INFECTION AND IMMUNITYVOLUME 42 NUMBER 3 * DECEMBER 1983

J. W. Shands, Jr., Editor in Chief (1984)University of Florida, Gainesville

Phillip J. Baker, Editor (1985)National Institute of Allergy and Infectious Diseases

Bethesda, Md.Edwin H. Beachey, Editor (1988)

VA Medical CenterMemphis, Tenn.

Peter F. Bonventre, Editor (1984)University of Cincinnati

Cincinnati, Ohio

Arthur G. Johnson, Editor (1986)University of Minnesota, Duluth

Stephan E. Mergenhagen, Editor (1984)National Institute of Dental Research

Bethesda, Md.

John H. Schwab, Editor (1985)University of North Carolina, Medical School

Chapel Hill

Michael A. Apicella (1985)John A. Armstrong (1983)Roland Arnold (1984)Joel B. Baseman (1985)Elmer L. Becker (1984)Neil Blacklow (1984)Arnold S. Bleiweis (1984)William H. Bowen (1985)Robert R. Brubaker (1983)Ward Bullock, Jr. (1985)Priscilla A. Campbell (1983)Charles Carpenter (1985)Bruce Chassy (1984)John 0. Cisar (1985)John Clements (1985)Myron Cohen (1984)Barry C. Cole (1984)Gerald A. Cole (1983)R. John Collier (1984)Lynette Corbeil (1984)Jim E. Cutler (1984)Peter C. Doherty (1984)Judith E. Domer (1983)James L. Duncan (1985)Dennis Dwyer (1984)Roman Dziarski (1984)Robert A. Eisenberg (1984)Barry Eisenstein (1985)Toby Eisenstein (1984)Peter Elsbach (1983)Stanley Falkow (1985)John J. Farrar (1985)John C. Feeley (1985)

EDITORIAL BOARDRobert Finberg (1984)John R. Finerty (1984)Thomas J. Fitzgerald (1983)Samuel B. Formal (1983)Robert M. Friedman (1983)John Gallin (1985)Peter Gemski (1985)Robert Genco (1985)Ronald J. Gibbons (1985)Frances Gillin (1984)Mayer B. Goren (1985)Harry Greenberg (1985)Frank Griffin (1984)Carlton L. Gyles (1985)Edgar Hanna (1984)David Hentges (1985)Martin S. Hirsch (1985)Randall K. Holmes (1983)Dexter H. Howard (1985)Howard M. Johnson (1985)Karl M. Johnson (1983)Russell C. Johnson (1985)William Johnson (1985)Garth W. Jones (1984)Irving G. Kagan (1983)Dennis L. Kasper (1985)George E. Kenny (1984)David F. Keren (1985)George S. Kobayashi (1983)Yi-chi M. Kong (1983)Julius P. Kreier (1983)Maurice J. Lefford (1984)Thomas Lehner (1983)

Stephan H. Leppla (1985)Jack P. London (1983)Michael Loos (1984)John Mansfield (1985)Zell A. McGee (1985)Jerry R. McGhee (1985)Douglas D. McGregor (1985)Floyd C. McIntire (1985)Monte Meltzer (1983)Jiri Mestecky (1983)J. Gabriel Michael (1983)George Miller (1983)W. E. C. Moore (1983)Page Morahan (1985)David Morrison (1983)Frederick A. Murphy (1985)George Naff (1983)Neal Nathanson (1984)Robert J. North (1985)Alois H. Nowotny (1983)Alison O'Brien (1985)Pearay L. Ogra (1983)Roy C. Page (1985)Chik H. Pai (1985)Monique Parant (1984)Fred Rapp (1983)John B. Robbins (1983)Donald Robertson (1984)Burton Rosan (1983)Noel R. Rose (1983)Jon A. Rudbach (1984)Stephen W. Russell (1985)R. Bradley Sack (1983)

Catherine Saelinger (1984)Edward J. St. Martin (1985)Irvin E. Salit (1983)Anthony J. Sbarra (1984)Charles F. Schachtele (1985)Julius Schachter (1983)Jerome L. Schulman (1985)H. Jean Shadomy (1983)Alan Sher (1984)Gerald D. Shockman (1983)Philip Smith (1985)Ralph Snyderman (1985)H. G. Stevens (1985)Barnet M. Sultzer (1985)Catharina Svanborg-Eden (1985)John L. Swanson (1984)Diane Taylor (1984)Ivo van de RUn (1984)Johannes van Houte (1985)Jan T. Vilcek (1985)Stefanie Vogel (1985)Duard L. Walker (1983)Peter A. Ward (1985)Robert G. Webster (1983)William P. Weidanz (1984)William 0. Weigle (1984)Emilio Weiss (1983)Jerry A. Winkelstein (1984)Alex J. Winter (1983)Meyer J. Wolin (1984)David J. Wyler (1984)Wendell D. Zollinger (1985)

Helen R. Whiteley, Chairman, Publications BoardLinda M. Ilig, Managing Editor, Journals

Walter G. Peter III, Director, PublicationsKaren Simon, Production Editor

Infection and Immunity (ISSN 0019-9567), a publication of the American Society for Microbiology, 1913 I St., NW,Washington, DC 20006, is devoted to the advancement and dissemination of fundamental knowledge concerning: (i) infectionscaused by pathogenic bacteria, fungi, and unicellular parasites; (ii) the ecology and epidemiology of pathogenic microbes; (iii)virulence factors, such as toxins and microbial surface structures; (iv) nonspecific factors in host resistance and susceptibility toinfection; and (v) immunology of microbial infection. Instructions to authors are published in the January issue each year;reprints are available from the editors and the Publications Office. Infection and Immunity is published monthly, and the twelvenumbers are divided into four volumes per year. The nonmember subscription price is $225 per year; single copies are $20. Themember subscription price is $37 (foreign, $44 [surface rate]) per year; single copies are $7. Correspondence relating tosubscriptions, reprints, defective copies, availability of back issues, lost or late proofs, disposition of submitted manuscripts, andgeneral editorial matters should be directed to the ASM Publications Office, 1913 I St., NW, Washington, DC 20006 (area 202833-9680).

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Author IndexAbrass, Christine K., 876Achtman, Mark, 907Apicella, Michael A., 1020Ascher, Michael S., 887Aurelian, L., 955

Babu, Uma M., 1013Balber, Andrew E., 869Barnett, Eugene V., 876Berman, Monique A., 887Bhakdi, Sucharit, 1055Bhutani, L. K., 890Bick, P. H., 853Bistrian, Bruce R., 997Black, William J., 980Blackburn, George L., 997Boros, Dov L., 882, 1116Braude, Abraham I., 1109Brook, Itzhak, 986Brooks, Geo. F., 980Brown, Thomas A., 1041Bukholm, Geir, 1198Burdash, N. M., 1020Butler, Gary H., 1136Byrne, Gerald I., 1152

Caldwell, M. Blake, 1176Cannon, Janne G., 980Cantey, J. R., 1020Carpenter, A. B., 853Castleman, W. L., 1159Charnetzky, Willard T., 1092Chedid, Louis, 1081Chensue, Stephen W., 1116Claflin, J. Latham, 1041Clegg, Steven, 900Cohen, Mark, 936Colburn, Keith K., 876

Darveau, Richard P., 1092Davis, Charles E., 1109Degre, Miklos, 1198Dinarello, Charles A., 997Douglas, Herndon, 1109

Eaton, Linda J., 1034Etherden, I., 1006

Farr, Barry, 1195Finkelstein, Richard A., 990Friedman, H., 1187Fujii, Yoshio, 1183

Gaafar, Hassan A., 1126Galelli, Anne, 1081Gamon, Lindsay B., 1168Ghadirian, E., 1017Gibbons, R. J., 1006Gleason, R. Roger, 965

Golde, David W., 876Green, Bruce A., 924Grimwood, Brian, 1126Guenounou, Moncef, 1049Gwaltney, Jack M., Jr., 1195

