I N D E X

Abueloo J. G., 113 Acetylethyleneimine, inactivation and antigenic-

i ty of foot-and-mouth disease virus by, 1100 Aeriflavine, immunosuppressant effects of, 314 m, immunosuppression by, 1013 Actinomycin, inhibition of antibody production

and acquired immunologic tolerance by, 718 Ada, G. L., 665 Adams, Raymond R., Jr. , 895 Adenovirus and papovavirus, interrelationship,

422 M-antibody agglutination reactions, 810 Adler, Frank J., 26, 39 Agar interaction in immunodiffusion, 156 Agglutination, erythrocyte, inhibitory action of

EDTA on, by lectins, 876 M reactions, 810 Agglutinator factor, rabbit , 273 Atbright, J. F. , 368 Albumin characteristic of bovine cerebrospinal

fluid, 629 Alkylation, effect on -~A isoagglutination, 771 Allansmith, Mathea, 951 Allelie allotype distribution, 404 Allen, Peter Z., 918 Allergen binding by immunoglobulins, 937 Allotypes, allelic, distribution among ~G-im-

munoglobulins and purified anti-hapten anti- bodies, 404

Alveolar macrophages, effect of bacillus Calmette- Gudrin in, 125

Amantadine, antiviral act ivi ty of, 1090 Analysis, double diffusion, in agar of hapten spe-

cific immune systems, 1067, 1074 Anaphylatoxin formation by purified human C'I

esterase, 1080 Anaphylaxis, circulatory collapse in, 1 m, passive uveal, 651 - - , systemic, effect of hypothermia on, 621

, , produced by soluble bovine serum albumin- antibody complexes, 1153

Anderson, W. French, 804 Anti-antibody, 273 Anti-p-azobenzoate antibodies, purified antibody

fractions obtained from, 991 Anti-benzoate antibodies, heterogeneity of, 455 Antibody-adenovirus, agglutination reactions, 810 - - a f f i n i t y and biologic activity, 436 ~ , anti-p-azobenzoate, heterogeneity of, 991 - - , anti-benzoate, heterogeneity of, 455 - - , anti-dinitrophenyl, relationship between

affinity and biologic activities, 765 - - , anti-kidney, digestion of, 282

M, anti - protein, radioimmunoelectrophoretic s tudy of, during primary response, 981

- - , effect of variation in antibody~hapten asso- ciation constant upon the biologic activi ty of, 436

- - , equine, to human 7~-globulin, 918 - - , fluorescein-isothiocyanate-labeled, 225 ---forming cells in blood, 109

fractionation, micromethod of, 446 - - , ~G- and ~.M-globulin, comparisons of ~A

isohemagglutinin with, 197 - - -hapten association constant, effect of varia-

tion in, upon the biologic activity of the anti- body, 436

- - , heteroclitic, origin in immune sera, 378 M, heterogeneity of combining sites of, 991

as determined by specific immunoadsorbents, 446, 455

- - , local cellular, 209 - - , mercaptoethanol-sensitive 7 S, in mouse

antisera to protein antigens, 39 - - , mouse, 26, 39 - - , - - , response to sheep red cells, 26 - - , multiple, in single plasma cells, 214 - - , precipitating, distribution among human sera,

181 - - production in germ-free mice and guinea pigs,

3OO , inhibition of, by actinomycin, 718

_ _ m, variations, 542 - - , psittacosis virus, in domestic pigeons, 1107 ~ , purified anti-hapten, distribution of allelic

aItotypes among, 404 response, effect of antigen dose on, 466

- - to coxsackieviruses, 54, - - - - to mycobaeterial antigens, 100 - - , restitution of immunoglobulin sequence by,

345 - - , sheep diphtheria and tetanus, heterogeneity

of, 480 - - , skin-sensitizing, part ial separation of, from

antibodies which bind antigens in vitro, 937 - - staining, fluorescent, 225

synthesis, stabili ty of messenger RNA in, 254 synthesized during immune response to Lepto-

spira biflexa, 887 - - , transfer of, from ewes to lambs, 510 ~ , Vibrio fetus, in bovine serum, 1002 Anti-dinitrophenyl antibodies, relationship be-

tween affinity and biologic activities, 765 Antigen, complement-fixing, of Rickettsia orien-

talis, 412 concentration and nonreaching additives, in-

1175

1176 INDEX [VOL. 95

fluences on mobility and diffusion in immuno- electrophoresis, 1142

- - , dinitrophenylated Bacitracin A as, 113 - - dosage, influence of, on kinetics of hemagglu-

t inating antibody production, 368 - - dose, effect on antibody response, 466 - - , Eaton pleuropneumonia-like organism com-

plement-fixing, 19 - - , enterovirus immunizing, in the form of cation-

stabilized and concentrated virus prepara- tions, 9

in immunity, 665 m, mycobacterial, antibody response to, 100

of coxsackievirus, 818 - - , precipitating, viral and soluble, 189 ~ , protein, mercaptoethanol-sensitive 7 S anti-

bodies to, in mouse antisera, 39 - - , ragweed, homogeneity of, 48 - - , red cell, identified by isoantibodies, 148 - - , restitution of immunoglobulin sequence by,

