132

2. High Contents of Deprotonized products of hemolysate by concentration of TBA

positive products, paralleled with high antioxidant capacity.

3. Low Reducing capacity of of of all membrane system, representing fourth

compartmemt, determined by using the nitroblue tetrazolium test

4. Midlle protonizing, radical scavenging activity of all membrane system,

representing fourth compartmemt, determined by using the DPPH (2,2-diphenyl 2

picrylhydrazyl ) radical test.

5. High Contents of Deprotonized products of of all membrane system, consisting of

fourth compartmemt by concentration of TBA positive products, paralleled with low

antioxidant capacity.

6. Low contents of saturated and high concentration of unsaturated fatty acids

contained in LPHD and LPLD, which incorporated in ―integrated membrane - serum

circultion system‖, which are evidence of prevalence of alpha state of membrane


7. Low Degree of saturated and unsaturated fatty acids dependant resistanse of all

membrane system, presenting fourth compartmemt are determined by using osmotic

and pereoxidation hemolysis test, which are evidence of prevalence of alpha state of

membrane structures in these indivduals.

3. Basic membrane states and redoxy potentials of second compartment in

Mkhris constitution category of individuals ( Mkhris dominated ).

All individuals, belonging to Mkhris constitution have following differences:

a. High oxy potentials of second compartment of individuals, accounted by

parameters of AO:LPO system, contents of LPHD and LPLD

b. Low Reducing capacity of second compartment of individuals, established by


c. Midlle protonizing, radical scavenging activity of second compartment of

individuals, calculated by using the DPPH (2,2-diphenyl 2 picrylhydrazyl ) test.

d. High Contents of Deprotonized products of second compartment of individuals

determined by concentration of TBA positive products, paralleled with high


e. Low level of concentration of cholesterols, triglycerid, LPLD and high level of

LPHD, which are evidence of prevailing of alpha state of membrane structures in

these indivduals.

4. Basic membrane states and redoxy potentials of third compartment in

Mkhris constitution category of individuals ( Mkhris dominated).








133

a. Low contents of visceral (mainly containing LPLD fraction ) and high level of

subcutaneous fatty acids (mainly containing LPHD fraction), which are demonstrated

a prevalence of alpha state of membrane structures in these indivduals.

Third results:

All individuals, belonging to Badgan constitution category, identified with help of



eventually have a abstract - subjective nature of cognition with a following


mkhris, badgan,‖ ―Homo sapiens plus vata, kapha, pitta‖, ―Homo sapiens plus yan,





All individuals, belonging to Badgan constitution have following differences:

1. Basic membrane states and redoxy potentials of hemolysate, representing

first compartment, containing redoxy line systems in Badgan constitution

category of individuals (Badgan dominated).

All individuals, belonging to Badgan constitution category, classified with help of



have a abstract - subjective nature of cognition have following differences:

a. High reducing capacity of of hemolysate, accounted by using the nitroblue

tetrazolium test

b. High protonizing, radical scavenging activity of hemolysate, established by using

the DPPH (2,2-diphenyl 2 picrylhydrazyl) test.

c. Low contents of Deprotonized products of hemolysate, determined by

concentration of TBA positive products, paralleled with high antioxidant capacity.

2. Basic membrane states and redoxy potentials of all membrane system, presenting

fourth compartmemt in Badgan constitution category of individuals (Badgan

dominated).

All individuals, belonging to Rlung constitution category, classified with help of



have a abstract-subjective nature of cognition were distinguished by:

a. High reducing capacity of all membrane system, consisting of fourth compartmemt

by using the nitroblue tetrazolium test

b. High protonizing, radical scavenging activity of all membrane system, representing

fourth compartmemt by using the DPPH (2, 2-diphenyl 2 picrylhydrazyl) test.




134

c. Low contents of Deprotonized products of all membrane system, consisting of

fourth compartmemt by concentration of TBA positive products, paralleled with high


d. High contents of saturated and low concentration of unsaturated fatty acids

contained in LPHD and LPLD, which incorporated in ―integrated membrane - serum

circultion system‖, which are evidence of prevailing of betta state of membrane


I. Low degree of saturated and unsaturated fatty acids dependant resistanse of all

membrane system, presenting fourth compartmemt are determined by using osmotic

and pereoxidation hemolysis test, which are evidence of prevailing of betta state of

membrane structures in these indivduals.

3. Basic membrane states and redoxy potentials of second compartment in

Badgan constitution category of individuals (Badgan dominated).

a. High red potentials of second compartment of individuals, accounted by

parameters of AO:LPO system, contents of LPHD and LPLD, which are evidence of

prevailing of betta state of membrane structures in these indivduals.

b. High reducing capacity of second compartment of individuals, determined by


c. Low oxidizing capacity of second compartment of individuals, established by

using the DPPH (2,2-diphenyl 2 picrylhydrazyl) test.

d. Low contents of Deprotonized products of second compartment of individuals,

calculated by concentration of TBA positive products, paralleled with high antioxidant

capacity.

e. High level of concentration of cholesterols, triglycerid, LPLD and low level of

LPHD, which are evidence of prevailing of betta state of membrane structures in

these indivduals.

4. Basic membrane states and redoxy potentials of third compartment in

Badgan constitution category of individuals (Badgan dominated).

All individuals, belonging to Badgan constitution category, classified with help of

DocAm-1 programm parameters, obtained by transferring these to abstract thermin



a. Low contents of visceral (mainly containing LPLD fraction) and subcutaneous

fatty acids (mainly containing LPHD fraction) which are evidence of prevailing of

betta state of membrane structures in these indivduals.

Basing in results of these investigations we conclude that:

1. Inside of every cells existed the regulation, which conducts electron, proton

flow from donators to acceptors, resulting to producing ATP, HADPH, heat




135

energy, ensuring the basis of normal existence of cell and we are given to them

a new thermin as “membrane - redoxy potentials 3 state systems”

2. We observe that, one of ―membrane-redoxy potentials 3 state systems‖ is fluid

alpha state of membrane structures with high degree of oxidation potentials, with

following middle intensity of ATP, HADPH generation and high intensity of heat

energy generation.

3. We observe that, second of ―membrane - redoxy potentials 3 state systems‖ is

solid betta state of membrane structures with high degree of reduction potentials,

with following high intensity of ATP, HADPH generation and middle intensity of heat

energy generation.

4. We observe that, third of ―membrane - redoxy potentials 3 state systems‖ is

intermediate gamma state of membrane structures with low degree of oxidation -

reduction potentials, with following low intensity of ATP, HADPH generation and low

intensity of heat energy generation.

