i xr,,...adhermy lo ihe aldndards and regulatu~~r unda !he acl. assd 11 hds reclulred lhal erceplmns...

68
This relmrl 1s requwrd by law (7 USC 2143) Fdllulr lo repo.1 Jccurdlry lo Ihe recjuIaI1011~ Call rcjull . in order lo cease aid destsl and lo be subpcl lo penalller as pfwided lor 111 Secllon 2150 See reverse slde lor lo~ler~geo,cy Rryorl Cua~lrlrl t.lo add~l~ondl ~nlorrrwltw 0180-DOA.AN ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT) - I Animal Care Program 0263 WO Th? University Of Toledo ' UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND P U N T HEALTH INSPECTION SERVICE . . Z Oct. 1, 1999 - Sept. 30, 2000 Toledo, OH-43606 3. REPORTING FAClLlN (LISI all locattons where animals were housed w used In aclual resratch. resrlng, leaching, or experlrnewtaltoru. w helo lor new purposes sherls 11 twcessary ) 1. REGISTRATION NO. I FORM APPROV 0 3 1-R-0006 OM8 NO 0579. 03 2. HaDOU i X"r,, YI wdh US04 include 2 31-Ra006. Cust Id 208 FAClLlPl LOCATIONS 1Srlosl 6 Nu~nber 01 an~mals bang bred. condllloned. ar held lor use >n leaching. 1estn8ug experlmenls research, or surgery bul rbol ye1 used l w such purposes. 1. Wolfe Hall Building /I0263 2. Universitv Hall /I5500 I hEPORT OF ANIMALS USED BY OR UNDER CONTROL OF F ( - - 3. University Hall Room iI1120J (Rats Only) -I Dogs 0 5. Cats 0 6. Gumea P~qs 0 7. Hamslers 5 8. Rabb~ls 2 9. Non-human Pr~rnales 0 10 Sheep 0 \ 11 P1qs 0 I 12 Other Farm An~mals 0 Jamaican Fruit Bats IESEARCH FACILII 3 Nurnber o l dt11111aIs uwn whtch leachmy, resedrch. experlmenls. w lesls were conducted $nvolvmgno pam, dtslress. 01 use ol pam- rehevlng drugs rAllach d~lrtlrlln~ldl .heels rl !I, 0 Nu~nkr ol dllllndh Upi)II whlch erperlrllenls. learhmg. research. surqery. or lesls were coi,ducled 18bvoIvttq accompnyong pdan or dl~lress lo Ihe Ju~rndls and lor w h ~ h apvroprule dneslhelic, a~~alges~c, ur lrd~~qu~l~zlng drugs were Used exper~menls, research surgery of tesls were conducled Itlvolvlng x:Lnmmymg patn or dwress lo Ihe dn~mals and I JI x:~~ch the use 01 appropriate meslhellc. andlgesdc ur Iranqu~l#zmg drugs would have adversely allecled !he procedures, resulls or lnlerprelallon 01 Ihe leachmg. research. experlmenls, surgery or lests (An expldnalron 01 the procedures producrng parn or drstress In lhese anrrnals and the reasons such drugs were no1 used musl be attached lo !his report) TOTAL NO OF ANIMAL, -- - - - - - - - - -- -- - - - - - - - - I ASSURANCE STATEMENTS 1 I Prulessionally acceptable standards governmy Ihe care Itealtnrrbl. and us? ol anlrn~k. l~~clud~ng dpprwlale use 01 aneslhellc. analgesc. and tranqulllllng drugs, pr1or lo, durmg and lollowll~y drlual research, leach~ng. leslmg. suryrry, or expertmentallon were lollowed by lhls research lac~l~ly Short-tail Fruit Bats 25 CONTINUED 3) Thas IaciI11y 1% . adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor and approved by he Inslolulw~uI Arbllnal &re arrt Use Cu~nm~lte. (IACUC) A sumnlay of all such exceptions IS allached t o thts annual repod. I addllmn 10 ldeitltlymg the IACUC appruved rxcrpltolls. Ihls suoltnwry lncludrs a brul ex@dndllon 01 the exCepllons. as well ds the specws and number 01 dnllrl.#lsallrcled CEl~l'lF'ICA'I'IONI%Y 1IEAI)QUAH'I'ES l<ESE~\ttCll YACII.ITY OFFICIAl. (Chief Executive Orricer or Legally 1tcaponail)le Institutional Oflicinl) I c rrllly Ihal Ilu alxwr n Irlm. r w r n l . JIKI c~w~spl~ln (7 US C 5-1 It011 2143) , / DATE SIGNED 11/28/00 APHIS FOQM 7023 m+r~ , ., vJ t1 -ht 0 . 3 KT 981 .+npo~ 5 P,,,IC I, , ikUG 91)

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Page 1: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

This relmrl 1s requwrd by law ( 7 USC 2143) Fdllulr l o repo.1 Jccurdlry l o Ihe recjuIaI1011~ Call r c ju l l . i n order l o cease a i d destsl and l o be subpc l l o penalller as p f w i d e d lor 111 Secllon 2150

See reverse slde lor lo~ler~geo,cy Rryor l Cua~lrlrl t.lo

a d d ~ l ~ o n d l ~ n l o r r r w l t w 0180-DOA.AN

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

-

I Animal Care Program 0263 WO Th? University Of Toledo '

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND P U N T HEALTH INSPECTION SERVICE

. . Z

Oct . 1, 1999 - Sept. 30, 2000 Toledo, OH-43606

3. REPORTING F A C l L l N (LISI all locattons where animals were housed w used In aclual resratch. resrlng, leaching, or experlrnewtaltoru. w helo lor new purposes sherls 11 twcessary )

1. REGISTRATION NO. I FORM APPROV 0

3 1-R-0006 O M 8 NO 0579. 03

2. H a D O U

i X"r,, YI wdh US04

include 2 31-Ra006. Cust Id 208

FAClLlPl LOCATIONS 1Srlosl

6 Nu~nber 01 an~mals b a n g bred. condllloned. ar held lor use > n leaching. 1estn8ug experlmenls research, or surgery bu l rbol ye1 used l w such purposes.

1. Wolfe Hall Building /I0263

2. Universitv Hall /I5500 I hEPORT OF ANIMALS USED BY OR UNDER CONTROL OF F

(

- -

3. University Hall Room iI1120J (Rats Only)

-I Dogs 0

5. C a t s 0

6. Gumea P~qs 0

7 . Hamslers 5

8. R a b b ~ l s 2

9. Non-human P r ~ r n a l e s 0

10 Sheep 0

\ 1 1 P1qs 0 I

12 O t h e r F a r m A n ~ m a l s 0

Jamaican Fruit Bats

IESEARCH FACILII

3 Nurnber o l dt11111aIs u w n whtch leachmy, resedrch. experlmenls. w lesls were conducted $nvolvmg no pam, dtslress. 01

use o l pam- rehevlng drugs

rAllach d~lr t l r l ln~ld l .heels rl !I ,

0 N u ~ n k r o l d l l l lndh Upi) I I

whlch erperlrllenls. learhmg. research. surqery. or lesls were coi,ducled 18bvoIvttq accompnyong pdan or d l ~ l r e s s l o Ihe Ju~rndls and lor w h ~ h apvroprule dneslhelic, a ~ ~ a l g e s ~ c , ur l r d ~ ~ q u ~ l ~ z l n g drugs were Used

exper~menls, research surgery of tesls were conducled Itlvolvlng x:Lnmmymg patn or d w r e s s l o Ihe dn~mals and I JI x : ~ ~ c h the use 01 appropriate meslhel lc . andlgesdc ur I ranqu~ l#zmg drugs would have adversely allecled !he procedures, resulls or lnlerprelallon 01 Ihe leachmg. research. experlmenls, surgery or lests (An expldnalron 01 the procedures producrng parn or drstress In lhese anrrnals a n d the reasons such drugs were no1 used m u s l be attached l o !his report)

TOTAL NO OF ANIMAL,

- -

- - - - - -

- -

--

-- - -

- - - - -

- I

ASSURANCE STATEMENTS

1 I Prulessionally acceptable standards governmy Ihe care Itealtnrrbl. and us? o l a n l r n ~ k . l ~ ~ c l u d ~ n g dpprwlale use 01 aneslhellc. analgesc. and t ranqul l l l lng drugs, pr1or lo, durmg and lo l lowl l~y dr lual research, leach~ng. leslmg. suryrry, or expertmentallon were lollowed by lhls research l a c ~ l ~ l y

Short-tail Fruit Bats 25

CONTINUED

3) Thas IaciI11y 1%. adhermy l o Ihe aldndards and r e g u l a t u ~ ~ r u n d a !he Acl. assd 11 hds reclulred lha l erceplmns l o Ihe stat~dards and regula lmm be spuul led and expla iaal by Ihe p rmctpd lnvesl~yalor and approved by he Ins lo lu lw~uI Arbllnal &re arr t Use C u ~ n m ~ l t e . (IACUC) A s u m n l a y of a l l s u c h exceptions IS a l l a c h e d t o th ts a n n u a l repod. III addllmn 10 ldeitltlymg the IACUC appruved rxcrpltol ls. Ihls suoltnwry lncludrs a b r u l ex@dndllon 01 the exCepllons. as well ds the specws and number 01 dnllrl.#ls a l l r c led

CEl~l'lF'ICA'I'ION I%Y 1IEAI)QUAH'I'ES l < E S E ~ \ t t C l l YACII.ITY OFFICIAl. (Chief Executive Orricer or Legally 1tcaponail)le Institutional Oflicinl)

I c r r l l l y Ihal Ilu alxwr n Irlm. r w r n l . JIKI c ~ w ~ s p l ~ l n (7 U S C 5-1 I t 0 1 1 2143) , /

DATE SIGNED 11/28/00 A P H I S F O Q M 7023 m + r ~ , ., v J t 1 -ht 0 . 3 K T 981 . + n p o ~ 5 P,,,IC I, ,

i k U G 9 1 )

Page 2: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

G r e a t e r Spear-Nos

CONTINUATION SHEET FOR ANNUAL REPORT OF RESEARCH FACILITY

( TYPE OH PRINT) Oct. 1,1999 - Sept . 30, 2000

Animal Care Program 0263 WO

The U n i v e r s i t y O f Toledo

Toledo, OH 43606

Hedgehogs 1 0 5 1

Egyption F r u i t

Non Covered - spec4es 1 ! ___. . I- Laboratory S t r a i n 25 7 3 2 5 0 98' - Rats , - I

- I

0

Laboratory S t r a i r 4 3 3 13 15 Mice

n

5'

Zebra F i s h 202 118 0 I

Ba t s 0

APHIS FORM 7023A (AUG P 1 )

o -

I ,

Page 3: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

5 lepor l 1s requrred by law (7 USC 2143) Failure l o reporl accordlrxj l o Ille rrgulallol ls cdll resull In an order l o cease and d e s ~ s l and l o be subjecl l o penal l~es as prov~ded lor 111 Secllorl 2150

See reverse s ~ d e lor l ~ ~ ~ w ‘ q c r , ~ y I.,~:,w~I LUC,I~L,I

addr l~or~a l rnlormallon 01 80-DOA.AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED

OMB NO 0579-0036 I ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT)

GLIATECH, INC.

23420 COMMERCE PARK ROAD

I BEACHWOOD, OH 441 22 I I

3 REPORTING FAClLllY (Llsl all localrons where anrmals were housed or used In aclual research, testing, leachlng, or exper~mer~la l ron, or held lor lhese purposes Al ldch a d d ~ l l o r ~ a l sheels 11 necessary ) I

I F A C l L l N LOCATIONS (S~les)

I Animal Facility I

1

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH F A C l L l N (Attach a t t r ~ l ~ t r o ~ ~ a l sheets 11 rlecessarv or use APHIS FORM 7023AJ ' C

2) Each pr l r lc~pal mvesllgalor has considered al ler l~al lves l o palnlul procedures

A

Anlmdls Covered By The Anlrnal

Welldre Reyula l~ons

4. Dogs

5. Cals

6. Gu~nea PIQS

7. H a m s t e r s

8. R a b b i t s

9. Non-human P r ~ r n a t e s

10. Sheep

11. Plas

12. O t h e r F a r m Anlmals

13. Oltw Animals

ASSURANCE STATEMENTS

3) T h ~ s l a c ~ l ~ l y IS adtaerlng l o Ihe slandords and r e g u l d l r o ~ , ~ under Ihe Acl. and 11 hds requrred lha l excepllons l o the standards and regulallons be s p e ~ l l l e d and explarned by the p r ~ n u p a l lnvesl~galor alkd approved by the I n s l ~ l u l ~ u ~ ~ d l Animal Care and Use Cornrnrllee (IACUC) A summary o f a l l s u c h e r c e p t l o n s I s a t t a c h e d t o l h l s annua l r e p o r t III addtlron l o ~ d e n l r l y ~ r ~ g Ihe IACUC approved PxLepllons, lhls summary lncludes a brael explar~dl lor~ o l the excepllorls. as well ds Itte speclea and number of an l l r r~ ls allecled

B Number o l animals belng bred. c o n d ~ l ~ o r ~ e d or held lor use ~n l e a c h ~ ~ g . tesllslg exper~menls. research. or surgery bul no1 ye1 used lor such purposes

1) Proless~or~ally acceplable slandords governmg Ihe care. Ireallnerrl. and use o l anrlnals. ~ n c l u d ~ n g apprortate use o l aneslhelrc, analgesrc, and tranqurhzrng drugs, prror lo, du r~ng . and l 0 l l o ~ i n g aclual research, leaching, lesling, surgery, or experlrrbenlallorl were lollowed by lhlb research lac r l~ ly

362 362

4) The ~11end1,ng Veletllbarla11 lor 111rs r e w ~ r c h lac r l~ ly has ap[vopcIa!e aulhorrly l o enswe Ihe ~IOVILIOII ot ~ d e q u a l e velerlndry Lare and l o oversee the a t l r q u x y 01 other aspeLla o l r l l t 1 1 1 1 ~ 1 cdre a ~ ~ d use

CEIWIFICA'L'ION BY 1 1 E A I ) ~ U A H ' ~ k : S RESEAKCII FACII.II'Y OP'FlCIAl. (Chief Execut ive Officer o r 1,egally 1lesponsil)le Institutional Orlicial)

I I erll ly l h ~ r Itve above 1s t r w < orrt%t and co~rlplett. ( 7 U S C Sc.1 IIOII 2143)

C Number o l dlllllldlb Upon wh'Lh leaching, research. experlnlents Or

lestS ,.,ere conducted lnvolv~ng IIO

paln dlslress, or use 01 pa111 rehevrng drugs

SIGNATURE OF C E 0 OR INSTITUTIONAL OFFICIAL

A P H I S FORM 7 0 2 3 .+ I 41 ) d t v i 1 6 I ( I( 1 6h1 * r , ~ 1 1 I\ o n ,I, I, J

[ k u G 3 1 )

ntJ

F

TOT^^ OF

( ~ 0 1 ~ c + D + E)

D Nulnber upon which experlluenls. leachmg, research. surgery or tesls were conducted ~ r rvo lv~ng accornpallylng paln or drslress l o l t ~ e a l~~rna ls and lor which approprlale aneslhellc, allalgeslc or lral,qulllzlng drugs were used

DATE SIGNED

E Number o l animals upon which leaching. experlmenls. research surgery or tesls were conducled lnvolvlng accornpanylng paln or d~slress t o the dnlmals and lor whlch Ihe use o l approprlale dneslhellc, analgesic. or lranqulllzrng drugs would have adversely dtlected the procedures, results, or mlerprelallon o l the leachtng, research. exper~menls, surgery, or lesls (An explanatron 01 the procedures producrny pern or drstress l n these anrmais a n d the reasons such drugs were not used nrust b e attached lo thts report)

Page 4: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

.his report 5 reqti,rro oy I J W 1 7 -2i 21431 F J I I U , ~ l o i e w r i jcrururny lu l r w rtguldtlo8tb C J I , See reverse sioe lor l ~ l l e r ~ q e n c , a tbor l ~ i " l l 8 i r i '"0

resull ln an order l o cease ~ n d rleslsl and lo be sublecl l o pe~~a l t tes as provided lor 8 1 8 Secllon 2150 a d d ~ l ~ o n a l l n l o r m ~ l ~ o n OI 8043OA-AN

UWTED STATES DEPARTMENT OF AGRICULTURE I. REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED

OM8 NO 0579.0036

9d wrlh USDA

ANNUAL REPORT O F RESEARCH FACILITY (TYPE 3 R PRINT)

CKILCREN'S HOSPITAL RESEARCH FOUNDATlON

700 CHILDREN'S DRIVE

COLUMBUS. OH 43205

t

3. REPORTING FACILITY ( L I ~ I all localtons where a~wna ls were housed or used In aclual fe=.rr~h, les11ftg. leachlng, or expermerbtallon, or held lor lhese purposes Allach addlllonal , %heels 11 tnrcessary )

1 FACILITY LOCATIONS (Srles)

Vivarium - lower l e v e l

I REPORT OF ANIMALS USED BY OR UNDER CONTROL (

Anmals Covered 8y The Anlrnal

Wellare Regulallons

8. Number o l anlrnals belng bred. condtlloned, or held lor use In leachlng. lesllng. experlmenls. research. or surgery but nOl yet used lor such purposes

4 Dogs

5. C a t s

6. Gu~nea P~gs

7. H a m s t e r s

8 Rabb~ts

9 Non-human P r ~ r n a t e s

10 Sheeo

1 1 P~as

12. O t h e r F a r m An~mals

C h i n c h i l l s

I ASSURANCE STATEMENTS

lESEARCH FACILITY (Attach d,/~rlttror~dl sllcels 11 rlecesSaN or use APHIS FORM 70234J '

TOTAL NO OF ANIMALS

: Number o l ~ w n a l r upon which leaching, research. experlmenls, or lesls were conducted t r~vulv~ng no pan , dlslress, or use o l paon- rellewng drugs

L I I ) Prolrsslonally acceplable slandards governing Ihe care. I real lnml, and use 01 afIlmalS, mcludmg Jpprorlale use 01 aneslhetlc. analgesic, and l ranqui lwng drugs, prlor to, dur~r tg.

and l o l l o w ~ r ~ y aclual research. leaching. lcs l~ng. surgery, or exverllruenlatlon were lnllowed by lhls research laclllly

CEI1'l'IFICA'I'ION I i Y IIEAI)QUAI<'~E:S RESEAKCIi PACII.11'Y OFPICIAI, (Chief Exccutivc Officer or Legally I tcspons ib lc lnsl i iul ional Of'licial)

I crrtt ly I ~ J I !he Jbovr IS I~Iw. I:II~II.LI. and r:wtuplt.~e ( 7 U S C S~YIKII, 2143)

D Nulnber upon which experttrtenls. leachlng, research, surgery or lesls were conducled 111volvmg xccrrpaat,:q ,za~n or dlstress l o the a~~omals and lor wh,ch approprlale aneslhellc, a,,algeslc, or lra,,qulllllng drugs were

~ DATE SIGNED

E Number o l JnlrnJlS upon w h l ~ h leaching. expenrnenls. research surgery or lests were conducled l~rvolvlng accornpdnylng paln or distress l o the amrnals and lor whtch Ihe use 01 appropnale aneslhellc. analges~c or cranqullmng drugs would have adverzelv n l l ~ c l e l !he procexjuros. ,esu!!s. o: lnlerprelallon o l Ihe leach~ng, research. experlrnents. surgery. or lesls (An explanalron of the procedures producrr~y parn or drslress In these anlmak and the reasons such drugs were no1 used ntusl be anached to lhls reporf)

Page 5: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

UNITED STATES DEPARTMENT OF AGRICULTURE I REGISTR I ANIMAL AND P L A N I HEALTH INSPECTION SERVICE YtS%%14 1 F O H M APVROVEO

O M 8 NO 0>7Q cWJ6 m

2. HEADOUARTERS RESEARCH FAClL lPl (Narna dntf Ad,lrcss. as r r . iys fw+~~l -8th USDA ,,ICIU,I,, A" 6I;'fG S t a t e U n i v e r s i t y , The

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT}

313 Reseach Foundation 1960 Kenny Road C o l d u s , OH 63210-1063 S t a t u s : A c t i v e

L FACILITY LOCATIONS tSdesl

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILIlY 1Anacn ~c l ,dr t ro t~al ;nuefs 11 ,tccrt,sarr ar irie APHIS FORM i02P. I

& B Numoer o l C Number o l 0 ,,,,,,~, E, N ~ f n b e l 01 JllllIlJlb UfJOII w h l ~ n leach~t tg, F a#>l#nals being d8t#!nals upon

rnach experttrtertls. expermtenls, research, surgery or les ls were

Ar!llndls Covered bred. wh'ch leachtng, leaching, r e s e ~ r i h cmndu~ led tf8volwng accompdny?rq pall l or dlslress

By The Anma1 comJtl~or\ed, or rese~rch , surgery, or lesls were l o the dlurnals JWJ lo1 w h c h the use 01 dppruprmte T ~ ~ A L NO

W e l l ~ r e Requ la l~o r~s held tor use an exper'mrn15, Or conducl ra ~s~vulvrng ~ n e s l h e l l c . d~~d lges l c , or lra~bqudoltng drugs would OF 4N1MALs l e ~ c h ~ ~ ~ g , leslmg. lests were

rlcLolnpanylng pJ ln or have d<lversely a l lec led Ihe procedutcs. resulls. or

rxper~rne~bls . conducled JlblresS 10 the dllllnrlis Il,lrrprelal8on 01 I he l e a c h l q . fesearch.

research, or nnvolvmg no exper!rnenls. surgery. or les ls (An explanal#on of ( ~ ~ 1 ~ . c + a,,d lo, wh,eh app,opr,ale suryery bu l no1 p a n , dlslress, 0, the procedures p r o d u o t l g palr l or dtslress ~ r r these D + E) ye1 used lor such use 01 drugs were

dnma ls ar id the reasons such drugs were not used purposes re l lev~ng drugs musl b e anached l o Ihts report)

I

4 D O ~ S 1 19 45 6 1 475

6 G u ~ r i e a Pigs 6 369 2 6 39 5

7 H a n i s t e r s 0 7 7 7 7

8 Rsbb~ts 19 405 424

9 Non-human P r ~ f n a l e s 13 4 1 54

10 Sheep 12 30 42

. 1 1 PIQS 4 39 413 85 2

12 O t h e r Farm An~mals - r F nn LOWS 1 3 V _) OW

Horses 4 115 119

Bats 0 2 8 28

Camelids 5 8 58 Chickens 100 0 100

r ASSURANCE STATEMENTS

L

I DATE SIGNED

Page 6: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

CONTINUATION S H E E T FOR ANNUAL REPORT OF RESEARCH FACILITY

r w E OR PRINT)

cl>lldlllo'l.to. 0,

f w a I W

IcJcnllhq. Ics,#ny. erwrunenl:. ,rreazr:n I,,

>uryerv bul IIIII ,el u ied lor ,,,cn w r w > e s

L

ASSURANCE STATEMENTS

110 20

110

40

6

Raccoons

Chinchillas

- Ducks

Frogs

Gerbils

Goats

2 1 0 I

I / I

APHIS FORM 7 0 2 3 A ( A U C ? 1 )

Opossums I

I

146

I

0 110

8 I 2 1 I 29 I

20 1 0 I 10

40

0

100

0

6

Page 7: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

RESEARCH FACILITY SITES LISTING

Registered Facility Name: University Laboratory Animal Resources

Registration Number: 31-R-0014

Please list below all sites that house animals under the above registration number. Be sure t o include all requested information. Do not leave any spaces blank. If the line does not apply, please mark it NIA. If you have more than three (3) sites, please copy this form as many times as needed before filling in the sites.

Site No.: 1 NamelDepartment: Postle Hall - Address: 305 W. 12th Ave. '(Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

FloorlRoom: 0089

Contact Person: ---------- --- ----------------- ------- --------- ------ ------------

Site No.: 2 NamelDepartment: Laboratory Animal Center - Address: 6089 Godown Rd. (Street Name)

Building: Buildings 1,3,4, and 6

FloorlRoom: NIA

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------

Site No.: - 3 NamelDepartment: Marion Campus

Address: 1465 M t Vernon Ave. (Street Name)

Marion OH 43302 (TownlCitv \

Building: Marrill Hall

FIoorlRoom: 390

Contact Person: ---------- -------------------- ------- --------- ------ -------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 8: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

RESEARCH FACILITY SITES LISTING

Registered Facility Name: University Laboratory Animal Resources

Registration Number: 31-R-0014

Please list below all sites that house animals under the above registration number. Be sure t o include all requested information. Do not leave any spaces blank. If the line does not apply, please mark it NIA. If you have more than three (3) sites, please copy this form as many times as needed before filling in the sites.

Site No.: 4 NamelDepartment: Graves Hall - Address: 333 W. 12th Ave. (Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

Contact Person: ---------- -------------------- ------- --------- ------ -------------------

Site No.: 5 NamelDepartment: Wisernan Hall - Address: 400 W. 12th Ave. (Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

Site No.: 6 NameIDepartment: Biological Sciences - Address: 484 W 12th Ave. (Street Name)

Cols.. OH 43210 fTownlCitv

Building: NIA

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 9: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

RESEARCH FACILITY SITES LISTING

Registered Facility Name: University Laboratory Animal Resources

Registration Number: 31 -R-0014

Please list below all sites that house animals under the above registration number. Be sure to include all requested information. Do not leave any spaces blank. I f the line does not apply, please mark it NIA. If you have more than three (3) sites, please copy this form as many times as needed before filling in the sites.

Site No.: - 7 NamelDepartment: Parks Hall

Address: 500 W 12th Ave. (Street Name)

Cols.. OH 43210 (TownlCitv

Building: NIA

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

Site No.: 8 NamelDepartment: Goss Laboratorv - Address: 1925 Coffey Rd. (Street Name)

Cols.. OH 43210 (TownlCitv I

Building: NIA

FloorlRoom: 257A and 257B

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

Site No.: 9 NamelDepartment: Sisson Hall - Address: 1900 Coffey Rd. (Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 10: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

RESEARCH FACILITY SITES LISTING

Registered Facility Name: University Laboratory Animal Resources

Registration Number: 31-R-0014

Please list below all sites that house animals under the above registration number. Be sure to include all requested information. Do not leave any spaces blank. If the line does not apply, please mark it NIA. If you have more than three (3) sites, please copy this form as many times as needed before filling in the sites.