345 ~ , soluble protective of BordeteUa pertussis, 643 ~ , splenic transplantation, destruction of, by

factor present in liver, 673 ~ , synthetic polypeptide, 542 ~ , varicella-zoster, complement fixation studies

with, 692 Antigenic differentiation of polioviruses by ab-

sorbed hyperimmune sera, 171 - - specificity in delayed hypersensitivity, 331 Antigenicity, in schistosome egg antigen in lung

tissue, 959 of synthetic polypeptides, 1095

Anti-kidney antibody, digestion of, 282 Anti-protein antibodies, rabbit , radioimmuno-

electrophoretie study of, during primary response, 981

Antiserum, behavior of vaecinia virus particles with, 737

~ , chicken-precipitating, immunoelectrophoresis of, 418

~ , mouse, mercaptoethanol-sensitive 7 S anti- bodies in, 39

- - , passive protection by, 567 ~ , preparation in large animals, 895 ~ , rhesus monkey, to human ~-globul ins (~M)I

87 Anti-testosterone antibodies, 262 Antiviral act ivi ty of amantadine, 1090

dynamics of 5-iodo-2-deoxyuridine, 635 Appendix, role in hemolysin response, 306 Austen, K. Frank, 621 Austin, Caroline M., 665 Autoantibody, intrinsic factor, identification of,

536 Azadova, N. B., 791

Bacillus Calmette-Gu~rin, effect on levels of acid phosphatase, lysozyme and cathepsin in al- veolar macrophages, 125

Bacitraein A, dinitrophenylated, as an antigen, 113

Bacteria, Gram-negative, bactericidal action of normal serum on, 75

Bactericidal action of normal serum on Gram- negative bacteria, 75

Bailey, Elizabeth Jane, 1100 Bakemeier, Richard F., 880 Barnett , Eugene V., 536 Barth, Werner, 781 Basement membrane, human glomerular, proper-

ties of, 517 Bauer, D. C., 887 Baxter, James H., 282 Beardmore, W. B., 422 Beiser, Sam M., 262 Benacerraf, Baruj, 1067, 1074 Bence-Jones proteins, subtypes of, 295 Benedict, Albert A., 855 Benjamini, E., 162 Bennett, Boyce, 80, 656 Bergman, R. K., 1 Bernier, George M., 246 Beryllium as granuloma-producing agent in

Freund's adjuvant, 846 Bilbo, Richard E., 937 Birch, Suzette M., 70 Bloch, Kurt J., 621 Blood, antibody-forming cells in, 109

groups in the rabbit , 148 BordeteUa pertussis, soluble protective antigen

and histamine-sensitizing factor of, 643 Boreek~, L., 387 Borsos, Tibor, 559 Bovine serum albumin-antibody complexes, sys-

temic anaphylaxis produced in guinea pigs by, 1153

- - - - - , anti-bovine serum albumin specificity and binding affinity after termination of tolerance to, 546

m _ inhibitor of poliovirus, 909 Braye, Edward T., 895 Broderick, Edward J., 643 Bronsky, Edwin A., 718 Brown, Russell W., 895 Buell, Donald, 951

C~I esterase and anaphylatoxin, 1080 Capalbo, Elmo E., 466 Carpentier, D. C., 1057 Catabolism of ~/G subunits and chains, 1034 Cebra, John J., 230, 246 Cells, antibody-forming, conversion of non-

immune spleen cells to, by RNA, 583 , , in blood, 109

1965] INDEX 1177

- - , heterologous, phagoeytosis of mouse tumor cells by, 80

- - , homologous, phagoeytosis of mouse tumor cells by, 80

- - , lymph node, single, producing heteroclitic bacteriophage antibody, 378

- - , lymphoid, in thymectomized rats, 602 - - , oral mucosal, plaque formation by, 209 - - , phagocytic, cellular kinetics of, 1134 - - , red, sheep, response of mouse antibodies to, 26 - - , single plasma, multiple antibodies in, 214 - - , spleen, nonimmune, conversion to antibody-

forming cells by RNA, 583 - - , tissue culture, measles infection in, 840 - - , tumor, mouse, phagocytosis of, 80 Cerebrospinal fluid, bovine, albumin and ~/-glob-

