. 2553

1

2

Acetylcysteine (Fluimucil) 300 mg / 3 ml 5 Ciprofloxacin 200 mg / 100 ml 11 Lincomycin 600 mg / 2 ml 15 Quinine dihydrochloride 600 mg / 2 ml 20

Acyclovir powder 250 mg 5 Clindamycin (Dalacin C) 150 mg/ ml 11 Magnesium sulfate 16 Ranitidine 50 mg/ 2 ml 21

Adrenaline 1 mg/ml 5 Cloxacillin powder 500 mg, 1 g 11 Meropenem (Meronem) powder 1 g 16 Stilamin (Somatostatin) 3000 g 21 Adenosine (Adenocor) 6 mg / 2 ml 6 Dexamethasone 4 mg/ml 11 Methylprednisolone (Solu-medrol) 1 g 16 Streptokinase powder 1.5 mu 21

Antivenom 6 Diazepam 10 mg/ 2 ml 11 Metoclopramide 10 mg/ 2 ml 17 Streptomycin powder 1 g 22

Amikacin 500 mg/ 2 ml 6 Diclofenac 75 mg/ 3 ml 11 Metronidazole 500 mg / 100 ml 17 Sodium bicarbonate 7.5 % in 50 ml 22

Amoxycillin/Clavulonic (Augmentin) 1.2g 6 Digoxin 0.5 mg/2 ml 12 Morphine sulfate 10 mg/ml 17 Sosium valproate (Depakine) 400 mg 22

Aminophylline 250 mg/10 ml 7 Dimenhydrinate 50 mg / ml 12 Moxifloxacin (Avelox) 400 mg/100ml 17 Succinylcholine 500 mg 22

Amiodarone 150 mg / 3 m l 7 Dobutamine 250 mg / 20 ml 12 Multivitamin injection (OMVI) 17 Sulperazone powder 1 g 22

Amphotericin B powder 50 mg 8 Dopamine 250 mg / 10 ml 12 Naloxone o.4 mg/ml 17 Sulprostone (Nalador) 500 g 23 Ampicillin powder 250 mg, 1 g 8 Enoxaparin (Clexane) 40 mg / 0.4 ml 12 Neostigmine 12.5 mg / 5 ml 18 Tazocin 4.5 g 23

Atracurium besylate (Tracium) 50mg/5ml 8 Ertapenem (Invanz) powder 1 13 Netilmicin (Netromicin) 100 mg/ml 18 Terbutaline 0.5 mg / ml 23

Atropine sulfate 0.6 mg/ml 8 Esomeprazole (Nexium) 40 mg 13 Nicardipine 10 mg / 10 ml 18 Tramadol 50 mg / ml 23

Azithromycin powder 500 mg 8 Fosfomycin powder 2 g 13 Nitroglycerin 25 mg / 5 ml 18 Tranexamic acid 250 mg / 5ml 23

Calcium folinate (Leucovorin) 100 mg 8 Furosemide inj 20 mg/ 2ml 12 Octreotide (Sandostatin) 1000 g / 5ml 18 Vancomycin powder 500 mg 24 Calcitonin Salmon 100 iu/ml 9 Furosemide inj (High dose) 250 mg/25ml 13 Omeprazole (Losec) powder 40 mg 19 Vitamin K 2 mg / 0.2 ml 24

Calcium gluconate 1 g / 10 ml (10%) 9 Gentamicin 80 mg/2 ml 13 Oxytocin 10 U/ml 19 Vitamin K 10 mg / 1 ml 24

Cefazolin powder 1 g 9 Haloperidol 5 mg/ ml 14 Paracetamol 300 mg / 2 ml 19 Vitamin C 500 mg in 2 ml 24

Cefotaxime powder 500 mg , 1 g 9 Heparin 25,000 units / 5 ml 14 Parecoxib (dynastat) powder 40 mg 19 Benztropine Mesylate 1 mg/ml in 2 ml 25

Cefoxitin powder 1 g 9 Hydrocortisone powder 100 mg 14 Penicillin G sodium ; powder 1 mu, 5 mu 19 Colistin 150 mg 25

Ceftazidime (Fortum) powder 1 g 10 Hysocine-N-butylbromide 20 mg/ml 14 Pethidine 50 mg / ml 19 Fondaparinux (Arixtra)2.5 mg/ 2.5 ml 25