5. We establish that, the fluid alpha state of membrane structures with high degree

of oxidation potentials, with following middle intensity of ATP, HADPH generation and

high intensity of heat energy generates hot, hot oil external patterns and symbolized

in Traditional medicine by hot-fire element and sun like mkhris abstract thermin.

6. We establish that, solid betta state of membrane structures with high degree of

reduction potentials, with following high intensity of ATP, HADPH generation and

middle intensity of heat energy generates cold, cold oil external patterns and

symbolized in Traditional medicine by cold – water, earth element and moon like

badgan abstract thermin.

7. We establish that, intermediate gamma state of membrane structures with low

degree of oxidation - reduction potentials, with following low intensity of ATP, HADPH

generation and low intensity of heat energy generates mobile, light, unoil, cool

external patterns and symbolized in Traditional medicine by mobile - wind element

andwind like rlung abstract thermin.

Summarizing all these results of investigation we develop s-NCM new knowledge,

which expressed as new conception ―The coincidence of Rlung, Mkhris, Badgan

abstract thermin with regulation occurred in membrane - redoxy potentials 3 state

systems of living cells‖.

To elucidate the new knowledge as ―The coincidence of Rlung, Mkhris, Badgan


systems of living cells‖, we are drawn below examples:

A-1 shows electron,protons conductance, B-2 shows proton gradient, formed during

electron, protons conductance, C-3 shows the high energy phosphate - ATP, high

energy electrons-NADPH and heat energy generation with participation of proton

gradient, formed during electron, protons conductance, D-4 shows 5 general

functions, occurred in 5 membrane structure - by using of energy phosphate-ATP,

high energy electrons-NADPH, E-5 shows donators as source of electron, protons, F-




136

6 shows basic acceptors of electron, protons as oxygen, ox forms of NAD, ox forms

of FAD molecules, G -7 shows gamma state of membrane structures with low degree

of oxidation- reduction potentials, solid betta state of membrane structures with high

degree of reduction potentials, fluid alpha state of membrane structures with high

degree of oxidation potentials, H - 8 shows high oxidation potentials state, high

reduction potentials state, low reduction- oxidation potentials state, I-9 shows

membrane – redoxy potentials 3 state lines.

By us established below lawfull processes:

a. In the individuals, coded by Mkhris abstract thermin-in the G-7 point is increased

the fluid alpha state of membrane structures with high degree of oxidation

potentials,because of this in the A-1 point is elevated the electron, protons

conductance, in the B-2 point generated high level of proton gradient, formed during

electron, protons conductance, in the C-3 point occurred high level of heat energy

generation with participation of proton gradient, formed during electron, protons

conductance, in the D-4 point is increased the speed of information-response

reaction, elevated the concentration and synthesis of biological active compounds

with oxidized functional groups, increased the amount of deprotonized products in all

membrane structures, intensified lysosome degradation activity, increased the

quantity of oxygen active forms, observed middle level of protein synthesis,

increased the synthesis of LPHD, decreased the synthesis of LPLD, in the H - 8 point

predominated high oxidation potentials state, in the I-9 point prevailed the fluid alpha

state of membrane structures with high degree of oxidation potentials of membrane –

redoxy potentials 3 state lines, coded by mkhris abstract thermin.

b. In the individuals, coded by Badgan abstract thermin - in the G-7 point is increased

the solid, betta state of membrane structures with high degree of reduction potentials,

because of this in the A-1 point is decreased the electron, protons conductance, in

the B-2 point generated high level of proton gradient, formed during electron,

protons conductance, in the C-3 point occurred high intensity of high energy

phosphate - ATP, high energy electrons-NADPH and middle intensity of heat energy

generation with participation of proton gradient, formed during electron, protons

conductance, in the D-4 point is decreased the speed of information-response

reaction, elevated the concentration and synthesis of biological active compounds

with reduced functional groups, increased the amount of protonized products in all

membrane structures, decreased the lysosome degradation activity, decreased the

quantity of oxygen active forms, observed the high level of protein synthesis,

increased the synthesis of LPLD, decreased the synthesis of LPHD, in the H - 8 point

predominated high reduction potentials state, in the I-9 point prevailed the solid 8

betta state of membrane structures with high degree of reduction potentials of

membrane – redoxy potentials 3 state lines, coded by Badgan abstract thermin .

c. In the individuals, coded by rLung abstract thermin - in the G-7 point is increased

the intermediate gamma state of membrane structures with low degree of oxidation-




137

reduction potentials, because of this in the A-1 point is increased the electron,

protons leak and prevalence of slip potentials, in the B-2 point generated low level of

proton gradient, formed during electron, protons conductance, in the C-3 point

occurred low intensity of formation of high energy phosphate-ATP, high energy

electrons-NADPH and low intensity of heat energy generation with participation of

proton gradient, formed during electron, protons conductance, in the D-4 point is

occurred the hypersensitivity of information-response reaction, decreased the

concentration and synthesis of biological active compounds with oxidized-reduced

functional groups, increased the amount of deprotonized products in all membrane

structures, paralleled with low antioxidant activity, decreased the lysosome

degradation activity, decreased the quantity of oxygen active forms, observed the low

level of protein synthesis, decreased the synthesis of LPLD, decreased the synthesis

of LPHD, in the H - 8 point decreased the oxidation and reduction potentials state, in

the I-9 point prevailed the intermediate, gamma state of membrane structures with

low degree of oxidation - reduction potentials of membrane – redoxy potentials 3

state lines, coded by rLung abstract thermin.

d. In the patients with hyperthyreosis, coded by Mkhris abstract thermin - in the G-7

point is increased the fluid alpha state of membrane structures with high degree of

oxidation potentials, because of this in the A-1 point is elevated the electron, protons

conductance, in the B-2 point generated high level of proton gradient, formed during

electron, protons conductance, in the D-4 point is increased the speed of information

- response reaction, decreased the concentration of cholesteols, LPLD, increased the

concentration of LPHD synthetized here, accumulated in the second compartment,

increased the membrane leakage of all membrane structures, increased the quantity

of deprotonized products in all membrane structures intensified lysosome

degradation activity, increased the quantity of oxygen active forms, in the H - 8 point

predominated high oxidation potentials state, in the I-9 point prevailed the fluid alpha

state of membrane structures with high degree of oxidation potentials of membrane –

redoxy potentials 3 state lines, coded by mkhris abstract thermin .