Site No.: - 10 NamelDepartment: Veterinary Hospital

Address: 601 Tharp Street (Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

FloorlRoom: 01 26

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

Site No.: I I NamelDepartment: Ohio Agriculture Research and Development Center - Address: 1680 Madison Ave. (Street Name)

Wooster, OH 44691 (TownlCity )

build in^: NIA

FloorlRoom: NIA

Contact Person: -------- ---- ------ ------- --------- ------ -------------------

Site No.: - 12 NamelDepartment: Botany and Zoology

Address: 1735 Neil Ave. (Street Name)

Cols., OH 43210 (TownlCity )

Building: NIA

FloorlRoom: 181

Contact Person: ---------- --- ----------------- ------- --------- ------ -------------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 11: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

F F ~ u i 1 d i n . r 6th f loor ! N C B m l A l n o . .

See reverse s ~ d e lor Thls reporl IS requ~red by law (7 USC 2143) Fa~lure l o report according t o Ihe regulallons can result an order 10 cease and deslsl and l o be subject l o pertallles as p rov~ded lor 111 Secllon 2150 addltlonal lnlormallon 01 80 DOA AN

Animals Covered By The Arr~mal

Wellare Reyulat~ons

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

. . 3

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

onmals bemg bred, cond~lioned, or held lor use In leachmg, lesttng experlments, research. or surgery but no1 ye1 used lor such purposes.

1 REGISTRATION NO. I FORM APPROVED

31-R-001': OMB NO 0579-0036

2. HEADOUARTERS RESEARCH FAC!LITY (Name a n d Address. as reyrslered wrth US04 tnclude Zrp Cr

31-R-0017, Cust I d 223

CLEVELAND CLINIC FOUNDATION

9500 EUCLID A V E

CLEVELAND. OH 44195

3 REPORTING FACILITY (List all locattons where anrmals were housed or used In a ~ t u a l researLh, lesllng, lea ~ d d l l l o n a l

sheets 11 tieLessary )

FACILITY LOCATIONS (Srtes)

I

1 ASSURANCE STATEMENTS

4 Dogs

3 Cats

6 Gu~nea P~gs

7 H a m s t e r s

8 R a b b t t s

9 Non-human P r ~ m a t e s

10 Sheep

11 Plus

12 O t h e r F a r m An~mals

8

3

0

0

0

0

3

11

I 1) Proless~onally acceptable standards governtng Ihe care. Irealtnent. and use o l anlmals, rnclud~ng approrule use 01 aneslhetlc, analgeslc, and t ranqu~ l~z lng drugs, prtor lo , du r l r~g

and lollowlng actual research, teaching, lestlng, surgery, or experlnterllallorl were lollowed by lhlh resear~h faclllly

L Buildina 1st. f loor

Calves 0

13 O l h e r An~mals

Goats 0

2) Each pr~rficlpal ~rivesllgalor has considered allerlbalrves l o palnlul procedures

Off Site F a d i t v ( H i r a m , OH )

3) Thrs l d ~ ~ l ~ t y IS adhermg t o the standards and r e g t i l a l ~ ~ ~ t s under Ihe ALI and 11 has requored that excepl~ons l o the slandards and regulal~ons be s p e ~ ~ l ~ e d and explawed by the pr~nc pal ~ n v e s l ~ g a l o r and approved by the I n s l ~ t ~ ~ l ~ u ~ k ~ l Anlmal Care and Use Cutnmlttee (IACUC) A sumnlary o l a l l s u c h excep t lons I s a l t a c h e d t o l h l s annua l r e p o r l 111

addr l~on l o ~denl l ly lng Ihe IACUC approved PXLepImtis, lhls sulwrnary IIICIU~BS a brref explanal~on 01 the exceplluns. as well as the spectes and number o l animals allected

4) Thc dl le l tdt tq velerlrbarldn Iur Ihls reserlrch Iacll l ly has ap()luprlale authorl ly 10 ensure the provlsloll o l adequale velerlnary care and l o oversee the aclequacy o l other aspcclb o l a1811rtdl core a r ~ d use

CERTIPICA'I'ION IIY 1iEAI)QUAHTES HESEAHCII E'ACI1,II'Y OFE'ICIAI. (Chief Executive Officer or Legally l lespons ib le lnsl i iutional Ol l ic ia l )

I c r r l l l y lhal l l le aLx1ve is Irua, l:orrl!Lt. and cwrlplele (7 U S C Stn:llnn 2143)

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Altach a ~ l r r l i l ~ n r ~ a l shcels 11 tlocessary or use APHIS FORM 70234) '

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL I DATE SIGNED

I

F.

TOTAL NO OF A ~ l ~ A ~ s

( ~ 0 1 ~ . c + D + E)

A 1 B Number of

1

-

- -

-

-

-

-

-

-

-

-

- - -

- -

-

-

-

-

E. Numbel o l an~rnals upon whlch teachrng. experiments, research, surgery or tests were co~rducled Involving accompanying pa111 or d~s l ress to Ihe anrmals and lor whrch the use o l approprtale aneslhetlc, analgeslc, or lranqulllzrng drugs would hove adversely alfected the procedures, results, or in lerprela l~on o l the teachmg, research, exper~ments, surgery, or tests (An explanatton of the procedures producrng parn or distress l n these antmals and the reasons such drugs were not used nws t b e attached to this reporl)

C N u ~ i ~ b e r of a ~ l ~ l r m l s upon whlch lea~h l r lg , research. experiments, Or

lests were conducted IIIV~IVIII~ no parn, dlslress, or use o l p a ~ n - rellevlng drugs

- -

t

D Nulnber a,llmalh whlch exper6111enls. teachlng, research, surgery, or lests were corrducled ~nvulvrng accompa~ iyng paan or d~stress l o Ihe alllmals arid lor wh,ch approprlJte arreslhetlc, allalgeslc, or Ira,,qulllztng drugs were used

Page 12: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

T h ~ s reporl 1s requ~red by law (7 IJSC 21431 Falure l o report according l o the regulal~ons can See reverse s ~ d e lor

result on an order to cease and des~s l and l o be r u b ~ e c l l o penallres as p rov~ded lor III Section 2150 addlllonal l n lo rmd l~on 01 80-DOA AN

IAMS COMPANY, THE

7250 POE AVENUE

DAYTON, OH 45414

-- UNITED STATES DEPARTMENT OF AGRICULTURE

AYIMAL AND PLANT HEALTH INSPECTION SERVICE

. .. . >

I

3. REPORTING FAClLlrY (Lest all locations where an~mals were housed or used In actual research, lestlrlg, le,,maoy, ". srrr .,,., SIIIU,IV.I, ..C.U ..,. ,..La.- pYIFALa -,..Ic~ add111011al

st~eels II ~~ecessary ) I

1 REGISTRATION NO. I FORM APPROVE

31-R-0018 OMB NO 0~79.0036

2. HEADOUARCPC DCCCAPPU F A r l l IN lNnmn and Addrecc ac rarrlr larad wrth U S 0 4 lnclude L p

21 1

I I FAClLlrY LOCATIONS (Srtes)

I See Attached

I

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach d ~ l t d r t ~ n t ~ d l sheets r l ,leLc.ssdry or use APHIS FORM 7023A) '

9. Non-human P r ~ m a t e s

10. Sheep

. 11. P~as

12. O t h e r F a r m Anlmals

13. O t h e r An~mals

ASSURANCE STATEMENTS

4. ~ o g s

5. C a t s

6. Gu~nea P~gs

7. H a m s t e r s

8. R a b b t t s

1) Prolws~onal ly acceptable slaridards governing the care, Irealment, and use o l anlmals. tnclud~ng apprormle use o l anesthellc, analyes~c, and tranqull lrrng drugs, prlor lo, durmg. and lollowlng actual research, leaching. losting, surgery, or experlmenli l l~on were lnllowed by t h ~ s research Iac~l l ly .

F

TOTAL OF A N ~ M A L ~

(c& c + D + E)

A

Anlmdls Covered By The Anrmai

Wellare Regulallons

2) Each pr~nclpal Invesllgalor has consrdered allernallves l o palnlul procedures

2 2

9

3) Thrs lac~lr ly IS adtterlng l o the standards and regulalrol~s under the Act. and 11 has requ~red that exceptlolls to the s lmdards and regulations be s p e d l e d and explained by the p r l n ~ l p ~ l ~nves l~ga lo r and approved by the I n s t ~ t ~ ~ t l o t ~ a l Anma1 Care and Use Co lnm~l lee (IACUC) A Summary o f a l l s u c h excep t tons I s a t t a c h e d t o t h l s annua l r e p o r t 111

addll lon l o ~dentl lylrtg Ihe IACUC approved Pxcepllnns, lhls hulrlmary Irk3udes a b r ~ e l explanallon of the exceptions. as well as l l le specles and number o l dnllnals allected

B Number 01 anmals b e ~ n y bred cord l t~oned or held lor use !n leachlng teslmg exper~me~rts. resear~h or surgery bu l not yet used tor such purposes

4) The dlterldlllg veterlnarldII lor Itllh resedlch l a ~ l l l t y has aPlJrUprlale aulhur~ly l o erlsuie lhe provlsloll o l adequate velerlrlary Lare and to oversee the ~ d e q u a c y o l other aspecls o l dtmnal cdre a81d use

113

207

CEKTIFICA'I'ION HY IIEA1)QUAH'I'ES IIESEAKCIf FACII.11'Y OFFICIAI. (Chief Executive Off icer o r Legally Ileaponsiblc Inatilutional Official)

I 1erl11y that the abuve 15 tlrle, correcl. J I I~ ~ ~ m p l e l e (7 U S C Sw 11011 2143)

SIGNATURE OF C E 0 OR INSTITUTIONAL OFFICIAL

E Number o l an~mals upon w h ~ h leachtng. expertments research surgery or lests were conducled lnvolvlng accomparlyrrlg paln or dlslresh l o the animals and lor whlch the use o l approprlate Jneslhetlc, analgesic, or I ranqu~l lz lng drugs would have adversely allected the procedures, results, or lnlerprelatron of the leachmg, research. experiments, surgery or lests (An explanatron 01 the procedures producrrly parn or drstress rn these anrmals a n d the reasons such drugs were no1 used n ~ u s t be attached l o lhrs report)

C Number o l anlrnals upon

tearhlnga research. experlmenls Or

tests were conducled ~ n v o l v ~ n g no Pam dlslress or use of pa lw reltevmg drugs

2 7

28

D Number upon w h ~ c h experunents. Ieachmg. research surgery or lesls were conducled mvolvtng accompanying paln or d~stress to Ihe a ~ ~ l m a l s and lor which approprlale aneslhellc, allalgeslc, or trarlqulllllng drugs were used

0

0

140

235

Page 13: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

FACILIIY SITES LISTING

Licensee/Regis t rant Name: Paul F. rams Technical Centei

License/Regis t ra t ion Number: 31-R-018 -

Please l i .s t below a l l s i t e s t h a t house animals under the above reg i s t ra r ion numoer. ae su re t o include a l l requested infornat ion. Do not leave any spaczs blank. I f the l i n e does no t apply, please mark i t N / A . I f you have more than three (3) s i t e s , p l e a s e couy t h i s f o r m . a s many times as needed before f i l l i n a in the s i t e s . -

S i t e No.: -- Narne/Uepartment: . h i m a 1 Care Center

Address: paul F. Iams Technical Center 6571 State Route 503 North PO Box 189 T , e w i s h ~ p . OH 6 5 3 53-07 8 9

Contact Person: ----- ------- -------- ----- ------- - - - - - - - - - - - -

S i t e No.: - Narne/Department:

Address :

Building:. - .

Contact Person: Phone No. :

S i t e No.: - Narne/Department:

Address :

Building:

Contact Person: Phone No. :

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 14: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Animal Research Laboratory

3s requrred by law (7 USC 2143) Fa~lure l o report accordrr~y l o I l ~ e r e g u l a l ~ o ~ ~ s call See reverse slde lor I ~ k I ~ r c l y t ' t i ~ y tit pur l LUIII

order l o cease a:d d e s s l and l o be subjecl l o penalt~es as provlded lor III Secllon 2150 addrllonal rn lormdl~on 0 180-DOA AN

REPORT OF ANIMALS USED BY

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

..

Anrmals Covered By The Anlmal

Welfare Regulaltons

I REGISTRATION NO I FORM APPROVED OM6 NO 0579-0036 I

2. HEADOUAi wfth US04 rnclude 31-R-0023, Cust Id 230

GOOD SAMARITAN HOSPITAL DEPT OF MEDICAL RESEARCH

375 DIXMYTH AVENUE

CINCINNATI. OH 45220

4. Dogs

5. C a t s

6. Gu~nea P~gs

7. H a m s t e r s

8. R a b b l t s

9 Non-human P r ~ m a t e s

lo. Sheep

, 11. PIQS

12 O t h e r F a r m An~mals

Goats

3 REPORTING FACILITY (Last all locations where anlmals were housed or used In actual resedrch, lesllng, leach~ng, or exper~merr ta l ro~~ or held lor lhese purposes Al lach add~lronal

shecls 11 rrecessary )

FACILITY LOCATIONS (S~les)

I

13. O t h e r Anmals

I ASSURANCE STATEMENTS

UNDER CONTROL C

B Number 01 arrlrnals berng bred. condrl~oned, or held lor use In lea~hrng , lesllng. expermenls. research, or surgery but no1 yet used lor such purposes

RESEARCH FAClLlT

C Nurr~ber of JIIIII~J~~ upon whrch learhmg. research. experllnenls, or lests were conducted lrrvolvrng no paln, dstress, or use 01 P~III- rellevrng drugs

I ach ddrdftfor~al sheets 11 r1et

Nu~nber u l dt~rrnals up or^

whlch experllrlenls. l e a ~ h ~ n g , research. surgery, or IeSlS were conducted lnvulvrng accornpanylng paln or drhlress l o Ihe alrrmals and lor whrch approprrale aneslhelrc, a~lalgeslc, or trar~qull lzlng drugs were used

- -

zessary or use APHIS FORM 7023A) '

E. Number o l anlrnals upon whlch leachmg, expertments, research, surgery or tesls were conducled rnvolvlng accompdnylng paln or dlslress l o Ihe anrmals and lor whrch Ihe use 01 approprlale dnesthellc, andlgeslc, or lranqull lzlng drugs would have adversely af lec led Ihe procedures, results, or Interpretallon 01 the teachmg, research. expertments, surgery, or tesls (An explanatron 01 the procedures producrny p a ~ n or d~stress rn these anfmals a n d the reasons such drugs were not used nws t be anached to thrs report)

TOTAL NO OF ANIMALS

I 1) Prolesslonally acceptable slandards governmg the care, trealmenl. and use o l anlrndls. Inc lud~ng dpprorrale use 01 anesthellc, analges~c, and tranqurl lany drugs, p r ~ o r lo, durrrlg.

and lollowlrly aclual research, leach~ng, lesllng, suryery, or experrnlenlallorl were lollowed by thrs resedrch lac~ l r l y

2) Each pr l r~clpal Inveslrgalor has cona~dered allernallves l o pamlul procedures

3) Thls Id~111ty IS adhermy t o Ihe sldlldards and r e g u l a t ~ o ~ ~ s under Ihe Act, and 11 hds requrred lhal exceptrons l o lhe standards and regulallons be spe~r l led and explamed by Ihe prrnc.~pdI ~nveslrgalor and approved by Ihe Jr~slrlt~trorral Anr~naI Cdre a r ~ d Use Cornrn~llee (IACUC) A summary o f a l l s u c h e r c e p t l o n s 1s a t t a c h e d t o l h l s annua l report In addrlron l o rdenl l ly~ng Ihe IACUC.dl~proved Pxcepllons l h ~ s summary Includes d brlel e x p l d ~ ~ d l ~ o n 01 the e x c e p ~ ~ o ~ ~ s . as well ds the specles and number ot dn~rndls dllecled

4) The ~1 te ld11 ,g velerlltarlat~ lor Ihls research Iac~lr ly has approptldle ~ u l h o r r l y l o ensure Ihe provlslotl o l adequale veterrnary w r e and l o oversee the adequscy o l other s s p ~ c l h (11 JILIIIIJI care a81d use.

CE:KI'IFICA'I'ION BY I1EAI)QUAK'~ES 1tESEAIICII FACI1,II'Y OFFICIAI. (Chief Executive Officer or Legally Itesponsible Institutional Official)

I c:erlrly lhal Itbe above is true. cn r rw t , did complele (7 U S C 6 ? ~ 1 r o n 2143)

SIG

10/23/00 A P H I S FORM 7073 M S , ) I , ,~ ,., v:, I OP<L! ir, .'", 1!.)',1 88 * r , ( t~ tC, , I , . , I , ! ,

i ALJG 9 1 )

DATE SIGNED

Page 15: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

See reverse s ~ d e lor Thls report IS required by law (7 USC 2143) Fa~lure l o reporl according to lhe regufatlolls Call addll lonal lrllormatlon 0180 M A AN

, resull lh an Order to cease a!ld deslsl and l o be sublect to pellalt~es as provlded lor 111 Secllon 2150

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. I FORM APPROVED ANIMAL AND PLANT HEALTH INSPECTION SERVICE O M 8 NO 0579 0036 I

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

I ' wrlh US04 1

BOWLING GREEN STATE UNIVERSITY

120 MCFALL CENTER

BOWLING GREEN, OH 43403

I

3 REPORTING FAClLllY (Llsl all local~ons where animals were housed or used In aclual research, leslong, teachlng, or experlmelbtallon, or held lor these purposes sheets 11 wcessary )

1 I FAClLllY LOCATIONS (SlleJ

Bowling Green State University Life Science Annex

I REPORT OF ANIMALS USED BY OR UNDER I

CONTROL

A

Anlmdls Covered By The An~mal

Wellare Reyula l~ons

B Number o l animals bemg bred. cond~ l~oned , or held lor use ~n leach~ng, les01bg. expertmellls, research. or surgery but not yet used lor such purposes

4. Dogs 0

5. Cats 0

6. Gu~nea Pigs 0

7. H a m s t e r s 0

8 R a b b ~ t s 8

9. Non-human P r m a t e s 0

10. Sheep 0

. 11. P~as 0

12 O t h e r Farm Anmals 0

OF RESEARCH FACILITY (AHdch ddrrlrlror~dl sheds 11 rlecessdn, or use APHIS FORM 7023A) '

I I ASSURANCE STATEMENTS

1) Proless~onally acceptable standards governmy Itbe care. Ireatrnenl. dnd use 01 anlmdts. ~ n c l u d ~ n y dpprorldle use o l dnesthetlc, analgeslc, and tranqulllzlrlg drugs, prtor lo, durlrlg. and to l low~ng aclual research, teachmg, testlny surgery, or experlrnentatlon were followed by this resear~h lac l l~ ty

2) Each pr~nclpal lnvestlgalor has collsldered alternallves to pa l~ l tu l procedures

F

TOTAL NO OF A N ~ M A L ~

(COIS C + D + E)

C Number o l anlrnals upon which teaching, research, experln'ents Or

tests were conducled ~ n v o l v ~ n g IIO

pan , d~slress or use o l pam. rellevlny drugs

3) Th~s I~LIIIIY IS adhering t o the slandards a~ad r e g u t a t ~ o ~ ~ s under the Act. and 11 has requ~red lhat exceptions t o the slandards and regulations be specltred and explamed by the pr~nc.lpaI Invesllgalor and approved by the Ins t l t~ l l l o l~a l Anllnal Care and Use Cotnlnlllee (IACUCI A summary o f a l l s u c h excep t tons IS a t t a c h e d t o th l s annua l r e p o r t In addll lon l o ~ d e n t ~ t y ~ r ~ g Ihe IACUC a l~proved Pxcepllons, lhls summary Includes d brlel exp ld l~d t~on o l the excepllotls, as well as the specles and numbel o l a n ~ ~ ~ ~ a l s a l lec led

4) Tile d l l e r ~ d ~ c ~ g velerllidrldll to1 Ihlb research l a ~ l l l t y has appwp#late aulhorl ly l o ensule Ihc provtslon o l adequate velerlnary care and l o oversee lhe adequacy u l other aspccla nl ~IIIIIIJ~ care astd use

D Number a,lllnal, uporl w h ~ h experurlenls. teach~ng. research. surgery, or tests were conducted ~ ~ ~ v o l v ~ n g accompa~lylng pdln or dlslrcss to the JIII~JIS and ,or which appropriate anesthetic, arlalgeslc, or lrallqulllrlng drugs were used

E Number o l an~mals upon w h ~ h leach~ny. experiments, research, surgery or tests were co l~duc led ~nvolv lny accompanylny paw or d~slress to the a ~ ! ~ m o l s and for whlch Ihe use o l approprlale anesthetlc. analgeslc, or l ranqu~l lz lng drugs would have adversely allected the procedures results or Inletpretatlon of the teaching, research. expen~nenls, surgery, or lests (An explanahon of the procedures produc1r)y pan or distress ~n these anrrnals a n d the reasons such drugs were no1 used nrusl be affached to thrs report)

I APHIS F O R M 7073 -,s ,, 8 J , ! , ,Iat.! :?, , ", (3C.l h f i , * t , $ , , I ,<, ,)r,,,,,l, 1, . 1

I L iJG iil I

CER'I'IE'ICA'I'ION BY 1IEAI)QUAHTES ItESEAKCIl FACII.II'Y OFPICIAI,

DATE SIGNED

/ . / / l / / / / / / 3

Page 16: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Thls report 1s r e q u ~ ~ e d b y law ( I USC 2143) Failure lo feporl accordll ly l o lhe regulallolls Call See reverse s ~ d e lor IIIIC r d g ~ a L Y N t /,011 LOII I~UI 1 4 0

resull In an order to cease and deslsl and l o be sublecl l o p e ~ ~ a l t ~ e s as provlded lor 111 Secllon 2150 addll lonal l r i l o rm~ l lon 0 180 DOA AN

\

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. I FORM APPROVE ANIMAL AND PLANT HEALTH INSPECTION SERVICE OM8 NO 0579.0036

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

. .

UNIVERSIlY OF CINCINNATI

RESEARCH 8 ADVANCED STUDIES P.O. BOX 210627

I HEADOUARI'-- ----. --.. -.-" .-' ' wrlh US04 include t p 31-R-0027, Cust Id 233

I CINCINNATI. OH 45221 - 3. REPORTING FACILITY (LISI all localions where anmals were housed or used In actual restlarch. tesllrig, leacnlng, or e x p e r ~ m e n l a l ~ o ~ ~ , or held tor lhese purposes. Al lach addltlonal

sheets 11 rlecessary )

I I

FACILITY LOCATIONS ISltesl

1

I A

Anlrnals Covered By The Anlmal

Welfare Reyulallons

Medical S c i e n c e s B u i l d i n g , French B u i l d i n g ,

Number of anlmals bemg

I n s t i t u t e f o r Environmental H e a l t h ,

bred, condllloned. or held lor use In leachmg, leslmg. experimenls. research. or surgery bul no1 ye! used lor such purposes

Card iovascu la r C e n t e r , West Campus F a c i l i t i e 1 REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (AHdch ddltfrtrnrld/ sheds 11 rlcressdry or l i re APHIS FORM 702%)

'

C Number 01 Nu,nber al,llnafs upon E Number o l anln~als upon w h ~ h teachlng F a ~ ~ i ~ a l s upon whlch experltrlenls. experiments, research surgery or les ls were which learhlr'g, tearhdng research. conducled l ~ ~ v o l v ~ n g accornp.lrlytrry paln or dlslress research, surgery or lesls were

l o !he animals and lor whlch !he use o l appropriate TOTAL NO experlmenls Or conducted ~l ivolv lng dneslhellc, analgesic, or tranqulllzlng drugs Would OF ANIMALS 1esIs were accompanymy p a n or have adversely s l lec led Ihe procedures resulls, or conducted d~stress 10 Il le awmals lnterprelatlon o l the leach~ng. research l ~ i v o l v ~ n g 110 and lo, which approprlale experlrnenls, surgery, or tests (An e w l a n a l ~ o n of (Cobs C + paln d~slress or anesthetic allalgeslc, or

the procedures producrny parn or drstress rn these D + E) use of paon- drugs were

an~mals a n d the reasons such drugs were not used

rehevmy drugs nws t b e anached l o fhrs report)

4 Dogs

5 C a t s

6. Gumea P ~ g s

7. Hamsters

8. R a b b ~ t s

9. Non-human P r ~ m a l e s

10. Sheep

11. PIOS

12. O t h e r Farm An~mals

1 4 4 0 45

1 ) Proless~or~ally acceptable slandards governmg the care, treatrnrnl, and use 01 anlmals, mcludmg approrlale use o l anesthetic, analgeslc, and l r a n q u ~ l ~ r m g drugs, prlor to, dur l r~g. and lo l l ow~ng aclual research, leachmy, leslmg, suryery, or experorrbenlaltorl were tollowed by Ihls research lacihly

3 8

36 7

2 5

0

0

17

0

154 gerb i : - s

2) Each pr~tdclpal mvesllgalor has considered allerlmllves l o p a n ~ l u l procedures

3) T h ~ s IJLIIII~ IS adhermy 10 Ihe stdtidards and r e g u l a t w ~ s under the Acl and 11 has requ~red thal excepllons l o Ihe slandards and regulations be spectlled and explained by Ihe prmc ,pal ~ r i ves l~ga lo r aud approved by the I n s t ~ t t r l ~ o ~ ~ ~ l Anomdl Care and Use Comml lee (IACUCI A sumnlary o l a l l s u c h e r c e p t l o n s 1s a l t a c h e d l o l h l s annua l r e p o r l In addlllon l o odenl l ly~r~g the IACUC approved r x ~ e p l m n s Ihls sulnmary Includes a brlel exp la~~a l lon 01 lhe exceplloas, as well as Ihe specles and number o l anlrrlals J l l e ~ l e d

4 1

7 3 7

183

0

2 9

147

2 c a l v e s

32 g e r b i l 0

4) Tim d l l e ~ d l ~ i g Velerl l iJrldl~ lor lhls resedrch Iao l l l y has approptlale dulhorl ly l o elbsule Ihc provlsloll o l adcquale veterlllary care arid l o oversee the adequacy 01 olher aspecls o l ~IIIIIWI care a~bd use

186 ger

CEH'I'IFICA'I'ION BY 1IEAI)QUAH'l'ES RESEAHCIi PACII.II'Y OPFICIAI. (Chief Executive Officer or Legally l lesponsible Institulional Oflicial)

I w r l l l y lhal I l ie abcwe IS Irua, corrt.~I. d ~ d c.usl~plele (7 U S C St!~11011 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL NAME 8 TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL (Type or Prrr~l)

0

0

0

0

0

0

0

7 9

1104

208

0

29

' 164

2

DATE SIGNED

'/L *A 3

Page 17: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Ioteraye,icy Hew,! ~u8 i1 rv l NU Thns r e p 1 1s .equlred by law (7 USC 21 43) Failure l o report according l o Ihe rqu la l~ons Call See reverse slde lor

.ddlq~mal Intormltun OIBOWA-AN

resJl an P'I order to ceax a p deslsl and l o be subtecl l o penaltur as PlOvlded lor 111 Secll0n 2150 -c-

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. I FORM APPROVED ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT) I

CASE WESTERN RESERVE UNIVERSITY

10900 EUCLID AVE

I CLEVELAND. OH 44106 I I

3. REPORTING FACILITY (L~s l all locallons where anlmals were housed or used In a ~ l u a l r ewar~h , lesl~ng. lerchlng or exper~me~~la l~o l l , or held lor lhese purposes Altach addlllonal shwls 11 tlecessary )

FACILITY LOCATIONS (Srles)

Case Western Reserve Univesity Cr- . . MetroHealth Medical Center I

2 ) Each prlr~clpat lnvesllgalor has cullsldered allerrml~ves l o pal l~lul procedures

I

3) Th~s I.ILIIIIY IS adlaermy l o the sldllddrds and rcgul.~l~ons under Ihe ALI albd 11 faas required lhal exceploons l o Ihe standards and regulallons be spe~l l led and explained by Ihe p r l n ~ ~ p a l Invesllgalor and dpproved by Ihe I ~ ~ s l ~ l ~ ~ l ~ o t ~ d l A n ~ ~ n d l &re J I I~ Use Cutn~nlllee (IACUC) A sumnlary of all such exceptions Is a l l ached t o thls annual repOrl In a d d ~ l ~ o n lo tdentllylng the IACUC dfrpruved rxceplmns lhls sulnmary includes d b r~e l expld~~dlron ol !he exceplwns. as well us Ihe specles and numbet ol drllmals dtlecled

4 ) The ~ l l t t d181g VelerlltarldII lo1 1111s ~esealch l a ~ l l l l y has dpp#uprlale dulhurlly 10 ellbuie Ihc ~ I O V I S I O I ~ 01 adequale velerlnory care and l o oversee (he adequacy ol olher Jspcclb ol al~ttrul care a ~ l d use

F.