ulin characteristic of, 629 Chains, polypeptide, frequency distribution of,

in human tissue, 246 Chang, P. W., 591 Choppin, Purnell W., 730 Circulatory collapse in anaphylaxis and hista-

mine toxicity, 1 Claman, Henry N., 718 Coccidioides immitis infection, enhancement of

immunity to, 1048 Cohen, Carl, 148, 273 Cohen, Edward P., 583 Cohen, Irun R., 131 Cold protection, limitations of, 621 Cole, Leonard J., 945 Coleman, Monroe K., 156 Coleman, Virginia, 635 Collagen in flea bite hypersensitivity, 162 Collapse, circulatory, in anaphylaxis and hista-

mine toxicity, 1 Complement dependent precipitation, 1067 - - , first component of, activated, hemolysin t i t ra-

tion based on fixation of, 559 - - fixation, quantitative, with pelioviruses, 70 - - - - w i t h varicella-zoster antigens, 692 ---fixing antigen of Rickettsia orientaIis, 412 - - , hemolytic, a new component of, 355 Complexes, immune, formed by cross-reacting

systems, effect of relative solubility of, 1074 Conjugates, globulin, chromatographic purifica-

tion of, 230 Contact sensitizers, immunologic unresponsive-

ness after topical application of, 397 Coxiella burneti, phase variation in, 880 Coxsackievirus, antigens of, 818 Crab, horseshoe, immunochemical studies of, 141 Crosby, Louise K., 583 Crowle, Alfred J., 834

Dalbow, Milton H., Jr., 209 Daniel, Thomas M., 100 Davies, W. L., 1090

Davis, Starkey D., 75 de Buren, F. P., 162 Dennis, Juanita, 54 Deutsch, H. F., 87 Dins da Silva, W., 1080 Diffusion, immune, comparative, at gelatin-agar

interfaces, 704 Dinh, Bao-Linh, 574 Diphtheria, sheep, and tetanus antibodies, heter-

ogeneity of, 480 Draper, Laurence R., 306 Dray, Sheldon, 404, 525, 823 Dreesman, Gordon, 855 Dudman, W. F. , 704 Dufour, Didier, 574 Dukler, R., 171

Eaton pleuropneumonia-like organism comple- ment-fixing antigen, 19

Edsall, Geoffrey, 487 EDTA inhibition oil erythrocyte agglutination by

lectins, 876 Eisen, Herman N., 404,436 Ekstedt, Richard D., 131 Engle, Ralph L., Jr., 295 Enterovirus hemagglutination, inhibition of, 1111

immunizing antigens in the form of cation- stabilized and concentrated virus prepara- tions, 9

- - , preparation of antiserum to, in large animals, 895

Erlanger, Bernard F., 262 Erythrocyte, agglutination, inhibitory action of

EDTA on, by lectins, 876 - - , sensitization by one molecule of hemolysin,

559 Evans, T. W., 368 Eylan, E., 171

Factor, rheumatoid, reactivi ty of, with rabbit ~.-globulin, 614

Fahey, John L., 781 Farr , Richard S., 314, 1013 Feingold, B. F., 162 Fellowes, O. N., 1100 Flagellin, SalmoneUa adelaide, immunologic toler-

ance to, 665 Flanagan, John F., 494 Flax, Martin H., 846 Flea bite hypersensitivity, role of collagen in, 162 Fluerescein isothiocyanate and its protein con:

jugates, chemical and physical variables affecting, 1165

---labeled w-globulin, properties of, 442 Fluorescent antibody staining, 225 Fogel, A., 171 Foot-and-mouth disease virus inactivation of,

1100

1178 INDEX [voL. 95

Fractionation of determined cell populations, 288 Freeman, M. J., 981 Friedman, Robert M., 696 Frommhagen, Laurence H., 442, 818 Fudenberg, H. Hugh, 197, 501

Galasso, G. J., 737 Gehle, Warren, 810 Gerber, Paul, 70 Gilden, Raymond V., 909 Gill, Thomas J., I I I , 542, 794, 804 Globulin conjugates, chromatographic purifica-

tion of, 230 v-Globulin, characteristic of bovine cerebrospinal

fluid, 629 , chicken, papain-digested, 855

- - - - - , cross-reactions among, 118 - - - - , fiuoreseein-labeled, properties of, 442 - - - - - polypeptide chains, use of tetramethylrho-

daminc-immune globulin conjugates in cellu- lar localization of, 230

- - - - , rabbit , reactivi ty of rheumatoid factor with, 614

- - - - - , subunits and chains, catabolism of, 1034 ~.2-Globulin, human, equine antibodies to, 918 -yM-Globulin (~)~, human, rhesus monkey anti-

sera to, 87 7 S ~-Globulin skin-sensitizing activity," 1041 Glomerular basement membrane, human, proper-

ties of, 517 Godek, Geraldine, 692 Goitein, Ruth, 323 Gold, Eli, 6~3, 692 Goldstein, Gerald, 225, 230 Golub, Edward S., 1060 Graft rejection in offspring of immunized mothers,