e. In the patients with hyperthyreosis, coded by Badgan abstract thermin- in the G-7

point is increased the solid, betta state of membrane structures with high degree of

reduction potentials, because of this in the A-1 point is decreased the

electron,protons conductance, in the B-2 point generated high level of proton

gradient, formed during electron, protons conductance, in the D-4 point is decreased

the speed of information - response reaction, elevated the concentration of

cholesteols, protein, LPLD, decreased the concentration of LPHD synthetized here,

accumulated in the second compartment, decreased the membrane leakage of all

membrane structures, increased the quantity of protonized products in all membrane

structures, decreased the lysosome degradation activity, decreased the quantity of

oxygen active forms, in the H-8 point predominated high reduction potentials state, in

the I-9 point prevailed the solid, alpha state of membrane structures with high degree




138

of reduction potentials of membrane – redoxy potentials 3 state lines, coded by

Badgan abstract thermin .

f. In the patients with after hyperthyreosis hypothrophy, coded by rLung abstract

thermin - in the G-7 point is increased the intermediate, gamma state of membrane

structures with low degree of reduction - oxidation potentials, because of this in the

A-1 point is decreased the electron, protons conductance, in the B-2 point generated

low level of proton gradient, formed during electron, protons conductance due to

their leakage and slip mecchanism, in the D-4 point is changed the speed of

information - response reaction, diminished the concentration of cholesteols, protein,

LPLD, the concentration of LPHD synthetized here, accumulated in the second

compartment, increased the membrane leakage of all membrane structures due to

antioxidand shortage, increased the quantity of deprotonized products in all

membrane structures due to antioxidand shortage, increased the lysosome

degradation activity due to elevated membrane leakage, in the H - 8 point

occurredthe lowing of oxidation - reduction potentials capacity, in the I-9 point

prevailed the intermediate, gamma state of membrane structures with low degree of

oxidation - reduction potentials of membrane –redoxy potentials 3 state lines, coded

by rLung abstract thermin.

The establishment of connection with other education organisation and credit

exchange, exchange by experience in the field of preparing of Traditional medical

doctors in the framework of education program ―NCM medical education in the 21

century ,including Traditional and Modern medicines, connected by new s-NCM

knowledge ‖of NCM medicine .

Why we should modify and modernize the education system of preparing of

Traditional medical doctorsin the 21 century,this is because of that :

1. The history of teaching of of Traditional medical doctors had started since 13

century, when many Tibetan medical sutara-books translated in Mongolian language,

through these translation inheritated the the Tibetian style of medical training system,

where prevailed the imagination that human body consists of really existing rLung,

mkhris, badgan, training process of Traditional Medical doctors based in the X, G

knowledge.

In one hand we can say that Traditional medicine (TM) is full system, because TM

has own phillosophy, own founder, TM has own theory, own methods of

investigation, has own methods of prevention, diagnosis, treatment, own methods of

using of all medicaments, own system of preparing of young generation within own

X, G knowledge, but one shortage of TM is that, it have not S and also not s-NCM

knowledge.

2. Frankly speaking in the 21 century the use of medicine, which only based in the X,

G knowledge without S and s-NCM knowledge is impossible, in this case in every




139

day prevention, diagnosis, treatment practice we would feel lack of these

knowledges.

In this connection we are elobarating new medical education program ―NCM medical


by new s-NCM knowledge‖

in which X, G -knowledge of Traditional medicine enriched by Modern medical S-

knowledge and new s-NCM knowledge i.e. X, G knowledge of Traditional medicine

have been integrated with S and s-NCM knowledge, acquiring full character as ―X, G

knowledge + S + s-NCM knowledge‖.

Theoretical basis of new medical education program ―NCM medical education in the

21 century, including Traditional and Modern medicines, connected by new s-NCM

knowledge‖ and ―Traditional medical X, G - knowledge + Modern medical S-

knowledge + s-NCM new knowledge‖ based preparing of Traditional medical doctors

are approved by by results of forein researchers, who are succeded to find rLung -

related genes, mkhris - related genes, badgan - related genes.

Professor Husted C et all (USA, Global Institute for Tibetan Medicine, Norwalk,

California, USA. [email protected])-in own article as Tibetan medical

interpretation of myelin lipids and multiple Sclerosis ( Annals of new York Academy of

sciences, 2009, 1172, 278-296) stressed that ...A comparison of the three humor

theory of Tibetan medicine and the three thermodynamic phase properties of myelin

lipids exemplifies how integrating medical systems can increase understanding of

complex chronic disabling conditions…with citation of our new conception

―Relationship between abstract theory of rlung, mkhris, badgan and membrane -

redoxy potentials 3 state systems‖

The thermin as integrating medical system, expressed by professor Husted C

indicated the essence of our new medical education program ―NCM medical


by new s-NCM knowledge‖

and ―Traditional medical X, G - knowledge + Modern medical S-knowledge + s-

NCM new knowledge‖ based preparing of Traditional medical doctors and gives to

us further collobaration, information change and also possibility of credit change.

Also established by Prasher B et all (Institute of genomics and integrated Biology)

experimetal and clinical data as Triglycerides (TG), total cholesterol, VLDL, LDL,

LDL/HDL ratio was higher in Kapha, who is prone to cardiovascular disease

witnessed the rightness of our similar experimetal and clinical data during which we

observed that the individuals, coded by Badgan abstract thermin - in the G-7 point

is increased the solid, betta state of membrane structures with high degree of

reduction potentials, because of this in the A-1 point is decreased the electron,

protons conductance, in the B-2 point generated high level of proton gradient,

formed during electron, protons conductance, in the C-3 point occurred high intensity

of high energy phosphate-ATP, high energy electrons-NADPH and middle intensity of

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Husted%20C%22%5bAuthor%5d

mailto:[email protected])-in

http://www.ncbi.nlm.nih.gov/pubmed?term=%22Husted%20C%22%5bAuthor%5d




140

heat energy generation with participation of proton gradient, formed during

electron,protons conductance, in the D-4 point is decreased the speed of information-

response reaction, elevated the concentration and synthesis of biological active

compounds with reduced functional groups, increased the amount of protonized

products in all membrane structures, decreased the lysosome degradation activity,

decreased the quantity of oxygen active forms, observed the high level of protein

synthesis, increased the synthesis of LPLD, decreased the synthesis of LPHD, in the

H -8 point predominated high reduction potentials state, in the I-9 point prevailed the

solid 8 betta state of membrane structures with high degree of reduction potentials of

membrane – redoxy potentials 3 state lines, coded by Badgan abstract thermin.