TOTAL NO OF

(~01s. c + D + E)

120

85

698

4 2

502

n

7

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (AMach adrdrlro$,al shcels r l rlccessary or use APHIS FORM 7023-4) '

CEI~TIFICA'I'ION I1Y 1IEADQUAH'rb:S ItESEAHCIi PACII.II'Y OPPICIAI. (Chief Executive Officer or Legally l lcsponsible Inslilutional Official)

I ~ : e r l ~ l y 1tmI lhe above 8s I rw . correcl. JII~ cw~~ple l t . (7 U S.C Sec:llon 2143)

SIGNATURE OF C ATE SIGNED

408

ASSURANCE STATEMENTS

1 I Prolesslo~~ally acceptable standards governing the care. Irealmenl, arid use 01 animals. 111cluding apprormle use of anesthelic, analgesic, and tranquil~ang drugs, prior lo, durlrlg. and lollowlng actual research. teach~ng. lesllng, surgery, or experlntertlatlor!.were lollowed by l h ~ s research tjcil ity.

E Number ol animals upon whlch teaching. enper~menls. research. surgery or lesls were conducled lnvolv~ng accompanying pain or dlslress l o the antmals and lor whrch the use 01 approprlale anesthellc, analgesic. or tranquillring drugs would have adversely alfecled Ihe procedures, results, Or lnlerpretallon of the leachmg, research. exper~ments, surgery, or tests (An explanalion of the procedures producirly patn or distress m these animals and the reasons such drugs were no1 used must be allached lo thds repom

n

0

0

0

0

n

A

Animals Covered By The Anlmal

Welfare Regulal~ons

4. D O ~ S

5 . Cats

6. Guinea Pigs

7 . Hams te rs

8. Rabb~ls

9. Non-human Primales

10. Sheep

I3 Number 01 an~mals bemg bred, cond~l~oned, or held lor use ~n leaching, I e s l ~ , expertments. research, or surgery b u ~ no1 ye1 used IOI such purposes.

3 4

1 .

5 9

0

51

n

3

C Number ol dn~rnals upon which Ieachlng, research. experlmenls, Or

tests were conducted ~nvo lv~ng no paan, distress, or use of paan- relieving drugs.

1 2

5

633

4 2

228

n 3

D upon whlch exper1111enls. leaching, research. surgery, or lesls were conducled ~r~vulvlng accompa~y~ng paan or dlslress l o Ihe Jcl~mills and tor which approprlale aneslhellc, allalgeslc, or Irallquillzing drugs were used

108

8 0

6 5

0

274

n

n

APHIS FORM 7023 (Repla cs V 5 FORM 18 23 (OCT 88). n h l c t ~ IS obsolule )

(AUG 91)

Page 18: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

. Thts reporl IS requ~red by law (7 USC 2143) Failure l o reporl accurdlng ' lhe regulallolls call See reverse s ~ d e lor I t i ler~yr . l~cy htpunl Lull1

resull in an order to cease and d e s ~ s l and l o be subjecl l o penal l~es as f L v~ded lor III Secllon 2150 addll lonal lnlormallon 0180 DOA AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. I FORM APPROVED I ANIMAL AND PLANT HEALTH INSPECTION SERVICE OMB NO 0579.0036 1

I

2. HEADOUARTERC DSCC*""" "-.' -- I wrlh U S 0 4 Include Zil

31-~-0029, CUS~ Id 235 1

I FACILI'IY LOCATIONS (SdesJ

I

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

------------- -- ----------- MIAMI UNIVERSIN

OAST BONHAMHOUSE

OXFORD, OH 450s6 3 REPORTING FACILITY (Llsl all locallons where anlmals were housed or u s ~ d In aclual research, lesr~ng. lt expertmeillallon, or held lor these purposes Atlach add~ttonal

aheels 11 iwcessary )

P e a r s o n H a l l Boyd H a l l

B e n t o n H a l l

5. C a t s

6. Guinea Pigs

Eco logy Resea rch C e n t e r

REPORT OF ANIMALS USED BY OR UNDER CONTROL (

7. H a m s t e r s

A

Anmals Covered By The An~mal

Welfare Reyula l~ons

10. Sheep I

B Number 01 an~rnals bemg bred. cond~t~oned , or held tor use ln leachmy, tesltng expertmerlls, research, or surgery bu l no1 ye1 used lor such purposes

12. O t h e r F a r m Anmals

House M i c e 1 4 1 2

P r a i r i e V o l e s 13 O t h e r Animals

Meadow V o l e s

P i n e V o l e s

1 7 6

-- : Number o l

a r~maI> upon whlch leachln I research. experlmenls. .,r 1eSts were conducled mvolv~ng IIO

paln, dlslress or use of paln- r e l ~ e v ~ n y d ru~ la

--

D Number u l d l~t lnals upon w h ~ h experllnenls. tea~h lng . research. surgery, or lesls were conducled ~ ~ l v o l v l n y accompanying pdln or d~slress l o the alllmdfs and lor whlch approprlat6 aneslhellc, a~lalyeslc, or Iratbqu~l~zmg drugs were 18rort

Number o l an~mals upon whlch teaching. experlmenls. research, surgery or tesls were conducled Involving accornparlymg paln or dlstress l o Ihe animals and lor w h ~ c h Ihe use 01 appropriate aneslhellc, andlgestc, or l ranqul l lz~ng drugs would have adversely affecled Ihe procedures, results, or ~nlerpreta l lon of the leachmg, research. experlmenls, surgery, or lests (An explanatron 01 the procedures producrny pafn or d~slress m these anrmals a n d the reasons such drugs were no1 used must b e attached to lhrs report)

TOTAL NO OF ANIMALS

(CO~S. C + D + E)

2 ) Each p rmc~pa l lnvesllyalor has considered alterl~allves l o palnlul p r a ~.dures

-

-

-

- -

-

-

3) T h ~ s 1a~tl11y IS adhermy l o the sldndards and regulations under the AI I atbd II lads requ~red lha l exceptlons l o the standards and regula l~ons be speul led and e x p l d ~ ~ l e d by the prlnclpal mvesllgator aud approved by Ihe I n s l ~ l u l ~ u ~ ~ d I Arlllnal Care ? I I ~ Use Comm~l lee (IACUC) A surnnlary of a l l s u c h e x c e p t l o n s IS a t t a c h e d t o I h l s annua l r e p o r l III add l l~on l o ~denl l ly lng the IACUC appruved Pxcepllnna, lhls sulrlrnary 111cludes a brlel explmdl lon of Ihe excepllons, as well ds Ihe specles and number o l a n l ~ ~ ~ d l h d l l e ~ l e d

(

- -

- - - - -

4) The ~ l l l e n d ~ t q veterlt!drlala lor It112 resralch Iac~l l IY has ap(mpr la le ablhorlly l o ensure (he provlslon of adequale velerlnary care drld to oversee Ihe adequacy o l olher aspects v l ~IIII~I~I care a d use

CEKTIFICA'I'ION IiY 1lEAI)QUAK'TES RESEAKC11 FACII.II'Y OFFICIAI. (Chief Execut ive Officer or Legally Responsible Insi itutional Oflicial)

I cerl l fy lha l the above. Is trite. c:orrect. dl ld cwnplel r (7 U S C S fx . lm i 2143)

SIGNATURE OF C E O . OR INSTITUTIONAL OFFICIAL NAME 8 TITLE OF C.E.O. OR INSTITUTIONAL OFFICIAL Uype or Prml) DATE SIGNED

-

-

-

-

-

- - - - - -

ASSURANCE STATEMENTS

1) Proless~onally a ~ c e p l a b l e sldndards governlng the cdre, trealmenl. d use o l alrtmdls. ~nc ludmg dpprorldte use o l dnesthet~c. analgesic, and I r a n q u ~ l i r ~ n g drugs prlor lo, d u r ~ n g and lo l l ow~ny actual research, Ieachmg, lesllny, surgery, or experlnleljlallor~ were lollowed by l h ~ s resear~h l d c ~ l ~ l y

(b)(6), (b)(7)(C)

Page 19: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

-1 IS requ~red by law (7 USC 2143) Fa~lure l o reporl according to the regu la l~o~ lb can See reverse slde lor

n order to cease and dews1 and l o be sub1ect l o penal l~es as prov~ded lor III Secllon 2150 addll lonal ~n lo rmd l lon 01 80-DOA.AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE

00 FORM APPROVE NOV - 7 1 ' OM. NO 0.7.-okfi I ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT)

KENT STATE UNIVERSITY

DIVISION OF RESEARCH 8 GRAD. X&lJg- 191 MACC Annex

I KENT. OH 44242 I

3 REPORTING FACILITY (LSI all localions where animals were housed or used In actual research. l e s t ~ r ~ g , leachlny, ", sArtz,o,,,s,,.~..u.., ". ..IC._)C CL..p--- -,dltlonal

sheels 11 tlecessary )

FAClLlrY LOCATIONS (Sdes)

I Cunningham Hall

I

I A 1 B Number o l

Anlmalb Covered By The Anlmal

Wellare Reyula l~ons

animals b a n g bred. cond~ l~oned , or held lor use In Ieachmg, lest1ng. experlmelrls, research. or surgery but no1 ye1 used for such purposes

4 . Dogs I

5. C a t s I

7. H a m s t e r s 1 8. R a b b i t s I 9. Non-human P r t r n a t e s I

I 10. Sheep 1

12. O t h e r Farm An~mals

13. O t h e r An~mals I

I ASSURANCE STATEMENTS

Kent Hall I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Anach .id~drtror~dl SIICPIS 11 I I C L ~ ~ S S ~ W or use APHIS FORM 7023A) '

I 1) Pro less~o~~a l l y acceplable standards governmg the care. Ireatrnenl. and use o l antmals, mcludmg apprormte use o l anesthetic, analgeslc, and tranqulhztng drugs, prlor lo , durlrtg.

and l o l l o w ~ r ~ y actual research, teachmy, lesllng, suryery. or experlrrtenlatlorl were lollowed by l h ~ s research lac l l~ l y

2 ) Each prlr~clpal Invesllyator has considered allerl~allveb l o pa l l~ lu l procedures

F

TOT^^ NO OF A N ~ M A L ~

(cots c + D + E)

3) T h ~ s l i r c ~ l ~ t y IS adherlng l o Ihe slandards and regulir l lor~s under Ihe Acl , and 11 has requ~red thal excepllons t o the standards and regula l~ons be specllled and expla~ned by Ihe prlnclpat rnvrsllyator a r ~ d approved by the tnstrl~rlror~al Anllrtal Care a r ~ d Use Cornrn~ltee (IACUC) A sumn+ary of a l l s u c h excep t ions i s a t t a c h e d t o t h i s annua l r e p o r t In a d d ~ l ~ o n l o lder!tllylrlg the IACUC-ak~proved excepllons. lhls butrlmary ~ncludes a b r ~ e l ex plan all or^ o l the excepllotls, as well as Ihe specles and number o l dn~r r~d ls ir l lecled

E Number o l anlmds upon w h l ~ h leaching experments, research surgery or tests were conducled ~nvo lv~r lg accornpdnylng paln or dlslress l o the an~mals and lor whlch lhe use o l appropriate dneslhel~c. analgeslc, or l ranqu l l~z~ng drugs would have adversely allected the procedures resulls, or tnterprelatlon of the teaching, research. exper~ments, surgery, or tests (An explanairon 01 the procedures producrrlg parn or drstress m these anrrnals a n d the reasons such drugs were not used n w s l be anached l o thrs report)

-

4 ) TIw altt!ndl,lg velerIllarlaII 101 Ihls research taclllly has ilLlOlUpllale authofl ly to ellsu1e Ihe ~~UVISIOII 01 adequirle veterlnary care and l o oversee the adequacy o l other aspccls o l d lwr~a l care afld use.

-

-

- - -

- -

-

-

- -

-

-

CEK'I'IFICA'I'ION 1lY llEAI)QUAUrrICS RESEAKC11 E'ACII.11'Y OFPICIAI. (Chief Executive Officer or Legally Itesponsiblc Institutional Ol'licial)

I c:ertlfy Ihdl llbe above is trlle. 1:orrecI. d11d cottlplele (7 U S C SI?L:~IOO 21 43)

-

-

-

-

-

-

-

-

- -

-

-

- -

c Number 01 al~llrtals upon

leachl"g, resea~ch experiments, Or

tests were conducled lrrvolv~ng rlo paln d~slress or use o l p a w rellevmg drugs -

0 ol dIlllnals w h ~ h exper l l~ le l~ ls. teaching, research surgery or lests were conducled ~nvolv lng accompanymg pdln or d~slress to the a~l lmals and lor which approprlaie aneslhellc allalgeslc, or lrallqulllllng drugs were used

NOT A FOIA DELETION

Page 20: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Thls reporl IS required by IJW (7 USC 2143) Fa~lure l o report accordl t~y to Ihe re(luldt1ol1s can See reverse s ~ d e lor i i ~ ~ ~ ~ ~ g t c t ~ y H t p ~ , l LOIIIIUI NU 01 80-DOA-AN

resull In an order l o cease and deslst and l o be subject to p e ~ ~ a l t ~ e s as prov~ded lor III Secllon 2150 addlllonal lnlormdllon n i+- UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. ~ j - R - o o 3 r I FORM APPROVED ANIMAL AND PLANT HEALTH INSPECTION SERVICE O M 8 NO 0579-0036

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

H~PPLE CANCER RESEARCH CENTER, INC.

4100 S. KElTERlNG BLVD

DAYTON. OH 45439 i ;

I wtth US04

I h

3 REPORTING FACILITY (Llsl el l locaclons where animals were housed or used In aclual research, lestlng, leach~ng, or experlmentatlori, or held lor lhese purposes Al lach addll lonal sheels 11 tlecessary )

F A C l L l N LOCATIONS (Sties)

1 ASSURANCE STATEMENTS

bayttw, t \ ~ ~+<-;r; .39

1) Prolesslonally acceplable standards governmy the care. Ireallnenl, and use of antrnals. ~nc ludmg approrlale use o l aneslhetlc, analgeslc, and I r e n q u ~ l ~ z m g drugs, p r ~ o ~ lo, durmg. and Ioliowlng aclual research, teachlng. Icstlng, surgery, or experlmenlallon were lnllowed by 1h1s resedrch l a c ~ l ~ l y

2) Each pr tnc~pal lnveslogalor has considered allernallves l o pa l l~ lu l procedures

F.

TOTAL NO OF A N ~ M A L ~

( ~ 0 1 s . c + D + E)

REPORT OF ANIMALS USED BY OR

A

An~rnals Covered By The A n ~ m a l

Welfare Regula l~ons

4 . Dogs

5. C a t s

6. Gumea P~gs

7. Hamsters

8. Rabblls

9. Non-human Primates

10. Sheep

., 11. PIQS

12. O t h e r Farm Animals

13. O t h e r Anlmals

b

3) T t ~ s l a ~ ~ l ~ t y IS adt~er lny t o the standdrds and reguldltons u~lder Ihe ALI and 11 hds requtred that exceptlolls l o the standards and regula l~ons be speuhed and explained by Ihe p r l n ~ ~ p e l mvestlgalor and approved by the III~~I~II~IUII~~ AIIIIT~ Care and Use Colnm~t lee (IACUC) A sumnlary o l a l l s u c h e x c e p l l o n s ts a t t a c h e d t o t h l s annua l r e p o r l 111 ~ d d l l , o n l o ~den l l l y lng Ihe IACUC dpproved pxcepllons, 1h1s summary Includes a br le l exp land~on 01 Ihe excepl~ons. as well as the specles a n d number o l d111rna1s al lec led

4) Tlle o l l e r ~ d ~ ~ ~ g velerllldrldII tor tllla resedr~h f d ~ l l l l ~ hdb dl)llruvlldle authofl ly l o ensule Ihc provlsloll o f adequdle velerlndry Ldre d l ld l o oversec the adequaLy o l other JbpeClb o l d ~ w r ~ a l Lare a11d use

UNDER CONTROL OF

B Numbel o l anltnals belng bred. c o n d ~ t ~ o r ~ e d , or held lor use ~n leachmg, lesltolg, experlmetrls, research. or surgery but no1 ye1 used lor such purposes

bd-I A 1 '

NPA Pi'-/d

I

r ' i I '

N/R

I

hr /A

M I A

, ,r '

1 - '

CEKTIFICA'I'ION HY 1IEAI)QUAK'~ES RRSEAHCI1 YACII.Il'Y OFE'ICIAI. (Chief Executive Officer or Legally Responsible Institutional Oflicial)

I certl ly l hd l l l le atxlve is IfllI?, correct. a11d cmnpletr (7 U S C S ~ x : l ~ o n 2143)

SIGNATURE OF C.E.O. OR INSTITUTIONAL OFFICIAL

llecessary or use APHIS FORM 7023.4) '

E. Number o l antmols u w n w h ~ c h teachlng. experlmenls, research, surgery or lesls were conducted lnvolvlng accornpanylng paln or d~slress ro the anrmals and lor whrch Ihe use o l appropr~ale anesthel~c, analgeslc, or lranqulltzlng drugs would have adversely allecled Ihe procedures, results, or lnlerprelatlon of the Ieachmg, research, experlmenls, surgery, or les ls (An explanation of the procedures producrrry parn or drstress ~n these antmals a n d the reasons such drugs were no t used must be attached to thrs report).

RESEARCH F A C l L l N

C Number 01 dl~ lmala upon wh'ch leaching, research. experiments, Or

tests were conducted lnvolvlng IIO

distress, or use o l pain.

rellevlng drugs

(Attach a~ f~dr l rn r~a l sheets 11

D Nulnber allllnals upon w h ~ c h experllnenls. leachmg, research. surgery, or lesls were conducted lr lvolv~ng accompanying p a n or dlstrcss l o Ihe at~lmals and lor which approprlale aneslhellc, allalgeslc, or lrarlqulllztng drugs were used

Page 21: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

See Attached:

Th,s repo,l ,eq, by law ( 7 uSC 2143) Fanlure l o leporl a c c u r d i ~ ~ y l o Ihc fegulJl'oll5 call See reverse slde 101 l " l l e r ~ g ~ l l ~ y R ~ i m l Conlrul NU

addal#onal ~n lo rmd l lun 0180 DOA AN

,esu~l en an o, .I l o cease rlnd dCslSl aud l o be sublecl l o penal l~es as provlded 101 Iu S e ~ l l o l l 2150

Anmals Covered By The Antmal

Wellare Regulalwns

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT O F RESEARCH FACILITY (TYPE OR PRINT)

0 Numbel of anrrnals berng bred. condtl~oned. or held lor use In leaching. lesllng experimen~s. research. or surgery bu l no1 ye1 used lor such purposes

I REGISTRATION NO

31-3-0033 239 I FORM APPROVED OM0 NO 0579 0036

i f h USDA, mclude Zrp

Summa Health System Hosp~tals Akron Clty Hosp~tal Campus Research Adm~n~stratron 5 525 E Market St Akron, OH 44309

TOTAL NO OF ANIMALS

REPORTING FACILITY (LI~I all localhons wlocre antmals were housed 0, used In aclual resudvrh les181ng leachtng or experlmelllatloll. Or held lor lhese purposes Attach addt l~onal

s h e ~ l s t I tteCessJry )

FACILITY LOCATIONS I S ~ l c s l

Dogs 0 I

C a r s 0 I

2 Olhcr Farm A n ~ m a l s 0

0

Mice 0

I

EPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Affach . ~ l ~ ~ l , l r n ~ ~ a l shcels 11 rmcessaw or m e APHIS FORM 701341 '

C Numbel o l Nu,nk, ul ,,,, nJl, upon E. Numbet o l Jnlrr~als upon r h ~ c h leeching.

d l l l r rds u ~ o n whxh exper~~r~enls. exper~menls. research, surgery or tests were wh'ch leachtng. leachtng. research. conducled Irlvolvmg accurnpdnylng p a n or dnslress reseatch. surgery. on lesls were

l o Ihe anamals and lor which Ihe use o l approprlale

exPr 'menls, or conducted ~ ~ ~ v o l w n g aneslhellc. analgestc. or l ranqu~ lmng drugs would lesls were accompartylng pain of h ~ v e adversely a l lec led Ihe procedures, resulls, Or

conducled d~strcss l o lhe JIIII~JIS lnlerprelalton of the leach~ng. research. ~ n v o l v ~ n g no and lor wh,ch app,opr,ale exper~~nenls. surgery, or lesls (An erplanalron 01

paon. dtslress. or aneslhel,c, Iho procedures p r o d u c ~ l y pafn or d d r e s s In these

use o l ~ a ~ n - lra,,qu,l,llng drugs were anmals and Ihe reasons such drugs were no1 used

rehevmg drugs used nws l be attached l o lhrs rep0171

- -

--

-

-

- .-

- - - -

-

-- -

-

-- -- -C

.SSURANCE STATEMENTS

41 11ac .rt~~.and#n~, V C I C ~ ~ ~ W W S I w lluab O~LC~ICII l ~ ~ e l ~ l y has J~I,IU/IIIJI~ .~ulhutnly 10 CII)UIC IIW /OIVYIWOII 01 ~ C Q I I ~ I C . VCICI I I I~ I~ 'age . B ~ N J IU owelsee 11,c ~ , l t ~ , u a v <,I olhe, a ~ p e c l , <#I

.,qlll lad~ c.~.c

Page 22: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

FACILITY SITES .LISTIN0

Lfcensee/Regie t r a n t Namc :

Licensc/Regiat ra t ion Number:

Summa Health System Hospitals Akron City Hospital Campus/Surgical Research Facility

--

31-R-0033

-

Please l i s t below a l l s i t e s t h a t house r e g u l a t e d a n h a l n under t h e above number. BC

su re t o i n c l u d e a l l r e q u e s t e d i n f o r m a t i o n . I f t h e l i n e doe0 n o t a p p l y , please mark it N/h. I f you have more t h a n t h r e e ( 3 ) s F t e o Copy t h i s form a s many t h e 0 an needed before fFllLnq Ln t h e s i t e s .

S i t e No. : 1 Namo/Dcpartmont: Akron C i t y H o s p i t a l Campus/Surgical Research F a c i l i t y

Addreon: 525 E a s t market s t r e e t

Akron, OH 44304

B u i l d i n g : A d m i n i s t r a t i o n B u i l d i n g

c o n t a c t Person: - - - - - - - - --- ----------- -------------- ------------ ------------

S i t e No. : Name/Departrnent :

Addre s 6 :

B u i l d i n g :

Floor/Room:

Contact Pereon:-

North E a s t e r n Ohio U n i v e r s i t i e s C o l l e ~ e o f Medicine

4209 S t a t e Route 44

Rootstown. OH 44272

Department of Comparative Medicine

---------- ----------- ------------ ------- - - - - - - - - - - - - -

S i t e No.: Name/Departrnent:

Address:

B u i l d i n g :

FLoor/Roorn:

Contact P o r o o n : P h o n e No. :

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 23: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

T I r e . ! requlred by law (7 USC 2143) Failure l o report according lo the rrgulallollr can See reverse slde lor

resu.1 In a wder to cease d ud deslsl and to be subjecl to penalties as prov~ded lor 111 Secllon 2150 addllronal lnlormdl~on 01 80 DOA-AN -- UNITED STdTES DEPARTMEKT OF AGRICULTURE 1 REGlSTRATlON NO.

ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED I OM8 NO 0579.0036 I

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT) SURGICAL RESEARCHIDEVELOPMENT

4545 CREEK ROAD ~ o \ i \ 6 2QQQ I 1 CINCINNATI. OH 45242

1 3 REPORTING FACILITY (List all locat~ons where anrmals were housed or used In aclual research. lest~ng, teaching, or exper$meulatron, or held lor these

1 1 FACILITY LOCATIONS ISlles)

1 See attached

I (Aflach d~lrcl~lmrral shoets 11 rlccessary or use APHIS FORM 70234) ' HEPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FAClLlT

--

Number ol alulndls upon w111ch experlaroenls, leachmg, research. surgery. or lesls were conducted t~~vulvlng acrompanylng paln or dlst lC6~ l o Itre anlmdls and lor whlch approprmte anesthellc, a~~a lges~c , or Iral~qulllzlng drugs were used

A

Animals Covered By The Anrmal

Wellare Reyulat~ons

N ~ I ol anlrndls dpu81 w h ~ h leachrng. experlmenls, research, surgery or tests were conducted ~nvo lv~ng accompdnytng p d n or dlslress to Ihe anlrnals a r~d lor which Ihe use ot approprlale aneslhelc, andlgeslc, or lranqulllzlng drugs would have adversely allecled the procedures results, or lnlerprelalron ot the leachlng, research. experlments, surgery, or tests (An explanalron 01 the procedures productng parn or drstress m these antrnals and the reasons such drugs were no1 used nrust be anached l o thts repod)

F.

TOTAL NO OF ANIMALS

(CO~S. C + D + E)

B Number ot an~mals berng bred. cond~t~oned, or held lor use ~n leachtng. lesllng. exper~rnenls. research. or surgery bul not yet used lor such purposes

C Number ot du~rr~als upon whlch teaching. research. experlrnents, or tests were conducted ~nvo lv~ng no pan. dlslress, or use 01 paw, relrevlng drugs

I I I I I

ASSURANCE STATEMENTS

1 I Proless~or~ally acceptable slandards governing the care. Ireatrnent, and use o l antrnals. tncludmg approrlale use o l aneslhetrc, analgesic, and Iranqu~l lz~ng drugs, prior lo, during. and tollowlr~y aclual research, teachmg. Iesllng. surgery, or experlnrentallon were lnllowed by lhla rebedrch l a c ~ l ~ t y

10 Sheep

1 1 P~as

12 Olher Farm Ammals

Goats

21 Each p r l r ~ ~ ~ p a l lnvesllgalor has consrdered allernallves l o pal l~lul procedures

1325

174

3 , Thrs IdcrI~ty IS adttertny l o the sldndards and reguldllo~ls under the Act, and It tlas requ~red that exceptions to the slarldards and regulallons be specrlred dnd ewplerrted by the prmclpal tnveslrgalor a r~d approved by Ihe I n s l ~ l ~ ~ l l u ~ ~ d l Arltrnal Care and Use Co~nlnlltee (IACUC) A sumnlary of al l such ercept tons I s a t tached l o thls annual r epo r l III addrllon to rderttltylng Ihe IACUC dpproved r x c e p l ~ o ~ ~ s . t h ~ r surrlrnary ~ncludes d Lmel expldnalron of Ihe exceplrons. as well ds Itre specles and numbel o l y r l ~ r ~ d l s allected

4 , Ttte dl let~dlng velerrnilrliln lor I h ~ s reseilrch laclllty has ilppropfwte Julhorlly l o ensure the provlsro~~ of ildequale veterlnilry care .md l o oversee the adequacy ol other aspocls o l d~wrtal care aild use.

CEKTIFICA'I'ION H Y 11EAI)QUAWES HESEAKC11 PACII.II'Y OFPICIAI. (Chief Executive Officer or Legally ILesponsible Inslitutional Official)

I c:erllty that the above 1s trtrr?. i:orrt?cl, i l l ~ d Cwtbplete (7 U S C Sra:tro~~ 2143)

DATE SIGNED

Page 24: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Site: 1 Ethicon Endo-Surgery, Inc. ---------- --------- Status: Active 4545 Creek Road ---- ------- --- -----------

Cincinnati, OH 45242 -- ---------------- County: Hamilton

Site: 2 Snowhill Farm Status: Active 305 1 Snowhill Road

W. Harrison, IN 47060 County: Dearborn

---------- -------- : ------- -------- -----------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 25: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Thls report IS requlred by law (7 USC 2143) Falure l o reporl accordtng l o !he regulallons can resull In an order l o cease and destsl and l o be subject t o penalties as provlded lor III Sectloll 2150

See reverse s ~ d e lor a d d ~ t ~ o n a l ~n lo rmd l lon

I 3 REPORTING FACILITY (List all locallons where animals were housed or used In actual resrd~ch, lesllrlg, leachtng, or experlmelltalloll, or held lor lhese purposes Attach a d d ~ t t o l ~ a l

sheels 11 ~ i k ~ e s s a r y ) I

UNITED STATES DEPARTMENT OF AGRICULTURE , ANIMAL AND PLANT HEALTH INSPECTION SERVICE L . - - - - L - a

I

Shriners Hospital for ~ h i l d r e n ~ & P 2 fi : AN^ 3229 Burnet Ave Y

Cincinnati, OH 45229-3095 I .,. .,,. ,. .

I I FAClLlPl LOCATIONS (Sfles)

I 1 REGISTPnTION NO.

h I FORM APPROVED

L OMB NO 0579-0036

1 6 '

2. HEADQUART£ 'h USDA.

O f l ' u d ~ ~ c c D

SHRINERS HOSPITAL FOR CHILDREN _ _ _ _ . _ _ - 3229 BURNET AVENUE

CINCINNATI, OH 45229

Research Support Division I sth Floor, 3229 Burnet Avenue I

Anlmals Covered By The An~mal

Wellare Regulattons

anlmals being bred. corrd~l~oned, or held tor use In leach~ng, tesllng. experlrnellts, research, or surgery but no l yet used lor such purposes

4. Dogs

10. Sheep I

12. Other F a r m An~mals

13. Other Animals

> Number o l D Nulntrer ul aIlllnals upon E Number o l anlrnals upon w h ~ h leaching. experiments, research, surgery or tests were

F d111111dls upon w h ~ h experl l~~errls. which leaching, tearh~ng, research. c o n d u ~ l e d ~nvolv lng accompdnylng paw or d~s l ress research. surgery, or tesls were

l o the animals and lor whlch Ihe use o l approprlale TOTAL experlmenks Or conducled ~ n v o l v ~ n g aneslhellc, andlgeslc, or lrarlqulllzlng drugs would OF A ~ l ~ A ~ s tests were acrompanylng pdm or have adversely allecled the procedures, resulls, or conducled d~slress l o lhe a ~ ~ l r n d l s lnlerprelallon 01 Ihe leach~ng research, lnvolv~ng 110 and WhlCh approprlale

exper~ments, the procedures surgery, p r o d u c w or tesls p a n (An or drslress explanation in these 01 ( ~ 0 1 s c +

pdln dtstress or aneslhetlc allalgeslc, or 0 + E) use 01 pain drugs were

anmal r a n d the reasons such drugs were not used

rellevlng drugs used nrust be attached to this reporl)

I ASSURANCE STATEMEWS

1) Proless~onally acceplable standards governlng the cdre. Ireallnenl. dnd use o l anlmals, ~ncludlng dppror lde use o l aneslhel~c, analgesic, and t ranqul l~z lng drugs, prlor lo, d u r l r ~ g and l o l l o w ~ r ~ g actual resedrch, teachmg, lestlng. suryery, or erperlrrbentallorl were lollowed by lhls resedr~h l a ~ l l ~ l y

2) Each p r l r c ~ p a l lnvesllgalor has ~ o n s ~ d e r e d a l le r~~a l l ves l o pall l lul procedures

3) Thls IJLIIIIY IS adleerlng l o Ihe standards and r e g ~ ~ l a l l o ~ t s under Ihe ALI. and 11 ttds requ~red lha l excepttons l o the standards and regulations be spec~hed and explained by Ihe prlnc pal lnvesllgalor aud approved by the IIISIIIIIIIOII~I Antmal Care a ~ ~ d Use Comrn~l lee (IACUC) A summary o f a l l such excep t ions 1s a t t a c h e d t o this annua l repor l . In add~t lon l o ~ d e n t l l y l r ~ g !he IACUC approved ~ x r e p l l n n s , thls sul r l l rwy Includes d brlel expldlldllon 01 lhe excepllons, as well ds Itbe species and number of anmd ls dtlecled

4) The a l l e r d ~ t t g velurlliarlatl lor Ihts research lacll l ly has dpl"Up~lJle aulhorlly l o erlsure Ihe p r u v l s l ~ ) ~ ~ o l adequale velerlnary care and l o oversee the adequacy o l olher aspucls 01 a z w ~ a l care a t ~ d use

CEKI'IFICA'I'ION BY 1IEAI)QUAH'l'ES RESEAHCII FACII.II'Y OFE'ICIAI. (Chief Executive Officer or Legally Itesponsiblc Inslilulional Oflicial)

l)

APHIS F C ~ R ~ X 7b23 .<, . , ,. ,,- ; ( >,<I.! Y. . : - > ( ht,, ~ t h I, ,, ,,h:>,,;, 1, . , (LtJ'.? 5 1 I

DATE SIGNED

9 / 2 0 / 0 0

Page 26: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor
Page 27: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

1":s reporl I, requ~red by law (7 USC 2143) Fa~lure l o reporl according l o Ihe regulallo~rs can See reverse s ~ d e lor I~ t le rdym~cy Rcpurt Cu~alrul Nu

result ~n an order to cease and deslst and l o be sublecl l o penall~es as p rov~ded lor 111 Secllon 2150. addltlonal ~nlormot lun 01 80-DOA-AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED

3 1-R-0043 OMB NO 0579.0036

ANNUAL REPORT OF RESEP~RCH F A C I L I ~ ' (TYPE OR PRINT) ..&,

r* '

L

2. HEADOUARTERS RESEARCH FACILITY /Name and A d d r e c c rc r-~.o-lowd with USDA. rnclude t i

31-R-0043, Cust Id 2 4 0

------------------ - - - - - - - -- ----------- ---------- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ----- --------

r n r n m ~ e H e a l t h Educa t ion Bui ld ing

I I FACILITY LOCATIONS (Sdes)

Heal th Educat ion/Block H e a l t h Sc ience B u i l d i n g I

3) T t m taclllly IS adhermy l o the slandards arid regu la t lo~~s under the Acl, and I t hds requlred that exceptions l o the slaudards and regulallons be specllled and explained by the pr~nclpal mvesllgalor and approved by the I n s l ~ l u t l u ~ ~ a l An~mal Care and Use Commlllee (IACUCI A summary o f a l l s u c h e x c e p l i o n s i s a t t a c h e d t o l h i s a n n u a l r e p o r t In addlt lon l o ~ d e i t l ~ l y ~ n g the IACUC.appruved rxcepleons. thla sulrbnaary includes a brlel explanallon 01 the except~ons, as well as the specles and number 01 an~r r~a ls allecled

REPORT OF ANIMALS USED BY OR

A

An~rnals Covered By The An~mal

Welfare Regulal~ons

4. D O ~ S

5. Cats

6. Gumea P~gs

7. Hamslers

8. R a b b ~ t s

9. Non-human P r ~ r n a t e s

10. Sheep

. 1 1 . P~as

12. O l h e r Farm An~rnals

13. O t h e r Animals

ASSURANCE STATEMENTS

4 ) Tlw JII~:II~III~ ve1er111drla11 lor Ihla resad~ch tdclllly has apptoprldle du lhor~ ly l o ensure the p r o v l s ~ o ~ ~ o l adequdle velerlndry care and l o oversee Ihe adequacy o l other Jspeclb o l anltrlal care atad use

I I Prolesslonally acceplable slandards governing h e care. I real~nenl . and use 01 animals. ~ncludlng approrlale use 01 aneslhellc, analges~c, and l ranqu~hzlng drugs, proor lo, dur~rbg. and lo l l ow~ng aclual research, leaching, lestlng, surgery, or exper~rr~ental~on were lollowed by lhls research Iac~l t ty .

2) Each prlnclpal ltlvesllgalur has considered allernatwes l o pamlul procedures

UNDER CONTROL OF

B Number 01 an~mals bemg bred. c o n d ~ l ~ o r ~ e d , or held lor use bn leachlng, leslnbg, exper~menls. research, or surgery bu l 1101 yet used lor such purposes

0

0

0

0

0

0

0

fl

0

0

CERI'IFICA'I'ION H Y 1IEAI)QUAH'l'ES RESEAHCII FACII.II'Y OFFICIAI. (Chief Executive Officer or Legally Ilesponsible Institutional Official)

I (arloly thal Itbe above IS l r w lo r rc .~ I and complel r (7 U S C Src IIOII 2143)

RESEARCH FACILITY

C Number 01 JIIII~IJ~~ upon which leact'lr'g, research, exPerlmenls, Or

lesls were conducted ~ n v o l v ~ n g no p a n , d~slress, or use 01 p~lll. rellevlrlg drugs

0

0

0

20

3

0

0

0

C)

0

SIGN

L P r l

~ A U G [ { I i

F.

TOT^^ NO OF A N I ~ A L s

( ~ 0 1 s . c + D + E)

8

3

0

69

5

2

0

3 7

0

0

1AHach a t i ~ d ~ t r n r ~ a l sheets 11

0. Nulnber al,llnala upon w111ch experllrlenls. leaching, reseerLh. surgery, or lesls were conducled ~nvolvtng accompanylny paln or distress l o I~IC anlrnals and lor which approprlale aneslhellc, allalgeslc, or Irallquillzing drugs were used

8

3

0

4 9

2

2

0

3 7

0

0

DATE SIGNED

necessary or use APHIS FORM 7023A) '

E. Number o l anlrnals upon whlch leaching. expertmenls, research, surgery or les ls were conducled mvolvlng accornpanymg paln or dlslress l o the an~mals and lor whlch the use 01 appropflate aneslhellc, analgesic, or lranqull lzlng drugs would have adversely allecled the procedures, results, or mlerprelatlon o l l he leachlng, research. exper~ments, surgery, or lesls (An e x p l a n a f m 01 the procedures producrny pain or drstress m these an~mals a n d the reasons such drugs were not used nws t be attached to this report).

0

0

0

0

0

0

0

0

0

0

(b)(6), (b)(7)(C)

Page 28: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Thls reporl 1s required by law (7 USC 2143) Fa~lure lo reporl according l o lhe regufallolls Call See reverse s ~ d e lor IIII~~IJCJUI~LY HI put1 L ~ t i l r o i NU

resull 11, an order to cease and destsl and l o be subject l o pe~q l t l es as provlded lor III Secllon 2150 add~ l lona l ~n lo rma l lon 01 80-DOA AN

UNITED STATES DEPARTME 1 REGISTRATION NO ANIMAL AND PLANT HEALTH I FORM APPROVED

3/- A?- 004'7 OMB NO 0579.0036

* " E A D O ~ ~ ~ ~ - - ----'--- -.-" '- '.a^-- --.A ""A,̂ "' ,n,,,r,ara,j USDk mclude zrp (

(TYPE OR PRINT) '*..

OHIO WESLEYAN UNIVERSITY

61 S SANDUSKY STREET

DELAWARE. OH 43015

3. REPORTING FAClLllY (Llsl all locat~ons where animals were housed or used ~ n ~ ~ t u a l research, testtng, teach~ng, or experunenlallon. or nelo lur lvtase lJullJv.r.. -IIYlh add~t lonal sheels 11 tlecessary )

. 1 1 i

FACILITY LOCATIONS (Sites)

I

I

I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FAClLlPl 1AItach a d ~ d r l ~ n r ~ a l sheets 11 ,lecessarv or use APHIS FORM 7023AJ ' 1

ASSURANCE STATEMENTS

I ) P ro less~o~~a l l y a ~ ~ e p l a b l e standa~ds governlng Ihe care. trealmenl. and use o l an~rr~als, tncludmg approrlale use ot aneslhetlc, analges~c, and tranqulllzlng drugs, p r ~ o r to, dur l r~g. and lollowlng aclual resedrch, leachlng lesllng, surgery. or erperlrrlentatlorl were lollowed by lhls research Iac~ l l l y

A

Arllmdls Covered By The Anttnal

Wellare Regulal~ons

4 Dogs

5 C a t s

6 Gu~nea P~gs

7 Hamsters

8 R a b b ~ t s

9 Non-human P r m a t e s

10 Sheep

11 PIQS

12 O t h e r F a r m A n ~ m a l s

13 O t h e r An~mals

b

2) Each prlrlclpal Illvesllgalor has collsldered aller~ballves l o pall l lul procedures

/

3) This l d ~ l l l l y 1s ddhertny l o Ihe s l d l l d ~ r d ~ and reguidl~o~bs under the Act a:bd 11 has required lha l excepllorls l o Ihe standards and regulallons be specllted and expla l l~ed by the prlnc pal lnverl lyalor aud approved by Ihe I n s l ~ l ~ ~ l ~ o r ~ a l Anlmal Care and Use Commlllee (IACUCI A summary o l a l l s u c h e x c e p t i o n s IS a t t a c h e d t o this a n n u a l r e p o r l In a d d ~ l ~ o n l o ~dernl~lylr lg Ihe IACUC dl~proved Pxcepllons, lhls sulrlmary ~ncludes a b r ~ e l exp la~~d l lon 01 the except~ons. as well as the specles and number of JIIIIIIJIL aflecled

B Number o l animals bemg bred. cond~t~oned or held lor use ~n ledchmg tesllng expenmenls. research or surgery but not ye1 used lor such purposes

4) Tlw dl lerbd~tq velerllwrIdIt lor ttlls resedrch lacll l ly has dppruplldle dulhorl ly l o enbulP the prov1~1011 01 adequate velerlllary Ldre and l o oversee the adequacy o l otlier dspwla 01

DATE SIGNED

9- l g - 0 0

F.

TOTAL O~ A N l ~ A ~ s

( ~ 0 1 ~ c + D + E)

C Number 01 dn~lnals upon which leachlnq, resedrch. experiments Or

tests were conducled ~ l ~ v o l v ~ n g no paln d~slress, or use o f pain-

r e l ~ e v ~ n g drugs

0 Nulnber dl,llndIs upon w h l ~ h experl~nenls. leachlng research. surgery or lests were conducled lrlvolvlng accornpanylng p a n or d~slress l o Ihe atbmals and lor which Jpproprlale anesltlellc, allalgeslc, or trallqull121ng drugs were llsed

E Number 01 an~rrlals upon w h ~ h leach~ng. experiments. research surgery or tests were c o n d u ~ l e d l l lvo lv~ng accompdnymg patn or dlslress to Ihe dnlmals and lor w h ~ h Ihe use o l approprlale dneslhellc, andlgeslc, or lranqull lr lng drugs would have adverbely a l l r c led the procedures, resulls, or mterprelallon 01 the leachmg, research. exper~menls, surgery, or tests (An explanalron of the procedures producrr~g paln or drstress m these anrmals a n d the reasons such drugs were not used nlusl b e anached to thrs report)

Page 29: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Th~s report IS requ~red by law (7 USC 2143) Fadure l o report according to the regulatlotls call result In an order l o cease and des~st and l o be sublecl to penalt~es as provlded lor III Secllon 2150

See reverse slde lot addttlonal lnlormilt lon

-- , , I rnclurfe ZIP ----- --------------- ------- - - - -----

ANNUAL REPORT OF RESEARCH F A C I L I ~ T 2 7 2000 ----- - - - - - - - --------------

w HIRAM COLLEGE --- - - - - - - - - - - --- ----

(TYPE OR PRINT)

I 1 , l l l - " *

I HINSDALE HALL

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

'- ' -.. __. . I P.O. BOX 1838

1 REGISTRATION NO. I 31- K- 00C3 OM0 NO 0579 0036

2 HEADOUARTERS RESEARCH F A C l L l N (Name a n d Address as rearslercd wrth US04

- . " . . , HIRAM. OH 44234

3. REPORTING FACILITY (Llst all local~ons where an~mals were housed or used In aclual research, lestmg, teachl~~,. -. -. sheets 11 necessary )

I I FACILITY LOCATIONS IS~les)

I

REPORT OF ANIMALS USED BY OR UNDER CONTROL C

A

An~mals Covered By The An~mal

Wellare Regulal~ons

4. Dogs

B Number 01 antmals bemg bred. candilioned, or held for use ~n leachmg, leslmg. experlments. research. or surgery bul not yet used lor such purposes

0

7. H a m s t e r s

I

0

10. Sheep 0

12. O t h e r F a r m An~mals

I

0

13. O t h e r An~mals

ESEARCH FACILITY (AHach dd~drtmr~dl stieels 11 recessdrv or use APHIS FORM 70234) '

0

2 ) Each p r l r ~ c ~ p a l mvesllgator has cons~dered a l le r l~a t~ves to patnlul procedures

-

- -

-

-

-

-

- -

-

-

1

ASSURANCE STATEMENTS

3) T h ~ s I a ~ l l ~ l y IS adherlrlg l o the sldndards and regulal~ons under the ALI and 11 tbas required Ihal excepllons t o Ihe standards and regulations be s p e u l ~ e d and explained by the pr lnupal mvestlgalor and approved by the I n s l l l ~ ~ l l o ~ ~ a l AnllrlJl Care drld Use Cutnmlllee (IACUC) A sumnlary 01 a l l s u c h eXCeptlOnS I s a t t a c h e d to t h l s annua l r e p o r t In addlluon t o ~den t~ ly~rbg the IACUC approved rxcepllnlrs thts summary mcludes d brlel explallallon of Ihe excepttons, as well .IS the specles and number o l an11n~1s a l l e ~ l e d

F.

T ~ ~ A L OF

(cots c + D + E)

. Number of arllmals upon which leachlng research. experiments, Or

tests were conducted ~ n v o l v ~ n g 110 p a n d~stress, or use o l pal11 rehevlng drugs

T C

-

- -

- -

-

-

-

- - -

- - -

4) The allerbdlllg ~~I~IIIIJII~II lor ttils rehedr~h f a c ~ l ~ t y has i lppropt~ale aulhurlly to ensure Ihc provlslon o l adequate veterinary care dnd 10 oversee the adequacy o l olher ~ s p c c ~ s o l atwnal care atbd use

I ) Proless~or~ally acceptable standards governtng the care. treallnelll, and use o l arrimals, l l ~ c l u d ~ n g ilpprortate use o l aneslhelic. analgesic, and t ranqu~l lzmg drugs, proor to, durmg. and l o l l o w ~ r ~ y actual research, leaching, lesllng, surgery, or expcrtnlenlatlorl were lollowed by l h ~ s research laclhty

Nulnber allllnJls upon w h ~ h e x p e r ~ ~ r ~ e f ~ l s . teachmg. resear'h. surgery or tests were conducted tnvotvmg accompauylng paln or dlstress to lhe antmals and lor which approprlale anesthellc, allalgeslc, or trarlqulllzlng drugs were lrspd

E Number o l anlrrtals upon w h ~ h leachmg experlments research surgery or tests were conducled ~nvolv lng accompanying paln or dlstress t o Ihe ~ n ~ m a l s dnd lor whlch the use o l approprlale dnestheltc analgesic, or tranqulllzlng drugs would have adversely atlected the procedures, results, or lnterpretatlon of the teachmg, research. expertlnents, surgery, or tests (An explanatron of the procedures producrriy pain or distress m these anrrnals a n d the reasons such drugs were no1 used n w s l b e attached to thts report)

CEHTIFICA'I'ION I i Y 1IEAI)QUAKTES RESEAHCII FACI1.Il'Y OFFICIAI,

DATE SIGNED

A P I ~ I S FORM 7023 d ~ i " I r 1 l h r 1 , \ ijr, 1 1 1 j

l f 4 u s 9 1 )

(b)(6), (b)(7)c

Page 30: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

T l c i , tr~pcnl is rrcllr~rrd idw 1; IJSC 21431 F ~ I I I J ~ ~ ! 16 1epor1 J(.I.UIUIIIIJ 1 0 I ~ c I U ~ ] ~ J I ~ I ~ ~ ~ ! I S id11

rc5ull f r l art order lo CC~IL. altd dez~sl a l d la be iublccl lo petnallles JS pou ldrd lor 11) Srcllo#b 2150

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO II ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED .

2 1 -17 _ L", OM6 NO 0579.003& y 1 1 \ - -- I I 2, HEADOUAR---- -"c* DPU FACll IN /Name and Address. as reyrstefed wdh.GDA

- - - - . - --.

KAUKE HALL Room 42 (primate colony room)

.- ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT)

w

Animals Covered By The Anlmal

Wellare Regulalions

"lc'ude Zrp

COLLEGE OF WOOSTER, THE 931 COLLEGE STREET WOOSTER, OH 44691

animals being bred. condilloned, or held lor use In leaching, lesling. experimenls. research. or surgery bul no1 ye1 used lor such purposes.

3 REPORTING FACILITY (List all l a a l ~ o n s where an~mals were housed or used In actual rerearrh, leslllbg, leacnlng. or rrpr~wn.omr.-.. -. - - 2h addlllonal sheels 11 ~~ecessary) Psychology Department

FACILITY LOCATIONS ISrtesJ

13. O the r Animals

4. Dogs

5. C a t s

6. Guinea Pigs

7. Hams te rs

8. Rabbi ts

9. Non-human P r ~ m a t e s

10. Sheep

11. Pias

12. Othe r Farm Animals

C Number 01 alilmals upon whlch leachmg. research. experimenls. or ~ e s & were conducled mvolv~ng no pam, dislress, or use 01 paln- relieving drugs.

0

0. Number u l at~rrnals upon whrch experitl~enls. leaching, research, surgery, or lesls were conducled ~nvulvrng accompanying paln or dislress l o the animals and lor whlch approprialc aneslhelic, aualyesic, or tranquilizing drugs were used

L Number ol anlrnals upon which leaching. experiments. research, surgery or tests were conducled involving accompanying pain or distress l o Ihe an~mals and lor which the use 01 appropriale aneslhellc, analgesic, or lranquillzing drugs would have adversely affected !he procedures, resulls, or inlerprelatton o l Ihe leaching, research. experimenls, surgery, or tests. (An explanation 01 the procedures 6 o d u c r r 1 ~ pain or distress i n these animals and the reasons such druos were not used " n~us t be attached to thfs report).