Ceftriaxone powder 1 g 10 Insulin : RI 15 Pentazocine 30 mg / ml 20 Nadroparin (Fraxiparine)3800 IU/0.4 ml 25

Chloramphenicol powder 1 g 10 Insulin : NPH , Mixtard 15 Phenytoin (Dilantin) 250 mg / 5 ml 20 Ondansetron 4 mg/2ml 25

Chlorpheniramine 10 mg/ml 10 Imipenem (Tienam) powder 500 mg 15 Potassium chloride 20 mEq / 10 ml 20 Insulin : Detemir 25

Chlorpromazine 50 mg in 2 ml 10 Isoproterenol (Isuprel) 0.2 mg / 1 ml 15 Pralidoxime (2-PAM) powder 1 g 20 Tigecycline 50 mg 25

3

1. IV bolus Sterile Water For Injection (SWFI) D5W NSS

2. IV infusion (solvent) D5W NSS Imipenem D5W NSS D5W NSS

3. D5W NSS D5W NSS

4. 5. High Alert Drug High Alert Drug 6. D5W NSS D5W NSS

IM = Intramuscular ( ) D5W = 5% Dextrose in water

IV bolus = Intravenous bolus () NSS = Normal Saline Solution

IV infusion = Intravenous infusion ( SWFI = Sterile Water For Injection

SC = Subcutaneous () NA = No data available

After Reconstitution =

After Dilution = D5W NSS

4

D5W NSS

= =

=

D5W NSS

Acetylcysteine (Fluimucil) injection 5 Amoxycillin/Clavulonic (Augmentin) 1.2g 6 Amiodarone injection () 7 Amphotericin B powder 50 mg 8 Ampicillin

Ertapenem (Invanz) 1 g

8

13

Esomeprazole (Nexium) 40 mg 13 Haloperidol injection 14 Insulin (RI) : Hyperglycemia 15 Meropenem (Meronem) 16 Morphine sulfate 17 Octreotide (Sandostatin) 18 Phenytoin (Dilantin)injection 20 Pralidoxime (2-PAM) 20 Streptokinase 21 Sulprostone (Nalador) 23

5

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Acetylcysteine (Fluimucil) 300 mg / 3 ml

IV infusion : Paracetamol overdose

Acetylcysteine Paracetamol 8 15 .

150 mg/kg in 200 ml D5W 15

50 mg/kg in 500 ml D5W 4 .

100 mg/kg in 1000 ml D5W > 16 .

- 200-1000 ml - - 24 . -

Acyclovir powder (Zovirax) 250 mg

IV infusion : 5 mg/ml

SWFI 10 ml

100 ml 100 ml 1 . 12 . Avoid

()

12 . Avoid

()

Adrenaline 1 mg/ml

IV infusion : refractory hypotension

1-20 g/min 0.1 1 g/kg/min

6 x weight(kg)xdesired dose (g/kg/min) IV infusion rate (ml/hr)

= mg of drug to be added to 100 ml of IV fluid

IV bolus : 1 mg NSS 10 ml 5 10

SC / IM IM

- 1 mg in

250 ml

1 mg in

250 ml

1-10 g/min 1 g/min=15ml/hr 2 g/min=30ml/hr 3 g/min=45ml/hr

- - 24 . 24 .

6

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Adenosine (Adenocor) 6 mg / 2 ml

: IV ( 1-2 ) peripheral line 6 mg 1-2 2 12 mg 3

12 mg ( 12 mg )

(normal saline flush)

central line 3 mg

Antivenom sera

IV : SWFI 10 ml IV 2 ml / min

: 30 ml IV

2 ml/min 6 .

: 50 ml

100 ml IV 2 ml/min 12 .

IV infusion : NSS D5W 1 : 1 1 : 10 ( 1 ml antivenom to 1-10 ml infusion solution) 30 1 .

24 .

Amikacin 500 mg/ 2 ml

IV infusion :

IM

- 100 ml 100 ml 30 60 - - 24 . 2

Amoxycillin/Clavulonic (Augmentin) 1.2g

IV infusion :

IV bolus : SWFI 20 ml

3 4

SWFI 20 ml

100 ml 30-40 20 7 4 .

At 25 C 8-12.5 .

