Index 2004, Volume 34 (pages 1–3732)

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Author Index III

z • ¶ , - ˜ 2 ¥ k \ …

" - ˚ O r A f p j j A fi

Abe, M., see Wen, X.Abrahamsen, H., see Vang, T.Abramson, J., see Medgyesi, D.Abrignani, S., see Masciopinto, F.Accapezzato, D., see Francavilla, V.Accapezzato, D., Francavilla, V., Rawson,

P., Cerino, A., Cividini, A., Mondelli, M.U. and Barnaba, V. Subversion of effectorCD8+ T cell differentiation in acute hepa-titis C virus infection: the role of thevirus . . . . . . . . . . . . . . . . . . . . . . . . . . 438

Acha-Orbea, H., see LeibundGut-Landmann, S.

Achdout, H., see Gazit, R.Achdout, H., see Markel, G.Adams, V. C., Hunt, J. R. F., Martinelli, R.,

Palmer, R., Rook, G. A. W. and Brunet,L. R. Mycobacterium vaccae induces apopulation of pulmonary CD11c+ cellswith regulatory potential in allergic mice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 631

Adhikary, D., see Mautner, J.Adkins, B., Jones, M., Bu, Y. and Levy, R.

B. Neonatal tolerance revisited again:specific CTL priming in mouse neonatesexposed to small numbers of semi- or fullyallogeneic spleen cells . . . . . . . . . . 1901

Adner, M., see Bachar, O.Aebischer, T., see Misslitz, A. C.Agace, W. W., see Ericsson, A.Agaugue, S., see Perrin-Cocon, L.Agostini, M., see Ronchetti, S.Aguado, E., see Caparros, E.Aguilar, D., see Hernandez-Pando, R.Aguilar, H., see Alvarez-Errico, D.Aizawa, Y., see Palaniyandi, S. S.Ajuebor, M. N., Hogaboam, C. M., Le, T.,

Proudfoot, A. E. I. and Swain, M. G.CCL3/MIP-1 § is pro-inflammatory inmurine T cell-mediated hepatitis byrecruiting CCR1-expressing CD4+ T cellsto the liver . . . . . . . . . . . . . . . . . . . . 2907

Akadegawa, K., see Sato, T.Akasaki, Y., see Liu, G.Akbari, O., see Stock, P.Akira, S., see Vossenkämper, A.Aktories, K., see Averbeck, M.Alard, P., Clark, S. L. and Kosiewicz, M. M.

Mechanisms of tolerance induced byTGF g -treated APC: CD4 regulatory T cellsprevent the induction of the immuneresponse possibly through a mechanisminvolving TGF g . . . . . . . . . . . . . . . . 1021

Alber, G., see Vossenkämper, A.Alcaide, P. and Fresno, M. AgC10, a mucin

from Trypanosoma cruzi, destabilizes TNFand cyclooxygenase-2 mRNA by inhibit-ing mitogen-activated protein kinasep38 . . . . . . . . . . . . . . . . . . . . . . . . . 1695

Alcaıs, A., see Feinberg, J.

Aldemir, H., see Hansasuta, P.Alexander, J., see Cunningham, A. F.Alexander, S. I., see Wu, H.Alfano, M., see Rizzi, C.Alizadeh, M., see Birebent, B.Allen, J. E., see Heasman, S. J.Allen, R. A., see Tian, Y.Allenbach, C., see Tacchini-Cottier, F.Alli, R., Savithri, B., Das, S., Varalakshmi,

C., Rangaraj, N. and Khar, A. Involve-ment of NKR-P2/NKG2D in DC-mediatedkilling of tumor targets: indicative of acommon, innate, target-recognition para-digm?. . . . . . . . . . . . . . . . . . . . . . . . 1119

Allman, D., see Monroe, J. G.Alon, R., see Franitza, S.Alsaati, T., see Xystrakis, E.Alt, R., see Seidel-Guyenot, W.Altenberend, F., see Dengjel, J.Altman, A., Kaminski, S., Busuttil, V.,

Droin, N., Hu, J., Tadevosyan, Y., Hips-kind, R. A. and Villalba, M. Positive feed-back regulation of PLC + 1/Ca2+ signalingby PKC D in restimulated T cells via a Teckinase-dependent pathway. . . . . . . 2001

Altmann, D. M., see Ellmerich, S.Alvarado-Esquivel, C., see Vossenkämper,

A.Alvarez-Errico, D., Aguilar, H., Kitzig, F.,

Brckalo, T., Sayos, J. and Lopez-Botet,M. IREM-1 is a novel inhibitory receptorexpressed by myeloid cells . . . . . . . 3690

Amarzguioui, M., see Vang, T.Ameglio, F., see Rutella, S.Amigorena, S., see Gil-Torregrosa, B. C.Amiot, L., see Le Rond, S.Amiot, M., see Gomez-Bougie, P.Amor, S., see Ellmerich, S.Amoroso, M. G., see Nolte-‘t Hoen, E. N.

M.Amrani, Y. M., Voegtle, D., Barbier, E., Six,

A. and Cazenave, P.-A. Marginal zone Bcell enrichment and strong follicular B cellreduction correlate with a delayed IgGresponse in a light chain diversityrestricted mouse model. . . . . . . . . . 2812

Anders-Bartholo, P., see Oflazoglu, E.Andersen, M. H., see Eggert, A. O.Anderson, R. M., see Ludewig, B.Andersson, A.-C., Seppälä, U. and Rudin,

A. Activation of human neonatal monocyte-derived dendritic cells by lipopolysaccha-ride down-regulates birch allergen-inducedTh2 differentiation. . . . . . . . . . . . . . . 3516

Andersson, U., see Harris, H. E.Anderton, S. M., see Hochweller, K.Andre, P., Castriconi, R., Espeli, M.,

Anfossi, N., Juarez, T., Hue, S., Conway,H., Romagne, F., Dondero, A., Nanni, M.,Caillat-Zucman, S., Raulet, D. H., Bot-

tino, C., Vivier, E., Moretta, A. and Paul,P. Comparative analysis of human NK cellactivation induced by NKG2D and naturalcytotoxicity receptors . . . . . . . . . . . . 961

Andre, P., see Perrin-Cocon, L.Andres, P. G., see Loser, K.Andrieux, K., see de Kozak, Y.Anfossi, N., see Andre, P.Antczak, D. F., see Takahashi, T.Antoni, G., see Feinberg, J.Aparicio, P., see Caparros, E.Apelt, J., see Loser, K.Appel, H., see Ferlin, W. G.Arancibia-Carcamo, C. V., Osawa, H.,

Arnett, H. A., Haskova, Z., George, A. J.T., Ono, S. J., Ting, J. P.-Y. and Streilein,J. W. A CIITA-independent pathway thatpromotes expression of endogenousrather than exogenous peptides inimmune-privileged sites . . . . . . . . . . 471

Araujo, L. M., Lefort, J., Nahori, M.-A.,Diem, S., Zhu, R., Dy, M., Leite-de-Moraes, M. C., Bach, J. F., Vargaftig, B.B. and Herbelin, A. Exacerbated Th2-mediated airway inflammation and hyper-responsiveness in autoimmune diabetes-prone NOD mice: a critical role for CD1d-dependent NKT cells. . . . . . . . . . . . . 327

Arce, I., Martınez-Munoz, L., Roda-Navarro, P. and Fernandez-Ruiz, E. Thehuman C-type lectin CLECSF8 is a novelmonocyte/macrophage endocytic recep-tor . . . . . . . . . . . . . . . . . . . . . . . . . . . 210

Arck, P. C., see Zenclussen, A. C.Arendse, B., see Uyttenhove, C.Arizono, N., see Kato, T.Arkesteijn, G. J. A., see Nolte-‘t Hoen, E.

N. M.Arlettaz, L., Degermann, S., Rham, C. D.,

Roosnek, E. and Huard, B. Expression ofinhibitory KIR is confined to CD8+ effectorT cells and limits their proliferative capac-ity . . . . . . . . . . . . . . . . . . . . . . . . . . . 3413

Arlettaz, L., Villard, J., de Rham, C., Deger-mann, S., Chapuis, B., Huard, B. andRoosnek, E. Activating CD94:NKG2Cand inhibitory CD94:NKG2A receptors areexpressed by distinct subsets of commit-ted CD8+ TCR § g lymphocytes. . . . 3456

Arnett, H. A., see Arancibia-Carcamo, C. V.Arnold, B., see Ganss, R.Arnon, T. I., see Gazit, R.Arnon, T. I., see Markel, G.Arya, A., see Ericsson, A.Asadullah, K., see Jung, M.Astoul, E., see Laurence, A.Attali, G., Gancz, D. and Fishelson, Z.

Increased sensitivity of early apoptoticcells to complement-mediated lysis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3236

IV Author Index

Auriault, C., see Pajot, A.Ausiello, C. M., see Fedele, G.Averbeck, M., Braun, T., Pfeifer, G., Slee-

man, J., Dudda, J., Martin, S. F., Kremer,B., Aktories, K., Simon, J. C. and Ter-meer, C. Early cytoskeletal rearrangementduring dendritic cell maturation enhancessynapse formation and Ca2+ signaling inCD8+ T cells. . . . . . . . . . . . . . . . . . . 2708

Aversa, G., see Beinhauer, B. G.Avidan, H., Kipnis, J., Butovsky, O., Caspi,

R. R. and Schwartz, M. Vaccination withautoantigen protects against aggregatedg -amyloid and glutamate toxicity by con-trolling microglia: effect of CD4+CD25+ Tcells . . . . . . . . . . . . . . . . . . . . . . . . . 3434

Avniel, S., see Wald, O.Aydar, Y., Wu, J., Song, J., Szakal, A. K.

and Tew, J. G. Fc + RII expression on follic-ular dendritic cells and immunoreceptortyrosine-based inhibition motif signaling inB cells . . . . . . . . . . . . . . . . . . . . . . . . . 98

Ayroldi, E., see Ronchetti, S.Bach, J. F., see Araujo, L. M.Bachar, O., Adner, M., Uddman, R. and

Cardell, L.-O. Toll-like receptor sti-mulation induces airway hyper-responsiveness to bradykinin, an effectmediated by JNK and NF- ‹ B signalingpathways . . . . . . . . . . . . . . . . . . . . . 1196

Bachmann, M. F., Hunziker, L., Zinkerna-gel, R. M., Storni, T. and Kopf, M. Main-tenance of memory CTL responses by Thelper cells and CD40-CD40 ligand: anti-bodies provide the key . . . . . . . . . . . 317

Bäckström, B. T., see Petersen, T. R.Bae, Y.-S., see Lee, S.-Y.Baeza, I., Leyva, E., Campos, B., Lara, M.,

Ibanez, M., Farfan, N., Orozco, H.,Flores-Romo, L., Hernandez-Pando, R.and Wong, C. Antibodies to non-bilayerphospholipid arrangements induce amurine autoimmune disease resemblinghuman lupus . . . . . . . . . . . . . . . . . . . 576

Bai, C., see Tumang, J. R.Baker, D., see Ellmerich, S.Balde, R., see Feinberg, J.Balic, A., Harcus, Y., Holland, M. J. and

Maizels, R. M. Selective maturation ofdendritic cells by Nippostrongylusbrasiliensis-secreted proteins drives Th2immune responses . . . . . . . . . . . . . 3047

Ball, J., see Cunningham, A. F.Ballesteros, A., see Carvalho-Pinto, C.Balling, R., see Luckow, B.Balomenos, D., see Carvalho-Pinto, C.Banchereau, J., see Pulendran, B.Bansal-Pakala, P., see Pakala, S. V.Baratin, M., Bonin, K. and Daniel, C. Front-

line: Peripheral priming of alloreactive Tcells by the direct pathway of allorecogni-tion. . . . . . . . . . . . . . . . . . . . . . . . . . 3305

Barbarat, B., see Duhen, T.Barbat, C., see Trucy, M.Barbier, E., see Amrani, Y. M.Barclay, A. N., see Hassan, N. J.Barclay, A. N., see Hatherley, D.

Bardoni, B., see Mayne, M.Barington, T., see Galle, P.Barnaba, V., see Accapezzato, D.Barnaba, V., see Francavilla, V.Barnes, E., Ward, S. M., Kasprowicz, V. O.,

Dusheiko, G., Klenerman, P. and Lucas,M. Ultra-sensitive class I tetramer analysisreveals previously undetectable popula-tions of antiviral CD8+ T cells . . . . . 1570

Barouch, D. H., see McKay, P. F.Barth, R. K., see Kuzin, I. I.Bartsch, B., see Feterowski, C.Basta, S., see Chen, W.Bataille, R., see Gomez-Bougie, P.Bauer, S., see Rutz, M.Baumann, R., Yousefi, S., Simon, D., Rus-

smann, S., Mueller, C. and Simon, H.-U.Functional expression of CD134 by neu-trophils. . . . . . . . . . . . . . . . . . . . . . . 2268

Baumann, S., see Li-Weber, M.Baumann, S., Kyewski, B., Bleckmann, S.

C., Greiner, E., Rudolph, D., Schmid, W.,Ramsay, R. G., Krammer, P. H., Schütz,G. and Mantamadiotis, T. CREB functionis required for normal thymic cellularityand post-irradiation recovery . . . . . 1961

Beat, R., see Vollstedt, S.Beaudoin, L., see Ferlin, W. G.Beaudoin, L., see Stenström, M.Beauplet, A., see Birebent, B.Becker, C., see Stassen, M.Becker, J. C., see Eggert, A. O.Becker, K. G., see Mayne, M.Beermann, F., see Tardivel, A.Befus, A. D., see Dery, R. E.Behrends, J., see Fernekorn, U.Behrends, U., see Mautner, J.Beider, K., see Franitza, S.Beider, K., see Wald, O.Beilke, J., see Wheat, W.Beinhauer, B. G., McBride, J. M., Graf, P.,

Pursch, E., Bongers, M., Rogy, M., Kor-thauer, U., de Vries, J. E., Aversa, G. andJung, T. Interleukin 10 regulates cell sur-face and soluble LIR-2 (CD85d) expres-sion on dendritic cells resulting in T cellhyporesponsiveness in vitro . . . . . . . . 74

Beissert, S., see Bruder, D.Beissert, S., see Loser, K.Bell, S., see Erlandsson, L.Bell, S. E., Vigorito, E., McAdam, S.,

Reynolds, H. M., Caraux, A., Colucci, F.and Turner, M. PLC + 2 regulates Bcl-2levels and is required for survival ratherthan differentiation of marginal zone andfollicular B cells . . . . . . . . . . . . . . . . 2237

Bellgrau, D., see Lang, J. A.Bellora, F., see Falco, M.Bendtzen, K., see Galle, P.BenMohamed, L., see Zhu, X.Bennink, J. R., see Chen, W.Bensa, J.-C., see Chaperot, L.Benz, C., Heinzel, K. and Bleul, C. C. Hom-

ing of immature thymocytes to the sub-capsular microenvironment within the thy-mus is not an absolute requirement for Tcell development . . . . . . . . . . . . . . . 3652

Berenson, L. S., Farrar, J. D., Murphy, T. L.and Murphy, K. M. Frontline: Absence offunctional STAT4 activation despitedetectable tyrosine phosphorylationinduced by murine IFN- § ¡ ¡ ¡ ¡ ¡ ¡ 2365

Berg, I., see Storset, A. K.Berglöf, A., see Lindvall, J. M.Bernard, I., see Xystrakis, E.Bernert, K., see Holtmeier, W.Bernstein, C. N., see Mayne, M.Bettelli, E., see Petersen, T. R.Beuling, E., see Eldering, E.Beuneu, C., see Verhasselt, V.Beutler, B., see Weighardt, H.Bezzine, S., see Perrin-Cocon, L.Bi, M., see Tang, Q.Bianchini, R., see Ronchetti, S.Biedermann, B., see Zhang, J. Q.Bien-Gräter, U., see Hofmann, M.Bilenki, L., Yang, J., Fan, Y., Wang, S. and

Yang, X. Natural killer T cells contribute toairway eosinophilic inflammation inducedby ragweed through enhanced IL-4 andeotaxin production . . . . . . . . . . . . . . 345

Bilenki, L., see Han, X.Binda, E., see Mariani, M.Birebent, B., Lorho, R., Lechartier, H., de

Guibert, S., Alizadeh, M., Vu, N., Beaup-let, A., Robillard, N. and Semana, G.Suppressive properties of humanCD4+CD25+ regulatory T cells are depen-dent on CTLA-4 expression . . . . . . 3485

Bischoff, R., see Ehl, S.Black, K. L., see Liu, G.Blanchard, D., see Chaperot, L.Blanckaert, N., see Jeurissen, A.Blanco, P., see Pascal, V.Blankenstein, T., see Gladow, M.Blau, H., see Markel, G.Bleckmann, S. C., see Baumann, S.Bleul, C. C., see Benz, C.Blomberg, K. E. M., see Lindvall, J. M.Blondelle, S. E., see Hernandez, J.Blos, M., see Schleicher, U.Bluestone, J. A., see Tang, Q.Blum, A., see Elliott, D. E.Blumberg, R. S., see Markel, G.Blumenthal, S. G., see Probst, J.Boaz, P., see Wald, O.Bocharov, G., see Ludewig, B.Bode, U., Tiedemann, K. and Westermann,

J. CD4+ effector T cell distribution in vivo:TGF- g 1/TGF- g receptor II interactionduring activation mediates accumulationin the target tissue by preferential prolifer-ation. . . . . . . . . . . . . . . . . . . . . . . . . 1050

Boden, E. K., see Tang, Q.Bogdan, C., see Schleicher, U.Bogdan, C., see von Loewenich, F. D.Bohlender, J., see Velten, F. W.Boiocchi, M., see Sansonno, D.Boisson-Dupuis, S., see Feinberg, J.Boissonnas, A. and Combadiere, B. Inter-

play between cell division and cell deathduring TCR triggering . . . . . . . . . . . 2430

Boles, K. S., see Lee, J. K.Bonanno, C. T., see Dieli, F.

Author Index V

Bonanno, G., see Rutella, S.Bongers, M., see Beinhauer, B. G.Bonhagen, K., see Kretschmer, U.Bonhagen, K., see Misslitz, A. C.Bonin, K., see Baratin, M.Bonnet, E., see Pascal, V.Bonnotte, B., see Ghiringhelli, F.Boon, L., see de Vos, A. F.Boon, L., see Jeurissen, A.Boot, E. P. J., see Nolte-‘t Hoen, E. N. M.Bopp, T., see Stassen, M.Bories, J.-C., see Eyquem, S.Bornkamm, G. W., see Mautner, J.Bossuyt, X., see Jeurissen, A.Bosze, S., see Caccamo, N.Bottaro, A., see Kuzin, I. I.Bottino, C., see Andre, P.Bottino, C., see Falco, M.Bottino, C., see Moretta, A.Botto, M., see Cortes-Hernandez, J.Botto, M., see Yamada, M.Bourdet-Sicard, R., see Chapat, L.Bour-Jordan, H., see Tang, Q.Boursalian, T. E., see Dao, T.Bouvet, J.-P., see Oppezzo, P.Bouwman, L. H., see Roos, A.Boysen, P., see Storset, A. K.Boyton, R. J., see Ellmerich, S.Brady, H. J. M., see Granes, F.Braedel, S., see Scheel, B.Brandtzaeg, P., see Helgeland, L.Brasel, K., see Oflazoglu, E.Braud, V. M., see Hansasuta, P.Braun, T., see Averbeck, M.Brckalo, T., see Alvarez-Errico, D.Breitfeld, D., see Höpken, U. E.Breithaupt, C., see Mathey, E.Briand, J.-P., see Partidos, C. D.Briere, F., see Chaperot, L.Brocke, S., see Franitza, S.Broeren, C. P. M., see Nolte-‘t Hoen, E. N.

M.Brombacher, F., see Cunningham, A. F.Brombacher, F., see Han, S.Brombacher, F., see Uyttenhove, C.Bron, C., see Legler, D. F.Brooks, K. and Knight, A. M. Lowering the

affinity between antigen and the B cellreceptor can enhance antigen presenta-tion. . . . . . . . . . . . . . . . . . . . . . . . . . . 837

Brown, M. H., see Hassan, N. J.Bruder, D., Probst-Kepper, M., Westen-

dorf, A. M., Geffers, R., Beissert, S.,Loser, K., von Boehmer, H., Buer, J. andHansen, W. Frontline: Neuropilin-1: a sur-face marker of regulatory T cells. . . . 623

Brunet, C., see Pascal, V.Brunet, L. R., see Adams, V. C.Brunetto, M., see Masciopinto, F.Bruscoli, S., see Ronchetti, S.Bu, Y., see Adkins, B.Bueno, C., Lee, K. K., Chau, L. A., Lee-

Chan, E., Singh, B., Strejan, G. H. andMadrenas, J. Mechanism of modulationof T cell responses by N-palmitoylatedpeptides. . . . . . . . . . . . . . . . . . . . . . 3497

Buer, J., see Bruder, D.

Bugatti, A., see Rizzi, C.Bui, H., see Yang, J.-Q.Bunnell, S. C., see Seminario, M.-C.Burakoff, S. J., see Su, M. W.-C.Burrows, G. G., see Rich, C.Burrows, S. R., see Green, K. J.Busch, D. H., see da Costa, C. U. P.Bustamante, J., see Feinberg, J.Busuttil, V., see Altman, A.Butcher, E. C., see Fernekorn, U.Butler, J. E., see Holtmeier, W.Butovsky, O., see Avidan, H.Buzoni-Gatel, D., see Mennechet, F. J. D.Byrne, P., McGuirk, P., Todryk, S. and Mills,

K. H. G. Depletion of NK cells results indisseminating lethal infection with Borde-tella pertussis associated with a reductionof antigen-specific Th1 and enhancementof Th2, but not Tr1 cells . . . . . . . . . 2579

Cabrera-Poch, N., see Riol-Blanco, L.Caccamo, N., Meraviglia, S., La Mendola,

C., Bosze, S., Hudecz, F., Ivanyi, J.,Dieli, F. and Salerno, A. Characterizationof HLA-DR- and TCR-binding residues ofan immunodominant and genetically per-missive peptide of the 16-kDa protein ofMycobacterium tuberculosis . . . . . . 2220

Caccamo, N., see Dieli, F.Caillat-Zucman, S., see Andre, P.Callard, R., see Strid, J.Camozzi, M., see Rizzi, C.Campagnoli, S., see Masciopinto, F.Campos, B., see Baeza, I.Canella, A., see Link, C.Cantoni, C., see Vitale, C.Cantrell, D., see Laurence, A.Caparros, E., de Heredia, A. B., Carpio, E.,

Sancho, D., Aguado, E. and Aparicio, P.Aggregation of MHC class I molecules ona CD8+ § g T cell clone specifically inhibitsnon-antigen-specific lysis of targetcells . . . . . . . . . . . . . . . . . . . . . . . . . . . 47

Capoluongo, E., see Rutella, S.Caraux, A., see Bell, S. E.Cardell, L.-O., see Bachar, O.Cardell, S., see Stenström, M.Carlomagno, S., see Vitale, M.Carosella, E. D., see Le Rond, S.Carpio, E., see Caparros, E.Carralot, J.-P., see Scheel, B.Carvalho-Pinto, C., Garcıa, M. I., Gomez,

L., Ballesteros, A., Zaballos, A., Flores,J. M., Mellado, M., Rodrıguez-Frade, J.M., Balomenos, D. and Martınez-A., C.Leukocyte attraction through the CCR5receptor controls progress from insulitisto diabetes in non-obese diabeticmice. . . . . . . . . . . . . . . . . . . . . . . . . . 548

Casanova, J.-L., see Feinberg, J.Caspary, W. F., see Holtmeier, W.Caspi, R. R., see Avidan, H.Castellano, G., see Roos, A.Castriconi, R., see Andre, P.Cathelin, D., see Ghiringhelli, F.Cayota, A., see Oppezzo, P.Cazareth, J., see Ferlin, W. G.Cazenave, P.-A., see Amrani, Y. M.

