institute for genomics & evolutionary medicine igem .pdf · igem in education • certificate...
TRANSCRIPT
Mission
– Our mission is to harness molecular evolutionary knowledge and techniques to advance research and development in biomedicine to biodiversity.
– We are accomplishing this mission by making fundamental discoveries, developing informatics resources, and training the next generation of young scientists.
Evolution
Medicine Genomics
Informatics
iGEM
Mission
• Discovering the Rules of Life– Patterns and processes that have shaped the
blueprint of life (DNA) and diversity of life on earth
•Genes and Genomes•Species
Mission
• Building evolutionary Tools for Life– Predictive models and translational
technologies•Genome Medicine•Biological Diversity
Scholarship impact
18,000
19,000
20,000
21,000
22,000
23,000
20142015
2016
New Citations 2014-2016
Does not include Masatoshi Nei (adjunct professor)
Research support
$-
$500,000
$1,000,000
$1,500,000
$2,000,000
$2,500,000
$3,000,000
FY15 FY16 FY17
$1,171,424
$2,248,543 $2,530,944 *
EXTRAMURAL FUNDING(EXCLUDES SUBCONTRACTS)
All grants are new to Temple (i.e., FY 2015 onwards). Includes only grants coded into ORG 13410
Example Grant Titles
• Diseases– Cancer/Mendelian Diseases
• Evolutionary Bioinformatics of Tumor Profiles• Computational Diagnosis of Non-Synonymous Variations Using
Structural Dynamics
– Complex Diseases• Methods for Evolutionary Informed Network Analysis to Discover
Disease Variation• eQTL Mega-Analysis for Functional Assessment of Multi-Enhancer Gene
Regulation
– Infectious diseases• Modeling Epidemic Infectious Diseases Using Sequence Analysis• Biological Properties Of HIV-1 V3 Evolutionary Variants
Example Grant examples
• Tools– Databases
• TimeTree: Enabling Discoveries Across Disciplines Through a Synthesis of Time-Calibrated Evolutionary Histories
• FlyExpress: Fruitfly gene expression patterns
– Software• Improved Tools for Population Genomics• (Hyphy) Comprehensive, Fast, and User-Friendly Software for
Evolutionary Analysis• (MEGA) Comparative Molecular Sequence Analysis
iGEM in education
• iGEM faculty are educating and training the future workforce.
• We are developing – certificate programs, – participating in masters' and doctoral degree
programs, – offering advanced courses, and – providing one-on-one research mentoring to
• undergraduate, • graduate, and • postgraduate students.
iGEM in education
• CERTIFICATE IN GENOME MEDICINE– This certificate is designed for undergraduate
students to become conversant in state-of-the-art genomics and computational biology approach to study and remedy human diseases.
• BS IN DATA SCIENCE (GENOMICS AND BIOINFORMATICS)– The Bachelors of Science in Data Science with a
concentration in Genomics and Bioinformatics is to prepare the next generation workforce for managing, processing, and analyzing large quantities of data collected in biology and genomics.
Graduate training
• GRADUATE STUDENT TRAINING PORTALS– Innovative web resources highlighting iGEM faculty
expertise in the following areas have been designed and implemented to attract potential graduate students to iGEM:
• EVOLUTIONARY MEDICINE• GENOMIC EPIDEMIOLOGY• POPULATION GENETICS• More to come…
• Designed and implemented Professional Science Masters (PSM) websites– Bioinformatics, Biotechnology, and Bioinnovation
iGEM Members
• Core faculty = 10– 4 New (Kumar, Hedges, Escalante, Pond) – 1 Adjunct Carnell Professor (Nei)– 3 New CCGG (Hey, Liberles, Schraiber) – 2 Existing (Kulathinal, Spigler)
• Others = 40+– Research Faculty = 5– Postdocs = 9– Doctoral students = 7– Undergrads and MS = ~20