Now in ordr to introduce the new medical education program ―NCM medical


by new s-NCM knowledge‖ and ―Traditional medical X, G - knowledge + Modern

medical S-knowledge + s-NCM new knowledge‖based preparing of Traditional

medical doctors in credit and information change with forein similar education and

research organisations we are planning to establish connection with Bhushan

Patwardhan, India, Director of Institute of Ayurveda and Integrative medicine, Charlie

C. Hu*, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana

46285, Bhavana Prasher,#1

Sapna Negi,#1

Shilpi Aggarwal, Delhi, India 2Department

of Statistics, University of Pune, 411007 Pune, India Bhavana Prasher:

[email protected]; Sapna Negi: [email protected]; Shilpi Aggarwal:

[email protected]; Amit K Mandal: [email protected]; Tav P Sethi:

[email protected]; Shailaja R Deshmukh: [email protected]; Sudha G

Purohit: [email protected]; Shantanu Sengupta: [email protected];

Sangeeta Khanna: [email protected]; Farhan Mohammad:

[email protected]; Gaurav Garg: [email protected]; Samir K

Brahmachari: [email protected]; Indian Genome Variation Consortium: [email protected];

Mitali Mukerji: [email protected], Sanjeev Rastogi ,Vatsala Hospital, Tulsi Das Marg,

Lucknow - 226 004, India. E-mail: [email protected], Si-Woo

Lee,1Republic of Korea. Tel: Phone: +82-42-868-9489; Fax: +82-42-868-9480; E-

mail: [email protected],Yanrui Wua,1, Beijing University of Chinese Medicine, Si-

Woo Lee,1 1

Korea Institute of Oriental Medicine (KIOM), Hyun-Ju Kim, Republic of

Korea 4Department of Oriental Pharmacy, College of Pharmacy, Jong Yeol Kim

1,

National Hospital of Traditional Medicine of Vietnam, 29 Nguyen Binh Khiem St., Hai

Ba Trung Dist., Hanoi, Vietnam and 4Kyunghee University, Department of Sasang

Constitutional Medicine, Kyunghee University Medical Center, 1 Hoegi-dong,

Dongdaemun-gu, Seoul 130-702, Republic of Korea, Bu-Yeo Kim, Seongwon Cha,

Hee-Jeong Jin and Sangkyun Jeong Division of Constitutional Medicine Research,

Korea Institute of Oriental Medicine, 461-24, Jeonmin-dong, Yuseong-gu, Daejeon,

305-811, Korea,

http://www.nature.com/oby/journal/v12/n8/full/oby2004160a.html

mailto:[email protected]


















http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B8H15-50F63T9-3&_user=10&_coverDate=06/30/2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1556320698&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=5669e05c745569d21d80e5b20a6ca6de&searchtype=a

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B8H15-50F63T9-3&_user=10&_coverDate=06/30/2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1556320698&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=5669e05c745569d21d80e5b20a6ca6de&searchtype=a

http://www.hindawi.com/91205435.html






141

Some lecture of professor M.Ambaga, relating to new conception ―Relationship

between abstract theory of rlung, mkhris, badgan and membrane - redoxy potentials

3 state systems‖, s-NCM new knowledge, and the new medical education program

―NCM medical education in the 21 century, including Traditional and Modern

medicines, connected by new s-NCM knowledge ‖ and ―Traditional medical X, G -

knowledge + Modern medical S-knowledge + s-NCM new knowledge‖based

preparing of Traditional medical doctors now are conducted

www.youtube.com/watch .

Now we are informing through internet web site a some new scientific debated

articles as ―The serious mistake revealed by Mongolian researcher professor

Ambaga in one widely in the world used equation‖, ―Rlung, mkhris, badgan - three

states of membrane structures and redoxy potentials‖, ―The one cell – two medicine‖,

new conception and achievements in the field of finding a common language

between Modern and Oriental medicine‖, which at further may be open the way to

extend our connection, credit exchange with foreign similar education and research

organisation in framework of the new medical education program ―NCM medical


by new s-NCM knowledge ‖ and ―Traditional medical X, G - knowledge + Modern

medical S-knowledge + s-NCM new knowledge‖ based preparing of Traditional

medical doctors.



by new s-NCM knowledge‖ able to some analyze the some acute problems of

modern biology and biochemistry by using s – NCM‖ knowledges and ―Traditional

medical X, G - knowledge + Modern medical S-knowledge + s-NCM new

knowledge‖ full integrated knowledge and make the some modified and improved

conclusion i.e. to solve all problems of medicine, relating to the normal existence,

disturbance of normal existence of human body, their diagnosis and treatmen by

using fully membered metabolism equition, which include a G knowledge of

Traditional medicine + X – knowledge of Traditional medicine + S - knowledge of

Modern medicine + s-NCM knowledge of NCM medicine.




142

BASIC METHODS OF INVESTIGATION, CONDUCTED BY US TO CREATING OF

EXPERIMENTAL MODELS OF CELL REGULATION, CODED BY ABSTRACT

RLUNG, MKHRIS, BADGAN THERMINS IN TRADITIONAL MEDICINE

Experimental justification of basic conception of NCM medicine, s-NCM knowledge

and new training technology ―NCM medical education in the 21 century, including

Traditional and Modern medicines, connected by new s-NCM knowledge‖ are

conducted by using following methods.

Subjects of our experimental works was rabbits aged 18-24 months, including male

and female, ratio 50:50.

A. Experimental inducing of fluid alpha states, consisting of unsaturated fatty

acids with high levels of oxy potentials and with high levels of proton, electrons

conductance and high levels heat energy release in a rabbits was caused by injection

of Dinitrophenol 2- 4 (3,5 мg/ kg, four days, under cutaneous)

B. Experimental inducing of solid betta state, consisting of mainly saturated

fatty acids, conditioning a high levels of red potentials and with slow levels of

proton, electrons conductance and low levels of heat energy release, high degree

of energy accumulation and high degree of high energy phosphate-ATP, high energy

electrons in a rabbits was caused by injection of Rotenon (2,5 мg/ kg, four

days,under cutaneous).

Results of our investigation

First results:

A. Change of oxidizing activity of hemaglobine molecules in the first

compartment during of modelling of high alpha state-high oxy potential

elevated situation in rabbits by dinitrophenol (dinitrophenol mediated “proton

loss process”) and their relationship with abstract Mkhris code.

We revealed that in the case of modelling of high alpha state-high oxy potential

elevated situation in rabbits by dinitrophenol (dinitrophenolmediated ―proton loss

process‖) are increased the oxidizing activity of hemaglobine molecules in 3,0-7,67

times in comparision with control animals after 3, 7, 14 days of modelling, which is on

of appearanse of a sun like hot, hot oil external characteristics, coded by abstract

mkhris thermin.