Habig, William H., 942Hall, C. E., 1159Hampar, Berge, 1067Hancock, Robert E. W., 1027,

1092Hardegree, M. Carolyn, 942Hayden, Frederick G., 1195Higashi, Gene I., 1116Holmes, Randall K., 914, 924Hurlbert, Ronald E., 1092

Isibasi, Armando, 949Iwasaka, T., 955

Jacobson, R. H., 1159Jennings, Harold, 936Jimenez, Enedina, 949

Kamen, Paul R., 1191Kenimer, James G., 942Kenney, Howard M., 876Kihlstrom, Erik, 930Koff, Wayne C., 1067Kongshavn, P. A. L., 1017Kroll, Hein-Peter, 1055Krueger, David A., 1152Kulakowska, Malgorzata, 1086Kumate, Jesus, 949Kunkel, Steven L., 1116

Leon, Ofra, 1144Levine, R. P., 907Lipscomb, Mary F., 965Lugowski, Czes}aw, 1086Lyons, Clifford R., 965

Mandell, Gerald L., 1195Masterson, Robert, 973Mayden, Jan, 907McBride, Barry C., 1073McGarrity, Gerard J., 1168McLaughlin, C. A., 1159Meerovitch, E., 1017Megraud, Francis, 1168Meredith, M. P., 1159Mestecky, Jiri, 1041Moldawer, Lyle L., 997Moreno, E. C., 1006Morris, E. Jane, 1073Mutharia, Lucy M., 1027

Nachamkin, Irving, 980Nagahama, Masahiro, 1183Nath, Indira, 890Nauciel, Charles, 1049Newland, John W., 924Niederhuber, John E., 882Nugent, Kenneth M., 1102

O'Connor, Gerald, 1126

Palcanis, K. G., 853Panos, Charles, 1144Pesanti, Edward L., 1102Pier, Gerald B., 936Pierce, Jennie K., 900Pluschke, Gerd, 907Prato, Catherine, 863

Rest, Richard F., 1034Rodrick, G. E., 1187Rogers, James E., 1176Rogolsky, Marvin, 973Romanowska, Elibieta, 1086Russell, Michael W., 1041

Sakurai, Jun, 1183Sathish, M., 890Schaffner, Andreas, 1109Schook, Lawrence B., 882Schroer, Kenneth, 1041Sciortino, Carmen V., 990Seniff, Donna A., 1067Sharma, A. K., 890Sheridan, J. F., 955Showalter, Stephen D., 1067Sippel, John E., 863Sobrado, Javier, 997Soderlund, Gustaf, 930Specter, S., 1187Stanbridge, Eric J., 1136Stein-Streilein, Joan, 965Stewart, Shannon D., 1176Sturtevant, Joy E., 869Sugasawara, Renee J., 863, 980Sully, E. C., 853Sweet, Richard L., 980

Tamplin, M. L., 1187Taylor, Peter W., 1055Tomlinson, Karen, 1144Twiddy, Edda M., 914

Vacheron, Frangoise, 1049Verstreate, D. R., 1159Von David, William, 973

Walker, Richard I., 986, 1176Ward, Peter A., 1116Weisbart, Richard H., 876Wellhausen, Samuel R., 882

West, Timothy E., 1020Wiley, Bill B., 973Williams, Jim C., 887Winter, A. J., 1159

Yeakel-Houlihan, Darlene, 965

Zeiger, Allen R., 1013

ACKNOWLEDGMENTThe following have served as invited special reviewers for Infection and Immunity during 1983, and

their help is greatly appreciated.

Soman AbrahamWilliam AdlerJulia AlbrightJohn F. AldereteHenry AldrichAnton AllenRobert C. AllenAnthony AllisonLeonard C. AltmanPorter AndersonFaustus G. AraujoDonald ArmstrongStephen S. AmnonFrancoise AudibertRobert AustrianElia AyoubCarol J. BakerEdward BalishMichael F. BarileW. Lane BarksdaleAlmen L. BarronJohn B. BartlettPhilip BassfordRobert E. BaughnBlaine BeamanLloyd BeckWilliam R. BeiselJames E. C. BellamyMerlin S. BergdollRaymond J. BergeronRichard S. BerkL. Joe BerryGary K. BestAnn BjornsonJ. E. BlalockMartin BlaserDonald L. BornsteinMichael BoyleJohn J. BozzolaS. Gaylen BradleyJ. C. BrownH. Curt BubelJ. J. BullenW. BurgdorferGerald I. ByrneJanne CannonJoseph R. CanteyAndre CapronMary M. CarruthersGail H. CassellK. P. ChangSotiros ChaparasMerrill W. ChaseLouis A. ChedidAlan CheeverPriscilla ChenC. P. CheneyBruce CheseboroGordon D. ChristensenJoseph E. CiardiJames A. ClagettWilliam B. Clark

Steven CleggWallace A. ClydePhilip CohenMichael F. ColeDaniel G. ColleyAlbert M. CollierFrank CollinsMichael F. CollinsRita ColwellJohn W. CostertonCharles D. CoxRebecca A. CoxGeorge CozadJohn R. CraigD. E. CravenJorge H. CrosaAlan CrossRoy Curtiss IIIJames DaleWalter S. DallisB. Das GuptaPhillip DaviesC. P. DavisFritz DeGraafWalter DempseyDickson D. DespommierLouis DiamondR. D. DiamondHugh C. DillonCharles A. DinarelloJoseph H. DirienzoJacob A. DonkerslootSam DontaStephen D. DouglasR. J. DoyleThomas DrakeRockford K. DraperDonna DuckworthHerbert L. DupontDavid DurackLeon EidelsRichard P. EllenJerrold J. EllnerAlfred F. EsserKlaus M. EsserMax EssexElsie M. EuguiDolores EvansJay FarrelR. FayerRobert FeketyGerald W. FernaldMichael FieldDavid FinbloomSidney M. FinegoldRichard A. FinkelsteinDavid FitzgeraldJames D. FoldsAnne H. FortierAlvin FoxCarl E. FraschDouglas Fraser

Rolf FreterMichael G. GabridgeOthmar GabrielChris GalanosJames R. GanawayTheresa L. GerrardHenry GewurzRalph'A. GiannellaRay GildenJohn B. GingrichWarner GoebelIrving GoldschneiderNicholas K. GonatasF. Gonzalez-ScaranoHarry GooderSherwood GorbachEmil GotschlichRichard GreenbergSidney E. GrossbergGunter GruppRichard L. GuerrantBernard GuggenheimLucien B. GuzeNortin HadlerC. G. HaidarisStephen L. HajdukSeymour P. HalbertThomas L. HaleSeong HamIan R. HamiltonE. HandmanEric J. HansenPaul H. HardyLiana HarvathThomas P. HatchAndreas H. W. HauschildWilliam HauswirthA. HeleniusRonald B. HerbermanHerbert B. HerscowitzErik HewlettBill HildemanAnthony E. HilgerHarry R. HillMaurice HillemanLillian HoldemanKing L. HolmesJan R. HolmgrenB. M. HonigbergClaude I. HoodJames G. HowardRichard J. HowardRussell HowardM. HoweVirgil HowieEric HunterKenneth W. Hunter Jr.Vincent IaconoJohn J. landoloBarbara IglewskiMasayori InonyeRichard E. Isaacson