At 5 C

7

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Aminophylline 250 mg/10 ml

IV infusion :

0-6 wk : 5 mg/kg/day , 6wk-1mo: 12 mg/kg/day

6mo-1yr : 15 mg/kg/day

1-9yr : 1 mg/kg/hr

9-12yr , : 0.9 mg/kg/hr

12-16yr : 0.7 mg/kg/hr

: 0.5 mg/kg/hr

// : 0.25mg/kg/hr

IV bolus : Loading 5 mg / kg 20

( 20 -25 mg/min)

- 50 250 ml

1-5 mg/ml

50 250 ml

1-5 mg/ml

- - 24 . -

Amiodarone 150 mg / 3 m l

IV bolus : Loading dose 5 mg/kg 3 ()

IV infusion : Treatment and prophylaxis of ventricular tachycardia and ventricular fibrillation

1 : 300 mg in D5W 100 ml over 30-60 minutes then 600-900 mg in D5W 500 mlover 24 hours.

2 : 1000 mg 24 . 3

1 Rapid loading : 150 mg specifically diluted solution (1.5 mg/ml) over 10 minutes. Follow immediately with the slow loading

infusion

2 Slow loading infusion : 360 mg specifically diluted solution (1.8 mg/ml) at 1 mg/min over the next 6 hours

3 Maintenance infusion : 540 mg of 1.8 mg/ml solution at 0.5 mg/ml over 18 hours. Maintenance infusion is usually continued at

0.5 mg/min for 48 hours to 96 hours or until ventricular arrhythmias are stabilized. May be continued with caution for up to 2 to 3 weeks.

Transfer to oral therapy as soon as feasible.

1 : Dilute 150 mg (3 ml) in 100 ml D5W (1.5 mg/ml)

2-3 : Dilute 900 mg (18 ml) in 500 ml D5W (1.8 mg/ml)

Storage : Use solutions diluted in PVC container within 2 hours;

use those diluted in glass or polyolefin containers within 24

hours.

8

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

- D5W NSS

infusion 2 8 C 2 8 C Amphotericin B powder 50 mg

IV infusion

SWFI 10 ml

500 ml

(0.1 mg/ml)

4 - 6 . 24 . (

)

7 (

)

Ampicillin powder 250 mg, 1 g

IV infusion :

IV bolus : 250 mg, 1 g SWFI 5 7.4 ml

IV 3-5 < 500 mg

10-15

IM : 250 mg, 1 g SWFI 0.9 3.4 ml

SWFI 5 ml

100 ml

()

100 ml 15 30 1 .

(at 27 C) 4 .

(at 5 C)

D5W : 1 .

NSS : 24 .

D5W:4 .

NSS : 5

Atracurium besylate (Tracium) 50mg/5ml

IV infusion :

Initial 9-10 g/kg/min followed by 5-9 g/kg/min IV bolus : Initial dose 0.4-0.5 mg/kg

0.5 1

- 100 ml

(0.5 mg/ml)

100 ml

(0.5 mg/ml)

- - 24 . 24 .

Atropine sulfate 0.6 mg/ml

IV bolus : rapid IV

SC / IM

- - - - - - - -

Azithromycin powder 500 mg

IV infusion

SWFI 5 ml

250-500 ml 250-500 ml 1 . 24 .

(< 30C) - 24 . 7

Calcium folinate (Leucovorin) powder 100 mg

IV bolus : 2 ml

IV infusion :

Bacteriostatic

WFI 5 ml

50 ml 50 ml Over 15 ml or

160 mg/ml 7 - 24 .

(conc.0.06-1

mg/ml)

-

9

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Calcitonin Salmon 100 iu/ml

Osteoporosis, Pagets disease : 100-200 iu/day

SC / IM

Hypercalcemia : 5-10 iu / kg

IV bolus : slow IV 2-4 24 .

IV infusion : NSS 500 ml 6 .

- - 100 6 . - - - -

Calcium gluconate 1 g / 10 ml (10%)

Rapid IV IV infusion

- 1-2 g in

100 ml

1-2 g in

100 ml

30 60 - - 24 . -

Cefazolin powder 1 g

IV infusion :

IV bolus : 1 g SWFI 7.5-10.5 ml 3-5

IM : 1 g SWFI 2.5 ml

SWFI 5 ml

50 100 ml 50 100 ml 30 60 24 . 10 24 . 96 .