KAUKE HALL Room 29 (experimental t e s t i n g REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach adrditro~~al sheets r l rlecessary or use APHIS FORM 7023A) '

A 10. Number 01

I

ASSURANCE STATEMENTS

I ) Pruless~or~ally acceptable standards governing the care. Ireilllnenl, and use ot anllnals. ~nclud~ng approriale use 01 anesthetic, analgesic, and lranqu~l i rmg drugs, prior to, during. and lollowlng actual research, leachiny, lesling, suryery, or experlnlenlalion were lollowed by Ihls research lacllily.

2) Each pr l rc~pa l mvesligalur has considered allernalrves l o p a l ~ ~ l u l procedures

TOTAL NO. OF ANIMALS

3) Th~s lacr l~ly 1s adherlny l o Ihe slmdards and reyulalluns under the Acl. amd 11 has requlred that excepllons l o the slar~dards and regulal~ons be specllled and explained by the p r ~ n ~ ~ p a l ~nvestryalor and approved by the 1nr1111r11ur1~I Anlliial Care and Use Cutnmlllee (IACUCI A sumnlary 01 al l such ercep l ions IS a t tached t o l h l s annual report In addtllon l o ldenlrly~ng Ihe IACUC approved exLepllOnS. Ihls rulnmary lncludes a b r ~ e l explanallon o l Ihe exceplluns. as well as Ihe specler and number o l ar11111dla allected

4) The allrnd~log velerlnarlall lor Ihlr research taollly has ap lnUp~~ale ~u lhu r l l y l o ensure Iho pruv1Sio11 u l adequate velerillary care and l o oversee Ihe adequacy u l olher aspects ul alwnal care a r~d use.

CEHTIFICA'I'ION HY 1IEAI)QUAKTES RESEAHCll PACII.II'Y OPPICIAI. (Chief Executive Officer or Legally I<esponsible Institutional Official)

I c:erllly thal the atxrve is true, c:orrc:cl. a r~d COIII~I~I~ (7 U S C Sts:~r~r i 2143)

S I DATE SIGNED

I 1 ' 1 I APHIS FORM 7023 (Rep la~es VS FORM 18-23 (OCT 88). w h ~ c h IS obsolete )

( A U G 91)

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UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. - ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED . 31-R-54 OMB NO 0579.0036

ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT) COLLEGE OF WOOSTER, THE 931 COLLEGE STREET

WOOSTER, OH 44691 I

1 3. REPORTING FACILIW (~1st a11 locatlorn where an~mals were housed or used In actual research, testlng. teacnmg, or .xrsl... =...,.,.., -. . sheets 11 ~lecessary.) BIOLOGY D E P A R q E N T - - - I

FACILITY LOCATIONS ISrterl

MATEER HALL, Room 203

CEHTIFICA'I'ION H Y 1IEAI)QUAK'I'b:S RESEAKC11 E'ACI1,II'Y OFFICIAI. (Chief Executive Officer or Legally Itesponsible Institutional Ol'licial)

I certlly lhol Ihe a h v e is true. correct. altd complete (7 U S.C Sectmr~ 2143)

DATE SIGNED

F.

TOTAL NO, OF

(cols. c + D + E)

1

I I , P H I S FORM 7023 ( R r p l d ~ e s VS FORM 18-23 (DCT 88). * r h ~ c t ~ IS ohsolate )

(AUG 9 1 )

I) Proless~or,ally acceptable standards governing the care. treatment, and use o l animals, including approriale use ot anesthetic. analgesic, and tranqullizing drugs. prior lo, during, and loltowiny acluat research, teaching. testing, surgery, or exper~n~enlation were lollowed by lhls research locility.

2) Each prfnc~pal invest~yator has consldered allernalives l o pailllul procedures.

3) Th~s faclllty is adhering to the standards and reg~~la lwns under the Act. and i t has requ~red that exceptions to the slafbdards and regulattons be specilied and explained by the prtnc~pal tnvesllgalor and approved by the l n s l ~ t ~ ~ t i u ~ d Anmal Care and Use Cu~nrnlttee (IACUC) A sumnlary ol al l such except ions is a t tached l o th is annual report . In add~l lon l o ~denl i ty ir~g the IACUC.approved exceplinnr. thls sumnary includes a briel explanallon o l the excepl~ons. as well as the speclesand number o l an~l l ld ls ollected

4) The atlrfdla,g veterlnarlall lor lhls fesedrch f a c ~ l ~ t y has i lppoprlole iluthorlty l o ensure thc provlslon ol adequate veter~nory care and l o oversee the adequacy ol other aspccls o l a~tirrml care a11d use

(Anach a~tiditiorial sheets if

D, ol irllllnals upon which experi~r~enls. Ieachmg. research. surgery. or lesls were conducled involving accompanying pain or distress lo the allimals and ,or which appropriale

allalgesic, or Irar,quilizing drugs were used.

1 -

RESEARCH FACILITY

C Number o l animals upon which leaching. research. experiments. Or

tests were conducted involving no paln, distress, or use o l pala- relieving drugs.

REPORT OF ANIMALS USED BY OR

A

Animals Covered By The Animal

Wellare Regulalions

4. Dogs

5. C a t s

6. Guinea Pigs

7. H a m s t e r s

8. Rabb i t s

9. Non-human Primates

10. Sheep

11. Pias

12. O t h e r Farm Animals

13. O t h e r Animals

ASSURANCE STATEMENTS

necessary or use APHIS FORM 7023A) '

E Number o l an~mals u p n which teaching. experiments. research, surgery or tests were conducted involving accompanying pain or dislress l o the an~mals and tor which the use of appropriate aneslhellc. analgesic. or tranquilizing drugs would have adversely attecled the procedures, resulls, or

. interpretation of Ihe teaching, research. experiments. surgery. or lests. f h explanation d the procedures producing pain or distress in these animals and the reasons such drugs were not used nwst be attached to this report).

UNDER CONTROL OF

B. Number of animals being bred. condilioned. or held lor use in teaching. testing, experimenls. research. M surgery bul not ye1 used tor such purposes.

Page 32: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

Thls r e ~ o r l IS requ~red by law ( 7 USC 2143) Fa~lure l o reporl accordmy l o the rrgulallons can See reverse s ~ d e lor l n l c r ~ g e ~ l ~ y Htpor l Curilrul N u '

resull In dn order l o cease and destst and l o be sublecl to pellallles as provrded lor 111 Secllon 2150 addr l~onal ln lorrnal~on 01 80 DOA AN

WRIGHT STATE UNlVERSlN

LABORATORY ANIMAL RESOURCES

106 OELMAN HALL

UNITED STATES DEPARTMENT OF AGRICULTURE ANIM~. AND PLANT HEALTH INSPECTION SERVICE

I DAYTON. OH 45435 3. REPORTING FACILITY (L~s t all localions where an1rnal5 were housed or used In aclual research, lestlrtg. I~~CIIIII~. or experrrnelltatlon, or held lor lhese purposes Al lach a d d ~ l ~ o n a l

sheets 11 ~ ~ r ~ e s s a r y ) 1

1 REGISTRATION NO. I FORM APPROVED 31R-055 OMB NO 0579 0036

2 HF,&OOUART~~ O C C . - A - - ~ ---" --' I h U S 0 4

rncrude

1 I FACILITY LOCATIONS (Siles)

See Attachment I

REPORT OF ANIMALS USED BY OR UNDER CONTROL C

A

Anlmdls Covered By The Anlmdl

Wellare Regulat~ons

6. Gu~nea Pigs

B Number of an~mals bemg bred cond~lloned, or held lor use ~n teachlng, testlog experlrnenls. research or surgery but no1 yet used lor such purposes

0

7. H a m s t e r s

I

0

9. Non-human P r t m a t e s

10. Sheep

11. PIQS

Lesser Shrews I 0

I

0

0

0

12. O t h e r F a r m An~mals

I ASSURANCE STATEMENTS

0

I

RESEARCH FACILITY /Attach a ~ l r d ~ l r o r ~ a l s l~oels 11 rlecussarv or rtse APHIS FORM 70234) '

C Number o l a~r l l r~a ls upon whlch leachlng, research. erperlmenls. or lest5 were conducted ~nvolvrng no paln, d~stress, or use 01 paon- re l iev~ng drugs

TOTAL NO OF ANIMALS

(CO~S. C + D + E)

D Nulnber d,lllndls w h ~ c h experltr6errts teachlng, research surgery or lesls were conducted IIIVU~VII,~

accornpanylng pdln or dlslress l o Ihe an~mals and for whlct, approprlale aneslhellc allalgeslc or lrallqulllzlng drugs were used

I 1) Prolesslorlally acceptable slandards governmy the care. Ireatrnenl. d ~ ~ d use 01 anlrnals, lncludrng approrrale use 01 dnesthetrc, analgeslc, and l ranqu~ l rz~ny drugs, prlor l o durlrtg.

and lollowlrly actual research, leach~ny. teslwg. suryery, or experlmentatron were lol lowed by lh l r resear~h lac~lr ty

E Number o l anlmals upon whlch teachrng. experiments research, surgery or tests were cor~ducled ~ ~ l v o l v l n g accompdnyrrlg paln or d~stress to the an~mals and lor whlch Ihe use o l appropriate dneslhet~c analgeslc or t ranqwl lnng drugs would have adversely allecled the procedures, results, or Inlerprelallon of the teachrng, research. experunents, surgery or tests (An explanatron of the procedures producrny parn or drstress i n these anrrndls and the reasons such drugs were not used must be attached l o thrs report)

2) Each prtnclpal lnvestlgator has ~ o n s ~ d e r e d allerrtal~ves l o pamlul procedures

3) Th~s l d ~ t l l l y IS adherlng l o the standards and regula11o11s under the ALI. altd I t has requ~red lha l excepllons l o the slandards and regulallons be specllred dnd explarned by Ihe prmc rpal rnvesllgator and dpproved by the Ins l l l u t~or~a I A n m d Care a r ~ d Use Cornmlllee (IACUC) A sumntary 01 a l l s u c h exceptions 8s a t t a c h e d t o l h l s annua l r e p o r t In addll$on l o l d e n l ~ t y ~ n g Ihe IACUC approved Pxcepllnns. lhls suwnary l~bcludes d brief expldrwlror~ of Ihe exceptlolls as well ds the speclea and numbel 01 dnllnals d l e c t e d

4) Tlw JIISI,~II@Y velerrr~arld!a lor Ihlh (esedrch IJLIIIIY has app top t~a le aulhor~ly to ensure the p r u v ~ s l o ~ l 01 ddequale velerlrlary care and l o oversee the adequacy o l olher aspects ot dnlmal cilre alld use

CEI~I'IFICA'I'ION f3Y 1IEAI)QUAH'~tCS RKSEAHCII FACII.II'Y OFE'ICIAI. (Chief Executive Ofticer or Legally Ilesponsible Insiilutional Oflicial)

I cerlrly lha l Ihe nbuve IS Irlle, c o r r l r l . a r ~ d ~1mple t t ' (7 U S C SI:~ IIOII 2143)

SIG DATE SIGNED

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FACILITY SITES LISTING .

License/Registration Number: -R - 0 5 5

Please list below a l l s i t e s t h a t house regula ted animals under t h e above number. Be s u r e t o include a l l requested information. I f the l i n e does not apply, p lease mark it N/A. I f you have more than t h r e e (3 ) sites copy t h i s form a s many times a s needed before fillina i n t h e s i tes . .

S i t e NO. : 1 Name/Department: ~ a b o ~ ~ + ~ ~ ~ qnim;r 1 R ~ ~ ~ , ~ ~ - na17+- * - ns

Affairs Facility Adckess: 41 no hi ,-a s ~ ~ ~ ~ + -

Dayton, OH 45428

Building: Veterans Administration Hospital

Floor/Room: Building # 315 - Research Services

Dayton, OH 45435

Fawcett Hall

Floor/Room: 514A & 514B Fawcett Hall

S i t e

Dayton, OH 45435

Contact Person: --------- --- -------- -------- ------ - - - - - - -- - - - - - - ---- ----- -------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

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FACILITY SITES LISTING .

Licensee/Registrant Name: Wright State Universi tv

License/Registration Number: 3 1 -R- 0 5 5

Please list below all sites that house regulated animals under the above number. Be sure to include all requested information. If the line does not apply, please mark it N/A. If you have more than three (3) sites copy this form as many times as needed before fillinu in the sites..

------ ----------

Site NO.: 6 Name/Depeent: Laboratory Animal Resources - Health Sciences Facility

Address: 053 Health Sciences

Dayton, OH 4 5 4 3 5

Building: Biological Sciences/Health Sciences

Site No. : Name/Department: ,

Address:

Building:

Contact Person: Phone No. :

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 35: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

UNlTLlO STATE8 DEPARTMENT OP AORtCULTURC ANIMAL AND PLANT HEALTH IHSPLCTION 8 lRV lCE

ANNUAL REPORT OF AESEARCH FACILITY (TYPE OR PRINT)

CLEVELAND STATE UNIVERSITY

RESEARCH & ECONOMIC DEVELOPMNT

TOTAL NO OF ANlMALr

4 . Doys

5. Cals

13. Q u m o a P I Q S

7 h a r n s l o r s

8 R a b b ~ l s

Q N o n - l u n a r P r ~ r n a l o s

10 Shoop

11 Plus

12 Ol lw F a r m Arwna19

SlO DATE SiONEO

0

Page 36: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Thls reporl ts lequlred by law (7 USC 2143) Fa~lure l o r e p r t according lo Ihe rr!plallolls call r2sult In an order 10 cease and des~sl and l o be sublecl l o penalttes as provlded lor 111 Sectton 2150

See reverse slde lor hllerdger&cy Raporl Conlrul No

add~l~onal ~ r ~ l o r m d h n . OI8O-DOA.AN

-dI UNITED STATES DEPARTMENT OF AGRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

-:' NOV 1 5 2000

I REGISTRATION NO. I FORM APPROVED

31-R-0059 OM6 NO 0579.003

2. HEADOUARTERS RESEARCH FACILITY (Name and Address. as regrstered wrlh Us04 rnclude ZIP Code) " -

- . - ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT) Milacron, Inc. 3000 Disney St reet Cincinnat i , Ohio 45209 Status: Act ive

-

Milacron, Incorporated, Cimcool Laboratory

3. REPORTING FACILITY ( L w all local~ons where antmats werehoused or used In arlual research. lesllng, leachmg, u b mer~lat~on. or held lor lhese pu rpose Allach add#tlonal sheets 11 necessary)

FACILITY LOCATIONS ISrlesJ --

3000 Disney Street, Cincinnat i , OH 45209 I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach a~ l i d tmr~a l sheets r l necessary or ure APHIS FORM 70234) '

7. Hamsters I I I I

A

Animals Covered By The Anmal

Wellare Regulalions

5. Cats

6. Guinea P~gs

8. Rabbits

9. N o n - h u m a n P r ~ m a t e s

B. Number 01 animals being bred. conditioned, or held lor use In leaching, lesling. experiments. research, or surgery but no1 yet used lor such purposes.

10

11. Pias

12. Other Farm Animals

ASSURANCE STATEMENTS

1 ) Proless~onally acceplable slandards governing Ihe a r e . Ireatmenl, end use 01 animals, i l lclud~ng opproriale use 01 aneslhelic, analgesic. and Iranquilizmg drugs, prior 10. durlllg. and lollowiny actual research. leaching, lesling, surgery, or erper~menlalion were lnllowed by l h ~ r research lacilily.

C Number 01 animals upon which leaching- research. exPerimenls. Or

tests were conducled i n v o l v ~ n ~ no paan, dislress. or use 01 pain- relieving drugs.

228

I .-

13. Olher An~mals

2) Each p~ l r~c lpa l Invesllgalor has c~nsldered allernal~ves l o pamlul procedures

-

I

3) nus ldcblity $s adhermg lu the standards and reguldllons under \he Acl. and I has requwed that excepllons l o the slanddrds and regulallons be specllled dnd explained by the prtnr,~paI tnvestlgalor and approved by Ihe I n s l ~ l ~ ~ l r u r ~ a t Anunat Care and Use Co~nmlllee ilACUC1 A summary 01 al l such except ions is a t l ached l o l h i s annual repofi. I,, jddltlon l o ldenl~lylng the IACUC approved PXCepllollS, lhls sulrlmary Includes a brlel explan~llOn ot the excepttons. as well as Ihe speaes and number 01 an1111~ls al lwled

0, Nulnber al,llnals upon whlch erperi~r~enls. leaching, research. surgery, or tests were conducted ~nvuk ing accompanying pain or dislress to Ihe animals and lor which aneslhelic, allalgesic. or

drups were used.

129

4) Tt,e ~ l l r n d l l l g veterwlarwl lor I h ~ s resedrch l a ~ ~ l ~ t y has dppoprIale d~ lhur l ly l o ensure the prov~s~ol l ol adequdle velerltwy Lare and l o oversee Ihe adequaLy UI other aspects dlwnal care aud use

CEKTIFICA'I'ION RY IIEADQUAHTKS RESEAKCII I"ACII.11'Y OTPICIAI, I (Chief Executive Officer or Legally Itesponsible Institutional Official)

I r r r l l l y lhdl I l ~ e above Is InlP..l orrerl dlld r tmple l r (7 U S C Set Itnu 2143)

SI I DATE SIGNED

E. Number o l anlnwls upon which leaching. exper~ments, research, surgery or tests were conducted involv~ng accompanying pain or distress l o Ihe animals and lor which he use of appropriale aneslhellc, analgesic. or lranquilizing drugs would have adversely allecled Ihe procedures, resulls. or inlwprelalion of the leaching, research, experimenls, surgery. or lesls. (An explanation d the procedures producing pain or distress i n these animals and fhe reasons such drugs were not used must be attached l o this report).

- 0-

F.

TOTAL NO, OF

(cols. c +

D + E)

357

Page 37: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

T h ~ s reporl IS requlred by law (7 USC 2143) Fa~lure to reporl accord~ny l o the regulallo~ls call resull In an order l o cease and deslsl and to be subject t o penallles as p rov~ded lor 111 Sectlon 2150

See reverse s ~ d e lor I~~ lu rdyu~ ,cy Htpor l Lu~a l iu l fdu

addll lonal l n l o r m ~ l ~ o n 0180 DOA.AN - .

I

- FACILITY LOCATIONS (Srles)

Doug1 ass Research Fac i 1 i t y

UNITED STATES DEPARTMENT OF AGRICULTURE 1. REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE

FORM APPROVED

2. HEADOL' - - . . . - . . . . . .

' -ed wrlh US04

ANNUAL REPORT OF RESEARCH FACILITY I

(TYPE OR PRINT) ST. VINCENT MERCY MEDICAL CENTER

2213 CHERRY STREET

I TOLEDO, OH 43608

oct 1 1 99 ?O /ars 3 REPORT IN^ FACILITY (LISI all locat:ons where admals were housed or used In aclual resadrrh, lesllny, leaching, or experwnelllatloll, or held lor lhese purposes Attach d d d l t ~ o r ~ a l

shrels 11 Ilecessdry )

4. Dogs

REPORT OF ANIMALS USED BY OR UNDER CONTROL C

5. C a t s

A

Awmals Covered By The A t~ lmd l

Wellare Reyula l~ons

9. Non-human P r ~ r n a l e s

lo. Shee

B Numbel o l animals bemg bred. cond~t~oned , or held lor use ~n ledch~ny, lesllng. exper~ments. research. or suryery but no1 yet used lor such purposes

12. O t h e r Farm An~mals

I ASSURANCE STATEMENTS P

11 Prolasslor~ally acceptable standards governing the care. Irealrnerll. and use o l anlrnals. Including apprormte use o l aneslhellc, analges~c, and l r a n q u ~ l ~ z ~ n g drugs, praor lo, dur~r tg, and lollowlrlg actual research, teachmg, leslmg, suryery, or exper~n~enta l~on were lollowed by lhla research l a c ~ l ~ t y .

ESEARCH FACILITY (Aliach dl/rdrtrnrlaf slm?ts r l r lecessav or use APHIS FORM 702.3.4) '

2) Each pr l r~clpal Invesllyalor has cons~dered aller~baltves l o pal111ul procedures

3) Th~s I d c ~ l ~ l y IS adtnerlny t o Ihe slallddrds a l ld reguldltons under Ihe Acl, and 11 has requlred that excepltons l o the standards and regula l~ons be spectlled and explained by !he pr~nc:~paI tnvesltyator and approved by the Ins l r t~ r l~or~a l Anl l r~al Care aud Use Cutnmlllee (IACUC) A summary 01 a l l s u c h e x c e p t i o n s i s a t t a c h e d to t h i s annua l reporl. In a d d ~ t ~ o n l o bdenl~fy~rtg the IACUC-al~proved exceptmns, t h ~ s sulurnary includes a brlel e x p l a n d ~ o n 01 Ihe exceptions. as well as the specles and number 01 anmdls j l l ec led

F.

T O T ~ L NO OF A N ~ M A L ~

( ~ 0 1 ~ . c + D + E)

; Number o l a n ~ n ~ a l s upon which leachl"y, research. exPerlrnents, Or

tests were conducted mvolv~ny no patn, d~slress, or use 01 paan- rellevlny drugs

4 ) Tlw d l l e ~ t d ~ t t y v e l e r l n ~ r l d t ~ lor Ihlb resedrch t a ~ l l l l y has SppIUprldle duthurlly l o ensure Ihc provlsloll o l ddequale velerlnary care and l o oversee the adequacy o l olher a s p c c l ~ o l ~ I ~ I ~ J I care o t ~ d use

CEHTIFICA'I'ION HY IlEAI)QUAH'rI*:S RESEAHClf FACII.II'Y OFFICIAI. (Chief Execulivc Officer or Legally Ilesponsible Inslilutional Oflicial)

~ t t

D Nulnber al,lrndls upon whlch experllrienls. teaching, research, .. suryery, or lests were cunducled ~nvolvtng accompany~ng p a n or dislress l o the an~mdls and lor which appropriate aneslhellc, allalgeslc, or lral,quillzlng drugs were used

DATE SIGN D p

E. Number o l an~rnals upon whlch leach~ng. exper~menls, research, surgery or tesls were couducled mvolvmg accornpanytng p a n or dlslress l o the an~mals and lor whlctl Ihe use o l approprlaie aneslhellc, analgesic, or lranqull lzing drugs would hove adversely allected the procedures, results, or lnterpretallon of the teachmg, research. exper~rnents, surgery, or tests (An explanatron of the procedures p roducr r~y parn or drstress ~n these anmats a n d the reasons such drugs were not used nwsf be attached to thrs report).

Page 38: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Th~s reporl IS requ~red by law (7 USC 2143) Fallure l o reporl accurdllly to Itre regulatlolrs can resull In an order l o cease and des~s l and l o be sublecl l o pelralt~es as provlded lor III Sectlon 2150

See reverse s ~ d e lor addl l~onal lnlormatlon

Y

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. ANIMAL AND PLANT HEALTH INSPECTION SERVICE I FORM APPROVED

OMB NO 0579 0036 I ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT)

31-R-0063, Cust Id 246 rnclurle L p Co

TAL

13951 TERRACE ROAD

EAST CLEVELAND, OH 441 12

I ) 3 REPORTING FACILITY (LA! all locallons where anlmals were housed or used In actual research, testorbg, leachmy, or experlmelutdt~or~, or held tor these purposes Altach add~ltorral I sheels 11 lbecessary ) I

FACILITY LOCATIONS (Stles)

21 Each p r l rupa l lrrvesllyalor has considered alterrmllves l o pat t~ lu l procedures

-- -

REPORT OF ANIMALS USED BY OR

A

Animals Covered By The An~mal

Wellare Regulal~ons

4. Dogs

5. C a t s

6. Gu~nea P~gs

7. H a m s t e r s

8. R a b b ~ t s

9. Non-human P r m a t e s

10. Sheep

, 11. Plus

12. O l h e r F a r m An~mals

13. Olher Animals

ASSURANCE STATEMENTS

3) Thts taclllty IS adhermy t o the slal lddrds a w l reg11ldllo81s under Ihe ALI. albd 11 has requ~red Ihal excepllons t o the s t a ~ ~ d a r d s and regulallons be spe~ l t led and expldlned by the prlnupal lnvesllgalor a r ~ d approved by the I n s t ~ t ~ ~ t l o ~ b a l Arlllrlal Care and Use Colnlnlllee (IACUCI A sumnlary of a l l s u c h exceptions I s a l t a c h e d to l h l s annua l r e p o r t III addlllon l o ~ d e r l l ~ l y ~ r ~ g Ihe IACUC a l~p fuved excepllons Ihls su~rlmdry includes a bnet explanal~on o l Ihe exLeptlorrs as well as the specles and numbel o l ~IIIIII~II a l t e ~ t e d

4) Tlw d l l o r d l ~ ~ g velcrttldrldrl lor Ihts resedlch taol l ly has dpptoprldle dulhorl ly to ellsure Ihc pruvlslolr 01 i ldequale velerlrrary care and to oversee the adequacy u l olher aspecls o l d8,lrrlJI care and use

1) Pro less~o~~a l l y acceptable srandards governing the care. Ireallnerbt, and use 01 anlmals. ~ncludmg approrlale use o l anesthetic, analgeslc, and l r a n q u ~ l ~ m ~ g drugs, proor lo, durrr~g. and lollowlny aclual research, teachlng, lesllng, surgery, or expersrrberltallorb were lollowed by lhls research l a c ~ l ~ t ~

UNDER CONTROL OF

0 Number 01 animals bemg bred, corbd~t~orred, or held tor use ~n leachmg, lesllng, experlmenls. research, or surgery b u ~ not yet used lor such purposes

1

I

CEKI'IFICA'I'ION IiY 1IEAI)QUAK'I'ES KICSEAKCII I2ACII.II'Y OFFICIAI. (Chief Executive Officer or Legally Ilesponsible InstiLutional Oflicial)

t w r l ~ f y lhal the dbove 1s Irate. wr r thc l , a d complete (7 U S C S~:(:IIIBII 2143)

SI DATE SIGNED

F.