Celada, A., see Comalada, M.Cella, M., see Coccia, E. M.Cerban, F. M., see Stempin, C. C.Cerino, A., see Accapezzato, D.Cerino, A., see Francavilla, V.Cerundolo, V., see Markel, G.Cerundolo, V., see Smith, D. C.Ceuppens, J. L., see Jeurissen, A.Chakraborty, N. G., see Chhabra, A.Chaloin, O., see Partidos, C. D.Chan, C.-C., see Chen, J.Chaneva, S., Schneider, G., Siegmund, D.,

Wajant, H., Mages, J. and Häcker, G.Enhanced basal AP-1 activity and de-regulation of numerous genes in T cellstransgenic for a dominant interferingmutant of FADD/MORT1 . . . . . . . . . 3006

Chang, H.-C., see Dogan, I.Chang, J.-H., see Su, M. W.-C.Chang, M.-C., see Cheng, W.-F.Chang, W.-S., see Chung, Y.Chang, Y.-C., see Lee, S.-Y.Chapat, L., Chemin, K., Dubois, B.,

Bourdet-Sicard, R. and Kaiserlian, D.Lactobacillus casei reduces CD8+ T cell-mediated skin inflammation . . . . . . 2520

Chaperot, L., Perrot, I., Jacob, M.-C.,Blanchard, D., Salaun, V., Deneys, V.,Lebecque, S., Briere, F., Bensa, J.-C.and Plumas, J. Leukemic plasmacytoiddendritic cells share phenotypic and func-tional features with their normal counter-parts . . . . . . . . . . . . . . . . . . . . . . . . . 418

Chapgier, A., see Feinberg, J.Chapuis, B., see Arlettaz, L.Chau, L. A., see Bueno, C.Chauffert, B., see Ghiringhelli, F.Chemin, K., see Chapat, L.Chemin, K., see Eyquem, S.Chen, A., see Wang, L.Chen, C.-A., see Cheng, W.-F.Chen, J., Vistica, B. P., Takase, H., Ham, D.

I., Fariss, R. N., Wawrousek, E. F., Chan,C.-C., DeMartino, J. A., Farber, J. M.and Gery, I. A unique pattern of up- anddown-regulation of chemokine receptorCXCR3 on inflammation-inducing Th1cells . . . . . . . . . . . . . . . . . . . . . . . . . 2885

Chen, L. and Jondal, M. Alternative pro-cessing for MHC class I presentation byimmature and CpG-activated dendriticcells . . . . . . . . . . . . . . . . . . . . . . . . . . 952

Chen, W., Masterman, K.-A., Basta, S.,Mansour Haeryfar, S. M., Dimopoulos,N., Knowles, B., Bennink, J. R. and Yew-dell, J. W. Cross-priming of CD8+ T cellsby viral and tumor antigens is a robustphenomenon . . . . . . . . . . . . . . . . . . . 194

Chen, X., Murakami, T., Oppenheim, J. J.and Howard, O. M. Z. Differentialresponse of murine CD4+CD25+ andCD4+CD25– T cells to dexamethasone-induced cell death . . . . . . . . . . . . . . . 859

Cheng, W.-F., Hung, C.-F., Lee, C.-N., Su,Y.-N., Chang, M.-C., He, L., Wu, T.-C.,Chen, C.-A. and Hsieh, C.-Y. Naked RNAvaccine controls tumors with down-

VI Author Index

regulated MHC class I expression throughNK cells and perforin-dependent path-ways . . . . . . . . . . . . . . . . . . . . . . . . 1892

Chhabra, A., Mehrotra, S., Chakraborty, N.G., Mukherji, B. and Dorsky, D. I. Cross-presentation of a human tumor antigendelivered to dendritic cells by HSV VP22-mediated protein translocation . . . . 2824

Chiesa, M. D., see Vitale, M.Chilla, S., see Luckow, B.Chilvers, E. R., see Cowburn, A. S.Chin, R. K., see Lian, R. H.Chiossone, L., see Vitale, C.Cho, M.-S., see Lemaıtre, F.Choi, I.-W., see Seo, K. H.Choi, J. H., see Seo, K. H.Chopin, M., see Eyquem, S.Chowdhary, B. P., see Takahashi, T.Christensen, J. E., Wodarz, D., Christen-

sen, J. P. and Thomsen, A. R. Perforinand IFN- + do not significantly regulate thevirus-specific CD8+ T cell response in theabsence of antiviral effector activity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1389

Christensen, J. P., see Christensen, J. E.Christoph, H., see Mautner, J.Chun, T., see Yang, J.-Q.Chun, Y. H., see Seo, K. H.Chung, Y., Chang, W.-S., Kim, S. and

Kang, C.-Y. NKT cell ligand § -galactosylceramide blocks the inductionof oral tolerance by triggering dendriticcell maturation. . . . . . . . . . . . . . . . . 2471

Ciurana, C. L. F., Zwart, B., van Mierlo, G.and Hack, C. E. Complement activationby necrotic cells in normal plasma envi-ronment compares to that by late apop-totic cells and involves predominantly IgM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2609

Cividini, A., see Accapezzato, D.Cividini, A., see Francavilla, V.Claesson, M. H., see Gad, M.Clahsen, T., see Weissenbach, M.Clark, S. L., see Alard, P.Clarke, K., see Okamoto, S.Cleary, P. P., see Park, H.-S.Clouston, A. D., see Ward, S. M.Coccia, E. M., Severa, M., Giacomini, E.,

Monneron, D., Remoli, M. E., Julkunen,I., Cella, M., Lande, R. and Uze, G. Viralinfection and Toll-like receptor agonistsinduce a differential expression of type Iand Q interferons in human plasmacytoidand monocyte-derived dendritic cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 796

Cogne, M., see Glaudet, F.Cohen, C. J., see Held, G.Cohen, C. J., see Zehn, D.Cohen, I. R., see Herkel, J.Cohen, N., see Goyos, A.Colantonio, L., Rossi, B., Constantin, G.

and D’Ambrosio, D. Integration and inde-pendent acquisition of specialized skin-versus gut-homing and Th1 versus Th2cytokine synthesis phenotypes in humanCD4+ T cells. . . . . . . . . . . . . . . . . . . 2419

Collette, Y., see Compte, E.

Colombatto, P., see Masciopinto, F.Colotta, F., see Martinez, F. O.Colucci, F., see Bell, S. E.Comalada, M., Xaus, J., Sanchez, E., Val-

ledor, A. F. and Celada, A. Macrophagecolony-stimulating factor-, granulo-cyte-macrophage colony-stimulatingfactor-, or IL-3-dependent survival ofmacrophages, but not proliferation,requires the expression of p21Waf1 throughthe phosphatidylinositol 3-kinase/Aktpathway . . . . . . . . . . . . . . . . . . . . . . 2257

Combadiere, B., see Boissonnas, A.Compte, E., Pontarotti, P., Collette, Y.,

Lopez, M. and Olive, D. Frontline: Char-acterization of BT3 molecules belongingto the B7 family expressed on immunecells . . . . . . . . . . . . . . . . . . . . . . . . . 2089

Connolly, G., see Green, K. J.Constantin, G., see Colantonio, L.Contemi, A. M., see Rutella, S.Conway, H., see Andre, P.Cook, H. T., see Cortes-Hernandez, J.Cooke, A., see Zaccone, P.Corcoran, A. E., see Erlandsson, L.Cortes-Hernandez, J., Fossati-Jimack, L.,

Petry, F., Loos, M., Izui, S., Walport, M.J., Cook, H. T. and Botto, M. Restorationof C1q levels by bone marrow transplan-tation attenuates autoimmune diseaseassociated with C1q deficiency inmice. . . . . . . . . . . . . . . . . . . . . . . . . 3713

Cosimi, O., see Francavilla, V.Coso, O. A., see Stempin, C. C.Costa, P., see Fogli, M.Costalonga, M., see Park, H.-S.Costello, R. T., see Duhen, T.Cotta-de-Almeida, V., Villa-Verde, D. M. S.,

Lepault, F., Pleau, J.-M., Dardenne, M.and Savino, W. Impaired migration ofNOD mouse thymocytes: a fibronectinreceptor-related defect . . . . . . . . . . 1578

Cottalasso, F., see Vitale, C.Coutant, F., see Perrin-Cocon, L.Couvreur, P., see de Kozak, Y.Cowburn, A. S., Deighton, J., Walmsley, S.

R. and Chilvers, E. R. The survival effectof TNF- § in human neutrophils is me-diated via NF- ‹ B-dependent IL-8 re-lease . . . . . . . . . . . . . . . . . . . . . . . . 1733

Coyle, A. J., see Okamoto, S.Coyle, A. J., see Scales, H. E.Coyle, A. J., see Vieira, P. L.Creput, C., see Le Rond, S.Creutzburg, F., see Hallatschek, W.Crocker, P. R., see Zhang, J. Q.Croft, M., see Pakala, S. V.Cross, R., see Nance, S.Crough, T., see Elkington, R.Cuadros, C., see Lustgarten, J.Cumano, A., see Eyquem, S.Cunningham, A. F., Serre, K., Toellner, K.-

M., Khan, M., Alexander, J., Bromba-cher, F. and MacLennan, I. C. M. Pin-pointing IL-4-independent acquisition andIL-4-influenced maintenance of Th2 activ-ity by CD4 T cells . . . . . . . . . . . . . . . 686

Cunningham, A. F., Khan, M., Ball, J., Toel-lner, K.-M., Serre, K., Mohr, E. and Mac-Lennan, I. C. M. Responses to the solubleflagellar protein FliC are Th2, while thoseto FliC on Salmonella are Th1 . . . . . 2986

Curiel, T., see Pulendran, B.Curti, A., see Rutella, S.da Costa, C. U. P., Wantia, N., Kirschning,

C. J., Busch, D. H., Rodriguez, N., Wag-ner, H. and Miethke, T. Heat shock pro-tein 60 from Chlamydia pneumoniae elicitsan unusual set of inflammatory responsesvia Toll-like receptor 2 and 4 in vivo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2874

Daga, A., see Oliveri, M.Dagan, M., see Franitza, S.Dagan-Berger, M., see Wald, O.Daha, M. R., see Roos, A.Dai, K.-Z., see Helgeland, L.D’Ambrosio, D., see Colantonio, L.D’Ambrosio, D., see Mariani, M.Dammacco, F., see Sansonno, D.Daniel, C., see Baratin, M.Dao, T., Guo, D., Ploss, A., Stolzer, A., Say-

lor, C., Boursalian, T. E., Im, J. S. andSant’Angelo, D. B. Development ofCD1d-restricted NKT cells in the mousethymus. . . . . . . . . . . . . . . . . . . . . . . 3542

Darash-Yahana, M., see Franitza, S.Dardenne, M., see Cotta-de-Almeida, V.Dardenne, M., see Geutskens, S. B.Das, S., see Alli, R.Dausset, J., see Le Rond, S.David, C., see Mangalam, A. K.Davidson, A., see Ye, Q.Davis, H. L., see Vollmer, J.Davison, J., see Dery, R. E.Dawicki, W. and Watts, T. H. Expression

and function of 4-1BB during CD4 versusCD8 T cell responses in vivo . . . . . . . 743

de Beaucoudrey, L., see Feinberg, J.de Boer, M., see de Vos, A. F.de Chasseval, R., see Poinsignon, C.de Guibert, S., see Birebent, B.de Heredia, A. B., see Caparros, E.de Heusch, M., Oldenhove, G., Urbain, J.,

Thielemans, K., Maliszewski, C., Leo, O.and Moser, M. Depending on their matu-ration state, splenic dendritic cells inducethe differentiation of CD4+ T lymphocytesinto memory and/or effector cells in vivo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1861

de Jong, D. J., see Netea, M. G.de Jong, E., see Smits, H. H.de Kozak, Y., Andrieux, K., Villarroya, H.,

Klein, C., Thillaye-Goldenberg, B.,Naud, M.-C., Garcia, E. and Couvreur, P.Intraocular injection of tamoxifen-loadednanoparticles: a new treatment of experi-mental autoimmune uveoretinitis . . 3702

de la Rosa, G., see Riol-Blanco, L.de la Rosa, M., Rutz, S., Dorninger, H. and

Scheffold, A. Interleukin-2 is essential forCD4+CD25+ regulatory T cell function. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2480

de Lema, G. P., see Luckow, B.De Maria, A., see Fogli, M.

Author Index VII

De Maria, R., see Eramo, A.De Re, V., see Sansonno, D.de Rham, C., see Arlettaz, L.de Ritis, D. G., see Rutella, S.de Ru, A. H., see Verdijk, P.De Salvo, M., see Francavilla, V.de Villartay, J.-P., see Poinsignon, C.de Vos, A. F., Melief, M.-J., van Riel, D.,

Boon, L., van Eijk, M., de Boer, M. andLaman, J. D. Antagonist anti-humanCD40 antibody inhibits germinal centerformation in cynomolgus monkeys. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3446

de Vries, J. E., see Beinhauer, B. G.Deai, K., see Tanaka, S.Dean, M., see Shakhov, A. N.Debes, G. F., see Kretschmer, U.Debre, P., see Dogan, I.Dechanet-Merville, J., see Pascal, V.Decker, P., see Dengjel, J.Degermann, S., see Arlettaz, L.Deighton, J., see Cowburn, A. S.Dejean, A. S., see Xystrakis, E.DeMartino, J. A., see Chen, J.Deneys, V., see Chaperot, L.Deng, H.-X., see Tan, G.-H.Dengjel, J., Decker, P., Schoor, O., Alten-

berend, F., Weinschenk, T., Rammen-see, H.-G. and Stevanovic, S. Identifica-tion of a naturally processed cyclin D1 T-helper epitope by a novel combination ofHLA class II targeting and differentialmass spectrometry . . . . . . . . . . . . . 3644

Denis, V., see Glaudet, F.Derks, I. A. M., see Eldering, E.Dery, R. E., Ulanova, M., Puttagunta, L.,

Stenton, G. R., James, D., Merani, S.,Mathison, R., Davison, J. and Befus, A.D. Frontline: Inhibition of allergen-inducedpulmonary inflammation by the tripeptidefeG: a mimetic of a neuro-endocrine path-way . . . . . . . . . . . . . . . . . . . . . . . . . 3315

Deschamps, M., see Le Rond, S.Desgranges, C., see Partidos, C. D.DeSimone, D. C., see Feuerstein, N.Dieli, F., see Caccamo, N.Dieli, F., see Farouk, S. E.Dieli, F., Caccamo, N., Meraviglia, S., Iva-

nyi, J., Sireci, G., Bonanno, C. T., Fer-lazzo, V., Mendola, C. L. and Salerno, A.Reciprocal stimulation of + ˇ T cells anddendritic cells during the antimyco-bacterial immune response . . . . . . . 3227

Diem, S., see Araujo, L. M.Dierkes, S., see Layland, L. E.Dighiero, G., see Oppezzo, P.Dignat-George, F., see Pascal, V.Dikopoulos, N., see Jomantaite, I.Dillon, S., see Pulendran, B.Dimopoulos, N., see Chen, W.Dinarello, C. A., see Siegmund, B.Ding, Z.-Y., see Tan, G.-H.Dini, G., see Vitale, C.Dissen, E., see Storset, A. K.Dissen, E., see Helgeland, L.Dittmer, J., see Probst, J.Döcke, W.-D., see Jung, M.

Doffinger, R., see Feinberg, J.Dogan, I., Dorgham, K., Chang, H.-C., Pari-

zot, C., Lemaıtre, F., Ferradini, L., Rein-herz, E. L., Debre, P. and Gorochov, G.Phage-displayed libraries of peptide/majorhistocompatibility complexes . . . . . . . 598

Doherty, D. G., see O’Keeffe, J.Dombek, P. E., see Park, H.-S.Dominguez, A. L., see Lustgarten, J.Donahue, A. C., see Hess, K. L.Dondero, A., see Andre, P.Dong, T., see Hansasuta, P.Dorgham, K., see Dogan, I.Dorninger, H., see de la Rosa, M.Dorsky, D. I., see Chhabra, A.Draber, P., see Tolar, P.Draber, P., see Tolarova, H.Draber, P., see Draberova, L.Draberova, L., see Tolar, P.Draberova, L., see Tolarova, H.Draberova, L., Lebduska, P., Halova, I.,

Tolar, P., Stokrova, J., Tolarova, H.,Korb, J. and Draber, P. Signaling assem-blies formed in mast cells activated viaFc 4 receptor I dimers. . . . . . . . . . . . 2209

Dransfield, I., see Heasman, S. J.Drenth, J. P. H., see Netea, M. G.Droese, J., see Höpken, U. E.Droin, N., see Altman, A.Druet, P., see Xystrakis, E.D’Sa, A., see Swirski, F. K.D’Souza, W. N. and Lefrancois, L. Frontline:

An in-depth evaluation of the productionof IL-2 by antigen-specific CD8 T cells invivo . . . . . . . . . . . . . . . . . . . . . . . . . 2977

Dubois, B., see Chapat, L.Dudda, J., see Averbeck, M.Duhen, T., Pasero, C., Mallet, F., Barbarat,

B., Olive, D. and Costello, R. T. LIGHTcostimulates CD40 triggering and inducesimmunoglobulin secretion; a novel keypartner in T cell-dependent B cell terminaldifferentiation. . . . . . . . . . . . . . . . . . 3534

Dukers, D. F., see van Galen, J. C.Dumas, G., see Oppezzo, P.Dumler, J. S., see von Loewenich, F. D.Duperrier, K., see Velten, F. W.Durrbach, A., see Le Rond, S.Dusheiko, G., see Barnes, E.Dy, M., see Araujo, L. M.Dy, M., see Lisbonne, M.Eason, D. D., Litman, R. T., Luer, C. A.,

Kerr, W. and Litman, G. W. Expression ofindividual immunoglobulin genes occursin an unusual system consisting of multi-ple independent loci . . . . . . . . . . . . 2551

Ebensen, T., see Link, C.Ebert, L. M., Horn, M. P., Lang, A. B. and

Moser, B. B cells alter the phenotype andfunction of follicular-homing CXCR5+ Tcells . . . . . . . . . . . . . . . . . . . . . . . . . 3562

Ebling, F. M., see Karpouzas, G. A.Eggert, A. O., Andersen, M. H., Voigt, H.,

Schrama, D., Kämpgen, E., Straten, P. t.and Becker, J. C. Characterization ofmouse MAGE-derived H-2Kb-restrictedCTL epitopes . . . . . . . . . . . . . . . . . . 3285

Ehl, S., Bischoff, R., Ostler, T., Vallbracht,S., Schulte-Mönting, J., Poltorak, A.and Freudenberg, M. The role of Toll-likereceptor 4 versus interleukin-12 in immu-nity to respiratory syncytial virus. . . 1146

Ehlers, S. Commentary: Adaptive immunityin the absence of innate immuneresponses? The un-Tolled truth of thesilent invaders . . . . . . . . . . . . . . . . . 1783

Ehrnfelt, C., see He, Z.Ehtesham, M., see Liu, G.Eichmann, K., see Nil, A.Eid, A., see Wald, O.Eing, B. R., see Loser, K.Eisenberg, R. A., see Feuerstein, N.Eisenstein, M., see Herkel, J.Eizirik, D. L., see Vermijlen, D.Eldering, E., Mackus, W. J. M., Derks, I. A.

M., Evers, L. M., Beuling, E., Teeling, P.,Lens, S. M. A., van Oers, M. H. J. andvan Lier, R. A. W. Apoptosis via the B cellantigen receptor requires Bax transloca-tion and involves mitochondrial depolar-ization, cytochrome C release, andcaspase-9 activation . . . . . . . . . . . . 1950

Elkington, R., Shoukry, N. H., Walker, S.,Crough, T., Fazou, C., Kaur, A., Walker,C. M. and Khanna, R. Cross-reactiverecognition of human and primate cyto-megalovirus sequences by human CD4cytotoxic T lymphocytes specific for gly-coprotein B and H . . . . . . . . . . . . . . 3216

Elliott, D. E., Setiawan, T., Metwali, A.,Blum, A., Urban, J. F. and Weinstock, J.V. Heligmosomoides polygyrus inhibitsestablished colitis in IL-10-deficientmice. . . . . . . . . . . . . . . . . . . . . . . . . 2690

Ellmerich, S., Takacs, K., Mycko, M., Wald-ner, H., Wahid, F., Boyton, R. J., Smith,P. A., Amor, S., Baker, D., Hafler, D. A.,Kuchroo, V. K. and Altmann, D. M.Disease-related epitope spread in ahumanized T cell receptor transgenicmodel of multiple sclerosis . . . . . . . 1839

Endert, P. V., see Gil-Torregrosa, B. C.Engelhardt, B. and Wolburg, H. Mini-

review: Transendothelial migration of leu-kocytes: through the front door or aroundthe side of the house?. . . . . . . . . . . 2955

Enk, A. H., see Stassen, M.Enserink, J., see Vang, T.Epel, M., see Held, G.Eramo, A., Sargiacomo, M., Ricci-Vitiani,

L., Todaro, M., Stassi, G., Messina, C. G.M., Parolini, I., Lotti, F., Sette, G.,Peschle, C. and De Maria, R. CD95death-inducing signaling complex forma-tion and internalization occur in lipid raftsof type I and type II cells . . . . . . . . . 1930

Erb, K. J., see Kretschmer, U.Erez, N., see Herkel, J.Ericsson, A., see Stenström, M.Ericsson, A., Svensson, M., Arya, A. and

Agace, W. W. CCL25/CCR9 promotesthe induction and function of CD103 onintestinal intraepithelial lymphocytes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2720

VIII Author Index

Eriksson, K., Sun, J.-B., Nordström, I.,Fredriksson, M., Lindblad, M., Li, B.-L.and Holmgren, J. Coupling of antigen tocholera toxin for dendritic cell vaccinationpromotes the induction of MHC class I-restricted cytotoxic T cells and the rejec-tion of a cognate antigen-expressingmodel tumor . . . . . . . . . . . . . . . . . . 1272

Erl, W., Weber, C., Zernecke, A., Neuzil, J.,Vosseler, C. A., Kim, H. J. and Weber, P.C. Cyclopentenone prostaglandins induceendothelial cell apoptosis independent ofthe peroxisome proliferator-activatedreceptor- + . . . . . . . . . . . . . . . . . . . . . 241

Erlandsson, L., Licence, S., Gaspal, F.,Bell, S., Lane, P., Corcoran, A. E. andMårtensson, I.-L. Impaired B-1 and B-2B cell development and atypical splenic Bcell structures in IL-7 receptor-deficientmice. . . . . . . . . . . . . . . . . . . . . . . . . 3595

Espeli, M., see Andre, P.Evavold, B. D., see Ford, M. L.Evers, L. M., see Eldering, E.Eyquem, S., Chemin, K., Fasseu, M., Cho-

pin, M., Sigaux, F., Cumano, A. andBories, J.-C. The development of earlyand mature B cells is impaired in micedeficient for the Ets-1 transcription factor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3187

Faber-Krol, M. C., see Roos, A.Fahlen, S., see Hietala, M. A.Falco, M., Marcenaro, E., Romeo, E., Bel-

lora, F., Marras, D., Vely, F., Ferracci, G.,Moretta, L., Moretta, A. and Bottino, C.Homophilic interaction of NTBA, a mem-ber of the CD2 molecular family: inductionof cytotoxicity and cytokine release inhuman NK cells . . . . . . . . . . . . . . . . 1663

Fan, Y., see Bilenki, L.Fan, Y., see Han, X.Fantuzzi, G., see Siegmund, B.Farber, J. M., see Chen, J.Farfan, N., see Baeza, I.Fariss, R. N., see Chen, J.Farouk, S. E., Mincheva-Nilsson, L.,

Krensky, A. M., Dieli, F. and Troye-Blomberg, M. + ˇ T cells inhibit in vitrogrowth of the asexual blood stages ofPlasmodium falciparum by a granuleexocytosis-dependent cytotoxic pathwaythat requires granulysin . . . . . . . . . . 2248

Farrar, J. D., see Berenson, L. S.Fasseu, M., see Eyquem, S.Favier, A., see Preynat-Seauve, O.Favrot, M.-C., see Preynat-Seauve, O.Fazilleau, N., see Pajot, A.Fazou, C., see Elkington, R.Fedele, G., Frasca, L., Palazzo, R., Ferrero,

