My Lab Human or Mouse Affymetrix Gene Expression Experiments

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Affymetrix Human Genome U133 Plus 2.0 ArrayAffymetrix Human Genome U133A ArrayAffymetrix HT Human Genome U133A ArrayAffymetrix Mouse Genome 430 2.0 ArrayAffymetrix Mouse Genome 430A 2.0 Array

Supported Platforms

Samples annotation

Raw data on hard drive

Raw data and samples annotation securely stored and well organized

Step 1 — Safe Storage: your raw files and sample annotation on InSilico DB, recover them when you want

- 100% web-based- Firefox- Chrome- Safari- IE8 and higher

InSilicoDB.com Requirements Grant or removeaccess to collaborators

Store all your data in oneplace online

You can always easily retrieve your data back

Normalization Data Formatting

fRMA:

Modern version of classic/standardRMA algorithm that improves comparison across studies

Data StorageMake Compatible with tools that need no programming

GENE-E

Make Compatible with tools for people who program

Step 2 — Raw data is compiled into a dataset: preprocessed, formatted ready for analysis, sharing, editing sample annotation

Below Process Automatically Performed behind the scenes

Step 3 – Pay 50 € / per sample to activate for analytics

Use “1MONTHTRIAL”coupon and activate for free

You now have accessto the best analysis toolsright from InSilico DBduring one month

Click on activateto unclock the integration with visualization and analyticsthrid-party, free open-source tools

Requirements:- Sign up to GENE-E- Java- Authentication with

InSilico DB username and password

- No installation required

Capabilities- Heatmaps- Differential

expression analysis- Venn Diagrams- Hierarchical

Clustering- Publication grade

figures

Secure Export

Requirements:- Sign up to

Genepattern- No installation

required- Web based

Capabilities- Hundreds of analysis

Modules developed by Broad Institute and

GenePattern comunnity

GENE-E

Secure Export

Step 4 — Analyze and Discover – The best analysis tools are at your fingertips

GSEA

VennDiagrams

Differential Expression Heatmaps

Third-party Analysis Tools are tightly and securely integrated with InSilico DB and require no installation:- They are web-based, eg,

GenePattern- They are run through Java

Web start, which automatically runs a java application on your machine