929 Granuloma formation, 959 Grayston, J. Thomas, 19 Grunert, R. R., 1090 Gudnad6ttir, Margr4t, 1116

Hackman, Robert, 1023 Halliday, R., 510 HaIIiday, W. J., 109, 141 Hamlin, M., 214 Hampil, Bettylee, 895 Hapten specific immune systems, problems en-

countered in double diffusion analysis of, 1067, 1074

- - systems, anomalous spur formation in, 1074 Harter, Donald H., 730 Havlick, M. J., 422 tIeise, E. R., 125 Hemagglutination, enterovirus, inhibition of, 1111 Hemagglutinin production, kinetics of, 368 - - titer, influenza virus, measurement of, 336 I-Iemocyanin, immunochemieal studies of, 141

Hemolysin response, role of liver and appendix in, 306

- - t i tration by C'I fixation, 559 Hemolytic complement, a new component of, 355 Henle, Gertrude, 118 Henle, Werner, 118 Herndon, Betty L., 966 Herpes simplex, studies, 635 - - - virus, studies, 181, 189 Herpes zoster virus, characteristics of, in vitro,

683 Higginbotham, R. D., 867 Hiramoto, R. N., 214 Histamine-sensitizing factor of BordeteIla pertus-

sis, 643 - - toxicity, circulatory collapse in, 1 Ho, Helen H., 54 Hocker, N. D., 887 Hoffman, C. E., 1090 Hokama, Y., 156 Hoppe, Immo, 466 Host-virus interaction in visna-lnfected sheep,

1116 Hsiung, G. D., 591 Hu, C. C., 834 Hubbert, William T., 759 Hurlimann, Jean, 765 Hydrolase levels in alveolar macrophages, 125 Hypersensitivity, delayed, antigeni c specificity

in, 331 - - , flea bite, role of collagen in, 162 - - , Jones-Mote, in mice, 834 - - , role of lysosomes in, 1060 Hypothermia, effect of, on systemic anaphylaxis,

621

IgG Skin-sensitizing activity, 1041 Iida, Tsuyoshi, 1129 Immune diffusion, comparative, at gelatin-agar

interfaces, 704 - - responses, enhancement of, by a booster in-

jection of Coccidioides spherules, 1048 Immunity, antigens in, 665 - - , enhancement of, to C. immitis infection, 1048 Immunization, response to, 781 - - , studies in, 846 Immunodiffusion, agar interaction in, 156 Immunofluorescence for typing rickettsia strain,

1129 Immunoglobulin, allergen binding by, 937 - - in the skin, 951 - - of mice, 781 - - sequence, 345 7G-Immunoglobulin allotypes, altered phenotypic

expression of, 525 - - - - and purified anti-hapten antibodies, dis-

tribution of allelic allotypes among, 404 - - - - , distribution of allelic allotypes among, 404

1965] INDEX 1179

-----, two distinct, in mice, 823 Immunologic unresponsiveness to contact sensi-

tizers, 397 Immunosuppression, by acriflavine or dietary

restriction, 1013 Inclusion bodies, intranuclear, development in

measles virus infection, 840 Influenza virus, A1, surface properties of, 387 - - - growth and antibody response in amanta-

dine-treated mice, 1090 - - hemagglutinin, measurement of, 336

Inoue, Kozo, 355 Interferon action, inhibition of, by puromycin,

696 Intrinsic factor autoantibody, 536 5-Iodo-2-deoxyuridine, antiviral dynamics of, 635 Isakovi5, Katarina, 602 Ishizaka, Kimishige, 197, 771 Ishizaka, Teruko, 197, 771 ~A IsoaggIutinin, immunochemical properties of,

771 Isoantibodies, altered expression of "rG aUotypes

in rabbits exposed to, 525 - - and the red cell antigens they identify, 148 Isoantigens on human tissue culture cell lines, 494 Isohemaggtutinin, production after sublethal ir-

radiation, and rejection of allogeneie skin grafts, 945

"yA Isohemagglutinin, immunochemical proper- ties of, 197

Isothiocyanate, fluorescein, and its protein con- jugates, chemical and physical variables affecting, 1165

Jawetz, Ernest, 635 Jenness, Cornelia P., 487 Jones, V. E., 331 Jones-Mote hypersensitivity in mice, 834