Cefotaxime powder 500 mg, 1 g

IV infusion :

IV bolus : SWFI 10 ml 3-5

IM : 500 mg SWFI 2 ml

1 g SWFI 3 ml

SWFI 10 ml

50 100 ml 50 100 ml 30 60 12 .

( 25 C protected

from light)

24 .

(protected

from light)

12 .

( 25 C protected

from light)

24 .

(protected

from light)

Cefoxitin powder 1 g

IV infusion :

IV bolus : SWFI 10 ml 3-5

IM : SWFI 2 ml

SWFI 10 ml 50 100 ml 50 100 ml 30 60 24 . 7

( 5 C) 24 . 7

( 5 C)

10

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Ceftazidime (Fortum) powder 1 g, 2 g

IV infusion :

IV bolus : SWFI 10 ml 3-5

IM : 1 g SWFI 3 ml

SWFI 10 ml

50 100 ml 50 100 ml 30 60 24 . 7

24 . 7

Ceftriaxone powder 1 g

IV infusion :

IV bolus : SWFI 10 ml 2 - 4

IM : 1 g SWFI 3.6 ml

1 g 1%lidocaine without epinephrine 3.5 ml

SWFI 10 ml

50 100 ml 50 100 ml 30 - 60 6 . 24 . 3 10

Chloramphenicol powder 1 g

IV infusion :

IV bolus : SWFI 10 ml 100

mg/ml 1

SWFI

D5W 10 ml

50 100 ml 50 100 ml 30 - 60 30 - 24 . -

Chlorpheniramine 10 mg/ml

IV bolus

IM / SC

- - - - - - - -

Chlorpromazine 50 mg in 2 ml

IV bolus : NSS

1 mg/ml 1 mg/min

0.5 mg/min

IM

- - - - - - - -

11

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Ciprofloxacin 200 mg / 100 ml

IV infusion

- - - 1 . - - - -

Clindamycin (Dalacin C) 300 mg/ 2 ml, 600 mg/ 4ml

IV infusion

IV infusion :

IM

- 300 mg/50ml

600mg/50ml

900mg/100ml

1200mg/100ml

300 mg/50ml

600mg/50ml

900mg/100ml

1200mg/100ml

Over 10 min

Over 20 min

Over 30 min

Over 40 min

- - 16 32 (4C)

Cloxacillin powder 500 mg, 1 g

IV infusion

phlebitis

IV infusion :

IV bolus : SWFI 10 ml 3-5

IM : 500 mg SWFI 2 ml

SWFI 5 ml

100 ml 100 ml 60 24 . 48 . NSS : 24 .

D5W : 8 .

-

Dexamethasone 4 mg/ml

IV infusion :

IV bolus : 1

IM

- 4 -10 mg in 50

ml

4 -10 mg in 50

ml

- - 24 . 2

Diazepam 10 mg/ 2 ml

IV bolus : 2-5 mg /

IM

- - - - - - - -

Diclofenac 75 mg/ 3 ml

IM :

- - - - - - - -

12

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Digoxin (Digoxin) 0.5 mg/2 ml (0.25 mg/ml)

Initial dose : 0.25 0.5 mg

Maintenance dose : 0.125 0.25 mg/day

IV bolus : 4

Digoxin 1 ml (0.25 mg) SWFI / NSS / D5W

4 ml 5

IV infusion :

IM :

- 50 ml - Over 20 min - - 48 .

If conc.

= 2.5 mg/L

-

Dimenhydrinate 50 mg / ml

IV bolus : IV NSS 10 ml

IV 2

IM

- - - - - - 10 -

Dobutamine 250 mg / 20 ml

IV infusion

1 : 1 (Dobutamine 1 mg : Diluent 1 ml)

2 : 1 (Dobutamine 2 mg : Diluent 1 ml)

- 250 ml

250 ml

2-40 g/kg/min - - 24 . -

Dopamine 250 mg / 10 ml

IV infusion

1 : 1 (Dopamine1 mg : Diluent 1 ml)

2 : 1 (Dopamine2 mg : Diluent 1 ml)

- 250 ml

250 ml 1-40 g/kg/min - - 24 . -

Enoxaparin (Clexane) 40 mg / 0.4 ml

SC

- - - - - - - -

13

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Ertapenem (Invanz) powder 1 g

IV infusion :

IM : 3.2 . 1% 2%

lidocaine HCl injection ( epinephrine)

SWFI NSS

10 ml

50 ml 30 6 .