B. Change of reduction: oxidation ratio activity of second compartment (serum

oxidase enzyme activity)during of modelling of membrane high alpha state-

high oxy potential elevated situation in rabbits by dinitrophenol

(dinitrophenolmediated “proton loss process”) and their relationship with

abstract Mkhris code.

By us established that in the case of modelling of high alpha state - high oxy potential





143

process‖) are increased the reduction : oxidation ratio activity of second

compartment (serum oxidase enzyme activity) in 1,2-1,6 times in comparision

with control animals after 3, 7, 14 days of modelling, which is on of appearanse of a

sun like hot, hot oil external characteristics, coded by abstract mkhris thermin.

C. Change of the free radical protonizing activity of membrane - redoxy 3 state

line systems, existing in the first compartment) during of modelling of

membrane high alpha state - high oxy potential elevated situation in rabbits by

dinitrophenol (dinitrophenol mediated “proton loss process”) and their

relationship with abstract Mkhris code.

It was clear that in the case of modelling of high alpha state - high oxy potential


process‖) are slowed the free radical protonizing activity of membrane - redoxy 3

state line systems, existing in the first compartment) in 1,1-1,12 times in comparision

with control animals after 3, 7, 14 days of modelling, which is on of appearanse of a


D. Change of the quantity of deprotonized products in the second compartment

during of modelling of membrane high alpha state - high oxy potential elevated

situation in rabbits by dinitrophenol (dinitrophenolmediated “proton loss

process”) and their relationship with abstract Mkhris code.

We revealed that in the case of modelling of high alpha state - high oxy potential


process‖) are increased the quantity of deprotonized products in the second

compartment in 1, 2 times in comparision with control animals after 3, 7, 14 days of

modelling, which is on of appearance of a sun like hot, hot oil external characteristics,

coded by abstract mkhris thermin.

E. Change of the quantity of deprotonized products in the fourth compartment




It was clear that in the case of modelling of high alpha state - high oxy potential


process‖) are increased the quantity of deprotonized products in the fourth


modelling, which is on of appearanse of a sun like hot, hot oil external characteristics,


I. Change of the quantity of deprotonized products in the fourth compartment




By us revealed that in the case of modelling of high alpha state - high oxy potential





144

process‖) are increased the resistance of membrane structures, belonging to fourth


modelling, which is on of appearanse of a sun like hot, hot oil external characteristics,


Second results:

A. Change of oxidizing activity of hemaglobine molecules in the first

compartment during of modelling of membrane high betta state-high reduction

potential elevated situation in rabbits by rotenone(by blocking cytochrome

oxidase in the complex 4 with elevation of reduced form of NADH) and their

relationship with abstract Badgan code.

We revealed that in the case of modelling of high solid betta state mediated high

reduction potential elevated situation in rabbits by rotenone (by blocking cytochrome

oxidase in the complex 4 with elevation of reduced form of NADH) are decreased the

oxidizing activity of hemaglobine molecules in 1,8-14,0 times in comparision with

control animals after 3, 7, 14 days of modelling, which is on of appearance of a

moon like cold, cool oil external characteristics, coded by abstract badgan thermin.

B. Change of oxidizing activity of hemaglobine molecules in the first


potential elevated situation in rabbits by rotenone (by blocking cytochrome



By us established that in the case of modelling of high solid betta state mediated high



oxidizing activity of hemaglobine molecules in 1,8 -14,0 times in comparision with

control animals after 3, 7, 14 days of modelling, which is on of appearance of a moon

like cold, cool oil external characteristics, coded by abstract badgan thermin.

C. Change of reduction:oxidation ratio activity of second compartment (serum

oxidase enzyme activity) during modelling of membrane high betta state - high

reduction potential elevated situation in rabbits by rotenone (by blocking

cytochrome oxidase in the complex 4 with elevation of reduced form of NADH )

and their relationship with abstract Badgan code.

It was clear that in the case of modelling of membrane high betta state - high

reduction potential elevated situation in rabbits by rotenone(by blocking cytochrome


reduction:oxidation ratio activity of second compartment (serum oxidase enzyme

activity) in 1,6 - 7,25 times in comparision with control animals after 3, 7, 14 days of

modelling,which is on of appearance of a moon like cold, cool oil external

characteristics, coded by abstract badgan thermin.




145

D. Change of oxidizing activity of hemaglobine molecules in the second

compartment during of modelling of membrane high betta state - high


cytochrome oxidase in the complex 4 with elevation of reduced form of NADH)


We observed that in the case of modelling of high solid betta state mediated high



the deprotonized products in the second compartment in 1,2 times in

comparision with control animals after 3, 7, 14 days of modelling,which is on of

appearance of a moon like cold, cool oil external characteristics, coded by abstract

badgan thermin.

E. Change of deprotonized products in the forth compartment during of

modelling of membrane high betta state-high reduction potential elevated

situation in rabbits by rotenone (by blocking cytochrome oxidase in the

complex 4 with elevation of reduced form of NADH) and their relationship with

abstract Badgan code.



oxidase in the complex 4 with elevation of reduced form of NADH ) are decreased

the deprotonized products in the forth compartment in 1,3 times in comparision

with control animals after 3, 7, 14 days of modelling, which is on of appearance of a


I. Change of the free radical protonized activity of membrane - redoxy 3 state

line systems in the first compartment and membrane structures in the forth

compartment during of modelling of membrane high betta state - high


cytochrome oxidase in the complex 4 with elevation of reduced form of NADH)


We observed that in the case of modelling of high solid betta state mediated high


oxidase in the complex 4 with elevation of reduced form of NADH) are increased the

free radical protonized activity of membrane-redoxy 3 state line systems in the first

compartment and membrane structures in the forth compartment in 1,3 times in

comparision with control animals after 3, 7, 14 days of modelling, which is on of


badgan thermin.

L. Change of the resistance of membrane structures, belonging to the forth


potential elevated situation in rabbits by rotenone (by blocking cytochrome




146



It was clear that in the case of modelling of high solid betta state mediated high


oxidase in the complex 4 with elevation of reduced form of NADH) are increased the

resistance of membrane structures, belonging to the forth compartment in 1, 2 times

in comparision with control animals after 3, 7, 14 days of modelling, which is on of


badgan thermin.