Robert W. JacksonGeorge JakabStephanie JamesJames B. JensenMary K. JohnsonJeffrey M. JonesHarold V. JordanRalph F. KampschmidtFrank KapralMorris J. KarnovskyPaul KatzStephen P. KatzDavid KeisterJan KeithlyFilipe KierszenbaumSeymour KlebanoffPer KlemmFrederick A. KlipsteinFloyd C. KnoopArthur KochKenneth S. KornmanArnold S. KregerRaymond E. KuhnSteven L. KunkelCho Chuo KuoHoward K. KuramitsuCarl LamannaJean LanghorneDonald J. LeBlancRobert I. LehrerSamuel LehrerMyron LevinMichael LevineLaney LevyCalvin C. LinnemannThomas F. LintRosemary LinzerJames M. LiptonMax A. ListgartenWalter J. LoeschMichael A. LovettWilliam LuttgeWerner K. MaasHunein F. MaasabP. Helena MakelaCharles R. ManclarkDennis F. ManganRalph MartinezHenry MasurCarl F. T. MatternK. P. W. J. McAdamWilliam P. McArthurRaymond A. McBrideMaclyn McCartySuzanne M. MichalekJohn MiddlebrookJames N. MillerLouis MillerRobert MisbinThomas J. MoehringRoland MollbyHarley W. MoonRobert MoonVernon L. MooreRandal E. MorrisStephen A. MorseSteve L. Moseley

Stephen MoserJames W. MoulderRichard MoxonJohn J. MunozDonna MurasakoJohn R. MurphyPatrick MurphyHenry W. MurrayDaniel M. MusherQuentin N. MyrvikCarol NacyRonald L. NagelCarl F. NathanHiroshi NikaidoSigurd NormannRuth S. NussenzweigItzhak OfekJames OliverRonald OlsenSjur OlsnesAndrew B. OnderdonkRichard A. OrmsbeeJoseph V. OstermanEric OttesonD. PappagianisDavid ParetskyMichael ParizaCharlotte ParkerP. J. PatelP. A. PatteeWilly F. PeissensRonald P. PelleyJames E. PenningtonJohnny W. PetersonPhillip K. PetersonSem H. PhanLarry K. PickeringNathan PiercePeter G. W. PlagemannA. G. PlautStanley A. PlotkinMatthew PollackLeonard W. PoulterDavid G. PritchardRichard A. ProctorGeorge W. PughPaul G. QuieH. V. RaffReuben RamphalKenneth H. RandRichard RanneyMrinalini C. RaoRuth S. RappaportRobert ReidMichael F. ReinNeil E. ReinerJack S. RemingtonRichard F. RestJudy RhodesRoberta L. RichardsStephen H. RichardsonMarilyn C. RobertsMichael RobertsJennifer RojkoYvonne T. RosenbergDavid RosenstreichSara Rothman

David SacksAnn L. SandbergMerle A. SandeLouis D. SaravolatzDwayne C. SavagePatrick M. SchlievertJon R. SchmidkeCarl A. SchnaitmanGary SchoolnickPhillip ScottJohn R. SeedJohn A. ShaddSmith ShadomyWilliam ShaferCharles C. ShepardPatricia L. ShipleyCharles W. ShusterFrederic J. SilverblattLance L. SimpsonW. A. SimpsonReuben P. SiraganianEmil SkameneRobert C. SkarnesJ. SlotsDonald W. SmithH. Williams SmithJanet SmithIrvin SnyderMaggie SoSigmund S. SocranskyFrederick SparlingWilliam M. SpiraPaul StevensBruce StockerSusan StraleyThomas StricklandHiroshi SugiyamaNorton A. TaichmanMartin A. TaubmanGail A. TheisM. J. ThomassenJohn ThompsonMichael ThompsonKenneth TimmisChou-Chik TingAlexander TomaszWilliam TragerEdmund TramontThomas M. TrischmannElaine TuomanenJohn TurkJay UnkelessJames VaraniFranz C. Von LichtenbergSharon M. WahlPeter D. WalzerJohn R. WarrenRich WarrenJames D. WatsonSusan WatsonLawrence G. WayneNorman WeatherlyWarner S. WegenerWilliam 0. WeigleEugene D. WeinbergAlison A. WeissJerrold Weiss

Rod WelchWilliam D. WelchMichael W. WesselsHelen N. WestfallL. J. WheatRobert W. WheatTracy Wilkins

Hazel WilkinsonJim C. WilliamsPeter H. WilliamsM. C. WillinghamHerbert H. WinklerWashington WinnCharles L. Wisseman

Charles L. WittenbergerPriscilla WyrickWilliam W. YotisWilliam J. YountElizabeth ZieglerRichard J. ZieglerCharles H. Zierdt

AUTHOR INDEX

VOLUME 42

Abramczuk, Jan, 301Abrass, Christine K., 876Achtman, Mark, 907Acres, S. D., 653Adams, Cynthia B., 585Allen, Janice B., 796Allison, Anthony C., 385Ameglio, F., 122Anderson, Lawrence W., 845Andre, F. E., 599Apicella, Michael A., 1020Ascher, Michael S., 887Aurelian, L., 955Azadegan, Ali A., 42Azuma, Masanobu, 567

Babiuk, L. A., 106Babu, Uma M., 1013Baccarini, M., 1Badger, Shirley J., 208Baek, Leif, 88Baker-Zander, Sharon A., 634Baklaic, Z., 599Balber, Andrew E., 869Barenkamp, Stephen J., 257Barnett, Eugene V., 876Baruch, D., 133Baseman, Joel B., 623Baughn, Robert E., 579, 585Berger, Melvin, 594Berka, Randy M., 276Berman, Monique A., 887Bhakdi, Sucharit, 1055Bhutani, L. K., 890Bick, P. H., 853Binn, Leonard N., 418Bistoni, F., 1Bistrian, Bruce R., 997Bjorck, Lars, 326Bjorn, Michael, 48Black, William J., 980Blackburn, George L., 997Blaser, Martin J., 276Blom, Jens, 308Boesman-Finkelstein, Mary, 639Bohach, Gregory A., 318Bolton, Veronica, 605Booth, Barbara A., 639Boros, Dov L., 882, 1116Bottone, Edward J., 414Bowen, W. H., 431Bowie, James U., 76Brade, Helmut, 250Bradley, S. G., 645Bramucci, Michael G., 427Braude, Abraham I., 1109Bray, B., 653Breuer, W. V., 133Brintzenhofe, Karen L., 394

Bronson, R. T., 783Brook, Itzhak, 986Brooks, Geo. F., 980Brown, Eric J., 594Brown, John C., 683Brown, Lee R., 716Brown, Thomas A., 1041Buening, Gerald M., 15Bukholm, Geir, 1198Burdash, N. M., 1020Burmeister, J. A., 510Butler, Gary H., 1136Byrne, Gerald I., 1152

Cabantchik, Z. I., 133Calandra, Gary B., 7%Caldwell, M. Blake, 1176Camargo, Ena, 81Cannon, Janne G., 980Cantey, J. R., 1020Capobianchi, M. R., 122Carlson, Eunice, 285Carpenter, A. B., 853Carson, C. Andrew, 15Castleman, W. L., 1159Cato, E. P., 510Ceri, Howard, 574Cerutti, Italina, 728Chan, Lydia, 170Chanock, Robert M., 81Chany, Charles, 728Charnetzky, Willard T., 1092Chaudhary, Subhash, 818Chedid, Louis, 1081Chensue, Stephen W., 1116Cianciotto, Nicholas, 48Cisneros, R. L., 783Claflin, J. Latham, 1041Clark, H. Fred, 293Clark, Richard B., 414Clawson, C. Carlyle, 394Clegg, Steven, 900Clements, Janice R., 333Cohen, Mark, 936Cohen, Stuart H., 605Colburn, Keith K., 876Costerton, J. W., 88Couch, Robert B., 453Cunningham, Madeleine W., 531Curtis, M. A., 431Curtiss, Roy, III, 558

Darveau, Richard P., 170, 1092Davis, Charles E., 1109de Graaff, Johannes, 245de Jong, Jan A., 187Degre, Miklos, 1198Devoe, Irving W., 471Dillman, Richard C., 350

Dinarello, Charles A., 997Dodd, Douglas C., 333Dolei, A., 122Donaldson, Stephen L., 487Doring, Gerd, 197Douglas, Herndon, 1109Dreyfus, Lawrence A., 539Drutz, David J., 374