(25 C) 24 .

(5 C) 4 .

Esomeprazole (Nexium) 40 mg

IV bolus : IV 3

IV infusion :

NSS 5 ml - 100 ml 10-30 12 .

(< 30 C) 12 .

(< 30 C) 12 .

(< 30 C) 12 .

(< 30 C)

Fosfomycin powder 2 g

IV bolus : SWFI/ D5W/ NSS 20 ml 5

IV infusion :

SWFI

D5W NSS

20 ml

100 500 ml 100 500 ml 1 2 . 7 - 7 -

Furosemide inj 20 mg/ 2ml

IV bolus : 20 - 40 mg 1-2

IM

- - - - - - - -

Furosemide inj (High dose) 250 mg/25ml

IV infusion :

-

1-2 mg/ml

1-2 mg/ml

4

mg/min

250 mg : 1 .

- - 24 . Avoid

()

Gentamicin 80 mg/2 ml

IV infusion :

IM

- 50-250 ml

1 mg/ml

50-250 ml

1 mg/ml

30 60 - - 24 . -

14

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Haloperidol 5 mg/ ml

IV infusion :

IV bolus : 5 mg/min

IM

- 0.5100 mg

50 100 ml

1-40 mg/hr - - 24 . -

Heparin 25,000 units / 5 ml

IV infusion :

IV bolus : 1-2

SC

- 25,000 U

250 , 500 ml

100 U / ml , 50

U /ml

25,000 U

250 , 500 ml

100 U / ml , 50

U /ml

1000 U / hr

15-18 U/kg/hr

- - 24 . 24 .

Hydrocortisone powder 100 mg

IV infusion :

IV bolus: SWFI / D5W / NSS 2 ml

30

IM : SWFI / NSS 2 ml

SWFI

D5W NSS

2 ml

0.1 1 mg/ml

100 mg in

100 ml

0.1 1 mg/ml

100 mg in

100 ml

20 30 3 (

)

3 (

)

24 . -

Hysocine-N-butylbromide 20 mg/ml

IV bolus: SWFI 3-5 ml 1

SC / IM

- - - - - - - -

15

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Insulin : RI : Actrapid / Humulin R 1000 units / 10 ml

SC / IM / IV bolus

IV infusion :

( Hyperglycemia)

- - 1 Unit : 1 ml

100 Unit in

100 ml

0.05-0.2

Unit/kg/hr

- - 24 . 24 .

Insulin :NPH :Insulatard / Humulin N 1000 units/10 ml

Mixtard 300 units / 3 ml

Mixtard

SC

- - - - - - - -

Imipenem (Tienam) powder 500 mg

IV infusion

- 10 ml

100 ml

10 ml

100 ml

500 mg

20 30

1 g

40 60

4 . 24 . 4 . 24 .

Isoproterenol (Isuprel) 0.2 mg / 1 ml

SC / IM / Intracardiac / IV infusion / IV bolus

26-27

- - - - - - - -

Lincomycin 600 mg / 2 ml

IV infusion :

Deep IM

- 100 ml

<

1 g /100 ml

100 ml

<

1 g /100 ml

1 . - - 24 . -

16

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Magnesium sulfate

10 % 10 ml (1 g)

IV infusion :

IV bolus : 1.5 ml / min

50 % 2 ml (1 g)

IV infusion :

IM

- 1-20 g in

50 1000 ml

1-20 g in

50 1000 ml

Maximum rate

of infusion :

1 -2 g/hr

Maximum dose

should not

exceed 30-40

g/day

- - 60 -

Meropenem (Meronem) powder 1 g

IV bolus : SWFI 20 ml IV 3- 5

IV infusion :

SWFI 20 ml

50 100 ml

50 100 ml 15 30 8 .

(1525 C) 48 . D5W: 3 .

NSS : 8 .

D5W:14 .

NSS : 48 .

Methylprednisolone (Solu-medrol) 1 g

16 ml ( 62.5 mg/ml)

IM

IV bolus : 125 mg : Direct IV 3-15 IV infusion :

125 500 mg 15-30

500-1000 mg > 30

> 1000 mg > 60

spinal cord injury 8 .

30 mg/kg IV bolus over 15 min 45

continuous IV infusion 5.4 mg/kg/hr 23 .