Kawamura, Akiyoshi, 1129 Kawashima, Hosaku, 1129 Kearney, R., 109 Kenny, George E., 19 Kidney proteins, relation of rat urinary proteins

to, 574 Kinetics, cellular, of phagocytic cells, 1134 Kirchstein, R. L., 743 Kitagawa, Masayasu, 446,455, 991 Klugerman, Maxwell R., 1165 Kobayashi, Yuzuru, 412 Kong, Yi-Chi M., 1048 Kopp, William L., 937 Kraft, Sumner C., 314, 1013 Kronman, Barry S., 13

Lackovid, ¥., 387 Lane, Joseph M., 621

Lanzieri, Mario, 651 Lark, Cynthia A., 404 Larrivee, D. H., 162 Latex particulate carriers, adjuvant action of,

1147 Latham, William C., 487 Lazda, Velta, 254 Leake, E. S., 125 Lectins, EDTA inhibition of RBC agglutination

by, 876 Lee, Evelyn H., 197, 771 Lennette, Edwin H., 54 Leonard, Martha R., 466 Lepow, Irwin H., 1080 Leptospira biflexa, nature of antibodies synthe-

sized during immune response to, 887 Leptospira icterohemorrhagiae, ~,-irradiated, im-

munogenicity of, 759 Leptospirosis, experimental, immunity in, 759 Lerner, A. Martin, 1111 Leskowitz, Sidney, 331, 846 Levine, H. B., 1048 Levine, Leo, 643 Lewis, F. Bruce, 501 Lewis, L. J., 1057 Ley, Herbert L., Jr., 487 Lieberman, Rose, 823 Limpet, giant keyhole, immunochemical studies

of, 141 Limulus polyhemus, immunochemical studies of,

141 Linscott, William D., 546 Litt, Mortimer, 1153 Litwin, Stephen D., 1147 Liu, Chien, 840 Liver factor, transplantation antigen, destruc-

tion by, 673 --, role in hemolysin response, 306 Llanes-Rodas, Rizalina, 840 Locke, R. F., 480 Lofy, Mary F., 418 Lowney, Edmund D., 397 Lymph node cells, single, producing heteroclitic

bacteriophage antibody, 378 Lymphocyte fraction of the peritoneal fluid cell

population, association of immunologic de- termination with, 288

Lymphoid cells in thymectomized rats, 602 Lysosomes, role of, in hypersensitivity, 1060

Macaca mulatta, antibody response of, to eoxsackie- viruses, 54

Mackenzie, M. R., 87 MaePherson, Catherine F. C., 629 Maerophages, alveolar, effect of bacillus Cal-

mette-Gu6rin in, 125

1180 INDEX [voL. 95

- - , peritoneal, suppression of tumor growth by, 656

Mage, Rose, 525 Makel~, O., 378 Makinodan, T., 466 Malley, Arthur, 141 Mandel, Mark A., 673 Mandy, William J., 501 Mast cells and resistance to Russell 's viper venom,

867 Maurer, Paul H., 1095 McDuffie, Frederic C., 614 McLaughlin, Carla L., 781 McLean, I. W., Jr., 422 Measles infection, immunofluorescent study, 840

virus, effect of mitomycin C on, 753 - - vaccine, inactivated, 1057

Megathura crenulata, immunochemical studies of, 141

Melnick, Joseph L., 9, 895 Mercaptoethanol-sensitive antibody production

in germ-free mice and guinea pigs, 300 6-Mercaptopurine, arrest of immunoglobulin se-

quence by, 345 Messenger RNA, stabil i ty of, in antibody syn-

thesis, 254 Metabolism of synthetic polypeptides, 794, 804 Metzgar, Richard S., 494 Meyer, H. M., Jr. , 743 Miehaeli, D., 162 Michelsen, Christopher B. H., 487 Microimmunologic analyses, 966 Midulla, Mario, 9 Miller, Gall Lorenz, 336 Miller, James N., 759 Mitomycin C, effect on measles virus, 753 Monaco, Anthony P., 673 Morita, Toshiteru, 1134 Morse, Jane H., 722 Mowbray, James F., 794 Munoz, J., 1 Muramatsu, Shigeru, 1134 Mycoplasma pneumoniae, complement-fixing an-

tigen, 19 ~,-Myeloma proteins, aggregation of, 722 Myrvik, Q. N., 125

Nachman, Ralph L., 295 Nelson, Robert A., Jr., 355 Nephritis induced by sheep anti-human glomeru-

lar basement membrane sera, 517 Newcomb, Richard W., 583 Nishi, Ichiro, 614 Nossal, G. J. V., 665

Oikawa, Tatsuro, 614 Okumoto, Masao, 635 Ovary, Zoltan, 113, 765

Pagano, Joseph S., 909 P~lsson, P~ll A., 1116 Paneic, F., 1057 Papain-digested chicken ~,-globulin, 855 Papermaster, David S., 794, 804 Papovavirus and adenovirus, interrelationship,

