1 GE confidential

Silicones in Skin Care and Cosmetics

Hydrophilic TOSPEARL

TOSPEARL AQ-05 (XC99-C2075)

Superb sensory to Skin care products

2 GE confidential

What is Hydrophilic TOSPEARL?

TOSPEARL AQ is polymethylsilsesquioxane powder coated with cationic polymer on surface.It can be easily used in O/W type formulation while providing smooth & silky sensory to the skin.

Property TOSPEARL AQ-05

Appearance White powderParticle size (µm) 5.0pH 6.0Specific gravity 1.36

S i O S iOO

S iS i

Me Me

O O

O

MeMe

OS i O OO S i

Me

OMe

Cationic polymer

TOSPEARL

TOSPEARL AQ Structure

3 GE confidential

Characteristics & Application

Characteristics & Application

ApplicationCharacteristics

- O/W Skin care Cream

- O/W Sunscreen & Foundation

- Skin care Lotion

- Body care products

- Water based color cosmetics

- Easily dispersed in water

- Stable at temp below 150℃

- Provide smooth & silky TOSPEARL

- sensory to skin.

4 GE confidential

SEM Picture

×5000

×500

×5000

×500

TOSPEARL 145A TOSPEARL AQ-05

5 GE confidential

Particle analyzer analysis

Particle size: TOSPEARL AQ-05 and TOSPEARL 145A

Particle size (µm)

TOSPEARL AQ-05

TOSPEARL 145A

TOSPEARL AQ-05 has a sharp particle distribution.It has larger particle size (0.6 µm) than TOSPERAL145A.

6 GE confidential

Carmine lotion

After agitation

Composition

Antiseptics

(wt%)Ethanol 9.001,3-Btylene glycol1) 4.50TOSPEARL AQ-05 4.00Sorbitan 1.00(Sorbitol SG, Nikken Chemical)Kaolin1) 0.72Zinc oxide1) 0.60PEG6000 0.50Talk1) 0.48Mica 0.48Magnesium Aluminium Silicate1) 0.42NaCl 0.20Sodium Magnesium Silicate1) 0.06Camphor 0.03Menthol 0.01

q.s.Water 78.01

Materials

Carmine lotion

145AAQ-05

After 1day

145A coagulates

AQ-05 can easily be re-dispersed

145AAQ-05

7 GE confidential

TOSPEARL AQ-05 Physical properties

Stability & Dispersibility

8 GE confidential

Heat resistance

TOSPEARL AQ-05 heat resistance at various temperature for 30min

Blank 105°C 120°C 150°C 200°C 250°C

TOSPEARL AQ-05 is stable under 150℃.

9 GE confidential

Stability

Stability results on various condition (10wt% TOSPEARL AQ-05 suspension)

Condition Median (µm) Condition Median (µm)

2.5wk 4wk 2.5wk

5.56 5.51

5.00

4.98

5.17

5.80

5.46

5.81

C1) 4.97 4.96 4.93 pH54) 5.92 5.83 5.79 5.60

5.76

5.72

5.62

4.94

4.95

6.06

5.46 4.94

0wk 1wk 0wk 1wk 4wk

H2O 5.84 5.92 pH34) 6.03 5.82 5.60

A2) 4.97 4.96 pH74) 5.89 5.79 5.60

N3) 4.98 4.89 pH94) 5.75 5.75 5.58

20% EtOH aq. 6.00 5.96 pH114) 5.48 5.56 5.60

50% EtOH aq. 5.53 5.45 pH134) 5.71 4.90 5.98

1) 1wt% of cationic emulsifier aq., 2) 1wt% of anionic emulsifier aq., 3) 1wt% of nonionic emulsifier aq.4) pH controller: NaOH and HCl

TOSPEARL AQ-05 is stable at wide range of pH over 4 weeks at 50℃.It is also stable in Ethanol suspension.

10 GE confidential

Dispersibility in H2O

Dispersibility in water (10wt% TOSPEARL AQ-05 suspension)

10%wt TOSPEARL AQ-05 & 145A were added to H2O to observe the dispersibility. The suspension was agitated 40 times and then kept stationary for 24 hours.

Before agitation After agitation After 24 hours

TOSPEARL145A

Easy to re-disperse

TOSPEARLAQ-05

TOSPEARL145A

TOSPEARLAQ-05

TOSPEARLAQ-05

TOSPEARL145A

TOSPEARLAQ-05

TOSPEARL145A

TOSPEARL AQ-05 can easily be re-dispersed TOSPEARL AQ-05 can easily be re-dispersed

11 GE confidential

Dispersibility (pH)

Dispersibility of TOSPERAL AQ-05 at various pH conditions

After shaking for 5 minAfter added

After 1 day

TOSPEARL AQ-05 shows good dispersibility at pH 3-11 condition(pH controller: NaOH and HCl)-10wt% TOSPEAL AQ-05 suspension-

12 GE confidential

Blank(Only water)

Dispersibility of TOSPEARL AQ-05 in various Water / oil solution

Cyclopentasiloxane

DMF-10ｃｓ

Isoparafin

Caprylic/Capric Triglyceride

Isononyl-isononaete

Squalane

Condition:1. 10wt% of TOSPEARL AQ-05 was added to oil/water mixture.2. Agitated by ultrasonic wave for 5 min3. Kept at R.T. for 1hour.

Dispersibility (oil/water)

Oil phase

Water phase

TOSPEARL AQ-05 remains dispersed in the aqueous phase.