Easmon, Charles S. F., 71Eaton, Linda J., 1034Ebersole, J. L., 156Ebersole, Jeffrey L., 668Echeverria, Peter, 152Eiklid, Kristin, 771Eisenstein, Barry I., 333Ellis, William G., 409Ellwood, D. C., 19Endo, Nobuko, 618Engert, Richard F., 838Escamilla, Joel, 152Etherden, I., 1006

Falkow, Stanley, 33, 178Fang, Z.-Y., 402Farr, Barry, 1195Fedorka-Cray, P. J., 501Fields, Bernard N., 301Filion, L. G., 106Finkelstein, Richard A., 639, 990Fleischmann, Jacob, 10Flores, Jorge, 835Frank, Michael M., 594Frantz, Joseph C., 539Friedman, H., 1187Friedman, Herman, 421Friedman, Michelle, 421Frisch, Carolyn F., 516Fujii, Yoshio, 1183

Gaafar, Hassan A., 1126Galanos, Chris, 250Galelli, Anne, 1081Gamon, Lindsay B., 1168Garaci, E., 1Gardner, Jared J., 824Gfell, M. A., 446Ghadirian, E., 1017Ghose, A. C., 702Ghose, Sandhya, 702Gibbons, R. J., 1006Gilligan, Peter H., 683Ginsburg, H., 133Glass, Roger, 152Gleason, R. Roger, 965Glezen, W. Paul, 453Gmur, Rudolf, 459

i

ii AUTHOR INDEX

Goebel, Werner, 57Goldberg, S., 224Golde, David W., 876Gordon, Ronald E., 414Granoff, Dan M., 257Gray, Gary R., 76Gray, John G., 350Green, Bruce A., 924Green, Theodore J., 15Griffis, Cynthia, 453Grimwood, Brian, 1126Groman, Neal, 48Guenounou, Moncef, 1049Guesdon, Jean-Luc, 496Guggenheim, Bernhard, 459Gulig, Paul A., 516Gusberti, F., 659Gwaltney, Jack M., Jr., 1195Gyles, C. L., 264

Haahr, S., 740Habig, William H., 942Hacker, Jorg, 57Haidaris, Constantine G., 385Haldar, J. P., 702Hall, C. E., 1159Hamada, Shigeyuki, 696Hamilton, I. R., 19Hammarstrom, Lennart, 237Hampar, Berge, 1067Hancock, Gerald E., 848Hancock, R. E. W., 88Hancock, Robert E. W., 170,

1027, 1092Hansen, Eric J., 516Hansen, Gert A., 308Hanson, Barbara A., 341Hardegree, M. Carolyn, 942Harper, James, 424Harrison, Jeffery L., 374Hashimoto, Gotaro, 214Hauser, P., 599Hayden, Frederick G., 1195Haynes, J. David, 385Hendley, J. Owen, 692Herzberg, Mark C., 394Hewlett, Erik L., 33, 692Heyneker, Herbert, 269Higashi, Gene I., 1116Higgins, T., 659Higgs, Gerald A., 71Hodges, Robert S., 113Hof, Herbert, 57Hofmann, Theo, 755H0iby, N., 88H0iby, Neils, 197Holdeman, L. V., 510Holmes, Randall K., 914, 924Honda, Takeshi, 778Hook, Magnus, 628Hopkins, Janet A., 276Horswood, Robert L., 81Houghten, Richard A., 838Hughes, Colin, 57Hull, Richard, 178

Huppert, Milton, 374Huq, Imadul, 152Hurlbert, Ronald E., 1092

Iaconis, Joseph P., 480Inoue, Masakazu, 696Isibasi, Armando, 949Iwasaka, T., 955

Jacobson, R. H., 1159Jennings, Harold, 936Jerrells, Thomas R., 549Jimenez, Enedina, 949Joiner, Keith A., 594Jones, Joye F., 848Jordan, George W., 605Judes, Herbert, 831

Kahane, I., 133Kai, Chieko, 721Kamen, Paul R., 1191Kamerling, J. P., 842Kamiyama, Tsuneo, 789Kapikian, Albert Z., 835Kaplan, Sheldon L., 612Kapperud, Georg, 163Karzon, David T., 214Kaster, Allan G., 716Kemp, C. W., 431Kendal, Alan P., 453Kenimer, James G., 942Kenney, Howard M., 876Keren, David F., 202Kihlstrom, Erik, 930Kilian, Mogens, 126Klein, Thomas W., 421Klevjer-Anderson, Paula, 845Klipstein, Frederick A., 838Klotz, Stephen A., 374Koenig, Daniel, 81Koff, Wayne C., 1067Koga, Toshihiko, 696Kongshavn, P. A. L., 1017Koprowski, Hilary, 301Kroll, Hein-Peter, 1055Kronvall, Goran, 326Krueger, David A., 1152Kubala, Gary J., 427Kulakowska, Malgorzata, 1086Kumate, Jesus, 949Kunkel, Steven L., 1116Kuramitsu, Howard K., 763

Labrousse, Hubert, 496Lam, J. S., 88Lam, K., 88Larrimore, Sylvia, 558Lassen, J0rgen, 163Lee, C. H., 264Lee, Lucy F., 747LeFrock, Jack L., 42Lehrer, Robert I., 10

Lemon, Stanley M., 418Leon, Ofra, 1144Levine, R. P., 907Linde, G. Annika, 237Lipscomb, Mary F., 965Ljungh, Asa, 628Loesche, W. J., 659Logan, Susan M., 675London, William T., 424Lugowski, Czeslaw, 1086Lukehart, Sheila A., 634Lyons, Clifford R., 965

Maas, Werner K., 269MacLaren, David M., 245Maliszewski, Charles R., 208Mandell, Gerald L., 1195Mason, Edward O., Jr., 612Masterson, Robert, 973Mattingly, Stephen J., 141Mayden, Jan, 907Mazaitis, Anthony J., 269McArthur, Hamish A. I., 574McBride, Barry C., 1073McCuskey, Patricia A., 362McCuskey, Robert S., 362McDonald, Roderick A., 202McGarrity, Gerard J., 1168McGuire, R. L., 106McGuire, Travis C., 845McLaughlin, C. A., 1159Meerovitch, E., 1017Megraud, Francis, 1168Melancon, Johanne, 471Mellors, Alan, 64Meltzer, Monte S., 385Meredith, M. P., 1159Mestecky, Jiri, 1041Mettraux, G., 659Mezzatesta, Joseph R., 99Michalek, Suzanne M., 558Miller, James N., 435Miller, Nanette T., 424Miwatani, Toshio, 778Mizuno, Fumiko, 231Mizuno, Junn, 696Mogensen, S. C., 740Moldawer, Lyle L., 997Moon, H. W., 264Moore, W. E. C., 510Mor, Natan, 802Moreno, E. C., 1006Morris, E. Jane, 1073Morris, R. E., 812Moseley, S. L., 264Moxon, E. Richard, 708Munson, Robert S., Jr., 257Murchison, Hettie, 558Murgita, Robert A., 471Murphy, Brian R., 424Murphy, J. R., 224Muscoplat, C. C., 653Musher, Daniel M., 579, 585Mutharia, L. M., 88Mutharia, Lucy M., 170, 1027Myers, Gwendolyn A., 33

INFECT. IMMUN.

