incubators including peltier kt 115 september 2012 strictly confidential - for company use only 1...
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Incubators including Peltier KT 115 September 2012 STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY 3 1.2What is an Incubator for biological/medical applications? WIKIPEDIA: “A device used to grow and maintain microbiological cultures or cell cultures” The incubator maintains optimal growth conditions Temperature Humidity Other parameters, such as CO 2 and O 2TRANSCRIPT
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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Welcome
BINDER Incubators and the introduction of the new BINDER KT 115 with Peltier technology
NEW
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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Contents to fulfill the objective
Introduction Technical Basics Portfolio Positioning KT – KB Competition USPs Product Launch
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.2 What is an Incubatorfor biological/medical applications?
WIKIPEDIA: “A device used to grow and maintain microbiological cultures or cell cultures”
The incubator maintains optimal growth conditions
• Temperature• Humidity• Other parameters, such as CO2 and O2
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.3 TemperatureDifferent ideal temperatures for different organisms
Mammalian cells 37 °C
Bacteria Escherichia coli (intestines) 37 °C Pseudomonas (ubiquitous) 28 °C Agrobacterium (soil) 21 °C Vibrio fischeri (sea) 15 °C Thermus aquaticus 74 °C
Yeast Saccharomyces cerevisiae 30 °C
Lab temperature 20-30 °C
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.3 TemperatureDifferent ideal temperatures for different organisms
laboratorytemperature
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1.4 Incubators of different kindCool or uncool
Standard incubators Can only heat up Typical temperature range
• Minimum: 5 K to 10 K above ambient room temperature• Maximum: 60 °C to 100 °C
Typical application: bacterial incubation at 37 °C
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.5 Incubators of different kindCool or uncool
Cooling incubators Can heat up and cool down Typical temperature range
• Minimum: -5 °C to 5 °C• Maximum: 60 °C to 100 °C
Various applications• Incubation with heat input, e.g. by internal shaker• Incubation at high ambient temperatures• Incubation at 30 °C or lower
Cooling incubators with light Typical applications
• Plant growth• Insect growth• Photostability testing
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.6 Incubators of different kindCO2 or O2
CO2 Incubators Can only heat up Provide CO2 and humidity Provide O2 option Typical application: mammalian cell culture at 37 °C
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.7 Who needs Incubators?How and where to find customers
Universities and Research Institutes
Microbiology Genetics Zoology Biochemistry
Health Clinics, Hospitals Diagnostics Biomedicine Medical research Reproductive medicine Regenerative medicine
Industry Pharma Biotech Food & Beverage Cosmetics Contract research
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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1.8 Who needs Incubators?How and where to find customers
Areas Basic research Medical research Cell Biology Pharmacology Drug discovery Cell therapy In vitro fertilization (IVF) Genetic engineering
Applications Molecular biology Sterility testing Cell production Antibody production High throughput screening (HTS) Tissue engineering Model plant growth Germ identification
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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Contents to fulfill the objective
Introduction Technical Basics Incubator Portfolio Positioning KT – KB Competition USPs Product Launch
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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3.1 BINDER IncubatorsLarge portfolio
Standard incubators BD, BF
CO2 incubators C, CB
Cooling incubators KB
Cooling incubators with Peltier technology KT
Cooling incubators with light KBW, KBWF
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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3.2 BINDER IncubatorsLarge size selection: 28 different chambers
* KT 53 available end 2012
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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3.6 Common Features of BINDER IncubatorsAPT.line – Advanced Preheating Technology
Forced convection Fan-driven Chamber is surrounded by an air jacket Heat is distributed by a powerful fan Air is pulled into the preheating chamber Air is blown out horizontally
through small gaps in the side walls from both sides
Rapid heat distribution BF, KB, KT incubators
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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3.7 Common Features of BINDER IncubatorsEffective disinfection/sterilization
BINDER Incubators can heat up to at least 100 °C Providing a convenient and effective disinfection Important anti-contamination feature for microbiology
BINDER CO2 Incubators go even higher 180 °C automatic sterilization cycle Unique anti-contamination feature for serious cell culturing
180°C
100°C
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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Contents to fulfill the objective
Introduction Technical Basics Portfolio Positioning KT – KB Competition USPs Product Launch
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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2.1 Cooling TechnologyHow does vapor-compression refrigeration work?
Condenser
warm
sidehigh pressure
Waste heatChamber
Evap
orat
or
cold
sid
elo
w p
ress
ure
Cold air
Throttle Valve
refrigerantliquid
refrigerantvapor
Compressor
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Peltier element Works as a heat pump,
releasing heat on one side and absorbing heat on the other side.
Effective heat sinks are mandatory.
current flow
waste heat
cold air
– +
chamber
2.2 Cooling Technology How does thermoelectric cooling work?
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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2.7 Vapor-compression CoolingWell-known application areas
Fridge (Refrigerator) Freezer Air conditioning
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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2.8 Thermoelectric CoolingBroad application areas1
Portable cooler (e.g. camping use) Air dehumidifier CPU cooler for high-performance
computers Small laboratory instruments Diode laser Thermocycler for PCR (molecular
biology labs) Sensor cooler in digital cameras
(e.g. for astro photography) GeneAmp® PCR System 9700 from Applied Biosystems® 2
1 Wikipedia 2 products,invitrogen.com
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2.9 Peltier vs. Compressor TechnologyDistinctively different with convincing features
Advantages of the Compressor Greater heat compensation Extended temperature range to sub-zero Higher cooling-down rates High cooling efficiency
Advantages of the Peltier-Technology Safe (no flammable refrigerants) Eco-friendly (compliant to Roche K6 directive) Smaller and lighter (see right) Silent and gentle (less noise and vibrations) More robust and service-friendly Less expensive
• KB 115 Compressor (9.000 g)
• KT 115 Peltier-Chip (25 g)
• BINDER Pen (14 g)
Incubators including Peltier KT 115 September 2012STRICTLY CONFIDENTIAL - FOR COMPANY USE ONLY
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The BINDER Commitment
Best products Best services Best consulting