422 Parainfluenza virus type 5, experimental infec-

tion of, 591 Parkman, P. D., 743 Patterson, Roy, 48 Paul, William E., 1067, 1074 Peritoneal fluid ceil population, association of

immunologic determination with the lympho- cyte fraction of, 288

Peterson, W. Peter, 959 Phagocytic cells, cellular kinetics of, in immu-

nized, x-irradiated mice, 1134 Phagocytosis of tumor cells in vitro, 80 Phase variation in Coxiella burneti, 880 Phillips, P. E., 743 Pieroni, Robert E., 643 Piraino, F. F., 1107 Plaque formation by sensitized oral mucosal cells,

209 Poliovirns, antigenic differentiation of, by ab-

sorbed hyperimmune sera, 171 - - , bovine serum inhibitor of, 909 - - , quantitative complement fixation with, 70 - - strains, at tenuated and neurovirutent, adsorp-

tion of, to neural tissue, 730 Poly-a-amino acids, antigenicity of, 1095 Polymers, enantiomorphic, metabolic fate of, 794 Polymorphonuclear neutrophil lysosomes, tissue

damage by, 1060 Polypeptide, antigenicity of, 1095 - - antigens, synthetic, 542 - - chains, frequency distribution of, in human

tissue, 246 - - . synthetic, metabolism of, 794, 804

, , serum binding of, 804 -~-Polypeptide chain characteristics of human

IgG, skin-sensitizing activi ty related to~ 1041 Polysaccharide antigens, test for, 704 Potter, Michael, 823 Precipitin lines, dual, in single hapten systems,

1067 Pressman, David, 446,455, 991 Proflavine, immunosuppressant effects of, 314 - - , synthesis of Sendal virus in presence of, 791 /~-Propiolactone and ultraviolet light, inactiva-

tion and antigenicity of foot-and-mouth dis- ease virus by, 1100

Protein antigens, mercaptoethanol-sensitive 7 S antibodies to, in mouse antisera, 39

- - - - , test for, 704 - - , Bence-Jones, subtypes of, 295

1965] INDEX 1181

- - conjugates of fluorescein isothioeyanate, chemi- cal and physical variables affecting, 1165

- - , C-reactive, apparent diffusion constant of, 156 - - , 7-myeloma, aggregation of, 722 - - , rat urinary, immunochemical study, 574

, , relation to serum and kidney proteins, 574

- - , serum, alterations in toxoplasmosis, 1023 , , binding of synthetic polypeptides to, 804

- - , urinary, major, chromatographic separation of, 574

Pruzansky, Jacob J., 48 Psittacosis virus antibodies in domestic pigeons,

1107 Puromycin, inhibition of interferon action by, 696

Rabbi t agglutinator factor, 273 Ragweed antigens, homogeneity of, 48 Rannon, L., 171 Rapp, Fred, 753 Rapp, Herbert J., 559 Rathov~, V., 387 Reactivity, immunologic, in thymectomized rats

receiving competent lymphoid cells during immunization, 602

Reduction, effect on 7A isoagglutinin, 771 Reed, Charles E., 937 Remington, Jack S., 1023 Resistance, natural, to group A streptococci, 131 Response, primary, anti-protein antibodies dur-

ing, 981 Restriction, dietary, immunosuppression by, 1013 Rheumatoid factor, reactivi ty of, with rabbit

7-globulin, 614 Rickettsia orientalis, complement-fixing antigen

of, 412 Rickettsia strain, immunofluorescence for typing,

1129 Riley, Richard F., 156 Ringle, David A., 966 RNA, messenger, stabili ty of, in antibody syn-

thesis, 254 Rous, virus, blocking effect of West Nile virus on

production of sarcoma by, 1121 Rubella virus infection, experimental, 743 Runt disease, modification of, by treatment with

lyophilized tissues, 323 Russell, Paul S., 673 Russell's viper venom, mast cells and resistance

to, 867 Russell, Warren J., 1142

Sado, Toshihiko, 466 Saffran, Murray, 629 Saha, Anil, 141 Sahiar, Khurshed, 345 Salmonella adelaide flagellin, immunologic toler-

ance to, 665

Salmonella typhosa infection, intracerebral, 567 Salvaggio, John E., 846 Samloff, I. Michael, 536 Samuelson, Joel S., 314, 1013 Sarcoma production, blocking effect of West Nile

virus on, by Rous virus, 1121 Savage, D. C., 1048 Schistosoma mansoni cercariae, immunochemistry

of, 13 Schistosome antigen in pseudotubercle, 959 Schlesinger, Michael, 323 Schmidt, Nathalie J., 54 Schultz, Richard, 635 Schwartz, Robert S., 345 Sedwick, W. David, 909 Segre, D., 480 Sell, Stewart, 300 Sendai virus, synthesis in presence of proflavine,