AUTHOR INDEX iii

Nachamkin, Irving, 980Nagahama, Masahiro, 1183Nath, Indira, 890Nauciel, Charles, 1049Nedelman, Jerry, 692Nelson, Robert D., 76Newland, John W., 924Niederhuber, John E., 882Norgard, Michael V., 435Nugent, Kenneth M., 1102

Ockenhouse, Christian F., 733O'Connor, Gerald, 1126Offit, Paul A., 293Ohta, Hiroaki, 721Okahashi, Nobuo, 6%Okuda, Toshiro, 618Olsnes, Sjur, 771Onderdonk, A. B., 783Openshaw, Harry, 409Ord6fiez, Nelson, 368Osada, Yasuaki, 618Osterhaus, Ab D., 187Otulakowski, Gail L., 64

Palcanis, K. G., 853Panem, Sandra, 368Panos, Charles, 1144Paranchych, William, 113Pateraki, Evangelia, 4%Pedersen, E. Brandt, 740Persson, Mats A. A., 237Pesanti, Edward L., 1102Picken, Roger N., 269Pier, Gerald B., 170, 936Pierce, Jennie K., 900Plant, Janet E., 71Plotkin, Stanley A., 293Pluschke, Gerd, 907Portocala, Radu, 4%Poulsen, Finn M., 308Prato, Catherine, 863Prince, Gregory A., 81Puccetti, P., 1

Rabin, Myron, 48Rabinovich, Sergio, 818Ranney, R. R., 510Ranney, Richard R., 487Rapp, F., 402Raybould, T. J. G., 653Reilly, M. F., 645Reitano, Maria, 414Rest, Richard F., 99, 1034Rey, Michael, 269Ribi, Edgar, 219Roberts, John F., 350Robertson, Donald C., 539, 683Robrish, S. A., 431Rockhill, Robert, 152Rodolakis, Annie, 525Rodrick, G. E., 1187Rodriguez, Sergio D., 15

Roelants, P., 599Rogers, James E., 1176Rogolsky, Marvin, 973Rolfe, Rial D., 480Romanowska, Elzbieta, 1086Rosenberg, Mel, 831Rosenthal, R. S., 446Rubin, Donald H., 301Rubin, Kristofer, 628Russell, Michael W., 1041Russell, S. Melanie, 531Ryden, Cecilia, 628

Sadowski, P. L., 653Saelinger, C. B., 812Safary, A., 599Saha, K. C., 702Sakuma, Takashi, 567Sakurai, Jun, 1183Salit, Irving E., 755Sastry, Parimi A., 113Sathish, M., 890Saunders, David W., 427Schaffner, Andreas, 1109Schell, Ronald F., 42Schook, Lawrence B., 882Schouls, Leo M., 187Schroer, Kenneth, 1041Sciortino, Carmen V., 990Scott, Patricia J., 202Selsted, Michael E., 10Seniff, Donna A., 1067Sereno, Mitzi M., 835Seriwatana, Jitvimol, 152Sharma, A. K., 890Sharma, Jagdev M., 747Shear, Hannah L., 733Shenep, Jerry L., 257Sheridan, J. F., 955Sherman, D. M., 653Shewen, Patricia E., 64Shiota, Tetsuo, 558Showalter, Stephen D., 1067Shu, Mei-Di, 818Shuster, Charles W., 208Simmons, Donald G., 350Singh, Nalini, 835Sippel, John E., 863Six, Howard R., 453Sly, D. Lewis, 424Smibert, R. M., 510Smith, C. I. Edvard, 237Smith, D. J., 156Smith, Daniel J., 668Snippe, H., 842Snyder, Irvin S., 318So, M., 264Sobrado, Javier, 997Soderlund, Gustaf, 930Specter, S., 1187Speert, David P., 170Spira, W. M., 501Springer, J. A., 653Stanbridge, Eric J., 1136Stein-Streilein, Joan, %5Stewart, Shannon D., 1176

Stroll, Barbara J., 152Sturtevant, Joy E., 869Suenaga, Tohru, 567Sugasawara, Renee J., 863, 980Suly, E. C., 853Sundqvist, Vivi-Anne, 237Suzuki, Keiko, 356Sweet, Richard L., 980Swim, S. C., 446Switalski, Lech M., 628Syed, S., 659Szklarek, Dorothy, 10

Takahashi, Nobuyoshi, 231Takamori, Kenshiro, 231Takeda, Yoshifumi, 778Tamplin, M. L., 1187Tatsumi, Masashi, 789Taubman, M. A., 156Taubman, Martin A., 668Taylor, Peter W., 1055Tenser, R. B., 402Tew, John G., 487Tewari, Ram P., 818Thomsen, Birgitte, 126Thornburg, Robert W., 623Tomlinson, Karen, 1144Tosi, R., 122Trust, Trevor J., 675Tuomanen, Elaine I., 692Turco, Jenifer, 27Twiddy, Edda M., 914

Udoh, A. Ekpe, 64Urbaschek, Bernhard, 362Urbaschek, Renate, 362

Vacheron, Franqoise, 1049Vaidya, Akhil B., 427van Dam, J. E. G., 842van der Donk, Huib J., 187van der Heide, Han G., 187van Eijk, Ron V., 187van Embden, Jan D., 187van Houte, A. J., 842van Olderen, Max F., 187Vasil, Michael L., 276Vavougios, Joanne, 755Verstreate, D. R., 1159Vilcek, Jan, 368Vliegenthart, J. F. G., 842Vodopija, I., 599Von Behren, Larry A., 818Von David, William, 973Vorbrodt, Andrzej, 301

Waalwijk, Cees, 245Wadstrom, Torkel, 628Wagner, Barbara, 326Wagner, Manfred, 326Wahren, Britta, 237Walker, Richard I., 986, 1176Walls, Harriet H., 824

VOL. 42, 1983

iv AUTHOR INDEX INFECT. IMMUN.

Wang, Wen-Lan L., 276Ward, Peter A., 1116Warfield, Donna T., 824Watts, Tania H., 113Webster, Robert G., 424, 453Weinberg, J. Brice, 219Weisbart, Richard H., 876Weiss, Alison A., 33Weiss, Ervin, 831Welch, Rodney A., 178Wellhausen, Samuel R., 882West, Timothy E., 1020Wheat, Robert W., 219Whipp, S. C., 264White, K. L., Jr., 645

Wiatrak, Mitchell, 202Wiedermann, Bernhard L., 612Wilde, C. E., III, 446Wilder, Ronald L., 796Wiley, Bill B., 973Wilkie, Bruce N., 64Willers, J. M. N., 842Williams, Jim C., 887Winkelstein, Jerry A., 708Winkler, Herbert H., 27Winter, A. J., 1159Wondrack, Lillian, 763Wright, Clifford D., 76Wright, Peter F., 214Wyler, David J., 356

Yamamoto, Koichiro, 778Yamamoto, Toshiko, 696Yamanouchi, Kazuya, 721Yeakel-Houlihan, Darlene, 965Yeung, Maria K., 141Yoh, Myonsun, 778Yoshida, Itsuro, 567Yoshikawa, Yasuhiro, 721

Zeiger, Allen R., 1013Zen-Yoji, Hiroshi, 618Ziegler, Donald W., 824Zwahlen, Andre, 708

SUBJECT INDEX

VOLUME 42

Abscessespolymicrobial, 986

O-Acetylationgonococcal peptidoglycan

high-performance liquid chromatography, 446N'-(N-Acetylmuramyl-L-alanyl-D-isoglutamine-N -

stearoyl-L-lysinecomplement, 618

Actinobacillus actinomycetemcomitanskeratinocyte, 1191

Actinomyces viscosuscarbohydrate

continuous culture, 19Adherence

Bordetella sp.ciliated respiratory epithelial cells, 692

H. influenzae, 612L. pneumophila

Fischerella species, 318S. mutans, 558

Alcaligenes faecalisturkeysupper respiratory tract, 350

Alternative complement pathwayfowlpox virus, 721

Amoebiasismacrophages, 1017

Antiactin antibodiesL. donovani, 496

Antigen-presenting cellsinfluenza, 965

Antipneumococcal antibodiesC3b

classical complement pathway, 594Antitubulin antibodies

L. donovani, 496A/Seal/Mass/1/80 virus

squirrel monkeys, 424Aspergillus spores

macrophage, 1109Autoagglutination

Y. enterocoliticahemagglutinin, 163

Babesia boviscloning, 15

BacteremiaH. influenzae

noncapsular antibody, 257Bacteriocin R1

S. aureusplasmid, 973

Bacteroides intermediusmonoclonal antibodies, 459

Bacteroides vulgatuscolitis, 783

Bifidobacteriumdextranase, 716

B lymphocytesS. aureus

peptidoglycan, 1013Bordetella pertussis

fimbriaesubstructure, 308

Tn5-induced mutations, 33Bordetella sp.