M. Change of some parameters in the all 4 compartments during of modelling

of membrane high gamma state-slow redoxy potential situation in rabbits by

long time use of rotenon (by blocking cytochrome oxidase in the complex 4

with elevation of reduced form of NADH) and their relationship with abstract

Badgan code.


reduction potential elevated situation in rabbits by long time use of rotenone (by

blocking cytochrome oxidase in the complex 4 with elevation of reduced form

of NADH) rotenone (by blocking cytochrome oxidase in the complex 4 with elevation

of reduced form of NADH) are increased the contens of LPLD, cholesterols,

triglycerids i.e.decline of dilution effect of LPHD in relation to LPLD, cholesterols,

triglycerids and decreased the contens of LPHD in the the second compartment in

1,2 times in comparision with control animals after 28 days of modelling, which is on

of appearance of a moon like cold, cool oil external characteristics, coded by abstract

badgan thermin.

Third results:

A. Change of some parameters in the all 4 compartments during of modelling

of membrane high gamma state-slow redoxy potential situation in rabbits by

long time use of dinitrophenol (dinitrophenolmediated “proton loss process”)

and their relationship with abstract Rlung code.

We established that in the case of modelling of membrane high gamma state-slow

redoxy potential situation in rabbits long time use of dinitrophenol

(dinitrophenolmediated ―proton loss process‖) are decreased the ATP concentration

by uncoupling process, because of this decreased the ATP-ase activity, leading to

decline of slip redox potential, evidence of these was the decrease of glucose

concentration in the second compartment, decline of concentration of LPLD, LPHD in

1,6 times in comparision with control animals after 14 days of modelling, which is on

of appearance of a wind like unoilly, mobile, light external characteristics, coded by

abstract rlung thermin.

In such way:

1. We observed that in the case of modelling of high alpha state - high oxy potential





147

process‖) are provocated the increase of body temperature, decrease of reduced

form of NADPH contents, increase of oxidized form of NADP contents, oxidizing

activity of hemaglobine molecules, decrease of reduction : oxidation ratio in a first

and fourth compartments, also reduction activity of membrane - redoxy potentials

three state line systems, decrease of membrane resistance of membrane structures

of 1 compartment, elevation of quantity of LPHD in second compartment, increase of

glucose utilization speed in second compartment with following decrease of glucose

concentration in a second compartment, increase of oxidized - deprotonized in a 5

membrane structures, belonging to fourth compartment, exhibiting a sun like hot, hot

oil external characteristics, coded by abstract mkhris thermin.

2. We established that in the case of modelling of high alpha state-high oxy potential


process‖) are increased the quantity of LPHD in a second compartment, decrease of

LPLD, cholesterols, triglycerids in the medium ―between cell membrane structures -

serum, representing a second compartment‖, paralleled with a high alpha state-high

oxy potentials in membrane - redoxy potentials three state line systems, exhibiting a


3. We observed that in the case of modelling of high solid betta state mediated high


oxidase in the complex 4 with elevation of reduced form of NADH) are provocated

the decrease of body temperature, increase of reduced form of NADPH contents,

decrease of oxidized form of NADP contents, deline of oxidizing activity of

hemaglobine molecules, increase of reduction: oxidation ratio in a first and fourth

compartments, elevation of reduction activity of membrane - redoxy potentials three

state line systems, increase of membrane resistance of membrane structures of 1

compartment, decline of quantity of LPHD in second compartment, decrease of

glucose utilization speed in second compartment with following increase of glucose

concentration in a second compartment, decrease of oxidized - deprotonized

products in a 5 membrane structures, belonging to fourth compartment, exhibiting a


4. We observed that in the case of modelling of high solid betta state mediated high



quantity of LPHD in a second compartment, increase of LPLD, cholesterols,

triglycerids in the medium ―between cell membrane structures-serum, representing a

second compartment‖, paralleled with a high solid betta state - high reduction

potentials in membrane - redoxy potentials three state line systems, exhibiting a


b. The change of fourth compartment parameters, consisting of serum and

extracellular system, where donators, acceptors and some metabolites formed in the

result of functioning of 5 membrane structures-5 function systems, ensuring normal




148

genetic - cell division, information - response, biosynthetical, bioenergetical,

biotransformation functions in the form of decrease of contents of donators,

acceptors and some metabolites formed in the result of functioning of 5 of membrane

structures-5 function systems, including synthetic, bioenergy, biotransformation

functions are coded by abstract Rlung code in the Tibetian Mongolian Traditional

medicine.

c. The change of fourth compartment parameters, named as 5 membrane structures

- 5 function systems, ensuring normal genetic-cell division, information - response,



membrane-redoxy potentials three state line systems in the form of decrease of

synthetic, bioenergy, biotransformation functions and of unregulated disturbance of

information - response functions are coded by abstract Rlung code in the Tibetian


d. The change of third compartment parameters in the form of decrease of

visceral and external under skin fatty acids, also donators, acceptors are

coded by abstract Rlung code in the Tibetian Mongolian Traditional medicine.

In such way, the investigation aimed to make the integration between training

programs of curriculum of preparing Traditional medical doctors and interdiscipline

relationship, their inheritance and issue the definition of Rlung, Mkhris, Badgan

abstract thermin, by creating of experimental models of cell regulation, coded by

abstract rlung, mkhris, badgan thermins in Traditional medicine is revealed and

confirmed the scientific basis of new training technology ―NCM medical education in

the 21 century, including Traditional and Modern medicines, connected by new s-

NCM knowledge‖ because during which became clear the essence of the new

conception and new knowledge as ―The coincidence of Rlung, Mkhris, Badgan


systems of 14 trillion living cells.

THE SERIOUS MISTAKE REVEALED BY MONGOLIAN RESEARCHER

PROFESSOR AMBAGA IN ONE WIDELY IN THE WORLD USED BIOCHEMICAL

EQUATION

Over the last 50 years in the world we have been using the incorrect formula as

Donators (glucose - source of protons and electrons) + O2 (acceptor of protons) =

Energy (ATP + heat energy) + H2O + CO2 “ in every Chemistry and Biology hand

manuals starting as of sixth grades in schools.

We say that this formula Donators (glucose - source of protons and electrons) + O2

(acceptor of protons) = Energy (ATP + heat energy) + H2O + CO2 “is completely

incorrect. If it is the case, formation of such end products energy as energy (ATP +

heat energy) + H2O + CO2 would not be occurred, instead of them glucuronic acid




149

and gluconic acid would be formed as a result of oxidation of glucose molecule in the

presence of enzyme glucose oxidase (GOD).