E., Malavasi, F. and Ausiello, C. M. CD38is expressed on human mature monocyte-derived dendritic cells and is functionallyinvolved in CD83 expression and IL-12induction . . . . . . . . . . . . . . . . . . . . . 1342

Feinberg, J., Fieschi, C., Doffinger, R.,Feinberg, M., Leclerc, T., Boisson-Dupuis, S., Picard, C., Bustamante, J.,Chapgier, A., Filipe-Santos, O., Ku, C.-

L., de Beaucoudrey, L., Reichenbach,J., Antoni, G., Balde, R., Alcaıs, A. andCasanova, J.-L. Bacillus Calmette Guerintriggers the IL-12/IFN- + axis by an IRAK-4- and NEMO-dependent, non-cognateinteraction between monocytes, NK, andT lymphocytes . . . . . . . . . . . . . . . . . 3276

Feinberg, M., see Feinberg, J.Feito, M. J., see Sanchez, A.Feldhahn, N., see Su, Y.-w.Ferlazzo, V., see Dieli, F.Ferlin, W. G., Mougneau, E., Hugues, S.,

Appel, H., Jang, M.-H., Cazareth, J.,Beaudoin, L., Schricke, C., Lehuen, A.,Wucherpfennig, K. W. and Glaichen-haus, N. Frontline: Self-peptides that bindwith low affinity to the diabetes-associated I-Ag7 molecule readily induce Tcell tolerance in non-obese diabetic mice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2656

Fernandez-Ruiz, E., see Arce, I.Fernekorn, U., Butcher, E. C., Behrends,

J., Hartz, S. and Kruse, A. Functionalinvolvement of P-selectin and MAdCAM-1in the recruitment of § 4 g 7-integrin-expressing monocyte-like cells to thepregnant mouse uterus . . . . . . . . . . 3423

Ferracci, G., see Falco, M.Ferradini, L., see Dogan, I.Ferradini, L., see Lemaıtre, F.Ferrari, C., see Missale, G.Ferrero, E., see Fedele, G.Fest, S., see Zenclussen, A. C.Fesüs, L., see Toth, B.Feterowski, C., Mack, M., Weighardt, H.,

Bartsch, B., Kaiser-Moore, S. and Holz-mann, B. CC chemokine receptor 2 regu-lates leukocyte recruitment and IL-10 pro-duction during acute polymicrobial sepsis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3664

Feuerstein, N., DeSimone, D. C., Eisen-berg, R. A. and Finkel, T. H. Chronicgraft-versus-host reaction is associatedwith a decrease in Ig light chain receptorediting in bone marrow self-reactive Bcells . . . . . . . . . . . . . . . . . . . . . . . . . 1361

Fiedler, G., see Hallatschek, W.Fieschi, C., see Feinberg, J.Filipe-Santos, O., see Feinberg, J.Finkel, T. H., see Feuerstein, N.Finkelman, F. D., see Han, S.Finotto, S., see Hausding, M.Firat, E., see Nil, A.Fischer, A., see Poinsignon, C.Fischer, A., see Trucy, M.Fishelson, Z., see Attali, G.Fisher, A. G., see Hewitt, S. L.Fitzpatrick, D. R., see Oflazoglu, E.Fitzpatrick, E., see Nance, S.Flaishon, L., see Topilski, I.Fleischer, B., see Jacobs, T.Fleming, H. E., see Milne, C. D.Flores, J. M., see Carvalho-Pinto, C.Flores-Romo, L., see Baeza, I.Fogli, M., Costa, P., Murdaca, G., Setti, M.,

Mingari, M. C., Moretta, L., Moretta, A.and De Maria, A. Significant NK cell acti-

vation associated with decreased cyto-lytic function in peripheral blood of HIV-1-infected patients . . . . . . . . . . . . . . . 2313

Fondel, S., see Stassen, M.Fontana, A., see LeibundGut-Landmann,

S.Ford, M. L. and Evavold, B. D. An MHC

anchor-substituted analog of myelin oligo-dendrocyte glycoprotein 35–55 inducesIFN- + and autoantibodies in the absenceof experimental autoimmune encephalo-myelitis and optic neuritis . . . . . . . . . 388

Ford, N. J., see Ludewig, B.Förster, I., see Vossenkämper, A.Fossati-Jimack, L., see Cortes-Hernandez,

J.Fossati-Jimack, L., see Kuroki, A.Fourneau, J.-M., see Lemaıtre, F.Fourneau, J.-M., see Lisbonne, M.Fowke, K. R., see Mayne, M.Francavilla, V., see Accapezzato, D.Francavilla, V., Accapezzato, D., De Salvo,

M., Rawson, P., Cosimi, O., Lipp, M.,Cerino, A., Cividini, A., Mondelli, M. U.and Barnaba, V. Subversion of effectorCD8+ T cell differentiation in acute hepati-tis C virus infection: exploring the immu-nological mechanisms. . . . . . . . . . . . 427

Franitza, S., see Wald, O.Franitza, S., Grabovsky, V., Wald, O.,

Weiss, I., Beider, K., Dagan, M., Darash-Yahana, M., Nagler, A., Brocke, S.,Galun, E., Alon, R. and Peled, A. Differ-ential usage of VLA-4 and CXCR4 byCD3+CD56+ NKT cells and CD56+CD16+

NK cells regulates their interaction withendothelial cells. . . . . . . . . . . . . . . . 1333

Franke, B., see Netea, M. G.Frasca, L., see Fedele, G.Fredriksson, M., see Eriksson, K.Fresno, M., see Alcaide, P.Freudenberg, M., see Ehl, S.Friedman, R. S., Spies, A. G. and Kalos, M.

Identification of naturally processed CD8T cell epitopes from prostein, a prostatetissue-specific vaccine candidate . . 1091

Friedrich, M., see Jung, M.Fruci, D., see Gil-Torregrosa, B. C.Fruman, D. A., see Hess, K. L.Fu, C.-H., see Tan, G.-H.Fu, Y.-X., see Lian, R. H.Fugger, L., see Rich, C.Fugmann, S. D., Rush, J. S. and Schatz, D.

G. Non-redundancy of cytidine deami-nases in class switch recombination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 844

Fujita, T., see Roos, A.Fujiwara, M., see Ueno, T.Funabashi, H., see Takedatsu, H.Gad, M., Pedersen, A. E., Kristensen, N. N.

and Claesson, M. H. Demonstration ofstrong enterobacterial reactivity ofCD4+CD25– T cells from conventional andgerm-free mice which is counter-regulated by CD4+CD25+ T cells . . . . 695

Gadella, B. M., see Nolte-‘t Hoen, E. N. M.Gajewska, B. U., see Swirski, F. K.

Author Index IX

Galle, P., Hougs, L., Barington, T., Sven-son, M., Svejgaard, A., Thomsen, A. R.,Bendtzen, K. and Hansen, M. B. Knock-ing out IL-6 by vaccination . . . . . . . . 291

Galle, P., Svenson, M., Bendtzen, K. andHansen, M. B. High levels of neutralizingIL-6 autoantibodies in 0.1% of apparentlyhealthy blood donors . . . . . . . . . . . 3267

Galle, P. R., see Hausding, M.Galli-Stampino, L., see Masciopinto, F.Galun, E., see Franitza, S.Galun, E., see Wald, O.Gancz, D., see Attali, G.Ganss, R., Arnold, B. and Hämmerling, G.

J. Mini-review: Overcoming tumor-intrinsic resistance to immune effectorfunction . . . . . . . . . . . . . . . . . . . . . . 2635

Gantress, J., see Goyos, A.Garcia, E., see de Kozak, Y.Garcıa, M. I., see Carvalho-Pinto, C.Garcıa-Bordas, J., see Riol-Blanco, L.Garcon, F., Ghiotto, M., Gerard, A., Yang,

W.-C., Olive, D. and Nunes, J. A. TheSH3 domain of Tec kinase is essential forits targeting to activated CD28 costimula-tory molecule. . . . . . . . . . . . . . . . . . 1972

Garred, P., see Roos, A.Garrido, C., see Ghiringhelli, F.Garside, P., see Scales, H. E.Gaspal, F., see Erlandsson, L.Gatti, P., see Sansonno, D.Gavioli, R., see Link, C.Gaworski, I., see Jacobs, T.Gazit, R., Rechnitzer, H., Achdout, H., Kat-

zenell, A., Katz, G., Markel, G., Arnon, T.I., Gonen-Gross, T., Mizrahi, S., Gruda,R., Rottem, S. and Mandelboim, O. Rec-ognition of Mycoplasma hyorhinis byCD99-Fc molecule. . . . . . . . . . . . . . 2032

Gazit, R., see Markel, G.Gebe, J. A., Masewicz, S. A., Kochik, S. A.,

Reijonen, H. and Nepom, G. T. Inhibitionof altered peptide ligand-mediated antag-onism of human GAD65-responsive CD4+

T cells by non-antagonizable T cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3337

Geboes, K., see Gijsbers, K.Geffers, R., see Bruder, D.Geisel, W., see Holtmeier, W.Gellert, T., see Rutz, M.Genain, C. P., see von Büdingen, H.-C.Geng, M., see Wang, L.George, A. J. T., see Arancibia-Carcamo,

C. V.Gerard, A., see Garcon, F.Gergely, J., see Medgyesi, D.Gerhold, K., see Stock, P.Gerth, A. J., see Lin, L.Gery, I., see Chen, J.Geutskens, S. B., Nikolic, T., Dardenne,

M., Leenen, P. J. M. and Savino, W.Defective up-regulation of CD49d in finalmaturation of NOD mouse macrophages. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3465

Ghiotto, M., see Garcon, F.Ghiringhelli, F., Larmonier, N., Schmitt, E.,

Parcellier, A., Cathelin, D., Garrido, C.,

Chauffert, B., Solary, E., Bonnotte, B.and Martin, F. CD4+CD25+ regulatory Tcells suppress tumor immunity but aresensitive to cyclophosphamide whichallows immunotherapy of establishedtumors to be curative . . . . . . . . . . . . 336

Giacomini, E., see Coccia, E. M.Giaisi, M., see Li-Weber, M.Giese, T., see Müller, D. B.Gijsbers, K., Van Assche, G., Joossens, S.,

Struyf, S., Proost, P., Rutgeerts, P.,Geboes, K. and Van Damme, J. CXCR1-binding chemokines in inflammatorybowel diseases: down-regulated IL-8/CXCL8 production by leukocytes inCrohn’s disease and selective GCP-2/CXCL6 expression in inflamed intestinaltissue . . . . . . . . . . . . . . . . . . . . . . . . 1992

Giles, K. M., see Heasman, S. J.Gil-Gomez, G., see Granes, F.Gil-Torregrosa, B. C., Lennon-Dumenil, A.

M., Kessler, B., Guermonprez, P., Ploegh,H. L., Fruci, D., Endert, P. V. and Amigo-rena, S. Control of cross-presentation dur-ing dendritic cell maturation . . . . . . . . 398

Giovani, C., see Masciopinto, F.Girardin, S. E. and Philpott, D. J. Mini-

review: The role of peptidoglycan recogni-tion in innate immunity . . . . . . . . . . 1777

Giroth, C., see van Galen, J. C.Gladow, M., Uckert, W. and Blankenstein,

T. Dual T cell receptor T cells with twodefined specificities mediate tumor sup-pression via both receptors. . . . . . . 1882

Glaichenhaus, N., see Ferlin, W. G.Glaichenhaus, N., see Lauvau, G.Glanzmann, B., see Vollstedt, S.Glaudet, F., Denis, V., Cogne, M. and

Khamlichi, A. A. Induction of somatichypermutation by antigen-specific B cellreceptors in the human BL2 cell line. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1637

Gleichmann, E., see Layland, L. E.Gnjatic, S., see Held, G.Goerdt, S., see Velten, F. W.Goji, H., see Shimamura, M.Goldman, M., see Verhasselt, V.Golshayan, D. and Lechler, R. Commen-

tary: Priming of alloreactive T cells – wheredoes it happen?. . . . . . . . . . . . . . . . 3301

Gomez, L., see Carvalho-Pinto, C.Gomez-Bougie, P., Bataille, R. and Amiot,

M. The imbalance between Bim and Mcl-1expression controls the survival of humanmyeloma cells . . . . . . . . . . . . . . . . . 3156

Gonen-Gross, T., see Gazit, R.Gonen-Gross, T., see Markel, G.Gopinathan, L., see Pishko, E. J.Gordon, S., see Marshall, A. S. J.Gorgone, D. A., see McKay, P. F.Gorochov, G., see Dogan, I.Götze, O., see Schlaf, G.Goyos, A., Cohen, N., Gantress, J. and

Robert, J. Anti-tumor MHC class Ia-unrestricted CD8 T cell cytotoxicity elic-ited by the heat shock protein gp96. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2449

Grabovsky, V., see Franitza, S.Graf, P., see Beinhauer, B. G.Granes, F., Roig, M. B., Brady, H. J. M. and

Gil-Gomez, G. Cdk2 activation actsupstream of the mitochondrion during glu-cocorticoid induced thymocyte apoptosis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2781

Gras-Masse, H., see Zhu, X.Green, K. J., Miles, J. J., Tellam, J., van

Zuylen, W. J. M., Connolly, G. and Bur-rows, S. R. Potent T cell response to aclass I-binding 13-mer viral epitope andthe influence of HLA micropolymorphismin controlling epitope length . . . . . . 2510

Greer, F., see Hensmann, M.Greiner, E., see Baumann, S.Grencis, R. K., see Helmby, H.Greve, B., Reddy, J., Waldner, H.-P., Sobel,

R. A. and Kuchroo, V. K. Dissimilar back-ground genes control susceptibility toautoimmune disease in the context of dif-ferent MHC haplotypes: NOD.H-2s con-genic mice are relatively resistant to bothexperimental autoimmune encephalo-myelitis and type I diabetes . . . . . . 1828

Griesemer, D., see Tutsch, E.Grill, S. M., see Oswald-Richter, K.Gröne, H.-J., see Luckow, B.Grosfeld-Stulemeyer, M. C., see Nolte-‘t

Hoen, E. N. M.Groth, D. M., see Urwin, D. L.Gruda, R., see Gazit, R.Gruda, R., see Markel, G.Grütz, G., see Jung, M.Guermonprez, P., see Gil-Torregrosa,

B. C.Guilbault, B., see Klinger, M. B.Gullo, C., see Okamoto, S.Günder, M., see Hofmann, M.Guo, D., see Dao, T.Gutches, D. G., see Wheat, W.Gutierrez-Ramos, J. C., see Vieira, P. L.Gutierrez-Ramos, J.-C., see Scales, H. E.Guzman, C. A., see Link, C.Hache, R. J. G., see Poinsignon, C.Hachem, P., see Lisbonne, M.Hachimura, S., see Kuraoka, M.Hack, C. E., see Ciurana, C. L. F.Häcker, G., see Chaneva, S.Häcker, G., see Kirschnek, S.Hafler, D. A., see Ellmerich, S.Hahn, B. H., see Karpouzas, G. A.Hakulinen, J., Junnikkala, S., Sorsa, T. and

Meri, S. Complement inhibitor membranecofactor protein (MCP; CD46) is constitu-tively shed from cancer cell membranesin vesicles and converted by a metallo-proteinase to a functionally active solubleform . . . . . . . . . . . . . . . . . . . . . . . . . 2620

Hall, H. T. L., Petrovic, J. and Höglund, P.Reduced antigen concentration andcostimulatory blockade increase IFN- +secretion in naive CD8+ T cells . . . . 3091

Hallatschek, W., Fiedler, G., Kirschning, C.J., Creutzburg, F., Lamping, N., Nüssler,A. and Schumann, R. R. Inhibition ofhepatic transcriptional induction of lipo-

X Author Index

polysaccharide-binding protein by trans-forming-growth-factor g 1 . . . . . . . . 1441

Halova, I., see Draberova, L.Halteman, B. S., see Pakala, S. V.Ham, D. I., see Chen, J.Hamann, A., see Kretschmer, U.Hamelmann, E., see Stock, P.Hämmerling, G. J., see Ganss, R.Hammerschmidt, W., see Mautner, J.Han, R., see Ye, Q.Han, S., Zhang, X., Xu, R., Finkelman, F. D.,

Brombacher, F. and Zheng, B. IgD+IgM–

B cells mount immune responses thatexhibit altered antibody repertoire . . 661

Han, X., Fan, Y., Wang, S., Yang, J., Bilenki,L., Qiu, H., Jiao, L. and Yang, X. Dendriticcells from Chlamydia-infected mice showaltered Toll-like receptor expression andplay a crucial role in inhibition of allergicresponses to ovalbumin . . . . . . . . . . 981

Han, Y. H., see Moon, E.-Y.Han, Y.-M., see Moon, E.-Y.Hanayama, R., see Miyasaka, K.Hancock, W. W., see Ye, Q.Handa, K., see Takedatsu, H.Hanna, J., see Markel, G.Hanna, J., see Wald, O.Hanrahan, S., see Laurence, A.Hansasuta, P., Dong, T., Thananchai, H.,

Weekes, M., Willberg, C., Aldemir, H.,Rowland-Jones, S. and Braud, V. M.Recognition of HLA-A3 and HLA-A11 byKIR3DL2 is peptide-specific . . . . . . 1673

Hansen, M. B., see Galle, P.Hansen, W., see Bruder, D.Hara, T., see Takedatsu, H.Harari, A., Vallelian, F. and Pantaleo, G.

Phenotypic heterogeneity of antigen-specific CD4 T cells under different condi-tions of antigen persistence and antigenload . . . . . . . . . . . . . . . . . . . . . . . . . 3525

Harbecke, D., see Misslitz, A. C.Harcus, Y., see Balic, A.Hardeland, R., see Schlaf, G.Harle, J. R., see Pascal, V.Harmelin, A., see Topilski, I.Harris, H. E. and Andersson, U. Mini-

review: The nuclear protein HMGB1 as aproinflammatory mediator . . . . . . . . 1503

Hartmann, N., see Luckow, B.Hartz, S., see Fernekorn, U.Harvill, E. T., see Pishko, E. J.Hashiguchi, M., see Kuraoka, M.Haskova, Z., see Arancibia-Carcamo,

C. V.Haslett, C., see Heasman, S. J.Hassan, N. J., Barclay, A. N. and Brown, M.

H. Frontline: Optimal T cell activationrequires the engagement of CD6 andCD166 . . . . . . . . . . . . . . . . . . . . . . . . 930

Hastings, W. D., see Tumang, J. R.Hatano, M., see Seimiya, M.Hatherley, D. and Barclay, A. N. The CD200

and CD200 receptor cell surface proteinsinteract through their N-terminalimmunoglobulin-like domains . . . . . 1688

Haupt, R., see Vitale, C.

Hausding, M., Ho, I.-C., Lehr, H. A., Weig-mann, B., Lux, C., Schipp, M., Galle, P.R. and Finotto, S. A stage-specific func-tional role of the leucine zipper transcrip-tion factor c-Maf in lung Th2 cell differenti-ation. . . . . . . . . . . . . . . . . . . . . . . . . 3401

Hauser, H., see Jomantaite, I.Hauser, S. L., see von Büdingen, H.-C.Hauzenberger, E., Klominek, J. and Hol-

gersson, J. Anti-Gal IgG potentiates nat-ural killer cell migration across porcineendothelium via endothelial cell activationand increased natural killer cell motilitytriggered by CD16 cross-linking . . . 1154

He, L., see Cheng, W.-F.He, Q.-M., see Tan, G.-H.He, Z., Ehrnfelt, C., Kumagai-Braesch, M.,

Islam, K. B. and Holgersson, J. Aberrantexpression of § -Gal on primary humanendothelium does not confer susceptibil-ity to NK cell cytotoxicity or increased NKcell adhesion . . . . . . . . . . . . . . . . . . 1185

Heasman, S. J., Giles, K. M., Rossi, A. G.,Allen, J. E., Haslett, C. and Dransfield, I.Interferon- + suppresses glucocorticoidaugmentation of macrophage clearanceof apoptotic cells. . . . . . . . . . . . . . . 1752

Hegedüs, L., see Nielsen, C. H.Heifetz, A., see Herkel, J.Heine, I., see Schlaf, G.Heinrich, P. C., see Weissenbach, M.Heinzel, K., see Benz, C.Heinzmann, U., see Kirschnek, S.Heit, A., see Schmitz, F.Held, G., Matsuo, M., Epel, M., Gnjatic, S.,

Ritter, G., Lee, S. Y., Tai, T. Y., Cohen, C.J., Old, L. J., Pfreundschuh, M., Reiter,Y., Hoogenboom, H. R. and Renner, C.Dissecting cytotoxic T cell responsestowards the NY-ESO-1 protein by pep-tide/MHC-specific antibody fragments. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2919

Helgeland, L., Dissen, E., Dai, K.-Z., Midt-vedt, T., Brandtzaeg, P. and Vaage, J. T.Microbial colonization induces oligoclonalexpansions of intraepithelial CD8 T cells inthe gut . . . . . . . . . . . . . . . . . . . . . . . 3389

Helmby, H. and Grencis, R. K. Interleukin 1plays a major role in the development ofTh2-mediated immunity . . . . . . . . . 3674

Heneberg, P., see Tolarova, H.Hengartner, H., see Martinic, M. M.Henger, A., see Luckow, B.Henriksen, K. J., see Tang, Q.Hensbergen, P. J., see Verdijk, P.Hensmann, M., Li, C., Moss, C., Lindo, V.,

Greer, F., Watts, C., Ogun, S. A., Holder,A. A. and Langhorne, J. Disulfide bondsin merozoite surface protein 1 of themalaria parasite impede efficient antigenprocessing and affect the in vivo antibodyresponse . . . . . . . . . . . . . . . . . . . . . . 639

Herbelin, A., see Araujo, L. M.Herkel, J., Kam, N., Erez, N., Mimran, A.,

Heifetz, A., Eisenstein, M., Rotter, V. andCohen, I. R. Monoclonal antibody to aDNA-binding domain of p53 mimics

charge structure of DNA: anti-idiotypes tothe anti-p53 antibody are anti-DNA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3623

Hernandez, J., Schoeder, K., Blondelle, S.E., Pons, F. G., Lone, Y. C., Simora, A.,Langlade-Demoyen, P., Wilson, D. B.and Zanetti, M. Antigenicity and immuno-genicity of peptide analogues of a lowaffinity peptide of the human telomerasereverse transcriptase tumor antigen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2331

Hernandez, M. L. G., see Hernandez-Pando, R.

Hernandez-Pando, R., Aguilar, D., Hernan-dez, M. L. G., Orozco, H. and Rook, G.Pulmonary tuberculosis in BALB/c micewith non-functional IL-4 genes: changesin the inflammatory effects of TNF- § andin the regulation of fibrosis . . . . . . . . 174

Hernandez-Pando, R., see Baeza, I.Herzog, S., see Su, Y.-w.Hess, K. L., Donahue, A. C., Ng, K. L.,

Moore, T. I., Oak, J. and Fruman, D. A.Frontline: The p85 § isoform of phospho-inositide 3-kinase is essential for a subsetof B cell receptor-initiated signalingresponses . . . . . . . . . . . . . . . . . . . . 2968

Hessle, C., see Smits, H. H.Hewitt, S. L., High, F. A., Reiner, S. L.,

Fisher, A. G. and Merkenschlager, M.Nuclear repositioning marks the selectiveexclusion of lineage-inappropriate tran-scription factor loci during T helper celldifferentiation. . . . . . . . . . . . . . . . . . 3604

Hietala, M. A., Nandakumar, K. S., Per-sson, L., Fahlen, S., Holmdahl, R. andPekna, M. Complement activation byboth classical and alternative pathways iscritical for the effector phase of arthritis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1208

High, F. A., see Hewitt, S. L.Hill, S., see Zubairi, S.Hipskind, R. A., see Altman, A.Hirose, S., see Wen, X.Ho, I.-C., see Hausding, M.Hochweller, K. and Anderton, S. M. Sys-

temic administration of antigen-loadedCD40-deficient dendritic cells mimics sol-uble antigen administration . . . . . . . . 990

Hoebe, K., see Weighardt, H.Hoelzer, D., see Koyama, N.Hoffmann, R., see Luckow, B.Hofmann, M., Radsak, M., Rechtsteiner,

G., Wiemann, K., Günder, M., Bien-Gräter, U., Offringa, R., Toes, R. E. M.,Rammensee, H.-G. and Schild, H. T cellavidity determines the level of CTL activa-tion. . . . . . . . . . . . . . . . . . . . . . . . . . 1798

Hogaboam, C. M., see Ajuebor, M. N.Höglund, P., see Hall, H. T. L.Höglund, P., see Öberg, L.Holder, A. A., see Hensmann, M.Holgersson, J., see Hauzenberger, E.Holgersson, J., see He, Z.Holland, M. J., see Balic, A.Holmdahl, R., see Hietala, M. A.Holmgren, J., see Eriksson, K.