TOTAL NO OF A N ~ M ~ L ~

( ~ 0 1 ~ . c + D + E)

9- I

I

RESEARCH FAClLlrY

C Number of a t ~ ~ m a l s upon which leaching, research. exPerlments, Or

lests were conducted ~rrvolv~ng IIO

paln, dlslress, or use 01 palll. rehev~ng drugs

1

t

(Atlach a t l~d r t ro~~a l streets 11

Number ol allllnalb upon whlch experllrtenls. teaching, research. surgery, or lesls were conducled ~ n v o l v ~ n g accompanymy paan or distress l o lhe an~mals and lor which approprlale

allalgeslc, or tranqulllzlng drugs were used

I

I

t$

rrecossary or use APHIS FORM 70234) '

E. Number o l ammills upon whlch leaching, experiments, research, surgery or tests were conducled ~nvolv lng accompanying pain or dlslress l o Ihe arrlmals and lor whlch Ihe use 01 approproate anestheltc, analgesic, or tranqulllzlng drugs would have adversely aflecled the procedures, results, or lnlerprelallon 01 the teachmg, research. exper~rnents, surgery, or tests (An explanalron 01 the procedures ~ r o d u c w patn or dlsfress m these antmals a n d the reasons such drugs were no! used n ~ u s t b e attached l o thrs report)

I w

Page 39: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

ANNUAL REPORT OF RESEARCH FACILITY (TYPE O R PRINT)

This epvrl is eqbtrea 3y 3w 1' ibC - 4 2 1 -Jllure r e w r l ~ ~ c o r o l n g 10 ?e d q u oi l5 ~ 0 1 1 > r e reverse L l i l r 31 C ~ t r i , - r r 1 .

resull ~n a n order l o Cease and deslsl and l o be 5ubleCl l o penallles as provtdea lob 1 8 Srcllon 2150 adall lonal l n l o r m ~ l l o n d 180 SOA A N

YOUNGSTOWN STATE UNIVERSITY

ONE UNIVERSIlY PLAZA

YOUNGSTOWN, OH 44555

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

- 4 20W

I - 3. REPORTING FACILIlY (LEI a11 locaf~ons where an~rnals were housed or used In ac tud research, lesllrlg. leach, ..,. -. -. .-. ...--- ,-.,----. -3d1110nal

sher ls 11 necessary

1 REGISTRATION NO. I FORM APPROVED

31-R-0066 OM6 NO 05790036

2 HEADQUARTERS RESEARCH FACILITY (Name a n d Address as reorstered wrih tnciude L o Cod

Ward -her Science Hall

CEl~1'IF1CA'I'ION HY 1IEAI)QUA.liTb~S ltI<SEAUC1I FAC11.1l'Y OFFICIAI. (Chief Executive Officer or Legally I{csponsible Institutional Of'licial)

1) Pruless~ot~al ly acceplable slatldards governmy Ihe care, Irealtne,bl. and use o l a.>6lrlals. ~ t t c lud~ng dpprorlale use o l aneslhel~c. analgeslc, and l ranqu l l~ l tng drugs. prlor lo , dur l r~g. and lollowlrby aclual research, leach~ng. losllng, suryrry, or experllrlerllJllorl wer lnllowed by lhls research f a ~ l l l l y

2 ) Each p r11~1pa1 InveSIIyaIor has collS8aered allerrmlwes 10 palnlul procedures

31 Thlr l a c ~ l ~ l y IS adher~ng l o the slandatds JMI regulal~oo~s under the Acl. and 11 ha.. rerlu~red Ihs l exceptlolls l o the s lar~dards and regulal~ons be specllled and explaloled by Ihe pr~nt:lpaI tnvestlgalor a l ~ d approved by Ihe I~V,III,~IOU~,~I Anrlrlal Care m d Use C o ~ w r ~ ~ l c e e (IACUC) A summary o l a l l s u c h excep t ions is a t t a c h e d t o l h ~ s annual r e p o d . In addtlton l o ldenl#lytrlg the IACUC-approved excepltnm, lhos auorbrnary tncludes a :nlet explillldllon 01 Ihe excepllolls, as well as Ihe species aod number o l an1111a1a Jllecled

4 ) The allrrld$nlg veterwaru&# lor 11115 research lacltlly has appopv~d le aulhorlly l o ellsure the provlsloll u l Jdequale velerllldry care d l d l o oversee !he adequacy (11 olher aspcclr of ~ l ~ m n r l l c u r attd use

rlecessaff or irse APHIS FORM 70234) '

E Number o l a n l m ~ l s u w n w h ~ h leaching, experlrnenls. research, surgery or les ls were conducled ~nvolv lng accompanying paon or dlslress l o Ihe anlrnals and lor whlch lhe use 01 approprmle anesthellc. analgeslc, or lral lqull lzlng drugs would have adversely a l lec led the procedures, resulls, or lnterprelallon of the leaching, research. expermenls, surgery. or les ls (An expianatron 01 the Drocedures P r o d u C w PJrn o r distress m these anrmels a n d the reasons such drugs were not used must be anached lo thrs repod).

REPORT OF ANIMALS USED BY OR

A

Animals Covered By The An~rnal

Weifare Regulsl~ons

4. Dogs

5. Cars

6. Gumea P~gs

7. Hamslers

8. Rabb~ls

9. Non-human P r l r n a l e s

10. Sheep

11 . P ~ a s

12. O t h e r F a r m A n ~ m a l s

13. O l h e r An~mals

ASSURANCE STATEMENTS

DATE SIGNED

10/17/00

S

F.

TOTAL NO OF ANIMALS

(cOls. c +

o + E)

UNDER CONTROL OF

B Number o l anma ls bemg bred. condllloned, or held lor use ~n leachmg. lesll l lg. experlrnenls. research. or surgery but not ye! used lor such purposes.

RESEARCH FACILITY

C Number of ~ w r t a l s upon whlCh leachtn(l.

research. experlrnenls. or [errs were conducted ~ l ~ v o l v ~ n g no paan, dtslress, 0, use o l p a w rellevmg drugs

NO COVERED

AP;IIS FORM 7 0 2 3 I - , ; :; .OCi 38, ~ n ~ r i i 1s onbJ~:it: 1 , AUC; 91 1

l ~ n a c l ~ dclrdrtrnrlai sheets 11

D, Nu,r,ber ol a,,,lnals upon wt.~.h experllllenls. left, hlng, research, su-cjery, or tesls were co.ducled ~ ~ l v o l v ~ n g ac~ornpanytng paln or di..lress l o Ihe arl~rnals

lor wh,ch Jpprop a,,,!slhellc. al,algeslc, or Ir,,,,qulllrlng drugs were us,.d

S F i x m

-

Page 40: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I 3 REPORTING FACILITY (LISI all locallons where animals were housed or used ~n actual resedrrh, lesrlrlg. leachtng, or e x p e r ~ m e r ~ t a l ~ o r ~ , or held lor these purposes Al ldch add~ l lo r~a l

sheels 11 llecessary I

FACILITY LOCATIONS (S~les)

1

See reverse slde lor I I I I L~~CJFI IL~ HL~UI I UIIIIIIII NU Thlz regor1 15 requared by law (7 USC 21431 Fallwe l o reporl accordlr>y l o lhe reg~llal lol ls Call

add~l lonal lnlormdllon 0180-DOA AN resL'll I an order to cease and deslsl and l o be subjecl 10 penalt~es as provlded lor 111 Secllorl 2150

See attached

-- 'JN, ED STATES DEPARTMENT OF AGRICULT

A N I ~ A L AND PLANT H U L T H INSPECTION S&& 1 1 2000 - .

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

I A

An~mals Covered By The An~mal

Wellare Reyuiatlons

1 REGISTRATION NO. FORM APPROVED O M 6 NO 0579-0036

- 2 HEADOUA USD4

n c e p

CUYAHOGA COMMUNITY COLLEGE

11000 PLEASANT VALLEY ROAD

PARMA, OH 441 30

B Number of anmals bemg bred, cond~ l~oned , or held lor use In leach~ng, lesllng, experlments. research. or surgery bu l no1 ye1 used lor such purposes

4. Dogs

5. C a t s

6. Gu~nea P~gs

7. H a m s t e r s

8. R a b b i t s

9. Non-human P r ~ m a t e s

10. Sheep

11 PIQS

12. O t h e r F a r m Animals

13. O t h e r An~mals

Gerbils

ASSURANCE STATEMENTS

I I REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach acl rdr l~o~~al slwefs 11 rlecessary or use APHIS FORM 7023A)

'

1) Proless~onally acceptable s la~rdards governlng Ihe care. I real rnml. and use o l an~mals. ~ n c l u d ~ n g dpprormte use 01 aneslhellc, analgeslc, and I r a n q u ~ l ~ z ~ n g drugs, prlor lo, durrng. and lo l low~ng aclual research, leaching, teslmg, surgery, or e x p c r ~ n ~ e n l a l ~ o n were lollowed by lhls resedrct~ lacrllly

2) Each pr~rbc~pal lnvesllyalor has cons~dered a l le r r~a l~ves l o p a ~ ~ ~ l u l procedures

F.

T O ~ A L OF A ~ l ~ ~ ~ s

( ~ 0 1 ~ . c + D + E)

3) TINS Idc~lr ty IS adlberlng t o the standards and regulal~outs under the Act. and II has reclu~red thal except~ons l o the slarldards and regulations be s p e c ~ l ~ e d dnd explained by the prrnc~pal ~nvestlgalor and approved by Ihe l r ~ s l ~ l ~ ~ l ~ o r ~ a l Anllnal Care and Use Cotnmttlee (IACUC) A summary of a l l s u c h e x c e p t i o n s is a t t a c h e d to t h i s a n n u a l r e p o r t In addlllon l o ~denl t lymg Ihe IACUC-approved nxcepllnns, thla bumrrmry 111cIudt.s a brlel explanallon 01 lhe exceplrons, as well as Ihe Species and numbel 01 dr11111dls sflecled

E. Number o l an~rnals upon whlch leachlng. expertmenls, research. surgery or tests were conducled lnvolvtng accompanylrlg paln or d~slress to lhe antmals and lor whlch the use of spproprrale aneslhellc, analgeslc, or lranqulllzlng drugs would have adversely af fected Ihe procedures, resulls, or Interpretallon ot the leachmg, research. experiments, surgery, or les ls (An explanation of the procedures ~ r o d u c l w pain or drsffess m these animals a n d the reasons such drugs were not used must be attached to thrs report).

C Number 01 dnllnalb upon which leaching, research. exPerl'nenls, Or

lest5 were conducted ~nvolv lng IIO

paln, dlslress, or use o l pain-

rellevlng drugs

4) Tlte ~ l l t : ! d t ~ q VelerllIJrldII 101 Ihrs research t a ~ l l l t y has dppIup1IJle dulhorlly to erlsule Ihe provlslolr o l ddequsle velerllldry care drld l o oversee ltre adequacy o l olher aspects o l a t> t t rd care a81d use

- -

-

- -

-

-

-

-

-

- -

D Nulrlbar al,llnals w111ch exper~n~enls. leachlng. research. surgery, or lesls were conducled lrlvulvlng accompanying paln or d~slress l o Ihe anrrnals and lor which appropriale aneslhellc, al,algeslc, or Iranqulllrlng drugs were used -

-

-

-

-

-

- -

I J A P H I S F 9 R W 7023 -,, , , ,. 4.- r ,.4lV4, : r , ,'; ,: 1(.1 8 h 1 ,,,I, t , I:, , > ~ I V , I , , I ~ . ,

\ A d G Y l l

-

&

CE:IiI'IFICA'I'ION BY IIEA1)QUAICTk:S RESEAHCI1 FACII.11'Y OFFICIAI. (Chief Executive Officer or Legally Ihsponsiblc lnstiluiional Oflicial)

I l .erl l fy lhdl llae ah lve I S lrlle, c.orrt?LI. dl ld ~.o l l lp le le (7 U S C S':I.IIOII 2143)

SIGNAT

I I

DATE SIGNED

''/''u

Page 41: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

31 -R-0067 Site: 001 Status: Active

Veterinary Technology Dept A-Building, A-145 & A-233C 11000 Pleasant Valley Road Parma, OH 441 30-51 99 County: Cuyahoga

------------ ------------ ----- -------- ------------ (b)(6), (b)(7)(C)

Page 42: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

T h ~ s report IS requ~red by law (7 USC 21 43) Fa~lure to report accordmg to the regulatlons can Set reverse s ~ d e for result ~n an order to cease and des~st and to be subject lo penalties as prov~ded lor ln Sectlon 2150 addlt l~nal lntormat l~n

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO.

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

2. HEADQUARTERS RESEARCH FACILITY (Name and Address, as registered wlth USDA include Zip Code)

NAMSA, Inc. 2261 Tracy Road Northwood, OH 43619

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

I

3 REPORTING FACILITY ( L I s ~ all locations where antmals were housed or used In actual research, testmg. teachlng, or exper~mentatlon, or held tor these purposes. Attach add~t~onal sheets if necessary.)

FACILITY LOCATIONS (Sites)

REPORT OF ANIMALS USED sYC

A.

Animals Covered

By The Anlma Welfare Regulatbons

l UNDER CONTROL

6.Nurnber of animals bang

bred. cond~t~oned. Or held for use In teachmg, testlng, experlments. research, or surgery but not yet used for such purpo5es

: RESEARCH FACILITY (Attach additional sheets 41 ns

C. Number of anlmals upon

whlch teachlng. research. expenments, or tests were conducted mvolv~ng n o pain, dtstress. 01 use of paln- rellevlng drugs

D. Number of antmais upon wh~ch expertments. teachlng, research. surgery, or tests were conducted onvolvlng accompanylng p a r or dhstress to the anmals

and for whlch appropriate

anesthetic, analgesic, or rranqullmng drugs were used

--

essary or use APHIS FORM 7023A)

E. Number of antmals upon whlch teachlng experlments, research, surgery, or tests were conducted lnvolvlng accompanylng p a n or dlstress I 3 lee ati.nais and for whhcP, the use 0: apprilpnkte anesthetlc, analges~c, or tranquilmng drugs would have adversely affected the procedures. results, or ~nterpretation of the teachmg, research. experlments, surgery, or tests e n explanallon of the procedures producmg p a n or dtstress m those anmals and the reasons such drugs were nor used musr be arrached lo rhrs reporr)

TOTAL NO

OF ANIMALS

---

4. ~ o g s

6. Guinea Pigs

7. Hamsters

8. Rabbits

9. Non-human Primates

10. Sheep

1 1 ., Pigs

12. Other Farm Animals

I I I I I

ASSURANCE STATEMENTS

1) Professionallyacceptable standards governmg the care, treatment, and use of antmals mcludmg approprtate use of anesthetic, analgesic. and tranqu~llz~ng drugs, prvor to, durtng and following actual research. teachlng, testlng, surgery. or experlmentatlon were followed by this research fac~lity

I I I I 15 0

517

0

109

0

0

2

r)

13 Other Animals

2) Each prlnclpal investigator has consbdered alternatives to pamful procedures

3) Thls lacllcty IS adher~ng to the standards and regulatlons under the Act and It has required that exceptlons to the standards and regulatlons be speclfled and explatned by the prlnclpal lnvestbgator and approved by the lnst~tut~onal Anlmal Care and Use Cornmottee (IACUC) A surnmaryof al l such exceptlons 1s attached l o th is annual report I n addmon to ~dentlfymg the IACUC-approved exceptlons, this summary lncludes a brlef explanat~on of the except~ons, as well as the specces and number of anlmals affected

121

0

4) The attending veterinarianfor thls research facllity has appropriate authorny to ensure the provision of adequate vetennary care and to oversee the adequacy of other aspects ol animal care and use.

I CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL I

0

0

(Chief Executive Officer or Legally Responsible Institutional Official) I certify that the above is true, correct, and complete (7 U.S.C. Section 2143).

121

0

S

0 0

nnr)

DATE SIGNED

11-30-00

Page 43: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I rnclude 7 - -- '-'

C, : r LJ?i 31-R-0072, C U S ~ id 526

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

ALLERGY LABORATORIES OF OHIO, INC I

See reverse slde tor reporl 1s reqtrlred by law ( 7 USC 2143) Failure 1, report accord~r~y l o I l le regulallolls call '1 tn an order l o cease and des~s l and to be sub, :cl l o penall~es as prov~ded lor 111 S~CIIO~ 2150 add111011dl lr l formallon 01 80 DOA-AN

I 623 E. ELEVENTH A V E N U E I

- UNITED STATES DEPARTMENT 'OF AGRICULTURE

ANIMAL AND PLANT HEALTH I 65PECTION SERVICE

I COLUMBUS, OH 4321 1

3. REPORTING F A C I L I N (Llsl all locations where anlmals were housed or used In actual research, tesll shsels 11 IleLessary)

I REGISTRATION NO. I FORM APPROVED O M 0 NO 0579-0036

2. HEADQUARTERS RESEARCH FACILITY (Name a n d Address, as reyrstered wrlh US04

ttach a d d ~ l ~ o r ~ a l I 1 1

FACILITY LOCATIONS (Srtes)

I

REPORT OF ANIMALS USED BY OR UNDER CONTROL 0 --

A / B Number o l

Anrmals Covered By The Antmal

Wellare Regulations

anrmals belng bred, ~ o i ~ d ~ t ~ o n e d , or held lor use In leachlng, les1111g. experlmeilts. research. or surgery bu l no1 yet used lor such purposes

4. Dogs

5. C a t s

6. Guma P~gs 20 7. H a m s t e r s

8. R a b b ~ t s

9. Non-human P r ~ m a t e s

10. Sheep

. 11 Plus

12. O t h e r F a r m An~mals

I IESEARCH FACILITY (AHach a~lrdrlror~al sheets 11 rlecessdry or use APHIS FORM 702341

'

: Number o l a t ~ ~ ~ r ~ a l s upon wh~ch leachlng, resedr~h, experltnenls, or tests were conducled ~rrvulv~rtg 180 paln, dlslress, or use 01 ~ ~ I I I -

rehevmg drugs

D Number u l atwnalb upon w h ~ h experllllenls, leach~ng, research, surgery, or lests were conducted lnvolvlng accompanylng pam or d~slress l o the a ~ ~ l m i l l s and lor whlch amroor la l r . . . anesthetic, a~~algesrc, or lranqu~lrzlng drugs were I used

E Number ot anlrnnls upon w h ~ h teachmg. experiments, research surgery or tests were c o n d u ~ l e d lnvolvtng accompanylng p a ~ n or dlslress to Ihe an~mals arbd lor whrch the use o l approprlale mesthellc, analgesic or lranqulhzlng drugs would have adversely allected the procedures, results, or mterprelatlon 01 the teachmg, research, experlmenls, surgery, or tests (An explanafron o f the procedures producrng parn or drstress rn these anrmals a n d the reasons such drugs were no1 used nlusl be aftached to thrs report)

F.

TOTAL NO OF ANIMALS

( C o l s . C + D + E)

13. O t h e r An~mals

1) Prolesslol~ally acceptable standards governlng lhe care, treatmerll, and use o l anlrnals. ~ncluding approrlille use of aneslhet~c, arialges~c, and lranqulllzlrlg drugs, prlor l o , dur l r~g. and l o l l o w l ~ ~ y aclual research, leachlng, lestlng, surgery, or exper~~ner~ ta l lo r~ were lnllowed by thlb research Iaclllly.

2) Each pr l t~c lpal lnvestlgalor has cousldered alleriiallves l o pawlul procedures

3) T l m lac l l~ l y 8s adhermy to Ihe ~ I a n d i l r d s a ~ ~ d regulallorts uncler lhe Acl. a18d 11 has requwed Ihal exceptaons l o Ihe slandards and regulallons b e spec~hed and explained by the p r r r~ .~pa l ~nveslryalor alld approved by Ihe I r ~ s t ~ l ~ ~ l ~ o r ~ a l AnllrtaI Care and Use Commlllee (IACUC) A sumnlary o f a l l s u c h excep t ions i s a t t a c h e d t o t h i s annua l reporl. III addll lon l o ~ d e n t ~ l y ~ r t y Ihe IACUC-approved excepttons, lhls sulrmary Includes d brlel expla~wl lon o l the excepllow, as well as the specles and numbel 01 a n ~ ~ r ~ a l b allected

CI.:K?'IFICA'I'ION IiY IIEAI)QUAIlTI.:S IlESEAHCII FACII.11'Y OFFICIAI. (Chief Exccutive Officer or Ixgal ly Ilesponsible Institutional Official)

I r:ertlly lhal lhe above 1s true. i:orrt!LI. albd cwnplel r (7 U S C Si!c.l~orb 2143)

S

Page 44: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I DEPARTMENT OF MED. EDUCATION I

Thls r,i,orl 1s requ~red by law (7 USC 2 \ 4 3 ] Falure l o report acrurdlng l o lhc re~u la l lo i l s call See reverse srde lor I c t ~ e r j y i ~ ~ i y HL~UI! LUIIIIIA I ~ u

r e d !I an order l o cease and deslsl a r ~ d l o be subject l o peualrles as p tov~ded lor 118 S e ~ t l o l l 2150 addllronal I r~ lo r rna l~on 0180 DOA AN

I ONE WYOMING STREET

1 3 . 7 1 ~ ~ F A C l L l N ( L ~ s l al l locat~ons where anrrnals were housed or used In aclual research, lestlrlg OH 45409

- UNITED STATES DEPARTMENT OF AGRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

I sheet5 *I Ine'essary I F A C l L l N LOCATIONS (Sdes)

1 REGISTRATION NO. I FORM APPROVED OM8 NO 0579 0036

2 HEADOUARTERS RESEARCH FACILITY (Name a n d Address as regrstered wrth U S 0 4 rnclude Zr

MNMl VALLEY HOSPITAL

sJF ANIMALS USED BY

4111mals Covered By The An~rnal

'Wellare Regulat~ons

OR UNDER CONTROL OF RE

anlrndls bemg bred. condltloned, or held tor use In t e a ~ h ~ n g leslmg, experlrnents. re5earc.h. or surgery but no1 yet used lor such purposes

I SEARCH F A C l L l N (Atldch r ~ l d r t m r ~ d sheds 11 I I C L C S S ~ ~ or use APHIS FORM 70234)

'

Number o l Number al,,lnaIs uporl E Number o l animals upon whwh leach~r lg a ~ w ~ a l s upon wh&h exper~~nerrls. expermel~ts, research surgery or tests were which leaLhlng leaching. r e s ~ a r c h conducled lllvolvlng accornpanylng p a n or dlslress research. surgery or lesls were

to the an~rnals and lor w h ~ c h Ihe use of appropr~ale

exVerlmenls Or conducted lnvolvlng anesthel~c analgesic or l ranqul l~z lny drugs would lesls were accompa~~y tng pdtn or have adversely affected Ihe procedures, results, or conducled dlstress l o Itbe arltrnals Interpretatton of Ihe leaching, research. ~ r ~ v o l v ~ r ~ g no and for which approprlJle

experlrnents, surgery, or tests (An eaplanatron 01 paln d~slress or arlehthellc allalgeslc or

the procedures producrrlg parn or drslress rn these use o l pa611- Iranqulllzlng drugs were

anrmals and the reasons such drugs were not used rel~evlng drugs used n ~ u s l b e attached to thrs report)

1 3 O t t v:r Anmals

9. N o . v h u r n a n P i l l n a t e s

10. Skcep

11. PIC%

12. O t ~ i e r Farm An~mals

I ASSURANCE STATEMENTS

1) P r ~ l ~ : s s ~ o r ~ a l l y acceplable slandards governirig I t ~ e care, lrealmenl, a r d use o l antrnals, ~ncludlng approrlate use 01 aneslhelic, analgeslc, and t r a n q u ~ l ~ z ~ n g drugs, prlor lo, d u r ~ r ~ g an(: l o l l o w ~ r ~ y aclual research, leachmg, lesllng, surgery, or expcrlrrterlletlor were lollowed by l h ~ s research l a c ~ l ~ l y .

n

n

n

n

2) Ear 1 1 f ~ r ~ r u p a l ltlvesllyalor has considered a l te r~~a l l ves l o pa111lt11 procedures

j) TIIV I ~ L I I I I ~ IS adleerlny l o the standards a8d regulallorbs under lhe ALI and 11 has requ~red thal exceptlor~s l o the s l a ~ ~ d a r d s and regulations be s p e ~ l l l e d and e x p h n e d by the pr~8,, I ~ J I lnvesllgalor a ~ ~ d approved by the III~II~IIIIU~I~~ Anur~al Care a r ~ d Use Colnrn~tlee (IACUC) A summary 01 a l l s u c h exceptions 8s a t t a c h e d t o this annua l report 111

adcl$ l~on l o r d e r ~ l ~ l y ~ n g Ihe IACUC al>proved pxrepllons lthb sulnrnary ~ r~c ludes a b r ~ e f e x ~ ~ l a ~ ~ d t l o ~ ~ o l Ihe exct?pl~ul~s, as well as the specles and numbel o l ~ I I I I I I~~~ a l l e ~ l e d

D

0

n

0

4) The d11twd11)g veleilllar6J!l Iuf It115 research lacll l ly has apl,rop#Iale author~ly l o ensure the provlslon o l adequate velermary care and l o oversee Ihe adequacy o l olher aspecls 01 a~b~t! ! ,~ l Lare aod use

CEKTIFICA'I'ION l%Y IIEAI)QUAI1'~ES ICESEAHCII PACII.II'Y OFFICIAL (Chief Executive Officer o r Legally Itcsponsible Insiituiional Official)

SIGN

I)

n n

0

APHIS fOf7M 7023 i , u,, I ){{I.' l h ' ( 1 1 n s * r ~ t t I n l t !

DATE SIGNED

*%x, w

0

0

n

0

0

0

n

0

Page 45: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I ATHENS. OH 45701 3. REPORTING FACILITY (LISI all locations where anlrnals were housed or used In aclual research, tesl. ..,. .,-".....,. -. -.., -.....-...-..-... ,. ..-.- .,. ...--- , l.,---. Atlach add~t lonal

sheets 11 t~ecessary ) 1

Thls reporl Is requlred by law (7 USC 2143) Fa~lure l o reporl ac~urd l l l y l o Ihe reguldllolls can See reverse .hie lor I I I I L ! ~ ( I L ~ Z C ~ Ne&mrl LWIIIIII IJu

resull an order l o cease and deslsl and l o be subjecl to per~al t~es as provlded lor III Secllor~ 2150 addllronal I. lo rmd l~on 0 180 DOA AN

I I FACILITY LOCATIONS (Srtes)

I

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

. .