adherenceciliated respiratory epithelial cells, 692

Brucella abortusporinmuramyl dipeptide, 1159protein, 1159trehalose dimycolate, 1159

Bursal diseaselymphoid cells, 747natural killer cells, 747

Campylobacter jejunienteritis, 1176outer membrane proteins, 276protein antigens, 675

Candida albicanscyclophosphamide, Imyeloperoxidasemannan, 76

S. aureus, 285Candida spp.

vascular endotheliumadherence, 374penetration, 374

Caprine arthritis-encephalitis virusvariants, 845

CarbohydrateA. viscosus

continuous culture, 19S. sanguis, 696

CarbohydratesC. trachomatisMcCoy cells, 930

Cardiovascular systemC. perfringens

epsilon toxin, 1183Cationic protein

peptidesmacrophages, 10

C3bclassical complement pathway

antipneumococcal antibodies, 594Cell walls

streptococcus group A, 796Chlamydia psittacilymphokine

interferon gamma, 1152Chlamydia psittaci var. ovis

temperature-sensitive mutants, 525Chlamydia trachomatisMcCoy cells

carbohydrates, 930lectins, 930

Cholera enterotoxin

v

vi SUBJECT INDEX

monoclonal antibodies, 914Cholera toxin

E. coliheat-labile enterotoxin, 683

V. choleraegenes, 427

Classical complement pathwayC3bantipneumococcal antibodies, 594

CloningB. bovis, 15

Clostridium difficileintestines, 480

Clostridium perfringensepsilon toxin

cardiovascular system, 1183Colitis

B. vulgatus, 783ComplementH. influenzae, 708Vibrio species, 1187

Connective tissue diseaseneutrophilslymphokine, 876

Corynebacterium diphtheriaetox geneDNA, 48

Coxiella burnetliQ fever, 887

Crevicular fluidS. sanguis

neuraminidase, 1073Crossed immunoelectrophoresis

P. aeruginosaouter membrane, 88

Cross-neutralizationhepatitis A virus, 418

CyclophosphamideC. albicans, I

Cystic fibrosisP. aeruginosa, 197

lipopolysaccharide, 170Cytomegalovirusimmunoglobulin A, 237immunoglobulin G, 237

Dental plaquehydrophobicity, 831Stickland reaction, 431

DextranaseBifidobacterium, 716

Diabetes mellitusencephalomyocarditis

interferon, 605Diarrhea

E. coligene probes, 152

Diphtheria toxinendocytosis, 812

DNAC. diphtheriae

tox gene, 48T. pallidumE. coli, 187

Ectromelia virusM. bovis BCG, 567

Eikenella corrodensmajor outer membrane protein, 208

Encephalomyocarditis virusdiabetes mellitus

interferon, 605Endocytosis

diphtheria toxin, 812Endotoxin

interleukin 1, 997M. bovis BCG

hepatic circulation, 362Kupifer cells, 362

Enteric colibacillosisE. coli, 653

EnteritisC. jejuni, 1176

Enterobacterial common antigentetanus toxoid, 1086

EnterotoxinE. coli

cholera toxin, 683heat stable

E. coli, 539K. pneumoniae, 838

heat-stable IIE. coli, 264

EnterotoxinsE. coli

lincomycin, 778tetracycline, 778

Enzymesmonocytes

leishmaniasis, 356Epithelial cells

Bordetella sp.adherence, 692

Epsilon toxinC. perfringens

cardiovascular system, 1183Erythrocytes

P. falciparumglycophorin, 133

Escherichia colicapsule, 907diarrheagene probes, 152

enteric colibacillosis, 653enterotoxins

lincomycin, 778tetracycline, 778

heat-labile enterotoxincholera toxin, 683

heat-stable enterotoxin IIgene, 264nucleotide sequence, 269producers, 264

heat-stable enterotoxins, 539hemolysin, 178

urinary tract infection, 57mannose-resistant fimbriae

genes, 900nephropathogenicity

hemolysin, 245O antigen, 907pili, 755

INFECT. IMMUN.

SUBJECT INDEX vii

serummembrane, 1055

T. pallidum, 435DNA, 187

type 1 fimbriaeorganelles, 333

ExopolysaccharidesP. aeruginosa

lectin, 574

FibronectinStaphylococcus strains, 628

FimbriaeB. pertussis

substructure, 308E. coli

organelles, 333Fischerella species

L. pneumophilaadherence, 318

Fowlpox virusalternative complement pathway, 721

Gangliosidesinfluenza vaccine

neuritis, 824Gene probes

E. colidiarrhea, 152

Glomerulilipoteichoic acid, 1144S. pyogenes, 1144

GlucosyltransferaseS. sanguis, 156

GlycophorinP. falciparum

erythrocytes, 133Gonococcal peptidoglycan

high-performance liquid chromatographylysozyme, 446O-acetylation, 446

Granulomasmacrophages

hydroxyeicosatetraenoic acids, 1116prostaglandins, 1116superoxide anion, 1116

Haemophilus influenzaeadherence, 612bacteremia

noncapsular antibody, 257complement, 708immunoglobulin Al

protease, 126major outer membrane proteinmonoclonal antibodies, 516

Heart-reactive antibodyhybridomagroup A streptococci, 531

Heat-stable enterotoxinE. coli

nucleotide sequence, 269HeLa cellsN. gonorrhoeae

protein II, 980

HemagglutininY. enterocolitica

autoagglutination, 163Hemagglutinin protease

V. cholerae, 639Hemolysin

E. coli, 178nephropathogenicity, 245urinary tract infection, 57

Hepatectomyherpes simplex virus

thymidine kinase, 402Hepatic circulationM. bovis BCG

endotoxin, 362Hepatitis A virus

cross-neutralization, 418Hepatobiliary transportimmunoglobulin A, 1041

HEp-2 cellsinterferon

S. flexneri, 1198S. paratyphi-B, 1198S. typhimurium, 1198

Herpes simplex virushepatectomy

thymidine kinase, 402interferon, 740motor neurons

hypoglossal model, 409suppressor cells, 955suppressor factors, 955

Herpesvirusbovine type I

Ileukocytes, 106lymphokinehybridoma, 1067

High-performance liquid chromatographygonococcal peptidoglycan

lysozyme, 446O-acetylation, 446

Histoplasmosissilica

poly-2-vinylpyridine-N-oxide, 818HLA

interferon gammaDC locus, 122DR locus, 122

HIN virusHouston, Tex., 453

Houston, Tex.HlNI virus, 453

Human serumVibrio species, 1187

Hybridomaheart-reactive antibodygroup A streptococci, 531

herpesviruslymphokine, 1067

Hydrophobicitydental plaque, 831

Hydroxyeicosatetraenoic acidsgranuloma

macrophages, 1116Hypoglossal model

herpes simplex virusmotor neurons, 409

VOL. 42, 1983

viii SUBJECT INDEX

Ibuprofenendotoxin, 997interleukin 1, 997

Immune complexessyphilis, 579

Immune modulatorsinterferon, 728

Immunoglobulinmonocytes

periodontal bacteria, 853thymectomized rats, 668

Immunoglobulin Acytomegalovirus, 237hepatobiliary transport, 1041S. flexneri, 202