Author Index XI

Holtmeier, W., Geisel, W., Bernert, K., But-ler, J. E., Sinkora, M., Rehakova, Z., Sin-kora, J. and Caspary, W. F. Prenataldevelopment of the porcine TCR ˇ reper-toire: dominant expression of an invariantT cell receptor V ˇ 3-J ˇ 3 chain . . . . . 1941

Holzmann, B., see Feterowski, C.Holzmann, B., see Weighardt, H.Hong, J., Zang, Y. C. Q., Li, S., Rivera, V. M.

and Zhang, J. Z. Ex vivo detection ofmyelin basic protein-reactive T cells inmultiple sclerosis and controls using spe-cific TCR oligonucleotide probes . . . 870

Hong, S., see Yang, J.-Q.Hoogenboom, H. R., see Held, G.Hope, J. C., see Storset, A. K.Höpken, U. E., Droese, J., Li, J.-P., Joer-

gensen, J., Breitfeld, D., Zerwes, H.-G.and Lipp, M. The chemokine receptorCCR7 controls lymph node-dependentcytotoxic T cell priming in alloimmuneresponses . . . . . . . . . . . . . . . . . . . . . 461

Horan, T., see Oflazoglu, E.Horn, M. P., see Ebert, L. M.Hoth, M., see Tutsch, E.Houghton, M., see Masciopinto, F.Hougs, L., see Galle, P.Hourihane, J., see Strid, J.Howard, O. M. Z., see Chen, X.Howie, D., see Okamoto, S.Hsieh, C.-Y., see Cheng, W.-F.Hu, J., see Altman, A.Huang, C.-Y. and Kanagawa, O. Impact of

early expression of TCR § chain on thy-mocyte development. . . . . . . . . . . . 1532

Huang, X. and Yang, Y. Transient gain ofeffector function by CD8+ T cells undergo-ing peripheral tolerance to high-dose self-antigen. . . . . . . . . . . . . . . . . . . . . . . 1351

Huang, Y.-Y., see Shimamura, M.Huard, B., see Arlettaz, L.Hudecz, F., see Caccamo, N.Hudecz, F., see Medgyesi, D.Hue, S., see Andre, P.Hueber, W., Zeng, D., Sharpe, O., Robin-

son, W. H., Strober, S. and Utz, P. J.Characterization of novel antigens recog-nized by serum autoantibodies from anti-CD1 TCR-transgenic lupus mice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1654

Hugues, S., see Ferlin, W. G.Hulbert, C., see Kendall, P. L.Hung, C.-F., see Cheng, W.-F.Hünig, T., see van den Brandt, J.Hunt, J. R. F., see Adams, V. C.Hunziker, L., see Bachmann, M. F.Huseby, E., Kappler, J. and Marrack, P.

Commentary: TCR–MHC/peptide interac-tions: kissing-cousins or a shotgun wed-ding? . . . . . . . . . . . . . . . . . . . . . . . . 1243

Hyland, J. M., see O’Keeffe, J.Ibanez, M., see Baeza, I.Ibnou-Zekri, N., see Kuroki, A.Ichikawa, A., see Tanaka, S.Ierna, M. X., see Scales, H. E.Iglesias, T., see Riol-Blanco, L.Ihalainen, N., see Pajusto, M.

Im, J. S., see Dao, T.Im, S.-Y., see Seo, K. H.Imhof, B. A., see Legler, D. F.Inman, M. D., see Swirski, F. K.Ishida, N., see Yamada, M.Ishikawa, J., see Yamada, M.Ishikawa, S., see Sato, T.Islam, K. B., see He, Z.Islam, T. C., see Lindvall, J. M.Ito, T., see Sato, T.Ivanyi, J., see Caccamo, N.Ivanyi, J., see Dieli, F.Izui, S., see Cortes-Hernandez, J.Izui, S., see Kuroki, A.Jackson, S. S., see McKay, P. F.Jacob, M.-C., see Chaperot, L.Jacobs, T., Plate, T., Gaworski, I. and Fle-

ischer, B. CTLA-4-dependent mecha-nisms prevent T cell induced-liver pathol-ogy during the erythrocyte stage of Plas-modium berghei malaria . . . . . . . . . . 972

Jacobsen, H., see Rich, C.Jalkanen, S., see Yegutkin, G. G.James, D., see Dery, R. E.Jang, M.-H., see Ferlin, W. G.Jang, M.-J., see Lee, S.-Y.Jaramillo, A., see Narayanan, K.Jenkins, M. K., see Khoruts, A.Jenkins, M. K., see Park, H.-S.Jerne, N. K. The somatic generation of

immune recognition. . . . . . . . . . . . . 1234Jessup, H. K., see Oflazoglu, E.Jeurissen, A., Wuyts, G., Kasran, A.,

Ramdien-Murli, S., Blanckaert, N.,Boon, L., Ceuppens, J. L. and Bossuyt,X. The human antibody response to pneu-mococcal capsular polysaccharides isdependent on the CD40-CD40 ligandinteraction . . . . . . . . . . . . . . . . . . . . . 850

Ji, H., see Okamoto, S.Jiang, M., see Wang, L.Jiang, Y., see Wen, X.Jiao, L., see Han, X.Jin, Y.-J., see Su, M. W.-C.Joachim, R., see Zenclussen, A. C.Joergensen, J., see Höpken, U. E.Joergensen, J., see Luckow, B.Johansen, P., Stamou, P., Tascon, R. E.,

Lowrie, D. B. and Stockinger, B. CD4 Tcells guarantee optimal competitive fit-ness of CD8 memory T cells . . . . . . . . 91

Johansson, A.-K., Sergejeva, S.,Sjöstrand, M., Lee, J. J. and Lötvall, J.Allergen-induced traffic of bone marroweosinophils, neutrophils and lymphocytesto airways . . . . . . . . . . . . . . . . . . . . 3135

Johansson, S., see Öberg, L.Johnson, J. R., see Swirski, F. K.Johnson-Leger, C., see Legler, D. F.Jomantaite, I., Dikopoulos, N., Kröger, A.,

Leithäuser, F., Hauser, H., Schirmbeck,R. and Reimann, J. Hepatic dendritic cellsubsets in the mouse . . . . . . . . . . . . 355

Jondal, M., see Chen, L.Jones, M., see Adkins, B.Jones, R., see Rich, C.Jonsson, J. R., see Ward, S. M.

Jonuleit, H., see Stassen, M.Joossens, S., see Gijsbers, K.Joseph, C., see Pulendran, B.Jourdan, G., see Preynat-Seauve, O.Juarez, T., see Andre, P.Judkowski, V., Krakowski, M., Rodriguez,

E., Mocnick, L., Santamaria, P. and Sar-vetnick, N. Increased islet antigen pre-sentation leads to type-1 diabetes in micewith autoimmune susceptibility . . . . 1031

Julkunen, I., see Coccia, E. M.Jumaa, H., see Su, Y.-w.Jung, G., see Scheel, B.Jung, H. H., see Seo, K. H.Jung, M., Sabat, R., Krätzschmar, J., Sei-

del, H., Wolk, K., Schönbein, C., Schütt,S., Friedrich, M., Döcke, W.-D., Asadul-lah, K., Volk, H.-D. and Grütz, G. Expres-sion profiling of IL-10-regulated genes inhuman monocytes and peripheral bloodmononuclear cells from psoriatic patientsduring IL-10 therapy . . . . . . . . . . . . . 481

Jung, T., see Beinhauer, B. G.Junnikkala, S., see Hakulinen, J.Junt, T., see Ludewig, B.Jurk, M., see Vollmer, J.Jusek, G., see Weighardt, H.Kaer, L. V., see Yang, J.-Q.Kaiserlian, D., see Chapat, L.Kaiser-Moore, S., see Feterowski, C.Kaisho, T., see Yamada, M.Källberg, E., see Wrammert, J.Kallinich, T., see Stock, P.Kalos, M., see Friedman, R. S.Kam, N., see Herkel, J.Kamata, T., see Oida, E.Kaminogawa, S., see Kuraoka, M.Kaminski, S., see Altman, A.Kämpgen, E., see Eggert, A. O.Kamradt, T., see Kretschmer, U.Kamradt, T., see Misslitz, A. C.Kan, B., see Tan, G.-H.Kanagawa, O., see Huang, C.-Y.Kanagawa, O., see Suri, A.Kanaya, S., Nemoto, E., Ogawa, T. and

Shimauchi, H. Porphyromonas gingivalislipopolysaccharides induce maturation ofdendritic cells with CD14+CD16+ pheno-type . . . . . . . . . . . . . . . . . . . . . . . . . 1451

Kang, C.-Y., see Chung, Y.Kanie, O., see Shimamura, M.Kaplan, B. E., see Zhu, X.Kappler, J., see Huseby, E.Kapsenberg, M. L., see Smits, H. H.Kapsenberg, M. L., see Vieira, P. L.Karaghiosoff, M., see Schleicher, U.Karpouzas, G. A., La Cava, A., Ebling, F.

M., Singh, R. R. and Hahn, B. H. Differ-ences between CD8+ T cells in lupus-prone (NZB × NZW) F1 mice and healthy(BALB/c × NZW) F1 mice may influenceautoimmunity in the lupus model . . 2489

Kärre, K., see Öberg, L.Kasahara, M., see Takahashi, T.Kasahara, M., see Watanabe, Y.Kasper, L. H., see Mennechet, F. J. D.Kasprowicz, V. O., see Barnes, E.

XII Author Index

Kasran, A., see Jeurissen, A.Kather, A., see Müller, D. B.Kato, T., Uchikawa, R., Yamada, M., Ari-

zono, N., Oikawa, S., Kawanishi, S.,Nishio, A., Nakase, H. and Kuribayashi,K. Environmental pollutant tributyltin pro-motes Th2 polarization and exacerbatesairway inflammation. . . . . . . . . . . . . 1312

Katz, G., see Gazit, R.Katz, G., see Markel, G.Katz, J. D., see Suri, A.Katzenell, A., see Gazit, R.Kaufmann, S. H. E., see Mittrücker, H.-W.Kaur, A., see Elkington, R.Kawamoto, S., see Yamada, M.Kawamura, K., see Seimiya, M.Kawanishi, S., see Kato, T.Kay, R. J., see Klinger, M. B.Kaye, P. M., see Zubairi, S.Kelly, A. P., see Mitchell, E. K.Kemeny, D. M., see Sawicka, E.Kendall, P. L., Woodward, E. J., Hulbert, C.

and Thomas, J. W. Peritoneal B cells gov-ern the outcome of diabetes in non-obesediabetic mice . . . . . . . . . . . . . . . . . . 2387

Kenna, T., see O’Keeffe, J.Kennett, M. J., see Pishko, E. J.Kenny, E., Mason, D., Saoudi, A., Pombo,

A. and Ramırez, F. CD8 § is an activationmarker for a subset of peripheral CD4 Tcells . . . . . . . . . . . . . . . . . . . . . . . . . 1262

Kerr, W., see Eason, D. D.Kessler, B., see Gil-Torregrosa, B. C.Khamlichi, A. A., see Glaudet, F.Khan, M., see Cunningham, A. F.Khandre, N. S., see Sade, H.Khanna, R., see Elkington, R.Khar, A., see Alli, R.Khare, M., see Mangalam, A. K.Khoruts, A., Osness, R. E. and Jenkins, M.

K. IL-1 acts on antigen-presenting cells toenhance the in vivo proliferation ofantigen-stimulated naive CD4 T cells via aCD28-dependent mechanism that doesnot involve increased expression of CD28ligands . . . . . . . . . . . . . . . . . . . . . . . 1085

Kikuchi, S., see Kuroki, A.Kikuchi, Y., see Wen, X.Kilmartin, B. and Reen, D. J. HSP60

induces self-tolerance to repeated HSP60stimulation and cross-tolerance to otherpro-inflammatory stimuli . . . . . . . . . 2041

Kim, B. S., see Lyman, M. A.Kim, H. J., see Erl, W.Kim, J.-W., see Lee, S.-Y.Kim, S., see Chung, Y.Kimber, I., see Strid, J.Kingsbury, G. A., see Vieira, P. L.Kipnis, J., see Avidan, H.Kirimanjeswara, G. S., see Pishko, E. J.Kirschnek, S., Scheffel, J., Heinzmann, U.

and Häcker, G. Necrosis-like cell deathinduced by bacteria in mouse macro-phages. . . . . . . . . . . . . . . . . . . . . . . 1461

Kirschning, C. J., see da Costa, C. U. P.Kirschning, C. J., see Hallatschek, W.Kiss, E., see Luckow, B.

Kiss, I., see Toth, B.Kita, T., see Oida, E.Kitabatake, M., see Sato, T.Kitzig, F., see Alvarez-Errico, D.Klapp, B. F., see Zenclussen, A. C.Klein, C., see de Kozak, Y.Klenerman, P. Commentary: T cells get by

with a little help from their friends. . . 313Klenerman, P., see Barnes, E.Klenerman, P., see Ward, S. M.Klinger, M. B., Guilbault, B. and Kay, R. J.

The RhoA- and CDC42-specific exchangefactor Dbs promotes expansion of imma-ture thymocytes and deletion of double-positive and single-positive thymocytes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 806

Klominek, J., see Hauzenberger, E.Knight, A. M., see Brooks, K.Knight, J. F., see Wu, H.Knop, J., see Seidel-Guyenot, W.Knop, J., see Stassen, M.Knowles, B., see Chen, W.Ko, H.-M., see Seo, K. H.Kobayashi, I., see Oida, E.Kobayashi, K., see Shimamura, M.Kobayashi, M., see Shimamura, M.Kobayashi, N., Takata, H., Yokota, S. and

Takiguchi, M. Down-regulation of CXCR4expression on human CD8+ T cells duringperipheral differentiation . . . . . . . . . 3370

Kochik, S. A., see Gebe, J. A.Kodama, M., see Palaniyandi, S. S.Koerten, H. K., see Verdijk, P.Kominski, D., see Lang, J. A.Koncz, G., see Medgyesi, D.Kong, H., see Mayne, M.Koning, F., see Verdijk, P.Konomi, A., see Tanaka, S.Kopf, M., see Bachmann, M. F.Korb, J., see Draberova, L.Körner, H., see Ritter, U.Korthauer, U., see Beinhauer, B. G.Koschella, M., see Marcolino, I.Kosiewicz, M. M., see Alard, P.Koskinen, K., see Yegutkin, G. G.Kourilsky, P., see Lemaıtre, F.Koyama, N., Hoelzer, D. and Ottmann, O.

G. Regulation of human IL-18 gene ex-pression: interaction of PU.1 with GC-boxbinding protein is involved in human IL-18expression in myeloid cells . . . . . . . . 817

Krajina, T., Leithäuser, F. and Reimann, J.MHC class II-independent CD25+ CD4+

CD8 § g + § g T cells attenuate CD4+ T cell-induced transfer colitis . . . . . . . . . . . 705

Krakowski, M., see Judkowski, V.Krammer, P. H., see Baumann, S.Krammer, P. H., see Li-Weber, M.Krammer, P. H., see Shinbori, T.Krätzschmar, J., see Jung, M.Kraus, M., see Maehr, R.Krawczyk, M., see LeibundGut-

Landmann, S.Krco, C., see Mangalam, A. K.Krebs, P., see Ludewig, B.Kremer, B., see Averbeck, M.Krensky, A. M., see Farouk, S. E.

Kretschmer, U., Bonhagen, K., Debes, G.F., Mittrücker, H.-W., Erb, K. J., Liesen-feld, O., Zaiss, D., Kamradt, T., Syrbe, U.and Hamann, A. Expression of selectinligands on murine effector and IL-10-producing CD4+ T cells from non-infectedand infected tissues . . . . . . . . . . . . 3070

Kretzler, M., see Luckow, B.Krieg, A. M., see Vollmer, J.Kristensen, N. N., see Gad, M.Kröger, A., see Jomantaite, I.Kronenberg, M., see Lisbonne, M.Kronenberg, M., see Stenström, M.Kronenberg, M., see Zaccone, P.Kruhøffer, M., see Vermijlen, D.Kruse, A., see Fernekorn, U.Ku, C.-L., see Feinberg, J.Kubach, J., see Stassen, M.Kuchroo, V., see Petersen, T. R.Kuchroo, V. K., see Ellmerich, S.Kuchroo, V. K., see Greve, B.Kulberg, S., see Storset, A. K.Kullberg, B. J., see Netea, M. G.Kumagai-Braesch, M., see He, Z.Kumar, V., see Lian, R. H.Kupfer, R., see Wheat, W.Kuprash, D. V., see Shakhov, A. N.Kuraoka, M., Hashiguchi, M., Hachimura,

S. and Kaminogawa, S. CD4–c-kit–CD3 4 –IL-2R § + Peyer’s patch cells are anovel cell subset which secrete IL-5 inresponse to IL-2: implications for their rolein IgA production . . . . . . . . . . . . . . . 1920

Kuribayashi, K., see Kato, T.Kuroki, A., Moll, T., Lopez-Hoyos, M.,

Fossati-Jimack, L., Ibnou-Zekri, N.,Kikuchi, S., Merino, J., Merino, R. andIzui, S. Enforced Bcl-2 expression in Blymphocytes induces rheumatoid factorand anti-DNA production, but the Yaamutation promotes only anti-DNA produc-tion. . . . . . . . . . . . . . . . . . . . . . . . . . 1077

Kurtis, C., see Yegutkin, G. G.Kuzin, I. I., Ugine, G. D., Barth, R. K.,

Shultz, L. D., Nahm, M. H., Young, F. M.and Bottaro, A. A new murine model ofhumoral immunodeficiency specificallyaffects class switching to T-independentantigens . . . . . . . . . . . . . . . . . . . . . . 1807

Kwak, J.-Y., see Lee, S.-Y.Kyewski, B., see Baumann, S.La Cava, A., see Karpouzas, G. A.La Mendola, C., see Caccamo, N.Lafarge, X., see Pascal, V.Laman, J. D., see de Vos, A. F.Lambeau, G., see Perrin-Cocon, L.Lamping, N., see Hallatschek, W.Lande, R., see Coccia, E. M.Lane, P., see Erlandsson, L.Lang, A. B., see Ebert, L. M.Lang, J. A., Kominski, D., Bellgrau, D. and

Scheinman, R. I. Partial activation pre-cedes apoptotic death in T cells harboringan IAN gene mutation . . . . . . . . . . . 2396

Lang, R., see Mariani, M.Lang, R., see Schmitz, F.Lang, R., see Weighardt, H.

Author Index XIII

Langhorne, J., see Hensmann, M.Langlade-Demoyen, P., see Hernandez, J.Lanino, E., see Vitale, C.Lara, M., see Baeza, I.Larmonier, N., see Ghiringhelli, F.Laucht, M., see Vollmer, J.Lauletta, G., see Sansonno, D.Laurence, A., Astoul, E., Hanrahan, S.,

Totty, N. and Cantrell, D. Identification ofpro-interleukin 16 as a novel target ofMAP kinases in activated T lymphocy-tes . . . . . . . . . . . . . . . . . . . . . . . . . . . 587

Lauvau, G. and Glaichenhaus, N. Mini-review: Presentation of pathogen-derivedantigens in vivo . . . . . . . . . . . . . . . . . 913

Lawrence, C. E., see Scales, H. E.Lawrence, W. A., see Oflazoglu, E.Laws, A. M. and Osborne, B. A. p53 regu-

lates thymic Notch1 activation . . . . . 726Layland, L. E., Wulferink, M., Dierkes, S.

and Gleichmann, E. Drug-induced auto-antibody formation in mice: triggering byprimed CD4+CD25– T cells, prevention byprimed CD4+CD25+ T cells . . . . . . . . . 36

Le Friec, G., see Le Rond, S.Le Maoult, J., see Le Rond, S.Le Rond, S., Le Maoult, J., Creput, C.,

Menier, C., Deschamps, M., Le Friec, G.,Amiot, L., Durrbach, A., Dausset, J.,Carosella, E. D. and Rouas-Freiss, N.Alloreactive CD4+ and CD8+ T cellsexpress the immunotolerant HLA-G mole-cule in mixed lymphocyte reactions: invivo implications in transplanted patients. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 649

Le, T., see Ajuebor, M. N.Leanderson, T., see Wrammert, J.Lear, T. L., see Takahashi, T.Lebduska, P., see Draberova, L.Lebecque, S., see Chaperot, L.Lechartier, H., see Birebent, B.Lechler, R., see Golshayan, D.Leclerc, T., see Feinberg, J.Lee, C.-N., see Cheng, W.-F.Lee, D.-S., see Moon, E.-Y.Lee, H.-K., see Seo, K. H.Lee, J. J., see Johansson, A.-K.Lee, J. K., Boles, K. S. and Mathew, P. A.

Molecular and functional characterizationof a CS1 (CRACC) splice variant expres-sed in human NK cells that does not con-tain immunoreceptor tyrosine-basedswitch motifs . . . . . . . . . . . . . . . . . . 2791

Lee, K. K., see Bueno, C.Lee, M. M. K., see Tian, Y.Lee, M.-J., see Lee, S.-Y.Lee, S. Y., see Held, G.Lee, S.-Y., Oh, J.-Y., Lee, M.-J., Jang, M.-

J., Park, H.-Y., Kim, J.-W., Min, D. S.,Park, Y.-M., Chang, Y.-C., Bae, Y.-S. andKwak, J.-Y. Anti-apoptotic mechanismand reduced expression of phospholipaseD in spontaneous and Fas-stimulatedapoptosis of human neutrophils . . . 2760

Lee-Chan, E., see Bueno, C.Leelawong, M., see Oswald-Richter, K.Leenen, P. J. M., see Geutskens, S. B.