The right variant of this formula should be ―carbohydrate, aminoacids, fatty acids + 3

state line of membrane - redoxy potential as very important place of conducting of

protons, electrons, starting from cyanobacteria formed during last 3,8 billion years +

O2 = energy (ATP + heat) + H2O + CO2‖ by putting the membrane-redoxy three state

chain lines between ―carbohydrate, aminoacids, fatty acids and Î2.

Only in that case energy plus H2O and CO2 would be formed. It was interesting that

the general features of the abovementioned correct variant reaction were described

by the symbolic codes as rlung(vata), mkhris (pitta), badgan (kapha) in Ayurveda-

Tibetian-Mongolian Traditional medical system. In another words, if this reaction

occurred by the first variant, donators as carbohydrate, aminoacids, fatty acids would

be slowly utilized under influence of betta state of membrane structures and

prevailed reduction potentials. It would lead to more conversion of proton gradients to

ATP with less formation of heat energy because of more limitation of proton leak in

the mitochondrial inner membrane. The external features of this reaction are

accompanied by the appearance of cold, heavy, cool-oil external patterns described

in the theory of Tibetan-Mongolian Traditional medicine by symbolic codes as

Badgan-moon, water+earth elements. The another form of the reaction will be its

second variant. If this reaction is occurred by the second variant, then donators as

carbohydrate, aminoacids, fatty acids would be more rapidly utilized because of

sufficient supply of H,e donators as carbohydrate, aminoacids, fatty acids under

influence of alpha state of membrane structures and prevailed oxidation potentials. It

would lead to more conversion of proton gradients to heat energy, with middle

formation of ATP because of relatively high proton leak in the mitochondrial inner

membrane. The external features of this reaction can be shown in the appearance of

hot, light, hot - oil external patterns which are described in the theory of Tibetian-

Mongolian Traditional medicine by the symbolic codes as mkhris – sun and fire

elements. Now it is the third variant. If, it is dominated by the third variant then

donators as carbohydrate, aminoacids, fatty acids would be diminished and the

concentration of O2 would be also decreased under influence of gamma state of

membrane structures and slow redoxy potentials. It would lead to decrease of proton

gradients which are accompanied with low formation of ATP, NADPH, heat energy

because of decrease of mitochondrial inner membrane potential. The external

features of this reaction are the appearance of mobile, light, non-fatty external

patterns, determined in the theory of Tibetan-Mongolian Traditional Medicine by the

symbolic codes as rlung-wind, and wind rlung elements.

Some chapter of book dwells on the philosophical problems of new conception" The

theory of rLung, mkhris, Badgan - membrane - redoxy potentials 3 state line system

of 14 trillion living cells.




150

In the results of using the new methodological appraoch "Inner essence, substance -

various external properties - abstract notion "we came to conclusion, that, in the

theory of TMTM under abstract notion" Mkhris" summarized and symbolized the

existence of secret substance on 14 trillion living cells, which enable to produce hot,

acute, hot oil characteristics - external properties, these according to Oriental

philosophy is formed during functioning of abstract element" fire".

The role of such secret substance on 14 trillion living cells can play the heat-

producing alpha state of membrane structure - one of basic member of




+ CO2‖ full membered reaction medium functioned in 14 trillion cells, because when

this state prevails on MS created the precondition of producing the heat energy and

increasing the functional activity of whole organism, increasing of symphatic nervous

activity of human body, which described in the theory of TMTM as acute, hot, hot oil

characteristics of Mkhris.

Under the abstract notion of " Badgan" summarizes the existence of substance on 14

trillion living cells, which enable to create heavy, cold, cold oil characteristics-external

properties, this according to Oriental philosophy is formed in the results of functioning

of abstract elements " water and earth".

The role of such secret substance can play the energy accumulating, heat limited

solid betta state of membrane structure as one of basic member of ―carbohydrate,

aminoacids, fatty acids 3 state line of membrane - redoxy potential as very important

place of conducting of protons, electrons, starting from cyanobacteria formed during

last 3,8 billion years + O2 = energy (ATP + heat) + H2O + CO2‖ full membered

reaction medium functioned in 14 trillion cells because the predomination of this state

on MS leads to intensify the ATP-synthesis, energy accumulation, increase of body

weight and decrease of the functional activity, increase of parasymphatic nervous

activity of human body, which according to TMTM are symbolized as cold,cold oil,

heavy, stupid characteristics of badgan.

As regard to abstract notion 'rLung", it showes the existence of secret substance on

14 trillion living cells, which enable to create light, mobile characteristics-external

properties, this according to oriental philosophy is formed in the results of functioning

of abstract element "air".

The role of such secret substance can play the gamma state of membrane structure

with low redoxy potentials as one of basic member of ―carbohydrate, aminoacids,

fatty acids + 3 state line of membrane - redoxy potential as very important place of


billion years + O2 = energy (ATP + heat) + H2O + CO2‖ full membered reaction

medium functioned in 14 trillion cells because with participation of this state of




151

membrane occured the process of formation of action potential, propagation of

nervous impoulse, and the appearance of lability property of the excitation process,

which in the theory of TMTM expressed as Light, mobile characteristics of rLung.

Our book deals with contemporary tendency and attempts of other scientists in

explanation to the scientific basis of theoretical problems of TMTM. The main

mistakes and misunderstanding to interpretation of the theory of TMTM is connected

with the exaggeration of whether their abstract side and or only objective material

concrete side i.e. do not given attention to this fact that every abstract notion is based

and formed in the results of perceiving of any really objective substance and it's

external signs. Our new conception and using new methodological approach" Inner

essence, substance-external properties-abstract notion" gives the possibility to

confirm that rLung, Mkhris, Badgan are abstract notion, which is formed during

cognizing of various external functional properties of functioning of three Basic states

of MS by human intellectual ability.

This book is devoted to explanation of scientific essence of these theoretical

formulations, that why in TMTM such different with each to other things as human

age, Individual's body-psychic specificity, seasonal factors, diet, solid organs are

ultimately summarized by only three words as rLung, Mkhris, Badgan.

We set forth:

1. Age-related changes of abstract coded Badgan-Mkhris-rLung is connected with

ontogenic transformation of three basic states of membrane structure as one of basic

member of ―carbohydrate, aminoacids, fatty acids + 3 state line of membrane -



H2O + CO2‖ full membered reaction medium functioned in 14 trillion cells as follows:

from betta state of membrane structure – to alpha state of membrane structure –at

last to gamma state of membrane structure .

2. People, who influenced by rLung (stooped over form, thin dark complexion /have

the inherited gamma state of wholeorganism's membrane structure as one of basic




H2O + CO2‖ full membered reaction medium functioned in 14 trillion cell.

