1. 1. 1 TRNG I HC TR VINH KHOA: NNG NGHIP- THY SN B MN: CHN NUI TH Y MN: BNH K SINH TRNG CHUYN : HUYT BO T TRNG GVHD: Nguyn Th u SVTH: L Minh Thng Hunh Th Hunh Nh
2. 2. I- GII THIU CHUNG V HUYT BO T TRNG 1. Khi nim L nhng n bo k sinh trong hng cu gia sc. 2
3. 3. 3 2. Nguyn nhn gy bnh Do n bo thuc h Babesiidae (Babesia bigemina, Babesia bovis) hay cn gi l bnh l dng trng. Do n bo thuc h Anaplasmidae (Anaplasma marginale) hay cn gi l bnh bin trng.
4. 4. 4 Babesia tru b B.bigemi na B.bovis B.divergs B.major B.argenta Babesia d cu B.motasi B.ovis B.foliata B.taylori Babesia nga B.caballi B.equi Babasia heo B.trauman ni B.perronci toi Babesia ch mo B.canis B.gibsoni B.vogeli B.felis 3. Phn loi ging Babesia gy bnh cc loi
5. 5. 1. c im * c im hnh thi - Babesia bigemina (Piroplasma bigerminum): Merozoite trong hng cu c dng hnh l, trn, oval. + Dng trn: 2 3 m. + Dng di: 4 5 m x 2 m - Babesia bovis: Merozoite c dng hnh l, hnh trn. Kch thc 2,4 x 1,5 m. II- BABESIA B (L DNG TRNG) 5
6. 6. * Cch truyn bnh Qua trung gian l cc loi ve thuc cc ging: - Boophilus - Rhipicephalus - Haemaphysalis - Dermacentor - Amblyomma - Aponomma.6
7. 7. 7 Boophilus
8. 8. 8 Rhipicephalus
9. 9. 9 Haemaphysalis
10. 10. 10 Amblyomma Female Male
11. 11. 11 Ve ht mu tru b bnh rut microgamete + macrogamete zygote t bo biu m rut sporozoite ng Malpighi, h thng bch huyt nhiu sporozoite khc bung trng tuyn nc bt phn chia Merozoite, microgametocyte, macrogametocyte Sinh sn v tnh 2. Vng i
12. 12. 12 Ve mang mm bnh ht mu tru b khe sporozoite hng cu b 2 merozoite hng cu b ph v, microgametocyte v macrogametocyte Phn i
13. 13. 13
14. 14. 14
15. 15. Vit Nam: 1908: B.bigemina c b Trung B, Bc B 1921 1924: tru b nhim Bc B, Nam B, Ninh Bnh, Hi Phng. 1958 1960: bnh xut hin qu na s tnh min Bc. 1963: nng trng Ba V. B.bigemina: T l hng cu b nhim cao nht 10%, thp nht 3 5%. B.bovis: T l hng cu b nhim cao nht 20%, thp nht 8%. 3. Dch t 15
16. 16. 4. Triu chng Thi k nung bnh B.bigemina t 9 15 ngy c khi n 35 ngy, B.bovis t 7 18 ngy. - St cao 39,80C c khi ln n 42,20C. - Thiu mu. - C haemoglobin niu, nc tiu c mu nu . - B n, nhp tim tng, chy nc mt, nc mi, lng sa gim hn. - Tiu chy, phn mu vng. - Co git, hn m, tn cng bt c vt g. 16
17. 17. - Cc ni tng v tht nht nht. - Ti mt sung, dch mt v huyt sc t. - Nim mc b hong n. - Tim sng to, nht nht. - Phi c ph thng nh. - Gan sng to mu vng nu. - D l sch kh cng. 5. Bnh tch 17
18. 18. - Nim mc nht nht 18
19. 19. - Diminazene aceturate (Berenyl). - Quinaronium sulfate. - Acridine v cc dn xut acriflavine, gonacrine, euflavine, trypaflavine, flavaridine. - Haemosporindin. - Trypan bleu. - Pentamidine isethionate. - Phenamidine isethinate. - Amicarbalide diisethionate. - Imidicarb dipropianate. - Ludobal. - Dimidine. 6. iu tr 19
20. 20. - Thc hin cc bin php phng chng ve gia sc. - Duy tr c trng thi min dch hoc a gia sc vo nhng vng c ve s to c trng thi min dch tng i. - Dng vaccine chch cho gia sc. - Dng cc thuc trn chch cho gia sc. 7. Phng bnh 20
21. 21. 21 Triu chng: khng in hnh t thy haemoglobin St 39,5 41,80C Nim mc vng hong n Hai chn sau bi lit Th nhanh Tiu chy Thn kinh III- BABESIA CC LOI KHC 1. nga * Triu chng
22. 22. * Bnh tch: - Bp tht nht nht. - Ni tm mc xut huyt lm tm. - Phi nc. - L lch, cc hch lm ba sng to, mm. - Gan sng to mu nu vng. - Nim mc ng tiu ha xut huyt. - Thn vng c lm tm xut huyt. 22
23. 23. 23 2. ch, mo * Triu chng Thi k nung bnh: 6 20 ngy Vt t n St 41 420C Nim mc vng Sau 2 3 ngy: huyt sc t trong nc tiu
24. 24. 3. d, cu * Triu chng 24 Thi k nung bnh: 9 14 ngy St 42,20C Vt yu dn, hay nm, lit d c Thiu mu Nc tiu: mu nu ti, nhiu haemoglobin
25. 25. * Bnh tch: - Nim mc vng. - L lch sng to. - Tim, phi, rut xut huyt. - Gan thm mu. - Thn sng. - Nc tiu mu vng hay .25
26. 26. 1. Dch t III- BIN TRNG 26 ng vt cm nhim: tru, bo, d, cu, hu, nai, lc a. Cac loai vt khac khng cm thu. Mi loai bin trung co vt chu chuyn bit. tui va ging bo cng khac nhau v tinh cm th.