Lefort, J., see Araujo, L. M.Lefrancois, L., see D’Souza, W. N.Legler, D. F., Johnson-Leger, C., Wiedle,

G., Bron, C. and Imhof, B. A. The § v g 3integrin as a tumor homing ligand for lym-phocytes . . . . . . . . . . . . . . . . . . . . . 1608

Lehr, H. A., see Hausding, M.Lehr, H. A., see Siegmund, B.Lehuen, A., see Ferlin, W. G.Lehuen, A., see Stenström, M.LeibundGut-Landmann, S., Waldburger,

J.-M., Krawczyk, M., Otten, L. A., Suter,T., Fontana, A., Acha-Orbea, H. andReith, W. Mini-review: Specificity andexpression of CIITA, the master regulatorof MHC class II genes . . . . . . . . . . . 1513

Leite-de-Moraes, M. C., see Araujo, L. M.Leite-de-Moraes, M. C., see Lisbonne, M.Leithäuser, F., see Jomantaite, I.Leithäuser, F., see Krajina, T.Lemaıtre, F., see Dogan, I.Lemaıtre, F., Viguier, M., Cho, M.-S., Four-

neau, J.-M., Maillere, B., Kourilsky, P.,van Endert, P. M. and Ferradini, L.Detection of low-frequency humanantigen-specific CD4+ T cells using MHCclass II multimer bead sorting andimmunoscope analysis . . . . . . . . . . 2941

Lemoli, R. M., see Rutella, S.Lemonnier, F. A., see Pajot, A.Lenardo, M. J., see Lobito, A. A.Lennon-Dumenil, A. M., see Gil-Torre-

grosa, B. C.Lens, S., see Tardivel, A.Lens, S. M. A., see Eldering, E.Leo, O., see de Heusch, M.Leone, G., see Rutella, S.Lepault, F., see Cotta-de-Almeida, V.Leslie, R. G. Q., see Nielsen, C. H.Letvin, N. L., see McKay, P. F.Levo, Y., see Topilski, I.Levy, R. B., see Adkins, B.Leyva, E., see Baeza, I.Li, B.-L., see Eriksson, K.Li, C., see Hensmann, M.Li, H.-L., see Tan, G.-H.Li, J., see Tan, G.-H.Li, J.-P., see Höpken, U. E.Li, J.-P., see Luckow, B.Li, S., see Hong, J.Lian, R. H., Chin, R. K., Nemeth, H. E.,

Libby, S. L., Fu, Y.-X. and Kumar, V.A role for lymphotoxin in the acquisition ofLy49 receptors during NK cell develop-ment . . . . . . . . . . . . . . . . . . . . . . . . 2699

Libby, S. L., see Lian, R. H.Licence, S., see Erlandsson, L.Lieberman, N., see Markel, G.Liesenfeld, O., see Kretschmer, U.Liesenfeld, O., see Vossenkämper, A.Lifton, M. A., see McKay, P. F.Lin, C.-H., see Nolte-‘t Hoen, E. N. M.Lin, H., Nieda, M. and Nicol, A. J. Differen-

tial proliferative response of NKT cell sub-populations to in vitro stimulation in pres-ence of different cytokines . . . . . . . 2664

Lin, L., Gerth, A. J. and Peng, S. L. CpG

DNA redirects class-switching towards“Th1-like” Ig isotype production via TLR9and MyD88 . . . . . . . . . . . . . . . . . . . 1483

Lindblad, M., see Eriksson, K.Lindo, V., see Hensmann, M.Lindvall, J. M., Blomberg, K. E. M.,

Berglöf, A., Yang, Q., Smith, C. I. E. andIslam, T. C. Gene expression profile of Bcells from Xid mice and Btk knockoutmice. . . . . . . . . . . . . . . . . . . . . . . . . 1981

Ling, K.-L., see Markel, G.Linington, C., see Mathey, E.Link, C., Gavioli, R., Ebensen, T., Canella,

A., Reinhard, E. and Guzman, C. A. TheToll-like receptor ligand MALP-2 stimu-lates dendritic cell maturation and modu-lates proteasome composition and activ-ity . . . . . . . . . . . . . . . . . . . . . . . . . . . . 899

Link, J. M., see Rich, C.Lipford, G. B., see Rutz, M.Lipp, M., see Francavilla, V.Lipp, M., see Höpken, U. E.Lippuner, C., see Misslitz, A. C.Lisbonne, M., Hachem, P., Tonanny, M.-B.,

Fourneau, J.-M., Sidobre, S., Kronen-berg, M., Van Endert, P., Dy, M., Schnei-der, E. and Leite-de-Moraes, M. C. Invivo activation of invariant V § 14 naturalkiller T cells by § -galactosylceramidesequentially induces Fas-dependent and-independent cytotoxicity . . . . . . . . 1381

Litjens, N. H. R., Rademaker, M., Ravens-bergen, B., Rea, D., van der Plas, M. J.A., Thio, B., Walding, A., van Dissel, J. T.and Nibbering, P. H. Monomethylfuma-rate affects polarization of monocyte-derived dendritic cells resulting indown-regulated Th1 lymphocyteresponses . . . . . . . . . . . . . . . . . . . . . 565

Litman, G. W., see Eason, D. D.Litman, R. T., see Eason, D. D.Liu, C., see Sheard, M. A.Liu, G., Ng, H., Akasaki, Y., Yuan, X., Ehte-

sham, M., Yin, D., Black, K. L. and Yu, J.S. Small interference RNA modulation ofIL-10 in human monocyte-derived den-dritic cells enhances the Th1 response. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1680

Liu, H., see Yang, J.-Q.Liu, M., see Vollmer, J.Liu, Y., see Zheng, X.Li-Weber, M., Giaisi, M., Baumann, S.,

Palfi, K. and Krammer, P. H. NF- ‹ B syn-ergizes with NF-AT and NF-IL6 in activa-tion of the IL-4 gene in T cells. . . . . 1111

Lobito, A. A., Lopes, M. F. and Lenardo, M.J. Ectopic T cell receptor expressioncauses B cell immunodeficiency in trans-genic mice . . . . . . . . . . . . . . . . . . . . . 890

Locati, M., see Martinez, F. O.Lochner, M., see Vossenkämper, A.Lone, Y. C., see Hernandez, J.Lone, Y.-C., see Pajot, A.Longo, I., see Riol-Blanco, L.Longo, N., see Riol-Blanco, L.Loos, M., see Cortes-Hernandez, J.Lopes, M. F., see Lobito, A. A.

XIV Author Index

Lopez, M., see Compte, E.Lopez-Botet, M., see Alvarez-Errico, D.Lopez-Hoyos, M., see Kuroki, A.Lord, J. M., see Smith, D. C.Lorho, R., see Birebent, B.Loser, K., see Bruder, D.Loser, K., Mehling, A., Apelt, J., Ständer, S.,

Andres, P. G., Reinecker, H.-C., Eing, B.R., Skryabin, B. V., Varga, G., Schwarz, T.and Beissert, S. Enhanced contact hyper-sensitivity and antiviral immune responsesin vivo by keratinocyte-targeted overex-pression of IL-15. . . . . . . . . . . . . . . . 2022

Lotteau, V., see Perrin-Cocon, L.Lotti, F., see Eramo, A.Lötvall, J., see Johansson, A.-K.Lotz, M., see Su, Y.-w.Lowrie, D. B., see Johansen, P.Luangsay, S., see Mennechet, F. J. D.Lucas, M., see Barnes, E.Lucas, M., see Ward, S. M.Luckow, B., Joergensen, J., Chilla, S.,

Li, J.-P., Henger, A., Kiss, E., Wieczorek,G., Roth, L., Hartmann, N., Hoffmann,R., Kretzler, M., Nelson, P. J., de Lema,G. P., Maier, H., Wurst, W., Balling, R.,Pfeffer, K., Gröne, H.-J., Schlöndorff, D.and Zerwes, H.-G. Reduced intragraftmRNA expression of matrix metallopro-teinases Mmp3, Mmp12, Mmp13 andAdam8, and diminished transplant arterio-sclerosis in Ccr5-deficient mice . . . 2568

Ludanyi, K., see Toth, B.Ludewig, B., Krebs, P., Junt, T., Metters,

H., Ford, N. J., Anderson, R. M. andBocharov, G. Determining control param-eters for dendritic cell-cytotoxic T lym-phocyte interaction . . . . . . . . . . . . . 2407

Luer, C. A., see Eason, D. D.Lunardi, C., see Oliveri, M.Luo, D., see Vermijlen, D.Luppa, P., see Rutz, M.Lustgarten, J., Dominguez, A. L. and

Cuadros, C. The CD8+ T cell repertoireagainst Her-2/neu antigens in neu trans-genic mice is of low avidity with antitumoractivity . . . . . . . . . . . . . . . . . . . . . . . . 752

Lux, C., see Hausding, M.Lyman, M. A., Myoung, J., Mohindru, M.

and Kim, B. S. Quantitative, not quali-tative, differences in CD8+ T cellresponses to Theiler’s murine encephalo-myelitis virus between resistant C57BL/6and susceptible SJL/J mice . . . . . . 2730

Lynch, N. J., see Roos, A.Ma, M., see Palaniyandi, S. S.Mack, M., see Feterowski, C.Mackay, F., see Tardivel, A.Mackus, W. J. M., see Eldering, E.MacLennan, I. C. M., see Cunningham, A.

F.MacLennan, I. C. M., see Cunningham,

A. F.Madrenas, J., see Bueno, C.Madsen, H. O., see Roos, A.Maehr, R., Kraus, M. and Ploegh, H. L.

Mice deficient in invariant-chain and MHC

class II exhibit a normal mature B2 cellcompartment . . . . . . . . . . . . . . . . . . 2230

Maenaka, K., see Wada, H.Mages, J., see Chaneva, S.Mages, J., see Schmitz, F.Mages, J., see Weighardt, H.Maier, H., see Luckow, B.Maillere, B., see Lemaıtre, F.Maizels, R. M., see Balic, A.Malavasi, F., see Fedele, G.Maliszewski, C., see de Heusch, M.Mallet, F., see Duhen, T.Mancuso, S., see Rutella, S.Mandelboim, O., see Gazit, R.Mandelboim, O., see Markel, G.Mandelboim, O., see Wald, O.Mangalam, A. K., Khare, M., Krco, C., Rod-

riguez, M. and David, C. Identification ofT cell epitopes on human proteolipid pro-tein and induction of experimental autoim-mune encephalomyelitis in HLA class II-transgenic mice . . . . . . . . . . . . . . . . . 280

Manning, S., see Okamoto, S.Mansour Haeryfar, S. M., see Chen, W.Mantamadiotis, T., see Baumann, S.Mantovani, A., see Martinez, F. O.Mao, Y.-Q., see Tan, G.-H.Marcenaro, E., see Falco, M.Marche, P. N., see Preynat-Seauve, O.Marcolino, I., Przybylski, G. K., Koschella,

M., Schmidt, C. A., Voehringer, D.,Schlesier, M. and Pircher, H. Frequentexpression of the natural killer cell recep-tor KLRG1 in human cord blood T cells:correlation with replicative history. . 2672

Mariani, M., Lang, R., Binda, E., Panina-Bordignon, P. and D’Ambrosio, D. Domi-nance of CCL22 over CCL17 in inductionof chemokine receptor CCR4 desensitiza-tion and internalization on human Th2cells . . . . . . . . . . . . . . . . . . . . . . . . . . 231

Mariotti, A., see Rutella, S.Markel, G., see Gazit, R.Markel, G., Achdout, H., Katz, G., Ling, K.-

L., Salio, M., Gruda, R., Gazit, R., Miz-rahi, S., Hanna, J., Gonen-Gross, T.,Arnon, T. I., Lieberman, N., Stren, N.,Nachmias, B., Blumberg, R. S., Steuer,G., Blau, H., Cerundolo, V., Mussaffi, H.and Mandelboim, O. Biological functionof the soluble CEACAM1 protein andimplications in TAP2-deficient patients. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2138

Marrack, P., see Huseby, E.Marras, D., see Falco, M.Marshall, A. S. J. and Gordon, S. Commen-

tary: C-type lectins on the macrophagecell surface – recent findings. . . . . . . . 18

Mårtensson, I.-L., see Erlandsson, L.Martin, F., see Ghiringhelli, F.Martin, S. F., see Averbeck, M.Martinelli, R., see Adams, V. C.Martinez, F. O., Sironi, M., Vecchi, A.,

Colotta, F., Mantovani, A. and Locati, M.IL-8 induces a specific transcriptional pro-file in human neutrophils: synergism withLPS for IL-1 production. . . . . . . . . . 2286

Martınez-A., C., see Carvalho-Pinto, C.Martınez-Munoz, L., see Arce, I.Martinic, M. M., Rocha, B., McCoy, K. D.,

Hengartner, H. and Zinkernagel, R. M.Role of TCR-restricting MHC density andthymic environment on selection and sur-vival of cells expressing low-affinity T cellreceptors . . . . . . . . . . . . . . . . . . . . . 1041

Maruoka, T., see Watanabe, Y.Masaie, H., see Yamada, M.Masciopinto, F., Giovani, C., Campagnoli,

S., Galli-Stampino, L., Colombatto, P.,Brunetto, M., Yen, T. S. B., Houghton,M., Pileri, P. and Abrignani, S. Associa-tion of hepatitis C virus envelope proteinswith exosomes . . . . . . . . . . . . . . . . 2834

Masewicz, S. A., see Gebe, J. A.Mason, D., see Kenny, E.Masterman, K.-A., see Chen, W.Mastroeni, P., see Mitchell, E. K.Mastroeni, P., see Zaccone, P.Masurel, A., see Perrin-Cocon, L.Mathew, M. K., see Sade, H.Mathew, P. A., see Lee, J. K.Mathey, E., Breithaupt, C., Schubart,

A. S. and Linington, C. Commentary:Sorting the wheat from the chaff: identify-ing demyelinating components of themyelin oligodendrocyte glycoprotein(MOG)-specific autoantibody repertoire. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2065

Mathison, R., see Dery, R. E.Matsuda, T., see Tomiyama, H.Matsue, H., see Matsushima, H.Matsumoto, N., see Wada, H.Matsumoto, S., see Takedatsu, H.Matsuo, M., see Held, G.Matsushima, H., Yamada, N., Matsue, H.

and Shimada, S. The effects ofendothelin-1 on degranulation, cytokine,and growth factor production by skin-derived mast cells . . . . . . . . . . . . . . 1910

Matsushima, K., see Sato, T.Matsushima, K., see Yanaba, K.Matsushita, M., see Roos, A.Matsuzawa, Y., see Yamada, M.Mattila, P. S., see Pajusto, M.Mattner, J., see Schleicher, U.Mautner, J., Pich, D., Nimmerjahn, F., Milo-

sevic, S., Adhikary, D., Christoph, H.,Witter, K., Bornkamm, G. W., Ham-merschmidt, W. and Behrends, U.Epstein-Barr virus nuclear antigen 1evades direct immune recognition byCD4+ T helper cells . . . . . . . . . . . . . 2500

Mayne, M., Moffatt, T., Kong, H., McLaren,P. J., Fowke, K. R., Becker, K. G.,Namaka, M., Schenck, A., Bardoni, B.,Bernstein, C. N. and Melanson, M.CYFIP2 is highly abundant in CD4+ cellsfrom multiple sclerosis patients and isinvolved in T cell adhesion . . . . . . . 1217

Mazerolles, F., see Trucy, M.McAdam, S., see Bell, S. E.McBride, J. M., see Beinhauer, B. G.McCoy, K. D., see Martinic, M. M.McGuirk, P., see Byrne, P.

Author Index XV

McKay, P. F., Barouch, D. H., Santra, S.,Sumida, S. M., Jackson, S. S., Gorgone,D. A., Lifton, M. A. and Letvin, N. L.Recruitment of different subsets ofantigen-presenting cells selectively mod-ulates DNA vaccine-elicited CD4+ andCD8+ T lymphocyte responses . . . . 1011

McLaren, P. J., see Mayne, M.McPherson, M. J., see Yegutkin, G. G.Meade, J., Tybulewicz, V. L. J. and Turner,

M. The tyrosine kinase Syk is required forlight chain isotype exclusion but dispens-able for the negative selection of B cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1102

Medgyesi, D., Uray, K., Sallai, K., Hudecz,F., Koncz, G., Abramson, J., Pecht, I.,Sarmay, G. and Gergely, J. Functionalmapping of the Fc + RII binding site onhuman IgG1 by synthetic peptides. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1127

Mehling, A., see Loser, K.Mehrotra, S., see Chhabra, A.Meijer, C. J. L. M., see van Galen, J. C.Meißner, A., see Ritter, U.Melanson, M., see Mayne, M.Melief, M.-J., see de Vos, A. F.Mellado, M., see Carvalho-Pinto, C.Mendola, C. L., see Dieli, F.Menge, T., see von Büdingen, H.-C.Menier, C., see Le Rond, S.Mennechet, F. J. D., Kasper, L. H., Rachi-

nel, N., Minns, L. A., Luangsay, S., Van-dewalle, A. and Buzoni-Gatel, D. Intesti-nal intraepithelial lymphocytes preventpathogen-driven inflammation andregulate the Smad/T-bet pathway of lam-ina propria CD4+ T cells. . . . . . . . . . 1059

Merani, S., see Dery, R. E.Meraviglia, S., see Caccamo, N.Meraviglia, S., see Dieli, F.Meri, S., see Hakulinen, J.Merino, J., see Kuroki, A.Merino, R., see Kuroki, A.Merkenschlager, M., see Hewitt, S. L.Messina, C. G. M., see Eramo, A.Metharom, P., see Velten, F. W.Metters, H., see Ludewig, B.Metwali, A., see Elliott, D. E.Metzger, J., see Rutz, M.Meza-Romero, R., see Rich, C.Michaelsson, J., see Öberg, L.Michel, M.-L., see Pajot, A.Michel, S., see Toth, B.Midtvedt, T., see Helgeland, L.Miethke, T., see da Costa, C. U. P.Miles, J. J., see Green, K. J.Millo, R., see Oliveri, M.Mills, K. H. G., see Byrne, P.Milne, C. D., Fleming, H. E. and Paige, C. J.

Frontline: IL-7 does not prevent pro-B/pre-B cell maturation to the immature/sIgM+ stage . . . . . . . . . . . . . . . . . . . 2647

Milosevic, S., see Mautner, J.Mimran, A., see Herkel, J.Min, D. S., see Lee, S.-Y.Mincheva-Nilsson, L., see Farouk,

S. E.

Mingari, M. C., see Vitale, C.Mingari, M. C., see Fogli, M.Mingari, M. C., see Vitale, C.Minns, L. A., see Mennechet, F. J. D.Missale, G., Papagno, L., Penna, A., Pilli,

M., Zerbini, A., Vitali, P., Pieroni, G.,Urbani, S., Uggeri, J., Pinheiro, S.,Rowland-Jones, S. and Ferrari, C. Par-enteral exposure to high HIV viremia leadsto virus-specific T cell priming without evi-dence of infection . . . . . . . . . . . . . . 3208

Misslitz, A. C., Bonhagen, K., Harbecke,D., Lippuner, C., Kamradt, T. and Aebis-cher, T. Two waves of antigen-containingdendritic cells in vivo in experimentalLeishmania major infection . . . . . . . . 715

Mitchell, E. K., Mastroeni, P., Kelly, A. P.and Trowsdale, J. Inhibition of cell sur-face MHC class II expression by Salmo-nella . . . . . . . . . . . . . . . . . . . . . . . . . 2559

Mitsuyama, K., see Takedatsu, H.Mittrücker, H.-W. and Kaufmann, S. H. E.

Mini-review: Regulatory T cells and infec-tion: suppression revisited . . . . . . . . 306

Mittrücker, H.-W., see Kretschmer, U.Miyasaka, K., Hanayama, R., Tanaka, M.

and Nagata, S. Expression of milk fatglobule epidermal growth factor 8 inimmature dendritic cells for engulfment ofapoptotic cells . . . . . . . . . . . . . . . . . 1414

Miyawaki, S., see Oida, E.Mizrahi, S., see Gazit, R.Mizrahi, S., see Markel, G.Mizuno, K., see Verdijk, P.Mocnick, L., see Judkowski, V.Moffatt, T., see Mayne, M.Mohamadzadeh, M., see Pulendran, B.Mohanakumar, T., see Narayanan, K.Mohindru, M., see Lyman, M. A.Mohr, E., see Cunningham, A. F.Moll, T., see Kuroki, A.Mommaas, A. M., see Verdijk, P.Mondelli, M. U., see Accapezzato, D.Mondelli, M. U., see Francavilla, V.Monneron, D., see Coccia, E. M.Monroe, J. G. and Allman, D. Commentary:

Keeping track of pro-B cells: a new modelfor the effects of IL-7 during B cell devel-opment . . . . . . . . . . . . . . . . . . . . . . 2642

Moon, E.-Y., Han, Y. H., Lee, D.-S., Han, Y.-M. and Yu, D.-Y. Reactive oxygen speciesinduced by the deletion of peroxiredoxin II(PrxII) increases the number of thymo-cytes resulting in the enlargement of PrxII-null thymus . . . . . . . . . . . . . . . . . . . 2119

Moore, T. I., see Hess, K. L.Moreau, E., see Partidos, C. D.Moreau, J. F., see Pascal, V.Moretta, A., see Andre, P.Moretta, A., see Falco, M.Moretta, A., see Fogli, M.Moretta, A., see Vitale, M.Moretta, A. and Bottino, C. Commentary:

Regulated equilibrium between oppositesignals: a general paradigm for T cell func-tion?. . . . . . . . . . . . . . . . . . . . . . . . . 2084

Moretta, L., see Falco, M.

Moretta, L., see Fogli, M.Moretta, L., see Vitale, C.Moretta, L., see Vitale, M.Moretti, S., see Vitale, C.Morreale, G., see Vitale, C.Morris, C. M., see Seminario, M.-C.Moser, B., see Ebert, L. M.Moser, M., see de Heusch, M.Moshous, D., see Poinsignon, C.Mosmann, T., see Yang, L.Moss, C., see Hensmann, M.Mougneau, E., see Ferlin, W. G.Mueller, C., see Baumann, R.Mukaida, N., see Yanaba, K.Mukherji, B., see Chhabra, A.Müller, C., see Stassen, M.Müller, D. B., Raftery, M. J., Kather, A.,

Giese, T. and Schönrich, G. Frontline:Induction of apoptosis and modulation ofc-FLIPL and p53 in immature dendriticcells infected with herpes simplex virus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 941

Müller, M., see Schleicher, U.Muller, S., see Partidos, C. D.Munoz, J. R., see Roos, A.Murakami, T., see Chen, X.Murdaca, G., see Fogli, M.Murphy, K. M., see Berenson, L. S.Murphy, P. M., see Yanaba, K.Murphy, T. L., see Berenson, L. S.Müschen, M., see Su, Y.-w.Muso, E., see Oida, E.Mussaffi, H., see Markel, G.Mustelin, T., see Vang, T.Mycko, M., see Ellmerich, S.Myklebust, S., see Vang, T.Myoung, J., see Lyman, M. A.Naber, T. H. J., see Netea, M. G.Nachmias, B., see Markel, G.Nagata, S., see Miyasaka, K.Nagler, A., see Franitza, S.Nahm, M. H., see Kuzin, I. I.Nahori, M.-A., see Araujo, L. M.Nakamura, K., see Wen, X.Nakase, H., see Kato, T.Nam, S., see Vieira, P. L.Namaka, M., see Mayne, M.Nance, S., Cross, R. and Fitzpatrick, E.

Chemokine production during hypersensi-tivity pneumonitis . . . . . . . . . . . . . . . 677

Nandakumar, K. S., see Hietala, M. A.Nanni, M., see Andre, P.Narayanan, K., Jaramillo, A., Phelan, D. L.

and Mohanakumar, T. Pre-exposure tosub-saturating concentrations of HLAclass I antibodies confers resistance toendothelial cells against antibodycomplement-mediated lysis by regulatingBad through the phosphatidylinositol 3-kinase/Akt pathway . . . . . . . . . . . . . 2303

Naud, M.-C., see de Kozak, Y.Nauta, A. J., see Roos, A.Naveh, Y., see Topilski, I.Navone, R., see Oliveri, M.Nedospasov, S. A., see Shakhov, A. N.Nelson, P. J., see Luckow, B.Nemeth, H. E., see Lian, R. H.

XVI Author Index

Nemoto, E., see Kanaya, S.Nepom, G. T., see Gebe, J. A.Netea, M. G., Kullberg, B. J., de Jong, D.

J., Franke, B., Sprong, T., Naber, T. H. J.,Drenth, J. P. H. and Van der Meer, J. W.M. NOD2 mediates anti-inflammatory sig-nals induced by TLR2 ligands: implica-tions for Crohn’s disease. . . . . . . . . 2052

Neuberger, M. S., see Noia, J. M. D.Neuzil, J., see Erl, W.New, D. C., see Tian, Y.Ng, H., see Liu, G.Ng, K. L., see Hess, K. L.Ni, B., see Wang, L.Nibbering, P. H., see Litjens, N. H. R.Nicaise, C., see Verhasselt, V.Nicol, A. J., see Lin, H.Nieda, M., see Lin, H.Niedermann, G., see Nil, A.Nielsen, C. H., Hegedüs, L. and Leslie, R.