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

Animal Research Bui ld ing I

1 REGISTRATION N O I FORM APPROVED

31-R-0082 OMB NO 0579.0036

2 HEADO~~ARTFR+ RFCEARCH FACtl I N fNnma and A d d r e w nc ranlslered wrth USDSU rnclur

Id

OHIO UNIVERSITY DEC - 5 2 L DEPT. OF LABORATORY ANIMAL RES

085 GROSVENOR HALL

Grosvenor H a l l

REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILIPI (Aflach d d r t l r l ~ n ~ ~ d l S ~ I U P ~ S I I I I ~ ~ L I ' S S ~ ~ or use APHl FORM 7023A) '

A I B Number 01 I c Number 01 I D M,,.n,.ur ,%, ,.,,,.,, ,- .,,.,, I E Nurnbet 01 ~ n l r 11s upon which leaching. I F

dr~rrr~ats upon wh~ch leach l~q . resed~ch. experlmenls. or lesls were conducted

An~rnals Covered By The Anlmdi

Weflare Reguldllons

- ..".'.",.' .,. -...,..-,_. "IIU.. whlch experllrlenls. teachlng, research. surgery, or lesls were conducted ~ ~ i v u l v l n g accornpanylng p a n or ,i,~l,c.cc I,, t h n :...am ..I<

an~rnals bemg bred coi~drtloned or held lor use ~n leach~ng, leslfng. experlrner,ts,

rxpermenls, rc ,lSarch, surgery or tests were c o ~ ~ d u ~ l e d IIIV~IIIII~ accompdrrylng paln or d~slress l o Ihe dmrnals 110d lor whlch Ihe use o l epproprlate jnest hellc, an; i jes lc or I ranqu~ l~z lng drugs would hdve adversely .illected the procedures, resulls, or lr~lerprelatlon I t the teachlng. research.

TOTAL NO OF ANIMALS

research. or ,- ,,,- "....,,-.-

~ n v o l v ~ n g ~ l o and lor which approprldle experlrnents, s Irgery, or tests (An explanalron o l surgery bu l nol pam, d~slress, or anesthellc, al,algeslc, or the procedure r~roducrrry parn or distress m lhese ye1 used lor such use of pain. lrarlqulllllng drugs were anrrnals a n d tt c reasons such drugs were not used 1 P o I e l ~ e v t n g drugs / us..( nlust b e ansc l ed l o I h ~ s report)

4 Dogs

5 C a t s

6 Gumea PIQS

7. H a m s t e r s

8 Rabbits

0

6

9 Non-human P r ~ m a t e s

10. Sheep

. 11. P~as

12. O t h e r Farm An~mals

13 O t h e r An~mals

I -. .

1) Proless~onally acceptable standards governing the care. Irealmenl, and use o l anllnals. ~ l r c l u d ~ n g approitate use o l anestheli. .. ilnalgeslc, and t r a n q u ~ l ~ z ~ r i g drugs, prlor to, dur l r~g. and tollowmy actual research, teach~ng, tebtlng, surgery, or exper~lr ler l lo t~or~ were Id lowed by t h ~ s research l a c ~ l ~ t y

0 0

0 0

0

463

0

0

0

0

0

V i r g i n i a Opossum

Dwarf Opossum

G e r b i l s

2) Each prlieclpal mvesllyator has ~ons ldered allerrmllves l o pa l~ l lu l procedures

0 0

0 2 19

0 0

3) T Im f a c ~ h l y IS edherlriy l o the sl i lndords and regu la l lo~~s under Ihe Acl. and 11 has requ~red lha l exceptsons l o the standards a ! ~ d regula l~ons be specllled and explained by the p r ~ n c ~ p a l ~nvesl lgalor a ~ i d approved by Ihe Ins l i lu l lo l~al Anllnal Care a l ld Use Colnun~llee (IACUC) A sumnlary of a l l s u c h e r c e p l i o n s i s a t t a c h e d t o t h i s annua l r e p o d . III a d d ~ t ~ o n t o lder~ll lylrrg the IACUC.dt~proved exceptlolls, lhls sulrbnaary lircludes a brlel explalrallon o l Ihe excepllolrs. as well a; l t ~ e specles and number of anlrndls a l lec led

ASSURANCE STATEMENTS

0

35

62

4) Tlw dllerldl l lg velerltldrlilII tor Illla tesedlch l a ~ l l l t y has dpl~lopt ld le dulhorl ly l o ensure the provlslotl o l adequdle velerlndry c.ire and l o oversee Ihe adequacy o l other aapucls 01 d!wrrdl cdre a ~ ~ d use

0 5

5 17

0 3

CEHI'IFICA'I'ION R l I 1 k:AI)QUAH'I'k:S ItESEARCII FACII.11'Y (I YFICIAI. (Chief Executive Officer o r Legally Iteaponsiblc InstiiuLional Oll icial)

I (er l l ly lhdl the dbuve 15 trl lr, r t l r r r c l dl ld (wlbpletr (7 U S C St.< l lon 2143)

I I A P H I S tOf41.' 7073

I -4. ;,, , . ~ va I ,;>I.< ( e 2 ; T F,?, ,.rat! IN I', , m , , , k . ~ t

IAIJG $ 1 t

DATE SIGNED

Page 46: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

CONTINUATION SHEET FOR ANNUAL REPORT OF RESEARCH FACILITY

( TYPE OR PRINT)

- 3 E P G R T CF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACIL IN I!

an~rnal, r i c i , j L - .I!.. '1. . - 1 D r r J 5 , The 4!11111dI LOIIIJIIILI:CJ VI

w r t l ~ n e R u q u l a t ~ o r , ~ held lbr use in I rdLhinJ I s ~ I n , ] rxper lments ,?5,, ,*, . , > r

. - - - - - - - - - - - - - - - - - - surgery bUl ,,,,I

12 3 OR 13 G l t ie r ' , I f;,,'h

( h s r by spec.esi purpose,

Bats 19 0

Red Squirrels 0 12 - - -

Flying Squirrels 0 13

Chipmunks 0 15

Dormouse 0 2

2 HUDOUARTERS RESEARCH F A C I L I N INdrne and AJ~lre:s ds regrslored r r f h US04 I j r t ~ t,,ie :tp COLIC, OHIO UNIVERSITY

DEPT. OF LABORATORY ANIMAL RESOCRCES 085 GROSVEXOR HALL ATHENS, OH 45701-2992 1 '

STATUS: ACTIVE

- -

espertmrnls, research, surgery or t e s ~ s i e r e conducled lnvolvlny accolnpdnytrrg p a n or dtslress l o Ine an1rn31s and lor r h l c h the use 01 appfopr8ale ane>i"eltt- 1.. ~I,:+S.!,' or l r ~ n q u o l ~ z ~ n g druys would have d i e r s r l y a l l e i l e d Ihe procedures, results. or ~ n l e r p r e l a l ~ o n o l !he leachtng. research. exper8menls. suryrry, or les ls (An o ~ p l d n d l r o n ol the procedures producrng pall1 or dlslress In lhsse d,,imals .+nd :he redsons such drugs were no1 used must be af lached lo thrs report)

I A S i L R A N C E STATEMENTS

I 1) Proless~onal ly ncceplable slandards governmg Ihe cafe. Irealmenl. and use 01 al~ l inals. l nc lud~ng approitale use o l aneslhrl!c. analges~c, and l ranqudlr lng drugs. prlor to, durlng,

and lo l lowlng acludl research, Ieachmg, lesllng. surgery. or experllnenlJllOn were lol lowed by lh ls reseatch lac t l~ ty

2 ) Each prlnclpal mvesl lgalor has considered allernaltves l o pa~rr lu l p rwedures

3) T h ~ s lacll l ty 1s adhermg l o the slandards and regula l~ons under Ihe Act. and II has requared lha l rxcepl lons l o I h r slandards and reyulallons be s p e c ~ l ~ e d 2nd explalnrd by Ihe prxrrc~col lnvesllgalor and approved by the l r ~ s l t t u t l o ~ ~ a l A ~ r m i l l Care and Use Colnlnlltee ( b C U C l A summary o f a l l s u c h e x c e p t i o n s i s a t t a c h e d l o l h l s a n n u a l repor( In hL'31l1on l o tdenl l ly lng Ihe IACUC-approved rxcrpl tons, lh ls sumlnary includes a b r ~ r l eXplanJl10n o l Ihe axcepl~oats. wr l l ds Ihe spccj rs JOJ i l u m c l r 01 dtrimdls a l lec led

4) r t l d a l lend lng r e l e r * ~ ~ d r l a l ~ lor l h ~ s research l a c ~ l ~ l y has approprlale a u l h o r ~ l y l o ellsure Ihe p r o v ~ s ~ o n o l a ~ l e q u ~ l e verereojry care and l o overber I h r adeqilJCy o l other JSLei l r 21 antmal care and use

CE,HTIFICATION BY 11EADQUARTES RESEARCH FACILITY OFFICIAL (Chief Execut ive Officer o r Legally Responsible Institutional Official)

I c e r l ~ l y lha l Ihe above 1s Irue. correcl , atld complele (7 U S C Seclton 2143)

SIGNATUR DATE SIGNED

Page 47: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

4 D O ~ 14 24

5 C a t s 12 2 1

6 Gu~nca P12s 8 8

7 H a m . z l e r s

8 R h b b t t s 7 7

9 Non.hunian P r l n i a l e s

Union Hall Room 022

1 0 Sheep

1 1 . Pias

--

12 O t h e r F a r m A m m a t s

13 O t l ~ e r Antnials

4) l l w d l l r l ld l l lQ v e l r t ~ m t ~ ~ c d ~ ~ 101 1111) I C . ~ C L I X C ~ IJLI~IY h i l b d p l ) ~ U p ~ l i l l P a u l h u ~ ~ l y 10 e @ l b U l e Ihe p!ovlslol l u l i ldequii le velertndry Late a!,d l o oversee I he adequacy o l orher aspec l s o l w w e l L i l w m d use

CL: It'I'IFICA'I'IOK 131' IIEA1)QUA HTES RESEAHCIi FACII.II'Y OYYICIAI. (Chief Ezccut iw OI'ficer or Legall>, I l c ~ p o n s i b l r Institutionnl Oflicial)

I I:rr l l ly rtaal the abcwr ts Ieue. t : l > r r f v l . ,md c~ ,~ lbp l r l e (7 U S C Set:l,nn 2143)

SIGNClURE OF C.E.O. OR INSJl lU l IONLL OFFICIAL ,dt~lJ DATE SIGNED

Page 48: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Comparative Medicine Unit

See reverse slde lor Th~s r 3ulre.j b y law (7 USC 2143) Fa~lure l o reporl according l o !lie regu la l~o~ ls call

addlllonal In lo rmd l~on 0180 DOA-AN result , 0 cease and destsl and l o be sub~ec l l o penallles as provlded lor III Secllon 2150

- - UNITED STATES DEPARTMENT OF AGRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

* . -- ANNUAL REPORT OF RESEARCH FACILITY

(TYPE OR PRINT)

1 REGISTRATION NO. I FORM APPROVED

31-R-0092 O M 0 NO 0579-0036 ' - ----.--.. -.-.a .-. *...-- ^ _ A A,.,._^^ ̂ ... .̂"...,.,,+,.,Wrth "SO&

'''Iude Lp 31-R-0092, Cust Id 255

NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF L 4209 STATE ROUTE 44

P 0 BOX 95

ROOTSTOWN, OH 44272 I

I

3 REPORTING FACILITY (Llsl all localrons where anlmals were housed or used In a ~ t u a l research. Ies11ng. leachlng or exper~mer~tal~on, or nelo lor lnese purpusas nr tach a d d l l l ~ l l ~ l sheels 11 llecessary ) -

FACIL IN LOCATIONS (Srles)

A

Anlmdls Covered BY The Arblrndl

Wellare Regulal~ons

- -

4 Dogs

5 C a t s

6 Gumea P ~ g s

7 H a m s t e r s

8 R a b b ~ t s

9 N o n - h u m a n P r ~ r i i a t e s

lo. Sheep

11 Plas

12 O t h e r Farm An~rnals

13 O t h e r An~mals

Bats 1 52

I IREPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Attach ad~drt~nrral sheets 11 tlecessan. or use APHIS FORM 7023A)

'

B Number o l an~mals being bred, ~ o n d ~ t ~ o r ~ e d , or held for use ~n leachmg lestlng. expellmenls. resear~h, or surgery but not ye1 used lor such purposes

4

2

0

0

0

0

0

0

0

0

0

F.

TOTAL NO OF A N ~ M A L ~

( ~ 0 1 s . C + D + E)

Ferrets

1) Pruless~or~ally acceptable standards governmg l t ~ e care, ttealment, and use o l anlmals. ~ n c l u d ~ n g appror~ale use o l aneslhellc, analgeslc, and tranqulllzlng drugs, proor to, durmg. aud lo l low~r lg aclual research, leachmg, lesllng, suryery, or erperlrrterltallon were lnllowed by Ihls research Iacl l~ty.

E. Number o l an~mals upon whlch leaching. experlmenls. research, surgery or tesls were conducled involving accompanylng p a n or d~scress l o the an~mals and lor whlch the use o l appropriate anesthetic, analgeslc, or l ranqul l~z lng drugs would have adversely a l lec led Ihe procedures, results, or Interpretallon of the leachlng, research. exper~rnen~s. surgery, or tesls (An explanation 01 the procedures producrny pain or drstress rn these animals and the reasons such drugs were not used nwst b e atiached to thrs report).

C Number o l a~tlrrlals upon which leaLhlng, rebearch. experlmenls, Or

lesls were conducled ~ r tvo lv~ng no paan, distress, or use o l pall>. reltev~ng drugs

0

Gerbils

2 ) Each pr l l lc~pal wvesllyalor has considered alterrlallves l o pa l~ l lu l procedures

- -

-

-

-

-

-

-

-

-

-

-

0 Nulnber a,,llnalb whlch experllikerlls. leachlng, resear~h. surgery, or lebls were conducled ~nvulv lng accompanylng paan or dlslress 10 lhe anlmals and lor which approprlale aneslhellc, a,lalgeslc, or lrallqulllllng drugs were used

I

0

3) Th~s taol l ty IS adtoermg l o the slandards and r e g u l a t ~ o ~ ~ s under the Acl, and 11 has reclu~red that exceptions l o the standards and regulallons be spec~l led and explained by the pr lnc~pal ~nveslagalor a ~ l d approved by Ihe l n s l ~ l ~ ~ t ~ o l d Ari i~rmI Care and Use Colnmlllee (IACUC) A sumnlary o f a l l s u c h e x c e p t i o n s i s a t t a c h e d to t h i s annua l repor l . III adll l l lon l o l d e n l ~ l y ~ r ~ g Ihe IACUC.approved exceplinns, t h h sulnnbary ~ncludes d brlel exp la~~a l lon o l ltle excepllons. as well as the specles and numbel o l anlrnals dflecled

-

-

-

-

-

-

-

-

-

-

-

-

-

- - ASSURANCE STATEMENTS

4) The dllt:rtr l~l~g VelellllJllJli tor 1h15 research l a c ~ l ~ l y has apj)ropllale ~ u t h o r l l y l o e11su1e Ihc ~~OVIS IO I I 01 adequate velermary care and l o oversee Ihe adequacy o f other aspucls o l anwrtal 'are anld use

--

CEItTIFICA'I'ION H Y IIEAI)QUAltT1.:S RESEAKC11 FACII.11'Y OPPICIAI, (Chief Execut ive Officer o r Legall) ftesponsiblc Institutional Oflicial)

I c t r l l l y l hd l the atnlve Is tr l lr. c clrrr.< I alld L~)n~p Ie le (7 U S C SPL 11nrb 2143)

SIGN I DATE SIGNED

\ r /24 /r

A P H I S FORM 7 0 2 3 A + , 9 V t t t < t v t It 23 I .I( 1 t b , ,,IS t t c obS, I, I, 1

I k U G 91)

Page 49: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I REPORT OF ANIMALS USED BY (

7 , , , > , , , , , , , , ,,., :,,,,.> ;,, ,,,*, ,- ' .o,, I , , 8 ,,, r 4, ,r 1 4 , ) ' , 8 f 8 , , * . t t d , l 4 8 ' , 8 21, _ , a I / . I , ' . I . a , . , I

,&It (1, a,8 ,,,,lP, 1" p',d>,: ,,,*,I ",.,I51 " 8 d I t , I # ? W L q W I I<, ~,,!',.,ll,eL. d,. pl>"8<It.,J I<>! (1, 53 I>U,. " I 5 d , d < i ~ l ~ o ~ ~ a l ~ ~ ~ I u ~ ~ T I c ~ I I u ~ ~ L Ztlb CjCL - ? J of'

An~mals Covered By The Anmal

Wellare Regulalions

- UNITED STATES DEPARTMENT OF AGRICULlilRE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

. .

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

JAN 2 9 2001

4. Dogs

1 REGISTRATION NO. I FORM APPHClVED

3,- R- ec,ciq OMB NO 0579-0038 I

2. HEADOUDOTCDQ DCCFARCH FACILITY (Narne and Address. ds roy~siared r ~ l h US& ~ r ~ c l u d e Z

MERIDIAN DIAGNOSTICS, INC. 3471 RIVER HILLS DRIVE CINCINNATI, OH 4 % ~

5. Cats

6. Gu~nea P~gs

3. REPORTING FAClL lN (L~st all localions where anrmals were housed or used in aclual research, lesting, teamww, -,....-.-..-..-... -. . . . . tach addll~onal

sheels il necessary.)

FAClLlN LOCATIONS (Srtes)

SEE A-r rn tKcb I

7. Hamslers

8. R a b b ~ t s

9. Non-human Pr ima les

10. Sheep

12. Other F a r m Animals

Go&", 13. Other Animals

0. Number 01 animals being bred. cond~lioned, or held lor use in leaching. lesling. experiments. research. or surgery bul no1 yet used lor such purposes.

I

UNDER CONTROL OF RESEARCH FAClLlN (Attach atlidikonal shoels 11 necessary or use APHIS FORM 702%) '

3) Th~s I a c ~ l ~ l y IS adhermy to Ihe slandards and regulatlol~s under the Act, and 11 has requlred that exceploorls l o the slar~dards and regulal~ons be spec~hed and expla~ned by Ihe p , l~ l~ :~pa l lnvesllgalor and approved by the l n s l ~ t ~ ~ l ~ o r ~ a l An1111a1 Care and Use Cotnmltee (IACUCI A sumnlary o l al l such excepl ions i s a l lached l o th is annual reporl. 111 addrllon lo rdenlily~rlg the IACUC-approved nxceplions, lhls sulrlnbaty includes a brrel explanallon o l the exceptions. as well as Ihe specles and number o l a n i ~ ~ ~ ~ l a allected

- 37 -

-

--

--

--

- --

--

- --

- --

--

-

-

ASSUFIANCE STATEMENTS

4) Tl,e JII~IWJI~~Q velerlnorrart lor 1111s reaedrch laclllly has app:opllale dulhorlly to ensure the pruvrslo~~ ol adequole velerlnory care and l o oversee Ihe adequacy u l other aspeclb o l ~IIIIIIJI care a11d use

CEHTIFICA'I'ION ISY 1IEAI)QUAH'rES RESEAHCI1 YACII.ITY OVFICIAI. (Chief Executive Officer or Ixgally Responsible Institutional Ofncial)

I cerllly Ihal the above is trlre, corratcl. and ccrtnplele (7 U S C S+!c:tlnn 2143)

F.

TOT^^ NO, OF

(cots. c + D + E)

I

-

-

-

-

-

-

-

-

- - -

-

-

-

-

-

-

- -

-

I

E. Number ol animals upon which leaching. experiments. research, surgery or tesls were conducled involving accompanying pain or dislress l o Ihe animals and lor which the use of appropriale anesthetic, analgesic, or lranquillzlng drugs would have adversely affected the procedures, resulls, or interpretation ol Ihe leaching, research. experiments, surgery, or tests. (An explanalion of the procedures p r o d u c i ~ g parn or ddress in these animals and the reasons such drugs were no1 used nwst be attached to lhrs report).

C Number o l an~mals upon whrch leaching- research. experlmenls, Or

tests were conducled rnvotv~ng no pan. drstress, 01 use ot parn- relievrng drugs.

I ) Proless~onally acceptable slandards governing the care trea~rnenl. dnd use 01 animals, n~cludmg dpprormle use 01 aneslhelrc, analgesrc, and lranqul l lz~r~g drugs, prror lo, durrng. and l o l l o w ~ ~ ~ y actual research, teaching, teallng, suryery, or experomentatron were lollowed by lhra resedrch lacr l~ly

2) Each p r m ~ ~ p a l ~~ivesIIgaIut has considered allernalrves to palrblul procedures

v

A P H

IS

0, Nuln,,,,r ul alllrnals upon wh~ch experirr~enls. teaching, research. surgery. or tesls were conducled rrivolving accompanyrng pain or d~stress to the a~rrrnals and lor which

a,lalgesic, or lra,,quil,ring drugs were used

k- (AUG 91)

DATE SIGNED

4#f

Page 50: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

Liceneee/2ey;ie=ra,?t Meridian Diaqnos t ics , I n c .

l e a s e 'is; b e l o u a l l s i z e s ~ h a i h o u s e r e g u l l z e d a n 3 z l s u .cez ;be above n l ; w e = . .e

sc.-e t o i n c l u d e = e p e s = e o intorma:io% i f ;he L i n e d o e s nor apply, p l e a s e x,a=::

it ti/;. :f you h a v e more r n a n rhree ( 3 ) s i z e . c o w =his f ozm zs many ;imes a s n e e d e d before fillinc i n t h e sites-

Size N o . : 1 ~ame/Depa:tmenZ: Clerc0

A a c = e s s : 3858 Debby Carol D r i v e

C i n c i n n a t i , OH 45245 (County: Hamilton)

E-iltinc: Meridian gildi in^

f loor /i?oom:

C o n t z c z ?ezson: -------- ----- -----------------

S i z e N O . : 2 Name/De~az:nenZ: Snowhill Breedinq Kennels

A d c z e s s : 3051 Snowhill Road

West Harr i son , I N 47060 (County: Dearborn)

. . . =.:,l=:nc:

- - - 8 - ,c=z/?.3cz:

==:=z=: 7 5 = e = : : --- - - - - - - - - - ----- - -----------------

All redactions on this page are pursuant to (b)(6) & (b)(7)(c).

Page 51: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

See reverse slde lor This report s requlrrd by law (7 USC 21 431 Fdilure l o ueporl Jcturdll ly l o Ihe r r g u l a l ~ o t ~ s call res,,;~ ~n an order 10 cease and desist and l o be subjecl l o per~a l l~es as provlded lor III Secllon 2150 a d d ~ l ~ o r ~ a l l n l o r r n d l l ~ n 01 80-DOA AN

UNITED STATES DEPARTMENT OF AGRICULTURE 1 REGISTRATION NO. I FORM APPROVED ANIMAL AND PLANT HEALTH INSPECTION SERVICE O M 6 NO 0579-0036

. .

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

CENTER FOR RESEARCH OF ENDANGERED WILD.

3400 VINE STREET

CINCINNATI, OH 45220 I I

3. REPORTING FACIL IN (LISI all locallons where animals were housed or used In aclual research, testing, leachlng, or experlmenlalloll. or neto lor lnese purposes n l t d c n ddd1110naI

sheels 11 tlecessary )

FACIL IN LOCATIONS (Srles)

Cincinnati Zoo and Botanical Garden I

1 R F D n R T n F ANIMAI 5 LlSED BV OR UNDER CONTROL OF RESEARCH FAClLlrY IAItach ~ ~ l ~ d ~ t ~ n ~ l a l sheets r l !lecessaN or use APHIS FORM 702%) ' , . - . - . . . - . . . . . . . . . . . - - - - - - - . - - . - - - - . - - . - . -

I expertmenls. conducled research, or ~ ~ ~ v u l v ~ n g rlo surgery bu l not pain, dlslress, or ye! used lor such use o l ~JIII-

purposes reliev~ng drugs

11 Plos

12 O l h e r F a r m A n i m a l s

F.

TOT^^ OF

A

ArblrndI*, Covered By The Atbtmal

Wellare Reyulal~ons

4. Dogs

5. Cats

6. Gulnea P ~ g s

7. H a m s t e r s

8. Rabb~ls

9. Non-human P r m a l e s

10. Sheep

13. O l h e r An~mals

ASSURANCE STATEMENTS

I ) P ro less~o~~a l l y acceplable standards aovernlnu Ihe care, lreollnenl. and use 01 anlrnals. mcludma dourortale use 01 aneslhetlc. analaes~c. and t r a n o u ~ l ~ z ~ n a druas. Drlor lo. durma.