Immunoglobulin AlH. influenzae

protease, 126Immunoglobulin G

cytomegalovirus, 237S. aureus

teichoic acid, 1020Influenzapulmonary antigen-presenting cells, 965trachea, 1102

Influenza vaccineneuritis

gangliosides, 824Influenza viruslymphocytes

antibody-dependent cellular cytotoxicity, 214Interferon

encephalomyocarditis virusdiabetes mellitus, 605

HEp-2 cellsS. flexneri, 1198S. paratyphi-B, 1198S. typhimurium, 1198

herpes simplex virus, 740immune modulators, 728rickettsiaelymphokine, 27

Interferon-asystemic lupus erythematosus

kidneys, 368Interferon-a2polymorphonuclear neutrophils, 1195

Interferon--yC. psittacilymphokine, 1152

HLADC locus, 122DR locus, 122

Interleukin Iibuprofen, 997peptidoglycans, 1049

IntestinesC. difficile, 480

I regionmacrophages

R. tsutsugamushi, 549Iron

V. choleraeouter membrane proteins, 990

KeratinocyteA. actinomycetemcomitans, 1191

Kidneysinterferon-a

systemic lupus erythematosus, 368Klebsiella pneumoniae

heat-stable enterotoxin, 838Kupffer cellsM. bovis BCG

endotoxin, 362

LectinP. aeruginosa

exopolysaccharides, 574Lectins

C. trachomatisMcCoy cells, 930

Legionella pneumophilaFischerella species

adherence, 318macrophages, 421

Leishmania donovaniantiactin antibodies, 496antitubulin antibodies, 496

LeishmaniasisKala azar, 702parasite-monocyte interactionsenzymes, 356

post-Kala azar, 702Lens

S. mirum, 1168Leprosy

suppressor factormonocytes, 890

Leukocytesbovine herpesvirus type 1, 106

LevanaseS. salivarius, 231

LincomycinE. coli

enterotoxins, 778V. mimicus

toxin, 501LipopolysaccharideN. meningitidismonoclonal antibodies, 863

P. aeruginosacystic fibrosis, 170

Y. pestis, 1092Lipopolysaccharides

gram-negative bacteria, 250Lipoteichoic acid

S. pyogenes, 1144Lymphoblastoid cellsM. hyorhinis, 1136

Lymphocytesinfluenza

antibody-dependent cellular cytotoxicity, 214N. meningitidis, 471

Lymphoid cellsbursal disease, 747

LymphokineC. psittaci

interferon-y, 1152herpesvirushybridoma, 1067

neutrophilsconnective tissue disease, 876

INFECT. IMMUN.

SUBJECT INDEX ix

rickettsiaeinterferon, 27

Lymphokinesmacrophages

phagocytosis, 733Lysis

T. lewisipolypeptides, 869

Lysozymegonococcal peptidoglycan

high-performance liquid chromatography, 446

Macrophagesamoebiasis, 1017Aspergillus spores, 1109cationic proteins

peptides, 10granuloma

hydroxyeicosatetraenoic acids, 1116prostaglandins, 1116superoxide anion, 1116

I regionR. tsutsugamushi, 549

L. pneumophila, 421lymphokines

phagocytosis, 733M. Ieprae

rifampin, 802porins

tumors, 219S. mansoni, 882

Major outer membrane proteinE. corrodens, 208H. influenzae

monoclonal antibodies, 516Mannanmyeloperoxidase

C. albicans, 76Mannose-resistant fimbriae

E. coligenes, 900

McCoy cellsC. trachomatis

carbohydrates, 930lectins, 930

Meningococcal vaccinesgroup C polysaccharide, 599

02-Microglobulinbeta-hemolytic streptococci, 326

Mitogensperiodontitis, 487

Monoclonal antibodiesmonoclonal antibodies

B. intermedius, 459cholera enterotoxin, 914H. influenzae

major outer membrane protein, 516N. meningitidis

lipopolysaccharide, 863P. aeruginosa

porin protein F, 1027rotavirus, 835tetanus toxin, 942

Monocytesimmunoglobulin

periodontal bacteria, 853

leishmaniasisenzymes, 356

leprosysuppressor factor, 890

N. gonorrhoeaephagocytes, 99

Motor neuronsherpes simplex virus

hypoglossal model, 409Muramyl dipeptide

B. abortusporin, 1159

Muramyl peptidesmyelopoiesis, 1081

Mycobacterium bovis BCGectromelia virus, 567endotoxin

hepatic circulation, 362Kupffer cells, 362

Mycobacterium lepraemacrophages

rifampin, 802Mycoplasma hyorhinis

lymphoblastoid cells, 1136Myeloperoxidase

C. albicansmannan, 76

Myelopoiesismuramyl peptides, 1081

Naegleria fowlerihost resistance, 645

Natural killer cellsbursal disease, 747thymocytes

T. gondii, 789Neisseria gonorrhoeaeHeLa cells

protein II, 980outer membrane proteins

phagolysosomes, 1034phagocytes

monocytes, 99Neisseria meningitidis

lipopolysaccharidemonoclonal antibodies, 863

lymphocytes, 471Nephropathogenicity

E. colihemolysin, 245

NeuraminidaseS. sanguis, 1006

crevicular fluid, 1073serum, 1073

Neuritisinfluenza vaccine

gangliosides, 824Neutrophilslymphokine

connective tissue disease, 876Nucleotide sequence

E. coliheat-stable enterotoxin II, 269

OrganellesE. coli

VOL. 42, 1983

x SUBJECT INDEX

type 1 fimbrae, 333Outer membrane proteins

C. jejuni, 276N. gonorrhoeaephagolysosomes, 1034

V. choleraeiron, 990

Oxygen tensionperiodontal pockets, 659

Pasteurella haemolyticasialoglycoprotein, 64

Peptidescationic proteinsmacrophages, 10

PeptidoglycanS. aureusB lymphocytes, 1013

Peptidoglycansinterleukin 1, 1049

Periodontal bacteriaimmunoglobulin

monocytes, 853Periodontal pocketsoxygen tension, 659

Periodontitisadult humans, 510mitogens, 487

PhagocytesN. gonorrhoeae

monocytes, 99Phagocytosismacrophages

lymphokines, 733PhagolysosomesN. gonorrhoeae

outer membrane proteins, 1034Pili

E. coli, 755Plaque reduction neutralization

rotavirus, 293Plasmid

S. aureusbacteriocin RI, 973toxin B, 973

Plasmodium falciparumerythrocytes

glycophorin, 133tumor necrosis factor, 385

PlateletsS. sanguis, 394

Polar piliP. aeruginosa, 113

Polymorphonuclear neutrophilsinterferon-a2, 1195

PolypeptidesT. lewisi

lysis, 869Polysaccharide

P. aeruginosa, 936S. typhi, 949

Polysaccharide group Cmeningococcal vaccines, 599

Poly-2-vinylpyridine-N-oxidesilica

histoplasmosis, 818

PorinB. abortusmuramyl dipeptide, 1159protein, 1159trehalose dimycolate, 1159

macrophagestumors, 219

Y. pestis, 1092Porin protein F

P. aeruginosamonoclonal antibodies, 1027

Prostaglandinsgranulomamacrophages, 1116

ProteaseH. influenzaeimmunoglobulin Al, 126

ProteinB. abortus

porin, 1159T. pallidum, 623T. pertenue, 623

Protein antigensC. jejuni, 675

Protein IIN. gonorrhoeaeHeLa cells, 980

Pseudomonas aeruginosacystic fibrosis, 197

lipopolysaccharide, 170exopolysaccharides

lectin, 574outer membrane

crossed immunoelectrophoresis, 88polar pili, 113polysaccharide, 936porin protein Fmonoclonal antibodies, 1027

Pyridoxalstreptococci, 414

Q feverC. burnetii, 887

Radioimmunoassayrotavirus, 293

Radioimmunoprecipitationrotavirus, 293

Reovirusmouse embryos, 301

Rickettsiaeinterferon

lymphokine, 27Rickettsia tsutsugamushiimmune serum

infectivity, 341macrophages

I region, 549RifampinM. leprae

macrophages, 802Rotavirusmonoclonal antibodies, 835plaque reduction neutralization, 293radioimmunoassay, 293radioimmunoprecipitation, 293

INFECT. IMMUN.