791 Sensitizers, contact, immunologic unresponsive-

ness after topical application of, 397 Serafini, A., 422 Serum albumin specificity, anti-bovine, and bind*

ing affinity after termination of tolerance to bovine serum albumin, 546

- - , anti-human glomerular basement membrane, nephritis induced by, 517

binding of synthetic polypeptides, 804 - - , bovine, inhibitory, interaction with poliovirus,

909 factor, new, in normal rabbits, 501 hemolysin response, roles of liver and appendix

in, 306 - - , human, distribution of precipitating antibodies

among, 181 - - , hyperimmune, antigenic differentiation of

polioviruses by, 171 k , immune, heteroclitie antibody in, 378 k , normal, bactericidal action of, on Gram-

negative bacteria, 75 protein alterations in toxoplasmosis, 1023

, relation of rat urinary proteins to, 574 Shaffer, Morris F., 567 Sharp, D. G., 737 Shinomoto, Tak T., 54 Shirodkax, Manohar V., 1121 Singer, Jacques M., 1147 Sirisinha, St i taya, 918 Siskind, Gregory W., 436 Skin grafts, allogeneie, and production of iso-

hemagglutinins after sublethal irradiation, 945

---sensitizing act ivi ty related to 7-polypeptide chain characteristics of human IgG, 1041

Small, Parker A., Jr., 282 Smith, Kendall O., 810 Sohmura, Yasunobu, 1134 Sonnabend, Joseph A., 696

1182 INDEX [voL. 95

Spiegelberg, It. L., 1034 Spitznagel, John K., 1060 Spleen cells, nonimmune, conversion to antibody-

forming cells by RNA, 583 Splenectomy, restitution of immunoglobulin by,

345 Spur formation in hapten systems, 1074 Starr, Jason L., 254 Stastny, Peter, 929 Stavitsky, A. B., 981 Steblay, Raymond William, 517 Stein, Stefan, 295 Stewart, P. Brian, 314 Stollerman, Gene H., 131 Streptococci, group A, natural resistance to, 131 Suh, Inn Soo, 567 Sussdorf, Dieter H., 306 Synthesis of Sendal virus in presence of proflavine,

791

Tachibana, Nobuyoshi, 412 Tempelis, C. H., 418 Terry, William D., 1041 Tetanus antibodies and sheep diphtheria, hetero-

geneity of, 480 - - toxoid and toxin, purification and characteriza-

tion, 487 - - --, fractionation of, by gel filtration, 487 Tetramethylrhodamine-immune globulin conju-

gates, chromatographic purification of, and their use in the cellular localization of rabbit 7-globulin polypeptide chains, 230

Thompson, S. H., 225 Thonard, John C., 209 Tillotson, James R., 1111 Timperi, Ralph J. K., 487 Tissot, Robert G., 148, 273 Tissue culture, canine renal, effect of storage on

vaccine prepared in, 1057 - - - cell lines, isoantigens on, 494 - - damage by polymorphonuclear neutrophil

lysosomes, 1060 --, human, distribution of polypeptide chains in,

246 --, lyophilized, in treatment of runt disease, 323 --, neural, adsorption of poliovirus to, 730 Tokumaru, Tadasu, 181, 189 Tolerance, acquired immunologic, inhibition of,

by actinomycin, 718 --, immunologic, to Salmonella adelaide flagellin,

665 - - to bovine serum albumin, termination of, 546 Toxoplasmosis, serum protein alterations in, 1023

Transplantation antigen factor, 673

Tremblay, Armand, 574 Trousdale, Melvin, 810

destruction by liver

Tsutsugamushi disease rickettsia, immunofluores- cence for typing of, 1129

Tumor growth suppression by isolated peritoneal macrophages, 656

Tunis, Marvin, 876 Tyan, Marvin L., 945

Uryvayev, L. V., 791

Vaccine, measles virus, inactivated, 1057 Vaccinia virus particles, agglutination of, 737 Vanderslice, Darlena, 753 Varicella virus, characteristics of, in vitro, 683 ---zoster complement fixation, 692 Vaughan, John H., 918 Venom, Russell's viper, mast cells and resistance

to, 867 Vibrio fetus antibody in bovine serum, 1002 Virus, influenza, growth and antibody response

in amantadine-treated mice, 1090 p , A1 influenza, surface properties of, 387 - - preparations, enterovirus immunizing antigens

in the form of, 9 --,Sendai, synthesis of, in presence of proflavine,

791 vaccine, inactivated measles, 1057

Visna-infected sheep, host-virus interaction in, 1116

yon Lichtenberg, Franz, 959

Waksman, Byron H., 602 Wallis, Craig, 9, 895 Wedgwood, Ralph J., 75 Weigle, William O., 546, 1034 Weiler, Eberhardt, 288 Weiler, Ivan Jeanne, 288 Wennersten, Christine, 602 West Nile virus, blocking effect of, on production

of sarcoma by Rous virus, 1121 Winnicki, E., 1057 Winter, A. J., 1002 Wood, B. T., 225