G. Q. Autoantibodies in autoimmune thy-roid disease promote immune complexformation with self antigens and increaseB cell and CD4+ T cell proliferation inresponse to self antigens . . . . . . . . . 263

Nikolic, T., see Geutskens, S. B.Nil, A., Firat, E., Sobek, V., Eichmann, K.

and Niedermann, G. Expression ofhousekeeping and immunoproteasomesubunit genes is differentially regulated inpositively and negatively selecting thymicstroma subsets . . . . . . . . . . . . . . . . 2681

Nimmerjahn, F., see Mautner, J.Nishimura, H., see Wen, X.Nishio, A., see Kato, T.Nitschke, L., see Zhang, J. Q.Nitzki, F., see Schlaf, G.Niu, W., see Wang, L.Noble, A., see Sawicka, E.Nocentini, G., see Ronchetti, S.Nogaki, F., see Oida, E.Noia, J. M. D. and Neuberger, M. S. Immu-

noglobulin gene conversion in chickenDT40 cells largely proceeds through anabasic site intermediate generated byexcision of the uracil produced by AID-mediated deoxycytidine deamination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 504

Nolte-‘t Hoen, E. N. M., Wagenaar-Hilbers,J. P. A., Boot, E. P. J., Lin, C.-H., Arkes-teijn, G. J. A., van Eden, W., Taams, L. S.and Wauben, M. H. M. Identification of aCD4+CD25+ T cell subset committed invivo to suppress antigen-specific T cellresponses without additional stimulation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3016

Nolte-‘t Hoen, E. N. M., Wagenaar-Hilbers,J. P. A., Peters, P. J., Gadella, B. M., vanEden, W. and Wauben, M. H. M. Uptakeof membrane molecules from T cellsendows antigen-presenting cells withnovel functional properties . . . . . . . 3115

Nolte-‘t Hoen, E. N. M., Amoroso, M. G.,Veenstra, J., Grosfeld-Stulemeyer, M.C., van Eden, W., Broeren, C. P. M. andWauben, M. H. M. Effector and regulatoryT cells derived from the same T cell clone

differ in MHC class II-peptide multimerbinding. . . . . . . . . . . . . . . . . . . . . . . 3359

Nordström, I., see Eriksson, K.Norment, A. M., see Oflazoglu, E.Nunes, J. A., see Garcon, F.Nüssler, A., see Hallatschek, W.Oak, J., see Hess, K. L.Öberg, L., Johansson, S., Michaelsson, J.,

Tomasello, E., Vivier, E., Kärre, K. andHöglund, P. Loss or mismatch of MHCclass I is sufficient to trigger NK cell-mediated rejection of resting lymphocytesin vivo – role of KARAP/DAP12-dependentand -independent pathways . . . . . . 1646

Odermatt, B., see Vollstedt, S.O’Donoghue, D. P., see O’Keeffe, J.O’Farrelly, C., see O’Keeffe, J.Offner, H., see Rich, C.Offringa, R., see Hofmann, M.Oflazoglu, E., Swart, D. A., Anders-

Bartholo, P., Jessup, H. K., Norment, A.M., Lawrence, W. A., Brasel, K., Tocker,J. E., Horan, T., Welcher, A. A. and Fitz-patrick, D. R. Paradoxical role of pro-grammed death-1 ligand 2 in Th2 immuneresponses in vitro and in a mouse asthmamodel in vivo . . . . . . . . . . . . . . . . . . 3326

Ogawa, T., see Kanaya, S.Ogun, S. A., see Hensmann, M.Oh, J.-Y., see Lee, S.-Y.Ohkubo, Y., see Seimiya, M.Ohtsuji, M., see Wen, X.Oida, E., Nogaki, F., Kobayashi, I., Kamata,

T., Ono, T., Miyawaki, S., Serikawa, T.,Yoshida, H., Kita, T. and Muso, E. Quan-titative trait loci (QTL) analysis reveals aclose linkage between the hinge regionand trimeric IgA dominancy in a high IgAstrain (HIGA) of ddY mice . . . . . . . . 2200

Oikawa, S., see Kato, T.Ojcius, D. M., see Pajot, A.Okabe, Y., see Takedatsu, H.Okada, S., see Seimiya, M.Okamoto, N., see Shimamura, M.Okamoto, S., Ji, H., Howie, D., Clarke, K.,

Gullo, C., Manning, S., Coyle, A. J. andTerhorst, C. Expression of the SH2D1Agene is regulated by a combination oftranscriptional and post-transcriptionalmechanisms . . . . . . . . . . . . . . . . . . 3176

O’Keeffe, J., Doherty, D. G., Kenna, T.,Sheahan, K., O’Donoghue, D. P., Hyland,J. M. and O’Farrelly, C. Diverse popula-tions of T cells with NK cell receptors accu-mulate in the human intestine in health andin colorectal cancer . . . . . . . . . . . . . 2110

O’Keeffe, M., see Vollstedt, S.Old, L. J., see Held, G.Oldenhove, G., see de Heusch, M.Olive, D., see Compte, E.Olive, D., see Duhen, T.Olive, D., see Garcon, F.Oliveri, M., Daga, A., Lunardi, C., Navone,

R., Millo, R. and Puccetti, A. DNase Ibehaves as a transcription factor whichmodulates Fas expression in humancells . . . . . . . . . . . . . . . . . . . . . . . . . . 273

Ono, S. J., see Arancibia-Carcamo, C. V.Ono, T., see Oida, E.Onodera, M., see Ueno, T.Oppenheim, J. J., see Chen, X.Oppezzo, P., Dumas, G., Bouvet, J.-P.,

Robello, C., Cayota, A., Pizarro, J. C.,Dighiero, G. and Pritsch, O. Somaticmutations can lead to a loss of superanti-genic and polyreactive binding . . . . 1423

Oritani, K., see Yamada, M.Ørntoft, T. F., see Vermijlen, D.Orozco, H., see Baeza, I.Orozco, H., see Hernandez-Pando, R.Osawa, H., see Arancibia-Carcamo, C. V.Osborne, B. A., see Laws, A. M.Osness, R. E., see Khoruts, A.Ostler, T., see Ehl, S.Oswald-Richter, K., Grill, S. M., Leela-

wong, M. and Unutmaz, D. HIV infectionof primary human T cells is determined bytunable thresholds of T cell activation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1705

Otte, A. P., see van Galen, J. C.Otten, L. A., see LeibundGut-Landmann,

S.Otten, L. A., see Tacchini-Cottier, F.Ottmann, O. G., see Koyama, N.Ouallet, J.-C., see von Büdingen, H.-C.O-Wang, J., see Seimiya, M.Paige, C. J., see Milne, C. D.Pajot, A., Michel, M.-L., Fazilleau, N.,

Pancre, V., Auriault, C., Ojcius, D. M.,Lemonnier, F. A. and Lone, Y.-C. Amouse model of human adaptive immunefunctions: HLA-A2.1-/HLA-DR1-trans-genic H-2 class I-/class II-knockoutmice. . . . . . . . . . . . . . . . . . . . . . . . . 3060

Pajusto, M., Ihalainen, N., Pelkonen, J.,Tarkkanen, J. and Mattila, P. S. Humanin vivo-activated CD45R0+ CD4+ T cellsare susceptible to spontaneous apoptosisthat can be inhibited by the chemokineCXCL12 and IL-2, -6, -7, and -15 . . 2771

Pakala, S. V., Bansal-Pakala, P., Halteman,B. S. and Croft, M. Prevention of diabetesin NOD mice at a late stage by targetingOX40/OX40 ligand interactions . . . . 3039

Palaniyandi, S. S., Watanabe, K., Ma, M.,Tachikawa, H., Kodama, M. and Aizawa,Y. Inhibition of mast cells by interleukin-10gene transfer contributes to protectionagainst acute myocarditis in rats . . 3508

Palazzo, R., see Fedele, G.Palfi, K., see Li-Weber, M.Palmer, R., see Adams, V. C.Pancre, V., see Pajot, A.Panina-Bordignon, P., see Mariani, M.Pantaleo, G., see Harari, A.Panzer, U. and Uguccioni, M. Prostaglandin

E2 modulates the functional responsive-ness of human monocytes to chemokines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3682

Papagno, L., see Missale, G.Pappo, O., see Wald, O.Parcellier, A., see Ghiringhelli, F.Parham, P., see Trowsdale, J.Parizot, C., see Dogan, I.

Author Index XVII

Park, H.-S., Costalonga, M., Reinhardt, R.L., Dombek, P. E., Jenkins, M. K. andCleary, P. P. Primary induction of CD4 Tcell responses in nasal associated lym-phoid tissue during group A streptococcalinfection. . . . . . . . . . . . . . . . . . . . . . 2843

Park, H.-Y., see Lee, S.-Y.Park, Y.-M., see Lee, S.-Y.Parolini, I., see Eramo, A.Partidos, C. D., Moreau, E., Chaloin, O.,

Tunis, M., Briand, J.-P., Desgranges, C.and Muller, S. A synthetic HIV-1 Tat pro-tein breaches the skin barrier and elicitsTat-neutralizing antibodies and cellularimmunity . . . . . . . . . . . . . . . . . . . . . 3723

Pascal, V., Schleinitz, N., Brunet, C., Ravet,S., Bonnet, E., Lafarge, X., Touinssi, M.,Reviron, D., Viallard, J. F., Moreau, J. F.,Dechanet-Merville, J., Blanco, P., Harle,J. R., Sampol, J., Vivier, E., Dignat-George, F. and Paul, P. Comparativeanalysis of NK cell subset distribution innormal and lymphoproliferative disease ofgranular lymphocyte conditions . . . 2930

Pascolo, S., see Probst, J.Pascolo, S., see Scheel, B.Pasero, C., see Duhen, T.Paul, P., see Andre, P.Paul, P., see Pascal, V.Payette, P., see Vollmer, J.Pecht, I., see Medgyesi, D.Pedersen, A. E., see Gad, M.Pekna, M., see Hietala, M. A.Peled, A., see Franitza, S.Peled, A., see Wald, O.Pelkonen, J., see Pajusto, M.Peng, S. L., see Lin, L.Penna, A., see Missale, G.Perillo, A., see Rutella, S.Perrin-Cocon, L., Agaugue, S., Coutant, F.,

Masurel, A., Bezzine, S., Lambeau, G.,Andre, P. and Lotteau, V. Secretoryphospholipase A2 induces dendritic cellmaturation . . . . . . . . . . . . . . . . . . . . 2293

Perrot, I., see Chaperot, L.Perschon, S., see Seidel-Guyenot, W.Persson, L., see Hietala, M. A.Peschle, C., see Eramo, A.Peters, P. J., see Nolte-‘t Hoen, E. N. M.Petersen, T. R., Bettelli, E., Sidney, J.,

Sette, A., Kuchroo, V. and Bäckström,B. T. Characterization of MHC- and TCR-binding residues of the myelin oligo-dendrocyte glycoprotein 38–51 pep-tide. . . . . . . . . . . . . . . . . . . . . . . . . . . 165

Petrovic, J., see Hall, H. T. L.Petry, F., see Cortes-Hernandez, J.Pfeffer, K., see Luckow, B.Pfeffer, K., see Vossenkämper, A.Pfeifer, G., see Averbeck, M.Pfreundschuh, M., see Held, G.Phelan, D. L., see Narayanan, K.Philpott, D. J., see Girardin, S. E.Picard, C., see Feinberg, J.Piccirillo, C. A., see Thornton, A. M.Pich, D., see Mautner, J.Pierelli, L., see Rutella, S.

Pieroni, G., see Missale, G.Pileri, P., see Masciopinto, F.Pilione, M. R., see Pishko, E. J.Pilli, M., see Missale, G.Pinheiro, S., see Missale, G.Pircher, H., see Marcolino, I.Pishko, E. J., Kirimanjeswara, G. S., Pili-

one, M. R., Gopinathan, L., Kennett, M.J. and Harvill, E. T. Antibody-mediatedbacterial clearance from the lower respira-tory tract of mice requires complementcomponent C3. . . . . . . . . . . . . . . . . . 184

Pistorio, A., see Vitale, C.Pizarro, J. C., see Oppezzo, P.Pizarro, T. T., see Reuter, B. K.Plate, T., see Jacobs, T.Pleau, J.-M., see Cotta-de-Almeida, V.Ploegh, H. L., see Gil-Torregrosa, B. C.Ploegh, H. L., see Maehr, R.Ploss, A., see Dao, T.Plumas, J., see Preynat-Seauve, O.Plumas, J., see Chaperot, L.Poinsignon, C., de Chasseval, R., Soubey-

rand, S., Moshous, D., Fischer, A.,Hache, R. J. G. and de Villartay, J.-P.Phosphorylation of Artemis followingirradiation-induced DNA damage . . 3146

Poli, G., see Rizzi, C.Poltorak, A., see Ehl, S.Pombo, A., see Kenny, E.Pons, F. G., see Hernandez, J.Pontarotti, P., see Compte, E.Pouladi, M. A., see Swirski, F. K.Powell, E. E., see Ward, S. M.Precht, P., see Seminario, M.-C.Preynat-Seauve, O., Villiers, C. L., Jour-

dan, G., Richard, M.-J., Plumas, J.,Favier, A., Marche, P. N. and Favrot, M.-C. An interaction between CD16 and CR3enhances iC3b binding to CR3 but is lostduring differentiation of monocytes intodendritic cells . . . . . . . . . . . . . . . . . . 147

Pritsch, O., see Oppezzo, P.Probst, J., Blumenthal, S. G., Tenzer, S.,

Weinschenk, T., Dittmer, J., Schoor, O.,Six, A., Rammensee, H.-G. and Pascolo,S. A conserved sequence in the mousevariable T cell receptor § recombinationsignal sequence 23-bp spacer can affectrecombination . . . . . . . . . . . . . . . . . 2179

Probst, J., see Scheel, B.Probst-Kepper, M., see Bruder, D.Proost, P., see Gijsbers, K.Proudfoot, A. E. I., see Ajuebor, M. N.Prydz, H., see Vang, T.Przybylski, G. K., see Marcolino, I.Puccetti, A., see Oliveri, M.Pulendran, B., Dillon, S., Joseph, C.,

Curiel, T., Banchereau, J. and Moha-madzadeh, M. Dendritic cells generatedin the presence of GM-CSF plus IL-15prime potent CD8+ Tc1 responses in vivo. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66

Pursch, E., see Beinhauer, B. G.Puttagunta, L., see Dery, R. E.Pyarajan, S., see Su, M. W.-C.Qiu, H., see Han, X.

Quarcoo, D., see Stock, P.Raaphorst, F. M., see van Galen, J. C.Racanelli, V., see Sansonno, D.Rachinel, N., see Mennechet, F. J. D.Rademaker, M., see Litjens, N. H. R.Radsak, M., see Hofmann, M.Radtke, F., see Tacchini-Cottier, F.Raftery, M. J., see Müller, D. B.Raine, T., see Zaccone, P.Ramdien-Murli, S., see Jeurissen, A.Ramırez, F., see Kenny, E.Rammensee, H.-G., see Dengjel, J.Rammensee, H.-G., see Hofmann, M.Rammensee, H.-G., see Probst, J.Rammensee, H.-G., see Scheel, B.Ramos, T. V., see Zhu, X.Ramsay, R. G., see Baumann, S.Rangaraj, N., see Alli, R.Raudsepp, T., see Takahashi, T.Raulet, D. H., see Andre, P.Ravensbergen, B., see Litjens, N. H. R.Ravet, S., see Pascal, V.Rawson, P., see Francavilla, V.Rawson, P., see Accapezzato, D.Rayat, G. R., see Wheat, W.Rea, D., see Litjens, N. H. R.Rechnitzer, H., see Gazit, R.Rechtsteiner, G., see Hofmann, M.Reddy, J., see Greve, B.Reen, D. J., see Kilmartin, B.Rehakova, Z., see Holtmeier, W.Reichardt, H. M., see van den Brandt, J.Reichenbach, J., see Feinberg, J.Reichert, U., see Toth, B.Reijonen, H., see Gebe, J. A.Reimann, J., see Jomantaite, I.Reimann, J., see Krajina, T.Reinecker, H.-C., see Loser, K.Reiner, S. L., see Hewitt, S. L.Reinhard, E., see Link, C.Reinhardt, R. L., see Park, H.-S.Reinherz, E. L., see Dogan, I.Reischl, U., see von Loewenich, F. D.Reiter, Y., see Held, G.Reiter, Y., see Zehn, D.Reith, W., see LeibundGut-Landmann, S.Remoli, M. E., see Coccia, E. M.Renner, C., see Held, G.Reuter, B. K. and Pizarro, T. T. Commen-

tary: The role of the IL-18 system andother members of the IL-1R/TLR super-family in innate mucosal immunity and thepathogenesis of inflammatory bowel dis-ease: friend or foe? . . . . . . . . . . . . . 2347

Reviron, D., see Pascal, V.Reynolds, H. M., see Bell, S. E.Rham, C. D., see Arlettaz, L.Riccardi, C., see Ronchetti, S.Ricci-Vitiani, L., see Eramo, A.Rich, C., Link, J. M., Zamora, A., Jacob-

sen, H., Meza-Romero, R., Offner, H.,Jones, R., Burrows, G. G., Fugger, L.and Vandenbark, A. A. Myelin oligo-dendrocyte glycoprotein-35–55 peptideinduces severe chronic experimentalautoimmune encephalomyelitis in HLA-DR2-transgenic mice. . . . . . . . . . . . 1251

XVIII Author Index

Richard, M.-J., see Preynat-Seauve, O.Richter, C., see Stassen, M.Riesen, M., see Vollstedt, S.Riol-Blanco, L., Iglesias, T., Sanchez-

Sanchez, N., de la Rosa, G., Sanchez-Ruiloba, L., Cabrera-Poch, N., Torres,A., Longo, I., Garcıa-Bordas, J., Longo,N., Tejedor, A., Sanchez-Mateos, P. andRodrıguez-Fernandez, J. L. The neuro-nal protein Kidins220 localizes in a raftcompartment at the leading edge ofmotile immature dendritic cells . . . . . 108

Ritter, G., see Held, G.Ritter, U., Meißner, A., Scheidig, C. and

Körner, H. CD8 § - and Langerin-negativedendritic cells, but not Langerhans cells,act as principal antigen-presenting cells inleishmaniasis . . . . . . . . . . . . . . . . . . 1542

Rivera, V. M., see Hong, J.Rizzi, C., Alfano, M., Bugatti, A., Camozzi,

M., Poli, G. and Rusnati, M. Inhibition ofintra- and extra-cellular Tat function andHIV expression by pertussis toxin B-oligomer. . . . . . . . . . . . . . . . . . . . . . . 530

Robbins, C. S., see Swirski, F. K.Robello, C., see Oppezzo, P.Robert, J., see Goyos, A.Roberts, L. M., see Smith, D. C.Robillard, N., see Birebent, B.Robinson, W. H., see Hueber, W.Rocha, B., see Martinic, M. M.Roda-Navarro, P., see Arce, I.Rodriguez, E., see Judkowski, V.Rodriguez, M., see Mangalam, A. K.Rodriguez, N., see da Costa, C. U. P.Rodrıguez-Fernandez, J. L., see Riol-

Blanco, L.Rodrıguez-Frade, J. M., see Carvalho-

Pinto, C.Rogy, M., see Beinhauer, B. G.Roig, M. B., see Granes, F.Rojo, J. M., see Sanchez, A.Rolink, A. G., see Tardivel, A.Röllinghoff, M., see Schleicher, U.Romagnani, C., see Vitale, M.Romagne, F., see Andre, P.Romeo, E., see Falco, M.Ronchetti, S., Zollo, O., Bruscoli, S., Agos-

tini, M., Bianchini, R., Nocentini, G.,Ayroldi, E. and Riccardi, C. Frontline:GITR, a member of the TNF receptorsuperfamily, is costimulatory to mouse Tlymphocyte subpopulations . . . . . . . 613

Rook, G., see Hernandez-Pando, R.Rook, G. A. W., see Adams, V. C.Roos, A., Xu, W., Castellano, G., Nauta, A.

J., Garred, P., Daha, M. R. and van Koo-ten, C. Mini-review: A pivotal role forinnate immunity in the clearance of apop-totic cells . . . . . . . . . . . . . . . . . . . . . . 921

Roos, A., Garred, P., Wildenberg, M. E.,Lynch, N. J., Munoz, J. R., Zuiverloon, T.C. M., Bouwman, L. H., Schlagwein, N.,van den Houten, F. C. F., Faber-Krol, M.C., Madsen, H. O., Schwaeble, W. J.,Matsushita, M., Fujita, T. and Daha, M.R. Antibody-mediated activation of the

classical pathway of complement maycompensate for mannose-binding lectindeficiency . . . . . . . . . . . . . . . . . . . . 2589

Roosnek, E., see Arlettaz, L.Rossi, A. G., see Heasman, S. J.Rossi, B., see Colantonio, L.Roth, L., see Luckow, B.Rothstein, T. L., see Tumang, J. R.Rottem, S., see Gazit, R.Rotter, V., see Herkel, J.Rouas-Freiss, N., see Le Rond, S.Rowland-Jones, S., see Hansasuta, P.Rowland-Jones, S., see Missale, G.Rowshani, A. T., Uss, A., Yong, S.-L., van

Lier, R. A. W. and ten Berge, I. J. M.Effects of CD25 monoclonal antibody onproliferative and effector functions ofalloactivated human T cells in vitro . . 882

Rudin, A., see Svensson, L.Rudin, A., see Andersson, A.-C.Rudolph, D., see Baumann, S.Rush, J. S., see Fugmann, S. D.Rusnati, M., see Rizzi, C.Russmann, S., see Baumann, R.Rutella, S., Bonanno, G., Pierelli, L., Mar-

iotti, A., Capoluongo, E., Contemi, A.M., Ameglio, F., Curti, A., de Ritis, D. G.,Voso, M. T., Perillo, A., Mancuso, S.,Scambia, G., Lemoli, R. M. and Leone,G. Granulocyte colony-stimulating factorpromotes the generation of regulatory DCthrough induction of IL-10 and IFN-§ . . . . . . . . . . . . . . . . . . . . . . . . . . . 1291

Rutgeerts, P., see Gijsbers, K.Rutz, M., Metzger, J., Gellert, T., Luppa, P.,

Lipford, G. B., Wagner, H. and Bauer, S.Toll-like receptor 9 binds single-strandedCpG-DNA in a sequence- and pH-dependent manner . . . . . . . . . . . . . 2541

Rutz, S., see de la Rosa, M.Rybtsov, S., see Shakhov, A. N.Sabat, R., see Jung, M.Sade, H., Khandre, N. S., Mathew, M. K.

and Sarin, A. The mitochondrial phase ofthe glucocorticoid-induced apoptoticresponse in thymocytes comprisessequential activation of adenine nucleo-tide transporter (ANT)-independent andANT-dependent events . . . . . . . . . . . 119

Safadi, R., see Wald, O.Saisho, H., see Seimiya, M.Sakaguchi, S., see Suri, A.Sakamoto, A., see Seimiya, M.Salaun, V., see Chaperot, L.Salerno, A., see Caccamo, N.Salerno, A., see Dieli, F.Salio, M., see Markel, G.Salio, M., see Smith, D. C.Sallai, K., see Medgyesi, D.Salmi, M., see Yegutkin, G. G.Salminen, T., see Yegutkin, G. G.Sampol, J., see Pascal, V.Sanchez, A., Feito, M. J. and Rojo, J. M.