SUBJECT INDEX xi

Salmonella paratyphi-BinterferonHEp-2 cells, 1198

Salmonella typhipolysaccharide, 949

Salmonella typhimuriumchronic infection, 71interferonHEp-2 cells, 1198

Schistosoma mansonimacrophages, 882

SerumE. colimembrane, 1055

S. sanguisneuraminidase, 1073

Shigella flexneriimmunoglobulin A, 202interferonHEp-2 cells, 1198

SialoglycoproteinP. haemolytica, 64

Silicahistoplasmosis

poly-2-vinylpyridine-N-oxide, 818Spiroplasma mirum

rabbit lens, 1168Staphylococcus aureus

C. albicans, 285peptidoglycanB lymphocytes, 1013

plasmidbacteriocin Rl, 973toxin B, 973

teichoic acidimmunoglobulin G, 1020

Staphylococcus strainsfibronectin, 628

Stickland reactiondental plaque, 431

Streptococcibeta-hemolytic

02-microglobulin, 326pyridoxal, 414type III group B

mutants, 141Streptococcus group A

cell walls, 7%heart-reactive antibody

hybridoma, 531Streptococcus mutansadherence defect, 558

Streptococcus pneumoniaevaccine, 842

Streptococcus pyogenesglomeruli, 1144

Streptococcus salivariuslevanase, 231

Streptococcus sanguiscarbohydrate, 6%glucosyltransferase, 156neuraminidase, 1006

crevicular fluid, 1073serum, 1073

platelet aggregation, 394Superoxide aniongranuloma

macrophages, 1116Suppressor cells

herpes simplex virus, 955Suppressor factor

herpes simplex virus, 955leprosy

monocytes, 890Syncytial virus

respiratorycotton rats, 81

Syphilisimmune complexes, 579treponemal antigens, 585

Systemic lupus erythematosusinterferon-oa

kidneys, 368

Teichoic acidS. aureusimmunoglobulin G, 1020

Tetanus toxinmonoclonal antibodies, 942

Tetanus toxoidenterobacterial common antigen, 1086

TetracyclineE. coli

enterotoxins, 778Thymidine kinase

herpes simplex virushepatectomy, 402

Thymocytesnatural killer cells

T. gondii, 789TnS

B. pertussis, 33tox gene

C. diphtheriaeDNA, 48

ToxinV. mimicuslincomycin resistance, 501

Toxin BS. aureus

plasmid, 973Toxofactor

T. gondii, 1126Toxoplasma gondiithymocytes

natural killer cells, 789toxofactor, 1126

Tracheainfluenza, 1102

Trehalose dimycolateB. abortus

porin, 1159Treponemal antigens

syphilis, 585Treponema pallidumDNA

E. coli, 187E. coli, 435immune serum, 42proteins, 623T. pertenue, 634

Treponema pertenueproteins, 623

VOL. 42, 1983

xii SUBJECT INDEX

T. pallidum, 634Trypanosoma lewisi

lysispolypeptides, 869

Trypanosomiasisimmunodeficiency, 848

Tumor necrosis factorP. falciparum, 385

Tumorsporinsmacrophages, 219

TurkeysA. faecalis

upper respiratory tract, 350

Upper respiratory tractturkeysA. faecalis, 350

Urinary tract infectionE. coli

hemolysin, 57

Vascular endotheliumCandida spp.

adherence, 374penetration, 374

Vibrio choleraecholera toxin genes, 427El Tor biotype

genes, 924hemagglutinin protease, 639iron

outer membrane proteins, 990vibriophage VcA-3, 224

Vibrio mimicustoxin

lincomycin resistance, 501Vibriophage VcA-3

V. cholerae, 224Vibrio speciescomplement, 1187human serum, 1187

Yersinia enterocoliticaautoagglutination

hemagglutinin, 163Yersinia pestislipopolysaccharide, 1092porin, 1092

INFECT. IMMUN.

INDEX TO DATE OF ISSUE

Date of Issue

30 September 198331 October 198329 November 1983

STATEMENT OF OWNERSHIP MANAGEMENT AND CIRCULATIONAeqs;ire by s9 U.S.c 36853A TITLE OF PUBLICATION 18. PUBLICATION NO. 2. DATE OF FILING

Infection and Ilumunity 30 September 19833, FREOUENCY OF ISSUE 3A. NO. OF ISSUES PUBLISHED 38. ANNUAL SUBSCRIPTION

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Anerican Society for Microbiology, 1913 I Street, N.W., Washington, D.C. 20006EOITOR (N.-e d CorIe. M,ainr Add-r

Director of PublicationsWalter G. Peter III, 1913 I Street, N.W., Washington, D.C. 20006

MANAGING EDITOR INe..d Co,el.,aM.AgsAddr-)Walter G. Peter III, same as above

Ifeo,;ipOeGhd by. .o-pSWol it.-tIo,I.nd dd .-Itb-mDdt d It tmr nbE,Ae,pi d

American Society for Microbiology 11913 I Street, N.W., Washington, D.C. 20006

S KNOWN BONDHOLDERS. RTGAGEES.ANDOTHER SECURITY HOLDERS OWNING OR HOLOINGS PERCENT OR MORE OF TOTALAMOUNT OF BONDS. MORTGAGES OR OTHER SECURITIES (ifA.seHee,t-tHH

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9 FORCOMPLETION BY ONPROFITORGANIZATIONS AUTHORIZEO TO MAIL AT SPECIAL RATES ISecoe O23 12DMMoylyTh. p.,p.%., f-untion. ewlndorfit allw of tht. wpiutio.aned th. xmP tat.. for FoeAr.l ri.-- t.. P.,pr-te ICh,, ...af

Xi HAS NOT CHANGEDDURING _ HAS CHANGED DURING (ItO.eaad pubS -SSHbH t-p-eo ti ofPRECEDING12MONTHS U PRECEDING12MONTHS wh

10S AVERAGE NO. COPIES EACH ACTUAL NO. COPIES OF SINGLEEXTENT AND NATURE OF CIRCULATION ISSUE DURING PRECEDING ISSUE PUBLISHED NEAREST TO

12 MONTHS FILING DATE

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1.Se hog ze n mses tet deedrube e 4963 5529

2 M.al Sobso.HS,H (Nonmember) 1550 1801

C TOTAL PAID CIRCULATION (S..p,1eosIdIUoB2 6513 7330

D. FREE DISTRIBUTION BY MAIL. CARRIER OR OTHER MEANSSAMPLES, COMPLIMENTARY. AND OTHER FREE COPIES 100 100

E TOTAL DISTRIBUTION 1S0.a ofC..d D1 6613 7430F, COPIES NOT DISTRIBUTED

I. Oo.I oer unerSod,OR,SO*S* eSoSOB 2140 1348

2~R.,--- from, Ne- Ag.nvt.

G TOTAL (S.ofE. rF d 2--IdeH,W aIet.enSs.,ep- .-i .A) 08753 877811 N SIGNATU17 AND TITLE OF EDITOR. PUBLISHER, BUSINESS MANAGER, OR OWNER

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OctoberNovemberDecember

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PURITY * TOXICITY * SOLUBILITYThese properties of endotoxins can have dramatic effects on immunological experiments. Our RefinedStandard Endotoxins are tested to strict tolerances to establish optimal toxicity and solubility as well ashighest purity, so you can be confident of your results.

Choose from our growing list of quality Refined Standard Endotoxins.

O S. typhimurlum Re-mutant O E. col 0113 O Serratia marcescensO S. typhimurium wild-type 0 E. coliOI0111:34 0 Shigella flexnen0 S. typhi 0901 0 E. coli 055:85 0 Pseudomonas aeruginosa0 S. minnesota R595 0 E. coliO128:8120J S. minnesota wild-type 0 E. coli I1 l:00K235 Available in 5mg0 S. abortus equi 0 E. coli 026:B6 and 25mg units0 S. entenltidis 0 E. coli 01 27:B8

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