- > 50 ml > 50 ml 48 . - 48 . -

17

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Metoclopramide 10 mg/ 2 ml

IV infusion : > 10 mg

IV bolus : 1-2

IM

- 50 ml 50 ml 15 - - 24 . -

Metronidazole 500 mg / 100 ml

IV infusion

- - - 60 - - - -

Morphine sulfate 10 mg/ml

IV infusion :

IV bolus : SWFI 4 - 5 ml 3-5

SC / IM

- 0.1 1 mg/ml

in D5W

0.810 mg/hr may

increase depending

on pain relief /

adverse effect ;

usual range up to

80 mg/hr

- - NA NA

Moxifloxacin (Avelox) 400 mg/100ml

IV infusion

- - - 60 - - - -

Multivitamin injection (OMVI)

2 1 12 .

Naloxone o.4 mg/ml

IV infusion : high dose

IV bolus / SC / IM

- Naloxone

2 mg

500 ml

( 4 g/ml)

Naloxone

2 mg

500 ml

( 4 g/ml)

The

administration

rate should be

titrated to the

patient s

response

- - 24 . -

18

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Neostigmine 12.5 mg / 5 ml

IV bolus : 0.5 mg /

SC / IM

- - - - - - - -

Netilmicin (Netromicin) 100 mg/ml

IM / IV infusion

- 50 100 ml 50 100 ml 30 60 - - 7 7

Nicardipine 10 mg / 10 ml

IV infusion 1 : 10 1 : 5

1 : 10 Nicardipine 1 mg : Diluent 10 ml

1 : 5 Nicardipine 1 mg : Diluent 5 ml

IV bolus : 1 mg 1-2

- 10 mg:100 ml

10 mg:50ml

10 mg:100 ml

10 mg:50ml

5 15 g/hr - - 24 . -

Nitroglycerin 25 mg / 5 ml

IV infusion 1 : 10 1 : 5

1 : 10 Nitroglycerin 1 mg : Diluent 10 ml

1 : 5 Nitroglycerin 1 mg : Diluent 5 ml

- 250 500 ml

250 500 ml

5 200 g/min - - 48 . 7

Octreotide (Sandostatin) 1000 g in 5 ml Continuous IV infusion :

bleeding gastro-esophageal varices 25 50 g/hr 5

SC

50 g (0.05 mg) = 0.25 ml 100 g (0.1 mg) = 0.5 ml

-

5, 50, 100

g/ml ()

5, 50, 100

g/ml

24 . -

2

24 .

(< 25 C) 24 .

19

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Omeprazole (Losec) powder 40 mg

IV bolus: 2.5

IV infusion :

SWFI 10 ml 90 ml 90 ml 20-30 NA NA 4 . -

Oxytocin 10 U/ml

IV infusion :

IM : Total dose of 10 units after delivery

- 1 ml

1000 ml

1 ml

1000 ml

1-2 milliunit /

min 15-

30

20

milliunit / min

- - - -

Paracetamol 300 mg / 2 ml IM - - - - - - - -

Parecoxib (dynastat) powder 40 mg

IM / IV bolus

NSS 2 ml - - - 12 . - - -

Penicillin G sodium ; powder 1 mu, 5 mu

IM : 100,000 U/ml

IV infusion : 10 mu / day D5W NSS 1-2 infusion

24 . 1/6 1/4

4 6 . 1-2 .

SWFI 10 ml

2 mu/50ml 2.1-6 mu/100 ml

2 mu/50ml 2.1-6 mu/100 ml

1 .

15-30

24 . 7 24 7

Pethidine 50 mg / ml

IV bolus : slowly

IV infusion : 1 mg/ml has been used as a

supplement to a anesthesia ( D5W/NSS)

SC / IM

- - - - - - - -

20

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Pentazocine 30 mg / ml

SC / IM / IV bolus

- - - - - - - -

Phenytoin (Dilantin) 250 mg / 5 ml

IV bolus : 50 mg/min

1-3 mg/kg/min normal saline flush

IV infusion :

- 50-100 ml

(

1-10 mg/ml)

1 .