27. 27. III- BIN TRNG 27 Vt chu trung gian truyn bnh: Cac cn trung ky sinh tru bo ong vai tro quan trng trong vic ly truyn bnh bin trung: MuiRuiVe
28. 28. 2. Phn b III- BIN TRNG 28 Bnh co bo hu ht cac nc trn th gii. Vit Nam phat hin thy Anaplasma trong mau bo, cu va d Trung Nam B (1931), Bc B (1938), Ty Nguyn Nha Trang, a Lt (1930-1940),
29. 29. 3. c im hinh thai. III- BIN TRNG 29 Bin trung H anaplas -midae Ky sinh trong hng cu Hinh cu Hinh trng Phat hin 2 loai bo A.Margi nale-ria hng cu A.Central e-tm hng cu
30. 30. 30 III- BIN TRNG
31. 31. 31 III- BIN TRNG
32. 32. 32 Anaplasma-marginale
33. 33. 4. Vong i Co 2 giai on phat trin: III- BIN TRNG 33 V tinh Hu tinh
34. 34. * Giai on v tinh: c thc hin trong c th vt chu. Chung sinh sn trong hng cu theo phng thc phn chia. 34 III- BIN TRNG
35. 35. * Giai on hu tinh: Din ra vt chu trung gian bao gm mt s loai ve thuc h ve Ixodidac, Boophilus. Mt s loai cn trung khac cng cng co th truyn mm bnh bng con ng c gii: mong, rui, mui. 35 III- BIN TRNG
36. 36. 36 Ixodus ricinus
37. 37. 37 Ixodus ricinus
38. 38. 38 Boophilus microplus Boophilus microplusfed female
39. 39. 39 Boophilus microplus
40. 40. 40 Boophilus-females
41. 41. * Giai on hu tinh: Theo Kendall va Richarson (1986): 41 Ve Bin trung Hch bch huyt Vach ng tiu hoa Bao t Tuyn nc bt Bung trng
42. 42. 42
43. 43. 43 Bao t bin trung trong c th ve
44. 44. 44
45. 45. 5. Triu trng III- BIN TRNG 45 Thi gian nung bnh: 7 14 ngay Co 2 th bnh thng thy: Cp tinh Man tinh
46. 46. III- BIN TRNG 46 Th cp tinh Bnh phat ra d di, st cao 40 41.50C T l cht cao (t ngay th 7 sau nhim bnh). Th gp, tim p nhanh va mnh. Kem n, gim nhai li, gim nhu ng d c.
47. 47. III- BIN TRNG 47 Do hng cu b v va gim mnh, cac nim mc mt, ming nht nht, i khi co hoang ng. Bo cai khi phat bnh gim hoc ngng tit sa
48. 48. III- BIN TRNG 48 Bnh tich: - Bo gy, mau loang, nht nht - Hch lm ba trc vai va ui sng, tu huyt, thuy thng. - Tim to, nht nht, co chm xut huyt. - D c, d t ong nim mc b rp, d la sach kh cng d boc.
49. 49. III- BIN TRNG 49 - Lach sng mm, mt sng to.
50. 50. III- BIN TRNG 50 Th man tinh: Biu hin lm san ging th cp tinh. Nhng mc nhe hn. Bo st 39 400C khong 7 10 ngay sau o gim, ri li tang ln. Keo dai 20 30 ngay hoc hn. Kem n, gy com, suy nhc, Nu khng c chm soc tt, vt s cht do kit sc.
51. 51. III- BIN TRNG 51 Mt s trng hp bo th hin trng thai mang trung ong vai tro lu tr va truyn ba mm bnh trong t nhin.
52. 52. 6. iu tr III- BIN TRNG 52 S dng - Haemosporidin 0.5mg/P - Trypaflavin 3 4mg/P - Hn hp: Rivanol 0.2g, cn 900 60ml, nc ct 120ml.
53. 53. 7. Phong bnh III- BIN TRNG 53 - nh ky chn oan bnh - Dung hoa dc tim phong trc mua ly lan va phat bnh cho bo sa trong vung dch t ( thang 10). - T chc dit ve nh ky, thc hin v sinh thu y, mi trng. - Nui dng, chm soc tt.
54. 54. 54 Thank you !
55. 55. 55