CD46-mediated costimulation induces aTh1-biased response and enhances earlyTCR/CD3 signaling in human CD4+ T lym-phocytes . . . . . . . . . . . . . . . . . . . . . 2439

Sanchez, E., see Comalada, M.Sanchez-Mateos, P., see Riol-Blanco, L.Sanchez-Ruiloba, L., see Riol-Blanco, L.Sanchez-Sanchez, N., see Riol-Blanco, L.Sancho, D., see Caparros, E.Sanderson, C. J., see Urwin, D. L.Sanos, S. L., see Zubairi, S.Sansonno, D., Lauletta, G., De Re, V.,

Tucci, F. A., Gatti, P., Racanelli, V., Boi-occhi, M. and Dammacco, F. Intrahe-patic B cell clonal expansions and extra-hepatic manifestations of chronic HCVinfection. . . . . . . . . . . . . . . . . . . . . . . 126

Santamaria, P., see Judkowski, V.Sant’Angelo, D. B., see Dao, T.Santra, S., see McKay, P. F.Saoudi, A., see Kenny, E.Saoudi, A., see Xystrakis, E.Sargiacomo, M., see Eramo, A.Sarin, A., see Sade, H.Sarmay, G., see Medgyesi, D.Sarvetnick, N., see Judkowski, V.Sata, M., see Takedatsu, H.Sato, S., see Yanaba, K.Sato, T., Ishikawa, S., Akadegawa, K., Ito,

T., Yurino, H., Kitabatake, M., Yoney-ama, H. and Matsushima, K. Aberrant B1cell migration into the thymus results inactivation of CD4 T cells through itspotent antigen-presenting activity in thedevelopment of murine lupus . . . . . 3346

Sauberli, E., see Tardivel, A.Savino, W., see Cotta-de-Almeida, V.Savino, W., see Geutskens, S. B.Savithri, B., see Alli, R.Sawicka, E., Noble, A., Walker, C. and

Kemeny, D. M. Tc2 cells respond to solu-ble antigen in the respiratory tract andinduce lung eosinophilia and bronchialhyperresponsiveness. . . . . . . . . . . . 2599

Saylor, C., see Dao, T.Sayos, J., see Alvarez-Errico, D.Scales, H. E., Ierna, M. X., Gutierrez-

Ramos, J.-C., Coyle, A. J., Garside, P.and Lawrence, C. E. Effect of induciblecostimulator blockade on the pathologicaland protective immune responsesinduced by the gastrointestinal helminthTrichinella spiralis. . . . . . . . . . . . . . . 2854

Scambia, G., see Rutella, S.Schaper, F., see Weissenbach, M.Schatz, D. G., see Fugmann, S. D.Scheel, B., Braedel, S., Probst, J., Carra-

lot, J.-P., Wagner, H., Schild, H., Jung,G., Rammensee, H.-G. and Pascolo, S.Immunostimulating capacities of stabi-lized RNA molecules . . . . . . . . . . . . . 537

Scheffel, J., see Kirschnek, S.Scheffold, A., see de la Rosa, M.Scheidig, C., see Ritter, U.Scheinman, R. I., see Lang, J. A.Scheinman, R. I., see Wheat, W.Schenck, A., see Mayne, M.Schetter, C., see Vollmer, J.Schieferdecker, H. L., see Schlaf, G.Schild, H., see Hofmann, M.Schild, H., see Scheel, B.

Author Index XIX

Schindler, H., see Schleicher, U.Schipp, M., see Hausding, M.Schirmbeck, R., see Jomantaite, I.Schlaf, G., Nitzki, F., Heine, I., Hardeland,

R., Schieferdecker, H. L. and Götze, O.C5a anaphylatoxin as a product of com-plement activation up-regulates the com-plement inhibitory factor H in rat Kupffercells . . . . . . . . . . . . . . . . . . . . . . . . . 3257

Schlagwein, N., see Roos, A.Schleicher, U., Mattner, J., Blos, M.,

Schindler, H., Röllinghoff, M., Karaghio-soff, M., Müller, M., Werner-Felmayer,G. and Bogdan, C. Control of Leishmaniamajor in the absence of Tyk2 kinase. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 519

Schleinitz, N., see Pascal, V.Schlesier, M., see Marcolino, I.Schlöndorff, D., see Luckow, B.Schmid, W., see Baumann, S.Schmidt, C. A., see Marcolino, I.Schmitt, E., see Ghiringhelli, F.Schmitt, E., see Stassen, M.Schmitt, S., see Stassen, M.Schmitz, F., Mages, J., Heit, A., Lang, R.

and Wagner, H. Transcriptional activationinduced in macrophages by Toll-likereceptor (TLR) ligands: from expressionprofiling to a model of TLR signaling. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2863

Schneider, E., see Lisbonne, M.Schneider, G., see Chaneva, S.Schneider, P., see Tardivel, A.Schoeder, K., see Hernandez, J.Schönbein, C., see Jung, M.Schönrich, G., see Müller, D. B.Schoor, O., see Dengjel, J.Schoor, O., see Probst, J.Schott, M., see van den Brandt, J.Schrama, D., see Eggert, A. O.Schricke, C., see Ferlin, W. G.Schubart, A. S., see Mathey, E.Schulte-Mönting, J., see Ehl, S.Schumann, R. R., see Hallatschek, W.Schütt, S., see Jung, M.Schütz, G., see Baumann, S.Schwaeble, W. J., see Roos, A.Schwartz, M., see Avidan, H.Schwarz, A., see Tutsch, E.Schwarz, T., see Loser, K.Schwenger, G. T. F., see Urwin, D. L.Scorpio, D. G., see von Loewenich,

F. D.Scott, M. L., see Ye, Q.Seidel, H., see Jung, M.Seidel-Guyenot, W., Alt, R., Perschon, S.,

Knop, J. and Steinbrink, K. B cells arenot required for T cell priming in low zonetolerance to contact allergens and contacthypersensitivity . . . . . . . . . . . . . . . . 3082

Seimiya, M., Wada, A., Kawamura, K.,Sakamoto, A., Ohkubo, Y., Okada, S.,Hatano, M., Tokuhisa, T., Watanabe, T.,Saisho, H., Tagawa, M. and O-Wang, J.Impaired lymphocyte development andfunction in Clast5/Stra13/DEC1-transgenic mice . . . . . . . . . . . . . . . . 1322

Semana, G., see Birebent, B.Seminario, M.-C., Precht, P., Bunnell, S.

C., Warren, S. E., Morris, C. M., Taub, D.and Wange, R. L. PTEN permits acuteincreases in D3-phosphoinositide levelsfollowing TCR stimulation but inhibits dis-tal signaling events by reducing the basalactivity of Akt. . . . . . . . . . . . . . . . . . 3165

Senaldi, G., see Siegmund, B.Sennello, J. A., see Siegmund, B.Seo, K. H., Ko, H.-M., Choi, J. H., Jung, H.

H., Chun, Y. H., Choi, I.-W., Lee, H.-K.and Im, S.-Y. Essential role for platelet-activating factor-induced NF- ‹ B activa-tion in macrophage-derived angiogenesis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2129

Seppälä, U., see Andersson, A.-C.Sergejeva, S., see Johansson, A.-K.Serikawa, T., see Oida, E.Serre, K., see Cunningham, A. F.Setiawan, T., see Elliott, D. E.Sette, A., see Petersen, T. R.Sette, G., see Eramo, A.Setti, M., see Fogli, M.Severa, M., see Coccia, E. M.Sewalt, R. G. A. B., see van Galen, J. C.Seynaeve, C., see Vermijlen, D.Shachar, I., see Topilski, I.Shakhov, A. N., Rybtsov, S., Tumanov, A.

V., Shulenin, S., Dean, M., Kuprash, D. V.and Nedospasov, S. A. SMUCKLER/TIM4 is a distinct member of TIM familyexpressed by stromal cells of secondarylymphoid tissues and associated withlymphotoxin signaling . . . . . . . . . . . . 494

Sharpe, O., see Hueber, W.Sheahan, K., see O’Keeffe, J.Sheard, M. A., Liu, C. and Takahama, Y.

Developmental status of CD4–CD8+ andCD4+CD8– thymocytes with mediumexpression of CD3. . . . . . . . . . . . . . . . 25

Shevach, E. M., see Thornton, A. M.Shimada, S., see Matsushima, H.Shimamura, M., Kobayashi, K., Watanabe,

H., Huang, Y.-Y., Okamoto, N., Kanie,O., Goji, H. and Kobayashi, M. Genera-tion of V § 14 NKT cells in vitro from hema-topoietic precursors residing in bone mar-row and peripheral blood . . . . . . . . . 735

Shimauchi, H., see Kanaya, S.Shimizu, J., see Suri, A.Shinbori, T., Walczak, H. and Krammer, P.

H. Activated T killer cells induce apoptosisin lung epithelial cells and the release ofpro-inflammatory cytokine TNF- § . . 1762

Shirai, T., see Wen, X.Shortman, K., see Vollstedt, S.Shoukry, N. H., see Elkington, R.Shulenin, S., see Shakhov, A. N.Shultz, L. D., see Kuzin, I. I.Sidney, J., see Petersen, T. R.Sidobre, S., see Lisbonne, M.Sidobre, S., see Stenström, M.Sidobre, S., see Zaccone, P.Siegmund, B., Sennello, J. A., Lehr, H. A.,

Senaldi, G., Dinarello, C. A. and Fan-tuzzi, G. Frontline: Interferon regulatory

factor-1 as a protective gene in intestinalinflammation: role of TCR + ˇ T cells andinterleukin-18-binding protein . . . . . 2356

Siegmund, D., see Chaneva, S.Sierro, S., see Ward, S. M.Sigaux, F., see Eyquem, S.Simon, D., see Baumann, R.Simon, H.-U., see Baumann, R.Simon, J. C., see Averbeck, M.Simora, A., see Hernandez, J.Singh, B., see Bueno, C.Singh, R. R., see Karpouzas, G. A.Singh, R. R., see Yang, J.-Q.Sinkora, J., see Holtmeier, W.Sinkora, M., see Holtmeier, W.Sireci, G., see Dieli, F.Sironi, M., see Martinez, F. O.Six, A., see Amrani, Y. M.Six, A., see Probst, J.Sjöstrand, M., see Johansson, A.-K.Sköld, M., see Stenström, M.Skryabin, B. V., see Loser, K.Sleeman, J., see Averbeck, M.Slocombe, P. M., see Tian, Y.Smith, C. I. E., see Lindvall, J. M.Smith, D. C., Salio, M., Lord, J. M.,

Roberts, L. M. and Cerundolo, V. Lack ofdendritic cell maturation by the plant toxinricin . . . . . . . . . . . . . . . . . . . . . . . . . 2149

Smith, L. M., see Vieira, P. L.Smith, P. A., see Ellmerich, S.Smits, H. H., van Beelen, A. J., Hessle, C.,

Westland, R., de Jong, E., Soeteman, E.,Wold, A., Wierenga, E. A. and Kapsen-berg, M. L. Commensal Gram-negativebacteria prime human dendritic cells forenhanced IL-23 and IL-27 expression andenhanced Th1 development . . . . . . 1371

Sobek, V., see Nil, A.Sobel, R. A., see Greve, B.Soeteman, E., see Smits, H. H.Solary, E., see Ghiringhelli, F.Song, J., see Aydar, Y.Sorice, M., see Trucy, M.Sorsa, T., see Hakulinen, J.Soubeyrand, S., see Poinsignon, C.Spengler, U., see Wald, O.Spies, A. G., see Friedman, R. S.Spitzer, D., see Weissenbach, M.Sprong, T., see Netea, M. G.Stallmach, A., see Tutsch, E.Stamou, P., see Johansen, P.Stämpfli, M. R., see Swirski, F. K.Ständer, S., see Loser, K.Stassen, M., Fondel, S., Bopp, T., Richter,

C., Müller, C., Kubach, J., Becker, C.,Knop, J., Enk, A. H., Schmitt, S.,Schmitt, E. and Jonuleit, H. HumanCD25+ regulatory T cells: two subsetsdefined by the integrins § 4 g 7 or § 4 g 1 conferdistinct suppressive properties upon CD4+

T helper cells . . . . . . . . . . . . . . . . . . 1303Stassi, G., see Eramo, A.Steinbrink, K., see Seidel-Guyenot, W.Steiner, Q.-G., see Tardivel, A.Stempin, C. C., Tanos, T. B., Coso, O. A.

and Cerban, F. M. Arginase induction

XX Author Index

promotes Trypanosoma cruzi intracellularreplication in Cruzipain-treated J774 cellsthrough the activation of multiple signalingpathways . . . . . . . . . . . . . . . . . . . . . . 200

Stenström, M., Sköld, M., Ericsson, A.,Beaudoin, L., Sidobre, S., Kronenberg,M., Lehuen, A. and Cardell, S. Surfacereceptors identify mouse NK1.1+ T cellsubsets distinguished by function and Tcell receptor type. . . . . . . . . . . . . . . . . 56

Stenton, G. R., see Dery, R. E.Steuer, G., see Markel, G.Stevanovic, S., see Dengjel, J.Stierhof, Y.-D., see Su, M. W.-C.Stock, P., Kallinich, T., Akbari, O., Quar-

coo, D., Gerhold, K., Wahn, U., Umetsu,D. T. and Hamelmann, E. CD8+ T cellsregulate immune responses in a murinemodel of allergen-induced sensitizationand airway inflammation . . . . . . . . . 1817

Stockinger, B., see Johansen, P.Stokrova, J., see Draberova, L.Stolzer, A., see Dao, T.Stordeur, P., see Verhasselt, V.Storni, T., see Bachmann, M. F.Storset, A. K., Kulberg, S., Berg, I., Boy-

sen, P., Hope, J. C. and Dissen, E.NKp46 defines a subset of bovine leuko-cytes with natural killer cell characteris-tics . . . . . . . . . . . . . . . . . . . . . . . . . . . 669

Straten, P. t., see Eggert, A. O.Streilein, J. W., see Arancibia-Carcamo,

C. V.Strejan, G. H., see Bueno, C.Stren, N., see Markel, G.Strid, J., Hourihane, J., Kimber, I., Callard,

R. and Strobel, S. Disruption of the stra-tum corneum allows potent epicutaneousimmunization with protein antigens result-ing in a dominant systemic Th2 response. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2100

Strobel, S., see Strid, J.Strober, S., see Hueber, W.Stroobant, V., see Uyttenhove, C.Struck, D., see Vossenkämper, A.Struyf, S., see Gijsbers, K.Su, M. W.-C., Pyarajan, S., Chang, J.-H.,

Yu, C.-L., Jin, Y.-J., Stierhof, Y.-D., Wal-den, P. and Burakoff, S. J. Fratricide ofCD8+ cytotoxic T lymphocytes is depen-dent on cellular activation and perforin-mediated killing . . . . . . . . . . . . . . . . 2459

Su, Y.-N., see Cheng, W.-F.Su, Y.-w., Herzog, S., Lotz, M., Feldhahn,

N., Müschen, M. and Jumaa, H. Themolecular requirements for LAT-mediateddifferentiation and the role of LAT in limit-ing pre-B cell expansion . . . . . . . . . 3614

Sugimoto, Y., see Tanaka, S.Sumida, S. M., see McKay, P. F.Sun, J.-B., see Eriksson, K.Suri, A., Shimizu, J., Katz, J. D., Sakagu-

chi, S., Unanue, E. R. and Kanagawa, O.Regulation of autoimmune diabetes bynon-islet-specific T cells — a role for theglucocorticoid-induced TNF receptor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 447

Suter, M., see Vollstedt, S.Suter, T., see LeibundGut-Landmann, S.Suzuki, A., see Takedatsu, H.Suzuki, K., see Wada, H.Svejgaard, A., see Galle, P.Svenson, M., see Galle, P.Svensson, L., Rudin, A. and Wennerås, C.

Allergen extracts directly mobilize andactivate human eosinophils. . . . . . . 1744

Svensson, M., see Ericsson, A.Swain, M. G., see Ajuebor, M. N.Swart, D. A., see Oflazoglu, E.Swirski, F. K., Gajewska, B. U., Robbins, C.

S., D’Sa, A., Johnson, J. R., Pouladi, M.A., Inman, M. D. and Stämpfli, M. R. Con-comitant airway expression of granulocyte-macrophage colony-stimulating factor anddecorin, a natural inhibitor of transforminggrowth factor- g , breaks established inhala-tion tolerance . . . . . . . . . . . . . . . . . . 2375

Syrbe, U., see Kretschmer, U.Szakal, A. K., see Aydar, Y.Szondy, Z., see Toth, B.Taams, L. S., see Nolte-‘t Hoen, E. N. M.Tacchini-Cottier, F., Allenbach, C., Otten,

L. A. and Radtke, F. Notch1 expressionon T cells is not required for CD4+ T helperdifferentiation. . . . . . . . . . . . . . . . . . 1588

Tachikawa, H., see Palaniyandi, S. S.Tadevosyan, Y., see Altman, A.Tagawa, M., see Seimiya, M.Tai, T. Y., see Held, G.Takacs, K., see Ellmerich, S.Takahama, Y., see Sheard, M. A.Takahashi, I., see Yamada, M.Takahashi, K., see Tanaka, S.Takahashi, K., see Wen, X.Takahashi, T., Yawata, M., Raudsepp, T.,

Lear, T. L., Chowdhary, B. P., Antczak,D. F. and Kasahara, M. Natural killer cellreceptors in the horse: evidence for theexistence of multiple transcribed LY49genes. . . . . . . . . . . . . . . . . . . . . . . . . 773

Takase, H., see Chen, J.Takata, H., see Kobayashi, N.Takata, H., see Tomiyama, H.Takatsu, K., see Wen, X.Takeda, K., see Vossenkämper, A.Takedatsu, H., see Takedatsu, H.Takedatsu, H., Mitsuyama, K., Matsumoto,

S., Handa, K., Suzuki, A., Takedatsu, H.,Funabashi, H., Okabe, Y., Hara, T., Toyo-naga, A. and Sata, M. Interleukin-5 par-ticipates in the pathogenesis of ileitis inSAMP1/Yit mice . . . . . . . . . . . . . . . 1561

Takehara, K., see Yanaba, K.Takiguchi, M., see Kobayashi, N.Takiguchi, M., see Tomiyama, H.Takiguchi, M., see Ueno, T.Tan, G.-H., Wei, Y.-Q., Tian, L., Zhao, X.,

Yang, L., Li, J., He, Q.-M., Wu, Y., Wen,Y.-J., Yi, T., Ding, Z.-Y., Kan, B., Mao, Y.-Q., Deng, H.-X., Li, H.-L., Zhou, C.-H.,Fu, C.-H., Xiao, F. and Zhang, X.-W.Active immunotherapy of tumors with arecombinant xenogeneic endoglin as amodel antigen . . . . . . . . . . . . . . . . . 2012

Tanaka, M., see Miyasaka, K.Tanaka, S., Deai, K., Konomi, A., Takaha-

shi, K., Yamane, H., Sugimoto, Y. andIchikawa, A. Expression of L-histidinedecarboxylase in granules of elicitedmouse polymorphonuclear leukocytes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1472

Tang, Q., Boden, E. K., Henriksen, K. J.,Bour-Jordan, H., Bi, M. and Bluestone,J. A. Distinct roles of CTLA-4 and TGF- gin CD4+CD25+ regulatory T cell function. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2996

Tanos, T. B., see Stempin, C. C.Tanuma, N., see von Büdingen, H.-C.Tao, R., see Ye, Q.Tardivel, A., Tinel, A., Lens, S., Steiner, Q.-

G., Sauberli, E., Wilson, A., Mackay, F.,Rolink, A. G., Beermann, F., Tschopp, J.and Schneider, P. The anti-apoptotic fac-tor Bcl-2 can functionally substitute forthe B cell survival but not for the marginalzone B cell differentiation activity ofBAFF . . . . . . . . . . . . . . . . . . . . . . . . . 509

Tarkkanen, J., see Pajusto, M.Tascon, R. E., see Johansen, P.Tasken, K., see Vang, T.Taub, D., see Seminario, M.-C.Teeling, P., see Eldering, E.Tejedor, A., see Riol-Blanco, L.Tellam, J., see Green, K. J.ten Berge, I. J. M., see Rowshani, A. T.Tensen, C. P., see Verdijk, P.Tenzer, S., see Probst, J.Terhorst, C., see Okamoto, S.Termeer, C., see Averbeck, M.Tew, J. G., see Aydar, Y.Thananchai, H., see Hansasuta, P.Thiel, A., see Vitale, M.Thielemans, K., see de Heusch, M.Thillaye-Goldenberg, B., see de Kozak, Y.Thio, B., see Litjens, N. H. R.Thomas, J. W., see Kendall, P. L.Thomsen, A. R., see Christensen, J. E.Thomsen, A. R., see Galle, P.Thornton, A. M., Piccirillo, C. A. and She-

vach, E. M. Activation requirements forthe induction of CD4+CD25+ T cell sup-pressor function. . . . . . . . . . . . . . . . . 366

Tian, L., see Tan, G.-H.Tian, Y., New, D. C., Yung, L. Y., Allen, R. A.,

Slocombe, P. M., Twomey, B. M., Lee,M. M. K. and Wong, Y. H. Differentialchemokine activation of CC chemokinereceptor 1-regulated pathways: ligandselective activation of G § 14-coupledpathways . . . . . . . . . . . . . . . . . . . . . . 785

Tiedemann, K., see Bode, U.Tinel, A., see Tardivel, A.Ting, J. P.-Y., see Arancibia-Carcamo, C.

V.Tluk, S., see Vollmer, J.Tocker, J. E., see Oflazoglu, E.Todaro, M., see Eramo, A.Todryk, S., see Byrne, P.Toellner, K.-M., see Cunningham, A. F.Toes, R. E. M., see Hofmann, M.Tokuhisa, T., see Seimiya, M.

Author Index XXI

Tolar, P., Draberova, L., Tolarova, H. andDraber, P. Positive and negative regula-tion of Fc 4 receptor I-mediated signalingevents by Lyn kinase C-terminal tyrosinephosphorylation. . . . . . . . . . . . . . . . 1136

Tolar, P., see Draberova, L.Tolarova, H., Draberova, L., Heneberg, P.

and Draber, P. Involvement of filamentousactin in setting the threshold for degranu-lation in mast cells. . . . . . . . . . . . . . 1627

Tolarova, H., see Draberova, L.Tolarova, H., see Tolar, P.Tomasello, E., see Öberg, L.Tomiyama, H., Takata, H., Matsuda, T. and

Takiguchi, M. Phenotypic classification ofhuman CD8+ T cells reflecting their func-tion: inverse correlation between quantita-tive expression of CD27 and cytotoxiceffector function . . . . . . . . . . . . . . . . 999

Tomiyama, H., see Ueno, T.Tomiyama, Y., see Yamada, M.Tonanny, M.-B., see Lisbonne, M.Topilski, I., Flaishon, L., Naveh, Y., Harme-

lin, A., Levo, Y. and Shachar, I. The anti-inflammatory effects of 1,25-dihydro-xyvitamin D3 on Th2 cells in vivo are duein part to the control of integrin-mediatedT lymphocyte homing . . . . . . . . . . . 1068

Torres, A., see Riol-Blanco, L.Toth, B., Ludanyi, K., Kiss, I., Reichert, U.,

Michel, S., Fesüs, L. and Szondy, Z.Retinoids induce Fas(CD95) ligand cellsurface expression via RAR + and nur77 inT cells . . . . . . . . . . . . . . . . . . . . . . . . 827

Totty, N., see Laurence, A.Touinssi, M., see Pascal, V.Toyonaga, A., see Takedatsu, H.Trowsdale, J., see Mitchell, E. K.Trowsdale, J. and Parham, P. Mini-review:

Defense strategies and immunity-relatedgenes. . . . . . . . . . . . . . . . . . . . . . . . . . . 7

Troye-Blomberg, M., see Farouk, S. E.Trucy, M., Barbat, C., Sorice, M., Fischer,

A. and Mazerolles, F. CD4-induceddown-regulation of T cell adhesion to Bcells is associated with localization ofphosphatidyl inositol 3-kinase and LFA-1in distinct membrane domains . . . . 2168

Tschopp, J., see Tardivel, A.Tsurui, H., see Wen, X.Tucci, F. A., see Sansonno, D.Tumang, J. R., Hastings, W. D., Bai, C. and

Rothstein, T. L. Peritoneal and splenic B-1 cells are separable by phenotypic, func-tional, and transcriptomic characteristics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2158

Tumanov, A. V., see Shakhov, A. N.Tunis, M., see Partidos, C. D.Turner, M., see Bell, S. E.Turner, M., see Meade, J.Tutsch, E., Griesemer, D., Schwarz, A.,

Stallmach, A. and Hoth, M. Two-photonanalysis of calcium signals in T lympho-cytes of intact lamina propria from humanintestine . . . . . . . . . . . . . . . . . . . . . . 3477

Twomey, B. M., see Tian, Y.Tybulewicz, V. L. J., see Meade, J.