Yagi, Yasuo, 446, 455, 991

Zhdanov, V. M., 791 Zimmering, Paula E., 262 Zipilivan, E. Mario, 487 Zmijewski, Chester M., 494

Just out 3rd European Conference

on M icrocirculation

Jerusalem 1 ~

edited by--H. HARDER$, Hamburg

X + 606 p., 299 fig., 2 cpl., 44 tab., 1965. (Bibliotheca Anatomic.a, Fasc. 7) sFr./DM t65.~/£14.8.9./US $39.60

Index I. Opening Session--IL Small Blood Vessel ReactbAty--lll. Microcirculation of Lung--IV. Microcirculation of Eye-o-V. Capillary Permeability--VI. Red Cell Sedimentation and Aggregation-- VII. Special Aspects of Capillary Perrneability~--Vlll. Capillary Fragility--IX. Low Molecular Weight Dextrans--X. Special Studies on Peripheral Circulation--Xl. Small Blood Vessel WalI--XIi. Biorheology- XIII. Blood Flow and Lymph Flow°-.XIV. Trauma and Shock--XV. Microcirculation in Special Clinical States--~XVl. Small Ve~ls in Osler's Disease, Diabetes and Some Vascular Dis- eascs--XVll. Physiopharmacological Studies on the Human Microcirculation.

Der vorliegende Band ist der ~ t t e in der Reihe der Verhandlungsb~inde tier 1959 gegriindeten Euro- p~iischen Gesellschaft ffir M~ozirkulation, die ihre Tagungen in 2j~ihrigen Abst~inden abhalt (1960 Hamburg. Vorsitz: Prof. Dr. HARALD HAgDE~, Bibliotheca Anatomica, Fasc. 1, 1961; 1962 Pavia, Vorsitz; Prof. Dr. GIUSEPPE ~Lt.~RINI, Bibliotheca Anatomica, Fasc. 4, 1963). Die Abhandlungen befassen sich mit der Physiologie, Pathologie und Klinik der terminalen Strombahn sowie physikali- schen Problemen biologischer Str6mungsvorgange (Biorheologie). Die Reihe wird unter dem Titel ~,Advances in Microeirculation~, herausgegeben yon H. HARDERS, Hamburg, tbrtgesetzt werden mit den Berichten iiber die niichsten Tagungen (19~ Cambridge, Vorsitz: Prof. Dr. GORDON SANDERS. 1968 G6teborg, Vorsitz: Prof. Dr. LAI~ ~IK GEL1N). Physiologen, Pathologen~ Kliniker und tierexperimentelle Forscher werden in den angefiahrten B~nden eine ersch6pfende i3bersicht O~r den gegenwiirtigen Stand der Forschung auf dem Gebiete derEndstrombahn finden. Von txsonderer ~deutung for den Kliniker sind Methoden zur Funktions- diagnostik der feinsten Gefiissabschnitte, die auch in dem zu dieser Reihe geh6renden Band <~Sym- posion on Microvascular Methodology~ 1964, herausgegeben von Prof. Dr. PER-INGVAR BR~,NE- MARK, G6teborg, Bibliotheca Anatomica, Fasc. 5, 1965, behandelt werden. Die neusten Methoden und Ergebnisse auf dem Gebiete der AustauschwJrg~inge, Gef~isspermeabilitiit, Gefiissfragilit~it, Str6mungs- und Durchblutungsn~ssung im KapiUarbereich und iiber die klinische Biomikroskopie sind hier zusammengefasst. In den zukiinftigen B~inden der Rei~ ~Advances in Microcirculation, werden klinisch bedeutsame Hauptthemen wie: Pharmakologie tier Endstrombahn, Gewebs.reaktionen, Transplantation, Tumor- zirkulation, thromboembolische Erkrankungen und Schockprobleme behandelt werden.

S. KARGER AG, Arnold-Bi~cklin-Strasse 25, Basel (Switzerland)

Please send me: Copy/ies 3rd Conference on Microcirculation

Name

Address

Please place your order with your agent or:

Albert J. PHIEBIG, P.O. 352, White Plains, N.Y.

AGAR,

r for precise

MICROBIOLOGICAL IMMUNO-DIFFUSION

&

ELECTROPHORETIC procedures

Literature on requesl

D I F C O L A B O R A T O R I E S D E T R O I T M I C H I G A N U S A

Q U A L I T Y A N D S E R V I C E S I N C E 1 8 9 5