Maximum rate

50 mg/min

- - 4 .

pH

< 11.5

-

Potassium chloride 20 mEq / 10 ml

IV infusion

- maximum

concentration

40 mEq /Lit

maximum

concentration

40 mEq /Lit

10-20 mEq / hr

40 mEq/hr

- - 24 . -

Pralidoxime (2-PAM) powder 1 g

IV infusion :

IV bolus : pulmonary edema

infusion SWFI

20 ml 5

SWFI 20 ml

100 ml 30

-

-

Quinine dihydrochloride 600 mg / 2 ml

IV infusion : Loading & Maintenance

Loading dose : 20 mg/kg 2 amp D5W/ NSS

500 ml

Maintenance dose : 10 mg/kg 8 . 7 1 amp

D5W / NSS 200 ml

- 200 -500 ml 200 -500 ml Loading dose :

4 .

Maintenance

dose

2 . q 8 hr

- -

-

21

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Ranitidine 50 mg/ 2 ml

Continuous IV infusion :

Intermittent IV infusion : 50 mg D5W / NSS

100 ml drip 15-20

IV bolus : Ranitidine 50 mg D5W NSS 20 ml

5

IM

- 150 mg in

250 ml

(

2.5

mg/ml)

150 mg in

250 ml

(

2.5

mg/ml)

6.25 mg/hr for

24 hr

- - 24 . -

Stilamin (Somatostatin) 3000 g 1. NSS

2. D5W NSS 500 ml

3. 250 g IV bolus + IV infusion 250 g / hr 40 ml IV

3-5 drip

40 ml / hr 11 .

4. 1-2 IV infusion 40 ml/hr

12 .

NSS 500 ml

(6g/ml) 500 ml

(6g/ml) 12 . - - 24 . -

Streptokinase powder 1.5 mu

IV infusion :

D5W or

NSS (prefer)

5 ml

5 ml

50-100

ml

5 ml

50-100

ml

(prefer)

60 - 24 . 8 . 24 .

22

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Streptomycin powder 1 g IV

IM : 1 g SWFI 3.5 4.5 ml deep IM

into large muscle mass

- - - - 48 . 2 - -

Sodium bicarbonate 7.5 % in 50 ml

IV bolus : 2

D5W 1 : 1

Intermittent IV :

D5W 4-8 .

- - - - - - 24 . -

Sodium Valproate (Depakine) 400 mg

IV bolus : 3

IV infusion :

SWFI 4 ml

50 ml

50 ml

60

20

mg/min

- - 24 . -

Succinylcholine 500 mg

IV bolus :

IV infusion : 0.10.2 % (1-2 mg/ml)

D5W / NSS 0.5 10 mg/min

- 250-1000 ml

(1-2 mg/ml)

250-1000 ml

(1-2 mg/ml)

0.5 10 mg/min 24 . -

Sulperazone powder 1 g

IV infusion :

IV bolus : SWFI 3.4 ml 3

IM : SWFI

2% Lidocaine without adrenaline

SWFI

D5W NSS

3.4 ml

16 ml

16 ml 15 60 24 .

15 30 C - 24 .

15 30 C -

23

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Sulprostone (Nalador) 500 g IV infusion : (0.9 % NSS 2 ml)

NSS 2 ml 1 amp

250 ml / 500

ml

100

g/hr ( NSS 250

ml 17 drop

/min)

500

g/hr (80 drop /min)

- - - 12 .

Tazocin 4.5 g

IV bolus : 3-5

IV infusion :

SWFI NSS

D5W

20 ml

50-150 ml 50-150 ml 20-30 12 . 48 . NA NA

Terbutaline 0.5 mg / ml

IV infusion : D5W NSS

Dextrose

SC

- 10 amp

1000 ml

( 5 g/min)

10 amp

1000 ml

(g/min)

10 g/min - - 48 . -

Tramadol 50 mg / ml

SC / IM / IV bolus : 1 ml/min

- - - - - - - -

Tranexamic acid 250 mg / 5ml

IV bolus : 1-2 ( hypotension)

IV infusion : During or after operation, if necessary, 2-10

ampules (2-10 ml) are given by IV drip infusion

IM :

- - - - - - - -

24

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Vancomycin powder 500 mg

Intermittent IV infusion :

Continuous IV infusion : 1-2 g

D5W / NSS

24 .