Tybulewicz, V. L. J. Commentary: Newinsights into the complexity of phosphat-idylinositol lipid signaling in B lympho-cytes . . . . . . . . . . . . . . . . . . . . . . . . 2964

Uchikawa, R., see Kato, T.Uckert, W., see Gladow, M.Uddman, R., see Bachar, O.Ueno, T., Fujiwara, M., Tomiyama, H., Ono-

dera, M. and Takiguchi, M. Reconstitu-tion of anti-HIV effector functions of pri-mary human CD8 T lymphocytes by trans-fer of HIV-specific § g TCR genes . . 3379

Uggeri, J., see Missale, G.Ugine, G. D., see Kuzin, I. I.Uguccioni, M., see Panzer, U.Ujiie, H., see Yamada, M.Ulanova, M., see Dery, R. E.Umetsu, D. T., see Stock, P.Unanue, E. R., see Suri, A.Unutmaz, D., see Oswald-Richter, K.Uray, K., see Medgyesi, D.Urbain, J., see de Heusch, M.Urban, J. F., see Elliott, D. E.Urbani, S., see Missale, G.Urwin, D. L., Schwenger, G. T. F., Groth, D.

M. and Sanderson, C. J. Distal regulatoryelements play an important role in regula-tion of the human IL-5 gene . . . . . . 3633

Uss, A., see Rowshani, A. T.Utz, P. J., see Hueber, W.Uyttenhove, C., Arendse, B., Stroobant, V.,

Brombacher, F. and Van Snick, J. Devel-opment of an anti-IL-12 p40 auto-vaccine:protection in experimental autoimmuneencephalomyelitis at the expense ofincreased sensitivity to infection . . . 3572

Uze, G., see Coccia, E. M.Vaage, J. T., see Helgeland, L.Vaitaitis, G. M., see Waid, D. M.Vallbracht, S., see Ehl, S.Valledor, A. F., see Comalada, M.Vallelian, F., see Harari, A.Van Assche, G., see Gijsbers, K.van Beelen, A. J., see Smits, H. H.Van Damme, J., see Gijsbers, K.van den Brandt, J., Voss, K., Schott, M.,

Hünig, T., Wolfe, M. S. and Reichardt, H.M. Inhibition of Notch signaling biases ratthymocyte development towards the NKcell lineage. . . . . . . . . . . . . . . . . . . . 1405

van den Houten, F. C. F., see Roos, A.Van der Meer, J. W. M., see Netea, M. G.van der Plas, M. J. A., see Litjens, N. H. R.van Dissel, J. T., see Litjens, N. H. R.van Eden, W., see Nolte-‘t Hoen, E. N. M.van Eijk, M., see de Vos, A. F.Van Endert, P., see Lisbonne, M.van Endert, P. M., see Lemaıtre, F.van Galen, J. C., Dukers, D. F., Giroth, C.,

Sewalt, R. G. A. B., Otte, A. P., Meijer, C.J. L. M. and Raaphorst, F. M. Distinctexpression patterns of polycomb oncop-roteins and their binding partners duringthe germinal center reaction . . . . . . 1870

van Kooten, C., see Roos, A.van Lier, R. A. W., see Eldering, E.van Lier, R. A. W., see Rowshani, A. T.

van Mierlo, G., see Ciurana, C. L. F.van Oers, M. H. J., see Eldering, E.van Riel, D., see de Vos, A. F.Van Snick, J., see Uyttenhove, C.van Veelen, P. A., see Verdijk, P.van Zuylen, W. J. M., see Green, K. J.Vandenbark, A. A., see Rich, C.Vandewalle, A., see Mennechet, F. J. D.Vang, T., Abrahamsen, H., Myklebust, S.,

Enserink, J., Prydz, H., Mustelin, T.,Amarzguioui, M. and Tasken, K. Knock-down of C-terminal Src kinase by siRNA-mediated RNA interference augments Tcell receptor signaling in mature T cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2191

Varalakshmi, C., see Alli, R.Varga, G., see Loser, K.Vargaftig, B. B., see Araujo, L. M.Vargas, A. L., see Ward, S. M.Vecchi, A., see Martinez, F. O.Veenstra, J., see Nolte-‘t Hoen, E. N. M.Velten, F. W., Duperrier, K., Bohlender, J.,

Metharom, P. and Goerdt, S. A gene sig-nature of inhibitory MHC receptors identi-fies a BDCA3+ subset of IL-10-induceddendritic cells with reduced allo-stimulatory capacity in vitro . . . . . . 2800

Vely, F., see Falco, M.Verdijk, P., van Veelen, P. A., de Ru, A. H.,

Hensbergen, P. J., Mizuno, K., Koerten,H. K., Koning, F., Tensen, C. P. andMommaas, A. M. Morphological changesduring dendritic cell maturation correlatewith cofilin activation and translocation tothe cell membrane. . . . . . . . . . . . . . . 156

Verhasselt, V., Vosters, O., Beuneu, C.,Nicaise, C., Stordeur, P. and Goldman,M. Induction of FOXP3-expressing regula-tory CD4pos T cells by human matureautologous dendritic cells . . . . . . . . . 762

Vermijlen, D., Seynaeve, C., Luo, D.,Kruhøffer, M., Eizirik, D. L., Ørntoft, T. F.and Wisse, E. High-density oligonucleo-tide array analysis reveals extensive differ-ences between freshly isolated blood andhepatic natural killer cells . . . . . . . . 2529

Vestweber, D., see Weissenbach, M.Viallard, J. F., see Pascal, V.Vieira, P. L., Wassink, L., Smith, L. M., Nam,

S., Kingsbury, G. A., Gutierrez-Ramos, J.C., Coyle, A. J., Kapsenberg, M. L. andWierenga, E. A. ICOS-mediated signalingregulates cytokine production by human Tcells and provides a unique signal to selec-tively control the clonal expansion of Th2helper cells . . . . . . . . . . . . . . . . . . . . 1282

Vigorito, E., see Bell, S. E.Viguier, M., see Lemaıtre, F.Villalba, M., see Altman, A.Villard, J., see Arlettaz, L.Villarroya, H., see de Kozak, Y.Villa-Verde, D. M. S., see Cotta-de-

Almeida, V.Villiers, C. L., see Preynat-Seauve, O.Vistica, B. P., see Chen, J.Vitale, C., Chiossone, L., Morreale, G.,

Lanino, E., Cottalasso, F., Moretti, S.,

XXII Author Index

Dini, G., Moretta, L. and Mingari, M. C.Analysis of the activating receptors andcytolytic function of human natural killercells undergoing in vivo differentiationafter allogeneic bone marrow transplanta-tion. . . . . . . . . . . . . . . . . . . . . . . . . . . 455

Vitale, C., Chiossone, L., Cantoni, C.,Morreale, G., Cottalasso, F., Moretti, S.,Pistorio, A., Haupt, R., Lanino, E., Dini,G., Moretta, L. and Mingari, M. C.The corticosteroid-induced inhibitoryeffect on NK cell function reflects down-regulation and/or dysfunction of triggeringreceptors involved in natural cytotoxicity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3028

Vitale, M., Chiesa, M. D., Carlomagno, S.,Romagnani, C., Thiel, A., Moretta, L.and Moretta, A. The small subset ofCD56brightCD16– natural killer cells is selec-tively responsible for both cell proliferationand interferon- + production upon interac-tion with dendritic cells . . . . . . . . . . 1715

Vitali, P., see Missale, G.Vivier, E., see Andre, P.Vivier, E., see Öberg, L.Vivier, E., see Pascal, V.Voegtle, D., see Amrani, Y. M.Voehringer, D., see Marcolino, I.Voigt, H., see Eggert, A. O.Volk, H.-D., see Jung, M.Vollmer, J., Weeratna, R., Payette, P., Jurk,

M., Schetter, C., Laucht, M., Wader, T.,Tluk, S., Liu, M., Davis, H. L. and Krieg,A. M. Characterization of three CpG oligo-deoxynucleotide classes with distinctimmunostimulatory activities. . . . . . . 251

Vollstedt, S., O’Keeffe, M., Odermatt, B.,Beat, R., Glanzmann, B., Riesen, M.,Shortman, K. and Suter, M. Treatment ofneonatal mice with Flt3 ligand leads tochanges in dendritic cell subpopulationsassociated with enhanced IL-12 and IFN-§ production . . . . . . . . . . . . . . . . . . 1849

von Boehmer, H., see Bruder, D.von Büdingen, H.-C., Hauser, S. L., Oual-

let, J.-C., Tanuma, N., Menge, T. andGenain, C. P. Frontline: Epitope recogni-tion on the myelin/oligodendrocyte glyco-protein differentially influences diseasephenotype and antibody effector func-tions in autoimmune demyelination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2072

von Loewenich, F. D., Scorpio, D. G.,Reischl, U., Dumler, J. S. and Bogdan,C. Frontline: Control of Anaplasma phago-cytophilum, an obligate intracellular path-ogen, in the absence of inducible nitricoxide synthase, phagocyte NADPH oxi-dase, tumor necrosis factor, Toll-likereceptor (TLR)2 and TLR4, or the TLRadaptor molecule MyD88 . . . . . . . . 1789

Voso, M. T., see Rutella, S.Voss, K., see van den Brandt, J.Vosseler, C. A., see Erl, W.Vossenkämper, A., Struck, D., Alvarado-

Esquivel, C., Went, T., Takeda, K., Akira,S., Pfeffer, K., Alber, G., Lochner, M.,

Förster, I. and Liesenfeld, O. Both IL-12and IL-18 contribute to small intestinalTh1-type immunopathology following oralinfection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite con-trol . . . . . . . . . . . . . . . . . . . . . . . . . . 3197

Vosters, O., see Verhasselt, V.Vu, N., see Birebent, B.Wada, A., see Seimiya, M.Wada, H., Matsumoto, N., Maenaka, K.,

Suzuki, K. and Yamamoto, K. The inhibi-tory NK cell receptor CD94/NKG2A andthe activating receptor CD94/NKG2C bindthe top of HLA-E through mostly sharedbut partly distinct sets of HLA-E resi-dues. . . . . . . . . . . . . . . . . . . . . . . . . . . 81

Wader, T., see Vollmer, J.Wagenaar-Hilbers, J. P. A., see Nolte-‘t

Hoen, E. N. M.Wagner, D. H., see Waid, D. M.Wagner, H., see da Costa, C. U. P.Wagner, H., see Rutz, M.Wagner, H., see Scheel, B.Wagner, H., see Schmitz, F.Wahid, F., see Ellmerich, S.Wahn, U., see Stock, P.Waid, D. M., Vaitaitis, G. M. and Wag-

ner, D. H. Peripheral CD4loCD40+ auto-aggressive T cell expansion during in-sulin-dependent diabetes mellitus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1488

Wajant, H., see Chaneva, S.Walczak, H., see Shinbori, T.Wald, H., see Wald, O.Wald, O., Pappo, O., Safadi, R., Dagan-

Berger, M., Beider, K., Wald, H., Fra-nitza, S., Weiss, I., Avniel, S., Boaz, P.,Hanna, J., Zamir, G., Eid, A., Mandel-boim, O., Spengler, U., Galun, E. andPeled, A. Involvement of the CXCL12/CXCR4 pathway in the advanced liver dis-ease that is associated with hepatitis Cvirus or hepatitis B virus . . . . . . . . . 1164

Wald, O., see Franitza, S.Waldburger, J.-M., see LeibundGut-

Landmann, S.Walden, P., see Su, M. W.-C.Walden, P., see Zehn, D.Walding, A., see Litjens, N. H. R.Waldner, H., see Ellmerich, S.Waldner, H.-P., see Greve, B.Walker, C., see Sawicka, E.Walker, C. M., see Elkington, R.Walker, S., see Elkington, R.Walmsley, S. R., see Cowburn, A. S.Walport, M. J., see Cortes-Hernandez, J.Walter, L., see Watanabe, Y.Wang, C.-R., see Yang, J.-Q.Wang, L., Wu, Y.-z., Chen, A., Zhang, J.-b.,

Yang, Z., Niu, W., Geng, M., Ni, B., Zhou,W., Zou, L.-y. and Jiang, M. MHC class I-associated presentation of exogenouspeptides is not only enhanced but alsoprolonged by linking with a C-terminalLys-Asp-Glu-Leu endoplasmic reticulumretrieval signal . . . . . . . . . . . . . . . . . 3582

Wang, L., see Ye, Q.

Wang, S., see Bilenki, L.Wang, S., see Han, X.Wange, R. L., see Seminario, M.-C.Wantia, N., see da Costa, C. U. P.Ward, S. M., Jonsson, J. R., Sierro, S.,

Clouston, A. D., Lucas, M., Vargas, A. L.,Powell, E. E. and Klenerman, P. Virus-specific CD8+ T lymphocytes within thenormal human liver . . . . . . . . . . . . . 1526

Ward, S. M., see Barnes, E.Warren, S. E., see Seminario, M.-C.Wassink, L., see Vieira, P. L.Watanabe, H., see Shimamura, M.Watanabe, K., see Palaniyandi, S. S.Watanabe, T., see Seimiya, M.Watanabe, Y., Maruoka, T., Walter, L. and

Kasahara, M. Comparative genomics ofthe Mill family: a rapidly evolving MHCclass I gene family. . . . . . . . . . . . . . 1597

Watts, C., see Hensmann, M.Watts, T. H., see Dawicki, W.Wauben, M. H. M., see Nolte-‘t Hoen, E. N.

M.Wawrousek, E. F., see Chen, J.Weber, C., see Erl, W.Weber, C., see Weissenbach, M.Weber, P. C., see Erl, W.Weekes, M., see Hansasuta, P.Weeratna, R., see Vollmer, J.Wegmann, D. R., see Wheat, W.Wei, Y.-Q., see Tan, G.-H.Weighardt, H., Jusek, G., Mages, J., Lang,

R., Hoebe, K., Beutler, B. and Holz-mann, B. Identification of a TLR4- andTRIF-dependent activation program ofdendritic cells . . . . . . . . . . . . . . . . . . 558

Weighardt, H., see Feterowski, C.Weigmann, B., see Hausding, M.Weinschenk, T., see Dengjel, J.Weinschenk, T., see Probst, J.Weinstock, J. V., see Elliott, D. E.Weiss, I., see Franitza, S.Weiss, I., see Wald, O.Weissenbach, M., Clahsen, T., Weber, C.,

Spitzer, D., Wirth, D., Vestweber, D.,Heinrich, P. C. and Schaper, F.Interleukin-6 is a direct mediator of T cellmigration. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2895

Welcher, A. A., see Oflazoglu, E.Wells, A. D., see Ye, Q.Wen, X., Zhang, D., Kikuchi, Y., Jiang, Y.,

Nakamura, K., Xiu, Y., Tsurui, H., Taka-hashi, K., Abe, M., Ohtsuji, M., Nishi-mura, H., Takatsu, K., Shirai, T. andHirose, S. Transgene-mediated hyper-expression of IL-5 inhibits autoimmunedisease but increases the risk of B cellchronic lymphocytic leukemia in a modelof murine lupus . . . . . . . . . . . . . . . . 2740

Wen, Y.-J., see Tan, G.-H.Wennerås, C., see Svensson, L.Went, T., see Vossenkämper, A.Werner-Felmayer, G., see Schleicher, U.Westendorf, A. M., see Bruder, D.Westermann, J., see Bode, U.Westland, R., see Smits, H. H.

Author Index XXIII

Wheat, W., Kupfer, R., Gutches, D. G.,Rayat, G. R., Beilke, J., Scheinman, R. I.and Wegmann, D. R. Increased NF- ‹ Bactivity in B cells and bone marrow-derived dendritic cells from NOD mice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1395

Wieczorek, G., see Luckow, B.Wiedle, G., see Legler, D. F.Wiemann, K., see Hofmann, M.Wierenga, E. A., see Smits, H. H.Wierenga, E. A., see Vieira, P. L.Wildenberg, M. E., see Roos, A.Willberg, C., see Hansasuta, P.Wilson, A., see Tardivel, A.Wilson, D. B., see Hernandez, J.Wirth, D., see Weissenbach, M.Wisse, E., see Vermijlen, D.Witter, K., see Mautner, J.Wodarz, D., see Christensen, J. E.Wolburg, H., see Engelhardt, B.Wold, A., see Smits, H. H.Wolfe, M. S., see van den Brandt, J.Wolk, K., see Jung, M.Wong, C., see Baeza, I.Wong, Y. H., see Tian, Y.Woodward, E. J., see Kendall, P. L.Wrammert, J., Källberg, E. and Leander-

son, T. Identification of a novelthioredoxin-related protein, PC-TRP,which is preferentially expressed inplasma cells. . . . . . . . . . . . . . . . . . . . 137

Wu, H., Knight, J. F. and Alexander, S. I.Regulatory gamma delta T cells in Hey-mann nephritis express an invariant V + 6/V ˇ 1 with a canonical CDR3 sequence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2322

Wu, J., see Aydar, Y.Wu, T.-C., see Cheng, W.-F.Wu, Y., see Tan, G.-H.Wu, Y.-z., see Wang, L.Wucherpfennig, K. W., see Ferlin, W. G.Wulferink, M., see Layland, L. E.Wurst, W., see Luckow, B.Wuyts, G., see Jeurissen, A.Xaus, J., see Comalada, M.Xiao, F., see Tan, G.-H.Xiu, Y., see Wen, X.Xu, R., see Han, S.Xu, W., see Roos, A.Xystrakis, E., Bernard, I., Dejean, A. S.,

Alsaati, T., Druet, P. and Saoudi, A. All-oreactive CD4 T lymphocytes responsiblefor acute and chronic graft-versus-hostdisease are contained within theCD45RChigh but not the CD45RClow sub-set . . . . . . . . . . . . . . . . . . . . . . . . . . . 408

Yamada, M., Oritani, K., Kaisho, T., Ishi-kawa, J., Yoshida, H., Takahashi, I.,Kawamoto, S., Ishida, N., Ujiie, H.,Masaie, H., Botto, M., Tomiyama, Y. andMatsuzawa, Y. Complement C1q regu-lates LPS-induced cytokine production inbone marrow-derived dendritic cells. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 221

Yamada, M., see Kato, T.Yamada, N., see Matsushima, H.

Yamamoto, K., see Wada, H.Yamane, H., see Tanaka, S.Yanaba, K., Mukaida, N., Matsushima, K.,

Murphy, P. M., Takehara, K. and Sato, S.Role of C-C chemokine receptors 1 and 5and CCL3/macrophage inflammatoryprotein-1 § in the cutaneous Arthus reac-tion: possible attenuation of their inhibi-tory effects by compensatory chemokineproduction . . . . . . . . . . . . . . . . . . . . 3553

Yang, J., see Bilenki, L.Yang, J., see Han, X.Yang, J.-Q., Chun, T., Liu, H., Hong, S., Bui,

H., Kaer, L. V., Wang, C.-R. and Singh, R.R. CD1d deficiency exacerbates inflam-matory dermatitis in MRL-lpr/lpr mice. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1723

Yang, L., see Tan, G.-H.Yang, L. and Mosmann, T. Synthesis of sev-

eral chemokines but few cytokines byprimed uncommitted precursor CD4 Tcells suggests that these cells recruitother immune cells without exerting directeffector functions. . . . . . . . . . . . . . . 1617

Yang, Q., see Lindvall, J. M.Yang, W.-C., see Garcon, F.Yang, X., see Bilenki, L.Yang, X., see Han, X.Yang, Y., see Huang, X.Yang, Z., see Wang, L.Yawata, M., see Takahashi, T.Ye, Q., Wang, L., Wells, A. D., Tao, R., Han,

R., Davidson, A., Scott, M. L. and Han-cock, W. W. BAFF binding to T cell-expressed BAFF-R costimulates T cellproliferation and alloresponses . . . . 2750

Yegutkin, G. G., Salminen, T., Koskinen, K.,Kurtis, C., McPherson, M. J., Jalkanen,S. and Salmi, M. A peptide inhibitor ofvascular adhesion protein-1 (VAP-1)blocks leukocyte–endothelium interac-tions under shear stress . . . . . . . . . 2276

Yen, T. S. B., see Masciopinto, F.Yewdell, J. W., see Chen, W.Yi, T., see Tan, G.-H.Yin, D., see Liu, G.Yin, L., see Zheng, X.Yokota, S., see Kobayashi, N.Yoneyama, H., see Sato, T.Yong, S.-L., see Rowshani, A. T.Yoshida, H., see Oida, E.Yoshida, H., see Yamada, M.Young, F. M., see Kuzin, I. I.Yousefi, S., see Baumann, R.Yu, C.-L., see Su, M. W.-C.Yu, D.-Y., see Moon, E.-Y.Yu, J. S., see Liu, G.Yuan, X., see Liu, G.Yung, L. Y., see Tian, Y.Yurino, H., see Sato, T.Zaballos, A., see Carvalho-Pinto, C.Zaccone, P., Raine, T., Sidobre, S., Kro-

nenberg, M., Mastroeni, P. and Cooke,A. Salmonella typhimurium infection haltsdevelopment of type 1 diabetes in NODmice. . . . . . . . . . . . . . . . . . . . . . . . . 3246

Zaiss, D., see Kretschmer, U.Zamir, G., see Wald, O.Zamora, A., see Rich, C.Zanetti, M., see Hernandez, J.Zang, Y. C. Q., see Hong, J.Zehn, D., Cohen, C. J., Reiter, Y. and Wal-

den, P. Extended presentation of specificMHC-peptide complexes by mature den-dritic cells compared to other types ofantigen-presenting cells . . . . . . . . . 1551

Zenclussen, A. C., Fest, S., Joachim, R.,Klapp, B. F. and Arck, P. C. Introducing amouse model for pre-eclampsia: adoptivetransfer of activated Th1 cells leads topre-eclampsia-like symptoms exclusivelyin pregnant mice . . . . . . . . . . . . . . . . 377

Zeng, D., see Hueber, W.Zerbini, A., see Missale, G.Zernecke, A., see Erl, W.Zerwes, H.-G., see Höpken, U. E.Zerwes, H.-G., see Luckow, B.Zhang, D., see Wen, X.Zhang, J. Q., Biedermann, B., Nitschke, L.

and Crocker, P. R. The murine inhibitoryreceptor mSiglec-E is expressed broadlyon cells of the innate immune systemwhereas mSiglec-F is restricted to eosino-phils . . . . . . . . . . . . . . . . . . . . . . . . . 1175

Zhang, J. Z., see Hong, J.Zhang, J.-b., see Wang, L.Zhang, X., see Han, S.Zhang, X.-W., see Tan, G.-H.Zhao, X., see Tan, G.-H.Zheng, B., see Han, S.Zheng, P., see Zheng, X.Zheng, X., Yin, L., Liu, Y. and Zheng, P.

Expression of tissue-specific autoanti-gens in the hematopoietic cells leads toactivation-induced cell death of auto-reactive T cells in the secondary lymphoidorgans . . . . . . . . . . . . . . . . . . . . . . . 3126

Zhou, C.-H., see Tan, G.-H.Zhou, W., see Wang, L.Zhu, R., see Araujo, L. M.Zhu, X., Ramos, T. V., Gras-Masse, H.,

Kaplan, B. E. and BenMohamed, L.Lipopeptide epitopes extended by an N 4 -palmitoyl-lysine moiety increase uptakeand maturation of dendritic cells through aToll-like receptor-2 pathway and trigger aTh1-dependent protective immunity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3102

Zinkernagel, R. M., see Bachmann, M. F.Zinkernagel, R. M., see Martinic, M. M.Zollo, O., see Ronchetti, S.Zou, L.-y., see Wang, L.Zubairi, S., Sanos, S. L., Hill, S. and Kaye,

P. M. Immunotherapy with OX40L-Fc oranti-CTLA-4 enhances local tissueresponses and killing of Leishmania dono-vani . . . . . . . . . . . . . . . . . . . . . . . . . 1433

Zuiverloon, T. C. M., see Roos, A.Zwart, B., see Ciurana, C. L. F.