"..~".",,~","'., ,,".., ", dlhlress l o I t ~ e m ~ ~ r n d l s and lor which approprlJle aneslhellc, allalgeslc or lrallqulllrlng drugs were used

- . . . - . and l o l l o w ~ r ~ y acludl research, leachlng, leslmg. suryery, or e x p e r ~ ~ r ~ e r ~ l ~ t l o r ~ were lol lowed by this rebedr~h l a ~ ~ l ~ l y

B Number o l anmals b a n g bred, cond~ltoned, or held lor use ~n leachmg, l e ~ l l l l g

2 6

2) Each prlnclpal Invebllyalor has cotlsldered allernaltves l o p d ~ t t l ~ l procedures

lnlerprelalton o l the teachmg, research. experrmenls, surgery. or tesls (An explanalron of the procedures producrrly parn or drslress rn these anmals and Ihe reasons such drugs were no1 used musl be attached to thrs report)

3) T l m IJLI~IIY 15 a d l w t n y l o Ihe stdnddrds and rcgulaltona uwler the ALI aud 11 t ~ s requ~red lhal exceptboos 10 the stnnddrds and regula l~ons be s p e d t e i l and expldlfned by Ihe p r m pal ~nveal lyalor a ~ ~ d approved by Ihe l n s l i l ~ ~ l l o ~ ~ d l AIIIII~JI Cafe J I ~ Use Cumln~ l tee (IACUC) A summary o l a l l s u c h e x c e p l l o n s IS a t l a c h e d l o 1h1s a n n u a l r e p o r t III a d d ~ l ~ o n l o 1de!!Illy118g Ihe IACUC dpproved rxwp l ln l l s lhls hu!rln~dry ulcludes d b r ~ e l explJlldllor~ o l Ihe excepllons as well ds the specles and numbel 01 JIIIII~J~~ dl lec led

C Number o l d o ~ ~ r m l s upon wh'ch leachln'J resed~ch. exper"nen's, Or

tests were

(&IS c + D + E)

10

4) Ttbc ~ l l r ~ ~ d t ~ n y velcrltldrldll lor l l l lb re~edrch f d ~ l l l l y hJb JIqI~u1~ftdIC ~ u l h o r l l y l o ellsure Ihc: p r u v l ~ l o n 01 ddcqudle velerlndry LJIC J I ~ 10 Oversee Ihe Jdec(ud~y 01 oltler a s p e ~ l a 01 d l l l l I l ~ l Cdre dlld Llhe

D Nulnber ol a,,llnalb upon w h ~ c h e x p e r ~ ~ ~ ~ e n l s , leaching, research. surgery, or lesls were c o ~ ~ d u c l r d ~ l ~ v o l v ~ n g 3,.,.-.-,%7..%.,n- -2.m -,

5 1

DATE SIGNED

11/01/00 L

E. Number u l anlrnals upon whlch leaching. experiments, research, surgery or les ls were conducled ~ ~ ~ v o l v l n g accornpanylng paln or dtslress l o (he an~mals and lor whlch !he use o l approprlale aneslhel~c. analgeslc, or lranqull lzlng drugs would have adversely a l lec led Ihe procedures, resulls, or

6 3

CEH'I'IFICA'l'lON 1)Y 1IKAI)QUAH'I'k:S III.:SEAHCIi FACII.11'Y O F F I C I A I . (Chief Executivc Off icer o r I.egally I tesponsil~le Institutional 0l l ici . i l )

I I e r l ~ l y lhdl l l w dbllve IS l r lw 1 r ~ r r r - ~ l JIKI 11~111&3181? (7 U S C SW 11nr1 2143)

SIGNA

A e H 1 5 1, d.4 i L J > @ o ' h i ) i r I <

A J , 1

Page 52: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

T:;ls reporl IS requlred by law 17 USC 2143) Fa~lure l o reporl accordllly l u Ihe regulallollh Call See reverse s ~ d e lor 1,,1er',,&!,,< hcLj,,,1 L,,,,l,Wt Id.,

resull rn an order l o cease and des~s l and l o be sub~ec l to penalt~es as provlded lor III Secllon 2150. add~l lonal ~nlormal lon. 01 80.DOA-AN

--

4. Dogs I

UNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

7 28L . . 4 '

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

I

5. Cats I

V ' 1. REGISTRATION NO. FORM APPROVED

OMB NO 0579-0036

'!2. HEADo"ARTERs RE5EARCH FACILITY Warne ! d r p c n= . - - r e d w ~ I h US., ! mclude 7

31-R-9102, Cust Id 259

AKRON GENERAL MEDICAL CENTER

400 WABASH AVENUE

AKRON. OH 44307

A

Ammals Covered By The Anlmal

Wellare Reyulal~ons

9. Non-human P r ~ r n a l e s

10. Shee

3. REPORTING FACILITY (LISI all locations where anlmals were housed or used In actual resedrch, teslanh . . .-. ...,, , ,U,rv.ro ~ l t a c h addltlonal sheels 11 llecessdry )

FACILITY LOCATIONS (S~fes)

I

B Number 01 anrrnals belng bred. cond~ltoned, or held lor use ~n t e ~ c h l n y lesllng, experlments. research or surgery but no1 yet used lor such purposes

12. O t h e r F a r m An~mals

ASSURANCE STATEMENTS

1) Proless~onally acceptable standards governing the care. lreattnenl. and use 01 annnals. ~ n c l u d ~ n g approrrate use o l anesthetic, analgeslc, and Iranqu~lrzlng drugs, prior lo, durmg, and tollowlr~y actual research, leachlny, tesllng, surgery, or experlrnerllsl~on were lallowed by thls research lac~ l l l y

I

1 REPORT OF ANIMALS USED BY OR UNDER CONTROL OF RESEARCH FACILITY (Aliach adr~lrlrorial sheets r l necessary or use APHIS FORM 7 0 ? X ) '

2 ) Each p r ~ l ~ c ~ p a l ~nveslryalor has ~:ons~dered allernallves l o palnlul procedures

3) T h ~ s l a ~ ~ l ~ t y IS adher~ny l o the standdrds and regula l lo l~s under !he Acl . and 11 has requ~red thal excepllons l o the s t a ~ ~ d a r d s and regulallons be s p e c ~ l ~ e d and explamed by !he pr~nclpal Inveslryalor and approved by the Ins l l l u l ro~~a l Arr l~r~al Care and Use Comm~tlee (IACUC) A summary 01 a l l s u c h e x c e p t i o n s is a t t a c h e d l o t h i s annua l report. III addlllon to rdenl~ly~rtg the IACUC-approved nxcepllnns, thls sulrlmary Includes a brlel explanallon o l Ihe excrpllons, as well as Ihe specles and number 01 ar11111dIs allecled

F.

TOTAL NO OF A N l ~ A ~ s

(~01s . c + D + E)

4) Ttw d l l t ! f d ~ ~ ~ g velerl8bdrldII 101 ltlls resedlch I d ~ l I l I y has dpiLr0pIIJle dul t lor~ly to ensule Iho provlslull o l adequdle velerlllary a r e and l o oversee the adequacy o l olher aspecls ot a!811r1dI care aud use

-

-

-

-

-

-

-

-

-

-

-

-

-

-

I

E. Number of anlrnals upon whlch teaching. experrmenls, research, surgery or tests were conducled ~nvolv lng accompanylng paln or dlslress l o the anlmals and lor whlch lhe use o l appropriate aneslhelrc, analgeslc, or lrar~qurl lzlng drugs would have adversely a l lec led the procedures, resulls, or lrrlerprelatlon o l Ihe teachmg, research. exper~ments, surgery, or les ls (An explanatron 01 the procedures p roducr r~g parn or drstress rn these anrmals a n d the reasons such drugs were not used n w s l b e attached to thrs report).

C Number 01 dr~~rnals upon which leact'lng@ research. experlmenls, Or

tests were conducted ~ n v o l v ~ n g no patn, distress, or use o l Pam- relievmg drugs.

0. Nulnber a,lllnals upon whlch e x p e r ~ ~ ~ ~ e l r l s . teach~ng, research. surgery, or lesls were conducled ~ n v u l v ~ n y accompanylng p a n or d~ztress l o Ihe alblmdls and lor which appropriate aneslhellc, al,dlyeslc, or Irallqulllrlng drugs were ,,,,,,

CEHI'IPICA'I'ION I%Y IIEADQUAK'rl*:S RESEARCH I.'ACII.II'Y OPPICIAI. (Chief Execut ive Officer or Legally Ilesponsiblc Institutional Oflicial)

I c:erllly thal the d b w e IS Irus. corrc?cl. a~bd co~r~p le l t . (7 U S C S1!(.11011 2143)

S

A P H I S 7 0 2 3 , - , t ~ t ~ l 8 2 2 KCI * r ~ # , \ ,)t,~,,,l,,l,,

.ti13 5 1 )

DATE SIGNED

/ - / - / I C j Bc-

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This repm is required by law (7 USC 2143). Failure to report according to the regulations ---

See attached form foc additional Information

Interagency ~ e p o 4.: UNITED STATES DEPARTMENT OF AGRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT OF RESEARCH FACILIlY ( TYPE OR PRINT )

I 1. CERTIFICATE NUMBER: 31 -~-0104 I FORM APP~OVED OMB NO. 05790036

CUSTOMER NUMBER: 260

L C A-Vision Inc. Laser Centers Of America 7840 Montgomery Road Cincinnati, OH 45236

Telephone: (51 3) -792-9292

3. REPORTING FACILITY ( List all locations where animals were housed or used in actual research, testhg. or experimentalion. or held fw these purposes. Attach additional sheets fl m r y ) 1 FACILITY LOCATIONS ( Sites ) - See Atached Listing

I REPORT OF ANIMALS l lSED BY OR IlNOEF

Animals Covered By The Animal

Welfare Regulations

8. Number of animals belng bred. mditioned, or held for use in leach~ng. testing. experiments.

research, or surgery but not yc

I

4. Dogs I

5. Cats 1 I

6. Guinea Pigs ! 7 Hamsters I

8 Rabb~ts I

- -

9 Non-human Pnmate I

-- - -, . - - - - - -

10 Sheep I

- -- 11 Pigs , -- - - 12. Other F a n An~mals 1 - -

1

13. Other Animals 1 .- -

i

ASSURANCE STATEMENTS

1 ) Professionally acceptable standards governing the care, treatment. and use of animals, lnduding appropriate use of anestetic, analges~c. and Iran~u~liring dmgs. prior to, during. and follmng actual research, teachmg, testmg, surgery, or expenmentation were followed by this research faulity.

INTROL OF RESEARCH FACILITY I Anach additional sheets if necesuru o r use APHIS Fo rm 7023A \ I

2) Each pnnc~pal lnvestigalor has considered alternatives to painful procedures

C. Number of animals upon which teaching. research. experiments, or tests were mducted indnng no pain, distrass. or use of pain- rdievinq dmgs.

3) Th~s factltty IS adhenng to the standards and regulaBons under the Act. and ~t has requ~red that eXCepttW to the standards and regulab0nS be specfied and explained by the pnnupal lnvestlgalor and approved by the tnst~tut~onal Anmat Care and Use Committee (IACUC). A summary of all such exceptions IS altachsd l o tha annual report In addmon lo ldenMylng the IACUC-approved excepttons. lh~s summary ~ncludes a bnd explanallon of the excepttons, as well as the spectes and number of annals affected

4) The anendlng vetennanan for this research factlity has appropriate authonty lo ensure Me provision of adequate vetennary care and to oversee the adequacy of other aspects of an~mal care and

CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL

D. Number of animals upon which experiments, teaching. research, surgery, or tests were conducted involving accompanying pain or disVcss to Me animals and for which appropriate anesthetic. a

I SI IDATE SIGNED I

E. Number of animals upon which teaching. experiments. research, surgery or tests were conducted indving accompanying pain or distress to the animals and for which the use of appropriate

TOTAL NUMBER

anesthetic, analgestc. or tranquilizing dmgs would / OF ANIMALS

have adversely affected the procedures, results. or interprelatian of the teachtng, research. experiments, ( COLUMNS surgery, or tests. ( An explanation of the procedures C + D + E ) pmduung paln or distress ~n these antmals and the reasons such dmgs were not used must be anached to I

I

6 FORM 18-23 (OCT 88). which is obsolete.

Page 54: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

I --------------- ----------------- ANNUAL REPORT OF RESEARCH FACILITY OBERLIN COLLEGE

(TYPE OR PRINT) nl

70 N. PROFESSOR ST.

See reverse s ~ d e lor l ~ t l r r j y e , i ~ y HLCU)CI LUIIIIUI NU Thds revorl IS required b y law (7 USC 2143) Fa~lure l o reporl accordlny l o I11e regulalrorlb can result In an order ( 0 cease and deslst and l o be sublecl to penall~es as p rov~ded lor 111 Secllon 2150 a d d ~ t ~ o n a l tnlormalron

0180 DOA AN i\

I OBERLIN, OH 44074

UNITED STATES DEPARTMENT O F AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

, ..

I 1 3. REPORTING F A C l L l N (Llsl all locallons where an~mals were housed or used In actual research, lesllng, leaching, or experlmerllatoon. or nela lor lnese purposes Attach addlllonal

1 REGISTRATION NO. I FORM APPROVED

31-R-0112 OMB NO 0579-0036 ---- - - --- ' --. , " ,." '"' "' - . " ".- -'

Sperry Animal F a c i l i t y , 130 W . L o r a i n S t . I O b e r l i n , OH 44074-1082 1

e&

K e t t e r i n g H a l l of S c i e n c e , 130 W. L o r a i n S t . I

. ,

O b e r l i n , OH 44074-1082 !REPORT OF ANIMALS USED BY OR UNDER CONTROL

-- -- - qtered wrth US04 ~ n c l u o --------------- ------- --- -------

Anrrnals Covered By The An~inaI

Wellare Regulal~ons

B Number of an~rnals b e ~ n g bred. ~ u r ~ d r t ~ o n e d , or held lor use In l e d ~ h l n g tesllllg. experrments. research, or suryery bu l no! ye1 used for such purposes

4. Dogs I

5. C a t s I

7. H a m s t e r s I

10. Sheep I

12. Other F a r m An~mals

13. Oltier An~mals I

I ASSURANCE STATEMENTS

B r a z i l i a n Gray Opossum

RESEARCH F&~LIN (Allitch atlrdrfronal shcels 11 necessary or use APHIS FORM 7023A) '

C Nuntber of D N~~~~~~ ,,I al,llnals upoll E Number o l anlrrlals upon whlch teaching. F. JIIII~IJ~~ upon whlch e x p e r ~ ~ ~ ~ e n t s . exper~ments, research, surgery or tests were wh'ch leJchmg8 leaching, research. conducled lnvolvlng accompanymy pain or dlstress research. suryery, or lesls were

l o Ihe arrlmals and lor whlch Ihe use of approprlale TOTAL experllr'en's, Or c o ~ ~ d u c l e d Involv~ng anesthetic, analgesic, or lranqull lzlng drugs would OF A N ~ M A L ~ lesls were accompanying paln or have adversely allecled the procedures, resulls, or conducled d l ~ l r e s s l o the animals lnlerpretatlon of the leachmg, research, ~ n v o l v ~ n g IIO and lor which appropr,ale exper~ments, surgery. or tests (An explanatron 01 ( ~ 0 1 s . c + pam, drslress, or anesrhellc, allalgeslc, or

the procedures produclrlg pa ln or dlstress rn these D + E) use o l p a w trsllquillrlng drugs were anrrnals a n d the reasons such drugs were not used

rel~evlng drugs. used must b e attached to fhrs report).

15

I 1 ) Prolessrorlally a~cep tab le slandards governing Ihe Care. Irealrnent. and use of anlmdls. ~ n c l u d ~ n g dpprorlrte use 01 dnesthetrc, analgeslc, and l r a n q u ~ l ~ z ~ n g drugs, p r ~ o r lo, during.

and lo l lowlr~y actual research, leaching testlng, surgery, or expernnental~or~ were lollowed by lhlb research Iac l l~ l y

2) Each pr l r~clpal Invesllyalor has constdered a l te r~~a l l ves l o palnlul procedures

31 Thrb I~LIIIIY IS adherlny l o Ihe s l d ~ ~ d d f d s and regula l~ur~s under the ALI and 11 hos requ~red lha l excepllons l o the slandards and regulallons be s p e c ~ l ~ e d and explomed by the PII~I ~ p d l lnvesllydlor and approved by the I n s t l t ~ ~ l r o r ~ d l AnrrnaI Care and Use Comrn~llee IIACUC) A summary of a l l s u c h e r c e p t l o n s 1s a t t a c h e d t o t h l s a n n u a l r e p o r l III addllron to ~ d e n l r l y ~ n g Ihe IACUC approved rxLepllons lhls bulnmdry ~ncludes d brlel explanol~on 01 the excepllons as well as the specleb and number 01 a n l ~ r ~ r l s d l l e ~ l e d

CUH'I'IPICA'I'ION H Y 1IEAI)QUAHTI~:S K E S E A K C I i FACII.I'I'Y O I T I C I A I . (Chief Executive Officer or Legally Ilcsponsiblc Institutional Ollicial)

DATE SIGNED

(b)(6), (b)(7)(C)

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This repad o requued by law (7 USC 2143). Fa~lure lo repod according lo Ihe regulations an

UNITED STATES DEPARTMENT OF AGRICULTURE

ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT OF RESEARCH FACILITY ( TYPE OR PRINT )

1. CERTIFICATE NlJMeER: 31 -R-0114 I FORM APPROVE0 OM0 NO 0579-0036

CUSTOMER NUM8eR: 9423 I Q Test, Ltd Po Box 12381 Columbus, OH 43212 D EC 1 3 2000 Telephone: (614) -486-7001

a I

REPORTING FACILITY ( LISI all locs t iw whare mimals were hwred or used in rdual research. Iesting, or experimentation. or hdd for these purposes. Anach addit'ional sheets 11 necessary ) I

RFPORT OF ANIMALS l lSED RY OR IINDFK

A , B. Numberof / anmats bemg bred.

Annuls Covered ' condlllon&, By The Animal ' held for use on

Weliar. Regulat~onr I teachlnp,

lefbnp. expenmenls research, or surgev but no1 ye

4 Dogs

5 Cats - - 1 --- -

7 Hamsters I . - -

8 Rabbits I

9 Non-human Pnmate I

. . - - , - . - -. . - - . .

10 Sheep . ...

11 Pigs ~ 7. - -. - -

12 Other Farm An~mals I

13 Other Anlmals

INTROI OF RESEARCH FACILITY I Attach additional s k t s if rucasurv o r use APHIS Fo rm 7023A 1 I C. Number of ( 0. Number of anmais I E. Number of arumals upon whlch leaching. i F.

anunsls upon upon whlch i erpmnents rescrrch surgery or tesls were wiwh leachng, 1 expenmenls. leachng. conducted ~nvolwng accompanymg pem or dlslress research. I research surgery. or to Ihe anunds and for W~ICJI the use of appropnale

TOTAL NUMBER

experiments or tests were conducted OF ANIMALS

i anerhebc. malgesr, or trsnqu~llmg drugs would I tests were lnvdnng have edvenely affectad the procedures, results, or conducted sccompanyng pan or Interprelst~on of the teach~ng, research, experiments ( COLUMNS ~nvdwng no d~slreos to the anmals wrgery, or Iests ( An explenat~on of (ha prourdures 1 C + D + E ) pan. d~slress. or and for wh~ch prcduang paln or distress ln these m m a b and the use of pan- sppropr~ats enesthet~c a reams such drugs were no1 used must be anached to rellenng drugs ----I - - - - - - - - . -- -- - - _-

I

I ASSURANCE STATEMENTS & I

1) Rofessaonalty acceptable standards govemmg the care. Irealment, and us3 d mlmals. Wludlng appropnale use of aneatel~c, nalges~c. and t r anquhg drugs, prior lo, dunng. and lollowlng actual research teachmg. testing. surgery. or expenmmtatlon were followed by th~s research factl~ty

5 2) Each prmclpal ~nvesl~gator has consrdered ellernal~ves lo pamful procedures j_ - 3 ) Th6 lactlaty 8s adhenng lo the standards and regulations under the Act. and it has rsgu~red lhal exC8Pllons lo the standards and rrgulations be speufied and explamed by the prlnOpal

lnvesllgalor and approved by the tnst~tutional Anlmat Care and usm Comminee (IACUC) A summary of all such excaptions b a n a c M to thla annual report. In addillon to tdenllfyng the IACUC-approved exceptions, th~s summary mcludes a brief explrnat~on of the excspt~xls, 8s well as Ihe speues and numbat d animals affected.

4 ) The atland~ng velennansn for lhlr research fac8l#ly has appropriate authority to msurs the pronslon 01 adequale velennary care and to oversee the adequacy of olher aspects of anlmal care and

1 CERTIFICATION BY HEADQUARTERS RESEARCH FACILITY OFFICIAL 1 I ( Chief Executive Officer or Legally Responsible Insblulional Official ) I

1 DATE SIGNED

I \-% * .

A P ~ I S ~ R M 7023 (Rep)aces VS FORM 18-23 (OCT 88). whkh IS Obrolate

(AUG91 I

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I I 3 REPORTING F A C l L l N (Llst all localtons where anlrnals were housed or used In aclual research, les1111g leach~ng, or exper~mer~lalrotl, or held lor these purposes Allach a d d l l l ~ l l ~ l

sheets 11 necessary) ,L & ~ t ~ i i j S ~ r l i k a n i s r d in f i d d , qo/- at hi. ~;$u,J FACILITY LOCATIONS d i e s ) fl

Thls reporl 1s ,equlred by law (7 USC 2143) Fa~lure l o reporl accord~ny l o Ihe reLlulallons call See reverse s ~ d e lor I1ttmayel8cy Htp4rI L o ~ l l l u l Nu

result In an order to cease and deslst and l o be sub~ec l to penalt~es as provlded lor 111 Secllon 2150 addl l~onal ~ n l o r m a l ~ o n 0180 OOA AN --

'JNITED STATES DEPARTMENT OF AGRICULTURE ANIMAL AND PLANT HEALTH INSPECTION SERVICE

ANNUAL REPORT OF RESEARCH FACILITY (TYPE OR PRINT)

4. Dogs

5. Cars

6. Gumea P~gs

7. H a m s t e r s

8. R a b b ~ t s

9 Non-human P r m a t e s

10. Sheep

-. 11. Plas

12 O t h e r F a r m An~mals

1 REr.l+TanTlnN Nn 1 9M APPRO B NO 0579~&\' -

2. H I

BHE ENVIROMENTAL, INC

11733 CHESTERDALE RD

CINCINNATI, OH 45246

REPORT OF ANIMALS USED BY OR UNDER CONTROL (

13. O t h e r An~mals

See d+to-~kud

A.

Anmals Covered By The An~mal

Welfare Regulalmns

B Number o l an~mals bemg bred, cond~ l~oned , or held lor use 8n leach~ng, l e s l u ~ g experiments. research. or surgery bu l not ye1 used lor such purposes

I RESEARCH FAClLllT (Aliach d ~ d r t r o r ~ d s t ~ w l s r l neressdrv or use APHIS FORM 7023A) '

3) Thts IJLI~I~Y IS adher~ng l o the s l a ~ ~ d a r d s a11d regulal1uo1s under lhe AGI. atad 11 has requwed (ha! excepllons to Ihe standards and regulations be specllled and e x p l d l ~ ~ e d by Ihe p r ~ n ~ ~ p a l ~nves l~ga lo r aud approved by !he I n s l ~ l ~ ~ l ~ u ~ ~ a l AnllnaI Care and Use Cotnmlllee (IACUC) A s u m n l a y ol a l l s u c h e x c e p l l o n s IS a l l a c h e d t o t h l s annua l r e p o r l 111 a d d ~ l ~ o n l o ldenlrlymg Ihe IACUC approved PxLeptlnns lhla sutnrnary ~ncludes a b r ~ e l explanallon o l the except~ons. as well as the specles and number o l JIIIIIIJI~ al lec led

*

- - -

-

-

-

-

-

-

-

-

4) The allendlng velerwarlall lor I h ~ s research taclllly has approprlale authur~ly l o ensure tho pruvlslolt u l adequale velerlnary care d r ~ d l o oversee the adequacy o l olher aspccls o l ~ ~ l ~ r n a l care m d use

CEKI'IPICA'I'ION I3Y 1IEAI)QUAU'rES KESEAUCtl E'ACII.11'Y OPE'ICIAI. (Chief Execut ive Officer or Legally Hesponsiblc Institutional Ofiicial)

I cer t~ ly fhal Ihe above 1s trlle, correcl, awl c w t ~ p l e l r (7 U S C Secllon 2143)

L (7ype or P r d ) DATE SIGNED

F

TOTAL NO OF A N ~ M A L ~

(cots C + D + E)

-

-

-

-

-

-

-

-

- -

E Number o l anlrnals upon w h h leaching. expertrnenls, research surgery or tests were coriducled mvolvlng accompanymg paln or dlslress to the an~mals and lor whlch Ihe use of approprtate aneslhel~c. analges~c or lranqull lzlng drugs would have adversely a l fec led Ihe procedures, resulls, or ~n le rp re ta t~on of the leach~ng. research. exper~ments, surgery, or tesls (An explanatlon of the procedures producrrly parn or drstress m these anmalf a n d the reasons such drugs were no1 used nlusl be atfached to lhrs reporl)

C Number o l JI I I I~I~~S upon which teaching, research. exVerlmen's, Or

lest5 were conducted ~nvolvmg no patn dstress or use o l paln- rehevlng drugs

- - - -

I

ASSURANCE STATEMENTS

1) Proless~or~ally acceplable slandards governing Ihe care. lrealrnelll, and use o l animals. ~ l ~ c l u d ~ n g approrlate use o l anesthellc, analgesic, and l r a n q u ~ l ~ r ~ n g drugs, prlor lo, durlrlg. and l o l l o w ~ r ~ y actual research, leachmg. lesllng, surgery, or experlrnenlallorl were lollowed by lhls research laclllly.

2) Each pr lnc~pal Invesllgalor has considered allernal~ves l o pa~u lu l procedures

Q Nulnber ol allllnals uL,on whlch experlrrlenls leachlng. research surgery or tesls were conducled lnvolvmg accompanying paln or d~blress 10 l t ~ e a ~ ~ ~ m a l s and for which approprlale anesthellc allalgeslc or lrar,qulllrtng drugs were used

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the POWER of

13. Other animals

8 S H A R E D V A L U E S

C. Number of animals upon which teaching, research, experiments, or tests were conducted involving no pain, distress, or use of pain-relieving drugs. (from APHIS form 7023)

Lasiimrs borealis; Eastern red bat 1 72 Myotis septentrionalis; Northern long-eared bat I 1 Nycticeius humeralis; Evening bat M1,otis grisescens; Gray bat Eptesicusjirscus; Big brown bat Lasiurus cinerius; Hoary bat Pivistrellus subflavus: Eastern ~ i ~ i s t r e l l e

17 1 6 1 2

3 2

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Page 61: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor
Page 62: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor
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Page 64: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor
Page 65: I Xr,,...adhermy lo Ihe aldndards and regulatu~~r unda !he Acl. assd 11 hds reclulred lhal erceplmns lo Ihe stat~dards and regulalmm be spuulled and explaiaal by Ihe prmctpd lnvesl~yalor

(b)(4)

(b)(4)

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(b)(4)

(b)(4)

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(b)(4)

(b)(4)

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(b)(4)

(b)(4)