SWFI

500 mg/ 10 ml

1 g/ 20 ml

500 mg/100 ml > 500 mg / 250 ml

> 2 . 14 14 7 7

Vitamin K 2 mg / 0.2 ml

(Konakian MM Pediatric) 1

Oral : 2 mg 2 mg 4-7 2 mg 4-6

IM : 1 mg (0.1 ml) 2 3

IV bolus : 1 mg

Vitamin K 10 mg / 1 ml (Konakian)

IV bolus : 0.9% NSS D5W ( 30 )

Oral : 0.5 1 ml 8-12 . 2 2 ml

IM :

Vitamin C 500 mg in 2 ml

IV bolus : 100 mg/min (avoid rapid IV injection)

IV infusion : D5W / NSS

IM

- - - - - - - -

25

(Stability)

(Solvent)

(Diluent) After Reconstitution After Dilution

/ D5W NSS

infusion 2 8 C 2 8 C Benztropine Mesylate 1 mg/ml in 2 ml

IM / IV

- - - - - - - -

Colistin 150 mg

IM

Direct IV over 3-10 minutes

Intermittent IV infusion :over 30 minutes

Continuous IV infusion : 24 .

SWFI 2 ml

fluid

fluid

30 - 7 Freshly

prepare and

use within

24 hours

-

Fondaparinux (Arixtra) 2.5 mg / 2.5 ml

SC

- - - - - - - -

Nadroparin (Fraxiparine) 3800 IU / 0.4 ml

SC

- - - - - - - -

Ondansetron 4 mg/2ml

IM / IV

- - - - - - - -

Insulin : Detemir

SC

- - - - - - - -

Tigecycline 50 mg

IV infusion : 50 mg D5W / NSS 100 ml

()

100 mg 2

IV bag for infusion 100 ml

NSS 5.3 ml Or

D5W 5.3 ml

5 ml

NSS

D5W

100 ml 100 ml 30-60 24 .

( 6 .

18 .

IV

bag)

- - 45 .

(

IV bag )

26

Isuprel 0.2 mg/ml (1:5000)

Recommended dosage for adults with heart block, Adams-Stokes attacks and cardiac arrest

Route of Administration Preparation of Dilution Initial Dose Subsequent Administration

Dose Range*

Bolus intravenous

injection

Dilute 1 ml of solution 1:5000

(0.2 mg) to 10 ml with Sodium

Chloride or 5% Glucose injection

0.02 mg to 0.06 mg (1 ml to 3

ml of diluted solution

1:50,000)

0.01 mg to 0.2 mg (0.5 ml to

10 ml of diluted solution)

Intravenous infusion Dilute 10 ml of solution 1:5000

(2 mg) in 500 ml with Sodium

Chloride or 5% Glucose injection

5 g/min (1.25 ml of diluted solution 1:250,000 per

minute)

-

Intramuscular Use solution 1:5000 undiluted 0.2 mg (1 ml) 0.02 mg to 1 mg

(0.1 ml to 5 ml)

Subcutaneous Use solution 1:5000 undiluted 0.2 mg (1 ml) 0.15 mg to 0.2 mg

(0.75 ml to 1 ml)

Intracardiac Use solution 1:5000 undiluted 0.02 mg (0.1 ml)

* Subsequent dosage and method of administration depend on the ventricular rate and the rapidity with which the cardiac pacemaker

can take over when the drug is gradually withdrawn. There are no well-controlled studies in children to establish appropriate dosing;

however, the American Heart Association recommends an initial infusion rate of 0.1 g/kg/min to 1 g/kg/min

27

Recommended dosage for adults with shock and hypoperfusion states

Route of Administration Preparation of Dilution + Infusion rate ++

Intravenous infusion Dilute 5 ml (1 mg) in 500 ml of 5%

Glucose injection

0.5 g to 5 g per minute (0.25 ml to 2.5 ml of diluted solution)

+ Concentrations up to 10 times greater have been used when limitation of volume is essential

++ Rates over 30 g per minute have been used in advanced stages of shock. The rate of infusion should be adjusted on the basis of heart rate, central venous pressure, systemic blood pressure, and urine flow. If the heart rate exceed 110 beats per minute, it may be

advisable to decrease or temporarily discontinue the infusion

Recommended dosage for adults with bronchospasm occurring during anesthesia

Route of Administration Preparation of Dilution Initial Dose Subsequent Administration

Dose Range*

Bolus intravenous

injection

Dilute 1 ml (0.2 mg) to 10 ml with

Sodium Chloride or 5% Glucose

injection

0.01 mg to 0.02 mg (0.5 ml to

1 ml of diluted solution)

The initial dose may be

repeated when nessary.

28