People, which have the Nature of Mkhris (Sharp mind, great pride) possesses the

inherited fluid alpha state of wholeorganism's membrane structure as one of basic




H2O + CO2‖ full membered reaction medium functioned in 14 trillion cell; Those

having the specificity of Badgan /obesity, Large bodies, long life/ have inherited solid

betta state of wholeorganism's membrane structure as one of basic member of




152




+ CO2‖ full membered reaction medium functioned in 14 trillion cell

3. The food / horse and marmot meat, oil/ which increases the mkhris contains more

quantity of unsaturated fatty acids-main constituents of alpha state of membrane

structure as one of basic member of ―carbohydrate, aminoacids, fatty acids + 3 state

line of membrane - redoxy potential as very important place of conducting of protons,


energy (ATP + heat) + H2O + CO2‖ full membered reaction medium functioned in 14

trillion cells, while the diet /cow's and coat's meat, oil/ increases the signs of abstract

coded Badgan notion ,includes more quantity of cholesterol, saturated fatty acids -

main parts of solid betta state of MS.

4. The abstract thermin of " rise of mkhris in autumn season" is connected with

adaptation reaction of living organism to winter cold by increasing the heat-producing

fluid alpha state of membrane structure as one of basic member of ―carbohydrate,



formed during last 3,8 billion years + O2 = energy (ATP + heat) + H2O + CO2‖ full

membered reaction medium functioned in 14 trillion cells, while the abstract thermin

of" rise of badgan in spring season" explained by the appearance of adaptation

reaction to summer high temperature, which occured in the form of increase of

thermostable rigid crystal, energyaccumulating betta state of membrane structure as

one of basic member of ―carbohydrate, aminoacids, fatty acids + 3 state line of




trillion cells .

This book is directed to interpretation of some secretly - expressed key words,

expressions, which are encountered in old manuscripts, sutars.

A. We established that the excessive rigidification of fluid alpha of membrane

structure /MS/ is due to unproper action of dietary, seasonal, medicamental factors

that had described in TMTM as freezing of melted mkhris, while the excessive

fluidization of rigid betta state of MS under influence of abovementioned pathogenic

factors expressed as melting of freezed Badgan.

B. Based on the new conception" The theory rLung, Mkhris, badgan-membrane

structure" we observed that the theoretical notion of TMTM regarding to reason of

fever diseases existed in close relationship with pathologic changes of basic states of

MS. The immature fever is connected with unsufficient, delayed responce reaction of

immunocytes to pathogenic factors which is due to excessive increase of rigid betta

state of their MS. Under notion of fully developed fever summarized in TMTM the




153

pathologic process is due to excessive rise of fluidity alpha state-unsaturated fatty

acids on MS on immunocytes, which leads to activation of phospholipases,

production of endogenic pyrogenes, as various forms of prostaglandins, interieikin-1.

By the thermin of void fever in the theory of TMTM demonstrated the disease's state,

when heat production is extremely increased because of Disturbance of the normal

ratio alpha: betta parts of gamma states of excitable membranes of thermoregultation

center's neurons.

This book concerns on notion of TMTM about taste and power, property of

Medicaments, According to the theory of TMTM, the reason of disease is the

unbalance state between five elements on human organism, the signs of disease is

the change of general characteristics of abstract coded rLung, Mkhris, Badgan. The

theoretical expression of TMTM on taste of medicaments is shown in the presence of

biologically active substances and chemical functional groups in the every

medicaments, which enable to induce the pharmacological effects i.e. correct the

unbalancess of abstract five elements associated abstract coded rLung, Mkhris,

Badgan in human body in connection with normalization of all processes occurred in

the level of ―Carbohydrate, aminoacids, fatty acids + 3 state line of membrane -



H2O + CO2‖ full membered reaction medium functioned in 14 trillion cells also in 4

compartments and in 10 functional systems of human body.

Meanwhile, the theoretical formulation of TMTM about power of medicaments is

connected with biological events which occures between the Medicament's chemical

substances and biomolecules in cell's levels in the form of positive changes of

pathologically disturbanced three basic states of MS and the normalization of the

interaction of membrane - accociated receptors, enzymes with their hormons,

mediators and substrats. In this connection it can be explain that in the theory of

TMTM under notion of power of medicaments summarized in interaction between five

elements, exist on the medicaments and five elements, from which human body is

subjected. As regard to notion of property of medicaments, it is expressed as the

external patterns of normalization of pathological changed functions i.e. it is external

signs of power of medicaments appeared in the form of the change of general

characteristics of abstract coded of rLung, Mkhris, Badgan towards normalization.

This book is devoted to interpretation the molecular membrane mecchanism of pulse

diagnostic's methods of Tibetan - Mongolain Traditional Medicine (TMTM).

The notion of TMTM upon 'healthy pulse" corresponds to normal balance between

three basic states of membrane structure (MS) and to normal equilibrium of activation

and depression of adreno - cholinoreceptors, adenylatcyclase - cholinesterase

enzymes, adrenatin - acethylcholin mediators, which are participated in the regulation

of blood vessel's tonus. While the graduat increase of alpha state of MS, passing

through several points of fluid phasic transition of membrane leads to upsetting the




154

balance of basic states of membrane structure as basic member of ―carbohydrate,



formed during last 3,8 billion years + O2 = energy (ATP + heat) + H2O + CO2‖ full

membered reaction medium functioned in 14 trillion cells, intensification of the energy

metabolism, the oxygen utilization, to activiation of heat production and to

appearance of external pulse patterns in the form of increase of their rapidity, all

these complex events, occured under pathogenic factors in TMTM are expressed as

hot, excessive hot disease pulse.

The increase of betta state of MS under influence of pathogenic factors is occured

through various points of solidphasic transition is caused the weaking of the energy

metabolism, the decreasing of oxygen consumption- heat generation and the slowing

of pulse, and all these complex effects are determined in TMTM as cold and

excessive cold disease pulse.

Also, we reveal that the notion of TMTM on seasonal change of pulse is connected

with processes of intensification of functional activity of * mother - organ", "son -

organ", "friend - organ" and depression of function of "enemy - organ" under

influence of season - related change of whole organism's membrane structure as

one of basic member of ―carbohydrate, aminoacids, fatty acids + 3 state line of




trillion cells.




155

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Documents

definition of ncm medicine

sncm knowledge

sncm new knowledge

traditional medicine

living rlung

compartments of human

modern medicine

formation of protons